-->
Receptor
PDB id Resolution Class Description Source Keywords
3M89 2 Å NON-ENZYME: OTHER STRUCTURE OF TUBZ-GTP-G-S BACILLUS THURINGIENSIS PARTITION TUBULIN FTSZ TUBZ GTP-BINDING NUCLEOTIDE-BINDSTRUCTURAL PROTEIN
Ref.: FROM THE COVER: PLASMID PROTEIN TUBR USES A DISTINC HTH-DNA BINDING AND RECRUITS THE PROKARYOTIC TUBULI TUBZ TO EFFECT DNA PARTITION. PROC.NATL.ACAD.SCI.USA V. 107 11763 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GSP A:408;
Valid;
none;
Kd = 0.69 uM
539.246 C10 H16 N5 O13 P3 S c1nc2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3M89 2 Å NON-ENZYME: OTHER STRUCTURE OF TUBZ-GTP-G-S BACILLUS THURINGIENSIS PARTITION TUBULIN FTSZ TUBZ GTP-BINDING NUCLEOTIDE-BINDSTRUCTURAL PROTEIN
Ref.: FROM THE COVER: PLASMID PROTEIN TUBR USES A DISTINC HTH-DNA BINDING AND RECRUITS THE PROKARYOTIC TUBULI TUBZ TO EFFECT DNA PARTITION. PROC.NATL.ACAD.SCI.USA V. 107 11763 2010
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 3M89 Kd = 0.69 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 3M89 Kd = 0.69 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 3M89 Kd = 0.69 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GSP; Similar ligands found: 139
No: Ligand ECFP6 Tc MDL keys Tc
1 GSP 1 1
2 GP3 0.897436 0.925
3 GTP 0.853659 0.948718
4 GNH 0.829268 0.936709
5 GDP 0.817073 0.948718
6 G1R 0.8 0.936709
7 GCP 0.77907 0.925
8 GNP 0.770115 0.925
9 9GM 0.770115 0.925
10 GMV 0.767442 0.925
11 G 0.756098 0.935897
12 5GP 0.756098 0.935897
13 G2R 0.747253 0.91358
14 GDD 0.744681 0.91358
15 GDC 0.744681 0.91358
16 GKE 0.744681 0.91358
17 GPG 0.73913 0.91358
18 GTG 0.736842 0.891566
19 G3A 0.729167 0.925
20 G5P 0.721649 0.925
21 GDR 0.71875 0.91358
22 GFB 0.71875 0.91358
23 GAV 0.714286 0.987179
24 GP2 0.712644 0.91358
25 6CK 0.71134 0.891566
26 Y9Z 0.708333 0.860465
27 JB2 0.69697 0.91358
28 GKD 0.69697 0.91358
29 G2P 0.692308 0.91358
30 GDX 0.69 0.925
31 GPD 0.69 0.880952
32 ALF 5GP 0.67033 0.847059
33 0O2 0.666667 0.935897
34 YGP 0.663265 0.858824
35 JB3 0.657143 0.902439
36 GDP ALF 0.645833 0.847059
37 GDP AF3 0.645833 0.847059
38 ALF GDP 0.645833 0.847059
39 GMP 0.641975 0.835443
40 G3D 0.638298 0.935897
41 NGD 0.635514 0.91358
42 2MD 0.633027 0.894118
43 CAG 0.630631 0.840909
44 G4P 0.625 0.935897
45 FEG 0.62037 0.83908
46 U2G 0.62037 0.891566
47 G G 0.617647 0.901235
48 MGD 0.616071 0.894118
49 ZGP 0.614679 0.872093
50 CG2 0.609091 0.891566
51 TPG 0.598291 0.804348
52 3GP 0.595506 0.898734
53 GDP 7MG 0.590476 0.86747
54 GH3 0.581633 0.924051
55 PGD 0.581197 0.926829
56 MD1 0.581197 0.894118
57 2GP 0.577778 0.911392
58 GCP G 0.563107 0.875
59 DGT 0.561224 0.878049
60 DBG 0.558333 0.902439
61 G1G 0.550847 0.880952
62 AGS 0.547368 0.924051
63 SAP 0.547368 0.924051
64 FE9 0.546219 0.8
65 A G 0.543103 0.888889
66 G4M 0.539062 0.840909
67 U A G G 0.538462 0.888889
68 G A A A 0.529915 0.878049
69 MGP 0.525253 0.91358
70 GPX 0.524272 0.898734
71 BGO 0.521739 0.879518
72 DGI 0.520408 0.878049
73 6G0 0.52 0.91358
74 IDP 0.515464 0.923077
75 R7I 0.51 0.898734
76 R5I 0.51 0.898734
77 GGM 0.508475 0.858824
78 G1R G1R 0.508065 0.879518
79 PGD O 0.504 0.875
80 AKW 0.495726 0.915663
81 G U 0.491525 0.857143
82 GTA 0.486726 0.891566
83 P2G 0.484536 0.839506
84 GPC 0.483607 0.83908
85 G C 0.483333 0.857143
86 P1G 0.474747 0.829268
87 DG 0.474227 0.865854
88 DGP 0.474227 0.865854
89 BA3 0.46875 0.85
90 IMP 0.463918 0.910256
91 B4P 0.463918 0.85
92 AP5 0.463918 0.85
93 G2Q 0.462963 0.91358
94 G G G RPC 0.459016 0.833333
95 APC G U 0.456 0.843373
96 ATP 0.45 0.873418
97 HEJ 0.45 0.873418
98 G G G C 0.448819 0.869048
99 A2D 0.447917 0.85
100 5FA 0.445545 0.873418
101 AQP 0.445545 0.873418
102 A G C C 0.445312 0.86747
103 G7M 0.444444 0.901235
104 G U34 0.442623 0.847059
105 01G 0.442478 0.860465
106 ITT 0.44 0.825
107 SGP 0.44 0.876543
108 HFD 0.436893 0.831325
109 G C C C 0.431818 0.879518
110 AT4 0.43 0.911392
111 AN2 0.43 0.8625
112 DG DG 0.428571 0.825581
113 A4P 0.42623 0.829545
114 UCG 0.424242 0.86747
115 PCG 0.423077 0.886076
116 C2E 0.423077 0.875
117 35G 0.423077 0.886076
118 MGO 0.420561 0.823529
119 ADP 0.42 0.873418
120 ANP 0.419048 0.851852
121 5GP 5GP 0.419048 0.839506
122 ADQ 0.418182 0.829268
123 7DT 0.417476 0.860759
124 AR6 0.417476 0.85
125 APR 0.417476 0.85
126 PRT 0.417391 0.910256
127 C1Z 0.415929 0.935897
128 A G U 0.414286 0.847059
129 AD9 0.413462 0.851852
130 UP5 0.413223 0.831325
131 A22 0.412844 0.8625
132 25L 0.412281 0.8625
133 M33 0.411765 0.839506
134 JBT 0.410405 0.783505
135 ACP 0.407767 0.851852
136 6YZ 0.407407 0.851852
137 ACQ 0.40566 0.851852
138 A1R 0.405405 0.8
139 A G U U 0.4 0.847059
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3M89; Ligand: GSP; Similar sites found with APoc: 277
This union binding pocket(no: 1) in the query (biounit: 3m89.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 4RSL FAD 1.40515
2 4PIV NDP 1.40515
3 9LDT NAD 1.50602
4 9LDB NAD 1.50602
5 4XYB NDP 1.53453
6 2J5V PCA 1.63488
7 1ZGS XMM 1.63934
8 4Q4K FMN 1.68067
9 4GKV NAD 1.78571
10 6BII NAP 1.8018
11 5NUE NAD 1.80723
12 5NUF NAD 1.80723
13 2RHO GDP 1.84615
14 2RHO GSP 1.84615
15 1UWK NAD 1.87354
16 1UWK URO 1.87354
17 5JFL NAD 1.87354
18 2FR1 NDP 1.87354
19 4KP7 NAP 1.87354
20 6F97 FAD 1.87354
21 4KP7 1UQ 1.87354
22 5GUD NDP 1.87354
23 1I8T FAD 1.90736
24 1ZK4 NAP 1.99203
25 1ZK4 AC0 1.99203
26 2R75 01G 2.07101
27 4DXD GDP 2.10773
28 1RM0 NAI 2.10773
29 2GJP MAL 2.10773
30 1MUU NAD 2.10773
31 1MV8 NAD 2.10773
32 6F3M NAD 2.10773
33 4TXI FAD 2.10773
34 4E5N NAD 2.12121
35 5T9F TYR 2.21402
36 1YKF NAP 2.27273
37 4J6O CIT 2.27273
38 1YJQ NAP 2.31023
39 3I6I NDP 2.31214
40 1D4D FAD 2.34192
41 5MW4 5JU 2.34192
42 3RJ5 NAD 2.3622
43 5U5G NAP 2.37288
44 2GNB MAN 2.38095
45 1PZG A3D 2.41692
46 5F5N NAD 2.42215
47 3H4V NAP 2.43056
48 3H4V DVP 2.43056
49 1LDM NAD 2.43161
50 1V35 NAI 2.43161
51 3HBN UDP 2.48227
52 2A92 NAI 2.49221
53 2FK8 SAM 2.51572
54 4YRY FAD 2.53623
55 1SB8 UD2 2.55682
56 1SB8 NAD 2.55682
57 5A89 FMN 2.5641
58 5A89 ADP 2.5641
59 1P77 ATR 2.57353
60 6F7L FAD 2.57611
61 1HYH NAD 2.589
62 4ZGS NAD 2.59067
63 5GT9 NAP 2.6616
64 4DE3 DN8 2.6616
65 4ZVV NAD 2.71084
66 4ZVV GN0 2.71084
67 4YCA NDP 2.72109
68 1JQD SAH 2.73973
69 3W8X FTK 2.8103
70 3W8X FAD 2.8103
71 1CDO NAD 2.8103
72 5Y77 FAD 2.8103
73 4IOK ADP 2.8103
74 2BGM NAJ 2.8777
75 2VHW NAI 2.91777
76 4WGF HX2 2.92683
77 4RF2 NAP 2.94118
78 1OJ7 NZQ 2.94118
79 1F8F NAD 2.96496
80 5AOV NAP 2.97619
81 3RFV 15L 2.99625
82 3RFV NAI 2.99625
83 4PLT NAI 3.02115
84 5M67 NAD 3.0445
85 5M67 3D1 3.0445
86 5M67 ADE 3.0445
87 1ZEM NAD 3.05344
88 5FFF NAP 3.11284
89 1RQ2 CIT 3.14136
90 1TDF NAP 3.16456
91 1TDF FAD 3.16456
92 1ORR NAD 3.17003
93 5ZI2 ADP 3.18841
94 5ZI2 NAD 3.18841
95 1E3I CXF 3.19149
96 5KKA 6V0 3.20513
97 4ZRN NAD 3.20513
98 1GV0 NAD 3.22581
99 1GUZ NAD 3.22581
100 1EQ2 NAP 3.22581
101 1XG5 NAP 3.22581
102 1NVM NAD 3.27869
103 1N1G BCP 3.27869
104 5MSO NAP 3.27869
105 2Q4W FAD 3.27869
106 4PLG NAI 3.29341
107 4PLG OXM 3.29341
108 1AE1 NAP 3.2967
109 2HJR APR 3.35366
110 1PL6 NAD 3.37079
111 1PL6 572 3.37079
112 1BW9 NAD 3.37079
113 1BXG NAD 3.37079
114 4D86 ADP 3.37349
115 1C1X NAD 3.38028
116 1T26 GBD 3.41615
117 1T26 NAI 3.41615
118 1LTH NAD 3.44828
119 1A5Z NAD 3.44828
120 6GNA FAD 3.47222
121 1D1T NAD 3.48525
122 1P0F NAP 3.48525
123 1NNU TCT 3.49345
124 1NNU NAD 3.49345
125 3WQQ IB3 3.51288
126 3WQQ NDP 3.51288
127 1KOL NAD 3.51759
128 4MO2 FAD 3.53261
129 4MO2 FDA 3.53261
130 4L8V NAP 3.56083
131 3SJ7 NDP 3.57143
132 5X68 FAD 3.58056
133 1Y8Q ATP 3.74707
134 5Z20 NAI 3.76812
135 4KWI 1TJ 3.80228
136 4KWI NAP 3.80228
137 3WLE NAD 3.81232
138 1RJW ETF 3.83481
139 3VPH NAD 3.87097
140 3VPH OXM 3.87097
141 1WVG APR 3.89972
142 1SOW NAD 3.96341
143 1W5F G2P 3.96601
144 2CVQ NDP 3.97554
145 1R6D NAD 3.98126
146 1R6D DAU 3.98126
147 3CTY FAD 3.98126
148 2XZ9 PYR 4.01235
149 5K4W THR 4.04984
150 5K4W NAI 4.04984
151 2Q0L FAD 4.18006
152 5AYV NAP 4.20712
153 5AYV KPL 4.20712
154 1V59 FAD 4.21546
155 6CI9 NAP 4.2471
156 5THQ NDP 4.41176
157 1H9A NAP 4.44965
158 5OCM NAP 4.46735
159 3KB6 NAD 4.49102
160 3HVJ 705 4.52489
161 2JHF NAD 4.54545
162 2DFV NAD 4.61095
163 5VN0 NAI 4.6332
164 2F5Z FAD 4.6875
165 5OJL TXP 4.69799
166 1PJS NAD 4.814
167 2FZW NAD 4.82574
168 1KEV NDP 4.8433
169 3GFB NAD 4.85714
170 3OND ADN 4.91803
171 3OND NAD 4.91803
172 2CDC NAP 4.91803
173 2CDC XYS 4.91803
174 2CDC XYP 4.91803
175 1GZ4 ATP 4.91803
176 6EOA FMN 4.92308
177 5EEH P9P 5.05319
178 5EEH SAH 5.05319
179 2DC1 NAD 5.08475
180 2BQP GLC 5.12821
181 5VFC 9BA 5.14469
182 2ZXI FAD 5.15223
183 1V8B NAD 5.15223
184 4OOE NDP 5.15223
185 4OOE FOM 5.15223
186 3HB5 NAP 5.19878
187 3LU1 NAD 5.21978
188 1H2B NAJ 5.29248
189 4JNE ATP 5.38642
190 5J5R IMP 5.39846
191 5J5R 6G1 5.39846
192 4LS3 HIS 5.40541
193 5KGS 6SR 5.62061
194 1UDB UFG 5.6213
195 1UDB NAD 5.6213
196 1LDN NAD 5.6962
197 2EV9 NAP 5.70342
198 2EV9 SKM 5.70342
199 2Q1W NAD 5.70571
200 1OC2 NAD 5.74713
201 1OC2 TDX 5.74713
202 1H3F TYE 5.8548
203 1BXK NAD 5.91549
204 3FG2 FAD 5.94059
205 3GGO NAI 6.05096
206 3GGO ENO 6.05096
207 4W6Z 8ID 6.05187
208 2O4C NAD 6.05263
209 2ZJ1 ARJ 6.08899
210 2ZJ1 NAD 6.08899
211 4O1M NAD 6.08899
212 5JCA FAD 6.08899
213 5Z2L NDP 6.12245
214 4DPL NAP 6.12813
215 4NBW NAD 6.22568
216 5ZZ6 NAD 6.25
217 1WHT BZS 6.25
218 6CEP NAD 6.28743
219 6CEP OXM 6.28743
220 1R37 NAD 6.34006
221 1U3U BNF 6.41711
222 1U3U NAD 6.41711
223 5FEU NAP 6.52921
224 2G50 PYR 6.55738
225 1PFK ADP 6.5625
226 3VZS NAP 6.61479
227 3VZS CAA 6.61479
228 1PNO NAP 6.66667
229 1OFU GDP 6.72269
230 4TQG NDP 6.81115
231 3ABI NAD 6.84932
232 2Q1S NAI 6.89655
233 4J4H NAI 6.94981
234 4J4H 1J1 6.94981
235 4JK3 NAD 6.94981
236 5Z21 NAI 7.02576
237 4Q9N NAI 7.04698
238 4E13 NAD 7.06714
239 3QV1 NAD 7.12166
240 2RH4 EMO 7.22022
241 3HRD MCN 7.27273
242 2AE2 PTO 7.30769
243 2AE2 NAP 7.30769
244 1C3V NDP 7.34694
245 5EIN NAP 7.40741
246 2VAP GDP 7.49415
247 1FL2 FAD 7.49415
248 3ORF NAD 7.56972
249 1M0S CIT 7.76256
250 5XDT GDP 7.79221
251 5XDT MB3 7.79221
252 1EZ4 NAD 7.86164
253 4RQU NAD 8
254 2PZM UDP 8.18182
255 2PZM NAD 8.18182
256 6BWL NAD 8.23171
257 1NM5 NAP 8.33333
258 1NM5 NAD 8.33333
259 1J49 NAD 8.40841
260 4CQM NAP 8.81226
261 1MVN PCO 9.56938
262 1MVN FMN 9.56938
263 1YB5 NAP 9.68661
264 2GAG NAD 10
265 5ODQ FAD 10
266 2NU8 COA 10.0703
267 6AA8 NAD 10.2649
268 5GM1 SAH 10.5386
269 6BYF CIT 10.5882
270 3B1F NAD 10.6897
271 1EBF NAD 11.1732
272 3CB2 GDP 11.2412
273 2DTX BMA 12.1212
274 5L95 AMP 12.5
275 4R57 ACO 15.9091
276 1LES GLC FRU 19.2308
277 4EI7 GDP 23.9075
APoc FAQ
Feedback