Receptor
PDB id Resolution Class Description Source Keywords
3RDV 1.75 Å NON-ENZYME: OTHER STRUCTURE OF THE SLAIN2C-CLIPCG1 COMPLEX HOMO SAPIENS CYTOSKELETAL PROTEIN CAP GLY PROTEIN COMPLEX STRUCTURAL PR
Ref.: SLAIN2 LINKS MICROTUBULE PLUS END-TRACKING PROTEINS CONTROLS MICROTUBULE GROWTH IN INTERPHASE J.CELL BIOL. V. 193 1083 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ASP SER TRP LYS ASP GLY CYS TYR E:574;
F:574;
G:575;
H:574;
 Valid;
Valid;
Valid;
Valid;
 none;
none;
none;
none;
 submit data
972.023 n/a SCC(N...
BME C:1;
 Invalid;
 none;
 submit data
78.133 C2 H6 O S C(CS)...
NA A:1;
 Invalid;
 none;
 submit data
22.99 Na [Na+]
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3RDV 1.75 Å NON-ENZYME: OTHER STRUCTURE OF THE SLAIN2C-CLIPCG1 COMPLEX HOMO SAPIENS CYTOSKELETAL PROTEIN CAP GLY PROTEIN COMPLEX STRUCTURAL PR
Ref.: SLAIN2 LINKS MICROTUBULE PLUS END-TRACKING PROTEINS CONTROLS MICROTUBULE GROWTH IN INTERPHASE J.CELL BIOL. V. 193 1083 2011
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 3RDV - ASP SER TRP LYS ASP GLY CYS TYR n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 3RDV - ASP SER TRP LYS ASP GLY CYS TYR n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 3RDV - ASP SER TRP LYS ASP GLY CYS TYR n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: ASP SER TRP LYS ASP GLY CYS TYR; Similar ligands found: 91
No: Ligand ECFP6 Tc MDL keys Tc
1 ASP SER TRP LYS ASP GLY CYS TYR 1 1
2 ILE ASP TRP PHE ASP GLY LYS ASP 0.593103 0.809524
3 ILE ASP TRP PHE ASP GLY LYS GLU 0.583893 0.809524
4 ASP GLU ASP LYS TRP ASP ASP PHE 0.58209 0.847458
5 MET LEU ILE TYR SER MET TRP GLY LYS 0.574074 0.852941
6 ILE ASP TRP PHE GLU GLY LYS GLU 0.562914 0.78125
7 GLU ASN ASP LYS TRP ALA SER 0.551724 0.868852
8 GLU LEU ASP LYS TRP ALA SER 0.541096 0.825397
9 TYR MET TRP ASP GLY TRP TYR MET QJE 0.540881 0.814286
10 GLU GLN ASP LYS TRP ALA SER 0.537415 0.852459
11 ASP ASN TRP GLN ASN GLY THR SER 0.537415 0.868852
12 LEU GLU LEU ASP LYS TRP ALA SER LEU 0.532895 0.84127
13 GLU ALA ASP LYS TRP GLN SER 0.530612 0.852459
14 ARG PHE MET ASP TYR TRP GLU GLY LEU 0.526946 0.75
15 GLU GLU TYR LEU LYS ALA TRP THR PHE 0.515152 0.859375
16 ALA LEU ASP LYS TRP ASP 0.510791 0.777778
17 ALA LEU ASP LYS TRP ALA SER 0.510345 0.825397
18 GLU LEU ASP LYS TRP ALA GLY 0.510204 0.75
19 PHE GLN TRP MET GLY TYR GLU LEU TRP 0.509202 0.791045
20 SER SER VAL VAL GLY VAL TRP TYR LEU 0.506579 0.857143
21 GLU LEU ASP ORN TRP ALA SER 0.503356 0.809524
22 GLU LEU GLU LYS TRP ALA SER 0.5 0.78125
23 ASN ASP TRP LEU LEU PRO SER TYR 0.497006 0.816901
24 GLU LEU ASP LYS TRP ALA ASN 0.496689 0.78125
25 ASP PHE GLU LYS GLU GLY TYR SER LEU 0.493506 0.8125
26 GLN ALA SER GLN ASP VAL LYS ASN TRP 0.490566 0.828125
27 SER VAL TYR ASP PHE PHE VAL TRP LEU 0.490196 0.84127
28 SER SER VAL ILE GLY VAL TRP TYR LEU 0.487342 0.84375
29 LYS TRP LYS 0.484375 0.766667
30 MET LEU TRP GLY TYR LEU GLN TYR VAL 0.48125 0.80303
31 GLY LEU MET TRP LEU SER TYR PHE VAL 0.481013 0.848485
32 CYS THR GLU LEU LYS LEU SER ASP TYR 0.476821 0.793651
33 GLU LEU ARG SER ARG TYR TRP ALA ILE 0.47619 0.788732
34 ASN ASP LYS TYR GLU PRO PHE TRP GLU 0.472222 0.835821
35 GLN ALA SER GLN GLU VAL LYS ASN TRP 0.47205 0.828125
36 ASP ASN ARG LEU GLY LEU VAL TYR TRP PHE 0.471014 0.725806
37 GLY LYS ILE SER LYS HIS TRP THR GLY ILE 0.470588 0.833333
38 GLY SER HIS LEU GLU VAL GLN GLY TYR TRP 0.468571 0.848485
39 ARG TYR PRO LEU THR LEU GLY TRP CYS PHE 0.465608 0.763158
40 VAL GLY LEU TRP LYS SER 0.464789 0.707692
41 GLU LEU ASP HOX TRP ALA SER 0.464516 0.769231
42 ASP TRP ASN 0.460938 0.733333
43 VAL CYS TRP GLY GLU LEU MET ASN LEU 0.460123 0.761194
44 VAL ASP SER LYS ASN THR SER SER TRP 0.458599 0.857143
45 ILE ARG TYR PRO LYS THR PHE GLY TRP 0.455026 0.736842
46 MET TYR TRP TYR PRO TYR 0.45283 0.732394
47 GLU LEU ASP NRG TRP ALA SER 0.451219 0.64557
48 GAL TRP LYS TYR LEU PHB 0.449367 0.846154
49 ALA SER ASN GLU ASN TRP GLU THR MET 0.445161 0.80303
50 PRO GLY LEU TRP LYS SER 0.445161 0.75
51 LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS 0.445087 0.694444
52 SER ARG ARG TRP ARG ARG TRP ASN ARG 0.442177 0.791045
53 TYR GLU TRP 0.441176 0.79661
54 GLU LEU ASP LYS TYR ALA SER 0.439189 0.761905
55 LYS ARG TRP ILE ILE MET GLY LEU ASN LYS 0.438889 0.68
56 ASP ASP ASP ASP TYR 0.438017 0.661017
57 LYS ARG LYS SER ARG TRP ASP GLU THR PRO 0.437158 0.743243
58 THR SER ASN LEU GLN GLU GLN ILE GLY TRP 0.434524 0.830769
59 ASP TRP GLU ILE VAL 0.434483 0.671875
60 GLU LEU ASP HIS TRP ALA SER 0.433962 0.742424
61 LYS GLN TRP LEU VAL TRP LEU PHE LEU 0.432099 0.75
62 MET SER LEU PRO GLY ARG TRP LYS PRO LYS 0.431579 0.696203
63 ARG ARG LYS TRP ARG ARG TRP HIS LEU 0.43125 0.676056
64 ARG ARG LYS TRP CIR ARG TRP HIS LEU 0.429448 0.666667
65 ALA ASN SER ARG TRP GLN ASP THR ARG LEU 0.429412 0.746479
66 GLY GLU GLU GLU GLY GLU CYS TYR 0.426471 0.779661
67 ARG PHE PRO LEU THR PHE GLY TRP CYS PHE 0.426316 0.736842
68 8LR GLY TRP TYR XSN 0.425 0.802817
69 SER ARG TYR TRP ALA ILE ARG THR ARG 0.424419 0.785714
70 ACE GLU TRP TRP TRP 0.424242 0.677419
71 GLU ASN GLN LYS GLU TYR PHE PHE 0.423611 0.786885
72 CYS THR GLU LEU LYS LEU ASN ASP TYR 0.423077 0.765625
73 PCA LYS TRP 0.41844 0.816667
74 ACE ASN TRP GLU THR PHE 0.418301 0.777778
75 LEU GLU LYS ALA ARG GLY SER THR TYR 0.417647 0.714286
76 SER SER THR ARG GLY ILE SER GLN LEU TRP 0.417143 0.771429
77 HIS SER LYS LYS LYS CYS ASP GLU LEU 0.415584 0.772727
78 ARG LEU TRP SER 0.414966 0.695652
79 GLU GLN TYR LYS PHE TYR SER VAL 0.414474 0.793651
80 GLY GLY LYS LYS LYS TYR LYS LEU 0.414286 0.703125
81 THR SER THR LEU GLN GLU GLN ILE GLY TRP 0.414201 0.84375
82 ALA LEU ASP LYS TRP GLN ASN 0.412162 0.761905
83 PHE SER ASP PRO TRP GLY GLY 0.407186 0.833333
84 ARG ARG ARG ARG TRP ARG GLU ARG GLN 0.405229 0.701493
85 ASP PHE GLU ASP TYR GLU PHE ASP 0.404255 0.709677
86 ARG TYR PRO LEU THR PHE GLY TRP 0.402116 0.736842
87 GLY GLY LYS LYS LYS TYR GLN LEU 0.401361 0.703125
88 ASP GLU LEU GLU ILE LYS ALA TYR 0.401274 0.692308
89 MET ASP TRP ASN MET HIS ALA ALA 0.4 0.705882
90 GLY SER ASP PRO TRP LYS 0.4 0.818182
91 LYS TRP 0.4 0.745763
Similar Ligands (3D)
Ligand no: 1; Ligand: ASP SER TRP LYS ASP GLY CYS TYR; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3RDV; Ligand: ASP SER TRP LYS ASP GLY CYS TYR; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 3rdv.bio4) has 15 residues
No: Leader PDB Ligand Sequence Similarity
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