Receptor
PDB id Resolution Class Description Source Keywords
3U6K 2.45 Å NON-ENZYME: OTHER EF-TU (ESCHERICHIA COLI) IN COMPLEX WITH NVP-LDK733 ESCHERICHIA COLI TRANSLATION FACTOR-ANTIBIOTIC COMPLEX
Ref.: ANTIBACTERIAL OPTIMIZATION OF 4-AMINOTHIAZOLYL ANAL THE NATURAL PRODUCT GE2270 A: IDENTIFICATION OF THE CYCLOALKYLCARBOXYLIC ACIDS. J.MED.CHEM. V. 54 8099 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP A:500;
B:500;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
MG A:394;
B:394;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3U6K 2.45 Å NON-ENZYME: OTHER EF-TU (ESCHERICHIA COLI) IN COMPLEX WITH NVP-LDK733 ESCHERICHIA COLI TRANSLATION FACTOR-ANTIBIOTIC COMPLEX
Ref.: ANTIBACTERIAL OPTIMIZATION OF 4-AMINOTHIAZOLYL ANAL THE NATURAL PRODUCT GE2270 A: IDENTIFICATION OF THE CYCLOALKYLCARBOXYLIC ACIDS. J.MED.CHEM. V. 54 8099 2011
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 3U6K - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 3U6K - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 3U6K - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3U6K; Ligand: GDP; Similar sites found: 474
This union binding pocket(no: 1) in the query (biounit: 3u6k.bio2) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1EK0 GNP 0.00000000412 0.7358 None
2 1D5C GDP 0.0000000002113 0.77765 1.23457
3 1YTM ATP 0.00003875 0.4482 1.26904
4 2F3R G5P 0.03143 0.40297 1.26904
5 2WKQ GTP 0.00000002034 0.54101 1.50602
6 1V8K ANP 0.00002733 0.52079 1.52284
7 1ZUA TOL 0.02817 0.42388 1.57729
8 1ZUA NAP 0.02817 0.42388 1.57729
9 4FCW ADP 0.00013 0.49226 1.60772
10 1Z0F GDP 0.00000000005947 0.78995 1.67598
11 2GWH A3P 0.004463 0.42679 1.67785
12 3ZS9 ADP ALF 0.00001966 0.42183 1.69492
13 2WOJ ADP ALF 0.00002456 0.41965 1.69492
14 2G77 GDP 0.00000000004716 0.68925 1.77665
15 5HR5 ADP 0.0001066 0.50451 1.77665
16 5LB3 ADP 0.0001361 0.49498 1.77665
17 2XAU ADP 0.0007946 0.45793 1.77665
18 2G77 AF3 0.0119 0.4106 1.77665
19 1P9B GDP 0.000007332 0.56019 1.80995
20 4ZNL BEF ADP 0.00003516 0.50152 1.82482
21 1NST A3P 0.001174 0.4546 1.84615
22 1TAD GDP 0.00000000505 0.73967 1.85185
23 1TAD ALF 0.00000000505 0.51322 1.85185
24 1U0J ADP 0.0006201 0.45008 1.87266
25 5L3W GDP 0.000002358 0.57746 1.96078
26 2F9L GDP 0.0000000003354 0.78303 2.01005
27 5TSH ANP 0.00005383 0.50706 2.03046
28 1XKV ATP 0.0001208 0.49663 2.03046
29 5TSH ADP 0.00006686 0.47127 2.03046
30 1OIV GDP 0.0000000004253 0.78451 2.09424
31 1OIX GDP 0.0000000005518 0.77893 2.09424
32 1G6O ADP 0.0001247 0.46498 2.12121
33 1MH1 GNP 0.00000001759 0.51053 2.15054
34 1G4U GDP 0.0000000188 0.68781 2.17391
35 5MEX SZZ 0.008657 0.43731 2.17391
36 5MEX PAP 0.003377 0.43465 2.17391
37 2B8T THM 0.004543 0.43218 2.24215
38 3NHB ADP 0.00002171 0.54787 2.28426
39 2VVG ADP 0.0000001886 0.53047 2.28426
40 2DPY ADP 0.00007974 0.51357 2.28426
41 1K6M AGS 0.0001814 0.50243 2.28426
42 4A4Z ANP 0.002559 0.42887 2.28426
43 3DEF GDP 0.000001814 0.58613 2.29008
44 1VHT BA3 0.0004181 0.47112 2.29358
45 5HCN GCP 0.000000005735 0.67113 2.29885
46 4KFU ACP 0.000003275 0.52387 2.35849
47 4R2I ANP 0.001419 0.45206 2.38095
48 2D7C GTP 0.0000000004589 0.78288 2.39521
49 3BER AMP 0.003895 0.42036 2.40964
50 3DZD ADP 0.000995 0.45574 2.44565
51 2ZFI ADP 0.00001991 0.5272 2.45902
52 3ZQ6 ADP ALF 0.0000155 0.56125 2.46914
53 4LPS GDP 0.00000002074 0.67056 2.47934
54 4P4T GDP 0.00000006536 0.56379 2.5
55 3FVQ ATP 0.0005249 0.4758 2.50696
56 5KSZ GCP 0.0000002112 0.58591 2.53807
57 1IHU AF3 0.000005914 0.57275 2.53807
58 1IHU ADP 0.000006639 0.57275 2.53807
59 4HSE ADP 0.00008385 0.5012 2.53807
60 4IOK ADP 0.0006853 0.48126 2.53807
61 4IOK XPO 0.0005372 0.48126 2.53807
62 1OYY AGS 0.008316 0.40496 2.53807
63 5BQ5 ADP BEF 0.0001679 0.46177 2.6455
64 1CR1 TTP 0.00009175 0.51249 2.7027
65 1F2U ATP 0.001336 0.4652 2.7027
66 3TMK T5A 0.0003586 0.49694 2.77778
67 2QTV GNP 0.00000003668 0.68612 2.79188
68 1G41 ADP 0.00008762 0.50322 2.79188
69 2VF7 ADP 0.0002038 0.48308 2.79188
70 2C9O ADP 0.0001036 0.43218 2.79188
71 1Q19 APC 0.01408 0.40815 2.79188
72 4TMK T5A 0.01347 0.42298 2.8169
73 4BQS ADP 0.00002817 0.52018 2.84091
74 2ZR9 DTP 0.000093 0.496 2.86533
75 3QXC ATP 0.00006224 0.53129 2.89256
76 2FFQ GSP 0.00000000088 0.77193 2.92398
77 1R2Q GNP 0.0000000004349 0.80592 2.94118
78 1YZQ GNP 0.000000000399 0.78897 2.94118
79 3QKT ANP 0.0007661 0.47367 2.94985
80 3MJH GTP 0.0000000001594 0.57633 2.97619
81 1RRC ADP 0.00001277 0.48192 2.99003
82 3Q72 GNP 0.0000000001056 0.75281 3.01205
83 1OE0 TTP 0.004374 0.43961 3.04348
84 1GOT GDP 0.000000006785 0.71593 3.04569
85 5I0H ADP BEF 0.0002253 0.49359 3.04569
86 4IHQ ADP 0.0002077 0.47081 3.04569
87 5MZN ADP 0.0005969 0.47056 3.04569
88 4YS0 ADP 0.001155 0.41384 3.04569
89 2EUG URA 0.01752 0.40192 3.05677
90 1GOJ ADP 0.0000001933 0.66641 3.09859
91 2XTZ GSP 0.000000001474 0.75785 3.10734
92 3ZFD ANP 0.00003396 0.52268 3.1339
93 3VX3 ADP 0.00009637 0.5091 3.22581
94 2FH5 GTP 0.0000000005418 0.76578 3.24324
95 1P72 ADP 0.00044 0.49713 3.29341
96 1QF5 GDP 0.00002052 0.58667 3.29949
97 4PFO ADP 0.0002266 0.5016 3.29949
98 1QF5 RPL 0.005812 0.48491 3.29949
99 4PJ3 ANP 0.001539 0.41684 3.29949
100 2C42 PYR 0.02393 0.40788 3.29949
101 2B8W ALF 5GP 0.0004603 0.48456 3.35366
102 1JJV ATP 0.00002599 0.48746 3.39806
103 3FYH ADP 0.0002796 0.49521 3.41615
104 5X40 ACP 0.0006058 0.4768 3.42466
105 3B7G ANP 0.0006153 0.46054 3.47826
106 3UIE ANP 0.00004369 0.51751 3.5
107 4GOX A3P 0.0001038 0.5143 3.51438
108 1W0J ADP 0.00001042 0.54999 3.5533
109 2ZPA ADP 0.0002531 0.48889 3.5533
110 1W0J ADP BEF 0.0003031 0.48512 3.5533
111 3TBK ANP 0.001046 0.43348 3.5533
112 2CK3 ANP 0.0003705 0.41966 3.5533
113 3CV2 OXL 0.01792 0.40002 3.5533
114 2ZE7 DST 0.008977 0.42406 3.55731
115 1KAO GDP 0.0000000008081 0.74974 3.59281
116 3H86 AP5 0.0002384 0.51354 3.64583
117 1S3G AP5 0.001139 0.48504 3.68664
118 4XTR ADP 0.00001349 0.475 3.68664
119 4XTR ATP 0.00001955 0.44339 3.68664
120 4XVU ATP 0.00002589 0.44024 3.68664
121 2Z5F A3P 0.003285 0.43718 3.69128
122 5UQW GDP 0.0000000004704 0.77916 3.7037
123 4GBM A3P 0.000585 0.47754 3.71517
124 2ZPT A3P 0.02097 0.43012 3.72881
125 4WZ6 ATP 0.00002074 0.54897 3.7931
126 1TU3 GNP 0.0000000001511 0.80672 3.79747
127 1Z06 GNP 0.0000000003966 0.78281 3.80711
128 2BCG GDP 0.0000000002608 0.64461 3.80711
129 2BIF ANP 0.0002561 0.51051 3.80711
130 2BIF SIN 0.0004286 0.51051 3.80711
131 1R6B ADP 0.0001024 0.49712 3.80711
132 1JJ7 ADP 0.00000201 0.49331 3.84615
133 5GVR LMR 0.002404 0.42759 3.84615
134 1FNN ADP 0.0003666 0.42224 3.85604
135 1VKJ A3P 0.003124 0.43824 3.85965
136 1MR3 G3D 0.0000000001491 0.7712 3.8674
137 5M04 GDP 0.00000000004352 0.80582 3.88889
138 3ZIA ADP 0.00001956 0.53698 3.95683
139 3ZIA ATP 0.00002028 0.53014 3.95683
140 2QG6 NMN 0.0005318 0.48674 4.0201
141 2FAH GDP 0.00002698 0.53033 4.06091
142 3DC4 ADP 0.00002659 0.49665 4.06091
143 2AWN ADP 0.000001542 0.47962 4.06091
144 2FSH ANP 0.002161 0.42554 4.06091
145 4AG5 ADP 0.00002315 0.54615 4.08163
146 2Q2Y ADP 0.0001317 0.53354 4.08719
147 2Q2Y MKR 0.0001261 0.53322 4.08719
148 3QF7 ANP 0.0003804 0.48037 4.10959
149 1ION ADP 0.0000243 0.52956 4.11523
150 3BOS CDP 0.00002592 0.52185 4.13223
151 3Q85 GNP 0.00000000001694 0.81012 4.14201
152 1ZUI SKM 0.0003776 0.50473 4.16667
153 2GDJ ANP 0.0001754 0.48315 4.16667
154 4HDO GNP 0.000000003245 0.74381 4.19162
155 1O3Y GTP 0.0000000005842 0.77123 4.21687
156 1J2J GTP 0.000000002336 0.57235 4.21687
157 1G3Q ADP 0.000008857 0.52849 4.21941
158 2J0V GDP 0.000000002624 0.71272 4.24528
159 3QBT GNP 0.0000000008893 0.55695 4.28571
160 5WRJ A3P 0.0009 0.47023 4.29043
161 4ZG4 VO4 ADP 0.0002325 0.40237 4.31472
162 3FIU POP 0.01729 0.40098 4.31472
163 3RWO GDP 0.000000000346 0.78894 4.32432
164 5L3V GDP 0.0000008078 0.5614 4.34783
165 5L3S GNP 0.000001792 0.47225 4.36242
166 2CHG ANP 0.00008892 0.50829 4.42478
167 1RYH GNP 0.000000002638 0.71701 4.4335
168 4PX9 ADP 0.0002137 0.48561 4.45205
169 2GCN GDP 0.000000008776 0.71049 4.47761
170 2GCO GNP 0.00000001074 0.69594 4.47761
171 4U00 ADP 0.000006314 0.47751 4.5082
172 5HGZ ACO 0.02201 0.40318 4.52675
173 1XMV ADP 0.00004352 0.51457 4.56853
174 1OS1 ATP 0.000185 0.51133 4.56853
175 1OS1 PYR 0.0001997 0.51133 4.56853
176 4NON GDP 0.000000002438 0.52556 4.61538
177 4KBF AMP 0.003087 0.41972 4.65753
178 4FRZ ADP 0.0000025 0.52656 4.66321
179 1Q20 PLO 0.004846 0.44562 4.68227
180 1Z08 GNP 0.000000001875 0.57315 4.70588
181 1J99 AND 0.01277 0.42416 4.77816
182 2A5F GTP 0.0000000005787 0.77474 4.82234
183 1NY5 ADP 0.0004955 0.47255 4.82234
184 4O33 TZN 0.02615 0.41961 4.82234
185 4O33 3PG 0.02615 0.41961 4.82234
186 1VG0 GDP 0.0000000001571 0.77949 4.83092
187 1VG8 GNP 0.0000000007161 0.77637 4.83092
188 3COB ADP 0.0000004017 0.5382 4.87805
189 2JAQ DCP 0.005225 0.43095 4.87805
190 1DAK DPU 0.0003249 0.51563 4.91071
191 2IYL GDP 0.000001349 0.58168 4.92958
192 1KY3 GDP 0.0000000008919 0.7436 4.94506
193 2W58 ADP 0.000008886 0.47283 4.9505
194 1RE0 GDP 0.00000000001512 0.79041 4.97738
195 4LJ9 ACP 0.0002367 0.47708 5.01475
196 2ZEJ GDP 0.000000002276 0.75145 5.07614
197 4M9Q GNP 0.0000000001118 0.62695 5.07614
198 1W5T ANP 0.0005688 0.4741 5.07614
199 1W5T ADP 0.000992 0.45811 5.07614
200 3FB4 AP5 0.001154 0.48475 5.09259
201 4TTQ ATP 0.00008072 0.49886 5.11628
202 3KJI ADP 0.00001186 0.54731 5.11811
203 1KO8 6PG 0.0004088 0.47886 5.14286
204 1FL2 FAD 0.03587 0.40805 5.16129
205 1H65 GDP 0.000005362 0.57481 5.18518
206 2D2F ADP 0.000185 0.41347 5.2
207 5KSP GDP 0.00000003857 0.63362 5.26316
208 5KUT GDP 0.000000007989 0.69001 5.29101
209 1KUV CA5 0.02917 0.40464 5.31401
210 2NCD ADP 0.0000046 0.58187 5.32995
211 4R43 GDP 0.00002687 0.52113 5.32995
212 4IDN GNP 0.0001642 0.41865 5.32995
213 4AF0 IMP 0.01352 0.41066 5.32995
214 5BUK FAD 0.04935 0.40485 5.32995
215 3BD9 A3P 0.004369 0.42053 5.35714
216 1IN4 ADP 0.00008594 0.51149 5.38922
217 1VG1 GDP 0.00000000004375 0.7962 5.40541
218 1VG9 GDP 0.0000000001009 0.77916 5.40541
219 1UKZ ADP 0.000823 0.48476 5.41872
220 1CJW COT 0.02626 0.40337 5.42169
221 1T5C ADP 0.0000002504 0.52517 5.44413
222 1XP8 AGS 0.00005708 0.49487 5.46448
223 4MKG AP5 0.0006934 0.49621 5.52995
224 3T1O GDP 0.0000000002894 0.7624 5.55556
225 1UJ2 ADP 0.0000996 0.52116 5.55556
226 1UJ2 C5P 0.00009987 0.5211 5.55556
227 1WF3 GNP 0.000000001474 0.76081 5.58376
228 1SVK ALF GDP 0.000000003764 0.74864 5.58376
229 1JWY GDP 0.00000005543 0.65824 5.58376
230 5KDO GDP 0.000000004199 0.59525 5.58376
231 1GP2 GDP 0.000000002899 0.57292 5.58376
232 1JWY ADP 0.00007788 0.5027 5.58376
233 3BFX A3P 0.0009007 0.40997 5.58376
234 1XTQ GDP 0.0000000003577 0.78166 5.64972
235 3REF GDP 0.00000001945 0.55031 5.6701
236 1YRB GDP 0.000000000141 0.78173 5.72519
237 2HF9 GSP 0.00000004879 0.5823 5.75221
238 2RGX AP5 0.001625 0.47925 5.82524
239 2BEK ATP 0.000566 0.40016 5.83658
240 2IXE ATP 0.0003058 0.48929 5.83756
241 1G3M PCQ 0.006503 0.4448 5.83756
242 3MGB PAP 0.006054 0.42429 5.83756
243 5XCO GDP 0.0000000002176 0.77276 5.84795
244 1IWE IMP 0.00004139 0.60322 5.9081
245 2BME GNP 0.000000001075 0.76463 5.91398
246 1YZN GNP 0.000000001219 0.54291 5.94595
247 1BO4 COA 0.006906 0.40873 5.95238
248 3FMI KAP 0.01351 0.40903 5.9761
249 2QQ0 THM 0.0001898 0.51243 5.97826
250 2QQ0 ANP 0.0002193 0.51243 5.97826
251 2QQ0 TMP 0.0002374 0.51069 5.97826
252 4MKF AP5 0.0007862 0.49454 5.99078
253 1BH2 GSP 0.00000001456 0.71666 6.03175
254 3FWY ADP 0.000001336 0.59561 6.05096
255 1TQ4 GDP 0.000000002054 0.5984 6.05327
256 4OI4 ATP 0.0002272 0.49765 6.08696
257 5I34 GDP 0.000002888 0.56989 6.09137
258 4WZA ADP 0.00009965 0.55906 6.09137
259 4WZA ACP 0.0001003 0.5589 6.09137
260 3RC3 ANP 0.003639 0.41439 6.09137
261 3DKP ADP 0.0005345 0.46059 6.12245
262 3IUY AMP 0.006218 0.41332 6.14035
263 4U5X GNP 0.00000001354 0.69468 6.17978
264 1M2O GNP 0.000000007437 0.72312 6.31579
265 1FP6 ADP 0.000008003 0.55545 6.34518
266 1Z6T ADP 0.000221 0.435 6.34518
267 4IEE AGS 0.004088 0.42423 6.34518
268 2PL3 ADP 0.0007549 0.44604 6.35593
269 4K81 GTP 0.000000004332 0.74034 6.43275
270 4QM7 GTP 0.00012 0.49084 6.43275
271 4V0K GDP 0.0000000004612 0.58033 6.50888
272 1GXU 2HP 0.003041 0.40838 6.59341
273 3KUD GDP 0.0000000005261 0.7664 6.62651
274 1NVU GTP 0.000000001553 0.75969 6.62651
275 1NVV GNP 0.000000001617 0.75881 6.62651
276 3DDC GNP 0.000000001797 0.75654 6.62651
277 1WQ1 GDP 0.0000000009103 0.58027 6.62651
278 1CLU DBG 0.000000003998 0.42833 6.62651
279 3H4S ADP 0.0000007196 0.5292 6.66667
280 1JI0 ATP 0.00004825 0.5243 6.66667
281 4WOP CTP 0.0008824 0.42374 6.66667
282 2OG2 MLI 0.00001759 0.4096 6.68524
283 2VB6 ADP BEF 0.0002654 0.49435 6.71141
284 2C5L GTP 0.0000000008172 0.77352 6.83761
285 2Y65 ADP 0.0000004593 0.53675 6.84932
286 3AB3 GDP 0.0000000009344 0.75432 6.85279
287 3CX8 GSP 0.000000003119 0.75014 6.85279
288 1F9V ADP 0.000004622 0.51619 6.85279
289 2C04 GCP 0.00001559 0.48822 6.85279
290 1S9D GDP 0.00000000007413 0.75275 6.89655
291 5O2T GSP 0.00000000107 0.54477 6.95187
292 2GJ8 ALF GDP 0.000000000158 0.5692 6.97674
293 2XT3 ADP 0.0000008274 0.5274 6.97674
294 1OXV ANP 0.00007251 0.49007 7.08215
295 2RCN GDP 0.0000000001371 0.76779 7.1066
296 3P4X ADP 0.0001367 0.47982 7.1066
297 4QOS ADP 0.0003459 0.44725 7.1066
298 3WQT ANP 0.02163 0.40058 7.1066
299 1FZQ GDP 0.00000000002678 0.80085 7.18232
300 4LC1 GDP 0.0000000005277 0.74051 7.4184
301 4D81 ADP 0.00008214 0.46342 7.42049
302 3RLF ANP 0.0003832 0.48654 7.43243
303 1ZJ6 G3D 0.000000000009085 0.82826 7.48663
304 2D7D ADP 0.00188 0.43512 7.5
305 5IRC GDP 0.00000006627 0.65081 7.52688
306 2W2X GSP 0.000000005494 0.71705 7.56757
307 3MD0 GDP 0.00000000001638 0.78723 7.60563
308 1KMQ GNP 0.00000002219 0.69392 7.6087
309 3E70 GDP 0.000001586 0.58212 7.62195
310 1YVD GNP 0.0000000008711 0.76913 7.69231
311 2HV8 GTP 0.00000000101 0.76597 7.8125
312 2IS6 ADP 0.0001054 0.49346 7.86802
313 3TK1 GDP 0.0000000000328 0.75273 7.87879
314 1TX4 ALF GDP 0.00000003368 0.53497 7.9096
315 4DSU GDP 0.0000000005596 0.78168 7.93651
316 3B9Q MLI 0.000007376 0.57874 7.94702
317 1BG2 ADP 0.0000001168 0.53725 8
318 1B0U ATP 0.0002986 0.48063 8.01527
319 1AQU A3P 0.002539 0.43855 8.08081
320 1YQT ADP 0.00001922 0.49016 8.12183
321 1FQK GDP 0.000000009611 0.55945 8.16327
322 5L3R GCP 0.000001821 0.47253 8.19113
323 1GWN GTP 0.00000001148 0.70154 8.29268
324 1DS6 GDP 0.000000001958 0.71397 8.33333
325 1I4D GDP 0.000000002417 0.69254 8.33333
326 1E96 GTP 0.00000003064 0.69275 8.37438
327 3M1I GTP 0.000000003314 0.74336 8.37696
328 2KIN ADP 0.0000001516 0.5331 8.40336
329 4C4P GNP 0.0000000004822 0.78489 8.41121
330 1PUJ GNP 0.00000000003283 0.81186 8.51064
331 4HI0 GDP 0.0000000307 0.56571 8.54271
332 3SBD GNP 0.00000003248 0.51428 8.55615
333 2OFW ADX 0.0002145 0.5213 8.65385
334 1Z0K GTP 0.0000000006809 0.76798 8.72093
335 1T8U A3P 0.003021 0.43895 8.82353
336 1T8U UAP SGN IDS SGN 0.01123 0.43351 8.82353
337 3A4M ADP 0.000009386 0.51782 8.84615
338 4DCT GDP 0.00000000001674 0.8158 8.88325
339 1S8F GDP 0.0000000005819 0.78378 8.88325
340 1YZG GDP 0.00000000001149 0.82348 8.93855
341 2XTN GTP 0.000001448 0.60512 8.97436
342 2FJU GSP 0.00000001688 0.69343 8.98876
343 3B5J 12D 0.00007883 0.47924 9.0535
344 1R4A GNP 0.0000000003255 0.78703 9.09091
345 1HE1 GDP 0.00000001233 0.57267 9.09091
346 1LVG ADP 0.000001844 0.54952 9.09091
347 2V7Q ATP 0.00001275 0.5428 9.09091
348 2V7Q ADP 0.0002355 0.47719 9.09091
349 4GDX GLU 0.006912 0.42457 9.23077
350 4P32 ADP 0.000437 0.48174 9.23695
351 1M7B GTP 0.000000005458 0.58513 9.23913
352 2GK6 ADP 0.001087 0.43074 9.39086
353 2QEN ADP 0.00002168 0.53765 9.42857
354 3IIJ ADP 0.00001925 0.52788 9.44444
355 2PEZ DAT 0.0001033 0.52898 9.49721
356 3BFV ADP 0.00001244 0.53672 9.5941
357 1B7T ADP 0.0001318 0.49484 9.61539
358 1KK8 BEF ADP 0.0001167 0.50264 9.74026
359 1OFH ADP 0.0001303 0.49507 9.77011
360 4DID GDP 0.000000006214 0.69514 9.84456
361 3KTA AP5 0.0001891 0.49007 9.89011
362 1NJF ADP 0.0000538 0.52129 10
363 1NJF AGS 0.00007247 0.51975 10
364 4BAS GNP 0.000000002385 0.73804 10.0503
365 1SQ5 ADP 0.00001694 0.51501 10.0649
366 5CK5 GDP 0.000000004936 0.68013 10.1266
367 1NF3 GNP 0.0000000362 0.51167 10.2564
368 1D2N ANP 0.002045 0.44717 10.2941
369 1QF9 C5P 0.001326 0.47808 10.3093
370 5HPY GDP 0.000000007274 0.70404 10.3448
371 1ZIN AP5 0.0007659 0.49397 10.4061
372 3GJ5 GDP 0.0000000003248 0.75532 10.4072
373 3GJ0 GDP 0.0000000002644 0.7545 10.4072
374 3GJ3 GDP 0.0000000002865 0.75287 10.4072
375 3GJ4 GDP 0.000000000337 0.74959 10.4072
376 3GJ8 GDP 0.0000000002517 0.72964 10.4072
377 2CJW GDP 0.00000000005284 0.78709 10.4167
378 1A4R GDP 0.000000004094 0.7197 10.4712
379 1A4R GNH 0.000000004585 0.71364 10.4712
380 2NGR GDP 0.0000000053 0.69838 10.4712
381 1GRN GDP 0.000000009707 0.69804 10.4712
382 4ITR GDP 0.00000001886 0.68775 10.4712
383 2UZI GTP 0.000000001029 0.76557 10.5769
384 5BXQ GDP 0.0000000001531 0.77066 10.6481
385 1IBR GNP 0.000000004236 0.73807 10.6481
386 2A9K GDP 0.0000000006032 0.75583 10.6952
387 4HUT ATP 0.01947 0.41121 10.9948
388 5N69 ADP 0.0001668 0.44994 11.0553
389 4H1V GNP 0.0000006819 0.54237 11.1111
390 5GJC ATP 0.0002057 0.47993 11.1675
391 3GJ7 GDP 0.0000000003579 0.74837 11.2245
392 5H56 ADP 0.0001995 0.51134 11.2821
393 5H56 TYD 0.0001995 0.51134 11.2821
394 1ZC3 GNP 0.000000001445 0.76124 11.4286
395 2QZ4 ADP 0.00006493 0.50937 11.4504
396 3T12 GDP ALF 0.0000000005396 0.60372 11.7647
397 1M7G ADX 0.0000228 0.56045 11.8483
398 1M7G AV2 0.000002033 0.56045 11.8483
399 1M7G ADP 0.00004828 0.54052 11.8483
400 1U8Z GDP 0.0000000009896 0.57923 11.9048
401 1OW3 GDP 0.000000009109 0.69936 11.9171
402 2A5J GDP 0.0000000000931 0.72234 12.0419
403 2CE7 ADP 0.00004876 0.51525 12.1827
404 2WIC GNP 0.0000000006972 0.71041 12.3596
405 4D0N GDP 0.00000000344 0.70256 12.4324
406 1AZT GSP 0.000000001473 0.76643 12.6904
407 1CS4 GSP 0.000000003678 0.5279 12.6904
408 1G6H ADP 0.000004849 0.48092 12.8405
409 4HAT GNP 0.000000003747 0.74348 12.8571
410 1WA5 GTP 0.000000005989 0.4906 13.0682
411 1Z2A GDP 0.000000000802 0.58393 13.0952
412 1Z0A GDP 0.000000000122 0.78013 13.2184
413 1W7J ADP BEF 0.0001531 0.44067 13.245
414 2ORV 4TA 0.004717 0.43642 13.2479
415 1SVI GDP 0.0000000001054 0.75233 13.3333
416 4QRH 0O2 0.008998 0.41593 13.3333
417 4NCN GTP 0.0000000001665 0.79791 13.4518
418 2HT6 GDP 0.0000000000126 0.79358 13.4518
419 3T5G GDP 0.0000000001346 0.77813 13.8158
420 5TB5 GDP 0.0000000001356 0.77797 14
421 5TAR GDP 0.0000000001988 0.68597 14.1892
422 1XX6 ADP 0.0005117 0.46148 14.6597
423 5UFQ GNP 0.000000000551 0.56176 14.7541
424 3RAB GNP 0.0000000001836 0.80254 14.7929
425 1G16 GDP 0.000000004359 0.72529 15.2941
426 5UWP GNP 0.000000003397 0.7456 15.3846
427 5UWI GNP 0.000000003366 0.74302 15.3846
428 5UWT GNP 0.000000003769 0.74058 15.3846
429 5UWQ GNP 0.000000002656 0.53487 15.3846
430 5UWU GNP 0.000000002816 0.53425 15.3846
431 5UWJ GNP 0.000000003054 0.53353 15.3846
432 5UWR GNP 0.000000003477 0.53226 15.3846
433 5UWW GNP 0.000000003544 0.53219 15.3846
434 5UWO GNP 0.000000003575 0.53201 15.3846
435 5UWH GNP 0.000000003665 0.5317 15.3846
436 5UWS GNP 0.000000004378 0.52013 15.3846
437 5DI9 GNP 0.000000004537 0.51967 15.3846
438 1G7S GDP 0.000000000002083 0.82045 15.4822
439 1DAR GDP 0.00000000002273 0.80417 15.4822
440 3EC1 GDP 0.0000000002183 0.76343 15.4822
441 2ODE ALF GDP 0.000000003976 0.51541 15.6028
442 4YMU ATP 0.0001455 0.49359 15.8333
443 4B47 GDP 0.0000000000005089 0.8551 15.978
444 1F6B GDP 0.0000000007059 0.73949 16.1616
445 2WHX ADP 0.00003502 0.48038 16.2437
446 2JLR ANP 0.0003535 0.47714 16.2437
447 1UPT GTP 0.000000001437 0.74876 16.6667
448 2OM2 GDP 0.00000000282 0.60003 16.6667
449 3A1S GDP 0.0000001082 0.63687 17.0543
450 1CXZ GSP 0.00000001345 0.70146 17.4419
451 3W5J GDP 0.00000002359 0.59137 17.5127
452 1KSH GDP 0.00000000003955 0.82084 18.2796
453 1NRJ GTP 0.00000003827 0.67621 18.3486
454 3BC1 GNP 0.000000001273 0.76099 18.4615
455 1NN5 ANP 0.0001249 0.52322 18.6047
456 4CVN ADP 0.0000104 0.55709 18.8482
457 1MKY GDP 0.000000000001664 0.85709 19.5431
458 1ZD9 GDP 0.000000001594 0.6199 19.6809
459 4R98 GNH 0.000000002101 0.71254 19.9262
460 1GUA GNP 0.000000001982 0.53546 21.5569
461 1LFD GNP 0.000000001276 0.76095 21.8391
462 1Z0J GTP 0.0000000006696 0.54936 22.0339
463 1X1R GDP 0.000000002371 0.75057 23.5955
464 2WJG GDP 0.00000000002845 0.79962 26.0638
465 3PQC GDP 0.00000001099 0.63863 26.1538
466 3CH5 GDP 0.0000000002406 0.76144 28.8462
467 2WJH GDP 0.0000000001291 0.77414 29.5181
468 2WJH FLC 0.0000003043 0.61951 29.5181
469 5FG3 GDP 0.000000000001303 0.83698 29.6954
470 1FQJ GDP 0.000000004608 0.56713 30.9524
471 5DIF GNP 0.000000002956 0.53384 31.5789
472 4RD0 GDP 0.000000000001144 0.89968 35.7868
473 2QN6 GDP 0.00000000000007638 0.89124 36.0406
474 1KK1 GNP 0.00000000000007971 0.89001 42.3858
475 1Y3A GDP 0.00000000457 0.72751 50
Pocket No.: 2; Query (leader) PDB : 3U6K; Ligand: GDP; Similar sites found: 5
This union binding pocket(no: 2) in the query (biounit: 3u6k.bio1) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5HR5 FLC 0.03292 0.40194 1.77665
2 2J5V PCA 0.03853 0.40212 2.45232
3 1JBW ACQ 0.03521 0.40044 3.29949
4 2CK3 ADP 0.0002507 0.4026 3.5533
5 5E5U MLI 0.00539 0.40696 4.16667
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