Receptor
PDB id Resolution Class Description Source Keywords
3U6B 2.12 Å NON-ENZYME: OTHER EF-TU (ESCHERICHIA COLI) IN COMPLEX WITH NVP-LDI028 ESCHERICHIA COLI TRANSLATION FACTOR-ANTIBIOTIC COMPLEX
Ref.: ANTIBACTERIAL OPTIMIZATION OF 4-AMINOTHIAZOLYL ANAL THE NATURAL PRODUCT GE2270 A: IDENTIFICATION OF THE CYCLOALKYLCARBOXYLIC ACIDS. J.MED.CHEM. V. 54 8099 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP A:402;
B:401;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
MG A:401;
B:402;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3U6B 2.12 Å NON-ENZYME: OTHER EF-TU (ESCHERICHIA COLI) IN COMPLEX WITH NVP-LDI028 ESCHERICHIA COLI TRANSLATION FACTOR-ANTIBIOTIC COMPLEX
Ref.: ANTIBACTERIAL OPTIMIZATION OF 4-AMINOTHIAZOLYL ANAL THE NATURAL PRODUCT GE2270 A: IDENTIFICATION OF THE CYCLOALKYLCARBOXYLIC ACIDS. J.MED.CHEM. V. 54 8099 2011
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 3U6B - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 3U6B - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 3U6B - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3U6B; Ligand: GDP; Similar sites found: 521
This union binding pocket(no: 1) in the query (biounit: 3u6b.bio1) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1EK0 GNP 0.0000000007239 0.78639 None
2 1D5C GDP 0.00000000002495 0.83719 1.23457
3 1YTM ATP 0.0000173 0.45069 1.26904
4 2F3R G5P 0.01967 0.4174 1.26904
5 2WKQ GTP 0.000000008881 0.53922 1.50602
6 1V8K ANP 0.00001173 0.54593 1.52284
7 1DJN ADP 0.02522 0.40264 1.52284
8 4FCW ADP 0.00007896 0.50941 1.60772
9 1Z0F GDP 0.000000000005328 0.85509 1.67598
10 2GWH A3P 0.001717 0.45201 1.67785
11 3ZS9 ADP ALF 0.000006136 0.58959 1.69492
12 2WOJ ADP ALF 0.000008077 0.58352 1.69492
13 4M7V RAR 0.03419 0.41629 1.71429
14 4M7V NAP 0.02441 0.41249 1.71429
15 2G77 GDP 0.000000000007728 0.69789 1.77665
16 5HR5 ADP 0.00004613 0.52922 1.77665
17 5LB3 ADP 0.0001243 0.49363 1.77665
18 2XAU ADP 0.000407 0.47778 1.77665
19 2G77 AF3 0.005416 0.42599 1.77665
20 5HR5 FLC 0.01992 0.41712 1.77665
21 1P9B GDP 0.00000239 0.5924 1.80995
22 4ZNL BEF ADP 0.00001406 0.54555 1.82482
23 1NST A3P 0.001396 0.45644 1.84615
24 1TAD ALF 0.0000000003825 0.80936 1.85185
25 1TAD GDP 0.0000000003825 0.80936 1.85185
26 1U0J ADP 0.0005739 0.46208 1.87266
27 5L3W GDP 0.000001416 0.5971 1.96078
28 2F9L GDP 0.0000000001365 0.81633 2.01005
29 5TSH ANP 0.00001982 0.53504 2.03046
30 1XKV ATP 0.00009247 0.50902 2.03046
31 5TSH ADP 0.00007261 0.48247 2.03046
32 1OIV GDP 0.0000000001054 0.82877 2.09424
33 1OIX GDP 0.0000000001436 0.82197 2.09424
34 1G6O ADP 0.00003963 0.47396 2.12121
35 1MH1 GNP 0.000000005933 0.74294 2.15054
36 1G4U GDP 0.000000007747 0.71836 2.17391
37 5MEX PAP 0.002474 0.4463 2.17391
38 5MEX SZZ 0.007104 0.4463 2.17391
39 2B8T THM 0.002279 0.45197 2.24215
40 2VVG ADP 0.0000001216 0.55438 2.28426
41 1K6M AGS 0.00008822 0.52469 2.28426
42 3NHB ADP 0.00001213 0.51315 2.28426
43 2DPY ADP 0.0001163 0.50226 2.28426
44 4A4Z ANP 0.0007005 0.46093 2.28426
45 3DEF GDP 0.000000792 0.61275 2.29008
46 1VHT BA3 0.00009981 0.50741 2.29358
47 5HCN GCP 0.000000001034 0.74479 2.29885
48 4KFU ACP 0.000001847 0.5496 2.35849
49 4R2I ANP 0.001243 0.44067 2.38095
50 2D7C GTP 0.0000000001078 0.82827 2.39521
51 3BER AMP 0.006878 0.40352 2.40964
52 1E2K TMC 0.0001546 0.53656 2.41692
53 3DZD ADP 0.0003179 0.48557 2.44565
54 2ZFI ADP 0.000008369 0.53201 2.45902
55 3ZQ6 ADP ALF 0.000004057 0.59874 2.46914
56 4LPS GDP 0.000000008297 0.7012 2.47934
57 4IXH IMP 0.01284 0.41757 2.49307
58 4P4T GDP 0.00000002803 0.5639 2.5
59 3FVQ ATP 0.0001171 0.51414 2.50696
60 5KSZ GCP 0.00000008312 0.65687 2.53807
61 1IHU ADP 0.0000019 0.60835 2.53807
62 1IHU AF3 0.000001687 0.60835 2.53807
63 4HSE ADP 0.00002478 0.53368 2.53807
64 4IOK XPO 0.0002619 0.50294 2.53807
65 4IOK ADP 0.0003352 0.50294 2.53807
66 5TIV A3P 0.003438 0.46825 2.53807
67 1OYY AGS 0.00302 0.43053 2.53807
68 5BQ5 ADP BEF 0.00008765 0.46399 2.6455
69 1CR1 TTP 0.00003083 0.54294 2.7027
70 1F2U ATP 0.0005053 0.49214 2.7027
71 3TMK T5A 0.0001178 0.52791 2.77778
72 2QTV GNP 0.000000003242 0.7504 2.79188
73 2C9O ADP 0.00003237 0.54189 2.79188
74 1G41 ADP 0.00004095 0.52619 2.79188
75 2VF7 ADP 0.0001015 0.50416 2.79188
76 1P3D ANP 0.009908 0.41826 2.79188
77 1Q19 APC 0.01774 0.40729 2.79188
78 4TMK T5A 0.005353 0.44812 2.8169
79 4BQS K2Q 0.0001315 0.53487 2.84091
80 4BQS ADP 0.0000133 0.52301 2.84091
81 2ZR9 DTP 0.00004557 0.51773 2.86533
82 3QXC ATP 0.00002148 0.56191 2.89256
83 1SVM ATP 0.0001821 0.54092 2.91777
84 2FFQ GSP 0.00000000009806 0.83358 2.92398
85 1R2Q GNP 0.0000000001167 0.8493 2.94118
86 1YZQ GNP 0.00000000005334 0.84703 2.94118
87 3QKT ANP 0.0002577 0.5033 2.94985
88 3MJH GTP 0.00000000004211 0.84896 2.97619
89 1RRC ADP 0.000006098 0.50847 2.99003
90 3Q72 GNP 0.00000000004666 0.79875 3.01205
91 3LOO B4P 0.03897 0.406 3.0137
92 1OE0 TTP 0.001528 0.46768 3.04348
93 1GOT GDP 0.0000000009364 0.77096 3.04569
94 5I0H ADP BEF 0.00006514 0.5268 3.04569
95 4IHQ ADP 0.0001215 0.4941 3.04569
96 4YS0 ADP 0.0007576 0.46949 3.04569
97 5MZN ADP 0.0005949 0.45261 3.04569
98 1GOJ ADP 0.0000001043 0.67964 3.09859
99 2XTZ GSP 0.0000000001246 0.82509 3.10734
100 3ZFD ANP 0.00001244 0.5513 3.1339
101 3VX3 ADP 0.00006966 0.52295 3.22581
102 2FH5 GTP 0.00000000005043 0.83046 3.24324
103 1P72 ADP 0.0003046 0.51147 3.29341
104 1QF5 GDP 0.000007614 0.61772 3.29949
105 4PFO ADP 0.00007353 0.53279 3.29949
106 1QF5 RPL 0.002583 0.5101 3.29949
107 4PJ3 ANP 0.0009803 0.46168 3.29949
108 2B8W ALF 5GP 0.0001596 0.51379 3.35366
109 1JJV ATP 0.000009605 0.52095 3.39806
110 3FYH ADP 0.0001145 0.52107 3.41615
111 5X40 ACP 0.0002302 0.50378 3.42466
112 3B7G ANP 0.000556 0.46855 3.47826
113 3UIE ANP 0.00001676 0.54502 3.5
114 4GOX A3P 0.00005245 0.53603 3.51438
115 1W0J ADP 0.000002573 0.58776 3.5533
116 1W0J ADP BEF 0.00009681 0.51588 3.5533
117 2ZPA ADP 0.000134 0.50891 3.5533
118 3TBK ANP 0.0007226 0.44981 3.5533
119 2CK3 ANP 0.0001167 0.42851 3.5533
120 2CK3 ADP 0.0001408 0.40242 3.5533
121 2ZE7 AMP 0.003371 0.4486 3.55731
122 2ZE7 DST 0.003621 0.4486 3.55731
123 1KAO GDP 0.0000000001117 0.80519 3.59281
124 3H86 AP5 0.0002466 0.51916 3.64583
125 4XTR ADP 0.000003905 0.58479 3.68664
126 4XTR ATP 0.000005599 0.58479 3.68664
127 4XVU ATP 0.000007529 0.57834 3.68664
128 1S3G AP5 0.0004049 0.5144 3.68664
129 2Z5F A3P 0.0009915 0.46803 3.69128
130 5UQW GDP 0.00000000006745 0.83521 3.7037
131 4GBM A3P 0.0003265 0.49617 3.71517
132 2ZPT A3P 0.01314 0.44525 3.72881
133 4WZ6 ATP 0.000008042 0.52006 3.7931
134 1TU3 GNP 0.00000000003373 0.85384 3.79747
135 1Z06 GNP 0.0000000000362 0.84884 3.80711
136 2BCG GDP 0.00000000005982 0.82275 3.80711
137 2BIF ANP 0.0001684 0.52634 3.80711
138 2BIF SIN 0.0002815 0.52634 3.80711
139 1R6B ADP 0.00005182 0.51823 3.80711
140 3GDN FAD 0.04855 0.40712 3.80711
141 1JJ7 ADP 0.000001146 0.51758 3.84615
142 1FNN ADP 0.0001665 0.42594 3.85604
143 1VKJ A3P 0.00276 0.44592 3.85965
144 1MR3 G3D 0.00000000001645 0.83149 3.8674
145 5M04 GDP 0.000000000002804 0.85674 3.88889
146 3ZIA ADP 0.000005765 0.57064 3.95683
147 3ZIA ATP 0.000005178 0.56645 3.95683
148 2QG6 NMN 0.000132 0.52363 4.0201
149 2FAH GDP 0.00001187 0.55532 4.06091
150 3DC4 ADP 0.00001647 0.52148 4.06091
151 2AWN ADP 0.000000863 0.50209 4.06091
152 2FSH ANP 0.001431 0.44323 4.06091
153 1QHG ATP 0.01035 0.41158 4.06091
154 5WRI A3P 0.000697 0.47768 4.0625
155 4AG5 ADP 0.00001816 0.54825 4.08163
156 2Q2Y ADP 0.0000969 0.54731 4.08719
157 2Q2Y MKR 0.0001048 0.54419 4.08719
158 3QF7 ANP 0.0001584 0.50531 4.10959
159 1ION ADP 0.000009086 0.55792 4.11523
160 4ITM ATP 0.02843 0.40142 4.12698
161 3BOS CDP 0.000007575 0.55502 4.13223
162 3Q85 GNP 0.000000000001215 0.8802 4.14201
163 1ZUI SKM 0.0001656 0.52963 4.16667
164 2GDJ ANP 0.00007879 0.50635 4.16667
165 1DMH LIO 0.04778 0.40583 4.18006
166 4HDO GNP 0.0000000005863 0.79408 4.19162
167 1O3Y GTP 0.00000000006098 0.83389 4.21687
168 1J2J GTP 0.0000000003501 0.58127 4.21687
169 1G3Q ADP 0.000003114 0.5771 4.21941
170 2J0V GDP 0.00000000101 0.74529 4.24528
171 3QBT GNP 0.000000000125 0.56544 4.28571
172 5WRJ A3P 0.0006354 0.48353 4.29043
173 5EP2 AZU 0.02002 0.40297 4.29688
174 4ZG4 VO4 ADP 0.00007825 0.52731 4.31472
175 4X8O AP5 0.0006146 0.51037 4.31472
176 1VM6 NAD 0.02858 0.40268 4.31472
177 4KOT CE3 0.04605 0.40402 4.32099
178 3RWO GDP 0.00000000009763 0.83046 4.32432
179 5L3V GDP 0.0000003429 0.627 4.34783
180 5L3S GNP 0.0000004593 0.64192 4.36242
181 2CHG ANP 0.00003631 0.53434 4.42478
182 1RYH GNP 0.0000000008715 0.75294 4.4335
183 4PX9 ADP 0.0001483 0.48999 4.45205
184 2GCN GDP 0.000000006021 0.73059 4.47761
185 2GCO GNP 0.000000005253 0.72302 4.47761
186 4U00 ADP 0.000004125 0.49801 4.5082
187 5HGZ ACO 0.01394 0.41726 4.52675
188 1XMV ADP 0.00001806 0.5403 4.56853
189 1OS1 PYR 0.0001737 0.52094 4.56853
190 1OS1 ATP 0.0001611 0.52094 4.56853
191 4NON GDP 0.0000000009423 0.52529 4.61538
192 4KBF AMP 0.002378 0.43274 4.65753
193 4FRZ ADP 0.000002356 0.54368 4.66321
194 1Q20 A3P 0.00299 0.46131 4.68227
195 1Q20 PLO 0.00299 0.46131 4.68227
196 1Z08 GNP 0.0000000004701 0.78937 4.70588
197 1J99 AND 0.004604 0.45154 4.77816
198 2A5F GTP 0.00000000006742 0.83522 4.82234
199 1NY5 ADP 0.0001613 0.50251 4.82234
200 2V3V MGD 0.03636 0.43099 4.82234
201 1VG8 GNP 0.00000000007801 0.83863 4.83092
202 1VG0 GDP 0.00000000003274 0.82687 4.83092
203 3COB ADP 0.0000004023 0.55641 4.87805
204 2JAQ DCP 0.001996 0.45669 4.87805
205 1DAK DPU 0.0001222 0.54448 4.91071
206 1DAK ADP 0.002851 0.50093 4.91071
207 3JVH HHV 0.01989 0.4183 4.91803
208 2IYL GDP 0.0000007676 0.6026 4.92958
209 1KY3 GDP 0.0000000001839 0.79026 4.94506
210 2W58 ADP 0.000003484 0.50044 4.9505
211 1RE0 GDP 0.000000000002424 0.85974 4.97738
212 4Q1A 2XZ 0.0002144 0.58629 5
213 4Q1A UDP 0.0002144 0.58629 5
214 4LJ9 ACP 0.0001674 0.49068 5.01475
215 2ZEJ GDP 0.0000000005444 0.79571 5.07614
216 4M9Q GNP 0.000000000005628 0.64678 5.07614
217 1W5T ANP 0.0001867 0.50407 5.07614
218 1W5T ADP 0.0003928 0.48351 5.07614
219 3FB4 AP5 0.0003272 0.51931 5.09259
220 4TTQ ATP 0.00002778 0.52802 5.11628
221 3KJI ADP 0.00001002 0.55891 5.11811
222 1KO8 6PG 0.0002262 0.49767 5.14286
223 1H65 GDP 0.000002223 0.60236 5.18518
224 2O0J ADP 0.008211 0.40167 5.19481
225 2D2F ADP 0.0001102 0.43054 5.2
226 4R3L COA 0.0409 0.40773 5.20231
227 5KSP GDP 0.0000000138 0.69055 5.26316
228 5KUT GDP 0.000000001774 0.7335 5.29101
229 1KUV CA5 0.01749 0.42008 5.31401
230 2NCD ADP 0.000002577 0.59109 5.32995
231 4IDN GNP 0.0000541 0.53313 5.32995
232 4R43 GDP 0.00001518 0.52261 5.32995
233 3BD9 A3P 0.005863 0.41918 5.35714
234 1IN4 ADP 0.00003837 0.53574 5.38922
235 1VG1 GDP 0.000000000004465 0.85879 5.40541
236 1VG9 GDP 0.00000000002788 0.82044 5.40541
237 1UKZ ADP 0.0004051 0.50651 5.41872
238 1CJW COT 0.0143 0.42087 5.42169
239 1T5C ADP 0.00000019 0.54668 5.44413
240 1XP8 AGS 0.00004501 0.51458 5.46448
241 4MKG AP5 0.0002195 0.5285 5.52995
242 1L2T ATP 0.0001234 0.51942 5.53191
243 3T1O GDP 0.00000000006647 0.80718 5.55556
244 1UJ2 C5P 0.00003506 0.55109 5.55556
245 1UJ2 ADP 0.00003675 0.55005 5.55556
246 1WF3 GNP 0.0000000001193 0.82924 5.58376
247 1SVK ALF GDP 0.0000000004953 0.80636 5.58376
248 5KDO GDP 0.0000000008531 0.76942 5.58376
249 1JWY GDP 0.00000001779 0.69328 5.58376
250 1GP2 GDP 0.000000000794 0.57623 5.58376
251 1JWY ADP 0.00002682 0.53202 5.58376
252 3BFX A3P 0.0003833 0.48634 5.58376
253 1XTQ GDP 0.00000000006717 0.83178 5.64972
254 3REF GDP 0.000000008948 0.722 5.6701
255 1YRB GDP 0.00000000001169 0.84871 5.72519
256 2HF9 GSP 0.00000002093 0.58275 5.75221
257 2RGX AP5 0.000579 0.50849 5.82524
258 2BEK ATP 0.000213 0.40739 5.83658
259 2IXE ATP 0.00009364 0.52123 5.83756
260 1G3M PCQ 0.003151 0.46607 5.83756
261 1G3M A3P 0.003151 0.46607 5.83756
262 3MGB PAP 0.003722 0.43946 5.83756
263 5XCO GDP 0.00000000004103 0.82209 5.84795
264 1IWE IMP 0.00002115 0.6274 5.9081
265 2BME GNP 0.0000000001591 0.81972 5.91398
266 1YZN GNP 0.0000000002016 0.81766 5.94595
267 1BO4 COA 0.00357 0.42705 5.95238
268 3FMI KAP 0.01716 0.40801 5.9761
269 2QQ0 ANP 0.00008492 0.54023 5.97826
270 2QQ0 THM 0.00007327 0.54023 5.97826
271 2QQ0 TMP 0.00009333 0.53811 5.97826
272 4MKF AP5 0.00026 0.52582 5.99078
273 1BH2 GSP 0.000000002342 0.76901 6.03175
274 3FWY ADP 0.0000004005 0.63052 6.05096
275 1TQ4 GDP 0.000000000756 0.59669 6.05327
276 4OI4 ATP 0.00006758 0.5305 6.08696
277 5I34 GDP 0.000001248 0.59623 6.09137
278 4WZA ADP 0.00003776 0.58917 6.09137
279 4WZA ACP 0.00003776 0.58917 6.09137
280 3RC3 ANP 0.002601 0.4309 6.09137
281 3DKP ADP 0.0002586 0.48164 6.12245
282 3IUY AMP 0.005346 0.41864 6.14035
283 4U5X GNP 0.000000004962 0.72792 6.17978
284 1M2O GNP 0.000000001198 0.7753 6.31579
285 1FP6 ADP 0.000003454 0.58151 6.34518
286 1X6V ADP 0.00004193 0.55092 6.34518
287 1Z6T ADP 0.00007113 0.44275 6.34518
288 4IEE AGS 0.002112 0.43519 6.34518
289 2PL3 ADP 0.0003373 0.47305 6.35593
290 4K81 GTP 0.0000000005457 0.79861 6.43275
291 4QM7 GTP 0.00005349 0.5144 6.43275
292 3EFS BTN 0.02073 0.40047 6.43777
293 4V0K GDP 0.0000000001042 0.82568 6.50888
294 1GXU 2HP 0.001672 0.42364 6.59341
295 2VOS ADP 0.02384 0.40081 6.59898
296 1CLU DBG 0.0000000008131 0.82028 6.62651
297 3KUD GDP 0.0000000001088 0.81387 6.62651
298 1NVU GTP 0.0000000003033 0.80863 6.62651
299 1NVV GNP 0.000000000318 0.80759 6.62651
300 3DDC GNP 0.000000000321 0.80738 6.62651
301 1WQ1 GDP 0.0000000002097 0.80696 6.62651
302 3H4S ADP 0.000000591 0.54897 6.66667
303 1JI0 ATP 0.00002485 0.53498 6.66667
304 4WOP CTP 0.0004474 0.48521 6.66667
305 2OG2 MLI 0.00001586 0.42165 6.68524
306 2VB6 ADP BEF 0.0000933 0.52347 6.71141
307 2C5L GTP 0.000000000122 0.82875 6.83761
308 2Y65 ADP 0.0000002146 0.56679 6.84932
309 3AB3 GDP 0.00000000008828 0.81838 6.85279
310 3CX8 GSP 0.000000000315 0.81368 6.85279
311 1RJ9 GCP 0.000002139 0.63953 6.85279
312 1F9V ADP 0.000003287 0.5382 6.85279
313 2C04 GCP 0.00001029 0.48751 6.85279
314 1S9D GDP 0.000000000006207 0.77674 6.89655
315 5O2T GSP 0.0000000001542 0.82358 6.95187
316 2GJ8 ALF GDP 0.000000000005775 0.58636 6.97674
317 2XT3 ADP 0.0000006408 0.5485 6.97674
318 1OXV ANP 0.00003608 0.51914 7.08215
319 2RCN GDP 0.00000000002706 0.8157 7.1066
320 3P4X ADP 0.00005891 0.50903 7.1066
321 4QOS ADP 0.0001195 0.45648 7.1066
322 5BYK A3P 0.004899 0.45592 7.1066
323 5BYK OAQ 0.004899 0.45592 7.1066
324 3WQT ANP 0.01672 0.41019 7.1066
325 1FZQ GDP 0.0000000000006639 0.89276 7.18232
326 4LC1 GDP 0.00000000003318 0.77359 7.4184
327 4D81 ADP 0.0000327 0.53382 7.42049
328 3RLF ANP 0.00009369 0.52338 7.43243
329 1ZJ6 G3D 0.000000000001514 0.88143 7.48663
330 2D7D ADP 0.001317 0.4478 7.5
331 5IRC GDP 0.00000003389 0.67578 7.52688
332 2W2X GSP 0.000000002224 0.74875 7.56757
333 3MD0 GDP 0.000000000006147 0.84055 7.60563
334 1KMQ GNP 0.00000001255 0.71778 7.6087
335 3E70 GDP 0.0000006244 0.61074 7.62195
336 3NC9 TR3 0.03766 0.40966 7.66773
337 1YVD GNP 0.0000000002131 0.81329 7.69231
338 1PVN MZP 0.03901 0.40975 7.71277
339 2DPM SAM 0.02351 0.40269 7.74648
340 2HV8 GTP 0.0000000001993 0.81476 7.8125
341 2IS6 ADP 0.00006529 0.51025 7.86802
342 3TK1 GDP 0.000000000006376 0.81356 7.87879
343 1TX4 ALF GDP 0.00000002047 0.53128 7.9096
344 4DSU GDP 0.0000000001248 0.82825 7.93651
345 3B9Q MLI 0.00001152 0.56468 7.94702
346 1BG2 ADP 0.00000005448 0.56684 8
347 1B0U ATP 0.0001576 0.50045 8.01527
348 1AQU A3P 0.0009567 0.46451 8.08081
349 1YQT ADP 0.00001869 0.50509 8.12183
350 1FQK GDP 0.0000000009031 0.77514 8.16327
351 5L3R GCP 0.0000004796 0.64097 8.19113
352 1GWN GTP 0.000000004567 0.73322 8.29268
353 1DS6 GDP 0.0000000008082 0.7451 8.33333
354 1I4D GDP 0.000000001875 0.72259 8.33333
355 1E96 GTP 0.00000001243 0.72384 8.37438
356 3M1I GTP 0.0000000004868 0.79818 8.37696
357 2KIN ADP 0.00000009309 0.55834 8.40336
358 4C4P GNP 0.00000000009653 0.83393 8.41121
359 1PUJ GNP 0.000000000008804 0.85473 8.51064
360 4HI0 GDP 0.00000001172 0.56582 8.54271
361 3SBD GNP 0.00000001219 0.72427 8.55615
362 2OFW ADX 0.00005685 0.55823 8.65385
363 1Z0K GTP 0.0000000001016 0.82276 8.72093
364 1T8U A3P 0.002055 0.45229 8.82353
365 1T8U UAP SGN IDS SGN 0.006612 0.45006 8.82353
366 3A4M ADP 0.000003216 0.55417 8.84615
367 4DCT GDP 0.00000000000287 0.86804 8.88325
368 1S8F GDP 0.0000000001054 0.83509 8.88325
369 2GMV UN8 0.001713 0.46674 8.88325
370 2GMV PEP 0.002393 0.46227 8.88325
371 1NHX FTB 0.004777 0.46157 8.88325
372 1NHX PEP 0.004687 0.46105 8.88325
373 1YZG GDP 0.000000000001555 0.88088 8.93855
374 2XTN GTP 0.000001014 0.62205 8.97436
375 2FJU GSP 0.000000006662 0.72507 8.98876
376 3B5J 12D 0.00004703 0.50203 9.0535
377 1R4A GNP 0.00000000004246 0.84535 9.09091
378 1LVG ADP 0.0000005062 0.59093 9.09091
379 2V7Q ATP 0.000003038 0.58101 9.09091
380 1HE1 GDP 0.000000005119 0.57222 9.09091
381 2V7Q ADP 0.00007611 0.50707 9.09091
382 4P32 ADP 0.0001493 0.51111 9.23695
383 1M7B GTP 0.000000002505 0.58173 9.23913
384 4NE2 ADP 0.00003159 0.56575 9.28144
385 4NE2 SH2 0.00003613 0.56575 9.28144
386 2GK6 ADP 0.001672 0.43247 9.39086
387 2QEN ADP 0.000006479 0.57112 9.42857
388 3IIJ ADP 0.000006584 0.55794 9.44444
389 2PEZ GGZ 0.00002785 0.56534 9.49721
390 2PEZ DAT 0.00002785 0.56534 9.49721
391 3BFV ADP 0.000003058 0.57388 9.5941
392 1B7T ADP 0.00005265 0.52089 9.61539
393 1KK8 BEF ADP 0.00004912 0.52788 9.74026
394 4BFW ZVW 0.0002429 0.52617 9.74843
395 1OFH ADP 0.00005231 0.52103 9.77011
396 4DID GDP 0.000000003991 0.71652 9.84456
397 3KTA AP5 0.00006201 0.52025 9.89011
398 1NJF AGS 0.00001742 0.55771 10
399 1NJF ADP 0.0000182 0.55176 10
400 4BAS GNP 0.0000000005878 0.78106 10.0503
401 1SQ5 ADP 0.000004689 0.56853 10.0649
402 5CK5 GDP 0.00000000104 0.73473 10.1266
403 1NF3 GNP 0.0000000165 0.71762 10.2564
404 1D2N ANP 0.000643 0.47738 10.2941
405 1QF9 ALF 0.0004917 0.50619 10.3093
406 1QF9 ADP 0.0004917 0.50619 10.3093
407 1QF9 C5P 0.0004917 0.50619 10.3093
408 5HPY GDP 0.000000003966 0.72901 10.3448
409 1ZIN AP5 0.0002742 0.52338 10.4061
410 3GJ5 GDP 0.00000000002372 0.82382 10.4072
411 3GJ3 GDP 0.0000000000186 0.82349 10.4072
412 3GJ4 GDP 0.00000000003215 0.81212 10.4072
413 3GJ0 GDP 0.00000000002493 0.7804 10.4072
414 3GJ8 GDP 0.00000000001946 0.7563 10.4072
415 2CJW GDP 0.00000000000756 0.8422 10.4167
416 1A4R GDP 0.000000002334 0.74411 10.4712
417 1A4R GNH 0.000000002689 0.73731 10.4712
418 2NGR GDP 0.000000001977 0.73123 10.4712
419 1GRN GDP 0.000000005347 0.72264 10.4712
420 4ITR GDP 0.00000001261 0.70789 10.4712
421 2UZI GTP 0.0000000001558 0.82018 10.5769
422 5BXQ GDP 0.00000000002 0.8274 10.6481
423 1IBR GNP 0.0000000007187 0.78958 10.6481
424 2A9K GDP 0.00000000008848 0.81017 10.6952
425 4XTX 590 0.03483 0.40322 10.7407
426 1Z4O GL1 0.02617 0.40032 10.8597
427 4HUT ATP 0.02205 0.4124 10.9948
428 4H6U ACO 0.02443 0.40027 11
429 5N69 ADP 0.00003793 0.53067 11.0553
430 4H1V GNP 0.0000005424 0.53598 11.1111
431 5GJC ATP 0.00005962 0.51214 11.1675
432 3GJ7 GDP 0.00000000003115 0.81278 11.2245
433 5H56 TYD 0.00007753 0.53897 11.2821
434 5H56 ADP 0.00007753 0.53897 11.2821
435 1ZC3 GNP 0.0000000002425 0.81358 11.4286
436 2QZ4 ADP 0.00002473 0.53682 11.4504
437 3T12 GDP ALF 0.0000000001214 0.6081 11.7647
438 1M7G AV2 0.0000009056 0.59513 11.8483
439 1M7G ADX 0.000006838 0.59513 11.8483
440 1M7G ADP 0.00001593 0.57247 11.8483
441 1U8Z GDP 0.0000000001545 0.58645 11.9048
442 1OW3 GDP 0.000000005256 0.72301 11.9171
443 1QHH ATP 0.0128 0.40276 11.976
444 2A5J GDP 0.00000000001814 0.7301 12.0419
445 2CE7 ADP 0.00002409 0.53737 12.1827
446 2WIC GNP 0.0000000002016 0.71428 12.3596
447 4D0N GDP 0.000000001285 0.73546 12.4324
448 1AZT GSP 0.0000000001626 0.82841 12.6904
449 1CS4 GSP 0.0000000003879 0.53836 12.6904
450 3ZL8 ADP 0.01192 0.41425 12.6904
451 1G6H ADP 0.000002883 0.50332 12.8405
452 4HAT GNP 0.0000000005244 0.79949 12.8571
453 1WA5 GTP 0.0000000009176 0.79519 13.0682
454 1Z2A GDP 0.0000000002656 0.58424 13.0952
455 1Z0A GDP 0.000000000012 0.84327 13.2184
456 1W7J ADP BEF 0.00005077 0.44812 13.245
457 2ORV 4TA 0.00193 0.46089 13.2479
458 1SVI GDP 0.00000000006713 0.79125 13.3333
459 4QRH 0O2 0.003747 0.43931 13.3333
460 2HT6 GDP 0.000000000002115 0.86256 13.4518
461 4NCN GTP 0.00000000002458 0.85369 13.4518
462 3T5G GDP 0.00000000002167 0.83081 13.8158
463 2VBQ BSJ 0.01355 0.42931 13.9394
464 5TB5 GDP 0.00000000002339 0.8292 14
465 5TAR GDP 0.00000000002941 0.69747 14.1892
466 1XX6 ADP 0.0002481 0.48251 14.6597
467 5UFQ GNP 0.00000000008266 0.83412 14.7541
468 3RAB GNP 0.000000000033 0.85432 14.7929
469 1G16 GDP 0.00000000164 0.75879 15.2941
470 5UWP GNP 0.0000000005754 0.79743 15.3846
471 5UWU GNP 0.0000000005292 0.79634 15.3846
472 5UWR GNP 0.0000000005467 0.79562 15.3846
473 5UWI GNP 0.0000000005606 0.79506 15.3846
474 5UWT GNP 0.0000000006123 0.79312 15.3846
475 5UWH GNP 0.0000000006162 0.79297 15.3846
476 5UWW GNP 0.0000000006223 0.79276 15.3846
477 5UWO GNP 0.0000000006368 0.79225 15.3846
478 5UWS GNP 0.0000000007513 0.79151 15.3846
479 5DI9 GNP 0.0000000007749 0.79083 15.3846
480 5UWQ GNP 0.0000000004364 0.54148 15.3846
481 5UWJ GNP 0.0000000005556 0.53928 15.3846
482 1G7S GDP 0.00000000000007772 0.85423 15.4822
483 1DAR GDP 0.000000000005251 0.84978 15.4822
484 3EC1 GDP 0.00000000001511 0.83327 15.4822
485 2ODE ALF GDP 0.0000000004288 0.80682 15.6028
486 4YMU ATP 0.00007074 0.50526 15.8333
487 1W4R TTP 0.0003537 0.50176 15.8974
488 4B47 GDP 0.00000000000009437 0.92669 15.978
489 4KVX ACO 0.02606 0.40475 16.0256
490 1F6B GDP 0.00000000003821 0.81384 16.1616
491 2WHX ADP 0.00001646 0.50691 16.2437
492 2JLR ANP 0.0001258 0.50523 16.2437
493 1UPT GTP 0.0000000002439 0.80014 16.6667
494 2OM2 GDP 0.0000000004158 0.61241 16.6667
495 3A1S GDP 0.00000006013 0.65973 17.0543
496 1CXZ GSP 0.000000007488 0.72586 17.4419
497 3W5J GDP 0.000000008909 0.62644 17.5127
498 1KSH GDP 0.000000000003352 0.88896 18.2796
499 1NRJ GTP 0.000000007837 0.72157 18.3486
500 3BC1 GNP 0.0000000001338 0.82353 18.4615
501 1NN5 ANP 0.00004311 0.55382 18.6047
502 4CVN ADP 0.000006524 0.56333 18.8482
503 2ZFZ ARG 0.04036 0.41469 18.9873
504 1MKY GDP 0.0000000000002105 0.91663 19.5431
505 1ZD9 GDP 0.000000000186 0.63402 19.6809
506 4R98 GNH 0.000000001378 0.73402 19.9262
507 1GUA GNP 0.0000000004587 0.53831 21.5569
508 1LFD GNP 0.0000000002129 0.81331 21.8391
509 1Z0J GTP 0.0000000001795 0.82022 22.0339
510 1X1R GDP 0.0000000004396 0.80044 23.5955
511 2WJG GDP 0.00000000001063 0.79736 26.0638
512 3PQC GDP 0.000000002329 0.73222 26.1538
513 3CH5 GDP 0.00000000002124 0.82614 28.8462
514 2WJH GDP 0.00000000004239 0.81167 29.5181
515 2WJH FLC 0.0000001147 0.65008 29.5181
516 5FG3 GDP 0.0000000000002225 0.90899 29.6954
517 1FQJ GDP 0.0000000003714 0.58379 30.9524
518 5DIF GNP 0.000000000527 0.79643 31.5789
519 4RD0 GDP 0.0000000000001503 0.96047 35.7868
520 2QN6 GDP 0.00000000000003175 0.94914 36.0406
521 1KK1 GNP 0.00000000000005218 0.93892 42.3858
522 1Y3A GDP 0.0000000007543 0.77906 50
Pocket No.: 2; Query (leader) PDB : 3U6B; Ligand: GDP; Similar sites found: 8
This union binding pocket(no: 2) in the query (biounit: 3u6b.bio2) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1BXK NAD 0.03576 0.40144 2.53521
2 1GQY ACP 0.01622 0.40198 2.79188
3 1ZRH A3P 0.01777 0.40557 3.64964
4 2YY7 NAD 0.04035 0.40099 4.48718
5 1S7N COA 0.02073 0.40221 7.69231
6 1V3S ATP 0.02253 0.40039 8.62069
7 1W78 ADP 0.02654 0.40001 9.39086
8 2JDC CAO 0.02911 0.40488 10.274
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