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Receptor
PDB id Resolution Class Description Source Keywords
3T7S 2.2 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF COMPLEX OF SAM AND BVU_3255, A METHYLTR FROM BACTEROIDES VULGATUS ATCC 8482 BACTEROIDES VULGATUS SMALL MOLECULE METHYLTRANSFERASE BVU_3255 ROSSMANN FOLD METHYLTRASNFERASE SAM METHYLATION TRANSFERASE
Ref.: STRUCTURAL CHARACTERIZATION OF BVU_3255, A METHYLTR FROM HUMAN INTESTINE ANTIBIOTIC RESISTANT PATHOGEN BACTEROIDES VULGATUS J.STRUCT.BIOL. 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAM A:300;
B:300;
C:300;
D:300;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
Ka = 44500 M^-1
398.437 C15 H22 N6 O5 S C[S@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3T7S 2.2 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF COMPLEX OF SAM AND BVU_3255, A METHYLTR FROM BACTEROIDES VULGATUS ATCC 8482 BACTEROIDES VULGATUS SMALL MOLECULE METHYLTRANSFERASE BVU_3255 ROSSMANN FOLD METHYLTRASNFERASE SAM METHYLATION TRANSFERASE
Ref.: STRUCTURAL CHARACTERIZATION OF BVU_3255, A METHYLTR FROM HUMAN INTESTINE ANTIBIOTIC RESISTANT PATHOGEN BACTEROIDES VULGATUS J.STRUCT.BIOL. 2011
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 269 families.
1 3T7S Ka = 44500 M^-1 SAM C15 H22 N6 O5 S C[S@@+](CC....
2 3T7T Ka = 29900 M^-1 SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 237 families.
1 3T7S Ka = 44500 M^-1 SAM C15 H22 N6 O5 S C[S@@+](CC....
2 3T7T Ka = 29900 M^-1 SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 187 families.
1 3T7S Ka = 44500 M^-1 SAM C15 H22 N6 O5 S C[S@@+](CC....
2 3T7T Ka = 29900 M^-1 SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAM; Similar ligands found: 202
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 ADN 0.565789 0.773333
9 RAB 0.565789 0.773333
10 XYA 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 DTA 0.536585 0.789474
21 62X 0.535354 0.884615
22 MTA 0.53012 0.875
23 3DH 0.517647 0.849315
24 5AL 0.510417 0.743902
25 54H 0.510204 0.673913
26 VMS 0.510204 0.673913
27 0UM 0.51 0.857143
28 AMP 0.505747 0.707317
29 LMS 0.505747 0.666667
30 A 0.505747 0.707317
31 ABM 0.505618 0.753086
32 A5A 0.505155 0.688889
33 SON 0.5 0.746988
34 SSA 0.5 0.684783
35 6RE 0.5 0.78481
36 K15 0.5 0.883117
37 5AD 0.5 0.75
38 SRP 0.5 0.746988
39 LSS 0.49505 0.706522
40 CA0 0.494624 0.714286
41 A12 0.494505 0.705882
42 AP2 0.494505 0.705882
43 ME8 0.490385 0.841463
44 TSB 0.49 0.681319
45 53H 0.49 0.666667
46 DAL AMP 0.49 0.765432
47 5CA 0.49 0.684783
48 ACP 0.489362 0.694118
49 ADP 0.48913 0.690476
50 5AS 0.48913 0.648936
51 J7C 0.488889 0.772152
52 A2D 0.488889 0.690476
53 ZAS 0.488636 0.769231
54 9ZD 0.485149 0.729412
55 9ZA 0.485149 0.729412
56 8QN 0.485149 0.743902
57 GAP 0.484536 0.73494
58 AN2 0.483871 0.682353
59 A3S 0.483871 0.813333
60 A7D 0.483871 0.851351
61 GJV 0.483516 0.775
62 SRA 0.483146 0.694118
63 LAD 0.480769 0.752941
64 KAA 0.480769 0.698925
65 GSU 0.480769 0.722222
66 AMO 0.480392 0.746988
67 DSZ 0.480392 0.703297
68 52H 0.48 0.666667
69 M33 0.478723 0.722892
70 BA3 0.478261 0.690476
71 MAO 0.478261 0.82716
72 NEC 0.477778 0.75
73 AOC 0.477778 0.776316
74 DSH 0.477778 0.842105
75 SXZ 0.47619 0.894737
76 AHX 0.475728 0.701149
77 NVA LMS 0.475728 0.736264
78 Y3J 0.47561 0.706667
79 G5A 0.474227 0.684783
80 A3T 0.473684 0.8
81 B4P 0.473118 0.690476
82 AP5 0.473118 0.690476
83 A3N 0.472527 0.766234
84 KB1 0.471698 0.833333
85 PRX 0.46875 0.73494
86 APC 0.46875 0.705882
87 AT4 0.468085 0.686047
88 PAJ 0.466019 0.712644
89 4AD 0.466019 0.759036
90 RBY 0.463918 0.72619
91 ADP PO3 0.463918 0.728395
92 ADV 0.463918 0.72619
93 ADX 0.463158 0.666667
94 MHZ 0.463158 0.82716
95 AU1 0.463158 0.674419
96 YAP 0.462963 0.738095
97 TXA 0.462264 0.72619
98 NB8 0.462264 0.72093
99 A3G 0.461538 0.802632
100 VRT 0.459184 0.842105
101 XAH 0.458716 0.715909
102 YSA 0.458716 0.684783
103 HEJ 0.458333 0.690476
104 50T 0.458333 0.682353
105 ATP 0.458333 0.690476
106 LEU LMS 0.457143 0.717391
107 7D7 0.45679 0.723684
108 KH3 0.455357 0.871795
109 ACQ 0.454545 0.694118
110 AR6 0.453608 0.710843
111 APR 0.453608 0.710843
112 AQP 0.453608 0.690476
113 5FA 0.453608 0.690476
114 NSS 0.451923 0.703297
115 FA5 0.449541 0.746988
116 A5D 0.44898 0.789474
117 AD9 0.44898 0.674419
118 AGS 0.44898 0.678161
119 SAP 0.44898 0.678161
120 PTJ 0.448598 0.72093
121 YLB 0.448276 0.758621
122 YLP 0.447368 0.738636
123 8X1 0.446602 0.680851
124 D3Y 0.446602 0.792208
125 ADP ALF 0.445545 0.678161
126 ALF ADP 0.445545 0.678161
127 3AM 0.444444 0.674699
128 MYR AMP 0.444444 0.776471
129 OAD 0.443396 0.73494
130 2VA 0.443299 0.779221
131 S8M 0.442308 0.831169
132 OOB 0.442308 0.722892
133 TYR AMP 0.441441 0.759036
134 6YZ 0.441176 0.694118
135 ADP VO4 0.441176 0.702381
136 VO4 ADP 0.441176 0.702381
137 T99 0.44 0.686047
138 TAT 0.44 0.686047
139 ANP 0.44 0.674419
140 WAQ 0.439252 0.75
141 B5Y 0.436364 0.717647
142 8PZ 0.436364 0.684783
143 F0P 0.435897 0.844156
144 YLC 0.435897 0.755814
145 AAT 0.435644 0.797468
146 1ZZ 0.435185 0.755814
147 9K8 0.435185 0.663158
148 3OD 0.435185 0.73494
149 NVA 2AD 0.434343 0.855263
150 00A 0.433962 0.689655
151 DLL 0.433962 0.722892
152 ARG AMP 0.433628 0.727273
153 7MD 0.433628 0.715909
154 ATF 0.431373 0.666667
155 SO8 0.43 0.792208
156 3UK 0.429907 0.714286
157 A6D 0.429907 0.72619
158 9X8 0.429907 0.717647
159 F2R 0.429752 0.7
160 5SV 0.428571 0.741176
161 AMP DBH 0.428571 0.714286
162 TYM 0.42735 0.746988
163 WSA 0.42735 0.692308
164 9SN 0.427273 0.681818
165 AHZ 0.426087 0.755814
166 P5A 0.425926 0.691489
167 B5V 0.425926 0.705882
168 PR8 0.425926 0.744186
169 A A 0.425926 0.710843
170 3NZ 0.425926 0.807692
171 A1R 0.424528 0.709302
172 2A5 0.424242 0.674419
173 7MC 0.423729 0.719101
174 B5M 0.423423 0.717647
175 7D5 0.422222 0.658824
176 JB6 0.422018 0.709302
177 FYA 0.422018 0.722892
178 AYB 0.421488 0.75
179 A22 0.419048 0.682353
180 MAP 0.419048 0.659091
181 2AM 0.417582 0.666667
182 TAD 0.417391 0.712644
183 A3P 0.416667 0.686747
184 ADP BMA 0.416667 0.714286
185 25A 0.415094 0.690476
186 YLA 0.413223 0.719101
187 8Q2 0.411765 0.663158
188 A3R 0.411215 0.709302
189 ADQ 0.411215 0.694118
190 48N 0.410256 0.72093
191 0XU 0.41 0.824324
192 GA7 0.408696 0.72619
193 7D3 0.40625 0.643678
194 PAP 0.405941 0.678571
195 DQV 0.405172 0.702381
196 OVE 0.404255 0.662791
197 4UV 0.403509 0.697674
198 AF3 ADP 3PG 0.403361 0.712644
199 3AD 0.402299 0.783784
200 CMP 0.402062 0.691358
201 2BA 0.402062 0.682927
202 7C5 0.4 0.731707
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3T7S; Ligand: SAM; Similar sites found with APoc: 931
This union binding pocket(no: 1) in the query (biounit: 3t7s.bio2) has 21 residues
No: Leader PDB Ligand Sequence Similarity
1 4NTC FAD None
2 2ZFZ ARG None
3 2BOS GLA GAL GLC None
4 1GYY FHC None
5 1LNX URI None
6 1V6A TRE 1.1194
7 2JAH NDP 1.21457
8 2JAP NDP 1.21457
9 5Z2L NDP 1.22449
10 5A9A UTP 1.23457
11 3FPF TNA 1.49254
12 3FPF MTA 1.49254
13 5O42 9JW 1.49254
14 5O42 BGC 1.49254
15 5O42 NAD 1.49254
16 5W7R SAH 1.49254
17 5W7R 9Z7 1.49254
18 3HB5 NAP 1.49254
19 4RF2 NAP 1.49254
20 5EZ7 FAD 1.49254
21 1IY8 NAD 1.49813
22 6HKE MLT 1.57233
23 1JA9 NDP 1.82482
24 1H8P PC 1.83486
25 5YF1 8V0 1.86567
26 5YF1 SFG 1.86567
27 3A25 SAM 1.86567
28 1SB8 NAD 1.86567
29 1SB8 UD2 1.86567
30 4YUW 4JU 1.86567
31 6BQ6 TER 1.86567
32 4YUW S4M 1.86567
33 2YY7 NAD 1.86567
34 3ICT FAD 1.86567
35 3ICS FAD 1.86567
36 3ICR FAD 1.86567
37 3I6I NDP 1.86567
38 3WCZ CIT 1.86567
39 5A04 NDP 1.86567
40 5A04 BGC 1.86567
41 5FTW SAH 1.95312
42 5OVK NDP 1.95312
43 2DKN NAI 1.96078
44 4QED NAP 2.01613
45 4NBT NAD 2.08333
46 4P86 5GP 2.18579
47 1PNO NAP 2.22222
48 1U2Z SAH 2.23881
49 4UCI SAM 2.23881
50 1YXM ADE 2.23881
51 5G3U ITW 2.23881
52 5G3U FDA 2.23881
53 5VN0 FAD 2.23881
54 5VN0 NAI 2.23881
55 1MO9 KPC 2.23881
56 3CGD FAD 2.23881
57 5TTJ FAD 2.23881
58 4JDR FAD 2.23881
59 1MO9 FAD 2.23881
60 3OID NDP 2.23881
61 5U8U FAD 2.23881
62 3CGD COA 2.23881
63 2XVF FAD 2.23881
64 2JHF NAD 2.23881
65 5BRT FAD 2.23881
66 5BRT CH9 2.23881
67 3CGB FAD 2.23881
68 3CGD NAD 2.23881
69 1XHC FAD 2.23881
70 3T31 FAD 2.23881
71 3T31 DCQ 2.23881
72 5JE8 NAD 2.23881
73 1OMO NAD 2.23881
74 5HXI 5HN 2.23881
75 5HXI FAD 2.23881
76 1FEC FAD 2.23881
77 3HSS MLA 2.23881
78 1KYQ NAD 2.23881
79 1WOG 16D 2.23881
80 3LTW HLZ 2.23881
81 5A3B APR 2.23881
82 3GMB FAD 2.23881
83 2ZWI C5P 2.23881
84 2DTX BMA 2.27273
85 1E3W NAD 2.29885
86 1E6W NAD 2.30769
87 4OBW SAM 2.33463
88 3FRH SAH 2.37154
89 4URF NAD 2.41935
90 4TQK NAG 2.46305
91 1UAY ADN 2.47934
92 1JQD SAH 2.61194
93 1JQD HSM 2.61194
94 1YBH FAD 2.61194
95 5BJX UDP 2.61194
96 5BJX NAD 2.61194
97 4ZRN UPG 2.61194
98 4NTD FAD 2.61194
99 4ZRN NAD 2.61194
100 1QO8 FAD 2.61194
101 4ITU NAI 2.61194
102 4ITU 1HS 2.61194
103 4YAG NAI 2.61194
104 4RDI ATP 2.61194
105 4D79 ATP 2.61194
106 2DKH FAD 2.61194
107 2DKH 3HB 2.61194
108 2BGM NAJ 2.61194
109 3E1T FAD 2.61194
110 4FC7 COA 2.61194
111 4FC7 NAP 2.61194
112 4RDH AMP 2.61194
113 3LZW NAP 2.61194
114 3LZW FAD 2.61194
115 6F9Q NAD 2.61194
116 2Q28 ADP 2.61194
117 5LAU AR6 2.61194
118 2IV2 MGD 2.61194
119 2NVK FAD 2.61194
120 3MCT SAH 2.61194
121 1V59 NAD 2.61194
122 1P77 ATR 2.61194
123 5KOX FAD 2.61194
124 5KOX RFP 2.61194
125 3AXB PRO 2.61194
126 3AXB FAD 2.61194
127 4YNU FAD 2.61194
128 3SJU NDP 2.61194
129 4YNU LGC 2.61194
130 1RSG FAD 2.61194
131 1NAA 6FA 2.61194
132 1NAA ABL 2.61194
133 3MAG SAH 2.61194
134 1C0I FAD 2.61194
135 1C0I BE2 2.61194
136 1V59 FAD 2.61194
137 1KOL NAD 2.61194
138 4K5S PM0 2.61194
139 4K5S FAD 2.61194
140 6F3N NAD 2.61194
141 6F3N ADN 2.61194
142 6F3M NAD 2.61194
143 2IV2 2MD 2.61194
144 3AFN NAP 2.61194
145 5JCA FAD 2.61194
146 2RGO FAD 2.61194
147 4IV9 FAD 2.61194
148 5JCA NDP 2.61194
149 3GFB NAD 2.61194
150 1YY5 FAD 2.61194
151 3MCT 3MC 2.61194
152 1HYH NAD 2.61194
153 2WOX NDP 2.61194
154 3Q9T FAY 2.61194
155 2NYA MGD 2.61194
156 4KWI 1TJ 2.6616
157 4KWI NAP 2.6616
158 1ZEM NAD 2.67176
159 3BGD SAH 2.69231
160 3BGD PM6 2.69231
161 1NFQ NAI 2.69231
162 6CI9 NAP 2.7027
163 3GEG NAD 2.83401
164 1X87 NAD 2.90381
165 3ML1 MGD 2.96296
166 2AOT SAH 2.98507
167 3ELW GP3 2.98507
168 3ELW SAM 2.98507
169 4ONQ SFG 2.98507
170 5JJR SAH 2.98507
171 3EVF GTA 2.98507
172 3EVF SAH 2.98507
173 4M37 SAH 2.98507
174 2ZWA SAH 2.98507
175 2WA2 SAM 2.98507
176 2JJQ SAH 2.98507
177 4D5G FAD 2.98507
178 4D5G TPP 2.98507
179 1Y8Q ATP 2.98507
180 2EJU SAH 2.98507
181 3AYI HCI 2.98507
182 3AYI FAD 2.98507
183 2IVD FAD 2.98507
184 1REO FAD 2.98507
185 1GY8 NAD 2.98507
186 1RLZ NAD 2.98507
187 2BRY FAD 2.98507
188 3HDY FDA 2.98507
189 3HDY GDU 2.98507
190 1VKO NAD 2.98507
191 3PPQ CHT 2.98507
192 1PN0 IPH 2.98507
193 1PN0 FAD 2.98507
194 1YQZ FAD 2.98507
195 3FPZ AHZ 2.98507
196 3HDY FAD 2.98507
197 1GTE FAD 2.98507
198 2XVE FAD 2.98507
199 5MLR GRQ 2.98507
200 5MLR NAP 2.98507
201 4TXI FAD 2.98507
202 2AG5 NAD 2.98507
203 2G5C NAD 2.98507
204 3ABI NAD 2.98507
205 3GGO NAI 2.98507
206 3GGO ENO 2.98507
207 1KNR FAD 2.98507
208 4AT0 FAD 2.98507
209 5CUQ NSC 2.99625
210 2BZG SAH 3.01724
211 2CUL FAD 3.01724
212 1H5Q NAP 3.01887
213 2ZAT NAP 3.07692
214 4U8P FDA 3.11891
215 4U8P UDP 3.11891
216 3RJ5 NAD 3.14961
217 1G1T SIA GAL MAG FUC 3.18471
218 3WMX NAD 3.35196
219 1WG8 SAM 3.35821
220 3GCZ SAM 3.35821
221 2GN4 NDP 3.35821
222 2GN4 UD1 3.35821
223 4L2I FAD 3.35821
224 1R6D DAU 3.35821
225 1R6D NAD 3.35821
226 5L95 AMP 3.35821
227 4K26 NDP 3.35821
228 1JQ3 AAT 3.35821
229 1XHL NDP 3.35821
230 4K26 SFF 3.35821
231 1ZQ9 SAM 3.35821
232 5JWC FAD 3.35821
233 2V6G NAP 3.35821
234 5EB4 FAD 3.35821
235 4USQ FAD 3.35821
236 3H8V ATP 3.35821
237 5K4W THR 3.35821
238 5K4W NAI 3.35821
239 5OJ7 AR6 3.35821
240 3LU1 NAD 3.35821
241 1Q1R FAD 3.35821
242 6F7L FAD 3.35821
243 5TOW NAI 3.35821
244 5TOW ADN 3.35821
245 1RYI GOA 3.35821
246 1RYI FAD 3.35821
247 4EIP FAD 3.35821
248 2EXX NAP 3.35821
249 4W6Z 8ID 3.35821
250 3WDM ADN 3.35821
251 3M6W SAM 3.35821
252 2GDZ NAD 3.37079
253 3RFV 15L 3.37079
254 3RFV NAI 3.37079
255 1G60 SAM 3.46154
256 1OAA OAA 3.4749
257 4NBW NAD 3.50195
258 3SQP FAD 3.55649
259 3OJO NAD 3.7123
260 3G2O SAM 3.73134
261 3VSE SAH 3.73134
262 4EUE NAI 3.73134
263 3VYW SAM 3.73134
264 5JAQ NAI 3.73134
265 3TKA SAM 3.73134
266 3C6K SPD 3.73134
267 3QJ4 FAD 3.73134
268 2WPF FAD 3.73134
269 5Z75 NAD 3.73134
270 3C6K MTA 3.73134
271 6F97 FAD 3.73134
272 3GDN HBX 3.73134
273 3GDN FAD 3.73134
274 3X0V FAD 3.73134
275 1BZL GCG 3.73134
276 6B92 SAH 3.73134
277 2ZJ1 ARJ 3.73134
278 2YG3 FAD 3.73134
279 2ZJ1 NAD 3.73134
280 4PIO AVI 3.73134
281 5OC1 FAD 3.73134
282 2WPF WPF 3.73134
283 3WGT FAD 3.73134
284 3WGT QSC 3.73134
285 4PIO SAH 3.73134
286 1BZL FAD 3.73134
287 2E7Z MGD 3.73134
288 5DF1 NAP 3.73134
289 5DF1 58X 3.73134
290 1U8X NAD 3.73134
291 1RPN NDP 3.73134
292 1EK6 UPG 3.73134
293 1EK6 NAI 3.73134
294 2JHP SAH 3.73134
295 1VL8 NAP 3.74532
296 4IQY AR6 3.75
297 3RKR NAP 3.81679
298 1U7T TDT 3.83142
299 2AE2 PTO 3.84615
300 2AE2 NAP 3.84615
301 2RH4 EMO 3.97112
302 5O9F NAD 3.97727
303 5O9F 9ON 3.97727
304 6GFK SAH 3.98406
305 1ZK4 NAP 3.98406
306 4POO SAM 4
307 2CFC KPC 4
308 2CFC NAD 4
309 1M2K APR 4.01606
310 1EDO NAP 4.09836
311 5W7M SAH 4.10448
312 3GWZ SAH 4.10448
313 3GXO SAH 4.10448
314 3EVG SAH 4.10448
315 3L9W AMP 4.10448
316 2P41 SAH 4.10448
317 3L9W GSH 4.10448
318 3FUU ADN 4.10448
319 3U31 NAD 4.10448
320 1XKQ NDP 4.10448
321 4RPL FAD 4.10448
322 4RPL 3UC 4.10448
323 1LVL NAD 4.10448
324 5XLX SAH 4.10448
325 4CNK FAD 4.10448
326 3GF4 FAD 4.10448
327 5NMX FAD 4.10448
328 1H82 FAD 4.10448
329 1MV8 NAD 4.10448
330 5NMX NAP 4.10448
331 1H82 GZZ 4.10448
332 3QVP FAD 4.10448
333 3GF4 UPG 4.10448
334 2UYQ SAM 4.10448
335 5FJN BE2 4.10448
336 5FJN FAD 4.10448
337 1H2B NAJ 4.10448
338 2HK9 ATR 4.10448
339 3NYC IAR 4.10448
340 3NYC FAD 4.10448
341 6FP4 E1T 4.10448
342 6FP4 FAD 4.10448
343 3A4V NAD 4.10448
344 3A4V PYR 4.10448
345 1D1T NAD 4.10448
346 4DSG FAD 4.10448
347 4DSG UDP 4.10448
348 1SZD APR 4.10448
349 5I39 FAD 4.10448
350 2B4Q NAP 4.10448
351 1W8D NAP 4.10448
352 2OD9 A1R NCA 4.10448
353 4O0L NDP 4.10448
354 1GET NAP 4.10448
355 1GET FAD 4.10448
356 4DXD GDP 4.10448
357 2QQF A1R 4.10448
358 1W73 NAP 4.10448
359 6HH6 A3R 4.10448
360 1W6U NAP 4.10448
361 1DLJ UGA 4.10448
362 1MUU NAD 4.10448
363 1EU1 MGD 4.10448
364 1DLJ NAI 4.10448
365 1E1M FAD 4.10448
366 1E1M NAP 4.10448
367 2HK9 NAP 4.10448
368 5XDT GDP 4.10448
369 1LVL FAD 4.10448
370 5XDT MB3 4.10448
371 5GT9 NAP 4.18251
372 2E0N SAH 4.2471
373 4IF4 BEF 4.32692
374 2AQJ TRP 4.46097
375 2AQJ FAD 4.46097
376 3QOX SAH 4.47761
377 5HJM MTA 4.47761
378 1UWK URO 4.47761
379 1UWK NAD 4.47761
380 1EFV FAD 4.47761
381 1EFV AMP 4.47761
382 4KGD FAD 4.47761
383 4KGD TDP 4.47761
384 5K0A FAD 4.47761
385 3DUW SAH 4.47761
386 1UDB UFG 4.47761
387 1UDB NAD 4.47761
388 6FDF SAH 4.47761
389 3GD4 FAD 4.47761
390 3GD4 NAD 4.47761
391 4HA6 FAD 4.47761
392 6GAR FAD 4.47761
393 3K7M FAD 4.47761
394 4Z24 FAD 4.47761
395 4BV6 FAD 4.47761
396 4Y9D NAI 4.47761
397 5JCM NAD 4.47761
398 1R37 NAD 4.47761
399 5JCM ISD 4.47761
400 5JCM FAD 4.47761
401 2C5A NAD 4.47761
402 2C5A GDC 4.47761
403 2VT3 ATP 4.47761
404 1LCF OXL 4.47761
405 1GR0 NAD 4.63215
406 1Q0S SAH 4.6332
407 3FGZ BEF 4.6875
408 1E6E FAD 4.6875
409 5BXV MGP 4.6875
410 4ZA2 NAD 4.74308
411 5ZZ6 NAD 4.80769
412 5ZZ6 ADP 4.80769
413 3PT9 SAH 4.85075
414 1RJD SAM 4.85075
415 3NDJ SAH 4.85075
416 3NDJ JHZ 4.85075
417 1NW5 SAM 4.85075
418 5N0J FAD 4.85075
419 4YAC NAI 4.85075
420 1GPE FAD 4.85075
421 4HXY NDP 4.85075
422 4OPC PGT 4.85075
423 4OPC FDA 4.85075
424 1ELI PYC 4.85075
425 3S1S SAH 4.85075
426 5WGR FAD 4.85075
427 1BW9 NAD 4.85075
428 1I8T FAD 4.85075
429 1OC2 NAD 4.85075
430 1OC2 TDX 4.85075
431 2QA1 FAD 4.85075
432 5GWT SIN 4.85075
433 5GWT NAD 4.85075
434 2HQM FAD 4.85075
435 3ZNN 4WL 4.85075
436 3ZNN FAD 4.85075
437 5BUK FAD 4.85075
438 1PL6 NAD 4.85075
439 5MBX SP5 4.85075
440 5MBX FAD 4.85075
441 4USR FAD 4.85075
442 1PL6 572 4.85075
443 1LLU NAD 4.85075
444 1LDN NAD 4.85075
445 6DNT NAD 4.85075
446 2DFV NAD 4.85075
447 5WS9 AMP 4.85075
448 1UP7 NAD 4.85075
449 2NPX FAD 4.85075
450 2NPX NAD 4.85075
451 5KKA 6V0 4.85075
452 4MO2 FAD 4.8913
453 4MO2 FDA 4.8913
454 6ER9 NAP 4.91803
455 6ER9 FAD 4.91803
456 1O97 AMP 4.92424
457 1O97 FAD 4.92424
458 3RGG AIR 5.03145
459 5ME4 HP4 5.10949
460 5X62 SAH 5.22388
461 5XNC MTA 5.22388
462 2PX8 SAH 5.22388
463 1V5F FAD 5.22388
464 1V5F TPP 5.22388
465 2IID FAD 5.22388
466 2IID PHE 5.22388
467 5J60 FAD 5.22388
468 2V3V MGD 5.22388
469 5EJ2 NAD 5.22388
470 4J56 FAD 5.22388
471 1P3D UMA 5.22388
472 1P31 EPU 5.22388
473 1SAY PYR 5.22388
474 4XYM COA 5.22388
475 3RHJ NAP 5.22388
476 2BD0 NAP 5.32787
477 5ZW3 SAH 5.33333
478 5AHW CMP 5.44218
479 1SQL GUN 5.47945
480 2Q46 NAP 5.5336
481 3SJ7 NDP 5.55556
482 5YJI SAH 5.59701
483 5YJI 8WO 5.59701
484 2EG5 SAH 5.59701
485 3GRU AMP 5.59701
486 4DMG SAM 5.59701
487 5FEU NAP 5.59701
488 1BC5 SAH 5.59701
489 4AP3 FAD 5.59701
490 4AP3 NAP 5.59701
491 4J1Q NDP 5.59701
492 4B63 NAP 5.59701
493 4B63 FAD 5.59701
494 4B63 ORN 5.59701
495 2C7G FAD 5.59701
496 2C7G ODP 5.59701
497 1NVM NAD 5.59701
498 1RP0 AHZ 5.59701
499 4YRY FAD 5.59701
500 4YRY NAD 5.59701
501 5NA1 FAD 5.59701
502 4ZVV NAD 5.59701
503 4ZVV GN0 5.59701
504 5WQP NAP 5.59701
505 3A28 NAD 5.81395
506 5FFF 5XC 5.83658
507 5FFF NAP 5.83658
508 1FK8 NAD 5.83658
509 1U3U NAD 5.88235
510 1U3U BNF 5.88235
511 5ICE 2H4 5.97015
512 5ICE SAH 5.97015
513 5TS5 FAD 5.97015
514 5HSA FAS 5.97015
515 2JB2 FAD 5.97015
516 2JB2 PHE 5.97015
517 1ORR NAD 5.97015
518 6EL3 NAP 5.97015
519 1TZD ADP 5.97015
520 2RAB NAD 5.97015
521 2RAB FAD 5.97015
522 1COY FAD 5.97015
523 3LAD FAD 5.97015
524 2GV8 FAD 5.97015
525 2GVC FAD 5.97015
526 1VQW FAD 5.97015
527 2VHW NAI 5.97015
528 3NTD FAD 5.97015
529 3NTA FAD 5.97015
530 1G8K MGD 6.01504
531 5T2U NAP 6.04839
532 1Z5U CMP 6.07477
533 3AB1 FAD 6.11111
534 3O7W SAM 6.12245
535 2FKA BEF 6.20155
536 6FC1 MGP 6.21762
537 1GEG NAD 6.25
538 1DJL NAP 6.28019
539 2QX0 PH2 6.28931
540 2OBF SAH 6.34328
541 2OBF F83 6.34328
542 4N49 SAM 6.34328
543 1BDB NAD 6.34328
544 1GZ6 NAI 6.34328
545 2CDU FAD 6.34328
546 4X9M FAD 6.34328
547 3S5W FAD 6.34328
548 3QWI CUE 6.34328
549 3QWI NAP 6.34328
550 2CDU ADP 6.34328
551 5GWX SAR 6.34328
552 5GWX SAM 6.34328
553 1KEW NAD 6.34328
554 4RQU NAD 6.34328
555 2H7C SIA 6.34328
556 2ZXI FAD 6.34328
557 4EMI NAD 6.34328
558 4LHD GLY 6.34328
559 4EMI FAD 6.34328
560 5DM1 5D7 6.36704
561 5DM1 SAH 6.36704
562 2EWM NAD 6.4257
563 2VDV SAM 6.50407
564 2NU5 NAG 6.55738
565 2XYQ SAH 6.55738
566 2GUD MAN 6.55738
567 2GUD BMA 6.55738
568 2HYQ MAN MAN 6.55738
569 5KXE 6Y2 6.58436
570 5ERG SAM 6.71642
571 3ZV6 4HB 6.71642
572 3ZV6 NAD 6.71642
573 5BVA FAD 6.71642
574 1NJR XYL 6.71642
575 4DCM SAM 6.71642
576 4BJZ FAD 6.71642
577 4BJZ P3A 6.71642
578 1G0N NDP 6.71642
579 1G0N PHH 6.71642
580 2Y6Q I7T 6.71642
581 2Y6Q FAD 6.71642
582 2OOR TXP 6.71642
583 3TN7 NJP 6.71642
584 1NM5 NAP 6.71642
585 1NM5 NAD 6.71642
586 5Y77 FAD 6.71642
587 4GLL NAD 6.71642
588 5J7X FAD 6.71642
589 1O5I NAD 6.71642
590 1U4J MAN 6.77966
591 1OFU GDP 6.875
592 3NUG NAD 6.88259
593 1D4O NAP 7.06522
594 4FN4 NAD 7.08661
595 1N2X SAM 7.08955
596 6DEN TP9 7.08955
597 6DEN FAD 7.08955
598 6DEN G8A 7.08955
599 1BXK NAD 7.08955
600 4D7E FAD 7.08955
601 3UOY NAP 7.08955
602 3UOY FAD 7.08955
603 4MOP 2H5 7.08955
604 2FR1 NDP 7.08955
605 1XG5 NAP 7.08955
606 2WET FAD 7.08955
607 3P9C SAH 7.08955
608 1UXG NAD 7.08955
609 1UXG FUM 7.08955
610 2FAV APR 7.22222
611 3G89 SAM 7.22892
612 5O4J PJL 7.29927
613 5O4J 9KH 7.29927
614 5O4J SAH 7.29927
615 3DXY SAM 7.33945
616 5MW4 5JU 7.46269
617 2A14 SAH 7.46269
618 1KYZ SAH 7.46269
619 4XQC NAD 7.46269
620 4XQC 13D 7.46269
621 5ZYN FAD 7.46269
622 3RIY NAD 7.46269
623 3KLJ FAD 7.46269
624 2Z3Y F2N 7.46269
625 6EQS BV8 7.46269
626 3WLE NAD 7.46269
627 5MZI FYK 7.46269
628 5MZI FAD 7.46269
629 2R4J FAD 7.46269
630 2R4J 13P 7.46269
631 2F1K NAP 7.46269
632 2YVF NAD 7.46269
633 2YVF FAD 7.46269
634 1KYZ FER 7.46269
635 3CTY FAD 7.46269
636 2AF6 BRU 7.46269
637 2YVJ FAD 7.46269
638 3I53 SAH 7.83133
639 4A6D SAM 7.83582
640 3X0D SAH 7.83582
641 1D4D FAD 7.83582
642 5MIT FAD 7.83582
643 5MIT NAP 7.83582
644 1RM0 D6P 7.83582
645 1RM0 NAI 7.83582
646 2PT9 2MH 7.83582
647 2PT9 S4M 7.83582
648 2I7C AAT 7.83582
649 2C31 TZD 7.83582
650 2C31 ADP 7.83582
651 6H3O FAD 7.83582
652 4REP FAD 7.83582
653 4YDD MD1 7.83582
654 4YDD MGD 7.83582
655 1ZK7 FAD 7.83582
656 6AIN FAD 7.83582
657 4MIG G3F 7.83582
658 1WVG APR 7.83582
659 1PJS NAD 7.83582
660 1V8B NAD 7.83582
661 5YU3 PRO 7.83582
662 5YU3 NAD 7.83582
663 4RSL FAD 7.86517
664 2PXX SAH 7.90698
665 3EWP APR 7.9096
666 4BLW AMP 7.95848
667 4BLW SAH 7.95848
668 2GAG NAD 8.09524
669 2GAG FAD 8.09524
670 2GAG FOA 8.09524
671 3GU3 SAH 8.09859
672 4CQM NAP 8.19672
673 3TKY SAH 8.20895
674 3A4T SFG 8.20895
675 4JNA FAD 8.20895
676 1FL2 FAD 8.20895
677 1T9D 1MM 8.20895
678 1T9D PYD 8.20895
679 5WKC FAD 8.20895
680 1T9D P25 8.20895
681 1T9D FAD 8.20895
682 4YKG FAD 8.20895
683 4YKG NAD 8.20895
684 4GKV NAD 8.20895
685 1DMR PGD 8.20895
686 3LXD FAD 8.20895
687 3NKS FAD 8.20895
688 1E3I CXF 8.20895
689 4C3Y FAD 8.20895
690 1JNR FAD 8.20895
691 4C3Y ANB 8.20895
692 4M52 FAD 8.20895
693 4M52 M52 8.20895
694 2A8X FAD 8.20895
695 3AY6 NAI 8.20895
696 1WY7 SAH 8.21256
697 6BWL NAD 8.23171
698 5YEC ATP 8.40336
699 4J4H NAI 8.49421
700 4J4H 1J1 8.49421
701 4JK3 NAD 8.49421
702 4YSX FAD 8.51064
703 1YC5 NCA 8.53659
704 4BUZ OAD 8.53659
705 4BUZ NAD 8.53659
706 4BUZ OCZ 8.53659
707 1TV5 FMN 8.57788
708 6GKV SAH 8.58209
709 5E9W SAH 8.58209
710 5KMS FAD 8.58209
711 2O07 SPD 8.58209
712 3AD8 NAD 8.58209
713 2O07 MTA 8.58209
714 3OND NAD 8.58209
715 3OND ADN 8.58209
716 5KMS NAD 8.58209
717 3AD8 PYC 8.58209
718 3AD8 FAD 8.58209
719 3QFA FAD 8.58209
720 4D42 NAP 8.58209
721 4D42 W0I 8.58209
722 5WUW NAP 8.58209
723 2BZ1 TAU 8.67347
724 5X68 FAD 8.69565
725 2EUG URA 8.73362
726 2Q1W NAD 8.95522
727 2E5V FAD 8.95522
728 5TWB FAD 8.95522
729 6FHO FAD 8.95522
730 1P0F NAP 8.95522
731 4MP8 MLI 8.95522
732 4MP8 NAD 8.95522
733 2HMT NAI 9.02778
734 5J6Y GLC 9.04255
735 5J6Y BGC 9.04255
736 3LCC SAH 9.32836
737 4G5H NAP 9.32836
738 4G5H UD7 9.32836
739 1R27 MGD 9.32836
740 4HSU FAD 9.32836
741 4GUT FAD 9.32836
742 4FWE FAD 9.32836
743 4GUS FAD 9.32836
744 2FZW NAD 9.32836
745 5THQ NDP 9.32836
746 3V1U NAD 9.32836
747 4ORM FMN 9.32836
748 4ORM 2V6 9.32836
749 4ORM ORO 9.32836
750 4JN6 OXL 9.32836
751 1QAN SAH 9.42623
752 6GAS FAD 9.66767
753 1E5Q NDP 9.70149
754 3SSO SAH 9.70149
755 3NJ4 AFX 9.70149
756 1Q9I TEO 9.70149
757 1Q9I FAD 9.70149
758 5UAO FAD 9.70149
759 4ZCC FAD 9.70149
760 4ZCC NAI 9.70149
761 3IHG FAD 9.70149
762 4J7U YTZ 9.70149
763 4J7U NAP 9.70149
764 1Z6Z NAP 9.70149
765 3NJ4 NAD 9.70149
766 1XDS SAM 9.89305
767 4NBU NAI 10
768 3R51 MMA 10
769 2Q7V FAD 10.0746
770 2IVF MGD 10.0746
771 3U4C NDP 10.0746
772 3C3Y SAH 10.1266
773 5DLY SAH 10.1504
774 5DLY 5D7 10.1504
775 1S7G APR 10.2767
776 1S7G NAD 10.2767
777 3Q87 SAM 10.4
778 1ZBQ NAD 10.4478
779 3EYA FAD 10.4478
780 1AE1 NAP 10.4478
781 2GMH FAD 10.4478
782 1PR9 NAP 10.6557
783 3D3W NAP 10.6557
784 3GDH SAH 10.7884
785 4X60 3XV 10.8209
786 4X60 SFG 10.8209
787 5FWA J7C 10.8209
788 2IZ1 ATR 10.8209
789 1H0H MGD 10.8209
790 4OM8 NAD 10.8209
791 4MCC 21X 10.9756
792 3WV8 ATP 11.0092
793 4C4A SAH 11.194
794 2ZIF SAM 11.194
795 1RKX NAD 11.194
796 2RGJ FAD 11.194
797 5GSN FAD 11.194
798 5GSN NAP 11.194
799 5GSN MMZ 11.194
800 3JWH SAH 11.5207
801 1KQF MGD 11.5207
802 1G55 SAH 11.5672
803 1XCL SAH 11.5672
804 3CH6 NAP 11.5672
805 3CH6 311 11.5672
806 1P1C SAH 11.5672
807 3VPH OXM 11.5672
808 3VPH NAD 11.5672
809 6HOY TSN 11.5672
810 1NV8 MEQ 11.6197
811 1NV8 SAM 11.6197
812 5N53 8NB 11.7949
813 5OJI ISN 11.9231
814 5OJI NAP 11.9231
815 1YQD NAP 11.9403
816 2DPM SAM 11.9718
817 4CVN ADP 12.4088
818 3EGI ADP 12.6214
819 2PZM UDP 12.6866
820 2PZM NAD 12.6866
821 1XSE NDP 12.6866
822 3O03 NAP 12.6866
823 2VPY MGD 12.8205
824 1I2B NAD 13.0597
825 1I2B USQ 13.0597
826 1I2B UPG 13.0597
827 3OZ2 FAD 13.0597
828 1L1E SAH 13.2404
829 2NXE SAM 13.3858
830 4M73 SAH 13.4328
831 4M73 M72 13.4328
832 2FK8 SAM 13.4328
833 4J36 1HR 13.4328
834 4J36 FAD 13.4328
835 1OBB NAD 13.4328
836 5W7K SAH 13.7821
837 1QZZ SAM 13.806
838 3F8D FAD 13.806
839 5J5Z FAD 13.806
840 3RNM FAD 13.806
841 2F5Z FAD 13.806
842 5EEH SAH 14.0957
843 5EEH P9P 14.0957
844 5M67 NAD 14.1791
845 5M67 3D1 14.1791
846 5M67 ADE 14.1791
847 4II2 ATP 14.4578
848 1TPY SAH 14.9254
849 5MPT SAH 14.9254
850 4TM3 FAD 14.9254
851 1R18 SAH 14.978
852 3FZG SAM 15
853 5LW0 AR6 15.5844
854 2DT5 NAD 15.6398
855 2EFJ SAH 15.6716
856 2WSB NAD 15.748
857 5THY SAH 16.0448
858 5THZ SAH 16.0448
859 3DMH SAM 16.0448
860 3UCL NAP 16.0448
861 3UCL CYH 16.0448
862 3UCL FAD 16.0448
863 3DMH GMP 16.0448
864 5D4V SAH 16.0448
865 2Q1S NAI 16.0448
866 3HVJ 705 16.2896
867 4AZW SAM 16.4179
868 2YX1 SFG 16.4179
869 3VC1 SAH 16.4179
870 3VC1 GST 16.4179
871 3TLJ SAH 17.1642
872 4Y30 49L 17.1642
873 1JG3 ADN 17.1642
874 4Y30 SAH 17.1642
875 1U1I NAD 17.1642
876 1KPG SAH 17.5373
877 2PWY SAH 17.8295
878 4D04 FAD 17.9104
879 4D04 NAP 17.9104
880 1CDO NAD 17.9104
881 5E8J SAH 18.1818
882 4GQB 0XU 18.1818
883 4FZV SAM 18.2836
884 2VVM FAD 18.2836
885 2VVL FAD 18.2836
886 1NNU NAD 18.3333
887 1NNU TCT 18.3333
888 3OFK SAH 18.5185
889 1I1N SAH 18.6567
890 3H5N ATP 18.6567
891 4QTU SAM 18.75
892 4XUC 43G 18.8073
893 4XUC SAM 18.8073
894 5KOK SAH 19.0299
895 5KOK S9T 19.0299
896 5KOK R9T 19.0299
897 4M38 SAH 19.0476
898 1DL5 SAH 19.403
899 6FBZ MGP 19.7531
900 6ARJ BW4 19.7761
901 6ARJ SAH 19.7761
902 3A27 SAM 19.7761
903 5DX0 SFG 19.7761
904 5DWQ SFG 19.7761
905 6DUB SAH 19.8198
906 5FA5 MTA 20
907 1KPH SAH 20.1493
908 4RL4 PPV 20.283
909 3MB5 SAM 20.7843
910 1Z3C SA8 20.8955
911 1EJ0 SAM 22.7778
912 4R6W SAH 22.8682
913 4R6W PC 22.8682
914 5MGZ SAH 23.3051
915 1VE3 SAM 23.348
916 5M58 SAH 23.4783
917 5WP4 SAH 23.5075
918 5WP5 SAH 23.5075
919 2XVM SAH 24.1206
920 5FUB SAH 24.6269
921 4EMJ FAD 25.2336
922 1LSS NAD 26.4286
923 5E1M PRO PRO LYS ARG ILE ALA 26.556
924 5E1M SAH 26.556
925 6D6Y SAH 28.3582
926 1IM8 SAI 29.5082
927 4IWN GEK 30.5677
928 3CBG SAH 32.3276
929 5DX8 SFG 36.8421
930 5DXA SFG 36.8421
931 5DX1 SFG 36.8421
Pocket No.: 2; Query (leader) PDB : 3T7S; Ligand: SAM; Similar sites found with APoc: 28
This union binding pocket(no: 2) in the query (biounit: 3t7s.bio4) has 21 residues
No: Leader PDB Ligand Sequence Similarity
1 6FX2 FUC C4W NAG BMA MAN NAG GAL None
2 2CVQ NDP 1.83486
3 5XFV FMN 1.86567
4 4U7W NDP 2.23881
5 4JCA CIT 2.39521
6 4TVD BGC 2.98507
7 3K1X DBX 3.07692
8 1RYO OXL 3.35821
9 1DTL BEP 3.72671
10 1RJW ETF 3.73134
11 1ZK4 AC0 3.98406
12 2WPB ZZI 4.10448
13 4Q9N NAI 5.22388
14 5NV9 SLB 5.22388
15 4XZ3 COA 5.22388
16 5WQP NCA 5.59701
17 1NVM OXL 5.59701
18 1COY AND 5.97015
19 5ZBC FAD 7.31707
20 3HGM ATP 7.48299
21 4XW2 SIM 8.08081
22 3AY6 BGC 8.20895
23 4PLT NAI 10.0746
24 6HOY AR6 11.5672
25 5XL4 SIA 11.9318
26 3CIF NAD 13.806
27 3CIF G3H 13.806
28 3KIF GDL 16.9811
Pocket No.: 3; Query (leader) PDB : 3T7S; Ligand: SAM; Similar sites found with APoc: 23
This union binding pocket(no: 3) in the query (biounit: 3t7s.bio3) has 21 residues
No: Leader PDB Ligand Sequence Similarity
1 2B9W FAD 2.23881
2 2P9T 3PG 2.61194
3 1GTE IUR 2.98507
4 1GTE FMN 2.98507
5 4X7G 3Y8 3.18725
6 4WBD CIT 4.47761
7 2CI5 HCS 4.47761
8 1EJH M7G 4.73684
9 3WQQ IB3 4.85075
10 3WQQ NDP 4.85075
11 1MXG ACR 5.59701
12 1VM6 NAD 5.59701
13 1JBW ACQ 5.97015
14 3CV2 COA 6.34328
15 1VPE 3PG 6.34328
16 2GUC MAN 6.55738
17 3IID APR 6.63507
18 3GUZ PAF 6.81818
19 2WDQ TEO 7.75194
20 3FG2 FAD 8.41584
21 4PLT OXM 10.0746
22 2Q0L FAD 11.9403
23 5T46 MGP 25.7576
Pocket No.: 4; Query (leader) PDB : 3T7S; Ligand: SAM; Similar sites found with APoc: 8
This union binding pocket(no: 4) in the query (biounit: 3t7s.bio1) has 21 residues
No: Leader PDB Ligand Sequence Similarity
1 6HKE LMR 1.57233
2 4WGF HX2 2.43902
3 5HCF BGC 2.61194
4 3GD8 GOL 2.69058
5 5A1S FLC 3.73134
6 2HYR BGC GLC 6.55738
7 1TLL FMN 7.08955
8 5EIN NAP 11.1111