-->
Receptor
PDB id Resolution Class Description Source Keywords
3GWZ 1.91 Å NON-ENZYME: OTHER STRUCTURE OF THE MITOMYCIN 7-O-METHYLTRANSFERASE MMCR STREPTOMYCES LAVENDULAE METHYLTRANSFERASE MITOMYCIN MMCR S-ADENOSYL METHIONINE TRANSFERASE
Ref.: STRUCTURAL CHARACTERIZATION OF THE MITOMYCIN 7-O-METHYLTRANSFERASE. PROTEINS V. 79 2181 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CA A:350;
D:350;
D:351;
D:352;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
40.078 Ca [Ca+2...
MPD A:351;
B:350;
C:350;
D:353;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
118.174 C6 H14 O2 C[C@@...
SAH A:352;
B:351;
C:351;
D:354;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3GWZ 1.91 Å NON-ENZYME: OTHER STRUCTURE OF THE MITOMYCIN 7-O-METHYLTRANSFERASE MMCR STREPTOMYCES LAVENDULAE METHYLTRANSFERASE MITOMYCIN MMCR S-ADENOSYL METHIONINE TRANSFERASE
Ref.: STRUCTURAL CHARACTERIZATION OF THE MITOMYCIN 7-O-METHYLTRANSFERASE. PROTEINS V. 79 2181 2011
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 3GWZ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 3GWZ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 3GWZ - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3GWZ; Ligand: SAH; Similar sites found with APoc: 477
This union binding pocket(no: 1) in the query (biounit: 3gwz.bio2) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 1FUT 2GP None
2 5X62 SAH 0.813008
3 1ORR NAD 0.864553
4 1G0N PHH 1.06007
5 1G0N NDP 1.06007
6 1G55 SAH 1.16618
7 4NBU NAI 1.2
8 2PT9 S4M 1.24611
9 2PT9 2MH 1.24611
10 4UCI SAM 1.35501
11 5BVA FAD 1.35501
12 2I7C AAT 1.41343
13 1UDB NAD 1.47929
14 1UDB UFG 1.47929
15 4GLL NAD 1.48368
16 1GEG NAD 1.5625
17 2YY7 NAD 1.60256
18 3NDJ JHZ 1.62602
19 3NDJ SAH 1.62602
20 1GY8 NAD 1.62602
21 1R6D NAD 1.62602
22 1R6D DAU 1.62602
23 1I8T FAD 1.63488
24 1EDO NAP 1.63934
25 2O07 SPD 1.64474
26 2O07 MTA 1.64474
27 3TKA SAM 1.72911
28 2DPM SAM 1.76056
29 4POW OP1 1.88679
30 3NTD FAD 1.89702
31 4LWP SAH 1.90217
32 4MO2 FDA 1.90217
33 4MO2 FAD 1.90217
34 3KO8 NAD 1.92308
35 4FN4 NAD 1.9685
36 1JQ3 AAT 2.02703
37 3S1S SAH 2.16802
38 5WGR FAD 2.16802
39 1VDC FAD 2.16802
40 1PN0 FAD 2.16802
41 1PN0 IPH 2.16802
42 3NT6 FAD 2.26481
43 3NTA FAD 2.26481
44 2P41 SAH 2.29508
45 1YXM ADE 2.31023
46 1ZX5 LFR 2.33333
47 1FK8 NAD 2.33463
48 3GEG NAD 2.42915
49 5MPT SAH 2.43902
50 5DNK SAH 2.43902
51 6D6Y SAH 2.43902
52 1U2Z SAH 2.43902
53 4BUZ OAD 2.43902
54 4BUZ OCZ 2.43902
55 4BUZ NAD 2.43902
56 5VN0 FAD 2.43902
57 5VN0 NAI 2.43902
58 1YC5 NCA 2.43902
59 1RLZ NAD 2.43902
60 1X87 NAD 2.43902
61 3ICT FAD 2.43902
62 3ICS FAD 2.43902
63 1QAN SAH 2.45902
64 4G5H NAP 2.47934
65 4G5H UD7 2.47934
66 5XLX SAH 2.48227
67 5YF1 8V0 2.48619
68 5YF1 SFG 2.48619
69 3EVG SAH 2.54545
70 1JA9 NDP 2.55474
71 5E9W SAH 2.5641
72 5EJ2 NAD 2.5974
73 2AE2 NAP 2.69231
74 2AE2 PTO 2.69231
75 4GQB 0XU 2.71003
76 4X60 SFG 2.71003
77 4X60 3XV 2.71003
78 1UWK URO 2.71003
79 1UWK NAD 2.71003
80 5FA5 MTA 2.71003
81 4RPL 3UC 2.71003
82 4RPL FAD 2.71003
83 3Q9T FAY 2.71003
84 5OC1 FAD 2.71003
85 2DTX BMA 2.71003
86 3FRH SAH 2.7668
87 3OFK SAH 2.77778
88 1ZK4 NAP 2.78884
89 1ZK4 AC0 2.78884
90 3LCV SAM 2.84698
91 4FC7 COA 2.88809
92 4FC7 NAP 2.88809
93 6EQS BV8 2.90909
94 1JJV ATP 2.91262
95 3RIY NAD 2.9304
96 4RF2 NAP 2.94118
97 2WPB ZZI 2.96053
98 4ITU NAI 2.97398
99 4ITU 1HS 2.97398
100 5WP5 SAH 2.98103
101 1JG3 ADN 2.98103
102 4YNU FAD 2.98103
103 4YNU LGC 2.98103
104 6CI9 NAP 2.98103
105 1IY8 NAD 2.98103
106 2C31 ADP 2.98103
107 2C31 TZD 2.98103
108 3G5S FAD 2.98103
109 4LHD GLY 2.98103
110 3V1U NAD 2.98103
111 1VL8 NAP 2.99625
112 4POO SAM 3
113 5OVL NAP 3
114 5OJI ISN 3.07692
115 5OJI NAP 3.07692
116 3OID NDP 3.10078
117 5WUW NAP 3.13589
118 2WSB NAD 3.14961
119 4CNO 9PY 3.1746
120 2CFC NAD 3.2
121 1ZK7 FAD 3.21199
122 6BQ6 TER 3.25203
123 6BWL NAD 3.25203
124 2NXE SAM 3.25203
125 2WA2 SAM 3.26087
126 2BD0 NAP 3.27869
127 4O67 1SY 3.30579
128 1RKX NAD 3.36134
129 3LCC SAH 3.40426
130 4TQG NDP 3.40557
131 3RKR NAP 3.43511
132 2XYQ SAH 3.44828
133 1SQF SAM 3.4965
134 4M37 SAH 3.49854
135 4M38 SAH 3.49854
136 4NBW NAD 3.50195
137 5FTW SAH 3.51562
138 4N49 SAM 3.52304
139 5OOH NAP 3.52304
140 5OOH 9ZZ 3.52304
141 4HA6 FAD 3.52304
142 2IHK CSF 3.52304
143 1V59 FAD 3.52304
144 2HQM FAD 3.52304
145 3NUG NAD 3.52304
146 4V3C C 3.52304
147 1S7G APR 3.55731
148 1S7G NAD 3.55731
149 1LSS NAD 3.57143
150 3SJ7 NDP 3.57143
151 2BGM NAJ 3.59712
152 4Y9D NAI 3.60656
153 2EWM NAD 3.61446
154 1MXH DHF 3.62319
155 1MXH NAP 3.62319
156 1N2X SAM 3.65448
157 2CIG 1DG 3.77358
158 5KOK S9T 3.79404
159 5KOK R9T 3.79404
160 5KOK SAH 3.79404
161 3U31 NAD 3.79404
162 5HSA FAS 3.79404
163 2RAB FAD 3.79404
164 4M52 FAD 3.79404
165 2A14 SAH 3.80228
166 1XCL SAH 3.82979
167 5W7M SAH 3.84615
168 1G60 SAM 3.84615
169 3CH6 NAP 3.84615
170 3CH6 311 3.84615
171 1NFQ NAI 3.84615
172 2BZG SAH 3.87931
173 1WVG APR 3.89972
174 1R18 SAH 3.96476
175 5FUB SAH 4.06504
176 1FEC FAD 4.06504
177 3HDY GDU 4.06504
178 3HDY FDA 4.06504
179 3PT9 SAH 4.06504
180 4IEE AGS 4.06504
181 3HDY FAD 4.06504
182 3T7S SAM 4.10448
183 3MQ2 SAH 4.12844
184 5JGL SAM 4.15225
185 4GKV NAD 4.16667
186 5GT9 NAP 4.18251
187 6FDF SAH 4.19162
188 5DY5 5GR 4.27632
189 5WP4 SAH 4.27699
190 2RH4 EMO 4.33213
191 2ZWA SAH 4.33604
192 6F97 FAD 4.33604
193 4ONQ SFG 4.33604
194 4ZA2 NAD 4.34783
195 2ZIF SAM 4.3771
196 3A4T SFG 4.37956
197 3O7W SAM 4.42177
198 1I1N SAH 4.42478
199 4URF NAD 4.43548
200 5ULP KB1 4.47761
201 1P1C SAH 4.52261
202 3DXY SAM 4.58716
203 3BXO SAM 4.60705
204 5ERG SAM 4.60705
205 5K7U SAM 4.60705
206 2FK8 SAM 4.60705
207 3EYA FAD 4.60705
208 3GCZ SAM 4.60993
209 3K1X DBX 4.61538
210 1Q0S SAH 4.6332
211 4R6W PC 4.65116
212 4R6W SAH 4.65116
213 5MGZ SAH 4.66102
214 3ELW SAM 4.66667
215 3ELW GP3 4.66667
216 3LU1 NAD 4.67033
217 1BXK NAD 4.78873
218 1SB8 UD2 4.82955
219 1SB8 NAD 4.82955
220 1WY7 SAH 4.83092
221 2OBF F83 4.84429
222 2OBF SAH 4.84429
223 2GDZ NAD 4.86891
224 2VDV SAM 4.87805
225 4YUW 4JU 4.87805
226 4YUW S4M 4.87805
227 2ZXI FAD 4.87805
228 1L1E SAH 4.87805
229 5DLY SAH 4.88722
230 5DLY 5D7 4.88722
231 2GN4 NDP 4.94186
232 2GN4 UD1 4.94186
233 1UAY ADN 4.95868
234 1E3W NAD 4.98084
235 1E6W NAD 5
236 2EJU SAH 5.02645
237 2PWY SAH 5.03876
238 3G89 SAM 5.14905
239 1BZL FAD 5.14905
240 1BZL GCG 5.14905
241 6GFK SAH 5.14905
242 1PVN MZP 5.14905
243 6B92 SAH 5.14905
244 2JJQ SAH 5.14905
245 4QTU SAM 5.18518
246 5E72 SAM 5.20231
247 2PX8 SAH 5.20446
248 1KPG SAH 5.22648
249 1KPH SAH 5.22648
250 1O97 AMP 5.30303
251 1O97 FAD 5.30303
252 3WMX NAD 5.30726
253 5HJM MTA 5.39773
254 3EVF GTA 5.41516
255 3EVF SAH 5.41516
256 4KRG SAH 5.42005
257 3TLJ SAH 5.42005
258 5U19 827 5.42005
259 5U19 SAH 5.42005
260 2EFJ SAH 5.46875
261 1EFV FAD 5.4902
262 1EFV AMP 5.4902
263 1EJ0 SAM 5.55556
264 2ZFU SAH 5.5814
265 1O5I NAD 5.62249
266 5D9X GSH 5.65217
267 5IL1 SAM 5.66667
268 6C8R EQV 5.69106
269 6C8R SAH 5.69106
270 3SSO SAH 5.69106
271 5T2U NAP 5.69106
272 2Q1W NAD 5.70571
273 4YAC NAI 5.72391
274 1ZEM NAD 5.72519
275 5K0A FAD 5.75758
276 4ZRN NAD 5.76923
277 4ZRN UPG 5.76923
278 4K26 SFF 5.7971
279 4K26 NDP 5.7971
280 5Z75 NAD 5.8104
281 5FFF 5XC 5.83658
282 5FFF NAP 5.83658
283 2NU8 COA 5.90278
284 3LKZ SFG 5.919
285 5J60 FAD 5.9375
286 2EG5 SAH 5.96206
287 3QOX SAH 5.96206
288 4EUE NAI 5.96206
289 4DCM SAM 5.96206
290 3C6K SPD 5.96206
291 2Q28 ADP 5.96206
292 3C6K MTA 5.96206
293 3LAD FAD 5.96206
294 3K7M FAD 5.96206
295 5Y1G NAD 6.09756
296 5Y1G AKB 6.09756
297 4IWN GEK 6.11354
298 1FFU CDP 6.13497
299 5U8U FAD 6.23306
300 1Y8Q ATP 6.23306
301 4YMH SAH 6.25
302 6GKV SAH 6.26781
303 4MDH NAD 6.28743
304 2PZM NAD 6.36364
305 2PZM UDP 6.36364
306 1XHL NDP 6.39731
307 4FZV SAM 6.40669
308 3GRU AMP 6.44068
309 5JE0 AZ8 6.47773
310 5JE0 SAH 6.47773
311 4PIO AVI 6.50155
312 4PIO SAH 6.50155
313 3A4V PYR 6.50407
314 3A4V NAD 6.50407
315 3O03 NAP 6.52921
316 5FEU NAP 6.52921
317 5O42 NAD 6.56934
318 5O42 9JW 6.56934
319 5O42 BGC 6.56934
320 5MW4 5JU 6.58683
321 6HOY AR6 6.62252
322 6HOY TSN 6.62252
323 3QWI NAP 6.66667
324 3QWI CUE 6.66667
325 5YJI SAH 6.69014
326 5YJI 8WO 6.69014
327 2WK1 SAH 6.73759
328 1U0J ADP 6.74157
329 3ZG6 APR 6.75676
330 5FWA J7C 6.77507
331 5YS9 FAD 6.77507
332 2FR1 NDP 6.77507
333 5E8J SAH 6.81818
334 1NW5 SAM 6.89655
335 3MB5 SAM 7.04607
336 3ITJ FAD 7.04607
337 1Z3C SA8 7.04698
338 3VC1 GST 7.05128
339 3VC1 SAH 7.05128
340 3U4C NDP 7.11744
341 4X7Y SAH 7.29927
342 5NA1 FAD 7.35294
343 3TN7 NJP 7.393
344 1XSE NDP 7.45763
345 3ZV6 4HB 7.47331
346 3ZV6 NAD 7.47331
347 4NEC SAH 7.57576
348 4PNE SAH 7.58808
349 5BW4 SAM 7.58808
350 3I6I NDP 7.80347
351 3X0D SAH 7.85908
352 6B3A SAM 7.85908
353 5XNC MTA 7.85908
354 3SJU NDP 7.8853
355 2JAH NDP 8.09717
356 2JAP NDP 8.09717
357 5GWX SAR 8.09859
358 5GWX SAM 8.09859
359 6ECT SAM 8.09969
360 4RVG SAM 8.13008
361 4RVG TYD 8.13008
362 5Z2L NDP 8.16327
363 5DM1 SAH 8.2397
364 5DM1 5D7 8.2397
365 3GDH SAH 8.29876
366 1BDB NAD 8.30325
367 3PFG SAM 8.36502
368 3PFG TLO 8.36502
369 2GMH FAD 8.40108
370 2CDU FAD 8.40108
371 1F3L SAH 8.41121
372 3GD4 FAD 8.41487
373 3GD4 NAD 8.41487
374 3FZG SAM 8.5
375 3A28 NAD 8.52713
376 5JJR SAH 8.67209
377 5JAQ NAI 8.67209
378 1JV1 UD1 8.67209
379 4C4A SAH 8.94309
380 6DUB SAH 9.00901
381 2XT3 ADP 9.01163
382 2DKN NAI 9.01961
383 1NV8 MEQ 9.15493
384 1NV8 SAM 9.15493
385 6ECU SAH 9.17722
386 6ECW SAH 9.20635
387 2ZWI C5P 9.21409
388 1YBH FAD 9.21409
389 5ZW3 SAH 9.33333
390 3H2B SAH 9.35961
391 4CQM NAP 9.42623
392 6ARJ BW4 9.45559
393 6ARJ SAH 9.45559
394 5DX0 SFG 9.45559
395 5DWQ SFG 9.45559
396 1U7T TDT 9.57854
397 1DL5 SAH 9.77918
398 1AE1 NAP 9.89011
399 1WG8 SAM 10.1754
400 4O0L NDP 10.1818
401 5YJF SAH 10.2113
402 5YJF 8WO 10.2113
403 3DMH GMP 10.2981
404 3DMH SAM 10.2981
405 1GPE FAD 10.2981
406 4BLW AMP 10.3806
407 4BLW SAH 10.3806
408 6F5Z SAH 10.3896
409 3OU2 SAH 10.5505
410 5F2K OCA 10.5978
411 5F2K SAH 10.5978
412 4KRI SAH 10.8401
413 1RJD SAM 11.0778
414 1TPY SAH 11.1111
415 3EGI ADP 11.165
416 4J1Q NDP 11.9241
417 5CUQ NSC 11.985
418 1JQD HSM 12.6712
419 2AOT SAH 12.6712
420 1JQD SAH 12.6712
421 5F8F SFG 13.0081
422 1XKQ NDP 13.0081
423 3WFD AXO 13.0137
424 3GU3 SAH 13.0282
425 4OBW SAM 13.2296
426 3BGD PM6 13.4615
427 3BGD SAH 13.4615
428 5M58 SAH 13.4783
429 5GM1 SAH 13.8047
430 3P2E SAH 14.2222
431 2HMT NAI 14.5833
432 5LOG SAH 14.5923
433 5T67 JHZ 14.6341
434 5T67 SAH 14.6341
435 2HNK SAH 14.6444
436 5FA8 SAM 14.9068
437 3KIF GDL 15.0943
438 4Y30 SAH 15.4472
439 4Y30 49L 15.4472
440 4NTD FAD 15.5882
441 3HVJ 705 16.2896
442 4XUC 43G 16.5138
443 4XUC SAM 16.5138
444 1I9G SAM 17.1429
445 3FUU ADN 17.7122
446 5BSZ SAH 18.4
447 5UFN SAH 18.4874
448 1IM8 SAI 19.2623
449 5E1M PRO PRO LYS ARG ILE ALA 20.7469
450 5E1M SAH 20.7469
451 1XTP SAI 23.2283
452 1BC5 SAH 24.1636
453 1L3I SAH 25
454 5DX8 SFG 26.3158
455 5DXA SFG 26.3158
456 5DX1 SFG 26.3158
457 3TKY SAH 27.3713
458 1KYZ FER 30.3523
459 1KYZ SAH 30.3523
460 4M73 SAH 30.8605
461 4M73 M72 30.8605
462 4KIB SAH 33.0532
463 1FP1 SAH 36.0434
464 1XDS SAM 36.3144
465 1QZZ SAM 37.1274
466 3P9C SAH 38.2114
467 4A6D SAM 38.5269
468 5ICE 2H4 41.4634
469 5ICE SAH 41.4634
470 1FP2 SAH 42.2764
471 1FP2 HMO 42.2764
472 1ZGA SAH 42.8184
473 3LST SAH 43.9655
474 5EEH SAH 46.0705
475 5EEH P9P 46.0705
476 3I53 SAH 46.988
477 4E70 N7I 47.4255
Pocket No.: 2; Query (leader) PDB : 3GWZ; Ligand: SAH; Similar sites found with APoc: 56
This union binding pocket(no: 2) in the query (biounit: 3gwz.bio2) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 1M2K APR 1.60643
2 4JDR FAD 1.62602
3 4TXJ THM 1.68919
4 1XHC FAD 1.90736
5 4Z24 FAD 2.16802
6 2NPX FAD 2.16802
7 2OG2 MLI 2.22841
8 2OD9 A1R NCA 2.27273
9 1SZD APR 2.3569
10 5WKC FAD 2.43902
11 6DEN TP9 2.43902
12 6DEN G8A 2.43902
13 6DEN FAD 2.43902
14 4I5I NAD 2.43902
15 3ICR FAD 2.43902
16 1T9D FAD 2.43902
17 5HW4 SAM 2.82258
18 5OJ7 AR6 3.14685
19 6H3O FAD 3.25203
20 3GDN FAD 3.25203
21 3ZRR PXG 3.25203
22 1LVL FAD 3.27511
23 3B9Q MLI 3.31126
24 3RNM FAD 3.52304
25 2RAB NAD 3.79404
26 2A8X FAD 3.79404
27 4TXI FAD 3.79404
28 1J0D 5PA 3.81232
29 5BO9 CSF 4.02477
30 1GET NAP 4.33604
31 1GET FAD 4.33604
32 2NVK FAD 4.33604
33 3DUW SAH 4.4843
34 4IQY AR6 4.58333
35 4D7E FAD 4.60705
36 2WPF FAD 4.87805
37 2WPF WPF 4.87805
38 1D4O NAP 4.8913
39 5EIN NAP 5.14905
40 3C3Y SAH 5.42005
41 4JSR 1NQ 5.61404
42 5KVA SAM 5.7554
43 2BEK ATP 5.83658
44 2OOR TXP 5.96206
45 4RSL FAD 6.50407
46 2Q7V FAD 6.77507
47 1OC2 TDX 6.89655
48 1OC2 NAD 6.89655
49 5N5D SAM 7.04607
50 3CBG SAH 7.32759
51 3HBN UDP 10.2837
52 1ZQ9 SAM 10.5263
53 3LXD FAD 11.3821
54 2F5Z FAD 15.625
55 4UP4 GAL NAG 20.3252
56 4KXQ APR 23.3333
Pocket No.: 3; Query (leader) PDB : 3GWZ; Ligand: SAH; Similar sites found with APoc: 32
This union binding pocket(no: 3) in the query (biounit: 3gwz.bio3) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 3VC3 C6P 1.45349
2 1GTE FAD 2.16802
3 2NPX NAD 2.16802
4 1H5Q NAP 2.26415
5 5K4W NAI 2.80374
6 3VZS NAP 3.11284
7 4EN4 GT0 3.20513
8 3GDN HBX 3.25203
9 6FP4 FAD 3.25203
10 4NBT NAD 3.33333
11 1EK6 UPG 3.44828
12 1EK6 NAI 3.44828
13 3E1T FAD 3.52304
14 4K5S PM0 3.52304
15 4K5S FAD 3.52304
16 4WHZ 3NL 3.63636
17 3QVP FAD 3.79404
18 4M52 M52 3.79404
19 5J5R IMP 3.85604
20 5J5R 6G1 3.85604
21 3RJ5 NAD 3.93701
22 1E6E FAD 4.6875
23 5OYH T99 5.18135
24 3OZ2 FAD 5.28967
25 1ZPT FAD 5.42005
26 3KV8 FAH 5.7554
27 4RIF 3R2 5.96206
28 1D4D FAD 6.46853
29 1PR9 NAP 6.96721
30 4J56 FAD 13.1579
31 3CXH SMA 15.3846
32 4UP4 NDG 20.3252
Pocket No.: 4; Query (leader) PDB : 3GWZ; Ligand: SAH; Similar sites found with APoc: 160
This union binding pocket(no: 4) in the query (biounit: 3gwz.bio3) has 19 residues
No: Leader PDB Ligand Sequence Similarity
1 3GCM 5GP 1.35501
2 4D5G FAD 1.62602
3 4D5G TPP 1.62602
4 3KLJ FAD 1.62602
5 5MLR NAP 1.62602
6 5MLR GRQ 1.62602
7 1H82 GZZ 1.62602
8 1H82 FAD 1.62602
9 3CGB FAD 1.62602
10 1GZ6 NAI 1.88088
11 5E5U MLT 1.89394
12 2YG3 FAD 1.89702
13 2AQJ TRP 1.89702
14 2AQJ FAD 1.89702
15 1YY5 FAD 2.16802
16 2V3V MGD 2.16802
17 1RSG FAD 2.16802
18 1REO FAD 2.16802
19 4YDD MD1 2.16802
20 4YDD MGD 2.16802
21 3PFD FDA 2.16802
22 6EL3 NAP 2.16802
23 5JWC FAD 2.16802
24 1KEW NAD 2.21607
25 2QQF A1R 2.27273
26 5F5N NAD 2.42215
27 1T9D 1MM 2.43902
28 1T9D PYD 2.43902
29 1T9D P25 2.43902
30 2IID PHE 2.43902
31 2IID FAD 2.43902
32 4USQ FAD 2.43902
33 4KGD FAD 2.43902
34 4KGD TDP 2.43902
35 1TMO 2MD 2.43902
36 5TS5 FAD 2.43902
37 6F7L FAD 2.48869
38 4A59 AMP 2.71003
39 4U8P FDA 2.71003
40 1U1I NAD 2.71003
41 4U8P UDP 2.71003
42 1E3I CXF 2.71003
43 5LOL GSH 2.7907
44 1RJW ETF 2.94985
45 4BWL MN9 2.96053
46 2Z3Y F2N 2.98103
47 1QO8 FAD 2.98103
48 2IVD FAD 2.98103
49 1E1M FAD 2.98103
50 1E1M NAP 2.98103
51 1Q9I TEO 2.98103
52 1Q9I FAD 2.98103
53 5BUK FAD 2.98103
54 1COY AND 3.25203
55 1COY FAD 3.25203
56 6FP4 E1T 3.25203
57 1YQZ FAD 3.25203
58 2V6G NAP 3.2967
59 1PNO NAP 3.33333
60 3WDM ADN 3.44828
61 3GF4 FAD 3.52304
62 3GF4 UPG 3.52304
63 1V59 NAD 3.52304
64 1RPN NDP 3.58209
65 1ZBQ NAD 3.66972
66 6F9Q NAD 3.67647
67 3AYI HCI 3.7448
68 3AYI FAD 3.7448
69 4YAG NAI 3.79404
70 1LLU NAD 3.80117
71 1MO9 FAD 4.06504
72 1MO9 KPC 4.06504
73 2GZ3 NAP 4.06504
74 4NTM 2K8 4.13223
75 4B63 ORN 4.33604
76 4B63 FAD 4.33604
77 4B63 NAP 4.33604
78 1R27 MGD 4.33604
79 5UAO FAD 4.33604
80 1DJL NAP 4.34783
81 1KQF MGD 4.42177
82 4EA7 JB2 4.54545
83 4EA7 COA 4.54545
84 2IV2 MGD 4.60705
85 3CTY FAD 4.60705
86 2WET FAD 4.87805
87 1NAA ABL 4.87805
88 1NAA 6FA 4.87805
89 2DKH FAD 4.87805
90 2DKH 3HB 4.87805
91 4YKG FAD 4.87805
92 4MIG G3F 4.87805
93 3GMB FAD 4.87805
94 5HXI 5HN 4.87805
95 2CVQ NDP 4.89297
96 5TTJ FAD 5.10204
97 2IVF MGD 5.14905
98 4X9M FAD 5.14905
99 3QFA FAD 5.14905
100 4C3Y FAD 5.14905
101 4C3Y ANB 5.14905
102 1DMR PGD 5.42005
103 2VT3 ATP 5.5814
104 1H0H MGD 5.60748
105 1H0H 2MD 5.60748
106 1EU1 MGD 5.69106
107 5J5Z FAD 5.69106
108 1TUU AMP 5.69106
109 4YSX FAD 5.76923
110 1FL2 FAD 5.80645
111 5BRT CH9 5.96206
112 5BRT FAD 5.96206
113 5MIT FAD 6.11621
114 5MIT NAP 6.11621
115 2VPY MGD 6.15385
116 1V5F FAD 6.23306
117 1V5F TPP 6.23306
118 5KOX RFP 6.23306
119 5KOX FAD 6.23306
120 2VVL FAD 6.23306
121 2VVM FAD 6.23306
122 2Q0L FAD 6.23306
123 5MDH NAD 6.30631
124 2GAG FAD 6.50407
125 2GAG FOA 6.50407
126 1JNR FAD 6.50407
127 1ELI PYC 6.50407
128 2GAG NAD 6.50407
129 3H8V ATP 6.50685
130 1NM5 NAP 6.77083
131 1NM5 NAD 6.77083
132 5TWB FAD 6.97674
133 2JB2 PHE 7.31707
134 2JB2 FAD 7.31707
135 5ZYN FAD 7.31707
136 1R37 NAD 7.4928
137 3AD8 FAD 7.58808
138 3AD8 PYC 7.58808
139 3S5W FAD 7.58808
140 1DUG GSH 7.69231
141 5THQ NDP 7.72059
142 1AOE GW3 7.8125
143 1AOE NDP 7.8125
144 2Z4T C5P 8.13008
145 5OCG 9R5 8.46561
146 2CUL FAD 8.62069
147 2C7G FAD 9.21053
148 2C7G ODP 9.21053
149 6FA4 D1W 9.24856
150 4AT0 FAD 9.4851
151 3ML1 MGD 9.62963
152 4CNK FAD 10.2981
153 4GUT FAD 10.5691
154 4HSU FAD 10.5691
155 4GUS FAD 10.5691
156 4BV6 FAD 11.1111
157 1G8K MGD 12.4661
158 1TL2 NDG 15.2542
159 5L95 AMP 16.25
160 4II2 ATP 20.4819
Pocket No.: 5; Query (leader) PDB : 3GWZ; Ligand: SAH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 3gwz.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 3GWZ; Ligand: SAH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 3gwz.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 3GWZ; Ligand: SAH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 3gwz.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 8; Query (leader) PDB : 3GWZ; Ligand: SAH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 3gwz.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback