Receptor
PDB id Resolution Class Description Source Keywords
3HQR 2 Å EC: 1.14.11.- PHD2:MN:NOG:HIF1-ALPHA SUBSTRATE COMPLEX HOMO SAPIENS DOUBLE STRANDED BETA-HELIX ALTERNATIVE SPLICING CONGENITALERYTHROCYTOSIS DIOXYGENASE DISEASE MUTATION IRON METAL-OXIDOREDUCTASE VITAMIN C ZINC ZINC-FINGER ACTIVATOR CYDNA-BINDING HYDROXYLATION ISOPEPTIDE BOND NUCLEUS PHOSPHOPROTEIN POLYMORPHISM S-NITROSYLATION TRANSCRIPTIOTRANSCRIPTION REGULATION UBL CONJUGATION OXIDOREDUCTASE- TRANSCRIPTION COMPLEX
Ref.: STRUCTURAL BASIS FOR BINDING OF HYPOXIA-INDUCIBLE F THE OXYGEN-SENSING PROLYL HYDROXYLASES STRUCTURE V. 17 981 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MN A:501;
Part of Protein;
none;
submit data
54.938 Mn [Mn+2...
OGA A:600;
Valid;
none;
submit data
147.086 C4 H5 N O5 C(C(=...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3HQR 2 Å EC: 1.14.11.- PHD2:MN:NOG:HIF1-ALPHA SUBSTRATE COMPLEX HOMO SAPIENS DOUBLE STRANDED BETA-HELIX ALTERNATIVE SPLICING CONGENITALERYTHROCYTOSIS DIOXYGENASE DISEASE MUTATION IRON METAL-OXIDOREDUCTASE VITAMIN C ZINC ZINC-FINGER ACTIVATOR CYDNA-BINDING HYDROXYLATION ISOPEPTIDE BOND NUCLEUS PHOSPHOPROTEIN POLYMORPHISM S-NITROSYLATION TRANSCRIPTIOTRANSCRIPTION REGULATION UBL CONJUGATION OXIDOREDUCTASE- TRANSCRIPTION COMPLEX
Ref.: STRUCTURAL BASIS FOR BINDING OF HYPOXIA-INDUCIBLE F THE OXYGEN-SENSING PROLYL HYDROXYLASES STRUCTURE V. 17 981 2009
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 31 families.
1 3HQU - UN9 C12 H9 Cl N2 O4 c1ccc2c(c1....
2 3HQR - OGA C4 H5 N O5 C(C(=O)O)N....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 5L9B - AKG C5 H6 O5 C(CC(=O)O)....
2 3HQU - UN9 C12 H9 Cl N2 O4 c1ccc2c(c1....
3 3HQR - OGA C4 H5 N O5 C(C(=O)O)N....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 5L9B - AKG C5 H6 O5 C(CC(=O)O)....
2 3HQU - UN9 C12 H9 Cl N2 O4 c1ccc2c(c1....
3 3HQR - OGA C4 H5 N O5 C(C(=O)O)N....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: OGA; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 OGA 1 1
2 AAC 0.461538 0.827586
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3HQR; Ligand: OGA; Similar sites found with APoc: 1
This union binding pocket(no: 1) in the query (biounit: 3hqr.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 4J25 OGA 38.8646
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