Receptor
PDB id Resolution Class Description Source Keywords
3REF 1.95 Å EC: 3.-.-.- CRYSTAL STRUCTURE OF EHRHO1 BOUND TO GDP AND MAGNESIUM ENTAMOEBA HISTOLYTICA CYTOSKELETON NUCLEOTIDE-BINDING GTP-BINDING SIGNALING PROLIPOPROTEIN PRENYLATION
Ref.: UNIQUE STRUCTURAL AND NUCLEOTIDE EXCHANGE FEATURES RHO1 GTPASE OF ENTAMOEBA HISTOLYTICA. J.BIOL.CHEM. V. 286 39236 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP A:274;
B:274;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
MG A:192;
B:550;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
SO4 A:193;
A:194;
B:192;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3REF 1.95 Å EC: 3.-.-.- CRYSTAL STRUCTURE OF EHRHO1 BOUND TO GDP AND MAGNESIUM ENTAMOEBA HISTOLYTICA CYTOSKELETON NUCLEOTIDE-BINDING GTP-BINDING SIGNALING PROLIPOPROTEIN PRENYLATION
Ref.: UNIQUE STRUCTURAL AND NUCLEOTIDE EXCHANGE FEATURES RHO1 GTPASE OF ENTAMOEBA HISTOLYTICA. J.BIOL.CHEM. V. 286 39236 2011
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 218 families.
1 3REF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 3REG - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 176 families.
1 3REF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 3REG - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 143 families.
1 2W2T - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 2WKR - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
3 3REF - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 5A0F - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3REF; Ligand: GDP; Similar sites found: 459
This union binding pocket(no: 1) in the query (biounit: 3ref.bio2) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5BQ5 ADP BEF 0.000189 0.48758 None
2 4QM7 GTP 0.0001246 0.41849 None
3 1LVG ADP 0.00003318 0.4183 None
4 3VZS NAP 0.01379 0.4108 1.03093
5 2ZPA ADP 0.0007278 0.42601 1.54639
6 4ZNL BEF ADP 0.000238 0.41792 1.54639
7 1DAK DPU 0.000192 0.49091 2.06186
8 1DAK ADP 0.006233 0.45082 2.06186
9 3FB4 AP5 0.004979 0.42518 2.06186
10 3W5J GDP 0.00000712 0.4245 2.06186
11 1JI0 ATP 0.00004692 0.54399 2.57732
12 5J1J ANP 0.0002933 0.4569 2.57732
13 3E70 GDP 0.00002911 0.45428 2.57732
14 2OFW ADX 0.001318 0.44988 2.57732
15 1X6V ADP 0.001024 0.44264 2.57732
16 2QZ4 ADP 0.0001011 0.43885 2.57732
17 1XMV ADP 0.0001342 0.42472 2.57732
18 3BFV ADP 0.0003415 0.40506 2.57732
19 2PEZ DAT 0.001378 0.44143 2.7933
20 2PEZ GGZ 0.001378 0.44143 2.7933
21 4R98 GNH 0.000000886 0.50207 3.09278
22 1Z6T ADP 0.0002412 0.47223 3.09278
23 3DC4 ADP 0.000001288 0.46502 3.09278
24 2C04 GCP 0.0004707 0.45934 3.09278
25 1ZIN AP5 0.001287 0.4515 3.09278
26 4MKG AP5 0.00381 0.43039 3.09278
27 4E03 ADP 0.0001221 0.43005 3.09278
28 1NHX FTB 0.004843 0.42973 3.09278
29 1NHX PEP 0.004724 0.42925 3.09278
30 1T5C ADP 0.000001073 0.4261 3.09278
31 3BOS CDP 0.0001337 0.41753 3.09278
32 1NY5 ADP 0.0009899 0.41611 3.09278
33 2GMV UN8 0.005135 0.41104 3.09278
34 2GMV PEP 0.007734 0.40615 3.09278
35 1W5T ANP 0.003714 0.40421 3.09278
36 4WOP CTP 0.0001316 0.46328 3.11111
37 4J0Q GDP 0.00000001329 0.71342 3.60825
38 2ZFI ADP 0.000006619 0.57036 3.60825
39 1D2E GDP 0.00000009493 0.55899 3.60825
40 4LPS GDP 0.00000004512 0.55035 3.60825
41 3TK1 GDP 0.00000003417 0.51843 3.60825
42 1V8K ANP 0.000007102 0.46595 3.60825
43 3IO3 ADP 0.0003207 0.44107 3.60825
44 2XT3 ADP 0.000001044 0.43906 3.60825
45 2VVG ADP 0.0000003468 0.43774 3.60825
46 2FAH GDP 0.0002301 0.43738 3.60825
47 5G41 AP5 0.00367 0.43615 3.60825
48 5LTJ ADP 0.0002393 0.41643 3.60825
49 1G0N PHH 0.01026 0.41399 3.60825
50 1G0N NDP 0.009211 0.41319 3.60825
51 1UKZ ADP 0.007 0.41185 3.60825
52 3EWA ANP 0.0001803 0.41174 3.60825
53 2IS6 ADP 0.0002126 0.40996 3.60825
54 1JJ7 ADP 0.000003384 0.40858 3.60825
55 2VOH CIT 0.007141 0.4221 3.82166
56 1SVK ALF GDP 0.0000004222 0.59041 4.12371
57 1TQ4 GDP 0.0000003605 0.58299 4.12371
58 1BH2 GSP 0.0000007868 0.5766 4.12371
59 5HCN GCP 0.00000007331 0.55032 4.12371
60 2OM2 GDP 0.000007611 0.52664 4.12371
61 1Y3A GDP 0.000007416 0.52386 4.12371
62 4ZG4 VO4 ADP 0.00002149 0.50449 4.12371
63 5I0H ADP BEF 0.00001252 0.50438 4.12371
64 2Q2Y ADP 0.0005836 0.46686 4.12371
65 2Q2Y MKR 0.000578 0.46584 4.12371
66 1FNN ADP 0.0003561 0.46005 4.12371
67 5VGR GDP 0.0005253 0.45723 4.12371
68 4LYA ATP 0.00003275 0.45352 4.12371
69 1YTM ATP 0.0005192 0.44863 4.12371
70 3UIE ANP 0.00007222 0.44329 4.12371
71 3COB ADP 0.000001088 0.4398 4.12371
72 4X8O AP5 0.003435 0.43746 4.12371
73 1BG2 ADP 0.0000004258 0.43617 4.12371
74 4XGU ADP 0.0003415 0.4344 4.12371
75 4D81 ADP 0.0002375 0.43114 4.12371
76 5IFS ADP 0.0003042 0.42079 4.12371
77 3QXC ATP 0.003525 0.41652 4.12371
78 1G3Q ADP 0.0003134 0.4154 4.12371
79 4IHQ ADP 0.0001419 0.40977 4.12371
80 2XAU ADP 0.0006963 0.40754 4.12371
81 3S5W FAD 0.01091 0.40218 4.12371
82 5THQ NDP 0.005251 0.41478 4.41176
83 1B7T ADP 0.0005558 0.41242 4.48718
84 1B0U ATP 0.001105 0.40499 4.58015
85 3KTA AP5 0.0007725 0.41222 4.62428
86 4DCT GDP 0.000000007667 0.57533 4.63918
87 4B47 GDP 0.00000002068 0.54084 4.63918
88 4QOS ADP 0.0005281 0.46686 4.63918
89 2BIF SIN 0.001146 0.45706 4.63918
90 2BIF ANP 0.0006504 0.45706 4.63918
91 2IYL GDP 0.00002018 0.45314 4.63918
92 1NJF AGS 0.000686 0.43947 4.63918
93 2Y65 ADP 0.000001515 0.43697 4.63918
94 1T8U UAP SGN IDS SGN 0.003112 0.43432 4.63918
95 1NJF ADP 0.0005044 0.43261 4.63918
96 4V03 ADP 0.0001569 0.4321 4.63918
97 1SVM ATP 0.005011 0.43181 4.63918
98 5H56 ADP 0.002122 0.43047 4.63918
99 5H56 TYD 0.002122 0.43047 4.63918
100 4FRZ ADP 0.000006621 0.43026 4.63918
101 1OS1 PYR 0.002799 0.42527 4.63918
102 4MKF AP5 0.005228 0.42526 4.63918
103 1OS1 ATP 0.002778 0.42397 4.63918
104 4YDS ATP 0.0000344 0.41767 4.63918
105 4GBM A3P 0.00344 0.41205 4.63918
106 1G6H ADP 0.000004121 0.40637 4.63918
107 1QF9 C5P 0.01186 0.40515 4.63918
108 1QF9 ALF 0.01186 0.40515 4.63918
109 1QF9 ADP 0.01186 0.40515 4.63918
110 1RRC ADP 0.00001747 0.40276 4.63918
111 2CBZ ATP 0.000002436 0.63171 5.15464
112 2C78 GNP 0.00000002331 0.62573 5.15464
113 2C77 GNP 0.00000001507 0.62394 5.15464
114 5GOE GDP 0.0000005285 0.52395 5.15464
115 3FKQ ATP 0.00004637 0.50402 5.15464
116 5FTB ANP 0.000613 0.46385 5.15464
117 5FHD ADP ALF 0.0004421 0.4516 5.15464
118 2FNA ADP 0.0004139 0.44862 5.15464
119 2BEK ATP 0.0005785 0.44256 5.15464
120 3RLF ANP 0.00105 0.43368 5.15464
121 1G41 ADP 0.0002461 0.42537 5.15464
122 2AWN ADP 0.0000003813 0.41607 5.15464
123 1D2N ANP 0.003044 0.40757 5.15464
124 4PPF FLC 0.000003031 0.40309 5.15464
125 1ZUI SKM 0.0001093 0.49394 5.35714
126 2QQ0 ANP 0.003037 0.42646 5.43478
127 2QQ0 TMP 0.003124 0.42592 5.43478
128 2QQ0 THM 0.002819 0.42513 5.43478
129 3ZQ6 ADP ALF 0.0001252 0.4783 5.55556
130 5MVR ADP 0.000129 0.42112 5.55556
131 3U6B GDP 0.000000008948 0.722 5.6701
132 2BVN GNP 0.000000001998 0.70789 5.6701
133 1WDT GTP 0.0000003823 0.58903 5.6701
134 2HCJ GDP 0.000000004652 0.55572 5.6701
135 5JBQ GDP 0.00000001817 0.55053 5.6701
136 1D8T GDP 0.00000001843 0.55051 5.6701
137 3U6K GDP 0.00000001945 0.55031 5.6701
138 4G5G GDP 0.00000001824 0.5503 5.6701
139 4P3Y GDP 0.00000001225 0.5451 5.6701
140 3CNL GNP 0.00000002984 0.5357 5.6701
141 1KK1 GNP 0.00000006116 0.52719 5.6701
142 3EZ2 ADP 0.00009967 0.51987 5.6701
143 4IDN GNP 0.0002798 0.45571 5.6701
144 1UJ2 ADP 0.001148 0.4373 5.6701
145 4RZ3 ADP 0.0003568 0.43472 5.6701
146 2ZTS ADP 0.001675 0.43082 5.6701
147 1UJ2 C5P 0.00166 0.43047 5.6701
148 2CE7 ADP 0.0001813 0.42846 5.6701
149 1M2Z BOG 0.01276 0.42835 5.6701
150 3QKT ANP 0.001776 0.42588 5.6701
151 1NN5 ANP 0.003021 0.42522 5.6701
152 3B5J 12D 0.00006235 0.41127 5.6701
153 5LB3 ADP 0.0002235 0.40966 5.6701
154 1NRJ GTP 0.00000002499 0.61603 5.6962
155 3H86 AP5 0.002354 0.43388 5.72917
156 4NCN GTP 0.000000007191 0.65019 6.18557
157 2WIC GNP 0.0000002415 0.63086 6.18557
158 3VMF GTP 0.00000005894 0.61744 6.18557
159 3CX8 GSP 0.0000002605 0.59725 6.18557
160 2QN6 GDP 0.000000003977 0.55794 6.18557
161 3WYA GDP 0.0000000159 0.55282 6.18557
162 3WY9 GDP 0.000000008864 0.54984 6.18557
163 5L3W GDP 0.00003916 0.45711 6.18557
164 3KJI ADP 0.0002481 0.4349 6.18557
165 3FVQ ATP 0.001298 0.42225 6.18557
166 3TMK T5A 0.003535 0.41946 6.18557
167 3FYH ADP 0.003562 0.41311 6.18557
168 3B7G ANP 0.0005387 0.41047 6.18557
169 5X40 ACP 0.002334 0.41912 6.50685
170 4RD0 GDP 0.000000001929 0.67084 6.70103
171 1IWE IMP 0.001348 0.48707 6.70103
172 4OHY ANP 0.00008655 0.46062 6.70103
173 1IHU AF3 0.0004344 0.44774 6.70103
174 1IHU ADP 0.0004849 0.44774 6.70103
175 3LRE ADP 0.000001219 0.4256 6.70103
176 1ION ADP 0.0003333 0.42104 6.70103
177 2VF7 ADP 0.0005554 0.40362 6.70103
178 1M2O GNP 0.00000001069 0.64887 6.84211
179 4OI4 ATP 0.002019 0.42177 6.95652
180 4ZKD GDP 0.000000009 0.65482 7.2165
181 2HF9 GSP 0.0000008972 0.58006 7.2165
182 4PC3 GDP 0.0000005219 0.5351 7.2165
183 2DPY ADP 0.00009138 0.52915 7.2165
184 1DAR GDP 0.0000002857 0.51842 7.2165
185 3Q9L ATP 0.0001169 0.45389 7.2165
186 1S3G AP5 0.004779 0.42598 7.2165
187 1XKV ATP 0.0004584 0.41572 7.2165
188 4YMU ATP 0.00007531 0.41546 7.2165
189 4IOK ADP 0.005468 0.40987 7.2165
190 4IOK XPO 0.005001 0.40689 7.2165
191 3CV2 OXL 0.02537 0.40268 7.2165
192 1R0X ATP 0.0005161 0.40188 7.2165
193 3IIJ ADP 0.00004209 0.43211 7.22222
194 1F2U ATP 0.002691 0.42153 7.38255
195 2RCN GDP 0.000000001136 0.59243 7.73196
196 4P4T GDP 0.0000009703 0.57146 7.73196
197 4WZA ADP 0.00009497 0.52142 7.73196
198 4WZA ACP 0.00009879 0.52062 7.73196
199 5M04 GDP 0.0000001567 0.51487 7.73196
200 3ZFD ANP 0.000009085 0.48014 7.73196
201 2CHG ANP 0.000151 0.44722 7.73196
202 1M7G ADX 0.001049 0.44517 7.73196
203 1M7G ADP 0.0009713 0.44362 7.73196
204 2JLR ANP 0.000143 0.44076 7.73196
205 1FP6 ADP 0.0001635 0.43814 7.73196
206 1M7G AV2 0.00004221 0.42662 7.73196
207 4FCW ADP 0.0006527 0.40652 7.73196
208 2WHX ADP 0.00006923 0.40109 7.73196
209 3P4X ADP 0.0000612 0.42189 7.74818
210 2QTV GNP 0.00000002745 0.62871 7.78443
211 5J1S ATP 0.004015 0.41092 8.13008
212 3H4S ADP 0.000001343 0.43633 8.14815
213 5KDO GDP 0.0000117 0.50723 8.23529
214 5GJC ATP 0.00003348 0.43942 8.24742
215 2QG6 NMN 0.005159 0.41095 8.24742
216 4U00 ADP 0.000003792 0.40736 8.24742
217 1PUJ GNP 0.00000002697 0.58247 8.76289
218 5L3S GNP 0.0001034 0.47795 8.76289
219 4IEE AGS 0.0008451 0.4735 8.76289
220 5L3V GDP 0.00002102 0.46603 8.76289
221 1QF5 GDP 0.00162 0.45611 8.76289
222 4HSE ADP 0.00008037 0.43314 8.76289
223 5XDR ADP 0.0004797 0.40638 8.76289
224 1HTW ADP 0.00008125 0.43582 8.86076
225 2KIN ADP 0.0000002511 0.44009 9
226 1F6B GDP 0.0000008697 0.5142 9.27835
227 1SQ5 ADP 0.0001295 0.50115 9.27835
228 2C9O ADP 0.00112 0.43443 9.27835
229 3BER AMP 0.006294 0.42527 9.27835
230 1OXV ANP 0.00007149 0.41519 9.27835
231 4P32 ADP 0.003245 0.41132 9.27835
232 1XP8 AGS 0.0001742 0.40923 9.27835
233 1P9B GDP 0.002522 0.40429 9.27835
234 1AZT GSP 0.0000001406 0.60877 9.79381
235 3AB3 GDP 0.000001344 0.54519 9.79381
236 1CS4 GSP 0.0000001938 0.5405 9.79381
237 1ZCB GDP 0.000005153 0.53514 9.79381
238 1W0J ADP 0.00007676 0.45108 9.79381
239 5TSH ANP 0.00004839 0.43239 9.79381
240 1W0J ADP BEF 0.000636 0.42938 9.79381
241 5TSH ADP 0.00003319 0.41248 9.79381
242 4QRH 0O2 0.004352 0.4006 9.79381
243 3PQC GDP 0.000000006714 0.69412 10.3093
244 2NCD ADP 0.000004312 0.60485 10.3093
245 3NHB ADP 0.00002582 0.56501 10.3093
246 5K5Z ANP 0.0001436 0.47194 10.3093
247 1F5N GNP 0.00002726 0.46473 10.3093
248 4Q1A 2XZ 0.01589 0.44714 10.3093
249 4Q1A UDP 0.01589 0.44714 10.3093
250 5N69 ADP 0.0002733 0.42911 10.3093
251 5I34 GDP 0.0004084 0.41756 10.3093
252 1W7J ADP BEF 0.0002784 0.46947 10.596
253 2ODE ALF GDP 0.0000003202 0.59339 10.6383
254 1G7C 5GP 0.000001939 0.48702 10.6383
255 4R43 GDP 0.0001253 0.50817 10.8247
256 5IRN ADP 0.0001428 0.43952 10.8247
257 1IN4 ADP 0.0006509 0.42793 10.8247
258 4GOX A3P 0.001709 0.4248 10.8247
259 2J5V PCA 0.03869 0.40975 10.8247
260 1KO8 6PG 0.001497 0.41387 10.8571
261 4H1V GNP 0.000002953 0.5571 11.3402
262 5HR5 ADP 0.000369 0.43054 11.3402
263 4PX9 ADP 0.001689 0.4006 11.3402
264 4CVN ADP 0.00001834 0.56491 11.6788
265 4TMZ GSP 0.00000000629 0.65263 11.8557
266 1SKQ GDP 0.0000000431 0.52878 11.8557
267 2OZE AGS 0.00006921 0.46783 11.8557
268 1K6M AGS 0.001252 0.43047 11.8557
269 2ZR9 DTP 0.00006206 0.42918 11.8557
270 5M7P ADP 0.001582 0.4142 11.8557
271 5TIV A3P 0.01262 0.40991 11.8557
272 1L2T ATP 0.002215 0.40524 11.8557
273 1FQJ ALF 0.00001341 0.57664 11.9048
274 1FQJ GDP 0.000003642 0.52465 11.9048
275 2V7Q ATP 0.00004355 0.45197 12
276 2CK3 ANP 0.0006792 0.44787 12
277 2CK3 ADP 0.0006503 0.43332 12
278 2V7Q ADP 0.0001256 0.42289 12
279 3QF7 ANP 0.001893 0.40988 12
280 3T34 GDP 0.00002945 0.48824 12.3711
281 3DZD ADP 0.0008156 0.41553 12.3711
282 2PZE ATP 0.0000146 0.40555 12.8866
283 3WXM GTP 0.00000006078 0.61687 13.4021
284 2W58 ADP 0.000001298 0.41844 13.4021
285 1KK8 BEF ADP 0.0004251 0.42899 14.2857
286 4M9Q GNP 0.00000001314 0.63611 14.433
287 2XTZ GSP 0.0000001269 0.60333 14.433
288 1H65 GDP 0.000004876 0.52901 14.433
289 3DEF GDP 0.000001042 0.52384 14.433
290 3ZIA ADP 0.00008858 0.44873 14.433
291 3ZIA ATP 0.00004498 0.44518 14.433
292 4NON GDP 0.00000003916 0.55647 14.9485
293 2RGX AP5 0.003627 0.43343 14.9485
294 1GXU 2HP 0.000299 0.48518 15.3846
295 2WJG GDP 0.00000004981 0.67377 15.4255
296 1ZD9 GDP 0.0000002404 0.59778 15.4255
297 5CK5 GDP 0.00000004616 0.53181 15.9794
298 1P72 ADP 0.0009649 0.44818 15.9794
299 1G8S MET 0.02426 0.40555 15.9794
300 1YRB GDP 0.00000008829 0.56324 16.4948
301 1Y63 ADP 0.0001026 0.4189 16.8478
302 1G7S GDP 0.0000001988 0.63488 17.0103
303 3B9Q MLI 0.000172 0.52417 17.0103
304 4HI0 GDP 0.00001327 0.51637 17.0103
305 5L3R GCP 0.00002784 0.50198 17.0103
306 4TTQ ATP 0.0004882 0.40523 17.0103
307 2WJH GDP 0.00000007502 0.55036 17.4699
308 2WJH FLC 0.000005845 0.48845 17.4699
309 1MKY GDP 0.000000002382 0.57622 18.0412
310 1OFH ADP 0.0004474 0.41703 18.3908
311 1GOJ ADP 0.0000004472 0.67058 18.5567
312 5IRR GSP 0.0000008654 0.56031 18.5567
313 3BFX A3P 0.002553 0.42287 18.5567
314 4BQS ADP 0.0001234 0.5085 18.75
315 4BQS K2Q 0.002094 0.43736 18.75
316 5DI3 GNP 0.00000002144 0.62724 18.9189
317 4V0K GDP 0.000001203 0.53251 18.9349
318 1CR1 TTP 0.001115 0.42501 19.0722
319 3DOE GTP 0.000000006143 0.65306 19.7917
320 1KSH GDP 0.000000002367 0.65695 19.8925
321 5FG3 GDP 0.00000001217 0.545 20.1031
322 1F9V ADP 0.000002738 0.44157 20.1031
323 3A4M ADP 0.00001778 0.42541 20.3846
324 2FH5 GTP 0.000000004063 0.64705 20.6186
325 3T12 GDP ALF 0.0000003117 0.57879 20.6186
326 3T1O GDP 0.0000008302 0.52086 20.6186
327 1ZJ6 G3D 0.00000004573 0.55248 20.8556
328 1YZG GDP 0.00000004711 0.55185 21.229
329 3FWY ADP 0.00007673 0.45866 22.1649
330 1UPT GTP 0.00000001871 0.62971 22.2222
331 2X77 GDP 0.000000006115 0.58262 22.2222
332 5KSZ GCP 0.00000001714 0.57815 22.6804
333 5EE5 GTP 0.000000005497 0.65188 22.807
334 3PCR GTP 0.00000007537 0.59286 22.8395
335 5KSP GDP 0.00000000811 0.57479 23.1579
336 2A5F GTP 0.0000000101 0.64702 23.4286
337 2J59 GTP 0.00000001538 0.63635 23.494
338 1J2J GTP 0.000000006482 0.63511 23.494
339 1O3Y GTP 0.00000002894 0.62484 23.494
340 1S9D GDP 0.0000003767 0.62169 23.7805
341 1RE0 GDP 0.00000006399 0.52629 23.7805
342 3N5C GDP 0.00000004114 0.67781 24.0741
343 4PFO ADP 0.0002906 0.46092 24.2268
344 1R4A GNP 0.00000001327 0.64201 24.2424
345 4ZI2 GNP 0.000000003648 0.6593 24.7368
346 2WOJ ADP ALF 0.0000759 0.48757 24.7423
347 4XTR ATP 0.0002869 0.4573 24.7423
348 4XVU ATP 0.0003049 0.4562 24.7423
349 3ZS9 ADP ALF 0.00008889 0.44671 24.7423
350 4XTR ADP 0.0003564 0.43976 24.7423
351 4GOJ GNP 0.000000006219 0.64965 24.8677
352 4KAX GTP 0.00000001841 0.63 25.4438
353 2W83 GTP 0.00000001841 0.63307 25.4545
354 3AQ4 GDP 0.0000001107 0.54043 25.5435
355 1FZQ GDP 0.00000002752 0.54875 25.9669
356 2VB6 ADP BEF 0.0008081 0.43844 26.2887
357 5KUT GDP 0.000000004372 0.5825 26.9841
358 1MR3 G3D 0.000000171 0.53257 27.0718
359 4YLG GDP 0.00000008568 0.57397 28.9017
360 2ZEJ GDP 0.000005459 0.53627 29.3478
361 4BAS GNP 0.0000001574 0.59117 29.8969
362 3WYF GTP 0.000000001067 0.69717 30.4124
363 3M1I GTP 0.000000001005 0.69539 30.4124
364 3GJX GTP 0.000000001625 0.68649 30.4124
365 5DIF GNP 0.0000000005453 0.7067 30.9278
366 5UWW GNP 0.0000000005579 0.70627 30.9278
367 5UWP GNP 0.0000000006794 0.70555 30.9278
368 5UWU GNP 0.0000000005872 0.70532 30.9278
369 5UWI GNP 0.0000000006296 0.70404 30.9278
370 5UWO GNP 0.0000000006934 0.70225 30.9278
371 5UWR GNP 0.0000000007193 0.70157 30.9278
372 5UWS GNP 0.0000000008661 0.70104 30.9278
373 4HAT GNP 0.0000000009166 0.69999 30.9278
374 5DI9 GNP 0.0000000009384 0.69955 30.9278
375 5DHF GNP 0.0000000008156 0.69925 30.9278
376 5UWH GNP 0.0000000008249 0.69904 30.9278
377 5UWT GNP 0.0000000008304 0.69891 30.9278
378 3GJ8 GDP 0.00000001307 0.69106 30.9278
379 5UWQ GNP 0.0000000006598 0.6353 30.9278
380 5UWJ GNP 0.0000000006753 0.635 30.9278
381 3GJ5 GDP 0.000000014 0.57021 30.9278
382 3CH5 GDP 0.00000001507 0.56956 30.9278
383 3GJ7 GDP 0.000000009001 0.56402 30.9278
384 3GJ4 GDP 0.00000001202 0.56301 30.9278
385 3GJ3 GDP 0.00000001016 0.56194 30.9278
386 3T5G GDP 0.000000004188 0.59821 31.4917
387 3WYG GTP 0.00000000338 0.67572 32.4176
388 3RWO GDP 0.0000000163 0.64109 32.4324
389 2BCG GDP 0.000000005567 0.66881 32.4742
390 3E5H GNP 0.00000001214 0.64653 33.1461
391 1YZN GNP 0.0000000001249 0.65886 34.0541
392 1WA5 GTP 0.000000001304 0.58254 34.0909
393 1Z06 GNP 0.0000000005008 0.70202 34.3915
394 3A1S GDP 0.00000003444 0.56006 34.5361
395 1VG8 GNP 0.000000001157 0.69278 36.5979
396 1VG0 GDP 0.000000006749 0.60314 36.5979
397 2BME GNP 0.0000000001196 0.73157 38.172
398 2CJW GDP 0.000000002521 0.57987 38.5417
399 1VG9 GDP 0.000000002504 0.59295 38.9189
400 1VG1 GDP 0.000000004816 0.58292 38.9189
401 1Z0K GTP 0.00000000021 0.71452 40.6977
402 2HT6 GDP 0.000000001997 0.57003 40.8046
403 3Q72 GNP 0.0000000008844 0.5799 40.9639
404 3TKL GTP 0.00000000008644 0.73418 41.2371
405 5SZH GNP 0.00000000007616 0.74311 41.7526
406 1OIX GDP 0.0000000009522 0.69338 41.8848
407 2EFE GNH 0.00000002023 0.58607 41.9889
408 3BC1 GNP 0.000000001382 0.68652 42.268
409 2F9L GDP 0.00000001511 0.63667 42.268
410 3CPJ GDP 0.000000006776 0.60442 42.268
411 1OIV GDP 0.000000008182 0.65379 42.4084
412 1ZC3 GNP 0.000000002029 0.68238 42.8571
413 1UAD GNP 0.0000000003268 0.71306 43.4286
414 3SFV GDP 0.00000003086 0.61054 43.6464
415 2EW1 GNP 0.0000000002529 0.71114 43.7811
416 5TAR GDP 0.000000006463 0.68475 43.7838
417 5TB5 GDP 0.00000000265 0.60375 43.7838
418 4DSU GDP 0.000000002384 0.6794 43.8144
419 2A9K GDP 0.00000000128 0.64275 43.8503
420 1TU3 GNP 0.00000000006893 0.74171 43.8596
421 3MJH GTP 0.00000000003297 0.69356 44.0476
422 1R2Q GNP 0.0000000001221 0.75392 44.1176
423 4DKX GDP 0.0000000007716 0.76191 44.3299
424 3Q85 GNP 0.000000002223 0.58114 44.3787
425 5UQW GDP 0.0000000007144 0.69551 44.4444
426 1U8Z GDP 0.0000000006888 0.67339 44.6429
427 5JCZ GDP 0.00000004586 0.59313 45.2514
428 2A5J GDP 0.000000001501 0.72432 45.5497
429 4LX0 BEF GDP 0.00000000007336 0.74381 45.7627
430 2C5L GTP 0.0000000003253 0.71625 46.2428
431 3NKV GNP 0.0000000002765 0.71614 46.2857
432 1Z0J GTP 0.0000000002211 0.65041 46.4706
433 4K81 GTP 0.000000003295 0.6762 46.7836
434 4C4P GNP 0.0000000006543 0.70332 46.8208
435 2Y8E GNP 0.000000001649 0.63089 46.9274
436 3TNF GNP 0.0000000002495 0.72418 47.1264
437 3QBT GNP 0.00000000009067 0.67816 47.1264
438 4LHW GNP 0.000000001018 0.63889 47.1264
439 1KY3 GDP 0.00000001185 0.59444 47.2527
440 1YVD GNP 0.0000000001986 0.72223 47.3373
441 5O2T GSP 0.0000000002702 0.71969 47.3373
442 2FFQ GSP 0.0000000009122 0.69718 47.3684
443 1YZQ GNP 0.0000000009212 0.69699 47.6471
444 1EK0 GNP 0.0000000009198 0.69401 47.6471
445 1Z0A GDP 0.000000003827 0.59977 47.7011
446 1X1R GDP 0.0000000003314 0.71591 47.7528
447 5WDR GNP 0.00000000004515 0.75279 47.9532
448 1CLU DBG 0.000000002414 0.71146 48.1928
449 2UZI GTP 0.0000000008302 0.6959 48.1928
450 5UFQ GNP 0.000000001219 0.68883 48.1928
451 5E95 GDP 0.00000001972 0.59671 48.2143
452 1GWN GTP 0.0000000001474 0.70495 48.4536
453 3DDC GNP 0.0000000001819 0.72701 48.7952
454 3KUD GDP 0.00000001139 0.62785 48.7952
455 5XCO GDP 0.00000001113 0.5937 49.1228
456 1Z0F GDP 0.000000003782 0.5872 49.162
457 1Z08 GNP 0.000000008405 0.63072 49.4118
458 4D0G GTP 0.000000001499 0.6754 49.7143
459 1S8F GDP 0.00000000006698 0.74863 49.7175
460 1M7B GTP 0.00000000005862 0.74416 50
Pocket No.: 2; Query (leader) PDB : 3REF; Ligand: GDP; Similar sites found: 4
This union binding pocket(no: 2) in the query (biounit: 3ref.bio1) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3R7F CP 0.01554 0.41701 4.12371
2 5WRJ A3P 0.005757 0.40431 5.6701
3 4WZ6 ATP 0.00007366 0.40064 7.73196
4 4YS0 ADP 0.00265 0.40128 14.433
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