Receptor
PDB id Resolution Class Description Source Keywords
3VA0 2.2 Å EC: 3.1.13.- CRYSTAL STRUCTURE OF RNASE T IN COMPLEX WITH A DI-NUCLEOTIDE (GG) WITH ONE MG IN THE ACTIVE SITE ESCHERICHIA COLI DEDD NUCLEASES FAMILY EXO-NUCLEASE HYDROLASE-DNA COMPLEX
Ref.: HOW AN EXONUCLEASE DECIDES WHERE TO STOP IN TRIMMIN NUCLEIC ACIDS: CRYSTAL STRUCTURES OF RNASE T-PRODUC COMPLEXES NUCLEIC ACIDS RES. V. 40 8144 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CO B:302;
Invalid;
none;
submit data
58.933 Co [Co+2...
DG DG C:1;
D:1;
Valid;
Valid;
none;
none;
submit data
595.446 n/a [P+](...
MG A:301;
B:301;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3NGZ 2.1 Å EC: 3.1.13.- CRYSTAL STRUCTURE OF RNASE T IN COMPLEX WITH A NON-PREFERRED (GC) WITH ONE MG IN THE ACTIVE SITE ESCHERICHIA COLI EXORIBONUCLEASE RNA PROCESSING RNA MATURATION PROTEIN-DNAINTERACTIONS PROTEIN-DNA COMPLEX EXO-NUCLEASE HYDROLASE-COMPLEX
Ref.: STRUCTURAL BASIS FOR RNA TRIMMING BY RNASE T IN STA 3'-END MATURATION NAT.CHEM.BIOL. V. 7 236 2011
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 3VA0 - DG DG n/a n/a
2 3NGZ - DG DC n/a n/a
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 3VA0 - DG DG n/a n/a
2 3NGZ - DG DC n/a n/a
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 3VA0 - DG DG n/a n/a
2 3NGZ - DG DC n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: DG DG; Similar ligands found: 71
No: Ligand ECFP6 Tc MDL keys Tc
1 DG DG 1 1
2 DC DG 0.719626 0.951219
3 DGP 0.693182 0.925
4 DG 0.693182 0.925
5 3PD UM3 0.685185 0.926829
6 DGI 0.684783 0.91358
7 DG DA DC DG 0.648438 0.963415
8 DA DC DG DA 0.643411 0.963415
9 DGT 0.639175 0.91358
10 DG DT DC 0.630252 0.906977
11 DU DU DU DU BRU DG DU 0.620968 0.896552
12 DG DC 0.608333 0.915663
13 CGP 0.577586 0.927711
14 DC DG DA DC 0.560606 0.939024
15 DA DU DG DA 0.560345 0.870588
16 DC DG DT DA 0.52381 0.917647
17 DT DA DC DG 0.517007 0.917647
18 DA DT DA DA 0.5 0.858824
19 G G 0.477876 0.925
20 ALF 5GP 0.476636 0.837209
21 G3D 0.46789 0.876543
22 GDP MG 0.46729 0.86747
23 3GP 0.465347 0.8875
24 BEF GDP 0.463636 0.837209
25 GTP MG 0.463636 0.86747
26 GDP BEF 0.462963 0.847059
27 G G U 0.462185 0.925
28 G4P 0.459459 0.876543
29 5GP 0.456311 0.876543
30 G 0.456311 0.876543
31 GDP ALF 0.451327 0.837209
32 2GP 0.45098 0.876543
33 GDP 0.448598 0.865854
34 DI 0.446602 0.9
35 GDP AF3 0.438596 0.837209
36 G C 0.4375 0.891566
37 GH3 0.4375 0.888889
38 GP2 0.435185 0.879518
39 G A A A 0.434109 0.9375
40 GMP 0.43299 0.802469
41 0O2 0.431034 0.876543
42 GSP 0.428571 0.825581
43 G2P 0.428571 0.879518
44 P2G 0.428571 0.829268
45 G G G RPC 0.426357 0.890244
46 GP3 0.425926 0.890244
47 DU DU DU DU BRU DA DU 0.425532 0.83908
48 GTP 0.423423 0.865854
49 GCP G 0.421053 0.878049
50 GAV 0.421053 0.835294
51 P1G 0.420561 0.841463
52 U A G G 0.419847 0.925
53 GPG 0.418803 0.902439
54 GNH 0.418182 0.855422
55 GDP 7MG 0.418033 0.902439
56 GPX 0.417391 0.841463
57 CF2 0.417266 0.837209
58 SGP 0.415094 0.77907
59 APC G U 0.413534 0.925
60 DT MA7 DT 0.411348 0.83908
61 GPD 0.41129 0.870588
62 GMV 0.410714 0.845238
63 G2R 0.410256 0.902439
64 G G G C 0.407407 0.880952
65 GCP 0.40708 0.86747
66 G1R 0.40708 0.855422
67 GKE 0.404959 0.879518
68 GDC 0.404959 0.879518
69 GDD 0.404959 0.879518
70 A G C C 0.404412 0.879518
71 GNP 0.403509 0.845238
Similar Binding Sites (Proteins are less than 50% similar to leader)
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