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Receptor
PDB id Resolution Class Description Source Keywords
3KN5 2.4 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF THE C-TERMINAL KINASE DOMAIN OF MSK1 IN WITH AMP-PNP HOMO SAPIENS KINASE AMP-PNP MSK1 MSK ATP-BINDING METAL-BINDING NUCLBINDING SERINE/THREONINE-PROTEIN KINASE TRANSFERASE
Ref.: THE CRYSTAL STRUCTURE OF THE ACTIVE FORM OF THE C-T KINASE DOMAIN OF MITOGEN- AND STRESS-ACTIVATED PROT KINASE 1. J.MOL.BIOL. V. 399 41 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ANP A:400;
B:400;
Valid;
Valid;
none;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3KN5 2.4 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF THE C-TERMINAL KINASE DOMAIN OF MSK1 IN WITH AMP-PNP HOMO SAPIENS KINASE AMP-PNP MSK1 MSK ATP-BINDING METAL-BINDING NUCLBINDING SERINE/THREONINE-PROTEIN KINASE TRANSFERASE
Ref.: THE CRYSTAL STRUCTURE OF THE ACTIVE FORM OF THE C-T KINASE DOMAIN OF MITOGEN- AND STRESS-ACTIVATED PROT KINASE 1. J.MOL.BIOL. V. 399 41 2010
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 117 families.
1 3KN5 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 91 families.
1 3KN5 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 60 families.
1 3KN5 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 373
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 AP5 0.802632 0.945205
5 ADP 0.802632 0.972222
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 HEJ 0.772152 0.972222
9 ATP 0.772152 0.972222
10 AT4 0.769231 0.933333
11 AN2 0.769231 0.986111
12 5FA 0.7625 0.972222
13 AQP 0.7625 0.972222
14 M33 0.759494 0.932432
15 MAP 0.752941 0.972973
16 ACP 0.75 0.945946
17 AR6 0.740741 0.945205
18 APR 0.740741 0.945205
19 ACQ 0.73494 0.945946
20 AD9 0.731707 0.945946
21 SAP 0.731707 0.921053
22 AGS 0.731707 0.921053
23 A 0.723684 0.944444
24 AMP 0.723684 0.944444
25 ATF 0.717647 0.933333
26 ADX 0.716049 0.851852
27 CA0 0.716049 0.92
28 6YZ 0.709302 0.945946
29 50T 0.707317 0.932432
30 PRX 0.698795 0.87013
31 ABM 0.696203 0.893333
32 AP2 0.679012 0.933333
33 A12 0.679012 0.933333
34 APC 0.678571 0.933333
35 T99 0.674419 0.933333
36 TAT 0.674419 0.933333
37 A22 0.674157 0.958904
38 SRA 0.670886 0.894737
39 SRP 0.670455 0.883117
40 5AL 0.666667 0.906667
41 A1R 0.659341 0.884615
42 ADQ 0.659341 0.92
43 A3R 0.659341 0.884615
44 3OD 0.648936 0.92
45 BIS 0.648936 0.909091
46 5SV 0.648352 0.82716
47 9X8 0.645161 0.896104
48 OAD 0.645161 0.92
49 25L 0.642105 0.958904
50 AMO 0.641304 0.907895
51 G5P 0.636364 0.897436
52 DLL 0.634409 0.906667
53 AHX 0.634409 0.897436
54 00A 0.634409 0.860759
55 ADV 0.632184 0.907895
56 RBY 0.632184 0.907895
57 ADP PO3 0.632184 0.917808
58 NB8 0.631579 0.897436
59 25A 0.630435 0.945205
60 OOB 0.630435 0.906667
61 8QN 0.630435 0.906667
62 G3A 0.626263 0.897436
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 TXA 0.614583 0.907895
67 1ZZ 0.614583 0.819277
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 9ZD 0.612903 0.909091
71 9ZA 0.612903 0.909091
72 3UK 0.610526 0.894737
73 SON 0.604651 0.907895
74 ADP ALF 0.604396 0.848101
75 ALF ADP 0.604396 0.848101
76 PR8 0.604167 0.829268
77 B5V 0.604167 0.883117
78 WAQ 0.604167 0.860759
79 4UV 0.6 0.871795
80 GAP 0.6 0.87013
81 PTJ 0.597938 0.873418
82 FYA 0.597938 0.881579
83 VO4 ADP 0.597826 0.906667
84 ADP VO4 0.597826 0.906667
85 LMS 0.597561 0.829268
86 UP5 0.596154 0.896104
87 FA5 0.59596 0.883117
88 YAP 0.59596 0.871795
89 PAP 0.595506 0.958333
90 A4P 0.59434 0.823529
91 XAH 0.59 0.841463
92 4UU 0.588235 0.871795
93 AFH 0.588235 0.8625
94 9SN 0.585859 0.85
95 2A5 0.58427 0.894737
96 T5A 0.583333 0.821429
97 DQV 0.582524 0.932432
98 NAI 0.580952 0.884615
99 B5M 0.58 0.871795
100 B5Y 0.58 0.871795
101 ITT 0.579545 0.917808
102 ATR 0.577778 0.944444
103 OMR 0.575472 0.831325
104 5AS 0.574713 0.781609
105 YLP 0.571429 0.8
106 48N 0.571429 0.873418
107 AP0 0.570093 0.873418
108 4TC 0.570093 0.873418
109 7D3 0.569767 0.881579
110 ADJ 0.568807 0.831325
111 GNP 0.568421 0.922078
112 9GM 0.568421 0.922078
113 DAL AMP 0.568421 0.881579
114 6V0 0.566038 0.873418
115 TXD 0.566038 0.884615
116 DND 0.566038 0.907895
117 NAX 0.566038 0.851852
118 4UW 0.566038 0.839506
119 NXX 0.566038 0.907895
120 XYA 0.565789 0.821918
121 RAB 0.565789 0.821918
122 ADN 0.565789 0.821918
123 AOC 0.564706 0.8
124 7D4 0.561798 0.881579
125 ADP BMA 0.561224 0.894737
126 TXE 0.560748 0.884615
127 TYM 0.560748 0.883117
128 GA7 0.557692 0.883117
129 YLC 0.555556 0.819277
130 YLB 0.555556 0.8
131 139 0.554545 0.851852
132 5N5 0.551282 0.797297
133 JB6 0.55 0.860759
134 LAQ 0.54717 0.819277
135 F2R 0.544643 0.843373
136 MYR AMP 0.544554 0.797619
137 5CD 0.544304 0.783784
138 A4D 0.544304 0.797297
139 80F 0.54386 0.821429
140 7MD 0.542857 0.864198
141 6AD 0.542553 0.886076
142 A2R 0.541667 0.958904
143 UPA 0.541284 0.884615
144 YLA 0.540541 0.8
145 A A 0.54 0.918919
146 BTX 0.539823 0.821429
147 COD 0.539823 0.793103
148 HFD 0.537634 0.921053
149 G5A 0.537634 0.781609
150 3DH 0.535714 0.753247
151 AYB 0.535714 0.790698
152 CNA 0.535714 0.907895
153 BT5 0.535088 0.811765
154 ATP A A A 0.533981 0.905405
155 IOT 0.531532 0.811765
156 MTA 0.53012 0.753247
157 3AM 0.529412 0.90411
158 A3P 0.52809 0.944444
159 PPS 0.526316 0.851852
160 NAD 0.526316 0.906667
161 EP4 0.52439 0.734177
162 7D5 0.52381 0.855263
163 AMP DBH 0.52381 0.87013
164 J7C 0.522727 0.75
165 A5A 0.520833 0.809524
166 EAD 0.520661 0.851852
167 TSB 0.520408 0.821429
168 AHZ 0.518519 0.797619
169 DTA 0.518072 0.766234
170 M2T 0.518072 0.716049
171 A3D 0.517241 0.894737
172 6RE 0.517241 0.740741
173 YLY 0.516949 0.790698
174 SSA 0.515464 0.802326
175 NA7 0.514852 0.933333
176 ARG AMP 0.514019 0.809524
177 AR6 AR6 0.514019 0.893333
178 7MC 0.513514 0.843373
179 A2P 0.511111 0.930556
180 52H 0.510204 0.781609
181 VMS 0.510204 0.790698
182 54H 0.510204 0.790698
183 TYR AMP 0.509434 0.848101
184 TAD 0.509259 0.8625
185 NAQ 0.508333 0.85
186 A3N 0.505618 0.766234
187 AV2 0.505155 0.893333
188 53H 0.50505 0.781609
189 5CA 0.50505 0.802326
190 8X1 0.50505 0.755556
191 ARU 0.504951 0.839506
192 ZID 0.504132 0.894737
193 P1H 0.504 0.831325
194 NAE 0.5 0.871795
195 3AT 0.5 0.945205
196 AVV 0.5 0.873418
197 P5A 0.495146 0.747253
198 NSS 0.49505 0.802326
199 LSS 0.49505 0.764045
200 DSZ 0.49505 0.802326
201 N0B 0.491803 0.8
202 AF3 ADP 3PG 0.491071 0.817073
203 NVA LMS 0.490196 0.755556
204 DAT 0.489362 0.881579
205 IMO 0.488889 0.90411
206 ZAS 0.488636 0.792208
207 FDA 0.488372 0.813953
208 NAJ PZO 0.487395 0.85
209 4TA 0.487179 0.788235
210 LPA AMP 0.486486 0.797619
211 LEU LMS 0.485437 0.755556
212 DTP 0.484536 0.881579
213 V3L 0.484536 0.945205
214 S4M 0.483516 0.651685
215 GJV 0.483516 0.731707
216 DZD 0.483051 0.8625
217 2AM 0.482759 0.917808
218 5AD 0.481013 0.726027
219 GSU 0.480769 0.781609
220 KAA 0.480769 0.755556
221 NDE 0.480315 0.907895
222 M24 0.479339 0.851852
223 MAO 0.478261 0.761905
224 NEC 0.477778 0.727273
225 DSH 0.477778 0.707317
226 FAS 0.477273 0.831325
227 FAD 0.477273 0.831325
228 RGT 0.476636 0.933333
229 9K8 0.47619 0.698925
230 G A A A 0.474576 0.85
231 0WD 0.474576 0.897436
232 FNK 0.474074 0.786517
233 5X8 0.473684 0.74359
234 6FA 0.473282 0.821429
235 NDC 0.472868 0.85
236 FB0 0.472868 0.786517
237 YSA 0.472222 0.781609
238 7DD 0.468085 0.958333
239 OVE 0.466667 0.881579
240 MHZ 0.463158 0.701149
241 8PZ 0.462963 0.802326
242 A G 0.462185 0.860759
243 AMP NAD 0.462185 0.881579
244 A3G 0.461538 0.779221
245 NAJ PYZ 0.459677 0.809524
246 6C6 0.459184 0.858974
247 SFG 0.458333 0.730769
248 U A G G 0.458333 0.860759
249 7D7 0.45679 0.723684
250 128 0.45614 0.8
251 SFD 0.455224 0.736842
252 6IA 0.454545 0.817073
253 DDS 0.454545 0.855263
254 GDP 0.454545 0.896104
255 ODP 0.453782 0.886076
256 NJP 0.453782 0.921053
257 7DT 0.453608 0.958333
258 A7D 0.452632 0.75641
259 Z5A 0.452381 0.802326
260 WSA 0.452174 0.790698
261 U A 0.45082 0.884615
262 7C5 0.45045 0.797468
263 FAY 0.449275 0.841463
264 NDP 0.449153 0.897436
265 SA8 0.44898 0.690476
266 A5D 0.44898 0.766234
267 71V 0.446809 0.884615
268 GGZ 0.446602 0.804878
269 RFL 0.446043 0.802326
270 2SA 0.445545 0.907895
271 SAI 0.444444 0.716049
272 GP3 0.444444 0.897436
273 SAH 0.444444 0.725
274 PO4 PO4 A A A A PO4 0.443396 0.878378
275 A A A 0.443396 0.881579
276 4YB 0.442478 0.764045
277 SMM 0.441176 0.670455
278 S7M 0.441176 0.674419
279 GTP 0.441176 0.896104
280 Y3J 0.440476 0.706667
281 SAM 0.44 0.674419
282 649 0.439655 0.747253
283 12D 0.438596 0.809524
284 A3S 0.4375 0.789474
285 NPW 0.436975 0.864198
286 GCP 0.436893 0.873418
287 AAT 0.435644 0.690476
288 GNH 0.435644 0.909091
289 EEM 0.435644 0.674419
290 ETB 0.435484 0.813953
291 DCA 0.435484 0.804598
292 N6P 0.433962 0.890411
293 NZQ 0.433333 0.886076
294 TXP 0.433333 0.897436
295 PGS 0.43299 0.860759
296 APU 0.432203 0.871795
297 PUA 0.432 0.8625
298 62F 0.431655 0.841463
299 F2N 0.431507 0.795455
300 DA 0.430108 0.855263
301 D5M 0.430108 0.855263
302 J7V 0.429688 0.813953
303 NIA 0.428571 0.848101
304 COA 0.428571 0.804598
305 6K6 0.428571 0.905405
306 A3T 0.428571 0.8
307 0T1 0.428571 0.804598
308 P5F 0.427586 0.804598
309 AAM 0.425532 0.944444
310 0UM 0.424528 0.682353
311 8Q2 0.423729 0.775281
312 G1R 0.423077 0.884615
313 AMZ 0.422222 0.891892
314 C2R 0.422222 0.88
315 A U 0.420168 0.848101
316 IDP 0.42 0.894737
317 GSP 0.419048 0.851852
318 30N 0.418605 0.736842
319 CAO 0.418605 0.777778
320 DG1 0.418605 0.897436
321 1DG 0.418605 0.897436
322 COS 0.418605 0.786517
323 AMX 0.418605 0.813953
324 TM1 0.418182 0.797619
325 A6D 0.416667 0.746988
326 K15 0.416667 0.666667
327 V1N 0.415929 0.893333
328 CMX 0.415385 0.804598
329 SCO 0.415385 0.804598
330 GEK 0.415094 0.719512
331 XNP 0.414634 0.851852
332 NHD 0.414634 0.881579
333 9JJ 0.413793 0.841463
334 AIR 0.413793 0.876712
335 COK 0.413534 0.786517
336 G2R 0.412844 0.8625
337 ACO 0.412214 0.777778
338 FAM 0.412214 0.786517
339 FCX 0.412214 0.777778
340 NAP 0.410853 0.92
341 FA9 0.409396 0.843373
342 SXZ 0.409091 0.694118
343 HAX 0.409091 0.806818
344 TAP 0.407692 0.884615
345 2MC 0.407407 0.752688
346 62X 0.407407 0.651685
347 GKE 0.40708 0.8625
348 GDC 0.40708 0.8625
349 GDD 0.40708 0.8625
350 3KK 0.406015 0.786517
351 FYN 0.406015 0.804598
352 NVA 2AD 0.405941 0.740741
353 NA0 0.40458 0.907895
354 101 0.404255 0.855263
355 G 0.40404 0.883117
356 5GP 0.40404 0.883117
357 HDV 0.403846 0.87013
358 MGP 0.403846 0.8625
359 OXK 0.402985 0.786517
360 MCD 0.402985 0.786517
361 CA6 0.402985 0.714286
362 SOP 0.402985 0.786517
363 3AD 0.402299 0.783784
364 S8M 0.401869 0.78481
365 YE1 0.40146 0.795455
366 NMX 0.4 0.782609
367 7RP 0.4 0.902778
368 2VA 0.4 0.779221
369 1VU 0.4 0.777778
370 CO6 0.4 0.786517
371 CMC 0.4 0.786517
372 6G0 0.4 0.8625
373 GMV 0.4 0.873418
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3KN5; Ligand: ANP; Similar sites found with APoc: 391
This union binding pocket(no: 1) in the query (biounit: 3kn5.bio2) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 5HP8 PYR None
2 3V2Q PLM None
3 1GSA ADP 0.949367
4 1Z2P I3S 1.23457
5 1Z2P ACP 1.23457
6 1KJ8 ATP 1.53846
7 1KJ8 GAR 1.53846
8 4FMU 0UM 1.79856
9 5I35 ANP 1.84615
10 2VPQ ANP 1.84615
11 3WO0 ADP 1.84615
12 3WO0 ALA 1.84615
13 3K5I ADP 1.84615
14 3K5I AIR 1.84615
15 5C1P DAL DAL 1.96078
16 5C1P ADP 1.96078
17 3VPC ADP 2.12766
18 4OCV ANP 2.15385
19 3V4S ATP 2.15385
20 2IO8 ADP 2.15385
21 1M0W ANP 2.15385
22 3V4S ADP 2.15385
23 2Q7D ANP 2.15385
24 3VSV XYS 2.15385
25 5UIJ TYD 2.15385
26 2WKV COA 2.15385
27 2QK4 ATP 2.21239
28 1I7L ATP 2.26537
29 1E4E ADP 2.46154
30 1YFS ALA 2.46154
31 4RDL FUC GAL NDG FUC 2.5974
32 1IOW PHY 2.61438
33 1IOW ADP 2.61438
34 5ZCT ANP 2.61438
35 4AF5 CIT 2.63158
36 5IH1 6BQ 2.64901
37 5IH1 GDP 2.64901
38 2XOC ADP 2.68199
39 6FL8 ADP 2.76923
40 6FL8 TIY 2.76923
41 1PK8 ATP 2.76923
42 3UDZ ADP 2.76923
43 4U98 ACP 2.76923
44 1VEM GLC GLC 2.76923
45 6AM8 PLT 2.76923
46 4O4F ATP 2.82258
47 4O4F IHP 2.82258
48 1AUX AGS 2.89389
49 5IGI ZIT 2.99003
50 5IGI GMP 2.99003
51 3TM0 B31 3.04183
52 3TM0 ANP 3.04183
53 2IF8 ADP 3.07692
54 2V58 LZJ 3.07692
55 3DNT ATP 3.07692
56 4UWH JXM 3.07692
57 6H3O FAD 3.07692
58 4MV1 ADP 3.07692
59 4PZ6 GMP 3.07692
60 3FPF TNA 3.07692
61 3FPF MTA 3.07692
62 6EAC ANP 3.07692
63 4WOP CTP 3.11111
64 4KM2 TOP 3.35196
65 4KM2 ATR 3.35196
66 4NZN 2OU 3.38462
67 4NZN ANP 3.38462
68 2VQD AP2 3.69231
69 3KAL ADP 3.69231
70 3TII ANP 3.69231
71 1ZDQ MSM 3.69231
72 3TTM PUT 3.69231
73 6F9G PUT 3.73832
74 1VG8 GNP 3.86473
75 4ZS4 ATP 3.90879
76 2YW2 ATP 4
77 1ZX5 LFR 4
78 3RG9 WRA 4.16667
79 2PUL ACP 4.30769
80 5LXT ACP 4.30769
81 5OES ADP 4.30769
82 3WYJ H78 4.34783
83 3PDT ADP 4.36364
84 3ZLR X0B 4.43038
85 5L3R GCP 4.43686
86 4ZGP ADP 4.43686
87 4OCJ NDG 4.61538
88 1T36 ADP 4.61538
89 1CKM GTP 4.61538
90 1PVN MZP 4.61538
91 2R3A SAM 4.66667
92 4DP3 NDP 4.76974
93 4DP3 MMV 4.76974
94 4GYI ADP 4.92308
95 3W0O ADP 4.92308
96 3W0O HY0 4.92308
97 3I0O ADP 4.92308
98 3ETH ATP 4.92308
99 3X01 AMP 4.92308
100 5TDF ADP 4.93827
101 3ZS7 ATP 5
102 5G5G MCN 5.03145
103 4EN4 GT1 5.12821
104 4EN4 GT0 5.12821
105 4EN4 ATP 5.12821
106 2PYW ADP 5.23077
107 4CYI ATP 5.23077
108 2R7K ACP 5.23077
109 2R7K AMZ 5.23077
110 4Z4P SAH 5.42169
111 1TZD ADP 5.45455
112 5EQY 5RA 5.53846
113 3WVR AMP 5.53846
114 4JB1 NAP 5.53846
115 4JB1 FAD 5.53846
116 6GG9 FMN 5.55556
117 5GZ9 ANP 5.57377
118 1P6O HPY 5.59006
119 3VPD ANP 5.69395
120 4L2I FAD 5.70342
121 4CS9 AMP 5.82011
122 4OAV ACP 5.84615
123 3VOT ADP 5.84615
124 6DW2 HD4 5.90717
125 4O9S 2RY 6.04651
126 5TT6 ATP 6.15385
127 3BP1 GUN 6.2069
128 6CGD AKN 6.22951
129 6CGD GNP 6.22951
130 4J7U NAP 6.25
131 4J7U YTZ 6.25
132 5A89 FMN 6.41026
133 1W2D 4IP 6.41509
134 1W2D ADP 6.41509
135 2XG5 EC5 6.42202
136 2XG5 EC2 6.42202
137 5MW8 ATP 6.46154
138 5AE9 OKO 6.46154
139 6EZ6 C5Z 6.46154
140 4ZOH MCN 6.54762
141 2HGS ADP 6.76923
142 2QF7 AGS 6.76923
143 5VLQ ANP 6.76923
144 2J73 GLC GLC GLC 6.79612
145 2WT9 NIO 6.80851
146 4LH7 1X8 6.81115
147 5C4L 4XR 6.85358
148 5C4L SIS 6.85358
149 4C5N ACP 6.88406
150 2QX0 PH2 6.91824
151 2AQX ATP 6.92042
152 6C1S EFV 7.07692
153 4PU5 ANP 7.07692
154 2Z49 AMG 7.07692
155 1EHI ADP 7.38462
156 3ORQ ADP 7.38462
157 5DZT AMP 7.38462
158 1GZ4 ATP 7.38462
159 2CFM AMP 7.38462
160 1F1V DHY 7.43034
161 1XRO LEU 7.84983
162 4XYM A12 8.26087
163 4XZ3 ACP 8.26087
164 1JBU BEN 8.26772
165 1TQP ATP 8.51064
166 3AXM 6PG 8.52713
167 2YRX AMP 8.61539
168 6A5K SAM 8.61539
169 6MJ7 ARG 9.09091
170 5K2M ADP 9.43396
171 2BKK ADP 9.46746
172 5VZ0 ADP 9.53846
173 3TDV GDP 9.80392
174 3ZS9 ADP ALF 9.84615
175 2P3B 3TL 10.101
176 6E8I PTR 10.6509
177 1JG3 ADN 11.0638
178 4R78 AMP 11.3269
179 4AZW ATP 11.6923
180 5L3S GNP 12
181 3VPB ADP 12.5
182 3VHE 42Q 13.5385
183 4ASE AV9 13.5385
184 5HSA FAS 13.5385
185 5YK1 ANP 13.8462
186 1AE1 NAP 13.9194
187 4AG8 AXI 13.9241
188 4WW7 AMP 14.1762
189 3LQV ADE 14.7826
190 6GWR FEW 14.9206
191 1ZTH ADP 15.1163
192 1ZP9 ATP 15.1163
193 5CKW ANP 15.3846
194 1IA9 ANP 16.7857
195 2UYN 2KT 17.0543
196 3HAV ATP 17.0569
197 4Q5H ANP 18.4211
198 2QLU ADE 19.4268
199 5QIN J2V 19.9367
200 2GQR ADP 20.2532
201 5C03 AGS 20.3077
202 3C1X CKK 20.6154
203 5EOB 5QQ 20.6897
204 4WOV 3SM 20.8202
205 2GQS ADP 21.097
206 4CLI 5P8 21.4067
207 5WNL STU 22.1538
208 4O1P ANP 22.1538
209 3H9R TAK 22.7692
210 6ES0 BW8 23.3438
211 3KRL KRL 23.3846
212 1Y57 MPZ 23.6923
213 2H8H H8H 23.6923
214 1JPA ANP 24.0385
215 5MJA 7O3 24.918
216 3GNI ATP 25.5385
217 4XH0 ADP 25.5385
218 4IX4 ADP 26.1538
219 1BYG STU 26.259
220 5CEO 50D 26.3333
221 5LPZ ADP 26.7692
222 4KBA 1QM 26.7692
223 3G5D 1N1 26.9231
224 6GIN IR2 27.2425
225 3E8N ATP 27.6923
226 3E8N VRA 27.6923
227 5OKT 9XK 27.707
228 1VJY 460 28.3828
229 2OFV 242 28.5199
230 4BTK DTQ 28.6154
231 5LPB ADP 29.3919
232 5KO1 6UY 29.682
233 5WO4 B7V 29.8013
234 5U6C 7YS 29.8413
235 5T8O 76Z 29.8462
236 2PVF ACP 29.8462
237 4IDT T28 29.8462
238 5HCY 60D 29.8462
239 4P5Z Q7M 29.8462
240 3NW7 LGV 29.9674
241 5MY8 RXZ 30.1538
242 3GQI ACP 30.1538
243 2X2M X2M 30.2548
244 5HES 032 30.2932
245 4E93 GUI 30.4615
246 4K33 ACP 30.4615
247 5UR1 YY9 30.5466
248 3RI1 3RH 30.6709
249 1K3A ACP 30.7692
250 3LXN MI1 30.8176
251 5ZTN CUR 31.0769
252 3PP0 03Q 31.0769
253 6A1G 9OL 31.3846
254 6FYV 3NG 31.3846
255 1U5R ATP 31.3846
256 6C7Y ADP 31.4685
257 4RFM 3P6 31.5789
258 3VRY B43 31.6923
259 2CSN CKI 31.9865
260 3LXK MI1 32
261 5Y86 HRM 32
262 4Y93 746 32
263 5JKG 6LF 32.1543
264 2F57 23D 32.1767
265 1OPK P16 32.3077
266 4AU8 Z3R 32.4324
267 4GJ3 0XP 32.4503
268 2XVD AS6 32.4503
269 4FL3 ANP 32.6154
270 2Y6O 1N1 32.646
271 5USZ SKE 32.872
272 3O0G 3O0 32.8767
273 1UNH IXM 32.8767
274 3PLS ANP 32.8859
275 4UXL 5P8 33.2298
276 2JLD AG1 33.2308
277 3F7Z 34O 33.2308
278 4NM5 ADP 33.2308
279 3ZRM ZRM 33.2308
280 6GQM F8H 33.5385
281 4QMN DB8 33.5484
282 4U0I 0LI 33.6508
283 3KMW ATP 34.1085
284 3SLS ANP 34.2105
285 4FF8 14S 34.3653
286 5TO8 7FM 34.3972
287 4OTH DRN 34.4615
288 5NKB 8ZT 34.6405
289 4E1Z 0MX 34.7079
290 3UIM ANP 34.7692
291 2A19 ANP 34.8592
292 3GC0 AMP 34.9544
293 4YZC STU 35.0769
294 5H2U 1N1 35.206
295 6CZ3 FLJ 35.2273
296 4Y85 499 35.3846
297 4EWH T77 35.6364
298 2OO8 RAJ 35.6467
299 3BZ3 YAM 36.2319
300 1IR3 ANP 36.6013
301 3EKK GS2 36.8078
302 3BU5 ATP 36.9281
303 4CRL C1I 37.2308
304 5DBX ANP 37.2308
305 3SXS PP2 37.6866
306 5JGA 6KC 37.7778
307 3TXO 07U 37.8462
308 4WNK 453 37.8462
309 4BHN BH9 37.8462
310 4TWP AXI 38.0074
311 5FBN 5WF 38.0074
312 2HK5 1BM 38.1481
313 3GC8 B45 38.1538
314 1XJD STU 38.4615
315 4YMJ 4EJ 38.8158
316 3SRV S19 38.9892
317 3PVW QRX 39.0769
318 5UKL SIX 39.0769
319 5VC5 96M 39.1003
320 1U59 STU 39.3728
321 2QCS ANP 39.3846
322 4F4P 0SB 39.5604
323 4CSV STI 39.6364
324 2WU6 DKI 39.6923
325 3ALN ANP 39.6923
326 1O9U ADZ 39.6923
327 1RE8 BD2 40
328 2GU8 796 40
329 5X8I SQZ 40
330 3IDB ANP 40
331 3FHI ANP 40
332 6G33 5ID 40
333 3HMO STU 40
334 4QTB 38Z 40.3077
335 4WB7 ATP 40.3077
336 5EFQ ADP 40.3077
337 5HQ0 LZ9 40.3974
338 6GU6 1QK 40.3974
339 5JFS 6K0 40.5844
340 4WB6 ATP 40.6154
341 4AUA 4AU 40.7166
342 2B9H ADP 40.9231
343 2B9J ADP 40.9231
344 2B9I ADP 40.9231
345 3PTG 932 40.9231
346 3TTI KBI 40.9231
347 1CM8 ANP 40.9231
348 4WHZ 3NL 40.9231
349 5LI1 ANP 41.2308
350 2B9F ADP 41.2308
351 1OUK 084 41.2308
352 3E7O 35F 41.2308
353 4LOO SB4 41.2308
354 6C0T EE4 41.5385
355 4NST ADP 41.5385
356 5LI9 ACP 41.5385
357 6E2O S0L 41.6949
358 5N87 N66 41.853
359 2F2U M77 42.4615
360 4DC2 ADE 42.4615
361 5EKO N17 42.4615
362 2BPM 529 42.7184
363 4H3P ANP 42.7692
364 4H3Q ANP 42.7692
365 4BCN T9N 43
366 5BVE 4VG 43.0769
367 1ZY5 ANP 43.2343
368 2XMY CDK 43.2886
369 6FYL 3NG 43.3846
370 4PNI KQQ 43.3846
371 4L9I 8PR 43.3846
372 5TA6 79D 43.3846
373 4CFU 2WC 43.5644
374 6GUE FB8 43.7086
375 4BCQ TJF 43.8538
376 4BCM T7Z 43.8538
377 1V0O INR 44.0972
378 3FC2 IBI 44.3077
379 5AWM ANP 44.3077
380 5LMK 6ZK 44.4444
381 4UX9 ANP 44.9231
382 4IZY 1J2 44.9231
383 6CMJ F6J 46.4174
384 4AT3 LTI 46.4883
385 3HZT J60 47.3846
386 2ZV2 609 47.651
387 2V7O DRN 48.3077
388 5EH0 5NW 48.4496
389 2WEL K88 48.9231
390 4I6H 1C8 49.6753
391 4FG8 ATP 49.8413
Pocket No.: 2; Query (leader) PDB : 3KN5; Ligand: ANP; Similar sites found with APoc: 45
This union binding pocket(no: 2) in the query (biounit: 3kn5.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
1 1ME8 RVP 1.53846
2 3KJS DQ1 1.53846
3 2NZU BG6 1.78571
4 1F0X FAD 1.84615
5 4EIL NDP 2.46154
6 4Y4V DAL 2.76923
7 1TT8 PHB 3.04878
8 5DXT 5H5 3.07692
9 4FE2 ADP 3.13725
10 1U72 MTX 3.22581
11 1U72 NDP 3.22581
12 5EXK MET 3.38462
13 4TVD BGC 3.38462
14 2CIG 1DG 3.77358
15 5HSS 64Z 4
16 3FU7 3DM 4
17 2WKQ GTP 4.30769
18 1VL8 NAP 4.49438
19 1CKN GTP 4.61538
20 6ARJ SAH 4.61538
21 3PN1 IVH 4.71698
22 4NFE BEN 5.06329
23 3ZJX BOG 5.19031
24 4LED XXR 5.59701
25 1OBD ATP 6.20915
26 1M26 GAL A2G 6.76692
27 2GJ5 VD3 6.79012
28 2J73 GLC GLC GLC GLC 6.79612
29 1S68 AMP 6.82731
30 4DFU QUE 6.8323
31 4C5N PXL 6.88406
32 2Z48 A2G 7.07692
33 2Z48 NGA 7.07692
34 2FPU HSO 7.38636
35 5WBF LAC 7.77778
36 5YW5 ADE 7.82123
37 6APF CIT 7.82918
38 4LO2 GAL BGC 8.44595
39 1N7G NDP 9.84615
40 1RJ9 GCP 10.1974
41 5FI4 5XV 10.8359
42 3O5N BR0 11.6071
43 4MZU TDR 13.7821
44 4OUJ LBT 14.0065
45 2CBT TH2 17.8571
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