Receptor
PDB id Resolution Class Description Source Keywords
3P5G 1.6 Å NON-ENZYME: BINDING STRUCTURE OF THE CARBOHYDRATE-RECOGNITION DOMAIN OF HUMAN LA WITH BLOOD GROUP B TRISACCHARIDE (GAL ALPHA1-3(FUC ALPHA1-2 HOMO SAPIENS C-TYPE LECTIN CARBOHYDRATE-BINDING SUGAR BINDING PROTEIN
Ref.: STRUCTURAL BASIS FOR LANGERIN RECOGNITION OF DIVERS PATHOGEN AND MAMMALIAN GLYCANS THROUGH A SINGLE BIN SITE. J.MOL.BIOL. V. 405 1027 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CA A:500;
B:500;
C:500;
D:500;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
40.078 Ca [Ca+2...
FUC C:402;
D:402;
Valid;
Valid;
none;
none;
submit data
164.156 C6 H12 O5 C[C@H...
GLA GAL FUC A:400;
Valid;
none;
submit data
488.439 n/a O(C1O...
GLA GLA FUC B:400;
Valid;
none;
submit data
488.439 n/a O(C1O...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3P7G 1.5 Å NON-ENZYME: BINDING STRUCTURE OF THE HUMAN LANGERIN CARBOHYDRATE RECOGNITION DOM COMPLEX WITH MANNOSE HOMO SAPIENS C-TYPE LECTIN MEMBRANE PROTEIN GLYCOPROTEIN LANGERIN DC-CARBOHYDRATE BINDING PROTEIN CALCIUM BINDING SUGAR BINDINSYSTEM LANGERHANS CELLS CD207
Ref.: THE CARBOHYDRATE RECOGNITION DOMAIN OF LANGERIN REV STRUCTURAL SIMILARITY WITH THE ONE OF DC-SIGN BUT A ADDITIONAL, CALCIUM-INDEPENDENT SUGAR-BINDING SITE. MOL.IMMUNOL. V. 45 1981 2008
Members (15)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 473 families.
1 3P7G - MAN C6 H12 O6 C([C@@H]1[....
2 4N36 - 2F8 C9 H17 N O6 CC(=O)N[C@....
3 4N33 - NAG GAL BGC n/a n/a
4 3P5I - G6S NAG n/a n/a
5 3P5H - BGC BGC n/a n/a
6 4N37 - MMA C7 H14 O6 CO[C@@H]1[....
7 4N34 - 2F8 C9 H17 N O6 CC(=O)N[C@....
8 3P5E - MAN C6 H12 O6 C([C@@H]1[....
9 3P5D - MAN C6 H12 O6 C([C@@H]1[....
10 3P5G - FUC C6 H12 O5 C[C@H]1[C@....
11 4N32 - 2F8 C9 H17 N O6 CC(=O)N[C@....
12 3P7H - MAL C12 H22 O11 C([C@@H]1[....
13 4N38 - NAG GAL n/a n/a
14 4N35 - NAG GAL BGC n/a n/a
15 3P5F - MAN C6 H12 O6 C([C@@H]1[....
70% Homology Family (16)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 355 families.
1 3P7G - MAN C6 H12 O6 C([C@@H]1[....
2 4N36 - 2F8 C9 H17 N O6 CC(=O)N[C@....
3 4N33 - NAG GAL BGC n/a n/a
4 3P5I - G6S NAG n/a n/a
5 3P5H - BGC BGC n/a n/a
6 4N37 - MMA C7 H14 O6 CO[C@@H]1[....
7 4N34 - 2F8 C9 H17 N O6 CC(=O)N[C@....
8 3P5E - MAN C6 H12 O6 C([C@@H]1[....
9 3P5D - MAN C6 H12 O6 C([C@@H]1[....
10 3P5G - FUC C6 H12 O5 C[C@H]1[C@....
11 4N32 - 2F8 C9 H17 N O6 CC(=O)N[C@....
12 3P7H - MAL C12 H22 O11 C([C@@H]1[....
13 4N38 - NAG GAL n/a n/a
14 4N35 - NAG GAL BGC n/a n/a
15 3P5F - MAN C6 H12 O6 C([C@@H]1[....
16 5M62 - BGC C6 H12 O6 C([C@@H]1[....
50% Homology Family (12)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 272 families.
1 3P7G - MAN C6 H12 O6 C([C@@H]1[....
2 4N36 - 2F8 C9 H17 N O6 CC(=O)N[C@....
3 4N33 - NAG GAL BGC n/a n/a
4 4N37 - MMA C7 H14 O6 CO[C@@H]1[....
5 4N34 - 2F8 C9 H17 N O6 CC(=O)N[C@....
6 3P5E - MAN C6 H12 O6 C([C@@H]1[....
7 3P5D - MAN C6 H12 O6 C([C@@H]1[....
8 3P5G - FUC C6 H12 O5 C[C@H]1[C@....
9 4N32 - 2F8 C9 H17 N O6 CC(=O)N[C@....
10 4N38 - NAG GAL n/a n/a
11 4N35 - NAG GAL BGC n/a n/a
12 3P5F - MAN C6 H12 O6 C([C@@H]1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FUC; Similar ligands found: 9
No: Ligand ECFP6 Tc MDL keys Tc
1 G6D 1 1
2 XXR 1 1
3 FUL 1 1
4 FUC 1 1
5 RAM 1 1
6 FCA 1 1
7 RM4 1 1
8 FCB 1 1
9 FUF 0.424242 0.846154
Ligand no: 2; Ligand: GLA GAL FUC; Similar ligands found: 199
No: Ligand ECFP6 Tc MDL keys Tc
1 GAL GAL FUC 1 1
2 FUC GAL GLA 1 1
3 GLA GLA FUC 1 1
4 FUC GLA GLA 1 1
5 GLA GAL FUC 1 1
6 FUC GL0 A2G 0.691176 0.73913
7 A2G GLA FUC 0.691176 0.73913
8 A2G GAL FUC 0.691176 0.73913
9 NGA GAL FUC 0.691176 0.73913
10 FUC GLA A2G 0.691176 0.73913
11 FUC GAL A2G 0.691176 0.73913
12 FUC GAL NGA 0.671429 0.755556
13 FUC BGC GAL 0.666667 1
14 GLA MAN ABE 0.656716 0.944444
15 FUC GAL 0.627119 0.970588
16 BGC GLA GAL FUC 0.619718 1
17 BGB 0.56 0.790698
18 GAL NDG FUC 0.547945 0.73913
19 FUC NAG GAL 0.547945 0.73913
20 FUC NDG GAL 0.547945 0.73913
21 GAL NAG FUC 0.547945 0.73913
22 2M4 0.542373 0.970588
23 BGC BGC 0.542373 0.970588
24 MAN MAN 0.542373 0.970588
25 GLC GAL FUC 0.528571 1
26 LAT FUC 0.528571 1
27 FUC LAT 0.528571 1
28 FUC GAL GLC 0.528571 1
29 BGC GAL FUC 0.528571 1
30 GLA NAG GAL FUC 0.525 0.73913
31 GAL NAG GAL FUC 0.525 0.73913
32 MAN GLC 0.508197 0.970588
33 LB2 0.508197 0.970588
34 M3M 0.508197 0.970588
35 FUC NAG 0.507246 0.717391
36 MAG FUC GAL 0.506667 0.708333
37 BMA BMA MAN 0.5 0.942857
38 NAG GAL FUC 0.493506 0.73913
39 DR3 0.493506 0.73913
40 MAN MAN BMA 0.484848 0.970588
41 FUC BGC GAL NAG GAL 0.483146 0.73913
42 FUC BGC GAL NAG 0.482353 0.73913
43 GAL A2G 0.478261 0.755556
44 GAL NGA 0.478261 0.755556
45 A2G GAL 0.478261 0.755556
46 GLA GAL NAG FUC GAL GLC 0.478261 0.73913
47 GAL FUC 0.476923 0.970588
48 GLC FUC GAL FUC A2G 0.476744 0.723404
49 BGC FUC GAL FUC A2G 0.476744 0.723404
50 A2G GAL BGC FUC 0.471264 0.73913
51 GLC BGC BGC BGC 0.469697 0.970588
52 BGC BGC BGC GLC BGC BGC 0.469697 0.970588
53 BGC BGC BGC ASO BGC BGC ASO 0.469697 0.970588
54 BGC BGC BGC BGC BGC 0.469697 0.970588
55 GLC BGC BGC BGC BGC BGC BGC 0.469697 0.970588
56 BGC BGC BGC 0.469697 0.970588
57 MDM 0.46875 0.971429
58 GAL MBG 0.46875 0.971429
59 M13 0.46875 0.971429
60 NAG FUC 0.464789 0.695652
61 BMA MAN MAN 0.463768 0.970588
62 FUL GAL NAG 0.461538 0.73913
63 DR2 0.461538 0.73913
64 FUC GAL NDG 0.461538 0.73913
65 FUC GAL NAG 0.461538 0.73913
66 NDG GAL FUC 0.461538 0.73913
67 XYS GAL FUC 0.460526 0.971429
68 LAT 0.460317 0.970588
69 GAL BGC 0.460317 0.970588
70 GLA GAL 0.460317 0.970588
71 MAL MAL 0.460317 0.942857
72 MAL 0.460317 0.970588
73 GLC GAL 0.460317 0.970588
74 B2G 0.460317 0.970588
75 LBT 0.460317 0.970588
76 BMA GAL 0.460317 0.970588
77 MAB 0.460317 0.970588
78 CBK 0.460317 0.970588
79 CBI 0.460317 0.970588
80 GLA GLA 0.460317 0.970588
81 BMA BMA 0.460317 0.970588
82 BGC GLC 0.460317 0.970588
83 BGC BMA 0.460317 0.970588
84 GAL GLC 0.460317 0.970588
85 GLC BGC 0.460317 0.970588
86 N9S 0.460317 0.970588
87 BGC GAL 0.460317 0.970588
88 A2G GAL NAG FUC 0.454545 0.693878
89 TRE 0.454545 0.970588
90 GAL NGA A2G 0.453333 0.693878
91 FUC BHG 0.453333 0.790698
92 4YA 0.453333 0.790698
93 BHG FUC 0.453333 0.790698
94 MAN MAN MAN GLC 0.452055 0.970588
95 BGC BGC GLC 0.449275 0.970588
96 FUC NAG GLA GAL 0.448276 0.723404
97 NAG GAL FUC FUC A2G 0.444444 0.693878
98 BCW 0.444444 0.723404
99 GAL NDG FUC FUC 0.444444 0.723404
100 FUC GAL NAG FUC 0.444444 0.723404
101 GAL NAG FUC FUC 0.444444 0.723404
102 FUC NDG GAL FUC 0.444444 0.723404
103 FUC GAL NAG A2G FUC 0.444444 0.693878
104 BDZ 0.444444 0.723404
105 FUC GAL NDG FUC 0.444444 0.723404
106 FUC NAG GAL FUC 0.444444 0.723404
107 GLA MBG 0.444444 0.971429
108 GLA MMA ABE 0.441558 0.894737
109 BHE 0.441558 0.790698
110 BMA MAN 0.439394 0.888889
111 DOM 0.439394 0.916667
112 GAL MGC 0.43662 0.723404
113 NLC 0.43662 0.755556
114 NDG GAL 0.43662 0.755556
115 GAL NDG 0.43662 0.755556
116 U63 0.432836 0.868421
117 CTT 0.432836 0.970588
118 GAL GAL GAL 0.432836 0.970588
119 CEY 0.432836 0.970588
120 GLC BGC BGC 0.432836 0.970588
121 CE8 0.432836 0.970588
122 GLC BGC BGC BGC BGC BGC 0.432836 0.970588
123 BGC GLC GLC GLC GLC 0.432836 0.970588
124 BGC GLC GLC 0.432836 0.970588
125 CT3 0.432836 0.970588
126 GLC BGC GLC 0.432836 0.970588
127 MAN BMA BMA 0.432836 0.970588
128 BMA BMA BMA 0.432836 0.970588
129 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.432836 0.970588
130 MLR 0.432836 0.970588
131 GLC GLC GLC GLC GLC GLC GLC 0.432836 0.970588
132 GLC GLC BGC GLC GLC GLC GLC 0.432836 0.970588
133 CTR 0.432836 0.970588
134 BMA BMA BMA BMA BMA BMA 0.432836 0.970588
135 GLC GLC GLC GLC GLC 0.432836 0.970588
136 BGC GLC GLC GLC 0.432836 0.970588
137 MAN BMA BMA BMA BMA 0.432836 0.970588
138 CEX 0.432836 0.970588
139 B4G 0.432836 0.970588
140 BGC GLC GLC GLC GLC GLC GLC 0.432836 0.970588
141 GLC GAL GAL 0.432836 0.970588
142 BMA MAN BMA 0.432836 0.970588
143 GLA GAL GLC 0.432836 0.970588
144 BMA BMA BMA BMA BMA 0.432836 0.970588
145 MTT 0.432836 0.970588
146 GLC GLC BGC 0.432836 0.970588
147 BGC BGC BGC BGC BGC BGC 0.432836 0.970588
148 CE5 0.432836 0.970588
149 GLC GLC GLC GLC GLC GLC GLC GLC 0.432836 0.970588
150 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.432836 0.970588
151 BGC BGC BGC GLC 0.432836 0.970588
152 MT7 0.432836 0.970588
153 CE6 0.432836 0.970588
154 DXI 0.432836 0.970588
155 MAN MAN BMA BMA BMA BMA 0.432836 0.970588
156 GLC BGC BGC BGC BGC 0.432836 0.970588
157 FUC GAL NAG GAL FUC 0.431818 0.723404
158 EAG RAM RAM GLC RAM NAG RAM RAM GLC RAM 0.430108 0.68
159 CGC 0.428571 0.914286
160 GLA EGA 0.426471 0.971429
161 GAL GAL SO4 0.424658 0.6875
162 GLC GAL NAG GAL FUC A2G 0.424242 0.693878
163 A2G GAL NAG FUC GAL GLC 0.424242 0.693878
164 DR5 0.424242 0.971429
165 MMA MAN 0.424242 0.971429
166 FUC GAL NAG GAL BGC 0.423913 0.73913
167 GLA GAL GAL 0.422535 0.970588
168 GLA GAL BGC 0.422535 0.970588
169 LAT GLA 0.421875 0.970588
170 BGA 0.417582 0.618182
171 GAL NAG MAN 0.4125 0.755556
172 MAN NAG GAL 0.4125 0.755556
173 FUC GAL MAG FUC 0.409639 0.708333
174 MAN BMA BMA BMA BMA BMA 0.408451 0.942857
175 BMA BMA BMA BMA BMA BMA MAN 0.408451 0.942857
176 ABD 0.406977 0.772727
177 GLC GAL NAG GAL FUC FUC 0.40625 0.723404
178 BGC GAL NAG GAL FUC FUC 0.40625 0.723404
179 NOY BGC 0.405797 0.733333
180 AIG FUC 0.405063 0.66
181 GLA GAL NAG 0.405063 0.755556
182 MAN BMA NAG 0.405063 0.755556
183 NAG GAL GAL 0.405063 0.755556
184 GLC G6D ACI GLC 0.404494 0.809524
185 GLC ACI GLD GLC 0.404494 0.809524
186 GLC ACI G6D BGC 0.404494 0.809524
187 GLC G6D ADH GLC 0.404494 0.809524
188 RZM 0.402985 0.673913
189 T6P 0.402985 0.75
190 GAL LOG 0.402597 0.607143
191 MAN MAN MAN MAN 0.402597 0.970588
192 LOG GAL 0.402597 0.607143
193 MAN MAN BMA MAN 0.402597 0.970588
194 BGC OXZ 0.4 0.653061
195 BGC BGC BGC BGC BGC BGC BGC BGC 0.4 0.970588
196 GLC GLC GLC GLC 0.4 0.970588
197 MAN MNM 0.4 0.733333
198 BGC BGC BGC BGC 0.4 0.970588
199 NAG BMA 0.4 0.673469
Ligand no: 3; Ligand: GLA GLA FUC; Similar ligands found: 199
No: Ligand ECFP6 Tc MDL keys Tc
1 GAL GAL FUC 1 1
2 FUC GAL GLA 1 1
3 GLA GLA FUC 1 1
4 FUC GLA GLA 1 1
5 GLA GAL FUC 1 1
6 FUC GL0 A2G 0.691176 0.73913
7 A2G GLA FUC 0.691176 0.73913
8 A2G GAL FUC 0.691176 0.73913
9 NGA GAL FUC 0.691176 0.73913
10 FUC GLA A2G 0.691176 0.73913
11 FUC GAL A2G 0.691176 0.73913
12 FUC GAL NGA 0.671429 0.755556
13 FUC BGC GAL 0.666667 1
14 GLA MAN ABE 0.656716 0.944444
15 FUC GAL 0.627119 0.970588
16 BGC GLA GAL FUC 0.619718 1
17 BGB 0.56 0.790698
18 GAL NDG FUC 0.547945 0.73913
19 FUC NAG GAL 0.547945 0.73913
20 FUC NDG GAL 0.547945 0.73913
21 GAL NAG FUC 0.547945 0.73913
22 2M4 0.542373 0.970588
23 BGC BGC 0.542373 0.970588
24 MAN MAN 0.542373 0.970588
25 GLC GAL FUC 0.528571 1
26 LAT FUC 0.528571 1
27 FUC LAT 0.528571 1
28 FUC GAL GLC 0.528571 1
29 BGC GAL FUC 0.528571 1
30 GLA NAG GAL FUC 0.525 0.73913
31 GAL NAG GAL FUC 0.525 0.73913
32 MAN GLC 0.508197 0.970588
33 LB2 0.508197 0.970588
34 M3M 0.508197 0.970588
35 FUC NAG 0.507246 0.717391
36 MAG FUC GAL 0.506667 0.708333
37 BMA BMA MAN 0.5 0.942857
38 NAG GAL FUC 0.493506 0.73913
39 DR3 0.493506 0.73913
40 MAN MAN BMA 0.484848 0.970588
41 FUC BGC GAL NAG GAL 0.483146 0.73913
42 FUC BGC GAL NAG 0.482353 0.73913
43 GAL A2G 0.478261 0.755556
44 GAL NGA 0.478261 0.755556
45 A2G GAL 0.478261 0.755556
46 GLA GAL NAG FUC GAL GLC 0.478261 0.73913
47 GAL FUC 0.476923 0.970588
48 GLC FUC GAL FUC A2G 0.476744 0.723404
49 BGC FUC GAL FUC A2G 0.476744 0.723404
50 A2G GAL BGC FUC 0.471264 0.73913
51 GLC BGC BGC BGC 0.469697 0.970588
52 BGC BGC BGC GLC BGC BGC 0.469697 0.970588
53 BGC BGC BGC ASO BGC BGC ASO 0.469697 0.970588
54 BGC BGC BGC BGC BGC 0.469697 0.970588
55 GLC BGC BGC BGC BGC BGC BGC 0.469697 0.970588
56 BGC BGC BGC 0.469697 0.970588
57 MDM 0.46875 0.971429
58 GAL MBG 0.46875 0.971429
59 M13 0.46875 0.971429
60 NAG FUC 0.464789 0.695652
61 BMA MAN MAN 0.463768 0.970588
62 FUL GAL NAG 0.461538 0.73913
63 DR2 0.461538 0.73913
64 FUC GAL NDG 0.461538 0.73913
65 FUC GAL NAG 0.461538 0.73913
66 NDG GAL FUC 0.461538 0.73913
67 XYS GAL FUC 0.460526 0.971429
68 LAT 0.460317 0.970588
69 GAL BGC 0.460317 0.970588
70 GLA GAL 0.460317 0.970588
71 MAL MAL 0.460317 0.942857
72 MAL 0.460317 0.970588
73 GLC GAL 0.460317 0.970588
74 B2G 0.460317 0.970588
75 LBT 0.460317 0.970588
76 BMA GAL 0.460317 0.970588
77 MAB 0.460317 0.970588
78 CBK 0.460317 0.970588
79 CBI 0.460317 0.970588
80 GLA GLA 0.460317 0.970588
81 BMA BMA 0.460317 0.970588
82 BGC GLC 0.460317 0.970588
83 BGC BMA 0.460317 0.970588
84 GAL GLC 0.460317 0.970588
85 GLC BGC 0.460317 0.970588
86 N9S 0.460317 0.970588
87 BGC GAL 0.460317 0.970588
88 A2G GAL NAG FUC 0.454545 0.693878
89 TRE 0.454545 0.970588
90 GAL NGA A2G 0.453333 0.693878
91 FUC BHG 0.453333 0.790698
92 4YA 0.453333 0.790698
93 BHG FUC 0.453333 0.790698
94 MAN MAN MAN GLC 0.452055 0.970588
95 BGC BGC GLC 0.449275 0.970588
96 FUC NAG GLA GAL 0.448276 0.723404
97 NAG GAL FUC FUC A2G 0.444444 0.693878
98 BCW 0.444444 0.723404
99 GAL NDG FUC FUC 0.444444 0.723404
100 FUC GAL NAG FUC 0.444444 0.723404
101 GAL NAG FUC FUC 0.444444 0.723404
102 FUC NDG GAL FUC 0.444444 0.723404
103 FUC GAL NAG A2G FUC 0.444444 0.693878
104 BDZ 0.444444 0.723404
105 FUC GAL NDG FUC 0.444444 0.723404
106 FUC NAG GAL FUC 0.444444 0.723404
107 GLA MBG 0.444444 0.971429
108 GLA MMA ABE 0.441558 0.894737
109 BHE 0.441558 0.790698
110 BMA MAN 0.439394 0.888889
111 DOM 0.439394 0.916667
112 GAL MGC 0.43662 0.723404
113 NLC 0.43662 0.755556
114 NDG GAL 0.43662 0.755556
115 GAL NDG 0.43662 0.755556
116 U63 0.432836 0.868421
117 CTT 0.432836 0.970588
118 GAL GAL GAL 0.432836 0.970588
119 CEY 0.432836 0.970588
120 GLC BGC BGC 0.432836 0.970588
121 CE8 0.432836 0.970588
122 GLC BGC BGC BGC BGC BGC 0.432836 0.970588
123 BGC GLC GLC GLC GLC 0.432836 0.970588
124 BGC GLC GLC 0.432836 0.970588
125 CT3 0.432836 0.970588
126 GLC BGC GLC 0.432836 0.970588
127 MAN BMA BMA 0.432836 0.970588
128 BMA BMA BMA 0.432836 0.970588
129 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.432836 0.970588
130 MLR 0.432836 0.970588
131 GLC GLC GLC GLC GLC GLC GLC 0.432836 0.970588
132 GLC GLC BGC GLC GLC GLC GLC 0.432836 0.970588
133 CTR 0.432836 0.970588
134 BMA BMA BMA BMA BMA BMA 0.432836 0.970588
135 GLC GLC GLC GLC GLC 0.432836 0.970588
136 BGC GLC GLC GLC 0.432836 0.970588
137 MAN BMA BMA BMA BMA 0.432836 0.970588
138 CEX 0.432836 0.970588
139 B4G 0.432836 0.970588
140 BGC GLC GLC GLC GLC GLC GLC 0.432836 0.970588
141 GLC GAL GAL 0.432836 0.970588
142 BMA MAN BMA 0.432836 0.970588
143 GLA GAL GLC 0.432836 0.970588
144 BMA BMA BMA BMA BMA 0.432836 0.970588
145 MTT 0.432836 0.970588
146 GLC GLC BGC 0.432836 0.970588
147 BGC BGC BGC BGC BGC BGC 0.432836 0.970588
148 CE5 0.432836 0.970588
149 GLC GLC GLC GLC GLC GLC GLC GLC 0.432836 0.970588
150 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.432836 0.970588
151 BGC BGC BGC GLC 0.432836 0.970588
152 MT7 0.432836 0.970588
153 CE6 0.432836 0.970588
154 DXI 0.432836 0.970588
155 MAN MAN BMA BMA BMA BMA 0.432836 0.970588
156 GLC BGC BGC BGC BGC 0.432836 0.970588
157 FUC GAL NAG GAL FUC 0.431818 0.723404
158 EAG RAM RAM GLC RAM NAG RAM RAM GLC RAM 0.430108 0.68
159 CGC 0.428571 0.914286
160 GLA EGA 0.426471 0.971429
161 GAL GAL SO4 0.424658 0.6875
162 GLC GAL NAG GAL FUC A2G 0.424242 0.693878
163 A2G GAL NAG FUC GAL GLC 0.424242 0.693878
164 DR5 0.424242 0.971429
165 MMA MAN 0.424242 0.971429
166 FUC GAL NAG GAL BGC 0.423913 0.73913
167 GLA GAL GAL 0.422535 0.970588
168 GLA GAL BGC 0.422535 0.970588
169 LAT GLA 0.421875 0.970588
170 BGA 0.417582 0.618182
171 GAL NAG MAN 0.4125 0.755556
172 MAN NAG GAL 0.4125 0.755556
173 FUC GAL MAG FUC 0.409639 0.708333
174 MAN BMA BMA BMA BMA BMA 0.408451 0.942857
175 BMA BMA BMA BMA BMA BMA MAN 0.408451 0.942857
176 ABD 0.406977 0.772727
177 GLC GAL NAG GAL FUC FUC 0.40625 0.723404
178 BGC GAL NAG GAL FUC FUC 0.40625 0.723404
179 NOY BGC 0.405797 0.733333
180 AIG FUC 0.405063 0.66
181 GLA GAL NAG 0.405063 0.755556
182 MAN BMA NAG 0.405063 0.755556
183 NAG GAL GAL 0.405063 0.755556
184 GLC G6D ACI GLC 0.404494 0.809524
185 GLC ACI GLD GLC 0.404494 0.809524
186 GLC ACI G6D BGC 0.404494 0.809524
187 GLC G6D ADH GLC 0.404494 0.809524
188 RZM 0.402985 0.673913
189 T6P 0.402985 0.75
190 GAL LOG 0.402597 0.607143
191 MAN MAN MAN MAN 0.402597 0.970588
192 LOG GAL 0.402597 0.607143
193 MAN MAN BMA MAN 0.402597 0.970588
194 BGC OXZ 0.4 0.653061
195 BGC BGC BGC BGC BGC BGC BGC BGC 0.4 0.970588
196 GLC GLC GLC GLC 0.4 0.970588
197 MAN MNM 0.4 0.733333
198 BGC BGC BGC BGC 0.4 0.970588
199 NAG BMA 0.4 0.673469
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3P7G; Ligand: MAN; Similar sites found: 66
This union binding pocket(no: 1) in the query (biounit: 3p7g.bio2) has 10 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2QX0 APC 0.002523 0.44543 None
2 3CEV ARG 0.03258 0.40699 None
3 4MN3 ACE PHE ALA TYR M3L SER NH2 0.01883 0.40515 None
4 3S2Y FMN 0.02103 0.40076 None
5 2FZH DH1 0.02326 0.43577 2.05479
6 1I0S FMN 0.00698 0.43286 2.05479
7 1I0S NAP 0.009369 0.43286 2.05479
8 2IMF TOM 0.02204 0.43242 2.05479
9 2IMF GSH 0.02204 0.43242 2.05479
10 1TMM HHR 0.00777 0.4302 2.05479
11 1TMM APC 0.008186 0.4302 2.05479
12 2WOJ ADP ALF 0.01951 0.41272 2.05479
13 5J1J ANP 0.03109 0.40022 2.05479
14 4QVB F42 0.00656 0.42232 2.73973
15 5BVA FAD 0.03839 0.41137 2.73973
16 3ZQ6 ADP ALF 0.02054 0.4107 2.73973
17 5N0F 7K2 0.0252 0.40208 2.73973
18 3E1T FAD 0.009982 0.44473 3.42466
19 1YOA FAD 0.01809 0.4222 3.42466
20 2NYR SVR 0.02171 0.41504 3.42466
21 1TKK ALA GLU 0.02007 0.40086 3.42466
22 5EPK 5R0 PHE ALA LEU ELY 5R5 0.02234 0.40188 3.63636
23 4M38 SAH 0.01139 0.42931 4.10959
24 4M37 SAH 0.01173 0.42212 4.10959
25 1XVB BHL 0.0248 0.41259 4.10959
26 1USF NAP 0.01843 0.40787 4.10959
27 1USF FMN 0.01597 0.40787 4.10959
28 1LSZ NDG NAG NAG NAG 0.008594 0.40112 4.10959
29 1KRH FAD 0.03038 0.40516 4.79452
30 3UR0 SVR 0.005954 0.46859 5.47945
31 2IFW ACE PHE LYS PHE PSA LEU AAR 0.02738 0.42464 5.47945
32 2OAT PFM 0.01686 0.41407 5.47945
33 5E9X 5LA 0.04142 0.41047 5.47945
34 4YHB FAD 0.03598 0.40324 5.47945
35 5TCI 79V 0.00126 0.47775 6.16438
36 5ETR 5RW 0.007149 0.44033 6.16438
37 5ETR APC 0.007149 0.44033 6.16438
38 5BUK FAD 0.02544 0.41232 6.16438
39 3MJY FMN 0.03334 0.40291 6.16438
40 3MJY IJZ 0.03334 0.40291 6.16438
41 3R5Z F42 0.02828 0.41073 6.2069
42 4FZV SAM 0.01481 0.41032 7.53425
43 5NVX 4YY 0.007319 0.42942 7.69231
44 4W9F 3JU 0.006375 0.4264 7.69231
45 4B9K TG0 0.00859 0.41848 7.69231
46 5WXH ALA ARG THR M3L GLN THR ALA 0.01581 0.40456 7.93651
47 5ND5 TPP 0.01898 0.42003 8.21918
48 1ECC PCP 0.0193 0.40703 8.21918
49 1T0I FMN 0.01396 0.40263 8.21918
50 2D0N PRO SER ILE ASP ARG SER THR LYS PRO 0.0083 0.41268 8.47458
51 4BKS X6C 0.005012 0.42611 8.65385
52 4BKJ STI 0.03309 0.40851 8.90411
53 4QLX FMN 0.01064 0.43308 10.9589
54 2PAV ATP 0.02213 0.41511 11.6438
55 2J83 BAT 0.03613 0.40446 12.3288
56 1BB6 UMG 0.007245 0.41569 13.1783
57 3PAK MAN 0.02248 0.43319 21.9178
58 1FKB RAP 0.02235 0.42305 25.2336
59 2GGX NPJ 0.00000003308 0.70082 35.6164
60 1G1T SIA GAL MAG FUC 0.0000123 0.56445 36.3014
61 1PWB GLC 0.00000001271 0.59009 36.9863
62 1PWB GLC GLC 0.0000000133 0.58908 36.9863
63 2VUZ NAG BMA NAG MAN MAN NAG NAG 0.0000003541 0.65444 40.3101
64 4DN8 BMA 0.000000325 0.57292 40.411
65 5JQ1 ZPF 0.00000004258 0.69193 40.6897
66 5KTI TRE 6X6 0.00000000234 0.75224 46.5753
Pocket No.: 2; Query (leader) PDB : 3P7G; Ligand: MAN; Similar sites found: 62
This union binding pocket(no: 2) in the query (biounit: 3p7g.bio4) has 13 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4ITU NAI 0.02941 0.4153 None
2 4ITU 1HS 0.04148 0.4153 None
3 2CYE COA 0.03072 0.40312 None
4 2V1O COA 0.03559 0.40178 None
5 4ISK UMP 0.01602 0.40103 None
6 5C79 PBU 0.005416 0.42085 2.05479
7 4LOK 1YD 0.03715 0.41496 2.05479
8 2Z7R STU 0.02614 0.40382 2.05479
9 2MAS PIR 0.01167 0.41396 3.42466
10 5UOX 8GY 0.0217 0.40949 3.42466
11 2FXV 5GP 0.03131 0.4032 3.42466
12 4CNG SAH 0.04181 0.40079 3.42466
13 4JAW NGT GAL 0.02004 0.40053 3.42466
14 2EV9 SKM 0.03708 0.40873 4.10959
15 2EV9 NAP 0.03708 0.40873 4.10959
16 1RX0 FAD 0.04258 0.40843 4.10959
17 3KRL KRL 0.02239 0.4063 4.10959
18 4WNP 3RJ 0.01418 0.40569 4.10959
19 1ICP FMN 0.0386 0.40439 4.10959
20 4HKP TKW 0.02936 0.40283 4.10959
21 5C5H 4YB 0.03814 0.40171 4.10959
22 2AAZ UMP 0.01918 0.40158 4.10959
23 4H6Q TFB 0.04314 0.40051 4.10959
24 4H6Q FAD 0.04153 0.40021 4.10959
25 4YZC STU 0.04463 0.40603 4.79452
26 5CKW ANP 0.0132 0.40579 4.79452
27 4EJN 0R4 0.02667 0.40119 4.79452
28 2YIC TPP 0.01976 0.4202 5.47945
29 3AAQ ARU 0.0327 0.41691 5.47945
30 1QM5 GLC GLC GLC PO4 SGC GLC 0.03347 0.41401 5.47945
31 1QM5 PLP 0.04807 0.41401 5.47945
32 1CJW COT 0.03323 0.4081 5.47945
33 1LBF 137 0.03098 0.40707 5.47945
34 3APT FAD 0.02002 0.41851 6.16438
35 2Q3O FMN 0.02133 0.41351 6.16438
36 4O67 1SY 0.03142 0.40456 6.16438
37 4TMC HBA 0.01578 0.41998 6.84932
38 1F28 UMP 0.009053 0.41871 6.84932
39 4EHU ANP 0.02162 0.41228 6.84932
40 4OTH DRN 0.02057 0.40902 6.84932
41 5JBE GLC GLC GLC GLC GLC 0.04955 0.40477 6.84932
42 3AI7 TPP 0.03331 0.40358 6.84932
43 4EIL UMP 0.01783 0.40112 6.84932
44 3MKN DNB 0.009954 0.41719 7.53425
45 4IJP 1EH 0.01462 0.41682 7.53425
46 4GJ3 0XP 0.03941 0.40448 7.53425
47 4W9H 3JF 0.01494 0.40453 7.69231
48 5LXM ADP 0.01385 0.41079 7.89474
49 5G1X ADP 0.01192 0.41441 7.93651
50 5L8L ADP 0.01226 0.40775 8.21918
51 2X2M X2M 0.01949 0.41017 8.90411
52 1D01 ACE MET LEU SER VAL GLU GLU GLU GLY 0.02548 0.40245 8.90411
53 1VYP FMN 0.03687 0.4016 8.90411
54 1VYP TNF 0.03482 0.4016 8.90411
55 1RC0 KT5 0.04522 0.40292 9.58904
56 1OLT SAM 0.01856 0.40882 10.274
57 1QSC ACE TYR PRO ILE GLN GLU THR 0.02043 0.4028 10.9589
58 5EYK 5U5 0.01614 0.4221 16.9492
59 3B2Q ATP 0.01317 0.42371 17.1233
60 4C2V YJA 0.01135 0.43253 18.1818
61 4C2W ANP 0.01065 0.41032 19.2308
62 2HY0 306 0.01026 0.41326 19.863
Pocket No.: 3; Query (leader) PDB : 3P7G; Ligand: MAN; Similar sites found: 46
This union binding pocket(no: 3) in the query (biounit: 3p7g.bio1) has 9 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3GFS FMN 0.01298 0.40994 None
2 5HGZ ACO 0.03409 0.40822 2.05479
3 3AR5 TM1 0.007476 0.44843 2.73973
4 3LM9 ADP 0.0186 0.42779 2.73973
5 1YKF NAP 0.03266 0.41623 2.73973
6 2VH6 GSV 0.02353 0.41478 2.73973
7 3GD4 NAD 0.02581 0.44925 3.42466
8 3VBK COA 0.0159 0.42816 3.42466
9 3GD4 FAD 0.02628 0.42685 3.42466
10 2X3J X3J 0.0149 0.41825 3.42466
11 2X3J ATP 0.01046 0.41825 3.42466
12 1NFU RRP 0.01259 0.41798 3.42466
13 1LC3 NAD 0.01593 0.41437 3.42466
14 1PQ7 ARG 0.02037 0.40863 3.42466
15 2OQ5 BEN 0.0128 0.40447 3.42466
16 5WB6 9ZM 0.03876 0.40292 3.42466
17 5Q0F 9FA 0.03604 0.40254 3.42466
18 4JAW GAL NGT 0.01142 0.40151 3.42466
19 2A5F NAD 0.006352 0.41872 4.10959
20 2P3T 993 0.02013 0.41589 4.10959
21 1J17 ZEN 0.01954 0.40924 4.10959
22 2BDG PBZ 0.01386 0.40186 4.10959
23 1RTF BEN 0.00666 0.41928 4.79452
24 4PZV J1D 0.01585 0.41417 4.79452
25 1DQN IMU 0.00758 0.41219 4.79452
26 4MIG G3F 0.0337 0.40883 4.79452
27 4EDK GTP 0.01519 0.40266 4.79452
28 1O5E 132 0.02046 0.40738 5.26316
29 3UTU 1TS 0.03126 0.41876 5.47945
30 2ANM CDO 0.02641 0.41118 5.47945
31 2ANK N12 0.02288 0.40981 5.47945
32 1TMT DPN PRO ARG 0.02601 0.40832 5.47945
33 1EB1 ZAL PRO MMO 0.03765 0.407 5.47945
34 1D9I 00P 0.04903 0.4025 5.47945
35 5U97 PIT 0.02206 0.40113 5.47945
36 4O97 NTX 0.02525 0.41145 6.16438
37 4AK7 47N 0.007398 0.40644 6.16438
38 2YFT DQR 0.02341 0.40028 6.16438
39 2C29 NAP 0.04776 0.41018 6.84932
40 2PKA BEN 0.01042 0.41688 7.5
41 4YDD MGD 0.04417 0.43347 8.90411
42 4YDD MD1 0.04417 0.43347 8.90411
43 1RLJ FMN 0.00984 0.40333 10.7914
44 4QLX KTC 0.01563 0.43438 10.9589
45 4MTI 2DX 0.01545 0.41065 13.0137
46 1FIW PBZ 0.0203 0.40376 31.8182
Pocket No.: 4; Query (leader) PDB : 3P7G; Ligand: MAN; Similar sites found: 9
This union binding pocket(no: 4) in the query (biounit: 3p7g.bio3) has 10 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1GJC 130 0.02051 0.41811 2.05479
2 3PBB PBD 0.03204 0.40146 3.42466
3 1NLU IVA PHI TYB 0.01254 0.40393 4.10959
4 1EWY FAD 0.02105 0.41471 4.79452
5 3H4L ANP 0.01 0.42596 6.16438
6 5UAO FAD 0.03876 0.4045 7.53425
7 2CER PGI 0.04519 0.41226 10.274
8 4W8B GLC BGC BGC XYS BGC XYS XYS GAL 0.007529 0.42002 11.6438
9 3VZS NAP 0.04133 0.40557 12.3288
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