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Receptor
PDB id Resolution Class Description Source Keywords
3VA0 2.2 Å EC: 3.1.13.- CRYSTAL STRUCTURE OF RNASE T IN COMPLEX WITH A DI-NUCLEOTIDE (GG) WITH ONE MG IN THE ACTIVE SITE ESCHERICHIA COLI DEDD NUCLEASES FAMILY EXO-NUCLEASE HYDROLASE-DNA COMPLEX
Ref.: HOW AN EXONUCLEASE DECIDES WHERE TO STOP IN TRIMMIN NUCLEIC ACIDS: CRYSTAL STRUCTURES OF RNASE T-PRODUC COMPLEXES NUCLEIC ACIDS RES. V. 40 8144 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CO B:302;
Invalid;
none;
submit data
58.933 Co [Co+2...
DG DG C:1;
D:1;
Valid;
Valid;
none;
none;
submit data
595.446 n/a P(=O)...
MG A:301;
B:301;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3NGZ 2.1 Å EC: 3.1.13.- CRYSTAL STRUCTURE OF RNASE T IN COMPLEX WITH A NON-PREFERRED (GC) WITH ONE MG IN THE ACTIVE SITE ESCHERICHIA COLI EXORIBONUCLEASE RNA PROCESSING RNA MATURATION PROTEIN-DNAINTERACTIONS PROTEIN-DNA COMPLEX EXO-NUCLEASE HYDROLASE-COMPLEX
Ref.: STRUCTURAL BASIS FOR RNA TRIMMING BY RNASE T IN STA 3'-END MATURATION NAT.CHEM.BIOL. V. 7 236 2011
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 3VA0 - DG DG n/a n/a
2 3NGZ - DG DC n/a n/a
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 3VA0 - DG DG n/a n/a
2 3NGZ - DG DC n/a n/a
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 3VA0 - DG DG n/a n/a
2 3NGZ - DG DC n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: DG DG; Similar ligands found: 68
No: Ligand ECFP6 Tc MDL keys Tc
1 DG DG 1 1
2 DC DG 0.719626 0.951219
3 DGP 0.693182 0.925
4 DG 0.693182 0.925
5 3PD UM3 0.685185 0.926829
6 DGI 0.684783 0.91358
7 DG DA DC DG 0.648438 0.963415
8 DGT 0.639175 0.91358
9 DG DC 0.608333 0.915663
10 CGP 0.577586 0.927711
11 DC DG DA DC 0.560606 0.939024
12 DA DU DG DA 0.560345 0.870588
13 DU DU DU DU BRU DG DU 0.559055 0.873563
14 DA DC DG DA 0.553957 0.927711
15 DC DG DT DA 0.52381 0.917647
16 DT DA DC DG 0.517007 0.917647
17 DA DT DA DA 0.5 0.858824
18 ALF 5GP 0.476636 0.837209
19 G3D 0.46789 0.876543
20 3GP 0.465347 0.8875
21 G G 0.461538 0.91358
22 G4P 0.459459 0.876543
23 G 0.456311 0.876543
24 5GP 0.456311 0.876543
25 GCP G 0.452174 0.8875
26 ALF GDP 0.451327 0.837209
27 GDP ALF 0.451327 0.837209
28 2GP 0.45098 0.876543
29 GDP 0.448598 0.865854
30 DI 0.446602 0.9
31 G U 0.444444 0.891566
32 GDP AF3 0.438596 0.837209
33 G C 0.4375 0.891566
34 GH3 0.4375 0.888889
35 GP2 0.435185 0.879518
36 G A A A 0.434109 0.9375
37 GMP 0.43299 0.802469
38 0O2 0.431034 0.876543
39 P2G 0.428571 0.829268
40 G2P 0.428571 0.879518
41 GSP 0.428571 0.825581
42 G G G RPC 0.426357 0.890244
43 GP3 0.425926 0.890244
44 GTP 0.423423 0.865854
45 A G 0.423077 0.925
46 GAV 0.421053 0.835294
47 P1G 0.420561 0.841463
48 U A G G 0.419847 0.925
49 GPG 0.418803 0.902439
50 GNH 0.418182 0.855422
51 GDP 7MG 0.418033 0.902439
52 GPX 0.417391 0.841463
53 CF2 0.417266 0.837209
54 SGP 0.415094 0.77907
55 APC G U 0.413534 0.925
56 DT MA7 DT 0.411348 0.83908
57 GPD 0.41129 0.870588
58 GMV 0.410714 0.845238
59 G2R 0.410256 0.902439
60 G G G C 0.407407 0.880952
61 GCP 0.40708 0.86747
62 G1R 0.40708 0.855422
63 GDC 0.404959 0.879518
64 GDD 0.404959 0.879518
65 GKE 0.404959 0.879518
66 A G C C 0.404412 0.879518
67 9GM 0.403509 0.845238
68 GNP 0.403509 0.845238
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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