Receptor
PDB id Resolution Class Description Source Keywords
3VQ2 2.48 Å NON-ENZYME: SIGNAL_HORMONE CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/LPS COMPLEX MUS MUSCULUS LEUCINE RICH REPEAT MD-2 RELATED LIPID RECOGNITION RECEPTORIMMUNITY LIPID BINDING GLYCOSYLATION SECRETED IMMUNE SY
Ref.: STRUCTURAL BASIS OF SPECIES-SPECIFIC ENDOTOXIN SENS INNATE IMMUNE RECEPTOR TLR4/MD-2 PROC.NATL.ACAD.SCI.USA V. 109 7421 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
LP4 LP5 MYR DAO D:300;
Valid;
none;
submit data
1768.32 n/a P(=O)...
LP4 MYR LP5 DAO C:300;
Valid;
none;
submit data n/a n/a n/a n/a
NAG A:800;
A:801;
A:804;
Part of Protein;
Part of Protein;
Invalid;
none;
none;
none;
submit data
221.208 C8 H15 N O6 CC(=O...
NAG NAG A:802;
B:701;
Part of Protein;
Part of Protein;
none;
none;
submit data
408.404 n/a O=C(N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3VQ2 2.48 Å NON-ENZYME: SIGNAL_HORMONE CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/LPS COMPLEX MUS MUSCULUS LEUCINE RICH REPEAT MD-2 RELATED LIPID RECOGNITION RECEPTORIMMUNITY LIPID BINDING GLYCOSYLATION SECRETED IMMUNE SY
Ref.: STRUCTURAL BASIS OF SPECIES-SPECIFIC ENDOTOXIN SENS INNATE IMMUNE RECEPTOR TLR4/MD-2 PROC.NATL.ACAD.SCI.USA V. 109 7421 2012
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 286 families.
1 3VQ2 - LP4 MYR LP5 DAO n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 3VQ2 - LP4 MYR LP5 DAO n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 174 families.
1 3VQ2 - LP4 MYR LP5 DAO n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: LP4 LP5 MYR DAO; Similar ligands found: 5
No: Ligand ECFP6 Tc MDL keys Tc
1 LP4 LP5 MYR DAO 1 1
2 LP5 LP4 0.76 1
3 LP4 LP5 0.76 1
4 PA1 PO4 FTT FTT GCS FTT PO4 KDO MYR 0.624242 0.985075
5 LP5 0.51145 0.911765
Ligand no: 2; Ligand: LP4 MYR LP5 DAO; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3VQ2; Ligand: LP4 LP5 MYR DAO; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 3vq2.bio1) has 42 residues
No: Leader PDB Ligand Sequence Similarity
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