Receptor
PDB id Resolution Class Description Source Keywords
3GJX 2.5 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE NUCLEAR EXPORT COMPLEX CRM1- SNURPORTIN1-RANGTP HOMO SAPIENS TRANSPORT CYTOPLASM NUCLEUS RNA-BINDING ACETYLATION GTP-BINDING HOST-VIRUS INTERACTION NUCLEOTIDE-BINDING PHOSPHOPROTEIN POLYMORPHISM PROTEIN TRANSPORT MRNA TRANSPORT
Ref.: CRYSTAL STRUCTURE OF THE NUCLEAR EXPORT RECEPTOR CRM1 IN COMPLEX WITH SNURPORTIN1 AND RANGTP. SCIENCE 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CL E:362;
Invalid;
none;
submit data
35.453 Cl [Cl-]
GTP C:217;
F:217;
Valid;
Valid;
none;
none;
submit data
523.18 C10 H16 N5 O14 P3 c1nc2...
MG C:218;
F:218;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
NA B:361;
E:361;
Part of Protein;
Part of Protein;
none;
none;
submit data
22.99 Na [Na+]
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3GJX 2.5 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE NUCLEAR EXPORT COMPLEX CRM1- SNURPORTIN1-RANGTP HOMO SAPIENS TRANSPORT CYTOPLASM NUCLEUS RNA-BINDING ACETYLATION GTP-BINDING HOST-VIRUS INTERACTION NUCLEOTIDE-BINDING PHOSPHOPROTEIN POLYMORPHISM PROTEIN TRANSPORT MRNA TRANSPORT
Ref.: CRYSTAL STRUCTURE OF THE NUCLEAR EXPORT RECEPTOR CRM1 IN COMPLEX WITH SNURPORTIN1 AND RANGTP. SCIENCE 2009
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 3GJX - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 3GJX - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 3GJX - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GTP; Similar ligands found: 147
No: Ligand ECFP6 Tc MDL keys Tc
1 GTP 1 1
2 GP3 0.921053 0.973684
3 GDP 0.909091 1
4 GSP 0.853659 0.948718
5 GNH 0.82716 0.986667
6 G1R 0.819277 0.986667
7 GAV 0.811765 0.961039
8 GNP 0.809524 0.973684
9 GCP 0.797619 0.973684
10 5GP 0.797468 0.986486
11 G 0.797468 0.986486
12 GMV 0.764706 0.973684
13 G2R 0.764045 0.961039
14 G5P 0.755319 0.973684
15 GTG 0.752688 0.936709
16 G2P 0.747126 0.961039
17 G3A 0.744681 0.973684
18 GDD 0.741935 0.961039
19 GKE 0.741935 0.961039
20 GDC 0.741935 0.961039
21 0O2 0.736264 0.986486
22 GP2 0.729412 0.961039
23 6CK 0.726316 0.936709
24 Y9Z 0.723404 0.902439
25 GPG 0.717391 0.961039
26 GFB 0.715789 0.961039
27 GDR 0.715789 0.961039
28 GDP MG 0.712644 0.923077
29 GDP BEF 0.704545 0.9
30 GPD 0.704082 0.925
31 JB2 0.693878 0.961039
32 GKD 0.693878 0.961039
33 GCP G 0.692308 0.935065
34 GDX 0.686869 0.973684
35 ALF 5GP 0.685393 0.888889
36 GTP MG 0.681319 0.923077
37 BEF GDP 0.681319 0.888889
38 GH3 0.681319 0.973333
39 YGP 0.677083 0.901235
40 G3D 0.67033 0.986486
41 GDP AF3 0.659574 0.888889
42 GDP ALF 0.659574 0.888889
43 DGT 0.659341 0.923077
44 GMP 0.658228 0.88
45 G4P 0.655914 0.986486
46 JB3 0.653846 0.948718
47 NGD 0.647619 0.961039
48 CAG 0.642202 0.880952
49 2MD 0.62963 0.891566
50 G G 0.622449 0.935065
51 MGP 0.619565 0.961039
52 U2G 0.616822 0.936709
53 6G0 0.612903 0.961039
54 MGD 0.612613 0.891566
55 TPG 0.608696 0.840909
56 CG2 0.605505 0.936709
57 GDP 7MG 0.601942 0.911392
58 FEG 0.601852 0.879518
59 ZGP 0.59633 0.869048
60 MD1 0.591304 0.891566
61 PGD 0.591304 0.925
62 3GP 0.590909 0.946667
63 GPX 0.581633 0.946667
64 DGI 0.580645 0.923077
65 IDP 0.576087 0.972973
66 DBG 0.567797 0.948718
67 FE9 0.555556 0.776596
68 2GP 0.555556 0.96
69 G4M 0.547619 0.880952
70 BGO 0.544643 0.924051
71 I2C FE2 CMO CMO 0.538462 0.808989
72 ATP 0.537634 0.92
73 G1G 0.533898 0.925
74 AQP 0.531915 0.92
75 5FA 0.531915 0.92
76 G A A A 0.525862 0.923077
77 U A G G 0.521368 0.935065
78 01G 0.518868 0.902439
79 ITT 0.510638 0.868421
80 P2G 0.510638 0.883117
81 GGM 0.504274 0.901235
82 G1R G1R 0.504065 0.924051
83 DGP 0.5 0.910256
84 PGD O 0.5 0.850575
85 MGO 0.5 0.864198
86 P1G 0.5 0.871795
87 DG 0.5 0.910256
88 GTA 0.495495 0.936709
89 B4P 0.489362 0.894737
90 AP5 0.489362 0.894737
91 IMP 0.489362 0.959459
92 7DT 0.484536 0.906667
93 G G U 0.482143 0.935065
94 GPC 0.479339 0.879518
95 G C 0.478992 0.9
96 BA3 0.478723 0.894737
97 ADP 0.473684 0.92
98 G2Q 0.471698 0.961039
99 G7M 0.46875 0.948052
100 25L 0.458716 0.907895
101 A2D 0.457447 0.894737
102 RGT 0.45045 0.909091
103 AGS 0.45 0.873418
104 SAP 0.45 0.873418
105 SGP 0.44898 0.82716
106 U G A 0.448529 0.888889
107 A4P 0.445378 0.869048
108 G G G RPC 0.442623 0.875
109 ACQ 0.441176 0.896104
110 ANP 0.441176 0.896104
111 8GT 0.441176 0.875
112 APC G U 0.44 0.886076
113 G U34 0.438017 0.888889
114 6AD 0.436893 0.841463
115 G G G C 0.433071 0.9125
116 UP5 0.432203 0.873418
117 35G 0.431373 0.933333
118 C2E 0.431373 0.921053
119 PCG 0.431373 0.933333
120 A G C C 0.429688 0.911392
121 5GP 5GP 0.427184 0.883117
122 TAT 0.427184 0.884615
123 APR 0.425743 0.894737
124 AR6 0.425743 0.894737
125 AN2 0.424242 0.907895
126 7DD 0.424242 0.906667
127 DG DG 0.423423 0.865854
128 AD9 0.421569 0.896104
129 M33 0.42 0.883117
130 7D4 0.42 0.835443
131 UCG 0.419847 0.911392
132 H6Y 0.419048 0.946667
133 G C C C 0.416667 0.924051
134 ACP 0.415842 0.896104
135 T5A 0.414634 0.802326
136 MGQ 0.412844 0.935897
137 ADQ 0.412844 0.871795
138 A1R 0.412844 0.839506
139 MGT 0.411215 0.823529
140 A G U 0.410072 0.888889
141 93A 0.41 0.833333
142 A22 0.407407 0.907895
143 CA0 0.405941 0.896104
144 ATF 0.40566 0.884615
145 AGO 0.404762 0.888889
146 MGV 0.401786 0.890244
147 CGP 0.4 0.86747
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3GJX; Ligand: GTP; Similar sites found: 432
This union binding pocket(no: 1) in the query (biounit: 3gjx.bio1) has 27 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2Y65 ADP 0.00001215 0.59221 3.0137
2 5I34 GDP 0.00005178 0.52847 3.24074
3 2ZR9 DTP 0.0001036 0.52031 3.24074
4 2ZPA ADP 0.001024 0.44732 3.24074
5 4TQK NAG 0.03188 0.40541 3.44828
6 3VM7 GLC 0.01554 0.41367 3.56164
7 1U2Z SAH 0.003903 0.40834 3.56164
8 2B1N LYS ALA SER VAL GLY 0.02788 0.40323 3.65854
9 2C77 GNP 0.0000000001329 0.74259 3.7037
10 2C78 GNP 0.0000000001379 0.73213 3.7037
11 5LB3 ADP 0.0005027 0.49225 3.7037
12 4TTQ ATP 0.00009072 0.52317 3.72093
13 3RC3 ANP 0.003707 0.44808 3.83562
14 4AG5 ADP 0.0000333 0.56614 4.10959
15 4YS0 ADP 0.002209 0.43642 4.10959
16 2FAH GDP 0.001174 0.45326 4.16667
17 4FCW ADP 0.001061 0.46493 4.18006
18 3WXM GTP 0.0000000001975 0.69891 4.25056
19 1W5T ANP 0.002202 0.42882 4.36893
20 1W5T ADP 0.004839 0.42096 4.36893
21 3IUY AMP 0.0106 0.42045 4.38596
22 3BER AMP 0.01039 0.4209 4.41767
23 1JI0 ATP 0.00002355 0.56805 4.58333
24 3DZD ADP 0.0008775 0.45912 4.61957
25 3KJI ADP 0.00006747 0.5107 4.62963
26 5GJC ATP 0.00009019 0.5233 4.65753
27 2JLR ANP 0.0002288 0.48615 4.65753
28 4LJ9 ACP 0.001882 0.4578 4.71976
29 5DT6 GLU 0.03387 0.40487 4.86891
30 1R6B ADP 0.0001646 0.50414 4.88127
31 4WOP CTP 0.0002224 0.47211 4.88889
32 3LN9 FLC 0.003954 0.45202 5.03597
33 3BFX A3P 0.006052 0.41304 5.06757
34 1G6H ADP 0.0000006074 0.68186 5.09259
35 2AWN ADP 0.0000009529 0.67436 5.09259
36 1YQT ADP 0.00003753 0.56386 5.09259
37 1G41 ADP 0.0002586 0.489 5.09259
38 2XAU ADP 0.0002877 0.48681 5.09259
39 1OFH ADP 0.0003379 0.48351 5.09259
40 2PW0 TRC 0.01233 0.43254 5.09259
41 2ATJ BHO 0.01895 0.41258 5.09259
42 3DCJ THH 0.01104 0.40811 5.11628
43 2X7I CIT 0.008384 0.42554 5.19481
44 1V8K ANP 0.0000004302 0.63849 5.20548
45 4B47 GDP 0.0000000002094 0.81682 5.23416
46 1XX6 ADP 0.0006122 0.48202 5.2356
47 5TSH ADP 0.00007622 0.54653 5.27211
48 5TSH ANP 0.00009921 0.52124 5.27211
49 1BO4 COA 0.01234 0.41717 5.35714
50 2C04 GCP 0.00005276 0.50992 5.38721
51 1XP8 AGS 0.0002698 0.506 5.46448
52 5N69 ADP 0.00001952 0.53564 5.52764
53 3MD0 GDP 0.000000004188 0.75064 5.55556
54 4LC1 GDP 0.00000003738 0.69114 5.55556
55 1OYY AGS 0.002829 0.44901 5.55556
56 3QOX SAH 0.004244 0.40684 5.6338
57 3VX3 ADP 0.0001751 0.48135 5.64516
58 4IEE AGS 0.0002032 0.51227 5.71429
59 3TK1 GDP 0.00000000971 0.74475 5.75758
60 3B5J 12D 0.000007897 0.59283 5.76132
61 1H5R THM 0.02236 0.40425 5.80205
62 4ZNL BEF ADP 0.0003718 0.48699 5.83942
63 1D2N ANP 0.005717 0.41078 5.88235
64 5GVR LMR 0.00006502 0.56471 5.98291
65 1WF3 GNP 0.00000000266 0.64613 6.01852
66 3COB ADP 0.000003032 0.62515 6.01852
67 1RRC ADP 0.000006898 0.60987 6.01852
68 4FRZ ADP 0.000006725 0.60314 6.01852
69 1F9V ADP 0.00001087 0.59171 6.01852
70 3E70 GDP 0.000004091 0.58188 6.01852
71 4H1V GNP 0.000008024 0.54697 6.01852
72 4IDN GNP 0.00008774 0.48489 6.01852
73 2DPY ADP 0.001651 0.47169 6.01852
74 1QAN SAH 0.0008296 0.43955 6.01852
75 2HF9 GSP 0.00000003986 0.65134 6.19469
76 2CHG ANP 0.0003471 0.47285 6.19469
77 3NHB ADP 0.00001117 0.59294 6.20915
78 4R43 GDP 0.002137 0.45506 6.30137
79 4IP7 FBP 0.00994 0.41022 6.30137
80 1L2T ATP 0.0006784 0.43951 6.38298
81 2D2F ADP 0.00002899 0.58747 6.4
82 1IHU AF3 0.0001136 0.48011 6.45161
83 1IHU ADP 0.0001274 0.47354 6.45161
84 4PX9 ADP 0.0002871 0.50463 6.48148
85 2BEK ATP 0.0001722 0.47241 6.48148
86 1IN4 ADP 0.0005997 0.45763 6.48148
87 1YTM ATP 0.0004861 0.45735 6.48148
88 5X40 ACP 0.0006421 0.41859 6.48148
89 5MEX PAP 0.01173 0.40024 6.48148
90 5NUL FMN 0.01083 0.40506 6.52174
91 3DKP ADP 0.000726 0.47834 6.53061
92 4HSE ADP 0.00007216 0.52149 6.57534
93 3BOS CDP 0.0001374 0.51422 6.61157
94 2IXE ATP 0.0003603 0.45875 6.64207
95 3FVQ ATP 0.0004112 0.46051 6.68524
96 2F5X ASP 0.02718 0.40789 6.73077
97 1G3Q ADP 0.00001706 0.55183 6.75105
98 2HXW FLC 0.02484 0.40995 6.75105
99 3P4X ADP 0.00009374 0.52936 6.77966
100 3QKT ANP 0.0004384 0.44729 6.78466
101 4CVN ADP 0.00005341 0.54949 6.80628
102 5KSZ GCP 0.000002364 0.58554 6.84932
103 3W5J GDP 0.0000002251 0.6838 6.86275
104 2PMP C5P 0.03557 0.40453 6.875
105 3DC4 ADP 0.000001447 0.6313 6.94444
106 1P9B GDP 0.000148 0.48962 6.94444
107 2CE7 ADP 0.0002759 0.48768 6.94444
108 1XKV ATP 0.0002767 0.48762 6.94444
109 1K6M AGS 0.001184 0.43309 6.94444
110 2GMP NAG MAN 0.02089 0.41693 6.94444
111 4GOX A3P 0.003568 0.41306 6.94444
112 3B7G ANP 0.00155 0.45693 6.95652
113 3UIE ANP 0.00005995 0.51906 7
114 2GK6 ADP 0.005044 0.44633 7.05128
115 5MZN ADP 0.003481 0.45475 7.12329
116 4IOK XPO 0.002944 0.41336 7.12329
117 4QRH 0O2 0.006327 0.40886 7.14286
118 3FJG 3PG 0.01775 0.41927 7.17131
119 2HK9 ATR 0.01967 0.40703 7.27273
120 1KK1 GNP 0.000000009667 0.73216 7.31707
121 1GOJ ADP 0.000001101 0.65493 7.32394
122 2ZJ5 ADP 0.02577 0.41153 7.36111
123 2NCD ADP 0.00001331 0.58684 7.38095
124 1BH2 GSP 0.0000000005393 0.65021 7.40741
125 1SVK ALF GDP 0.0000000009577 0.63063 7.40741
126 1W0J ADP 0.0001302 0.49748 7.40741
127 3TBK ANP 0.004616 0.44834 7.40741
128 1W0J ADP BEF 0.001233 0.44373 7.40741
129 2FSH ANP 0.004907 0.44187 7.40741
130 1T9D P22 0.00839 0.43475 7.40741
131 1QHG ATP 0.006448 0.41896 7.40741
132 1AQU A3P 0.00793 0.41121 7.40741
133 4U60 SIA 0.02235 0.40871 7.5
134 3KTA AP5 0.0008399 0.45999 7.51445
135 3R7F CP 0.02499 0.41212 7.56579
136 3T1O GDP 0.00000007654 0.65607 7.57576
137 3RLF ANP 0.0005783 0.4461 7.63158
138 4KBF AMP 0.003024 0.45259 7.67123
139 5L3V GDP 0.000004409 0.57272 7.69231
140 3KC1 2T6 0.003684 0.42263 7.71513
141 3CX8 GSP 0.0000000003392 0.65747 7.87037
142 2OG2 MLI 0.00003086 0.56557 7.87037
143 2QZ4 ADP 0.0003193 0.48467 7.87037
144 1TE2 PGA 0.02784 0.40843 7.9646
145 3ITJ CIT 0.0101 0.43171 7.98817
146 1TL2 NDG 0.01541 0.42088 8.05085
147 4A4Z ANP 0.01166 0.41839 8.21918
148 3B9Q MLI 0.00004787 0.55269 8.27815
149 2VVG ADP 0.00000147 0.64673 8.28571
150 1FP6 ADP 0.00004719 0.51789 8.3045
151 1AZT GSP 0.0000000001538 0.67038 8.33333
152 4P4T GDP 0.000004504 0.55187 8.33333
153 3FWY ADP 0.00001598 0.53341 8.33333
154 1B7T ADP 0.00004914 0.52315 8.33333
155 1XMV ADP 0.000154 0.50554 8.33333
156 4PJ3 ANP 0.004037 0.4284 8.33333
157 5SXS NIZ 0.01876 0.40336 8.33333
158 1CM0 COA 0.0174 0.40229 8.33333
159 2XTZ GSP 0.00000000006691 0.71783 8.49315
160 2Q8M AMP 0.0005918 0.47721 8.49315
161 2WJG GDP 0.00000001751 0.70748 8.51064
162 1G7C 5GP 0.0000006008 0.63129 8.51064
163 4U00 ADP 0.000001581 0.65599 8.60656
164 1TAD ALF 0.000000001179 0.63819 8.64198
165 1TAD GDP 0.000000001179 0.63819 8.64198
166 2XT3 ADP 0.000003154 0.62455 8.72093
167 1VBO MAN 0.009074 0.42761 8.72483
168 1OS1 ATP 0.002382 0.40088 8.76712
169 4QOS ADP 0.001028 0.46063 8.7963
170 3BFV ADP 0.00007523 0.5272 8.85609
171 3H4S ADP 0.000003217 0.62493 8.88889
172 2C9O ADP 0.0001836 0.47573 8.99123
173 5KUT GDP 0.0000001384 0.65313 8.99471
174 2WJH GDP 0.000000007571 0.71427 9.03614
175 2WJH FLC 0.0000006112 0.61335 9.03614
176 5E5U MLI 0.004457 0.40398 9.04523
177 1WY7 SAH 0.004268 0.4098 9.17874
178 1NJF ADP 0.0002504 0.47446 9.2
179 1NJF AGS 0.0003181 0.46106 9.2
180 3EC1 GDP 0.00000002742 0.68719 9.21409
181 1JJV ATP 0.0001675 0.52676 9.2233
182 1SVI GDP 0.000000002855 0.75911 9.23077
183 1PUJ GNP 0.000000004543 0.70384 9.25926
184 4NON GDP 0.0000001881 0.56305 9.25926
185 2ZFI ADP 0.00002163 0.55407 9.28962
186 3AI8 HNQ 0.03473 0.40224 9.375
187 4KFU ACP 0.000003047 0.62216 9.43396
188 5L3W GDP 0.00001281 0.55079 9.47712
189 4HI0 GDP 0.0000008611 0.57694 9.54774
190 4P32 ADP 0.0021 0.42612 9.63855
191 3ZFD ANP 0.00000004402 0.66744 9.68661
192 2ZL4 ALA ALA ALA ALA 0.03662 0.40169 9.69388
193 4RD0 GDP 0.00000000001822 0.76958 9.72222
194 4LPS GDP 0.0000002783 0.63843 9.72222
195 2WHX ADP 0.00002526 0.57355 9.72222
196 1ION ADP 0.00003476 0.53027 9.72222
197 1U0J ADP 0.0002857 0.50474 9.73783
198 1FNZ A2G 0.02709 0.40708 10.1266
199 5FG3 GDP 0.0000000006608 0.79143 10.1852
200 1Z6T ADP 0.0005492 0.46382 10.1852
201 1YBH P22 0.02092 0.40569 10.1852
202 3KIH GDL 0.02928 0.40618 10.3093
203 1QHH ATP 0.01224 0.41335 10.4348
204 3MBI HSX 0.02991 0.40166 10.453
205 4IHQ ADP 0.000247 0.50796 10.5263
206 1M26 GAL A2G 0.04532 0.4 10.5263
207 1JWY GDP 0.000003715 0.569 10.6481
208 1JWY ADP 0.0000116 0.55995 10.6481
209 2IS6 ADP 0.0001873 0.50754 10.6481
210 4D81 ADP 0.000521 0.4696 10.6481
211 3FYH ADP 0.003201 0.41187 10.6481
212 1KK8 BEF ADP 0.000008547 0.54573 10.7914
213 1FNN ADP 0.0003015 0.47088 10.7969
214 2WOJ ADP ALF 0.00008492 0.46822 11.0169
215 4XTR ADP 0.00009188 0.49378 11.0599
216 4XTR ATP 0.0001088 0.47641 11.0599
217 4XVU ATP 0.0001263 0.4737 11.0599
218 1LVG ADP 0.000004263 0.60681 11.1111
219 5BQ5 ADP BEF 0.0002752 0.48772 11.1111
220 4YMU ATP 0.00001862 0.56508 11.25
221 1CS4 GSP 0.0000000002074 0.67757 11.3208
222 1KO8 6PG 0.001074 0.44641 11.4286
223 2VB6 ADP BEF 0.00003065 0.4994 11.5068
224 4PFO ADP 0.0001036 0.46881 11.5068
225 1EXF GLY 0.008663 0.41007 11.5702
226 1X6V ADP 0.0009891 0.4153 11.5741
227 1UJ2 C5P 0.004252 0.40105 11.5741
228 5KSP GDP 0.000002364 0.59342 11.5789
229 2QEN ADP 0.0002648 0.47817 11.7143
230 1SKQ GDP 0.00000003057 0.70672 11.7241
231 4O48 ASP 0.01517 0.42347 11.747
232 2W58 ADP 0.000002307 0.64377 11.8812
233 4BQS ADP 0.00007317 0.5278 11.9318
234 2CK3 ANP 0.001194 0.44436 12
235 2CK3 ADP 0.001645 0.42712 12
236 2BVN GNP 0.0000000003607 0.75478 12.037
237 1D8T GDP 0.00000000557 0.73216 12.037
238 2Z5F A3P 0.007862 0.40474 12.037
239 1I9G SAM 0.008467 0.40027 12.037
240 2ODE ALF GDP 0.0000000004356 0.65401 12.3288
241 3ZQ6 ADP ALF 0.00007096 0.4713 12.3457
242 5CK5 GDP 0.00000000009804 0.83358 12.5
243 2RCN GDP 0.0000000001615 0.80847 12.5
244 2IYL GDP 0.000005339 0.58422 12.5
245 1OXV ANP 0.00004199 0.54711 12.5
246 2GDJ ANP 0.00008882 0.52363 12.5
247 2B8W ALF 5GP 0.000007266 0.52027 12.5
248 1NY5 ADP 0.002162 0.43684 12.5
249 4MZQ 1VU 0.005218 0.41591 12.5
250 1NRJ GTP 0.0000000001028 0.74745 12.6582
251 1F2U ATP 0.0008538 0.42862 12.7517
252 5L3S GNP 0.00002513 0.49819 12.8378
253 5L3S G 0.03096 0.40952 12.8378
254 4NCN GTP 0.00000000001234 0.76658 12.963
255 5HCN GCP 0.000000002113 0.74112 12.963
256 1G7S GDP 0.0000000166 0.69775 12.963
257 1DAR GDP 0.00000005158 0.6842 12.963
258 1T5C ADP 0.000003735 0.6246 12.963
259 1H65 GDP 0.000007978 0.52925 12.963
260 1YRB GDP 0.0000000004335 0.75108 12.9771
261 1ZUI SKM 0.0003171 0.40516 13.0952
262 3DEF GDP 0.000004339 0.56588 13.4259
263 4WZ6 ATP 0.00001304 0.58953 13.7931
264 3AB3 GDP 0.00000002941 0.64068 13.8211
265 1F5N GNP 0.00001696 0.49585 13.8514
266 2O0J ADP 0.03307 0.40337 13.8889
267 2PEZ DAT 0.0007832 0.40369 13.9665
268 2PEZ GGZ 0.0007832 0.40369 13.9665
269 3QF7 ANP 0.0007925 0.45226 14
270 1JJ7 ADP 0.000000681 0.67774 14.3519
271 1TQ4 GDP 0.00000003684 0.63643 14.3519
272 3A4M ADP 0.00003157 0.56141 14.6154
273 1M7G AV2 0.000002663 0.60803 14.6919
274 1M7G ADP 0.0004101 0.4284 14.6919
275 1M7G ADX 0.0003638 0.41894 14.6919
276 5FII PHE 0.03778 0.40323 14.7059
277 5M04 GDP 0.0000000005646 0.79491 14.8148
278 1APZ ASP 0.007677 0.43678 14.8936
279 2XTN GTP 0.000001879 0.55005 14.9573
280 3IIJ ADP 0.0000564 0.53341 15
281 4QM7 GTP 0.00006677 0.52977 15.2047
282 5I0H ADP BEF 0.0000003346 0.59478 15.2778
283 2VF7 ADP 0.0002158 0.49844 15.6164
284 4DCT GDP 0.000000003311 0.73167 15.7407
285 3ZS9 ADP ALF 0.00005283 0.47636 15.7895
286 3PQC GDP 0.00000009965 0.65064 15.8974
287 1BG2 ADP 0.000002107 0.64019 16
288 1G8S MET 0.01209 0.42921 16.087
289 1XXR MAN 0.03041 0.40698 16.1491
290 1SQ5 ADP 0.0003618 0.48756 16.2037
291 2FH5 GTP 0.00000000001043 0.79064 16.2162
292 2HCJ GDP 0.000000001369 0.77534 16.2162
293 2V7Q ATP 0.00006531 0.5173 16.6667
294 2V7Q ADP 0.0002554 0.50086 16.6667
295 3T12 GDP ALF 0.0000000007053 0.70193 16.9118
296 4OI4 ATP 0.002208 0.42178 17.3913
297 1VHT BA3 0.002005 0.44688 17.8899
298 4R98 GNH 0.0000008545 0.6237 18.0812
299 1B0U ATP 0.0007038 0.46355 18.5185
300 4ZG4 VO4 ADP 0.0000009413 0.5626 18.9815
301 5HR5 ADP 0.0005466 0.46391 19.4444
302 1FQK ALF 0.0000001066 0.70652 19.7279
303 1FQK GDP 0.00000004945 0.61606 19.7279
304 1W7J ADP BEF 0.000008537 0.54575 19.9074
305 1KSH GDP 0.0000000000539 0.75963 20.9677
306 2KIN ADP 0.000003164 0.62919 21
307 1GP2 GDP 0.0000007607 0.56646 21.1268
308 2PL3 ADP 0.0006989 0.48497 21.1864
309 4M9Q GNP 0.00000000004692 0.75208 21.2963
310 1MR3 G3D 0.000000003807 0.72873 21.547
311 1F6B GDP 0.00000000895 0.71075 21.7172
312 1D2E GDP 0.0000001562 0.63271 21.7593
313 1G6O ADP 0.0001483 0.50044 21.8182
314 1RE0 GDP 0.000000001024 0.78176 22.561
315 1S9D GDP 0.00000001267 0.70344 22.561
316 1MKY GDP 0.00000000294 0.74593 22.6852
317 2A5F GTP 0.0000000001291 0.71499 22.8571
318 1J2J GTP 0.000000000004026 0.7869 22.8916
319 1O3Y GTP 0.00000000001102 0.76862 22.8916
320 1GOT GDP 0.0000002953 0.59024 23.2877
321 1UPT GTP 0.000000000006977 0.78734 23.3333
322 2WIC GNP 0.00000002166 0.69216 23.6111
323 5L3R GCP 0.000006599 0.52199 23.6111
324 1FQJ ALF 0.00000006381 0.71068 23.8095
325 1FQJ GDP 0.00000002266 0.63021 23.8095
326 4R2I ANP 0.0003421 0.50738 24.2857
327 1LOB MMA 0.03653 0.40247 25
328 1GXU 2HP 0.001431 0.46176 25.2747
329 3A1S GDP 0.0000003438 0.63398 26.3889
330 3ZIA ATP 0.000163 0.50434 26.9841
331 3ZIA ADP 0.0002682 0.48295 26.9841
332 1M2O GNP 0.000000001047 0.66978 27.3684
333 2GJ8 ALF GDP 0.000000002671 0.64606 28.4884
334 1FZQ GDP 0.0000000008984 0.77148 28.7293
335 2QTV GNP 0.0000000002085 0.70645 28.7425
336 1YZG GDP 0.0000000108 0.70679 29.0503
337 2J0V GDP 0.000000002551 0.73716 29.2453
338 2WKQ GTP 0.0000000000004939 0.82497 29.6296
339 5KDO GDP 0.0000004633 0.58864 29.7297
340 1ZJ6 G3D 0.000000005409 0.72134 29.9465
341 3REF GDP 0.000000001625 0.68649 30.4124
342 4BAS GNP 0.000000001048 0.69461 31.1558
343 2GCO GNP 0.000000000027 0.79492 31.3433
344 2GCN GDP 0.000000002 0.68265 31.3433
345 1GWN GTP 0.00000000002579 0.77354 31.7073
346 1RYH GNP 0.00000000001067 0.83861 32.0197
347 1XTQ GDP 0.0000000002508 0.71193 32.2034
348 1IK4 PGH 0.008004 0.42233 32.2368
349 2D7D ADP 0.001938 0.45718 32.5
350 1DS6 GDP 0.0000000008302 0.77318 32.8125
351 1I4D GDP 0.000000001543 0.77269 33.3333
352 2W2X GSP 0.000000000008755 0.79393 33.5135
353 1OW3 GDP 0.0000000005202 0.73672 33.6788
354 4V0K GDP 0.0000007298 0.56118 33.7278
355 3SBD GNP 0.0000000000002014 0.81927 34.2246
356 1A4R GNH 0.0000000004894 0.73792 34.555
357 1A4R GDP 0.0000000006584 0.722 34.555
358 4D0N GDP 0.000000003815 0.74032 34.5946
359 1CXZ GSP 0.000000000003121 0.80222 34.6154
360 4DID GDP 0.000000002307 0.73927 34.715
361 1NF3 GNP 0.000000000001082 0.78989 34.8718
362 1E96 GTP 0.00000000000002187 0.85805 34.8958
363 2NGR GDP 0.00000000006758 0.81355 35.0785
364 1GRN GDP 0.0000000001446 0.76191 35.0785
365 2NGR AF3 0.000000006769 0.75293 35.0785
366 1GRN AF3 0.00000001158 0.74075 35.0785
367 4ITR GDP 0.0000000383 0.64372 35.0785
368 5HPY GDP 0.0000000005916 0.73419 35.1351
369 1M7B GTP 0.00000000003714 0.76666 35.3261
370 1G4U GDP 0.00000003402 0.646 35.3261
371 1G4U AF3 0.000003691 0.6235 35.3261
372 2FJU GSP 0.0000000000008376 0.83823 35.9551
373 2OM2 GDP 0.0000006221 0.58308 36.1111
374 3T5G GDP 0.0000000009464 0.57461 36.4641
375 1MH1 GNP 0.00000000001032 0.74137 36.5591
376 5IRC GDP 0.000000001423 0.738 36.5591
377 1TX4 ALF GDP 0.000000000007955 0.77454 36.7232
378 1KMQ GNP 0.0000000000007677 0.81696 37.5
379 1HE1 GDP 0.000000008517 0.66407 37.5
380 1HE1 AF3 0.000001328 0.63325 37.5
381 1Y3A GDP 0.0000001011 0.60309 37.5
382 1R4A GNP 0.000000000144 0.71305 38.1818
383 1ZD9 GDP 0.00000000004403 0.77412 38.8298
384 2G77 GDP 0.0000000006713 0.7317 39.899
385 2G77 AF3 0.0000001599 0.69007 39.899
386 2BCG GDP 0.0000000006285 0.7229 41.7476
387 4DSU GDP 0.00000000002575 0.72569 41.7989
388 2ZEJ GDP 0.000001078 0.54313 41.8478
389 2F9L GDP 0.000000001799 0.67618 42.2111
390 1OIV GDP 0.0000000009811 0.67091 42.4084
391 1OIX GDP 0.0000000000004692 0.80449 42.9319
392 2CJW GDP 0.0000000001198 0.81491 43.2292
393 5TB5 GDP 0.0000000001678 0.78195 43.2432
394 5TAR GDP 0.0000000002352 0.76337 43.2432
395 4U5X GNP 0.00000000009267 0.75978 43.2584
396 5UQW GDP 0.00000000005006 0.73185 43.3862
397 2A9K GDP 0.0000000001731 0.75837 44.385
398 1Z06 GNP 0.00000000000101 0.80133 44.9735
399 3Q85 GNP 0.0000000003169 0.79394 45.5621
400 1VG8 GNP 0.00000000000007172 0.82661 45.8937
401 1VG0 GDP 0.0000000001207 0.77679 45.8937
402 3BC1 GNP 0.000000000000166 0.82264 46.1538
403 5XCO GDP 0.00000000004589 0.79623 46.1988
404 1YZN GNP 0.00000000000003386 0.83948 46.4865
405 2A5J GDP 0.0000000000762 0.79818 46.5969
406 1X1R GDP 0.0000000001864 0.69173 46.6292
407 4K81 GTP 0.0000000000001106 0.80163 46.7836
408 2C5L GTP 0.00000000000001354 0.85518 46.8208
409 3Q72 GNP 0.0000000001426 0.8253 46.988
410 5O2T GSP 0.00000000000002998 0.8416 47.3373
411 3RWO GDP 0.0000000002497 0.69482 47.5676
412 5UFQ GNP 0.0000000001439 0.70445 47.5904
413 2HV8 GTP 0.000000000005628 0.76108 47.6744
414 4C4P GNP 0.000000000002158 0.76822 47.9769
415 1ZC3 GNP 0.0000000000006989 0.78756 48
416 2UZI GTP 0.00000000000003342 0.85067 48.1928
417 1NVU GTP 0.00000000000002509 0.84461 48.1928
418 1CLU DBG 0.0000000004194 0.54489 48.1928
419 1G16 GDP 0.0000000009646 0.69614 48.2353
420 2HT6 GDP 0.00000000009126 0.83517 48.2759
421 1LFD GNP 0.00000000000002498 0.85571 48.503
422 2D7C GTP 0.000000000004235 0.76605 48.503
423 1NVV GNP 0.00000000000000544 0.87097 48.7952
424 3KUD GDP 0.0000000000003688 0.85371 48.7952
425 1WQ1 GDP 0.000000000007038 0.77676 48.7952
426 1WQ1 AF3 0.00000001121 0.76073 48.7952
427 1U8Z GDP 0.0000000001269 0.72429 48.8095
428 1KY3 GDP 0.0000000002688 0.76069 48.9011
429 1YVD GNP 0.0000000000005383 0.80209 49.1124
430 3DDC GNP 0.000000000000006217 0.86855 49.3976
431 2FFQ GSP 0.0000000000002865 0.80285 49.7076
432 1Z0F GDP 0.00000000007288 0.81196 49.7207
433 3QBT GNP 0.00000000000007472 0.83658 50
434 1Z0J GTP 0.0000000000002708 0.80382 50
435 1Z0A GDP 0.00000000009814 0.79298 50
Pocket No.: 2; Query (leader) PDB : 3GJX; Ligand: GTP; Similar sites found: 11
This union binding pocket(no: 2) in the query (biounit: 3gjx.bio2) has 27 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4B2D FBP 0.01524 0.40158 4.0146
2 1P4V GLY 0.01218 0.42737 6.1017
3 3BP1 GUN 0.01806 0.41788 6.94444
4 4UOX PUT 0.01468 0.40234 6.94444
5 4U60 SIA GAL NGA 0.02 0.41235 7.5
6 1CT9 GLN 0.03204 0.40012 8.31826
7 4OUE IPT 0.04314 0.40062 10.0213
8 2UVO NDG 0.04042 0.4061 12.8655
9 5O0X FAD 0.0255 0.40138 13.4259
10 4PU6 ASP 0.008367 0.43482 16.0305
11 5J6H NCA 0.01465 0.40268 20
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