-->
Receptor
PDB id Resolution Class Description Source Keywords
3VYW 2.49 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF MNMC2 FROM AQUIFEX AEOLICUS AQUIFEX AEOLICUS TRNA WOBBLE URIDINE MODIFICATION ENZYME GENETIC CODE 5- METHYLAMINOMETHYL-2-THIOURIDINE METHYLTRANSFERASE 2-CODONSTRUCTURAL GENOMICS NPPSFA NATIONAL PROJECT ON PROTEIN STAND FUNCTIONAL ANALYSES RIKEN STRUCTURAL GENOMICS/PROTEOMIINITIATIVE RSGI TRANSFERASE
Ref.: CHARACTERIZATION AND STRUCTURE OF THE AQUIFEX AEOLI PROTEIN DUF752: A BACTERIAL TRNA-METHYLTRANSFERASE FUNCTIONING WITHOUT THE USUALLY FUSED OXIDASE DOMAI J.BIOL.CHEM. 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
BEN B:402;
C:402;
Invalid;
Invalid;
none;
none;
submit data
120.152 C7 H8 N2 [H]/N...
SAM A:501;
B:401;
C:401;
D:401;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
398.437 C15 H22 N6 O5 S C[S@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3VYW 2.49 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF MNMC2 FROM AQUIFEX AEOLICUS AQUIFEX AEOLICUS TRNA WOBBLE URIDINE MODIFICATION ENZYME GENETIC CODE 5- METHYLAMINOMETHYL-2-THIOURIDINE METHYLTRANSFERASE 2-CODONSTRUCTURAL GENOMICS NPPSFA NATIONAL PROJECT ON PROTEIN STAND FUNCTIONAL ANALYSES RIKEN STRUCTURAL GENOMICS/PROTEOMIINITIATIVE RSGI TRANSFERASE
Ref.: CHARACTERIZATION AND STRUCTURE OF THE AQUIFEX AEOLI PROTEIN DUF752: A BACTERIAL TRNA-METHYLTRANSFERASE FUNCTIONING WITHOUT THE USUALLY FUSED OXIDASE DOMAI J.BIOL.CHEM. 2012
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 3VYW - SAM C15 H22 N6 O5 S C[S@@+](CC....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 3VYW - SAM C15 H22 N6 O5 S C[S@@+](CC....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 3VYW - SAM C15 H22 N6 O5 S C[S@@+](CC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAM; Similar ligands found: 202
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 ADN 0.565789 0.773333
9 RAB 0.565789 0.773333
10 XYA 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 DTA 0.536585 0.789474
21 62X 0.535354 0.884615
22 MTA 0.53012 0.875
23 3DH 0.517647 0.849315
24 5AL 0.510417 0.743902
25 54H 0.510204 0.673913
26 VMS 0.510204 0.673913
27 0UM 0.51 0.857143
28 AMP 0.505747 0.707317
29 LMS 0.505747 0.666667
30 A 0.505747 0.707317
31 ABM 0.505618 0.753086
32 A5A 0.505155 0.688889
33 SON 0.5 0.746988
34 SSA 0.5 0.684783
35 6RE 0.5 0.78481
36 K15 0.5 0.883117
37 5AD 0.5 0.75
38 SRP 0.5 0.746988
39 LSS 0.49505 0.706522
40 CA0 0.494624 0.714286
41 A12 0.494505 0.705882
42 AP2 0.494505 0.705882
43 ME8 0.490385 0.841463
44 TSB 0.49 0.681319
45 53H 0.49 0.666667
46 DAL AMP 0.49 0.765432
47 5CA 0.49 0.684783
48 ACP 0.489362 0.694118
49 ADP 0.48913 0.690476
50 5AS 0.48913 0.648936
51 J7C 0.488889 0.772152
52 A2D 0.488889 0.690476
53 ZAS 0.488636 0.769231
54 9ZD 0.485149 0.729412
55 9ZA 0.485149 0.729412
56 8QN 0.485149 0.743902
57 GAP 0.484536 0.73494
58 AN2 0.483871 0.682353
59 A3S 0.483871 0.813333
60 A7D 0.483871 0.851351
61 GJV 0.483516 0.775
62 SRA 0.483146 0.694118
63 LAD 0.480769 0.752941
64 KAA 0.480769 0.698925
65 GSU 0.480769 0.722222
66 AMO 0.480392 0.746988
67 DSZ 0.480392 0.703297
68 52H 0.48 0.666667
69 M33 0.478723 0.722892
70 BA3 0.478261 0.690476
71 MAO 0.478261 0.82716
72 NEC 0.477778 0.75
73 AOC 0.477778 0.776316
74 DSH 0.477778 0.842105
75 SXZ 0.47619 0.894737
76 AHX 0.475728 0.701149
77 NVA LMS 0.475728 0.736264
78 Y3J 0.47561 0.706667
79 G5A 0.474227 0.684783
80 A3T 0.473684 0.8
81 B4P 0.473118 0.690476
82 AP5 0.473118 0.690476
83 A3N 0.472527 0.766234
84 KB1 0.471698 0.833333
85 PRX 0.46875 0.73494
86 APC 0.46875 0.705882
87 AT4 0.468085 0.686047
88 PAJ 0.466019 0.712644
89 4AD 0.466019 0.759036
90 RBY 0.463918 0.72619
91 ADP PO3 0.463918 0.728395
92 ADV 0.463918 0.72619
93 ADX 0.463158 0.666667
94 MHZ 0.463158 0.82716
95 AU1 0.463158 0.674419
96 YAP 0.462963 0.738095
97 TXA 0.462264 0.72619
98 NB8 0.462264 0.72093
99 A3G 0.461538 0.802632
100 VRT 0.459184 0.842105
101 XAH 0.458716 0.715909
102 YSA 0.458716 0.684783
103 HEJ 0.458333 0.690476
104 50T 0.458333 0.682353
105 ATP 0.458333 0.690476
106 LEU LMS 0.457143 0.717391
107 7D7 0.45679 0.723684
108 KH3 0.455357 0.871795
109 ACQ 0.454545 0.694118
110 AR6 0.453608 0.710843
111 APR 0.453608 0.710843
112 AQP 0.453608 0.690476
113 5FA 0.453608 0.690476
114 NSS 0.451923 0.703297
115 FA5 0.449541 0.746988
116 A5D 0.44898 0.789474
117 AD9 0.44898 0.674419
118 AGS 0.44898 0.678161
119 SAP 0.44898 0.678161
120 PTJ 0.448598 0.72093
121 YLB 0.448276 0.758621
122 YLP 0.447368 0.738636
123 8X1 0.446602 0.680851
124 D3Y 0.446602 0.792208
125 ADP ALF 0.445545 0.678161
126 ALF ADP 0.445545 0.678161
127 3AM 0.444444 0.674699
128 MYR AMP 0.444444 0.776471
129 OAD 0.443396 0.73494
130 2VA 0.443299 0.779221
131 S8M 0.442308 0.831169
132 OOB 0.442308 0.722892
133 TYR AMP 0.441441 0.759036
134 6YZ 0.441176 0.694118
135 ADP VO4 0.441176 0.702381
136 VO4 ADP 0.441176 0.702381
137 T99 0.44 0.686047
138 TAT 0.44 0.686047
139 ANP 0.44 0.674419
140 WAQ 0.439252 0.75
141 B5Y 0.436364 0.717647
142 8PZ 0.436364 0.684783
143 F0P 0.435897 0.844156
144 YLC 0.435897 0.755814
145 AAT 0.435644 0.797468
146 1ZZ 0.435185 0.755814
147 9K8 0.435185 0.663158
148 3OD 0.435185 0.73494
149 NVA 2AD 0.434343 0.855263
150 00A 0.433962 0.689655
151 DLL 0.433962 0.722892
152 ARG AMP 0.433628 0.727273
153 7MD 0.433628 0.715909
154 ATF 0.431373 0.666667
155 SO8 0.43 0.792208
156 3UK 0.429907 0.714286
157 A6D 0.429907 0.72619
158 9X8 0.429907 0.717647
159 F2R 0.429752 0.7
160 5SV 0.428571 0.741176
161 AMP DBH 0.428571 0.714286
162 TYM 0.42735 0.746988
163 WSA 0.42735 0.692308
164 9SN 0.427273 0.681818
165 AHZ 0.426087 0.755814
166 P5A 0.425926 0.691489
167 B5V 0.425926 0.705882
168 PR8 0.425926 0.744186
169 A A 0.425926 0.710843
170 3NZ 0.425926 0.807692
171 A1R 0.424528 0.709302
172 2A5 0.424242 0.674419
173 7MC 0.423729 0.719101
174 B5M 0.423423 0.717647
175 7D5 0.422222 0.658824
176 JB6 0.422018 0.709302
177 FYA 0.422018 0.722892
178 AYB 0.421488 0.75
179 A22 0.419048 0.682353
180 MAP 0.419048 0.659091
181 2AM 0.417582 0.666667
182 TAD 0.417391 0.712644
183 A3P 0.416667 0.686747
184 ADP BMA 0.416667 0.714286
185 25A 0.415094 0.690476
186 YLA 0.413223 0.719101
187 8Q2 0.411765 0.663158
188 A3R 0.411215 0.709302
189 ADQ 0.411215 0.694118
190 48N 0.410256 0.72093
191 0XU 0.41 0.824324
192 GA7 0.408696 0.72619
193 7D3 0.40625 0.643678
194 PAP 0.405941 0.678571
195 DQV 0.405172 0.702381
196 OVE 0.404255 0.662791
197 4UV 0.403509 0.697674
198 AF3 ADP 3PG 0.403361 0.712644
199 3AD 0.402299 0.783784
200 CMP 0.402062 0.691358
201 2BA 0.402062 0.682927
202 7C5 0.4 0.731707
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3VYW; Ligand: SAM; Similar sites found with APoc: 981
This union binding pocket(no: 1) in the query (biounit: 3vyw.bio3) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 3EGI ADP None
2 2BOS GLA GAL GLC NBU None
3 2BOS GLA GAL GLC None
4 6F9Q NAD None
5 2JB2 FAD 0.974026
6 2JB2 PHE 0.974026
7 2B4R NAD 0.974026
8 2B4R AES 0.974026
9 5EJ2 NAD 0.974026
10 2HJR APR 0.974026
11 6B92 SAH 1.02041
12 4RDI ATP 1.04167
13 4RDH AMP 1.04167
14 2WSB NAD 1.1811
15 6GFK SAH 1.19522
16 4EMI NAD 1.2987
17 4EMI FAD 1.2987
18 6ECW SAH 1.2987
19 6ECU SAH 1.2987
20 6C8R SAH 1.2987
21 6C8R EQV 1.2987
22 1K3T BRZ 1.2987
23 1HYH NAD 1.2987
24 5YU3 NAD 1.2987
25 5YU3 PRO 1.2987
26 2ATJ BHO 1.2987
27 1X14 NAD 1.49626
28 5FFF 5XC 1.55642
29 5FFF NAP 1.55642
30 1LVL FAD 1.62338
31 4PIO SAH 1.62338
32 4PIO AVI 1.62338
33 5AHO TLA 1.62338
34 1LVL NAD 1.62338
35 1GZ6 NAI 1.62338
36 1YBH FAD 1.62338
37 6EL3 NAP 1.62338
38 1GUZ NAD 1.62338
39 2V6G NAP 1.62338
40 1RKX NAD 1.62338
41 1RJW ETF 1.62338
42 1RJD SAM 1.62338
43 4G5H UD7 1.62338
44 4G5H NAP 1.62338
45 1RRC ADP 1.66113
46 1EJ0 SAM 1.66667
47 5Y8L NAD 1.69492
48 5Y8L HUI 1.69492
49 2YN4 39J 1.69492
50 4BQS ADP 1.70455
51 5OJ7 AR6 1.74825
52 1LLU NAD 1.75439
53 1I1N SAH 1.76991
54 4EA7 JB2 1.81818
55 4EA7 COA 1.81818
56 5T9F NAP 1.84502
57 5T9F TYR 1.84502
58 5T9E NAP 1.84502
59 1IY8 NAD 1.87266
60 1DDU DDU 1.88679
61 1G60 SAM 1.92308
62 3BGD PM6 1.92308
63 3BGD SAH 1.92308
64 1G6H ADP 1.94553
65 6FDF SAH 1.94805
66 1XHC FAD 1.94805
67 1H82 FAD 1.94805
68 5U8U FAD 1.94805
69 1H82 GZZ 1.94805
70 5G3U FDA 1.94805
71 1D4D FAD 1.94805
72 2AWN ADP 1.94805
73 2YVF FAD 1.94805
74 2YVF NAD 1.94805
75 1T26 NAI 1.94805
76 1T26 GBD 1.94805
77 4MO2 FDA 1.94805
78 5G3U ITW 1.94805
79 3E1T FAD 1.94805
80 6F97 FAD 1.94805
81 4MO2 FAD 1.94805
82 5Y77 FAD 1.94805
83 4MIG G3F 1.94805
84 4USQ FAD 1.94805
85 4USR FAD 1.94805
86 4OM8 NAD 1.94805
87 5ZBC FAD 1.94805
88 4Z0H NAD 1.94805
89 6FHO FAD 1.94805
90 3WLE NAD 1.94805
91 3GFB NAD 1.94805
92 5EOW FAD 1.94805
93 1PL6 572 1.94805
94 1LDN NAD 1.94805
95 3NFD COA 1.96078
96 3RJ5 NAD 1.9685
97 4BUZ OAD 2.03252
98 4BUZ NAD 2.03252
99 4BUZ OCZ 2.03252
100 1YC5 NCA 2.03252
101 3D3W NAP 2.04918
102 1PR9 NAP 2.04918
103 2AOT SAH 2.05479
104 1JQD SAH 2.05479
105 1L1E SAH 2.09059
106 1XX6 ADP 2.09424
107 1XKQ NDP 2.14286
108 5UAV NDP 2.17391
109 5UAV TFB 2.17391
110 6EQS BV8 2.18182
111 3RIY NAD 2.1978
112 6ARJ SAH 2.27273
113 6ARJ BW4 2.27273
114 3QJ4 FAD 2.27273
115 4Y30 49L 2.27273
116 4Y30 SAH 2.27273
117 4AP3 NAP 2.27273
118 4AP3 FAD 2.27273
119 5BVA FAD 2.27273
120 5DX8 SFG 2.27273
121 1F3L SAH 2.27273
122 3ICT FAD 2.27273
123 5DXA SFG 2.27273
124 5DX1 SFG 2.27273
125 3ICS FAD 2.27273
126 4NEC SAH 2.27273
127 4NTD FAD 2.27273
128 3ICR FAD 2.27273
129 5DWQ SFG 2.27273
130 1Q9I FAD 2.27273
131 1Q9I TEO 2.27273
132 5DX0 SFG 2.27273
133 5FUB SAH 2.27273
134 2Q0L FAD 2.27273
135 1PN0 FAD 2.27273
136 5HSA FAS 2.27273
137 3ICS ADP 2.27273
138 4U8P FDA 2.27273
139 4U8P UDP 2.27273
140 1PN0 IPH 2.27273
141 4HA6 FAD 2.27273
142 3ICT ADP 2.27273
143 2C7G FAD 2.27273
144 2C7G ODP 2.27273
145 3NTD FAD 2.27273
146 1V8B NAD 2.27273
147 3NTA FAD 2.27273
148 2GN4 NDP 2.27273
149 1J0X NAD 2.27273
150 2RGJ FAD 2.27273
151 3H9E NAD 2.27273
152 4UP4 GAL NAG 2.27273
153 3I6I NDP 2.27273
154 2GN4 UD1 2.27273
155 4W6Z 8ID 2.27273
156 1N1G BCP 2.27273
157 1R6D NAD 2.27273
158 1OFL NGK GCD 2.27273
159 1GOJ ADP 2.27273
160 3TK1 GDP 2.27273
161 1EBF NAD 2.27273
162 1RM0 D6P 2.27273
163 1RM0 NAI 2.27273
164 1R6D DAU 2.27273
165 2AG8 NAP 2.28137
166 3OFK SAH 2.31481
167 2VT3 ATP 2.32558
168 1K4M CIT 2.34742
169 1WP4 NDP 2.42215
170 2OBF F83 2.42215
171 2OBF SAH 2.42215
172 2CVZ NDP 2.42215
173 3MBI HSX 2.43902
174 1G0N PHH 2.4735
175 1G0N NDP 2.4735
176 3GCZ SAM 2.48227
177 3ZV6 4HB 2.4911
178 3ZV6 NAD 2.4911
179 1I9G SAM 2.5
180 2WA2 SAM 2.53623
181 3PT9 SAH 2.5974
182 3DMH SAM 2.5974
183 4FWE FAD 2.5974
184 3X0D SAH 2.5974
185 2YG3 FAD 2.5974
186 2VVL FAD 2.5974
187 2VVM FAD 2.5974
188 4TXI FAD 2.5974
189 4YNU FAD 2.5974
190 4YNU LGC 2.5974
191 3DMH GMP 2.5974
192 6GAR FAD 2.5974
193 5ZYN FAD 2.5974
194 5O9F NAD 2.5974
195 5O9F 9ON 2.5974
196 2E5V FAD 2.5974
197 2A92 NAI 2.5974
198 4C3Y FAD 2.5974
199 4AT0 FAD 2.5974
200 3OZ2 FAD 2.5974
201 3C6K SPD 2.5974
202 1GY8 NAD 2.5974
203 4C3Y ANB 2.5974
204 5NA1 FAD 2.5974
205 2AQJ FAD 2.5974
206 2AQJ TRP 2.5974
207 5KKA 6V0 2.5974
208 3TKY SAH 2.5974
209 6BWL NAD 2.5974
210 1CDO NAD 2.5974
211 5KJW 53C 2.5974
212 4RSL FAD 2.5974
213 5Z20 NAI 2.5974
214 1F8F NAD 2.5974
215 1U8X NAD 2.5974
216 5X7Q GLC GLC GLC 2.5974
217 3C6K MTA 2.5974
218 2C5A NAD 2.5974
219 2C5A GDC 2.5974
220 2GDZ NAD 2.62172
221 3RFV 15L 2.62172
222 3RFV NAI 2.62172
223 5ZRR 9J3 2.64151
224 2OHV NHL 2.65152
225 6DUB SAH 2.7027
226 3OU2 SAH 2.75229
227 1XTP SAI 2.75591
228 4YJK URA 2.77778
229 4I5I NAD 2.78746
230 1ZK4 NAP 2.78884
231 4NBU NAI 2.8
232 3LKZ SFG 2.80374
233 1NV8 MEQ 2.8169
234 1NV8 SAM 2.8169
235 2JKY 5GP 2.8169
236 4E13 NAD 2.82686
237 5JE0 AZ8 2.83401
238 5JE0 SAH 2.83401
239 5GWT SIN 2.8777
240 5GWT NAD 2.8777
241 1BDB NAD 2.88809
242 4YRY FAD 2.89855
243 4D79 ATP 2.89855
244 4YRY NAD 2.89855
245 1G55 SAH 2.92208
246 2RAB NAD 2.92208
247 2RAB FAD 2.92208
248 2WPF WPF 2.92208
249 4ONQ SFG 2.92208
250 2HQM FAD 2.92208
251 2WPF FAD 2.92208
252 2NPX NAD 2.92208
253 2NPX FAD 2.92208
254 4M52 FAD 2.92208
255 4KRI SAH 2.92208
256 1PJS NAD 2.92208
257 2A8X FAD 2.92208
258 3KLJ FAD 2.92208
259 5BUK FAD 2.92208
260 6FP4 FAD 2.92208
261 6FP4 E1T 2.92208
262 2BHZ MAL 2.92208
263 4M52 M52 2.92208
264 5JAQ NAI 2.92208
265 1BW9 NAD 2.92208
266 1SOW NAD 2.92208
267 2QA1 FAD 2.92208
268 3OND ADN 2.92208
269 3OND NAD 2.92208
270 1NAA ABL 2.92208
271 1NAA 6FA 2.92208
272 3GDN HBX 2.92208
273 3GDN FAD 2.92208
274 3WGT FAD 2.92208
275 3G5S FAD 2.92208
276 5KOX FAD 2.92208
277 5KOX RFP 2.92208
278 1PS9 FAD 2.92208
279 3WGT QSC 2.92208
280 2EFJ SAH 2.92208
281 1O97 FAD 2.92208
282 2C31 TZD 2.92208
283 2C31 ADP 2.92208
284 1O97 AMP 2.92208
285 1OMO NAD 2.92208
286 5MQ6 NDP 2.92208
287 1C0I FAD 2.92208
288 1C0I BE2 2.92208
289 2DBZ NAP 2.92208
290 4YKG NAD 2.92208
291 4YKG FAD 2.92208
292 1EZ4 NAD 2.92208
293 1RLZ NAD 2.92208
294 2OG2 MLI 2.92208
295 3W8X FAD 2.92208
296 3W8X FTK 2.92208
297 6DNT NAD 2.92208
298 5YAP NAI 2.92208
299 1FL2 FAD 2.92208
300 2P41 SAH 2.95082
301 4Y9D NAI 2.95082
302 5MGZ SAH 2.9661
303 1Z3C SA8 3.02013
304 3RKR NAP 3.05344
305 3DUV KDO 3.05344
306 3O7W SAM 3.06122
307 3H8V ATP 3.08219
308 2PWY SAH 3.10078
309 4OBW SAM 3.11284
310 5JGL SAM 3.11419
311 2YY7 NAD 3.20513
312 3MQ2 SAH 3.21101
313 3NUG NAD 3.23887
314 2JAH NDP 3.23887
315 2JAP NDP 3.23887
316 5U19 827 3.24675
317 5U19 SAH 3.24675
318 2IZ1 ATR 3.24675
319 4N49 SAM 3.24675
320 4ZCC FAD 3.24675
321 4ZCC NAI 3.24675
322 3SSO SAH 3.24675
323 4UCI SAM 3.24675
324 5TTJ FAD 3.24675
325 5TS5 FAD 3.24675
326 5X62 SAH 3.24675
327 1GR0 NAD 3.24675
328 3CTY FAD 3.24675
329 3ZNN FAD 3.24675
330 3ZNN 4WL 3.24675
331 3QVP FAD 3.24675
332 3NT6 FAD 3.24675
333 4D5G FAD 3.24675
334 4D5G TPP 3.24675
335 1KNR FAD 3.24675
336 1GV0 NAD 3.24675
337 4DPL NAP 3.24675
338 1R37 NAD 3.24675
339 2G2Y MLI 3.24675
340 3RC1 TLO 3.24675
341 3RC1 NAP 3.24675
342 6H3O FAD 3.24675
343 4ZGS NAD 3.24675
344 3Q9T FAY 3.24675
345 2O4C NAD 3.24675
346 1QAN SAH 3.27869
347 6AA8 NAD 3.31126
348 4FZV SAM 3.34728
349 5OJL TXP 3.3557
350 5DM1 5D7 3.37079
351 5DM1 SAH 3.37079
352 4NFE BEN 3.37553
353 1WY7 SAH 3.38164
354 2DTX BMA 3.40909
355 3THR C2F 3.41297
356 5GVR LMR 3.4188
357 1B0U ATP 3.43511
358 3QFA FAD 3.44828
359 2BZG SAH 3.44828
360 4BLW AMP 3.46021
361 4BLW SAH 3.46021
362 1NFQ NAI 3.46154
363 2HMT NAI 3.47222
364 5WUW NAP 3.48432
365 4R6W SAH 3.48837
366 4R6W PC 3.48837
367 5FTW SAH 3.51562
368 3GU3 SAH 3.52113
369 2Q2V NAD 3.52941
370 2PS1 ORO 3.53982
371 3VPB GLU 3.5461
372 3P2E SAH 3.55556
373 3LCV SAM 3.55872
374 3M6W SAM 3.57143
375 1LSS NAD 3.57143
376 5E72 SAM 3.57143
377 5J5Z FAD 3.57143
378 4IV9 FAD 3.57143
379 1RSG FAD 3.57143
380 4KIB SAH 3.57143
381 1YY5 FAD 3.57143
382 1BZL FAD 3.57143
383 1BZL GCG 3.57143
384 1NW5 SAM 3.57143
385 5J60 FAD 3.57143
386 3UOY NAP 3.57143
387 3UOY FAD 3.57143
388 3HDY FAD 3.57143
389 3HDY FDA 3.57143
390 3HDY GDU 3.57143
391 1V6A TRE 3.57143
392 5MIT NAP 3.57143
393 5MIT FAD 3.57143
394 3AB1 FAD 3.57143
395 5FJN BE2 3.57143
396 5FJN FAD 3.57143
397 1DLJ NAI 3.57143
398 1DLJ UGA 3.57143
399 5MZI FYK 3.57143
400 5MZI FAD 3.57143
401 1YKJ PHB 3.57143
402 1YKJ FAD 3.57143
403 5MLR GRQ 3.57143
404 5MLR NAP 3.57143
405 1FP1 SAH 3.57143
406 5DNK SAH 3.57143
407 4RVG SAM 3.57143
408 4RVG TYD 3.57143
409 6C5B SAH 3.57143
410 3FG2 FAD 3.57143
411 3LU1 NAD 3.57143
412 5DY5 5GR 3.57143
413 1GPJ CIT 3.57143
414 3DUW SAH 3.58744
415 2D2F ADP 3.6
416 4YUW 4JU 3.61842
417 4YUW S4M 3.61842
418 3ELW GP3 3.66667
419 3ELW SAM 3.66667
420 1P77 ATR 3.67647
421 5GM1 SAH 3.7037
422 3T7S SAM 3.73134
423 4X8O AP5 3.73832
424 2HNK SAH 3.76569
425 5FUI APY 3.78788
426 3K8D KDO 3.78788
427 4YAG NAI 3.80623
428 5U32 GDP 3.81356
429 3LCC SAH 3.82979
430 5ZI9 FLC 3.84615
431 6CI9 NAP 3.861
432 3ACC 5GP 3.8674
433 3EF0 ALF 3.8961
434 1X87 NAD 3.8961
435 5TWB FAD 3.8961
436 6GAS FAD 3.8961
437 5X68 FAD 3.8961
438 4ZVV NAD 3.8961
439 5UR0 NAD 3.8961
440 3A4V PYR 3.8961
441 3A4V NAD 3.8961
442 6AR9 3L4 3.8961
443 1SB8 NAD 3.8961
444 1SB8 UD2 3.8961
445 4ZVV GN0 3.8961
446 1TDF FAD 3.8961
447 2B5W NAP 3.8961
448 5OVK NDP 3.90625
449 4JLS 3ZE 3.94737
450 3EVF SAH 3.97112
451 3EVF GTA 3.97112
452 4POO SAM 4
453 4O0L NDP 4
454 3G89 SAM 4.01606
455 1XHL NDP 4.0404
456 5THQ NDP 4.04412
457 3GRU AMP 4.0678
458 4U00 ADP 4.09836
459 5GT9 NAP 4.18251
460 3WMX NAD 4.18994
461 3TKA SAM 4.22078
462 3S1S SAH 4.22078
463 1V59 FAD 4.22078
464 4DCM SAM 4.22078
465 5YB7 FAD 4.22078
466 6F7L FAD 4.22078
467 5YB7 ORN 4.22078
468 1FEC FAD 4.22078
469 3T31 FAD 4.22078
470 3T31 DCQ 4.22078
471 1QO8 FAD 4.22078
472 1V59 NAD 4.22078
473 4K5S FAD 4.22078
474 4K5S PM0 4.22078
475 6F3N ADN 4.22078
476 6F3N NAD 4.22078
477 1ELI PYC 4.22078
478 6F3M NAD 4.22078
479 2Q1S NAI 4.22078
480 4BJZ FAD 4.22078
481 4BJZ P3A 4.22078
482 2YYY NAP 4.22078
483 3NDJ SAH 4.22078
484 3NDJ JHZ 4.22078
485 1SAY PYR 4.22078
486 1U1I NAD 4.22078
487 4TQG NDP 4.22078
488 5FWA J7C 4.22078
489 1A5Z NAD 4.22078
490 1F8G NAD 4.22078
491 1WDK NAD 4.22078
492 1MZV AMP 4.25532
493 2CUL FAD 4.31034
494 4FN4 NAD 4.33071
495 1GXU 2HP 4.3956
496 3OZG SSI 4.4
497 1XSE NDP 4.40678
498 2EWM NAD 4.41767
499 5ZW3 SAH 4.44444
500 5BW4 SAM 4.49438
501 1UWK URO 4.54545
502 1UWK NAD 4.54545
503 5MBX SP5 4.54545
504 5MBX FAD 4.54545
505 2JJQ SAH 4.54545
506 4REP FAD 4.54545
507 5M67 3D1 4.54545
508 5M67 ADE 4.54545
509 5M67 NAD 4.54545
510 4Z24 FAD 4.54545
511 2CDC XYP 4.54545
512 5T67 JHZ 4.54545
513 1FP2 SAH 4.54545
514 4JJF N2I 4.54545
515 4JJF FE9 4.54545
516 5T67 SAH 4.54545
517 1WVG APR 4.54545
518 1SC6 NAD 4.54545
519 3ABI NAD 4.54545
520 1DSS NAD 4.54545
521 2CDC XYS 4.54545
522 5XWV NDP 4.54545
523 1ZGS XMM 4.54545
524 1UP7 NAD 4.54545
525 5XWV 8H6 4.54545
526 3CH6 NAP 4.54545
527 3CH6 311 4.54545
528 1L7E NAI 4.54545
529 2CDC NAP 4.54545
530 2YVJ FAD 4.58716
531 2YVJ NAI 4.58716
532 1Q0S SAH 4.6332
533 1GEG NAD 4.6875
534 4K26 SFF 4.71014
535 4K26 NDP 4.71014
536 1JQ3 AAT 4.72973
537 1S7G APR 4.74308
538 1S7G NAD 4.74308
539 3SJ7 NDP 4.7619
540 5M58 SAH 4.78261
541 4XZ3 COA 4.78261
542 4XYM COA 4.78261
543 5OCM NAP 4.811
544 1DJL NAP 4.83092
545 1VR0 3SL 4.8583
546 3TLJ SAH 4.87013
547 5WP4 SAH 4.87013
548 4RPL FAD 4.87013
549 4RPL 3UC 4.87013
550 3S5W FAD 4.87013
551 1PZG A3D 4.87013
552 3QOX SAH 4.87013
553 4PLT OXM 4.87013
554 5F8F SFG 4.87013
555 5K7U SAM 4.87013
556 4PLT NAI 4.87013
557 6C4T NA7 4.87013
558 1NVM NAD 4.87013
559 5W7M SAH 4.87013
560 2JBH 5GP 4.88889
561 3QDW A2G 4.8951
562 5Z2L NDP 4.89796
563 1HDR NAD 4.91803
564 2W58 ADP 4.9505
565 5IL1 SAM 5
566 1XCL SAH 5.10638
567 3CBG SAH 5.17241
568 2XYQ SAH 5.17241
569 3B1F NAD 5.17241
570 2F5Z FAD 5.19481
571 3LAD FAD 5.19481
572 3AXB PRO 5.19481
573 3AXB FAD 5.19481
574 2RGO FAD 5.19481
575 4D7E FAD 5.19481
576 2B9W FAD 5.19481
577 5JCA FAD 5.19481
578 5JCA NDP 5.19481
579 4X9M FAD 5.19481
580 1U2Z SAH 5.19481
581 2RGH FAD 5.19481
582 1GTE FAD 5.19481
583 4EUE NAI 5.19481
584 2ZXI FAD 5.19481
585 1E3I CXF 5.19481
586 2JHF NAD 5.19481
587 2PX8 SAH 5.20446
588 2DT5 NAD 5.21327
589 5DLY 5D7 5.26316
590 5DLY SAH 5.26316
591 5GWX SAM 5.28169
592 5GWX SAR 5.28169
593 5ZZ6 ADP 5.28846
594 5ZZ6 NAD 5.28846
595 2AE2 NAP 5.38462
596 2AE2 PTO 5.38462
597 1X1T NAD 5.38462
598 1O5O U5P 5.42986
599 1D4O NAP 5.43478
600 3BXO SAM 5.43933
601 4XUC SAM 5.50459
602 4XUC 43G 5.50459
603 3SQP FAD 5.51948
604 5E9W SAH 5.51948
605 6ER9 FAD 5.51948
606 6ER9 NAP 5.51948
607 5KOK SAH 5.51948
608 4C4A SAH 5.51948
609 5K0A FAD 5.51948
610 4B63 FAD 5.51948
611 4B63 NAP 5.51948
612 4B63 ORN 5.51948
613 5KOK S9T 5.51948
614 3X0V FAD 5.51948
615 4CNK FAD 5.51948
616 6GKV SAH 5.51948
617 1UXG FUM 5.51948
618 1UXG NAD 5.51948
619 4PLG OXM 5.51948
620 4PLG NAI 5.51948
621 5KOK R9T 5.51948
622 5TUF TDC 5.51948
623 2WET FAD 5.51948
624 5TOW NAI 5.51948
625 5TOW ADN 5.51948
626 5TUF FAD 5.51948
627 4KGD FAD 5.51948
628 3IIJ ADP 5.55556
629 2O07 SPD 5.59211
630 2O07 MTA 5.59211
631 4GUS FAD 5.64516
632 4HSU FAD 5.64516
633 4GUT FAD 5.64516
634 1DQN IMU 5.65217
635 5E5U MLI 5.68182
636 2F1K NAP 5.73477
637 1ZK7 FAD 5.78158
638 3EVG SAH 5.81818
639 1SQF SAM 5.84416
640 5JJR SAH 5.84416
641 3K7M FAD 5.84416
642 3CGB FAD 5.84416
643 2ZJ1 ARJ 5.84416
644 4OPC FDA 5.84416
645 4OPC PGT 5.84416
646 2ZJ1 NAD 5.84416
647 2Q1W NAD 5.84416
648 1MV8 NAD 5.84416
649 1KYZ SAH 5.84416
650 1MUU NAD 5.84416
651 2VHW NAI 5.84416
652 3FWN ATR 5.84416
653 1X7D ORN 5.84416
654 1X7D NAD 5.84416
655 1E5Q NDP 5.84416
656 1GZ4 ATP 5.84416
657 1UDB UFG 5.84416
658 1UDB NAD 5.84416
659 1KYZ FER 5.84416
660 1NM5 NAP 5.91133
661 1NM5 NAD 5.91133
662 3DXY SAM 5.9633
663 1QK3 5GP 6.00858
664 1P1C SAH 6.03015
665 3U4C NDP 6.04982
666 2ZIF SAM 6.06061
667 4KWI NAP 6.08365
668 4KWI 1TJ 6.08365
669 2RH4 EMO 6.13718
670 1SQL GUN 6.16438
671 5ERG SAM 6.16883
672 1MO9 FAD 6.16883
673 4KRG SAH 6.16883
674 2EJU SAH 6.16883
675 1MO9 KPC 6.16883
676 2XVE FAD 6.16883
677 3CGD COA 6.16883
678 2XVF FAD 6.16883
679 3CGD FAD 6.16883
680 3CGD NAD 6.16883
681 3AD8 NAD 6.16883
682 3AD8 FAD 6.16883
683 3AD8 PYC 6.16883
684 1GPE FAD 6.16883
685 3TWO NDP 6.16883
686 1CF2 NAP 6.16883
687 2Q28 ADP 6.16883
688 6CEP NAD 6.16883
689 9LDB NAD 6.16883
690 9LDT NAD 6.16883
691 2WMC MGP 6.17978
692 1JA9 NDP 6.20438
693 3GDH SAH 6.22407
694 5E1M SAH 6.22407
695 5E1M PRO PRO LYS ARG ILE ALA 6.22407
696 1AE1 NAP 6.22711
697 4GKV NAD 6.25
698 2NXE SAM 6.29921
699 5UFN SAH 6.30252
700 5YJF 8WO 6.33803
701 5YJF SAH 6.33803
702 2WK1 SAH 6.38298
703 3H2B SAH 6.40394
704 2A14 SAH 6.46388
705 3LN9 FLC 6.47482
706 1ZEM NAD 6.48855
707 1DL5 SAH 6.49351
708 6D6Y SAH 6.49351
709 2IVD FAD 6.49351
710 2FK8 SAM 6.49351
711 2DKH FAD 6.49351
712 2DKH 3HB 6.49351
713 5JWC FAD 6.49351
714 3GGO NAI 6.49351
715 3GGO ENO 6.49351
716 4KOA NDP 6.49351
717 1V2F HCI 6.49351
718 4IWN GEK 6.55022
719 4B4U NAP 6.60066
720 1WG8 SAM 6.66667
721 5N6C NAD 6.66667
722 1PNO NAP 6.66667
723 4D42 W0I 6.73759
724 4D42 NAP 6.73759
725 2Z3Y F2N 6.81818
726 2IXB NAD 6.81818
727 2IXB A2G 6.81818
728 3NJ4 AFX 6.81818
729 5YF1 8V0 6.81818
730 1ZGA SAH 6.81818
731 3NJ4 NAD 6.81818
732 5YF1 SFG 6.81818
733 4YT4 FE9 6.81818
734 1LTH NAD 6.81818
735 5XVH NAP 6.86275
736 3GEG NAD 6.88259
737 2OOR NAD 6.89655
738 2OOR TXP 6.89655
739 1KPG SAH 6.96864
740 4RF2 NAP 6.98529
741 2XMY CDK 7.04698
742 1HGX 5GP 7.10383
743 2G5C NAD 7.11744
744 5NMX FAD 7.14286
745 5GSN NAP 7.14286
746 5GSN FAD 7.14286
747 5NMX NAP 7.14286
748 5GSN MMZ 7.14286
749 5HJM MTA 7.14286
750 5I39 FAD 7.14286
751 4MOP 2H5 7.14286
752 5BRT FAD 7.14286
753 5BRT CH9 7.14286
754 2GMH FAD 7.14286
755 5HXI 5HN 7.14286
756 5HXI FAD 7.14286
757 1ORR NAD 7.14286
758 3BAZ NAP 7.14286
759 2NU8 COA 7.14286
760 2BGM NAJ 7.19424
761 5FEU NAP 7.2165
762 1JG3 ADN 7.23404
763 3HVJ 705 7.23982
764 1TPY SAH 7.31707
765 1Q7B NAP 7.37705
766 4CQM NAP 7.37705
767 5EIN NAP 7.40741
768 2ZFU SAH 7.44186
769 2VDV SAM 7.46753
770 4M73 M72 7.46753
771 1Y8Q ATP 7.46753
772 5WGR FAD 7.46753
773 1E1M NAP 7.46753
774 1E1M FAD 7.46753
775 4M73 SAH 7.46753
776 4DSG FAD 7.46753
777 4DSG UDP 7.46753
778 6ECT SAM 7.46753
779 4PNE SAH 7.46753
780 2PZM NAD 7.46753
781 2PZM UDP 7.46753
782 5Z75 NAD 7.46753
783 5UAO FAD 7.46753
784 6CAM BGC 7.46753
785 3GMB FAD 7.46753
786 2VYN NAD 7.46753
787 1XDS SAM 7.48663
788 5VJN IR8 7.48663
789 5O42 BGC 7.66423
790 5O42 9JW 7.66423
791 5O42 NAD 7.66423
792 4M37 SAH 7.79221
793 1GET NAP 7.79221
794 1GET FAD 7.79221
795 4D04 FAD 7.79221
796 4D04 NAP 7.79221
797 4M38 SAH 7.79221
798 1EFV FAD 7.79221
799 1EFV AMP 7.79221
800 4J36 FAD 7.79221
801 4J36 1HR 7.79221
802 2WHX ADP 7.79221
803 4ITU NAI 7.80669
804 4ITU 1HS 7.80669
805 3MB5 SAM 7.84314
806 1KYQ NAD 8.0292
807 3A4M ADP 8.07692
808 2GAG NAD 8.09524
809 2GAG FAD 8.09524
810 2GAG FOA 8.09524
811 5YJI SAH 8.09859
812 5YJI 8WO 8.09859
813 3AYI FAD 8.11688
814 3AYI HCI 8.11688
815 1REO FAD 8.11688
816 2IID FAD 8.11688
817 2IID PHE 8.11688
818 4LWP SAH 8.11688
819 2R4J 13P 8.11688
820 2R4J FAD 8.11688
821 4XQC 13D 8.11688
822 4XQC NAD 8.11688
823 1RYI GOA 8.11688
824 1RYI FAD 8.11688
825 5L2R MLA 8.11688
826 6GN6 GLC 8.11688
827 3QV1 NAD 8.11688
828 3FUU ADN 8.11808
829 4QM7 GTP 8.18713
830 5KVA SAM 8.27338
831 3UCL NAP 8.44156
832 3UCL CYH 8.44156
833 3UCL FAD 8.44156
834 5VN0 NAI 8.44156
835 5VN0 FAD 8.44156
836 5OC1 FAD 8.44156
837 5XNC MTA 8.44156
838 2Y6Q I7T 8.44156
839 2Y6Q FAD 8.44156
840 1J49 NAD 8.44156
841 4YSX FAD 8.51064
842 3VC1 SAH 8.65385
843 3VC1 GST 8.65385
844 5Z21 NAI 8.65922
845 3LXD FAD 8.6747
846 4JDR FAD 8.76623
847 5MW4 5JU 8.76623
848 5MPT SAH 8.76623
849 2Q7V FAD 8.76623
850 1ZPT FAD 8.88158
851 5OFW 9TW 8.96861
852 3FZG SAM 9
853 5LOG SAH 9.01288
854 4X60 SFG 9.09091
855 4X60 3XV 9.09091
856 4GQB 0XU 9.09091
857 5FA5 MTA 9.09091
858 1KOL NAD 9.09091
859 3LZW FAD 9.09091
860 3LZW NAP 9.09091
861 2FZW NAD 9.09091
862 1D1T NAD 9.09091
863 2ZWA SAH 9.09091
864 3MAG SAH 9.12052
865 1ZQ9 SAM 9.12281
866 3WBF NAP 9.18033
867 3WBF API 9.18033
868 5BSZ SAH 9.2
869 5B4T 3HR 9.23077
870 5B4T NAD 9.23077
871 5FA8 SAM 9.31677
872 1XG5 NAP 9.319
873 2EG5 SAH 9.41558
874 3NYC FAD 9.41558
875 3NYC IAR 9.41558
876 4X7Y SAH 9.41558
877 2NVK FAD 9.41558
878 4IEE AGS 9.41558
879 3CIF NAD 9.41558
880 3CIF G3H 9.41558
881 4YAC NAI 9.42761
882 3MCT SAH 9.42761
883 1N2X SAM 9.63455
884 6BQ6 TER 9.74026
885 5ODQ FAD 9.74026
886 1HKU NAD 9.74026
887 5WP5 SAH 10.0649
888 3GF4 FAD 10.0649
889 3GF4 UPG 10.0649
890 1OC2 NAD 10.0649
891 1OC2 TDX 10.0649
892 3KB6 NAD 10.0649
893 3VPH OXM 10.0649
894 3VPH NAD 10.0649
895 1KPH SAH 10.1045
896 3C3Y SAH 10.1266
897 1R18 SAH 10.1322
898 1E6E FAD 10.1562
899 5N53 8NB 10.2564
900 3PFG TLO 10.2662
901 3PFG SAM 10.2662
902 1Q1R FAD 10.3896
903 1H2B NAJ 10.3896
904 3V1Y NAD 10.3896
905 5ULP KB1 10.4478
906 4FK7 P34 10.4803
907 5TDC NMM ILE PHE SER 10.5263
908 2DPM SAM 10.5634
909 5N5D SAM 10.6195
910 1COY FAD 10.7143
911 1COY AND 10.7143
912 1WOG 16D 10.8197
913 4BV6 FAD 11.039
914 1I8T FAD 11.039
915 1U3U BNF 11.039
916 1U3U NAD 11.039
917 1JJ7 ADP 11.1538
918 1UAY ADN 11.157
919 1JNR FAD 11.3636
920 1J5P NAD 11.4625
921 3NKS FAD 11.6883
922 6DEN TP9 11.6883
923 6DEN FAD 11.6883
924 6DEN G8A 11.6883
925 3QWI CUE 11.8519
926 3QWI NAP 11.8519
927 3WDM ADN 11.8774
928 1YQZ FAD 12.013
929 1T9D FAD 12.013
930 1T9D P25 12.013
931 1T9D 1MM 12.013
932 1T9D PYD 12.013
933 5WKC FAD 12.013
934 5DF1 58X 12.013
935 5DF1 NAP 12.013
936 1M2K APR 12.0482
937 5JE8 NAD 12.2517
938 4YMH SAH 12.5
939 6FLZ MMA 12.5
940 1DCP HBI 12.5
941 1JJV ATP 12.6214
942 6BII NAP 12.6623
943 4A6D SAM 12.6623
944 4J4H NAI 12.7413
945 4J4H 1J1 12.7413
946 4JK3 NAD 12.7413
947 1ZBQ NAD 12.844
948 3HB5 NAP 12.987
949 2HK9 ATR 13.0909
950 4J56 FAD 13.1579
951 4E5N NAD 13.6364
952 3A4T SFG 13.8686
953 2CDU FAD 14.2857
954 2CDU ADP 14.2857
955 3CMC NAD 14.2857
956 4J7U YTZ 14.5833
957 4J7U NAP 14.5833
958 6C4N NAP 14.6104
959 5AOV NAP 14.6104
960 6F5Z SAH 14.7541
961 1L3I SAH 15.1042
962 3GD4 NAD 15.2597
963 3GD4 FAD 15.2597
964 5CUQ NSC 15.3558
965 3COB ADP 15.5844
966 2PK3 A2R 15.9091
967 1IM8 SAI 15.9836
968 4II2 ATP 18.0723
969 1DJN ADP 18.1818
970 1O94 ADP 18.1818
971 5L95 AMP 18.75
972 5E8J SAH 20.4545
973 2PT9 S4M 20.7792
974 2PT9 2MH 20.7792
975 2CDN ADP 20.8955
976 1EDO NAP 21.7213
977 5YEC ATP 22.6891
978 2I7C AAT 22.9682
979 4QTU SAM 23.0769
980 4KXQ APR 30
981 3RNM FAD 39.6552
Pocket No.: 2; Query (leader) PDB : 3VYW; Ligand: SAM; Similar sites found with APoc: 48
This union binding pocket(no: 2) in the query (biounit: 3vyw.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 1C4Q GLA GAL BGC None
2 5C9P FUC None
3 4WZ6 ATP 1.72414
4 1PL6 NAD 1.94805
5 1Z03 OCH 1.94805
6 6A0S NDP 1.94805
7 6A0S HSE 1.94805
8 3LST SAH 2.5974
9 5SWI BMA 2.92208
10 5YAP 8S0 2.92208
11 1D8C SOR 3.24675
12 3TN7 NJP 3.50195
13 4TQK NAG 3.57143
14 2VVG ADP 3.57143
15 5U5G NAP 3.72881
16 1FWV SGA MAG FUC 3.73134
17 1I7M