Receptor
PDB id Resolution Class Description Source Keywords
3PP0 2.25 Å EC: 2.7.10.1 CRYSTAL STRUCTURE OF THE KINASE DOMAIN OF HUMAN HER2 (ERBB2) HOMO SAPIENS KINASE DOMAIN ANTI-ONCOGENE ATP-BINDING CELL CYCLE DISEAMUTATION GLYCOPROTEIN MEMBRANE NUCLEOTIDE-BINDING PHOSPHOPROTEIN RECEPTOR SECRETED TRANSFERASE TRANSMEMBRTYROSINE-PROTEIN KINASE TYROSINE KINASE INHIBITOR TRANSFETRANSFERASE INHIBITOR COMPLEX
Ref.: STRUCTURAL ANALYSIS OF THE MECHANISM OF INHIBITION ALLOSTERIC ACTIVATION OF THE KINASE DOMAIN OF HER2 J.BIOL.CHEM. V. 286 18756 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
03Q A:1;
B:2;
Valid;
Valid;
none;
none;
ic50 = 11 nM
493.866 C22 H19 Cl F3 N5 O3 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3PP0 2.25 Å EC: 2.7.10.1 CRYSTAL STRUCTURE OF THE KINASE DOMAIN OF HUMAN HER2 (ERBB2) HOMO SAPIENS KINASE DOMAIN ANTI-ONCOGENE ATP-BINDING CELL CYCLE DISEAMUTATION GLYCOPROTEIN MEMBRANE NUCLEOTIDE-BINDING PHOSPHOPROTEIN RECEPTOR SECRETED TRANSFERASE TRANSMEMBRTYROSINE-PROTEIN KINASE TYROSINE KINASE INHIBITOR TRANSFETRANSFERASE INHIBITOR COMPLEX
Ref.: STRUCTURAL ANALYSIS OF THE MECHANISM OF INHIBITION ALLOSTERIC ACTIVATION OF THE KINASE DOMAIN OF HER2 J.BIOL.CHEM. V. 286 18756 2011
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 31 families.
1 3PP0 ic50 = 11 nM 03Q C22 H19 Cl F3 N5 O3 c1cc(cc(c1....
70% Homology Family (23)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 16 families.
1 3PP0 ic50 = 11 nM 03Q C22 H19 Cl F3 N5 O3 c1cc(cc(c1....
2 3W32 ic50 = 75 nM W32 C25 H23 Cl F3 N5 O4 S CS(=O)(=O)....
3 5CAU Ki = 1.6 nM 4ZR C21 H25 F4 N7 O2 C[C@H](c1n....
4 5D41 ic50 = 0.024 uM 57N C19 H15 N3 O2 S c1ccc(cc1)....
5 4I22 - IRE C22 H24 Cl F N4 O3 COc1cc2c(c....
6 2ITV - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
7 3POZ ic50 = 23 nM 03P C26 H25 Cl F3 N5 O3 CC(C)(CC(=....
8 5HCY Ki = 1.2 nM 60D C26 H30 N8 O4 S CC(C)n1cc(....
9 5CAP Ki = 52 nM 4ZH C19 H26 N6 O3 S Cc1nc2cnc(....
10 3W33 ic50 = 36 nM W19 C25 H22 Cl N5 O3 S c1cc(c2ccs....
11 2ITN - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
12 4RJ8 Ki = 17 nM 3QS C22 H28 N6 O COC1CCN(CC....
13 5CAS Ki = 1.4 nM 4ZQ C21 H25 F4 N7 O2 C[C@H](c1n....
14 3VJN - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
15 3UG2 Kd = 5.6 nM IRE C22 H24 Cl F N4 O3 COc1cc2c(c....
16 5CNN - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
17 5CAQ Ki = 2.7 nM 4ZJ C20 H26 F N7 O Cc1nc2cnc(....
18 2RGP ic50 = 0.3 uM HYZ C24 H27 F N8 c1cc(cc(c1....
19 5UGA Ki = 161 nM 8BM C25 H35 N9 O CC(C)n1cnc....
20 5CNO - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
21 5C8N Ki = 492 nM 4YX C22 H32 N8 O Cc1nc2cnc(....
22 1XKK Ki = 3 nM FMM C29 H26 Cl F N4 O4 S CS(=O)(=O)....
23 3BEL ic50 = 0.014 uM POX C22 H22 F N7 O2 COCCO/N=C/....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 7 families.
1 3PP0 ic50 = 11 nM 03Q C22 H19 Cl F3 N5 O3 c1cc(cc(c1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 03Q; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 03Q 1 1
2 03P 0.495868 0.814815
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3PP0; Ligand: 03Q; Similar sites found: 280
This union binding pocket(no: 1) in the query (biounit: 3pp0.bio1) has 27 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3LQV ADE 0.0141 0.41893 None
2 5I35 ANP 0.00008064 0.43319 1.47929
3 1PK8 ATP 0.001793 0.41193 1.47929
4 4BG4 ADP 0.0005417 0.40155 1.77515
5 4ANW O92 0.001194 0.43043 2.07101
6 5NCY 8TK 0.002653 0.41364 2.07101
7 2PUL ACP 0.0005564 0.4022 2.07101
8 4OCJ NDG 0.004092 0.41477 2.36686
9 3ZJX BOG 0.001491 0.47708 2.42215
10 5IQD GNP 0.006899 0.40427 2.62295
11 5IQD RIO 0.007333 0.40427 2.62295
12 2V58 LZJ 0.007506 0.40985 2.66272
13 2YNE NHW 0.02636 0.40808 2.66272
14 2YNE YNE 0.02636 0.40808 2.66272
15 5TUF FAD 0.01382 0.40805 2.66272
16 5TUF TDC 0.01557 0.4078 2.66272
17 5D3U TRP 0.03469 0.40227 2.66272
18 1GSA ADP 0.000262 0.43666 2.8481
19 4B2Z P5S 0.005796 0.40959 2.95858
20 5EOO CIT 0.03331 0.40361 3.01887
21 3VPC ADP 0.0007072 0.41461 3.19149
22 4B0T ADP 0.002336 0.40776 3.25444
23 5K2M ADP 0.002383 0.40342 3.77358
24 3SHR CMP 0.009284 0.42333 3.84615
25 5MW8 ATP 0.0009029 0.41606 4.14201
26 3W0O HY0 0.004804 0.40327 4.14201
27 3W0O ADP 0.004804 0.40327 4.14201
28 3UDZ ADP 0.0001649 0.42589 4.43787
29 4AXD ANP 0.003315 0.41855 4.43787
30 1C1X HFA 0.0106 0.4164 4.50704
31 3TM0 B31 0.005435 0.405 4.56274
32 3TM0 ANP 0.005062 0.405 4.56274
33 1BW9 PPY 0.01374 0.40719 4.73373
34 1I7L ATP 0.002156 0.40434 4.85437
35 4GYI ADP 0.00007173 0.42284 5.02959
36 1TQP ATP 0.0007224 0.42386 5.31915
37 4WW7 AMP 0.0001665 0.44113 5.34759
38 3B6R ADP 0.00046 0.47211 5.6213
39 3B6R CRN 0.001669 0.43697 5.6213
40 5LXT GTP 0.009325 0.42332 5.6213
41 4ZS4 ATP 0.0004048 0.41446 5.86319
42 3TDV GDP 0.0005281 0.40985 5.88235
43 4AZW ATP 0.00157 0.40241 5.91716
44 3RE4 TO1 0.00005933 0.41355 6.20155
45 4IX4 ADP 0.00004649 0.4552 6.21302
46 5LIA 6XN 0.006695 0.42731 6.50888
47 4KU7 PCG 0.004855 0.43288 6.53595
48 4C5N ACP 0.00707 0.40034 7.24638
49 2PYW ADP 0.0002601 0.42784 7.39645
50 4F9C 0SX 0.00000002753 0.53787 7.69231
51 3DNT ATP 0.001514 0.4119 7.69231
52 4Q5H ANP 0.00127 0.44732 8.33333
53 4OUC 5ID 0.000003302 0.46742 8.87574
54 5CKW ANP 0.00002526 0.43 8.87574
55 3T4L ZEA 0.0002516 0.41482 8.88889
56 2I0D MUT 0.0134 0.41263 9.09091
57 4CYI ATP 0.0001161 0.4385 9.1716
58 1IA9 ANP 0.0001871 0.42746 9.1716
59 5M06 ADP 0.000009407 0.44378 9.42029
60 1ZTH ADP 0.000006205 0.44082 10.0775
61 1ZP9 ATP 0.00002467 0.43712 10.0775
62 4R78 AMP 0.000008572 0.43769 10.355
63 5A89 FMN 0.003539 0.42268 12.8205
64 5A89 ADP 0.003539 0.42268 12.8205
65 4UX9 ANP 0.0000000608 0.55334 13.3136
66 4IZY 1J2 0.00001173 0.471 13.6095
67 5AWM ANP 0.0000000004208 0.55047 13.9053
68 4IJP 1EH 0.0000002116 0.53503 14.2012
69 5EFQ ADP 0.0000004954 0.5074 14.2012
70 4LRJ ANP 0.0001305 0.42107 14.2012
71 4NST ADP 0.00000036 0.51231 14.497
72 5BVE 4VG 0.00000001805 0.66729 15.3846
73 4QTB 38Z 0.000001461 0.54229 15.9763
74 3Q60 ATP 0.0002072 0.41522 15.9763
75 4OAV ACP 0.0000006256 0.4973 16.568
76 4JR7 GNP 0.00000005793 0.53806 16.8639
77 5DMZ ADP 0.000001563 0.49351 16.8639
78 4O1P ANP 0.000001036 0.4979 17.4556
79 3VPB ADP 0.001054 0.42124 17.8571
80 3HMO STU 0.000001132 0.4878 19.2982
81 5GZ9 ANP 0.0000001481 0.55521 19.3443
82 3GNI ATP 0.000001127 0.50816 20.1183
83 2ZV2 609 0.00000009835 0.67029 20.8054
84 4XH0 ADP 0.000005361 0.41372 21.0059
85 5N87 N66 0.00000121 0.55717 21.0863
86 4JDI ANP 0.000008126 0.4815 21.5976
87 5MY8 RXZ 0.00003752 0.4773 21.5976
88 4CRL C1I 0.000008462 0.5192 21.9212
89 4Y8D 49J 0.00000002472 0.54993 23.0769
90 4Y0X ADP 0.0001714 0.42052 23.0769
91 1ZY5 ANP 0.0001638 0.41476 23.1023
92 4D2S DYK 0.0000005607 0.47722 23.2394
93 1Q8Y ADP 0.0000003364 0.52916 23.8606
94 1Q8Y ADE 0.0000027 0.43816 23.8606
95 3FC2 IBI 0.02113 0.40442 23.8806
96 5LI1 ANP 0.00000008691 0.55659 24.2604
97 4DC2 ADE 0.000000179 0.44207 24.2604
98 5LI9 ACP 0.00001846 0.5247 24.2857
99 4A4X JUP 0.00001184 0.50202 24.3728
100 2WU6 DKI 0.0000001964 0.55153 24.5562
101 2X4Z X4Z 0.000003088 0.53877 24.6622
102 3M2W L8I 0.00000006711 0.51654 25.4181
103 4WHZ 3NL 0.00000000296 0.68521 25.4438
104 3TTI KBI 0.000000003846 0.64258 25.4438
105 3E7O 35F 0.0000002234 0.58133 25.4438
106 4H3P ANP 0.000001432 0.49311 25.4438
107 3PTG 932 0.00002049 0.43165 25.4438
108 1OUK 084 0.00000125 0.61485 25.7396
109 4LOO SB4 0.0000000003192 0.61423 25.7396
110 5X8I SQZ 0.00000005007 0.54052 25.7396
111 4H3Q ANP 0.0000003897 0.54021 25.7396
112 4L9I 8PR 0.000101 0.42626 25.7396
113 2JLD AG1 0.00001561 0.50839 26.0355
114 3ZRM ZRM 0.00001626 0.45851 26.0355
115 4NM5 ADP 0.00812 0.41277 26.0355
116 2PVN P63 0.0000007095 0.53303 26.1364
117 5T8O 76Z 0.000000001247 0.61347 26.3314
118 1U5R ATP 0.000001607 0.48194 26.3314
119 3F7Z 34O 0.00000208 0.49134 26.5714
120 1CM8 ANP 0.0000002944 0.50356 26.6272
121 2V7O DRN 0.0000007118 0.47117 27.0833
122 5LXC 7AA 0.00000006223 0.52001 27.2189
123 5VCV 1N1 0.00000001941 0.59704 27.3312
124 2B9H ADP 0.00000006754 0.54405 27.5148
125 2B9I ADP 0.00000004254 0.54242 27.5148
126 2B9F ADP 0.00000004292 0.54104 27.5148
127 2B9J ADP 0.00000002812 0.53856 27.5148
128 5BYZ 4WE 0.000002426 0.5375 27.5148
129 3MVH WFE 0.000008518 0.51366 27.5148
130 3GC8 B45 0.000000005756 0.60074 27.8107
131 3GC0 AMP 0.00002753 0.43262 27.8107
132 4IDT T28 0.0000000007291 0.59017 28.1065
133 4WNK 453 0.00001682 0.5018 28.1065
134 3TKI S25 0.000002055 0.5693 28.483
135 4G17 0VN 0.00003074 0.43327 28.4848
136 2HY0 306 0.0000006492 0.48151 28.5714
137 2JDR L20 0.000001151 0.58374 28.6982
138 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.000001151 0.58374 28.6982
139 4WB6 ATP 0.0000002813 0.56617 28.6982
140 3FHI ANP 0.0000003767 0.56116 28.6982
141 1RE8 BD2 0.000002469 0.5582 28.6982
142 2QCS ANP 0.0000004584 0.55779 28.6982
143 3IDB ANP 0.0000003134 0.54296 28.6982
144 2F57 23D 0.00002227 0.44386 28.7066
145 2GU8 796 0.0000000211 0.65772 28.7834
146 4U44 3D9 0.00000009596 0.53493 28.9157
147 4YZC STU 0.0000001881 0.59219 28.9941
148 4WB7 ATP 0.000005199 0.53122 28.9941
149 3V8S 0HD 0.000001606 0.48121 28.9941
150 4I6H 1C8 0.000004722 0.5574 29.2208
151 3ORK AGS 0.0001424 0.45487 29.2605
152 4UAL 3FV 0.0000002551 0.52297 29.2899
153 2RIO ADP 0.0000001094 0.52237 29.2899
154 2R5T ANP 0.000004526 0.49573 29.5858
155 4BFM ANP 0.000002607 0.49794 29.6407
156 4EUU BX7 0.000001502 0.53743 29.7806
157 5IH9 6BF 0.000009101 0.52125 29.8507
158 3TXO 07U 0.0000001345 0.50987 29.8817
159 3PVW QRX 0.0001144 0.46311 29.8817
160 5UKL SIX 0.0001748 0.45763 29.8817
161 2WEL K88 0.000002321 0.42104 29.9694
162 2VZ6 FEF 0.0000006493 0.48368 30.0319
163 4KS7 X4Z 0.00006591 0.45817 30.137
164 2F2U M77 0.0000005426 0.63349 30.1775
165 5W4W 9WG 0.00000006288 0.60143 30.1775
166 4KBA 1QM 0.00000007638 0.59103 30.1775
167 2YAB AMP 0.000008423 0.4782 30.1775
168 5UIU 8CG 0.00000004134 0.60646 30.3406
169 5HQ0 LZ9 0.00000001978 0.57024 30.4636
170 1XJD STU 0.000000005037 0.5874 30.4734
171 4YLL 4E3 0.000004136 0.50343 30.4734
172 3C0G 3AM 0.000003517 0.46067 30.4734
173 1V0O INR 0.00000002791 0.55965 30.5556
174 4OH4 ANP 0.00000005945 0.53791 30.6306
175 5LPZ ADP 0.0000002423 0.51729 30.7229
176 2BPM 529 0.000003177 0.55621 30.7443
177 3QCQ 3Q0 0.000002499 0.59153 30.7692
178 5LVP ATP 0.00003908 0.427 30.8682
179 3H9R TAK 0.0000001771 0.47147 30.9091
180 3KN5 ANP 0.000007016 0.45241 31.0769
181 1PHK ATP 0.0000001261 0.5334 31.2081
182 1VJY 460 0.00000000004214 0.73209 31.3531
183 4CFU 2WC 0.00000005457 0.52275 31.3531
184 5DBX ANP 0.000003502 0.45312 31.4024
185 4BHN BH9 0.000000006369 0.59079 31.4371
186 4BTK DTQ 0.000004259 0.4805 31.454
187 4C2W ANP 0.000009234 0.43827 31.5412
188 4BCQ TJF 0.000001578 0.46162 31.5615
189 4BCM T7Z 0.000003224 0.43491 31.5615
190 4C2V YJA 0.0000009452 0.55195 31.5789
191 3IGO ANP 0.0000001979 0.59765 31.6568
192 4OTH DRN 0.000006675 0.49133 31.6568
193 4BCN T9N 0.00000005249 0.5124 31.6667
194 4FG8 ATP 0.0000146 0.47347 31.746
195 5AX9 4KT 0.000000002259 0.58588 31.8182
196 2XMY CDK 0.0000003435 0.61457 31.8792
197 4AUA 4AU 0.000004425 0.47454 31.9218
198 3E8N ATP 0.0000001481 0.60837 31.9527
199 3E8N VRA 0.002043 0.46367 31.9527
200 5LMK 6ZK 0.0000216 0.44094 31.9865
201 5DH3 5BS 0.0000004152 0.52532 32.0635
202 2QLU ADE 0.0000002144 0.69296 32.1656
203 5EKO N17 0.000277 0.43282 32.2485
204 5JZJ AN2 0.00000006174 0.52902 32.3232
205 3SXF BK5 0.00000006413 0.60746 32.5444
206 2VN9 GVD 0.0000003006 0.46924 32.5581
207 5EYK 5U5 0.0000001203 0.58319 32.6087
208 2J7T 274 0.000002948 0.53214 32.7815
209 3UIM ANP 0.0000001137 0.52692 32.8221
210 4N70 2HX 0.0000116 0.53226 32.9268
211 4Y85 499 0.000002315 0.48409 33.1325
212 3HZT J60 0.000003028 0.45255 33.432
213 4G31 0WH 0.000002199 0.54299 33.7793
214 3DLS ADP 0.00000007915 0.5182 34.0237
215 4QMN DB8 0.00000111 0.55871 34.1936
216 4NFN 2KC 0.0000004185 0.50507 34.3042
217 2YAK OSV 0.000001761 0.54112 34.386
218 5LPB ADP 0.00000003043 0.50519 34.4595
219 4AU8 Z3R 0.0000001027 0.49192 34.4595
220 4USF 6UI 0.0000001315 0.56569 34.8684
221 3O0G 3O0 0.00000006099 0.53255 34.9315
222 1UNH IXM 0.00000007218 0.50922 34.9315
223 5DRB 5FJ 0.000007978 0.53665 35.0515
224 3OFM 4B0 0.0000002396 0.49746 35.4286
225 5TA6 79D 0.000004085 0.52241 35.4749
226 3AQV TAK 0.0001853 0.42286 35.5072
227 2XK9 XK9 0.000000003476 0.66137 35.7143
228 3CY2 MB9 0.000009791 0.49018 35.7143
229 4I94 ANP 0.000001633 0.48226 36.3333
230 4NW6 2NS 0.00000000407 0.65175 36.8421
231 5C03 AGS 0.00004238 0.44678 37.1345
232 2WEI VGG 0.00000001556 0.54014 37.2822
233 2CSN CKI 0.00001017 0.50463 37.3737
234 4WNP 3RJ 0.00000003048 0.526 37.9791
235 5G1X ADP 0.000002261 0.48366 38.2456
236 5L8L ADP 0.00001702 0.43524 38.2456
237 2WQN ADP 0.00001388 0.55618 38.3871
238 4L3L 5FI 0.0000256 0.49449 38.4868
239 5LXM ADP 0.000001116 0.49203 38.5159
240 3ALN ANP 0.0000002265 0.53189 38.5321
241 3FHR P4O 0.0000002861 0.52683 38.6905
242 5UOX 8GY 0.00000000467 0.60564 38.7454
243 2Z7R STU 0.0000002188 0.59579 38.9408
244 3PE2 E1B 0.000039 0.50749 39.4659
245 3DAK ANP 0.00001407 0.44522 40
246 5HVJ ANP 0.000005392 0.40751 40
247 4WOV 3SM 0.00001395 0.4427 40.0631
248 3GGF GVD 0.0000005378 0.49662 40.1993
249 5EW9 5VC 0.00000364 0.59329 40.2214
250 4X7Q 3YR 0.0000001928 0.52319 40.3846
251 3E5A VX6 0.00009096 0.47108 40.6716
252 5A6N U7E 0.00001479 0.4661 40.9894
253 5CEO 50D 0.000004049 0.47735 41.3333
254 4M69 ANP 0.00001007 0.47799 41.6961
255 3SLS ANP 0.0000004064 0.53227 41.7763
256 5VC5 96M 0.00000008122 0.58998 41.8685
257 5JGA 6KC 0.000000006944 0.64236 41.9048
258 2H8H H8H 0.0000000003011 0.61124 42.0118
259 1Y57 MPZ 0.00001055 0.48711 42.0118
260 5DEY 59T 0.00000129 0.578 42.0875
261 4E93 GUI 0.0000001736 0.58577 42.3077
262 5KO1 6UY 0.0000005832 0.49631 43.1095
263 5USZ SKE 0.000002386 0.53168 43.2526
264 2A19 ANP 0.00001411 0.56328 43.3099
265 3VRY B43 0.000000008534 0.61852 43.4911
266 4FL3 ANP 0.000001622 0.51196 43.787
267 4XV1 904 0.0000001056 0.59659 43.8356
268 4ITH RCM 0.000008942 0.48219 44.5578
269 5HES 032 0.000000008916 0.59348 44.6254
270 3LXN MI1 0.00000000595 0.58929 44.9686
271 4CQE CQE 0.00000001992 0.58333 46.0432
272 3KMW ATP 0.00001044 0.45694 46.1255
273 4Y93 746 0.00001107 0.49757 46.4497
274 1K3A ACP 0.000001959 0.46382 46.8227
275 4GJ3 0XP 0.000000002286 0.65943 47.351
276 1OPK P16 0.0000006354 0.56095 47.6331
277 3LXK MI1 0.00000001482 0.61931 47.7064
278 4YZN 4K5 0.0000003667 0.54396 48.7805
279 4E1Z 0MX 0.0000003511 0.54228 49.1409
280 5HX8 66P 0.0000002494 0.56824 49.6689
281 3G5D 1N1 0.00000001701 0.66177 50
Pocket No.: 2; Query (leader) PDB : 3PP0; Ligand: 03Q; Similar sites found: 33
This union binding pocket(no: 2) in the query (biounit: 3pp0.bio2) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3AKK ADP 0.001757 0.40977 1.53846
2 1AUX AGS 0.0003479 0.42749 1.60772
3 1EHI ADP 0.001885 0.4065 1.77515
4 5VZ0 ADP 0.00122 0.40529 1.77515
5 2ZHL NAG GAL GAL NAG 0.005917 0.42393 2.7027
6 1IOW PHY 0.01067 0.40211 2.94118
7 1IOW ADP 0.01067 0.40211 2.94118
8 3ITJ FAD 0.01367 0.4107 2.95858
9 4NZN ANP 0.008467 0.41483 3.0303
10 4NZN 2OU 0.008467 0.41483 3.0303
11 5TDF ADP 0.003167 0.40182 3.7037
12 3I0O ADP 0.0001936 0.41275 4.43787
13 2BKK ADP 0.000129 0.43021 4.54545
14 2IO8 ADP 0.004231 0.40677 4.73373
15 3HAV ATP 0.003523 0.41328 5.01672
16 4OCV ANP 0.0004977 0.43045 5.02959
17 2VPQ ANP 0.004613 0.40354 5.02959
18 3VOT ADP 0.0006158 0.40047 5.6213
19 3PDT ADP 0.001005 0.41014 6.54545
20 2WET FAD 0.01271 0.40697 6.80473
21 4O4F IHP 0.006923 0.401 6.85484
22 4O4F ATP 0.006368 0.401 6.85484
23 4C5N PXL 0.003762 0.42169 7.24638
24 1JL0 PUT 0.009066 0.41467 7.48503
25 5W2I I3P 0.001967 0.42054 7.7821
26 5W2I ADP 0.001967 0.42054 7.7821
27 5C4L 4XR 0.002848 0.423 12.1495
28 2GJ5 VD3 0.01294 0.40174 12.3457
29 2IF8 ADP 0.0001994 0.40499 12.7219
30 4PU5 ANP 0.00367 0.40763 13.0178
31 4XYM A12 0.00252 0.4023 14.3478
32 2PZI AXX 0.0004758 0.41437 24.2604
33 1O9U ADZ 0.0000001753 0.40403 27.8107
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