Receptor
PDB id Resolution Class Description Source Keywords
3PQC 1.9 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF THERMOTOGA MARITIMA RIBOSOME BIOGENESIS BINDING PROTEIN ENGB (YSXC/YIHA) IN COMPLEX WITH GDP THERMOTOGA MARITIMA ROSSMANN FOLD GTPASE GTP BINDING CELL CYCLE HYDROLASE
Ref.: STRUCTURE OF AN ESSENTIAL GTPASE, YSXC, FROM THERMO MARITIMA ACTA CRYSTALLOGR.,SECT.F V. 67 640 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP A:801;
B:802;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
PEG A:196;
B:196;
Invalid;
Invalid;
none;
none;
submit data
106.12 C4 H10 O3 C(COC...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3PQC 1.9 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF THERMOTOGA MARITIMA RIBOSOME BIOGENESIS BINDING PROTEIN ENGB (YSXC/YIHA) IN COMPLEX WITH GDP THERMOTOGA MARITIMA ROSSMANN FOLD GTPASE GTP BINDING CELL CYCLE HYDROLASE
Ref.: STRUCTURE OF AN ESSENTIAL GTPASE, YSXC, FROM THERMO MARITIMA ACTA CRYSTALLOGR.,SECT.F V. 67 640 2011
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 473 families.
1 3PQC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 355 families.
1 3PQC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 143 families.
1 1SVI - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 3PQC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3PQC; Ligand: GDP; Similar sites found: 549
This union binding pocket(no: 1) in the query (biounit: 3pqc.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3RAB GNP 0.000000005978 0.70566 None
2 1Z0K GTP 0.000000009269 0.69076 None
3 2BME GNP 0.00000001863 0.6824 None
4 1X1R GDP 0.00000002279 0.68098 None
5 1G16 GDP 0.00000009166 0.64142 None
6 3Q72 GNP 0.000000005693 0.63498 None
7 3X1Z GNP 0.00000006733 0.50468 None
8 3TMK T5A 0.0004358 0.48164 None
9 2IL4 COA 0.00913 0.40178 None
10 1BO4 COA 0.004521 0.40002 None
11 4WOP CTP 0.0001838 0.43883 1.33333
12 3QBT GNP 0.00000001387 0.54381 1.42857
13 2QG6 NMN 0.00029 0.4884 1.53846
14 3P4X ADP 0.00003639 0.48045 1.53846
15 1JJ7 ADP 0.000003011 0.46082 1.53846
16 2ZE7 DST 0.005388 0.42652 1.53846
17 2ZE7 AMP 0.005667 0.42394 1.53846
18 1OW3 GDP 0.00000001647 0.6659 1.5544
19 2ZEJ GDP 0.0000009358 0.60459 1.63043
20 1TX4 ALF GDP 0.00000004832 0.54776 1.69492
21 1KAO GDP 0.0000000363 0.65024 1.79641
22 4AG5 ADP 0.00002293 0.55283 2.05128
23 1M7G ADX 0.0001543 0.50648 2.05128
24 1M7G AV2 0.000006775 0.50648 2.05128
25 1M7G ADP 0.000151 0.50361 2.05128
26 2CHG ANP 0.0001895 0.48065 2.05128
27 3DC4 ADP 0.00003497 0.46548 2.05128
28 1Z6T ADP 0.0001317 0.4599 2.05128
29 1T8U UAP SGN IDS SGN 0.01334 0.42194 2.05128
30 1T8U A3P 0.004846 0.4203 2.05128
31 3MGB PAP 0.009961 0.40581 2.05128
32 2R75 01G 0.019 0.40315 2.05128
33 1ZUI SKM 0.001283 0.46757 2.38095
34 5MVR ADP 0.00003863 0.48682 2.46914
35 2XTZ GSP 0.000001301 0.59549 2.5641
36 1DAR GDP 0.0000003336 0.58021 2.5641
37 4ZNL BEF ADP 0.0000595 0.50445 2.5641
38 5GVR LMR 0.0003705 0.49558 2.5641
39 1T5C ADP 0.0000008171 0.47992 2.5641
40 3DZD ADP 0.0004127 0.46281 2.5641
41 1VHT BA3 0.0008572 0.44597 2.5641
42 4GBM A3P 0.002698 0.43576 2.5641
43 5WRJ A3P 0.004256 0.4282 2.5641
44 2A5J GDP 0.00000001093 0.66627 2.6178
45 1Z0A GDP 0.00000001523 0.65979 2.87356
46 4HDO GNP 0.00000004938 0.66508 3.07692
47 2F9L GDP 0.0000001573 0.63338 3.07692
48 1JI0 ATP 0.00003441 0.53781 3.07692
49 4R43 GDP 0.00002898 0.52594 3.07692
50 5LB3 ADP 0.00004316 0.52508 3.07692
51 4HSE ADP 0.00002656 0.50375 3.07692
52 1P72 ADP 0.0003698 0.48971 3.07692
53 5IRN ADP 0.0001097 0.48889 3.07692
54 4PX9 ADP 0.0002751 0.48603 3.07692
55 1IN4 ADP 0.0002666 0.47624 3.07692
56 3FB4 AP5 0.001608 0.46752 3.07692
57 4P32 ADP 0.000877 0.45663 3.07692
58 4OHY ANP 0.0001433 0.41666 3.07692
59 1HTW ADP 0.00007941 0.48348 3.16456
60 1KO8 6PG 0.0004545 0.46561 3.42857
61 1GWN GTP 0.00000001529 0.67429 3.58974
62 5CK5 GDP 0.000000006585 0.63397 3.58974
63 3UIE ANP 0.00001503 0.52502 3.58974
64 3ZS9 ADP ALF 0.0001014 0.50826 3.58974
65 1X6V ADP 0.000159 0.50255 3.58974
66 2OFW ADX 0.0003014 0.50225 3.58974
67 3BFV ADP 0.000112 0.49817 3.58974
68 3ZFD ANP 0.00008946 0.49015 3.58974
69 1G6O ADP 0.0001002 0.48793 3.58974
70 2C9O ADP 0.0003781 0.47149 3.58974
71 5G41 AP5 0.001817 0.47013 3.58974
72 2QZ4 ADP 0.0002739 0.46828 3.58974
73 4IDN GNP 0.00002082 0.46411 3.58974
74 4XTR ADP 0.00006543 0.46406 3.58974
75 2OZE AGS 0.0005365 0.46231 3.58974
76 3FYH ADP 0.001063 0.45649 3.58974
77 3EWA ANP 0.0002473 0.45257 3.58974
78 1ION ADP 0.0006399 0.45169 3.58974
79 1G3Q ADP 0.0004269 0.45138 3.58974
80 4XGU ADP 0.0003563 0.44525 3.58974
81 2C04 GCP 0.0004322 0.44307 3.58974
82 2D7D ADP 0.0008802 0.43489 3.58974
83 4XTR ATP 0.00009204 0.43323 3.58974
84 4XVU ATP 0.000113 0.43026 3.58974
85 1OE0 TTP 0.006278 0.42336 3.58974
86 4KBF AMP 0.001374 0.41784 3.58974
87 2WOJ ADP ALF 0.0001055 0.41099 3.58974
88 4A4Z ANP 0.004081 0.40411 3.58974
89 2J5V PCA 0.03865 0.40238 3.58974
90 3LXR GDP 0.000000005131 0.68105 3.64583
91 4XOI GTP 0.00000004316 0.66245 3.7037
92 1M7B GTP 0.00000001004 0.60072 3.80435
93 2PEZ DAT 0.0001873 0.50399 3.91061
94 1H65 GDP 0.00000007688 0.64497 4.10256
95 3VMF GTP 0.0000001498 0.63973 4.10256
96 1D2E GDP 0.00000005368 0.63892 4.10256
97 4LPS GDP 0.0000001746 0.60104 4.10256
98 2NCD ADP 0.000008512 0.5745 4.10256
99 1SVK ALF GDP 0.000008452 0.56534 4.10256
100 1BH2 GSP 0.00001382 0.55321 4.10256
101 1RJ9 GCP 0.00009038 0.53315 4.10256
102 3FWY ADP 0.00002823 0.51837 4.10256
103 2IYL GDP 0.00001663 0.50666 4.10256
104 3BOS CDP 0.00004659 0.48242 4.10256
105 2BIF SIN 0.001037 0.48026 4.10256
106 2BIF ANP 0.0006207 0.48026 4.10256
107 5M7P ADP 0.0002607 0.47669 4.10256
108 4TTQ ATP 0.0001295 0.46637 4.10256
109 5X40 ACP 0.0009085 0.45784 4.10256
110 2FNA ADP 0.00005778 0.44878 4.10256
111 2GDJ ANP 0.0004336 0.44308 4.10256
112 2ZTS ADP 0.0003334 0.43396 4.10256
113 5E5U MLI 0.01232 0.42833 4.10256
114 2JAQ DCP 0.006858 0.41681 4.10256
115 2VBQ BSJ 0.02661 0.40299 4.24242
116 1GXU 2HP 0.00009287 0.52694 4.3956
117 4H1V GNP 0.000007772 0.51406 4.60705
118 4J0Q GDP 0.00000002035 0.68653 4.61538
119 1SKQ GDP 0.0000001319 0.58168 4.61538
120 5L3V GDP 0.00001349 0.52713 4.61538
121 1IHU ADP 0.00006406 0.51159 4.61538
122 1DAK DPU 0.000233 0.51145 4.61538
123 1IHU AF3 0.00006111 0.51034 4.61538
124 5GJC ATP 0.0002513 0.48158 4.61538
125 5LTJ ADP 0.0002368 0.46224 4.61538
126 2IS6 ADP 0.000145 0.46221 4.61538
127 1W5T ANP 0.0009506 0.453 4.61538
128 2XAU ADP 0.0007511 0.44855 4.61538
129 2JLR ANP 0.0008976 0.44752 4.61538
130 2WHX ADP 0.00004818 0.44702 4.61538
131 3DKP ADP 0.0003797 0.44677 4.61538
132 1W5T ADP 0.001753 0.43656 4.61538
133 1NST A3P 0.002096 0.43302 4.61538
134 4YLG GDP 0.0000001524 0.58399 4.62428
135 3KTA AP5 0.0003956 0.46365 4.62428
136 1Z0J GTP 0.00000002572 0.67849 4.70588
137 1YVD GNP 0.00000001116 0.69289 4.73373
138 4WZ6 ATP 0.00001543 0.5624 5.12821
139 4LYA ATP 0.00003023 0.51802 5.12821
140 2PZE ATP 0.000003958 0.47221 5.12821
141 1G41 ADP 0.0002286 0.47181 5.12821
142 1S3G AP5 0.001354 0.47121 5.12821
143 1OFH ADP 0.0002864 0.4674 5.12821
144 2VF7 ADP 0.0003609 0.45499 5.12821
145 4TMK T5A 0.006095 0.43209 5.12821
146 1OYY AGS 0.002909 0.4104 5.12821
147 4JLV ADP 0.00221 0.40782 5.12821
148 5MEX SZZ 0.02928 0.40297 5.12821
149 5MEX PAP 0.0109 0.40219 5.12821
150 3IIJ ADP 0.00002734 0.49283 5.55556
151 4D0N GDP 0.000000002905 0.6613 5.64103
152 3ZQ6 ADP ALF 0.0001487 0.50038 5.64103
153 1QF5 GDP 0.0006509 0.49651 5.64103
154 2XT3 ADP 0.000002432 0.48434 5.64103
155 4PFO ADP 0.0003591 0.48046 5.64103
156 2Q2Y MKR 0.001206 0.47254 5.64103
157 2Q2Y ADP 0.001333 0.47155 5.64103
158 2W58 ADP 0.000003197 0.46305 5.64103
159 4FCW ADP 0.0004107 0.45369 5.64103
160 2OBM ADP 0.00002944 0.44522 5.64103
161 4IEE AGS 0.00343 0.43282 5.64103
162 4LJ9 ACP 0.001049 0.42922 5.64103
163 2ZPT A3P 0.02118 0.42266 5.64103
164 2Z5F A3P 0.004351 0.42247 5.64103
165 4QRH 0O2 0.006241 0.41522 5.64103
166 1AQU A3P 0.00745 0.40785 5.64103
167 1ZC3 GNP 0.00000002723 0.67732 5.71429
168 1UAD GNP 0.00000003513 0.66941 5.71429
169 1Z06 GNP 0.000000005223 0.70547 5.82011
170 1TU3 GNP 0.000000006822 0.70296 5.84795
171 1R2Q GNP 0.00000003506 0.6884 5.88235
172 3MJH GTP 0.00000000766 0.55342 5.95238
173 1U8Z GDP 0.00000006386 0.54687 5.95238
174 4KVG GTP 0.00000002067 0.68027 6.15385
175 1UJ2 C5P 0.000261 0.48881 6.15385
176 1UJ2 ADP 0.00029 0.48665 6.15385
177 3FVQ ATP 0.0001872 0.48558 6.15385
178 5FTB ANP 0.0001413 0.48122 6.15385
179 2CE7 ADP 0.0002082 0.47364 6.15385
180 1GP2 GDP 0.00003164 0.46154 6.15385
181 3VX3 ADP 0.0005921 0.46034 6.15385
182 5FHD ADP ALF 0.0001817 0.43649 6.15385
183 2GWH A3P 0.003927 0.42057 6.15385
184 1VKJ A3P 0.00577 0.41679 6.15385
185 1QF9 C5P 0.003139 0.44976 6.18557
186 4LHW GNP 0.000000006061 0.55455 6.32184
187 4RD0 GDP 0.00000008906 0.642 6.66667
188 5TSH ANP 0.00003184 0.48963 6.66667
189 3QXC ATP 0.0002566 0.48917 6.66667
190 1R0X ATP 0.00007026 0.46695 6.66667
191 5TSH ADP 0.00002713 0.46236 6.66667
192 2PL3 ADP 0.0001074 0.46054 6.66667
193 4V03 ADP 0.0004281 0.45955 6.66667
194 3B5J 12D 0.0000608 0.45881 6.66667
195 4D81 ADP 0.000272 0.45773 6.66667
196 1OS1 ATP 0.001604 0.4546 6.66667
197 1OS1 PYR 0.001722 0.4546 6.66667
198 1XKV ATP 0.0005832 0.4535 6.66667
199 1UKZ ADP 0.002332 0.45237 6.66667
200 3QKT ANP 0.00165 0.44752 6.66667
201 1L2T ATP 0.0002942 0.40607 6.66667
202 3IUY AMP 0.005471 0.40025 6.66667
203 4MKG AP5 0.001625 0.46729 6.91244
204 2QQ0 ANP 0.00004962 0.53187 7.06522
205 2QQ0 TMP 0.00004993 0.53174 7.06522
206 2QQ0 THM 0.0001362 0.50746 7.06522
207 2G77 GDP 0.000000006993 0.63786 7.17949
208 4ZKD GDP 0.0000004972 0.6176 7.17949
209 2B8W ALF 5GP 0.00002977 0.52932 7.17949
210 1IWE IMP 0.0007157 0.52271 7.17949
211 3IO3 ADP 0.00007056 0.50275 7.17949
212 3RLF ANP 0.000157 0.49342 7.17949
213 2ZPA ADP 0.0002269 0.47946 7.17949
214 2ZR9 DTP 0.00009277 0.47066 7.17949
215 2AWN ADP 0.000000478 0.46944 7.17949
216 1F5N GNP 0.000001991 0.46635 7.17949
217 1JJV ATP 0.00003458 0.45681 7.17949
218 4RZ3 ADP 0.000787 0.45244 7.17949
219 5VGR GDP 0.0002433 0.44998 7.17949
220 1FNN ADP 0.0002737 0.44128 7.17949
221 1YTM ATP 0.0001837 0.44073 7.17949
222 2G77 AF3 0.003963 0.44008 7.17949
223 1G3M PCQ 0.01809 0.41437 7.17949
224 2ORV 4TA 0.009063 0.4143 7.17949
225 4ZG4 VO4 ADP 0.0003043 0.41157 7.17949
226 2B8T THM 0.009265 0.40902 7.17949
227 5MW4 5JU 0.03068 0.40569 7.17949
228 3FS1 MYR 0.008196 0.40391 7.17949
229 1WG8 SAM 0.01525 0.40358 7.17949
230 3QWI NAP 0.02897 0.4001 7.17949
231 1XX6 ADP 0.00005147 0.48036 7.32984
232 1XTQ GDP 0.00000002356 0.67186 7.34463
233 1UPT GTP 0.000001238 0.58895 7.60234
234 3AQ4 GDP 0.0000003466 0.58809 7.6087
235 4QM7 GTP 0.00003502 0.4885 7.69231
236 1V8K ANP 0.00004573 0.48368 7.69231
237 1K6M AGS 0.0002755 0.48203 7.69231
238 3FKQ ATP 0.0001246 0.46348 7.69231
239 2RGX AP5 0.002282 0.46214 7.69231
240 5IFS ADP 0.0004158 0.46012 7.69231
241 4U00 ADP 0.000003798 0.45985 7.69231
242 3Q9L ATP 0.0005664 0.45896 7.69231
243 5XDR ADP 0.0007075 0.45486 7.69231
244 1G6H ADP 0.000006811 0.45126 7.69231
245 3TBK ANP 0.000208 0.44616 7.69231
246 2O0J ADP 0.001974 0.40369 7.69231
247 3E5H GNP 0.0000004889 0.61552 7.86517
248 5H67 ATP 0.00906 0.40371 7.97872
249 1D5C GDP 0.00000001009 0.67561 8.02469
250 1MH1 GNP 0.00000001284 0.53484 8.06452
251 1CXZ GSP 0.00000004627 0.6552 8.13953
252 2FFQ GSP 0.00000006376 0.65982 8.18713
253 1VG8 GNP 0.0000000338 0.67287 8.20513
254 1VG0 GDP 0.00000001113 0.66988 8.20513
255 5HPY GDP 0.00000002563 0.65713 8.20513
256 3WXM GTP 0.0000002062 0.63319 8.20513
257 2FAH GDP 0.00005056 0.50414 8.20513
258 3COB ADP 0.000002668 0.48389 8.20513
259 5I0H ADP BEF 0.0002355 0.48098 8.20513
260 1NY5 ADP 0.0002169 0.47798 8.20513
261 1R6B ADP 0.0001464 0.47278 8.20513
262 3KJI ADP 0.0003508 0.46601 8.20513
263 3DOE GTP 0.0000001265 0.63779 8.33333
264 3H86 AP5 0.006246 0.43278 8.33333
265 2A5F GTP 0.000004423 0.56816 8.57143
266 1KSH GDP 0.00000001758 0.6715 8.60215
267 2QN6 GDP 0.000000007453 0.63113 8.60215
268 1GUA GNP 0.00000006049 0.51647 8.64198
269 3GJ0 GDP 0.000000005077 0.70357 8.71795
270 3GJ8 GDP 0.00000001856 0.66613 8.71795
271 1IBR GNP 0.00000009347 0.65196 8.71795
272 5UWI GNP 0.00000009714 0.65117 8.71795
273 3GJ4 GDP 0.000000005071 0.64986 8.71795
274 5UWP GNP 0.0000001219 0.64896 8.71795
275 4HAT GNP 0.0000001365 0.64661 8.71795
276 3GJ7 GDP 0.000000006384 0.64573 8.71795
277 5UWT GNP 0.0000001283 0.64545 8.71795
278 1GOJ ADP 0.000000711 0.64375 8.71795
279 5BXQ GDP 0.00000001705 0.64326 8.71795
280 3GJ3 GDP 0.000000008259 0.64106 8.71795
281 3GJ5 GDP 0.000000019 0.64103 8.71795
282 3CH5 GDP 0.00000002471 0.63617 8.71795
283 1TAD GDP 0.000006353 0.56933 8.71795
284 1ZCB GDP 0.00001101 0.55179 8.71795
285 1FQK GDP 0.00001804 0.53728 8.71795
286 4YMU ATP 0.0000829 0.51132 8.71795
287 5UWU GNP 0.0000001011 0.50976 8.71795
288 5DIF GNP 0.0000001012 0.50956 8.71795
289 5UWR GNP 0.0000001087 0.5093 8.71795
290 5UWO GNP 0.0000001113 0.50906 8.71795
291 5UWQ GNP 0.0000001074 0.509 8.71795
292 5UWJ GNP 0.0000001122 0.50894 8.71795
293 5UWH GNP 0.0000001112 0.50877 8.71795
294 5UWW GNP 0.0000001175 0.5081 8.71795
295 5DHF GNP 0.000000122 0.50798 8.71795
296 5DI9 GNP 0.0000001489 0.49687 8.71795
297 5UWS GNP 0.0000001754 0.49568 8.71795
298 4HI0 GDP 0.00001589 0.48833 8.71795
299 1FQJ GDP 0.00000465 0.48777 8.71795
300 5N69 ADP 0.0001883 0.46428 8.71795
301 4IHQ ADP 0.00008168 0.46366 8.71795
302 4R2I ANP 0.001161 0.46159 8.71795
303 1TAD ALF 0.000006353 0.44714 8.71795
304 1U0J ADP 0.0008505 0.42393 8.71795
305 1FQJ ALF 0.01823 0.40511 8.71795
306 5EE5 GTP 0.0000001817 0.62763 8.77193
307 1YZQ GNP 0.00000003943 0.6697 8.82353
308 1MR3 G3D 0.0000002505 0.59385 8.83978
309 4KAX GTP 0.00000093 0.59471 8.87574
310 1R4A GNP 0.0000003047 0.62264 9.09091
311 1VG1 GDP 0.000000007817 0.65855 9.18919
312 1VG9 GDP 0.000000008851 0.65629 9.18919
313 1LFD GNP 0.00000004555 0.6641 9.1954
314 3TNF GNP 0.00000001456 0.69284 9.23077
315 2CBZ ATP 0.0000005209 0.65821 9.23077
316 5IRC GDP 0.00000004129 0.64029 9.23077
317 5GOE GDP 0.0000001377 0.61674 9.23077
318 4PPF FLC 0.000004205 0.59605 9.23077
319 4WEI GLC GAL 0.003973 0.43861 9.23077
320 4IOK ADP 0.005181 0.42881 9.23077
321 4IOK XPO 0.00659 0.41927 9.23077
322 1Q20 PLO 0.01561 0.41219 9.23077
323 3N5C GDP 0.0000002054 0.62758 9.25926
324 3PCR GTP 0.0000007091 0.51379 9.25926
325 3TK1 GDP 0.000000004325 0.61904 9.74359
326 3MD0 GDP 0.00000005627 0.59456 9.74359
327 3E70 GDP 0.00001652 0.51511 9.74359
328 2KIN ADP 0.0000002252 0.49752 9.74359
329 5I34 GDP 0.0001433 0.47474 9.74359
330 1Y63 ADP 0.00004155 0.48472 9.78261
331 5WDR GNP 0.00000005923 0.66134 9.94152
332 2X77 GDP 0.00000000113 0.69455 10.0529
333 4DKX GDP 0.00000000495 0.70409 10.2564
334 5JCP GDP ALF 0.00000005749 0.59999 10.2564
335 5L3W GDP 0.00001044 0.53214 10.2564
336 5H56 ADP 0.0005494 0.4784 10.2564
337 5H56 TYD 0.0005494 0.4784 10.2564
338 3B7G ANP 0.0001693 0.47 10.2564
339 5L3S GNP 0.00003284 0.44637 10.2564
340 2BEK ATP 0.0005056 0.4163 10.2564
341 5L3S G 0.01592 0.40924 10.2564
342 5K5Z ANP 0.0004415 0.40456 10.2564
343 3REF GDP 0.000000006714 0.69412 10.3093
344 4V0K GDP 0.000001286 0.49478 10.6509
345 4LC1 GDP 0.000000004896 0.70431 10.7692
346 3CPJ GDP 0.000000002687 0.69786 10.7692
347 3M1I GTP 0.00000009991 0.65059 10.7692
348 2EFE GNH 0.00000004253 0.6435 10.7692
349 3WYF GTP 0.0000002357 0.63534 10.7692
350 2BCG GDP 0.00000001265 0.61078 10.7692
351 5HR5 ADP 0.0001838 0.48126 10.7692
352 3EZ2 ADP 0.000565 0.47086 10.7692
353 1SVM ATP 0.00214 0.46848 10.7692
354 1RRC ADP 0.000009404 0.46009 10.7692
355 5KUT GDP 0.000000004607 0.66791 11.1111
356 2Y8E GNP 0.00000005456 0.52925 11.1732
357 2QEN ADP 0.00001419 0.532 11.2821
358 3B9Q MLI 0.00006793 0.53163 11.2821
359 1CR1 TTP 0.00009123 0.49999 11.2821
360 5L3R GCP 0.00004008 0.44306 11.2821
361 2F3R G5P 0.01739 0.40873 11.2821
362 2GK6 ADP 0.002205 0.4013 11.2821
363 1WA5 GTP 0.0000001201 0.47496 11.3636
364 3WYG GTP 0.0000009785 0.60594 11.5385
365 1SQ5 ADP 0.00002741 0.50247 11.7949
366 1BG2 ADP 0.0000002644 0.49559 11.7949
367 1NJF ADP 0.0002094 0.48106 11.7949
368 1NJF AGS 0.0003312 0.47627 11.7949
369 5MZN ADP 0.0007011 0.47252 11.7949
370 1YQT ADP 0.000061 0.44823 11.7949
371 1S8F GDP 0.00000007207 0.65981 11.8644
372 3BER AMP 0.005364 0.41867 12.0482
373 2DPY ADP 0.00004708 0.53102 12.3077
374 3ZIA ADP 0.00001531 0.52766 12.3077
375 3ZIA ATP 0.00001448 0.51535 12.3077
376 4BQS ADP 0.00004771 0.5157 12.5
377 5UQW GDP 0.00000001532 0.68355 12.6984
378 2VB6 ADP BEF 0.0003211 0.47893 12.7517
379 1ZD9 GDP 0.0000000262 0.60169 12.766
380 1TQ4 GDP 0.000000003182 0.62227 12.8205
381 2XTN GTP 0.0000003704 0.61603 12.8205
382 4XSH GSP 0.00000001973 0.60274 12.8205
383 1AZT GSP 0.000006385 0.56923 12.8205
384 1G7C 5GP 0.000005887 0.52667 12.8205
385 1LVG ADP 0.000006796 0.49309 12.8205
386 1NN5 ANP 0.0003642 0.48853 12.8205
387 2IXE ATP 0.0003704 0.47401 12.8205
388 4E03 ADP 0.0003284 0.45728 12.8205
389 2FSH ANP 0.0009697 0.42491 12.8205
390 5TB5 GDP 0.00000001431 0.66101 12.973
391 5TAR GDP 0.00000001655 0.6387 12.973
392 3A4M ADP 0.000007362 0.49062 13.0769
393 4DSU GDP 0.00000003716 0.67092 13.2275
394 1RYH GNP 0.000000004983 0.68162 13.3333
395 3EC1 GDP 0.00000001441 0.64658 13.3333
396 1F2U ATP 0.002148 0.44546 13.4228
397 2NGR GDP 0.00000000229 0.68109 13.6126
398 4ITR GDP 0.000000009765 0.67985 13.6126
399 1GRN GDP 0.000000009805 0.67617 13.6126
400 1A4R GDP 0.00000001181 0.67606 13.6126
401 1A4R GNH 0.00000001178 0.67254 13.6126
402 4YDS ATP 0.00008386 0.51852 13.8462
403 1WDT GTP 0.00004777 0.47029 13.8462
404 4QOS ADP 0.000487 0.45703 13.8462
405 3DDC GNP 0.00000002474 0.67929 13.8554
406 2C5L GTP 0.00000002203 0.68167 13.8728
407 5XCO GDP 0.000000004582 0.68736 14.0351
408 1G4U GDP 0.000000005942 0.68975 14.1304
409 5O2T GSP 0.00000001927 0.52964 14.2012
410 5E95 GDP 0.00000001389 0.62385 14.2857
411 1G7S GDP 0.000000025 0.66016 14.359
412 1PUJ GNP 0.00000007942 0.63121 14.359
413 2HF9 GSP 0.000003017 0.53238 14.359
414 1W7J ADP BEF 0.0002139 0.45188 14.359
415 1NVV GNP 0.00000002223 0.68148 14.4578
416 1NVU GTP 0.00000003569 0.67175 14.4578
417 2UZI GTP 0.00000003364 0.6703 14.4578
418 3KUD GDP 0.00000002132 0.66763 14.4578
419 1WQ1 GDP 0.00000004148 0.6604 14.4578
420 5UFQ GNP 0.00000002997 0.53401 14.4578
421 1CLU DBG 0.0000001319 0.41375 14.4578
422 4OI4 ATP 0.0002929 0.48078 14.7826
423 4K81 GTP 0.00000002159 0.6847 14.8718
424 2WMO GTP 0.00000001419 0.66117 14.8718
425 1F9V ADP 0.000006334 0.48577 14.8718
426 1ZIN AP5 0.001227 0.47333 14.8718
427 4HDQ GNP 0.00000005353 0.66342 15.3846
428 4R98 GNH 0.000001156 0.5921 15.3846
429 2ZFI ADP 0.00003765 0.52056 15.3846
430 1CS4 GSP 0.00001164 0.44827 15.3846
431 4YS0 ADP 0.0006567 0.4347 15.3846
432 2W83 GTP 0.000001267 0.5911 15.5844
433 1B0U ATP 0.0003783 0.46453 15.6489
434 2RCN GDP 0.000000002881 0.66338 15.8974
435 3GJX GTP 0.00000009965 0.65064 15.8974
436 3CNL GNP 0.00000008442 0.59058 15.8974
437 1B7T ADP 0.0002983 0.46661 16.0256
438 1KK8 BEF ADP 0.0002171 0.47796 16.2338
439 2HV8 GTP 0.00000001896 0.68204 16.2791
440 4MKF AP5 0.001193 0.47506 16.4103
441 5J1J ANP 0.0001689 0.42393 16.4103
442 3BFX A3P 0.001245 0.41658 16.4103
443 3WY9 GDP 0.000000005212 0.63646 16.5899
444 3WYA GDP 0.00000002301 0.62548 16.5899
445 1DS6 GDP 0.0000000004574 0.69397 16.6667
446 4DID GDP 0.000000004855 0.66767 16.9231
447 5IRR GSP 0.000001827 0.50569 16.9231
448 1OXV ANP 0.00003497 0.47603 16.9231
449 3SBD GNP 0.000000008632 0.55211 17.1123
450 1OIV GDP 0.00000001853 0.6825 17.2775
451 2W2X GSP 0.000000009433 0.68398 17.2973
452 2HCJ GDP 0.000000001943 0.65192 17.4359
453 1NF3 GNP 0.00000002575 0.53601 17.4359
454 4GOX A3P 0.0008266 0.45975 17.4359
455 5JCZ GDP 0.00000004727 0.58878 17.8771
456 4LX0 BEF GDP 0.00000004039 0.66921 18.0791
457 4YC7 GNP 0.00000001303 0.68075 18.232
458 1FP6 ADP 0.00009836 0.49104 18.4615
459 4C4P GNP 0.00000002835 0.67649 18.4971
460 4NCN GTP 0.00000003765 0.66236 18.9744
461 4TMZ GSP 0.00000005019 0.65653 18.9744
462 4CVN ADP 0.00000272 0.59277 19.3717
463 3DEF GDP 0.000000005706 0.68304 19.4872
464 2V7Q ATP 0.00000785 0.53772 19.4872
465 1W0J ADP 0.00001287 0.53108 19.4872
466 1P9B GDP 0.0001306 0.48803 19.4872
467 4KFU ACP 0.000005905 0.48763 19.4872
468 2V7Q ADP 0.0001888 0.46021 19.4872
469 1W0J ADP BEF 0.0005984 0.46013 19.4872
470 1D2N ANP 0.001432 0.44478 19.4872
471 2CK3 ANP 0.0007094 0.42437 19.4872
472 2CK3 ADP 0.0004387 0.41232 19.4872
473 3LRE ADP 0.000002321 0.46887 20
474 1NRJ GTP 0.00000143 0.58331 20.5128
475 1GOT GDP 0.00002205 0.53088 21.0256
476 3T34 GDP 0.000008012 0.4821 21.0256
477 1Z08 GNP 0.0000001081 0.64099 21.1765
478 1I4D GDP 0.0000000002789 0.68463 22.3958
479 2VVG ADP 0.000000766 0.484 22.5641
480 5FG3 GDP 0.000000001104 0.66209 23.0769
481 5HCN GCP 0.000000007242 0.68497 23.5897
482 2C78 GNP 0.0000001349 0.63363 23.5897
483 2C77 GNP 0.0000005379 0.60291 23.5897
484 2WKQ GTP 0.000000005766 0.57948 23.5897
485 1E96 GTP 0.000000009498 0.69618 23.9583
486 2FJU GSP 0.00000000653 0.69135 24.1573
487 1HE1 GDP 0.00000000681 0.60448 24.4318
488 1HE1 AF3 0.02316 0.40074 24.4318
489 4WZA ACP 0.000598 0.50633 24.6154
490 4WZA ADP 0.000598 0.50633 24.6154
491 2OM2 GDP 0.00001712 0.48521 25
492 5SZH GNP 0.00000001378 0.69133 25.1282
493 3TKL GTP 0.00000001434 0.6849 25.1282
494 1JWY GDP 0.00001151 0.53327 25.641
495 2Y65 ADP 0.00000111 0.49332 25.641
496 1JWY ADP 0.00009963 0.47863 25.641
497 3U6B GDP 0.000000002329 0.73222 26.1538
498 5JBQ GDP 0.000000007335 0.69601 26.1538
499 4G5G GDP 0.000000007565 0.64443 26.1538
500 1D8T GDP 0.000000008454 0.64245 26.1538
501 4P3Y GDP 0.000000004223 0.6398 26.1538
502 3U6K GDP 0.00000001099 0.63863 26.1538
503 2BVN GNP 0.00000004562 0.62056 26.1538
504 4PC3 GDP 0.00000005214 0.61923 26.1538
505 3SFV GDP 0.00000001115 0.68063 27.0718
506 3NKV GNP 0.00000000587 0.70603 28
507 4M9Q GNP 0.0000001562 0.54731 28.2051
508 3T1O GDP 0.000007505 0.53859 28.2051
509 3T12 GDP ALF 0.00001096 0.48328 28.2051
510 1KK1 GNP 0.00000008092 0.59237 28.7179
511 1Z2A GDP 0.00000002425 0.56786 29.1667
512 5KSZ GCP 0.00000003907 0.64137 29.2308
513 5KSP GDP 0.00000001939 0.66525 30
514 1M2O GNP 0.0000001118 0.64572 30.5263
515 2FH5 GTP 0.00000001559 0.67391 30.7692
516 2A9K GDP 0.00000001899 0.66307 31.016
517 1F6B GDP 0.0000002521 0.59515 32.8205
518 1WF3 GNP 0.0000000004331 0.76246 33.8462
519 1OIX GDP 0.00000007168 0.65482 34.359
520 2QTV GNP 0.000000214 0.62984 34.7305
521 2WIC GNP 0.000001021 0.58587 34.8718
522 4BAS GNP 0.000004117 0.56472 35.3846
523 1Z0F GDP 0.000000004341 0.66854 35.7542
524 4D0G GTP 0.00000002465 0.6679 36
525 4NON GDP 0.00000004941 0.50935 36.4103
526 5DI3 GNP 0.0000002072 0.54374 37.2973
527 1ZJ6 G3D 0.0000001087 0.60988 37.4332
528 1YZN GNP 0.00000002573 0.52815 37.4359
529 1YZG GDP 0.0000002286 0.59617 38.5475
530 3W5J GDP 0.000000477 0.50489 38.9744
531 2WJG GDP 0.0000001844 0.62979 39.3617
532 4ZI2 GNP 0.00000001884 0.57743 39.4737
533 2D7C GTP 0.00000005345 0.66082 39.521
534 1KMQ GNP 0.00000003547 0.66357 39.6739
535 4GOJ GNP 0.00000003822 0.65906 39.6825
536 4B47 GDP 0.000000002905 0.64631 40
537 3A1S GDP 0.0000000005862 0.7066 41.0256
538 1FZQ GDP 0.000000004441 0.65322 41.4365
539 3BC1 GNP 0.00000001077 0.69361 41.5385
540 2EW1 GNP 0.0000000217 0.67353 42.5641
541 1S9D GDP 0.0000004586 0.6019 43.9024
542 1RE0 GDP 0.00000005661 0.59716 43.9024
543 2J59 GTP 0.0000007758 0.60104 43.9759
544 1O3Y GTP 0.000001028 0.59534 43.9759
545 1J2J GTP 0.0000001434 0.53658 43.9759
546 2GJ8 ALF GDP 0.0000000002556 0.59243 44.186
547 2WJH GDP 0.0000002011 0.59919 44.5783
548 2WJH FLC 0.00003461 0.50871 44.5783
549 5M04 GDP 0.000000008515 0.70489 48.7179
550 1Y3A GDP 0.0000123 0.54503 50
Pocket No.: 2; Query (leader) PDB : 3PQC; Ligand: GDP; Similar sites found: 63
This union binding pocket(no: 2) in the query (biounit: 3pqc.bio2) has 14 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4K26 NDP 0.01923 0.42221 None
2 2X6T NAP 0.04532 0.40097 1.02564
3 4KOT CE3 0.02869 0.41913 1.85185
4 1H9A NAP 0.0487 0.40355 2.05128
5 1S7N COA 0.01233 0.41807 2.1978
6 1KUV CA5 0.01532 0.4275 2.5641
7 1GHE ACO 0.02813 0.40428 2.82486
8 2B4D COA 0.02398 0.40319 2.92398
9 1CJW COT 0.008807 0.43647 3.01205
10 3RC3 ANP 0.002203 0.43987 3.07692
11 2D2F ADP 0.0002443 0.42885 3.07692
12 4QDI ATP 0.0178 0.40013 3.07692
13 2JDC CAO 0.02389 0.41349 3.42466
14 2R42 FPS 0.01359 0.41589 3.5443
15 3BD9 A3P 0.002168 0.4456 3.58974
16 4IXH IMP 0.009354 0.42925 3.58974
17 2V2V V12 0.0225 0.42775 3.58974
18 4X1Z FUC GAL NDG 0.006832 0.42373 3.58974
19 1ZRH A3P 0.01439 0.41462 3.58974
20 5HGZ ACO 0.01739 0.41669 4.10256
21 5EP2 AZU 0.01027 0.42214 4.29688
22 2CNT COA 0.03065 0.40232 4.375
23 4E5N NAD 0.02913 0.41362 4.61538
24 1W5F G2P 0.02225 0.41248 5.12821
25 2VOS ADP 0.02731 0.4019 5.12821
26 3R96 AMP 0.03293 0.41487 5.31915
27 3R96 ACO 0.03293 0.41487 5.31915
28 4W93 3L9 0.02716 0.41527 5.64103
29 3TO7 COA 0.02182 0.41152 5.64103
30 4KVX ACO 0.006117 0.44194 5.76923
31 5H86 BCO 0.03407 0.40527 5.95238
32 4ITM ATP 0.007418 0.43605 6.15385
33 4TM3 FAD 0.03478 0.43444 6.15385
34 5BUK FAD 0.04385 0.41417 6.15385
35 3D2M COA 0.02746 0.41151 6.15385
36 1WWZ ACO 0.02708 0.41059 6.28931
37 1J99 AND 0.019 0.42364 6.66667
38 1QSN COA 0.0165 0.40979 6.79012
39 1Q2D COA 0.01709 0.40717 6.79012
40 3X0D SAH 0.02029 0.40693 7.17949
41 2ZPA ACO 0.02916 0.40197 7.17949
42 4HUT ATP 0.0168 0.42291 7.32984
43 2VHJ ADP 0.01797 0.40965 7.69231
44 3EWC MCF 0.03601 0.40005 7.69231
45 4AVB ACO 0.03026 0.40404 8.20513
46 1QHH ATP 0.006117 0.42324 8.87574
47 1QHG ATP 0.006289 0.42713 9.23077
48 4PSW COA 0.006384 0.4268 10.2564
49 1GQY ACP 0.01835 0.40366 10.2564
50 3F8K COA 0.0151 0.41841 10.625
51 5HR5 FLC 0.01239 0.43243 10.7692
52 1Q19 APC 0.01419 0.41663 10.7692
53 1JBW ACQ 0.04225 0.40375 10.7692
54 1P3D ANP 0.02384 0.40332 10.7692
55 2OG2 MLI 0.00001451 0.43526 11.2821
56 4AF0 IMP 0.007911 0.4314 11.2821
57 2YNC YNC 0.04902 0.40438 11.2821
58 3ZL8 ADP 0.02482 0.40242 12.8205
59 2X7I CIT 0.002939 0.43648 13.3333
60 3SXN COA 0.005561 0.43759 14.359
61 1W78 PD8 0.04169 0.41018 14.8718
62 1W78 ADP 0.0203 0.41018 14.8718
63 3V2U ATP 0.009545 0.42551 15.8974
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