Receptor
PDB id Resolution Class Description Source Keywords
3WXM 2.3 Å EC: 3.1.-.- CRYSTAL STRUCTURE OF ARCHAEAL PELOTA AND GTP-BOUND EF1 ALPHA AEROPYRUM PERNIX K1 MRNA SURVEILLANCE RIBOSOME TRANSLATION-HYDROLASE COMPLEX
Ref.: STRUCTURAL BASIS FOR MRNA SURVEILLANCE BY ARCHAEAL AND GTP-BOUND EF1 ALPHA COMPLEX PROC.NATL.ACAD.SCI.USA V. 107 17575 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG A:502;
C:502;
G:502;
E:502;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
GTP A:501;
G:501;
C:501;
E:501;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
523.18 C10 H16 N5 O14 P3 c1nc2...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3WXM 2.3 Å EC: 3.1.-.- CRYSTAL STRUCTURE OF ARCHAEAL PELOTA AND GTP-BOUND EF1 ALPHA AEROPYRUM PERNIX K1 MRNA SURVEILLANCE RIBOSOME TRANSLATION-HYDROLASE COMPLEX
Ref.: STRUCTURAL BASIS FOR MRNA SURVEILLANCE BY ARCHAEAL AND GTP-BOUND EF1 ALPHA COMPLEX PROC.NATL.ACAD.SCI.USA V. 107 17575 2010
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 18 families.
1 3WXM - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 16 families.
1 3WXM - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 15 families.
1 3WXM - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GTP; Similar ligands found: 147
No: Ligand ECFP6 Tc MDL keys Tc
1 GTP 1 1
2 GP3 0.921053 0.973684
3 GDP 0.909091 1
4 GSP 0.853659 0.948718
5 GNH 0.82716 0.986667
6 G1R 0.819277 0.986667
7 GAV 0.811765 0.961039
8 GNP 0.809524 0.973684
9 GCP 0.797619 0.973684
10 5GP 0.797468 0.986486
11 G 0.797468 0.986486
12 GMV 0.764706 0.973684
13 G2R 0.764045 0.961039
14 G5P 0.755319 0.973684
15 GTG 0.752688 0.936709
16 G2P 0.747126 0.961039
17 G3A 0.744681 0.973684
18 GDD 0.741935 0.961039
19 GKE 0.741935 0.961039
20 GDC 0.741935 0.961039
21 0O2 0.736264 0.986486
22 GP2 0.729412 0.961039
23 6CK 0.726316 0.936709
24 Y9Z 0.723404 0.902439
25 GPG 0.717391 0.961039
26 GFB 0.715789 0.961039
27 GDR 0.715789 0.961039
28 GDP MG 0.712644 0.923077
29 GDP BEF 0.704545 0.9
30 GPD 0.704082 0.925
31 JB2 0.693878 0.961039
32 GKD 0.693878 0.961039
33 GCP G 0.692308 0.935065
34 GDX 0.686869 0.973684
35 ALF 5GP 0.685393 0.888889
36 GTP MG 0.681319 0.923077
37 BEF GDP 0.681319 0.888889
38 GH3 0.681319 0.973333
39 YGP 0.677083 0.901235
40 G3D 0.67033 0.986486
41 GDP AF3 0.659574 0.888889
42 GDP ALF 0.659574 0.888889
43 DGT 0.659341 0.923077
44 GMP 0.658228 0.88
45 G4P 0.655914 0.986486
46 JB3 0.653846 0.948718
47 NGD 0.647619 0.961039
48 CAG 0.642202 0.880952
49 2MD 0.62963 0.891566
50 G G 0.622449 0.935065
51 MGP 0.619565 0.961039
52 U2G 0.616822 0.936709
53 6G0 0.612903 0.961039
54 MGD 0.612613 0.891566
55 TPG 0.608696 0.840909
56 CG2 0.605505 0.936709
57 GDP 7MG 0.601942 0.911392
58 FEG 0.601852 0.879518
59 ZGP 0.59633 0.869048
60 MD1 0.591304 0.891566
61 PGD 0.591304 0.925
62 3GP 0.590909 0.946667
63 GPX 0.581633 0.946667
64 DGI 0.580645 0.923077
65 IDP 0.576087 0.972973
66 DBG 0.567797 0.948718
67 FE9 0.555556 0.776596
68 2GP 0.555556 0.96
69 G4M 0.547619 0.880952
70 BGO 0.544643 0.924051
71 I2C FE2 CMO CMO 0.538462 0.808989
72 ATP 0.537634 0.92
73 G1G 0.533898 0.925
74 AQP 0.531915 0.92
75 5FA 0.531915 0.92
76 G A A A 0.525862 0.923077
77 U A G G 0.521368 0.935065
78 01G 0.518868 0.902439
79 ITT 0.510638 0.868421
80 P2G 0.510638 0.883117
81 GGM 0.504274 0.901235
82 G1R G1R 0.504065 0.924051
83 DGP 0.5 0.910256
84 PGD O 0.5 0.850575
85 MGO 0.5 0.864198
86 P1G 0.5 0.871795
87 DG 0.5 0.910256
88 GTA 0.495495 0.936709
89 B4P 0.489362 0.894737
90 AP5 0.489362 0.894737
91 IMP 0.489362 0.959459
92 7DT 0.484536 0.906667
93 G G U 0.482143 0.935065
94 GPC 0.479339 0.879518
95 G C 0.478992 0.9
96 BA3 0.478723 0.894737
97 ADP 0.473684 0.92
98 G2Q 0.471698 0.961039
99 G7M 0.46875 0.948052
100 25L 0.458716 0.907895
101 A2D 0.457447 0.894737
102 RGT 0.45045 0.909091
103 AGS 0.45 0.873418
104 SAP 0.45 0.873418
105 SGP 0.44898 0.82716
106 U G A 0.448529 0.888889
107 A4P 0.445378 0.869048
108 G G G RPC 0.442623 0.875
109 ACQ 0.441176 0.896104
110 ANP 0.441176 0.896104
111 8GT 0.441176 0.875
112 APC G U 0.44 0.886076
113 G U34 0.438017 0.888889
114 6AD 0.436893 0.841463
115 G G G C 0.433071 0.9125
116 UP5 0.432203 0.873418
117 35G 0.431373 0.933333
118 C2E 0.431373 0.921053
119 PCG 0.431373 0.933333
120 A G C C 0.429688 0.911392
121 5GP 5GP 0.427184 0.883117
122 TAT 0.427184 0.884615
123 APR 0.425743 0.894737
124 AR6 0.425743 0.894737
125 AN2 0.424242 0.907895
126 7DD 0.424242 0.906667
127 DG DG 0.423423 0.865854
128 AD9 0.421569 0.896104
129 M33 0.42 0.883117
130 7D4 0.42 0.835443
131 UCG 0.419847 0.911392
132 H6Y 0.419048 0.946667
133 G C C C 0.416667 0.924051
134 ACP 0.415842 0.896104
135 T5A 0.414634 0.802326
136 MGQ 0.412844 0.935897
137 ADQ 0.412844 0.871795
138 A1R 0.412844 0.839506
139 MGT 0.411215 0.823529
140 A G U 0.410072 0.888889
141 93A 0.41 0.833333
142 A22 0.407407 0.907895
143 CA0 0.405941 0.896104
144 ATF 0.40566 0.884615
145 AGO 0.404762 0.888889
146 MGV 0.401786 0.890244
147 CGP 0.4 0.86747
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3WXM; Ligand: GTP; Similar sites found: 531
This union binding pocket(no: 1) in the query (biounit: 3wxm.bio2) has 26 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4IDN GNP 0.00003688 0.49892 1.59574
2 4A4Z ANP 0.00248 0.45024 2.12766
3 1TQ4 GDP 0.0000003966 0.58914 2.17918
4 1XP8 AGS 0.0001172 0.52252 2.18579
5 1V8K ANP 0.000004013 0.58815 2.19512
6 2XT3 ADP 0.000005017 0.61243 2.32558
7 4IOK XPO 0.001521 0.42347 2.39362
8 4IOK ADP 0.001928 0.40646 2.39362
9 1PSC EBP 0.004037 0.42072 2.46575
10 1F9V ADP 0.00002366 0.5715 2.59366
11 5I0H ADP BEF 0.00000131 0.5667 2.65957
12 2XAU ADP 0.001224 0.45535 2.68456
13 1YTM ATP 0.0004994 0.45507 2.68456
14 2OWZ CIT 0.00547 0.44494 2.71084
15 3ZFD ANP 0.0000003665 0.62142 2.849
16 1R6B ADP 0.000324 0.48808 2.92553
17 1IHU ADP 0.0003925 0.45134 2.92553
18 1IHU AF3 0.0006116 0.44722 2.92553
19 1G3Q ADP 0.0002181 0.49637 2.95359
20 2PL3 ADP 0.001797 0.46245 2.9661
21 5CK5 GDP 0.00000007201 0.6852 3.16456
22 3GJ3 GDP 0.0000000004458 0.78351 3.16742
23 3GJ0 GDP 0.000000000857 0.76948 3.16742
24 5K5Z ANP 0.0005869 0.44035 3.18471
25 4LYA ATP 0.000102 0.51229 3.19149
26 2DPY ADP 0.001804 0.46803 3.19149
27 2Y65 ADP 0.000005434 0.40627 3.28767
28 3BOS CDP 0.00009652 0.51991 3.30579
29 4AG5 ADP 0.00004255 0.55772 3.31633
30 1JI0 ATP 0.00009526 0.53446 3.33333
31 4IV9 TSR 0.03457 0.40726 3.3557
32 3MD0 GDP 0.0000000005675 0.79174 3.38028
33 4WZ6 ATP 0.00003557 0.56337 3.44828
34 5I34 GDP 0.00009347 0.51412 3.45745
35 5LTJ ADP 0.0002369 0.49464 3.45745
36 3TBK ANP 0.004014 0.44995 3.45745
37 5LTJ BEF 0.01344 0.42738 3.45745
38 2W58 ADP 0.000009864 0.60477 3.46535
39 3COB ADP 0.00000392 0.61657 3.52304
40 1LVG ADP 0.000009799 0.5858 3.53535
41 2Q2Y ADP 0.002692 0.4275 3.54223
42 2Q2Y MKR 0.002945 0.42475 3.54223
43 2ZFI ADP 0.00005121 0.53352 3.55191
44 2IS6 ADP 0.0006492 0.47901 3.57942
45 1P4V GLY 0.007437 0.43777 3.57942
46 2D2F ADP 0.0002532 0.52631 3.6
47 3FVQ ATP 0.0007759 0.4468 3.62117
48 1YQT ADP 0.0001762 0.52556 3.7234
49 1F5N GNP 0.00000982 0.49953 3.7234
50 3FKQ ATP 0.0001417 0.4886 3.75335
51 3EZ2 ADP 0.0006722 0.4841 3.76884
52 1M7G AV2 0.000006145 0.58738 3.79147
53 1M7G ADP 0.000825 0.41256 3.79147
54 1M7G ADX 0.0006844 0.40495 3.79147
55 1NY5 ADP 0.004117 0.42258 3.80313
56 4D81 ADP 0.00123 0.45065 3.88693
57 1G6H ADP 0.000007771 0.60937 3.89105
58 3B7G ANP 0.002121 0.44871 3.91304
59 3LRE ADP 0.000004789 0.61374 3.94366
60 1WA5 GTP 0.00000000021 0.63073 3.97727
61 5L3V GDP 0.00001928 0.54032 4.01338
62 4L80 OXL 0.01929 0.41671 4.02299
63 5HR5 ADP 0.0008379 0.45379 4.02685
64 3QDK QDK 0.01037 0.43701 4.02685
65 5LB3 ADP 0.0004419 0.49333 4.04494
66 3GJ4 GDP 0.000000000862 0.76936 4.0724
67 3GJ5 GDP 0.0000000006267 0.76365 4.0724
68 3QXC ATP 0.001201 0.41878 4.13223
69 2OG2 MLI 0.0001137 0.52227 4.17827
70 1B0U ATP 0.002385 0.43738 4.19847
71 3GJX GTP 0.0000000001975 0.69891 4.25056
72 5KSZ GCP 0.000001422 0.59368 4.25056
73 4H1V GNP 0.000004348 0.55682 4.25056
74 1PUJ GNP 0.0000000005336 0.74384 4.25532
75 1JWY GDP 0.00000153 0.58452 4.25532
76 1JWY ADP 0.00002787 0.53947 4.25532
77 2FAH GDP 0.0005096 0.46828 4.25532
78 4UOX PUT 0.01127 0.40622 4.28266
79 2PZE ATP 0.00001202 0.59457 4.36681
80 1JJV ATP 0.0001342 0.53115 4.36893
81 3BFV ADP 0.00009669 0.51988 4.42804
82 3VX3 ADP 0.000958 0.4469 4.43548
83 4GOX A3P 0.00386 0.41005 4.47284
84 1U0J ADP 0.001431 0.46748 4.49438
85 1S8F GDP 0.00000001811 0.59518 4.51977
86 4IHQ ADP 0.0005293 0.48936 4.52128
87 4OHY ANP 0.0001841 0.46088 4.52128
88 2FSH ANP 0.007291 0.43159 4.52128
89 4YS0 ADP 0.003494 0.4258 4.52128
90 4PPF FLC 0.000003589 0.62264 4.57143
91 5HCN GCP 0.00000004118 0.67599 4.5977
92 4MKF AP5 0.005047 0.41695 4.60829
93 3DC4 ADP 0.00004053 0.55375 4.65116
94 3QKT ANP 0.002495 0.4147 4.71976
95 1M2O GNP 0.0000000001561 0.69985 4.73684
96 1BO4 COA 0.01651 0.40942 4.7619
97 5GOE GDP 0.000000009851 0.69544 4.78723
98 1XKV ATP 0.0003418 0.48147 4.78723
99 3CV2 OXL 0.005196 0.44937 4.78723
100 2C9O ADP 0.000862 0.44482 4.78723
101 1SVK ALF GDP 0.000000001152 0.61805 4.81586
102 1W5T ANP 0.00257 0.42429 4.85437
103 1W5T ADP 0.004242 0.422 4.85437
104 1IBR GNP 0.0000000001323 0.68821 4.9217
105 3B9Q MLI 0.000104 0.52735 4.96689
106 2RCN GDP 0.00000001114 0.71445 5.02793
107 1RYH GNP 0.000000002809 0.72111 5.05319
108 2WKQ GTP 0.000000003678 0.66033 5.05319
109 4V03 ADP 0.0001088 0.5049 5.05837
110 4RZ3 ADP 0.0004053 0.46801 5.08475
111 2VVG ADP 0.000001581 0.64291 5.14286
112 5GJC ATP 0.00004066 0.53846 5.14541
113 5XDR ADP 0.001296 0.45904 5.14541
114 3TK1 GDP 0.000000001062 0.79194 5.15152
115 2OBM ADP 0.002449 0.46799 5.18732
116 1SQ5 ADP 0.0002363 0.4947 5.19481
117 2OM2 GDP 0.0000001959 0.60239 5.23077
118 1XX6 ADP 0.001186 0.46608 5.2356
119 2GDJ ANP 0.0002321 0.50109 5.30303
120 4IEE AGS 0.00124 0.47063 5.31915
121 1D8C GLV 0.003762 0.4404 5.31915
122 1P7T PYR 0.006729 0.43898 5.31915
123 1ION ADP 0.00007727 0.51191 5.34979
124 1MH1 GNP 0.000000005087 0.62696 5.37634
125 4HDO GNP 0.0000000001701 0.68376 5.38922
126 3X1Z GNP 0.0000000002076 0.66705 5.38922
127 1IN4 ADP 0.001345 0.44039 5.38922
128 1BH2 GSP 0.000000001206 0.62834 5.39683
129 2X7I CIT 0.009339 0.42172 5.51948
130 1FZQ GDP 0.0000000001547 0.80622 5.52486
131 2G77 GDP 0.000000002126 0.70609 5.55556
132 1TAD ALF 0.000000001008 0.63106 5.55556
133 1TAD GDP 0.000000001008 0.63106 5.55556
134 2G77 AF3 0.000001915 0.62927 5.55556
135 4TTQ ATP 0.0001589 0.50921 5.5814
136 4R43 GDP 0.0004552 0.48663 5.58511
137 3RC3 ANP 0.003956 0.44508 5.58511
138 2Y8E GNP 0.00000000008734 0.70994 5.58659
139 1OYY AGS 0.005741 0.4322 5.59284
140 2FJU GSP 0.0000000003276 0.72246 5.61798
141 4P32 ADP 0.004466 0.41058 5.62249
142 2IYL GDP 0.00004459 0.53649 5.6338
143 4QOS ADP 0.003443 0.43416 5.66038
144 5E5U MLI 0.005525 0.42343 5.68182
145 1NRJ GTP 0.000000003308 0.67903 5.6962
146 1KO8 6PG 0.002417 0.42914 5.71429
147 5JCP GDP ALF 0.000000003895 0.69423 5.72792
148 1Z0A GDP 0.00000000375 0.7152 5.74713
149 3TNF GNP 0.0000000001065 0.67802 5.74713
150 4LHW GNP 0.0000000007477 0.67263 5.74713
151 1A4R GNH 0.00000001613 0.6664 5.75916
152 1A4R GDP 0.0000000213 0.65231 5.75916
153 5KSP GDP 0.0000004809 0.62451 5.78947
154 1VG8 GNP 0.0000000000396 0.70841 5.7971
155 1VG0 GDP 0.00000002051 0.55259 5.7971
156 1Z06 GNP 0.0000000000598 0.72542 5.82011
157 4DSU GDP 0.00000001093 0.614 5.82011
158 5IRR GSP 0.00000008856 0.60994 5.84416
159 4HSE ADP 0.0005444 0.47721 5.85106
160 5IFS ADP 0.0006936 0.46699 5.85106
161 2FNA ADP 0.0009276 0.43955 5.88235
162 2CBZ ATP 0.00000408 0.6235 5.90717
163 1HE1 GDP 0.000000344 0.59181 5.92593
164 1HE1 AF3 0.0001402 0.52573 5.92593
165 1H65 GDP 0.0002249 0.46563 5.92593
166 4FRZ ADP 0.00002761 0.56799 5.95855
167 1W7J ADP BEF 0.00003912 0.5138 5.96026
168 1AZT GSP 0.0000000004783 0.64289 5.97015
169 1FWV SGA MAG FUC 0.005594 0.44773 5.97015
170 1Y63 ADP 0.00006304 0.52905 5.97826
171 1KY3 GDP 0.000000005886 0.6958 6.04396
172 4OI4 ATP 0.001005 0.43436 6.08696
173 2B8W ALF 5GP 0.000006796 0.5193 6.09756
174 5M04 GDP 0.000000000245 0.81022 6.11111
175 2NCD ADP 0.00003143 0.5649 6.11702
176 3GJ7 GDP 0.0000000006169 0.77654 6.12245
177 4WEI GLC GAL 0.005765 0.44697 6.13718
178 4U00 ADP 0.00001326 0.59797 6.14754
179 3PCR GTP 0.0000000003372 0.70345 6.17284
180 4LJ9 ACP 0.003652 0.44192 6.19469
181 1K6M AGS 0.002661 0.41678 6.25
182 3RWO GDP 0.00000003363 0.60649 6.26398
183 2ODE ALF GDP 0.0000000006917 0.63692 6.28571
184 1WF3 GNP 0.0000000006505 0.66126 6.31229
185 5J1J ANP 0.00006267 0.48446 6.31579
186 1XPJ TLA 0.0278 0.41654 6.34921
187 3FWY ADP 0.00005495 0.50715 6.36943
188 2OZE AGS 0.0005457 0.4577 6.37584
189 1P9B GDP 0.0001834 0.48355 6.38298
190 1P9B HDA 0.01997 0.41576 6.38298
191 4QDI ATP 0.01857 0.40309 6.38298
192 5XCO GDP 0.0000000105 0.68421 6.43275
193 5WDR GNP 0.0000000002802 0.67568 6.43275
194 1VG1 GDP 0.000000002077 0.73855 6.48649
195 1VG9 GDP 0.000000004024 0.55349 6.48649
196 4PX9 ADP 0.001946 0.4607 6.50685
197 3RAB GNP 0.00000000008135 0.71118 6.50888
198 2ZEJ GDP 0.000005287 0.50993 6.52174
199 3DZD ADP 0.002564 0.43593 6.52174
200 3Q9L ATP 0.00005308 0.50782 6.53846
201 4XFR CIT 0.02383 0.40454 6.55738
202 3B5J 12D 0.00007707 0.53924 6.58436
203 2ZR9 DTP 0.0001095 0.51721 6.59026
204 2J0V GDP 0.0000001447 0.50272 6.60377
205 1NVV GNP 0.0000000001073 0.69151 6.62651
206 1NVU GTP 0.0000000006224 0.66217 6.62651
207 1WQ1 AF3 0.000002218 0.63022 6.62651
208 1WQ1 GDP 0.00000006148 0.60949 6.62651
209 1CLU DBG 0.00000005961 0.47855 6.62651
210 2EFE GNH 0.00000009582 0.63997 6.62983
211 4LPS GDP 0.0000006662 0.61768 6.64894
212 5VGR GDP 0.000576 0.46113 6.64894
213 4XGU ADP 0.0006256 0.45951 6.64894
214 2ZJ5 ADP 0.01536 0.42217 6.64894
215 4LX0 BEF GDP 0.0000000001087 0.69143 6.71141
216 1OIV GDP 0.00000007799 0.59187 6.71141
217 1Z6T ADP 0.0008765 0.45291 6.71141
218 3CPJ GDP 0.00000002872 0.66408 6.72646
219 2A5F GTP 0.0000000002424 0.70064 6.73575
220 4FCW ADP 0.001482 0.45623 6.75241
221 3N5C GDP 0.000000001506 0.75738 6.79012
222 5MVR ADP 0.00005834 0.53072 6.79012
223 2WMO GTP 0.000000001776 0.7305 6.84211
224 2QEN ADP 0.0002747 0.47563 6.85714
225 3W5J GDP 0.0000002966 0.67568 6.86275
226 1OW3 GDP 0.00000009097 0.5391 6.91489
227 1YZN GNP 0.00000000009758 0.69319 6.93512
228 5TAR GDP 0.00000002993 0.66325 6.93512
229 2BCG GDP 0.00000006915 0.62973 6.93512
230 1FNN ADP 0.001732 0.43554 6.94087
231 2GJ8 ALF GDP 0.0000000004077 0.66897 6.97674
232 2BEK ATP 0.0002712 0.46219 7.00389
233 2VF7 ADP 0.0009059 0.46654 7.00713
234 1XMV ADP 0.00009468 0.51385 7.02247
235 3LXR GDP 0.000000288 0.62636 7.02703
236 4D0N GDP 0.00000007783 0.50205 7.02703
237 1KMQ GNP 0.0000000005188 0.69568 7.06522
238 2AWN ADP 0.000004035 0.63193 7.08661
239 1I4D GDP 0.00000003913 0.69861 7.14286
240 2WHX ADP 0.00001444 0.58388 7.18085
241 2JLR ANP 0.0001235 0.49665 7.18085
242 1KK8 BEF ADP 0.00002853 0.51998 7.19424
243 1NJF AGS 0.0003956 0.42885 7.2
244 1NJF ADP 0.0006262 0.41126 7.2
245 5XQL C2E 0.04096 0.40887 7.2165
246 4XOI GTP 0.00000000114 0.67322 7.22222
247 3T34 GDP 0.00002168 0.50362 7.22222
248 1L2T ATP 0.002078 0.41795 7.23404
249 1Z0F GDP 0.000000001586 0.7442 7.26257
250 1G6O ADP 0.0004979 0.47377 7.27273
251 5L3R GCP 0.000003885 0.5292 7.30897
252 1G4U GDP 0.0000008883 0.58079 7.31071
253 1G4U AF3 0.0004118 0.50208 7.31071
254 5MZN ADP 0.003406 0.45367 7.44681
255 5H67 ATP 0.01655 0.40552 7.44681
256 2CHG ANP 0.001245 0.44603 7.52212
257 4K81 GTP 0.0000000013 0.63748 7.60234
258 1M7B GTP 0.000000002047 0.68805 7.6087
259 1G16 GDP 0.00000004342 0.62307 7.64706
260 1GOT GDP 0.0000002481 0.59098 7.64706
261 5KDO GDP 0.0000004415 0.58713 7.64706
262 1GP2 GDP 0.000001084 0.55769 7.64706
263 1B7T ADP 0.0001384 0.49998 7.69231
264 5JCZ GDP 0.000000005288 0.67902 7.71277
265 4PJ3 ANP 0.007529 0.41432 7.71277
266 4KVG GTP 0.0000000002357 0.69269 7.7381
267 3IIJ ADP 0.00009382 0.52052 7.77778
268 1YZG GDP 0.000000002752 0.73266 7.82123
269 2WIC GNP 0.000000005394 0.71856 7.86517
270 2HF9 GSP 0.0000006787 0.59318 7.9646
271 1YRB GDP 0.000000005604 0.69678 8.01527
272 1ZJ6 G3D 0.000000002327 0.73617 8.02139
273 1D5C GDP 0.00000002782 0.65573 8.02469
274 3FIU POP 0.03534 0.40209 8.03213
275 2C04 GCP 0.00006537 0.50374 8.08081
276 4R98 GNH 0.0000001162 0.66415 8.11808
277 2QTV GNP 0.0000000002588 0.69947 8.16327
278 2FFQ GSP 0.00000000003858 0.72745 8.18713
279 3PQC GDP 0.0000002062 0.63319 8.20513
280 2VB6 ADP BEF 0.000107 0.47481 8.24468
281 4PFO ADP 0.0002848 0.44932 8.24468
282 3KJI ADP 0.0002477 0.48272 8.26772
283 1T5C ADP 0.000004474 0.61803 8.2774
284 5TSH ANP 0.0001677 0.50807 8.2774
285 5TSH ADP 0.0005665 0.49709 8.2774
286 4E3Q PMP 0.006403 0.42985 8.2774
287 3Q85 GNP 0.000000000317 0.79082 8.28402
288 4YMU ATP 0.0001191 0.52218 8.33333
289 5BQ5 ADP BEF 0.0008286 0.46334 8.46561
290 1CS4 GSP 0.0000000005477 0.65251 8.49057
291 5FTB ANP 0.0005555 0.47153 8.51064
292 5FHD ADP ALF 0.0003941 0.45952 8.51064
293 5GVR LMR 0.002324 0.44013 8.54701
294 4R2I ANP 0.001049 0.48028 8.57143
295 1FP6 ADP 0.0001852 0.48855 8.65052
296 5BXQ GDP 0.000000001213 0.74981 8.66142
297 5TB5 GDP 0.00000001665 0.6847 8.66667
298 2C5L GTP 0.00000000009858 0.69315 8.67052
299 3EC1 GDP 0.000000005062 0.71989 8.67209
300 4XSH GSP 0.000000007164 0.6732 8.6758
301 3E70 GDP 0.000024 0.5426 8.72483
302 4XTR ADP 0.0005484 0.4576 8.75706
303 2WOJ ADP ALF 0.0001696 0.45187 8.75706
304 4XTR ATP 0.000559 0.44496 8.75706
305 4XVU ATP 0.0006207 0.44307 8.75706
306 2QZ4 ADP 0.0005019 0.47361 8.77863
307 3T5G GDP 0.00000000438 0.56028 8.83978
308 3H4S ADP 0.000007895 0.40042 8.88889
309 4U5X GNP 0.000000002762 0.69147 8.98876
310 3E5H GNP 0.00000000097 0.66811 8.98876
311 5KUT GDP 0.0000003261 0.63264 8.99471
312 1XTQ GDP 0.000000001341 0.67853 9.03955
313 5HPY GDP 0.00000006058 0.6405 9.05172
314 4WZA ADP 0.0000271 0.53258 9.05797
315 4WZA ACP 0.0000271 0.53258 9.05797
316 1UJ2 C5P 0.001837 0.41062 9.12698
317 3CNL GNP 0.000000005583 0.74145 9.16031
318 5M7P ADP 0.002695 0.42706 9.17226
319 3TKL GTP 0.00000000004472 0.73056 9.18367
320 3QBT GNP 0.00000000004552 0.72127 9.28571
321 1TU3 GNP 0.0000000001022 0.70721 9.35672
322 1R2Q GNP 0.0000000001736 0.60292 9.41177
323 4DCT GDP 0.0000000004537 0.77041 9.42982
324 2EW1 GNP 0.00000000003881 0.70265 9.45274
325 3NHB ADP 0.00006175 0.55019 9.47712
326 4ZNL BEF ADP 0.000206 0.49757 9.48905
327 3MJH GTP 0.0000000000722 0.71325 9.52381
328 5N69 ADP 0.00006928 0.50822 9.54774
329 2IXE ATP 0.0008843 0.44043 9.5941
330 2UZI GTP 0.0000000002916 0.68899 9.61539
331 4YDS ATP 0.00009912 0.53356 9.64912
332 2BME GNP 0.000000000054 0.7183 9.67742
333 4DKX GDP 0.0000000007266 0.77302 9.72222
334 1SVI GDP 0.000000005327 0.74248 9.74359
335 4WOP CTP 0.000489 0.45547 9.77778
336 3AQ4 GDP 0.000000004539 0.72218 9.78261
337 5DIF GNP 0.00000000012 0.6897 9.79021
338 5UWW GNP 0.0000000001347 0.68784 9.79021
339 5UWI GNP 0.0000000001376 0.68746 9.79021
340 5UWJ GNP 0.0000000001393 0.68725 9.79021
341 5UWR GNP 0.0000000001443 0.68666 9.79021
342 5DHF GNP 0.000000000146 0.68645 9.79021
343 5UWQ GNP 0.0000000001542 0.68559 9.79021
344 5UWT GNP 0.0000000001572 0.68527 9.79021
345 5UWH GNP 0.0000000001862 0.68244 9.79021
346 5UWP GNP 0.00000000015 0.67227 9.79021
347 5DI9 GNP 0.0000000001973 0.66796 9.79021
348 3RLF ANP 0.001046 0.43364 9.84043
349 1GXU 2HP 0.005891 0.43166 9.89011
350 4KAX GTP 0.0000000000402 0.75163 9.93789
351 1MR3 G3D 0.000000005678 0.71748 9.94475
352 3SFV GDP 0.0000000787 0.55919 9.94475
353 1OIX GDP 0.00000000163 0.65908 9.94764
354 4HAT GNP 0.0000000001193 0.67596 10
355 3UIE ANP 0.0001242 0.50219 10
356 3QF7 ANP 0.002251 0.43051 10
357 1Z2A GDP 0.0000004807 0.57237 10.119
358 5L3W GDP 0.00005553 0.51867 10.1307
359 1Z0J GTP 0.0000000001385 0.68748 10.1695
360 4BQS ADP 0.0002342 0.50089 10.2273
361 1GWN GTP 0.000000001856 0.68988 10.2439
362 3NKV GNP 0.0000000002312 0.69303 10.2857
363 4KFU ACP 0.000006968 0.59968 10.3774
364 1GOJ ADP 0.000001316 0.64829 10.4225
365 1G8S MET 0.0163 0.41754 10.4348
366 2GCO GNP 0.000000001645 0.71111 10.4478
367 2GCN GDP 0.0000001208 0.60423 10.4478
368 5L3S GNP 0.00001216 0.509 10.473
369 5L3S G 0.02363 0.41369 10.473
370 3M1I GTP 0.0000000002583 0.67705 10.5023
371 3WYF GTP 0.0000000004947 0.65352 10.5023
372 4ZI2 GNP 0.000000000003027 0.79924 10.5263
373 3ZS9 ADP ALF 0.0001215 0.45737 10.5263
374 4HI0 GDP 0.000005777 0.53883 10.5528
375 1G41 ADP 0.000591 0.47026 10.5856
376 1APZ ASP 0.02538 0.40807 10.6383
377 1D2N ANP 0.00645 0.40697 10.6383
378 1QHG ATP 0.01474 0.4008 10.6383
379 4KBF AMP 0.008496 0.42821 10.6849
380 3DEF GDP 0.00004592 0.51645 10.687
381 4P4T GDP 0.00000972 0.53492 10.7383
382 1JJ7 ADP 0.000005438 0.62017 10.7692
383 2VWT PYR 0.02031 0.40988 10.8614
384 3GJ8 GDP 0.000000000606 0.76435 10.8696
385 3IO3 ADP 0.0007652 0.45121 10.9195
386 1RE0 GDP 0.0000000004452 0.79708 10.9756
387 1S9D GDP 0.000000006786 0.71375 10.9756
388 2A5J GDP 0.000000004945 0.70954 10.9948
389 5SZH GNP 0.0000000001519 0.68589 11.1111
390 5UQW GDP 0.000000008888 0.63686 11.1111
391 4ZG4 VO4 ADP 0.000003785 0.53512 11.1702
392 4C4P GNP 0.0000000009188 0.67206 11.215
393 2A9K GDP 0.00000006634 0.54277 11.2299
394 2XTZ GSP 0.0000000001508 0.70045 11.2994
395 1KAO GDP 0.00000004382 0.64684 11.3772
396 2CJW GDP 0.000000001888 0.75254 11.4583
397 1VHT BA3 0.001054 0.45841 11.4679
398 3LN9 FLC 0.0127 0.40629 11.5108
399 4CVN ADP 0.0001402 0.52573 11.5183
400 3CH5 GDP 0.000000000991 0.75405 11.5385
401 2XTN GTP 0.00001269 0.51329 11.5385
402 1UPT GTP 0.00000000006929 0.74161 11.6667
403 1C9K 5GP 0.02058 0.40464 11.6667
404 1ZD9 GDP 0.0000001438 0.61569 11.7021
405 2BO4 FLC 0.03941 0.40179 11.7021
406 1YZQ GNP 0.0000000000373 0.70945 11.7647
407 1Z08 GNP 0.00000004439 0.61537 11.7647
408 1UAD GNP 0.0000000002588 0.69107 12
409 2NGR GDP 0.00000001614 0.6956 12.0419
410 2NGR AF3 0.00001057 0.58408 12.0419
411 4ITR GDP 0.0000008334 0.58201 12.0419
412 1W0J ADP 0.0001476 0.42199 12.234
413 3DDC GNP 0.0000000001856 0.68241 12.2699
414 3SBD GNP 0.0000000007104 0.67352 12.2995
415 1TE2 PGA 0.007716 0.43617 12.3894
416 4DID GDP 0.0000001335 0.65135 12.4352
417 2HV8 GTP 0.000000001553 0.65993 12.5
418 1U8Z GDP 0.0000000205 0.62931 12.5
419 3BFX A3P 0.005882 0.41206 12.5
420 2HT6 GDP 0.00000000008989 0.83227 12.6437
421 1HTW ADP 0.00007453 0.51887 12.6582
422 4Y4V DAL 0.00328 0.45609 12.6844
423 2Q37 3AL 0.03558 0.40082 12.7072
424 3KTA AP5 0.001555 0.44595 12.7168
425 4M9Q GNP 0.000000000009075 0.77903 12.7753
426 1GRN GDP 0.00000009516 0.63165 12.8079
427 1GRN AF3 0.000007782 0.59101 12.8079
428 3R7F CP 0.02455 0.41155 12.8289
429 1R0X ATP 0.000352 0.49833 12.9754
430 2W83 GTP 0.0000000000763 0.73028 12.987
431 2V7Q ATP 0.0000901 0.50876 13.0137
432 2V7Q ADP 0.0003468 0.49247 13.0137
433 2CK3 ANP 0.001701 0.43589 13.0137
434 2CK3 ADP 0.002289 0.4195 13.0137
435 5UFQ GNP 0.000000009031 0.62934 13.1148
436 1TX4 ALF GDP 0.000000001743 0.67381 13.1313
437 3Q72 GNP 0.000000001083 0.77752 13.253
438 2J59 GTP 0.00000000006052 0.73446 13.253
439 1O3Y GTP 0.0000000001584 0.71709 13.253
440 2GK6 ADP 0.009771 0.4298 13.2979
441 4NTX AMR 0.02847 0.40361 13.3333
442 3REF GDP 0.00000006078 0.61687 13.4021
443 4E03 ADP 0.0001347 0.50646 13.5922
444 3A4M ADP 0.00005515 0.5468 13.8462
445 1OXV ANP 0.0001039 0.52518 13.881
446 2KIN ADP 0.000001579 0.64448 14
447 4YC7 GNP 0.000000003249 0.67079 14.0957
448 4PU6 ASP 0.01176 0.42559 14.2132
449 4QRH 0O2 0.007997 0.40292 14.2857
450 1WDT GTP 0.0000000007443 0.71661 14.3177
451 5X40 ACP 0.001564 0.41016 14.3836
452 5E95 GDP 0.00000004849 0.64486 14.433
453 5H9I XAN 0.02588 0.40697 14.5833
454 1DAR GDP 0.0000000009544 0.76717 14.7651
455 1GUA GNP 0.0000000002589 0.67677 14.8148
456 3KUD GDP 0.00000001391 0.65206 14.8148
457 5DI3 GNP 0.0000000001089 0.73328 14.8289
458 5IRC GDP 0.0000001792 0.63607 14.9254
459 1FQJ ALF 0.0000005343 0.65899 14.966
460 1FQK ALF 0.000001426 0.6425 14.966
461 1FQJ GDP 0.00000003104 0.62182 14.966
462 1FQK GDP 0.00000006546 0.60836 14.966
463 4QM7 GTP 0.0001817 0.50634 15.2047
464 3BC1 GNP 0.0000000001592 0.69951 15.2542
465 2W2X GSP 0.0000000002108 0.73074 15.3226
466 2FH5 GTP 0.00000000006156 0.75386 15.4206
467 1ZCB GDP 0.0000001975 0.57572 15.4696
468 3AB3 GDP 0.00000005553 0.56574 15.4696
469 1OFH ADP 0.0003238 0.48258 15.4839
470 5EE5 GTP 0.00000000004186 0.75089 15.493
471 1KSH GDP 0.00000000001352 0.69599 15.5914
472 3CX8 GSP 0.0000000003399 0.64774 15.9763
473 4NON GDP 0.0000003537 0.54589 16.1538
474 3DKP ADP 0.002261 0.45223 16.3265
475 3ZIA ATP 0.0001494 0.5043 16.3934
476 3ZIA ADP 0.0002546 0.48217 16.3934
477 1E96 GTP 0.000000001264 0.6635 16.6667
478 1EK0 GNP 0.00000000005919 0.7167 17.0588
479 4BAS GNP 0.000000000338 0.71244 17.0854
480 4D0G GTP 0.000000001055 0.69149 17.3913
481 2X77 GDP 0.000000006552 0.71449 17.4603
482 4GOJ GNP 0.000000000003325 0.79751 17.5
483 1LFD GNP 0.00000000005389 0.71833 18.3908
484 5IRN ADP 0.0002607 0.4817 18.883
485 2WZ5 MET 0.01579 0.40972 18.9542
486 2D7C GTP 0.000000001846 0.65692 19.0476
487 4YLG GDP 0.00000001253 0.67135 19.0751
488 1MKY GDP 0.0000000001326 0.80952 19.1344
489 3TD3 GLY 0.007581 0.43556 19.5122
490 2WJG GDP 0.000000003124 0.74173 19.6809
491 4LC1 GDP 0.000000004035 0.73624 19.8813
492 5UWO GNP 0.0000000001526 0.68577 20
493 1X1R GDP 0.00000007075 0.58246 20.2247
494 1Z0K GTP 0.0000000000536 0.73665 20.2899
495 1DS6 GDP 0.00000002893 0.69398 20.3125
496 1ZC3 GNP 0.0000000008387 0.65726 20.354
497 3A1S GDP 0.0000004501 0.62589 20.5426
498 2F9L GDP 0.00000009735 0.60119 20.603
499 2WJH GDP 0.0000000029 0.56314 21.0843
500 2WJH FLC 0.0000008914 0.49019 21.0843
501 1BG2 ADP 0.000000954 0.65585 21.2308
502 3ZQ6 ADP ALF 0.0001072 0.4594 21.2963
503 1R4A GNP 0.0000000003896 0.69223 21.5686
504 5J1S ATP 0.002462 0.41494 21.9512
505 1J2J GTP 0.0000000001532 0.7177 22.2222
506 1NF3 GNP 0.000000003368 0.64648 22.6562
507 1F6B GDP 0.000000006224 0.71556 22.7273
508 3T12 GDP ALF 0.0000000003583 0.71137 22.7273
509 3T1O GDP 0.00000003016 0.67254 22.7273
510 5UWS GNP 0.0000000002527 0.66415 22.7273
511 5O2T GSP 0.0000000002951 0.67495 22.9947
512 3DOE GTP 0.00000000002721 0.74889 23.6364
513 3CYI ATP 0.02658 0.40951 23.6364
514 1YVD GNP 0.00000000009376 0.70871 23.6686
515 3WYG GTP 0.0000000003274 0.66041 23.6842
516 4RD0 GDP 0.0000000000002444 0.84556 23.8554
517 1G7S GDP 0.00000000007979 0.80682 23.9374
518 5UWU GNP 0.0000000001461 0.68647 25
519 2ZTS ADP 0.002245 0.43056 25.8964
520 4NCN GTP 0.000000000000217 0.83609 26.3982
521 4TMZ GSP 0.0000000000002919 0.83074 26.3982
522 4HDQ GNP 0.000000001006 0.65407 26.9231
523 1CXZ GSP 0.0000000002244 0.71998 27.907
524 5FG3 GDP 0.000000000001761 0.91879 29.9776
525 4ZKD GDP 0.00000000000192 0.75925 30.4251
526 4V0K GDP 0.0000004756 0.56639 32.5444
527 2VOH CIT 0.01069 0.42381 34.6154
528 4B47 GDP 0.000000000009819 0.88098 34.7107
529 1Y3A GDP 0.0000002047 0.58778 37.5
530 1KK1 GNP 0.00000000007651 0.83582 38.5366
531 4J0Q GDP 0.00000000007652 0.83582 47.1132
Pocket No.: 2; Query (leader) PDB : 3WXM; Ligand: GTP; Similar sites found: 15
This union binding pocket(no: 2) in the query (biounit: 3wxm.bio4) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2OAT PFM 0.01139 0.40107 2.05011
2 4NZ6 DGL 0.006719 0.4393 2.8754
3 3EF0 ALF 0.03304 0.40367 4.03226
4 3PNA CMP 0.02822 0.40015 4.54545
5 1CR1 TTP 0.001054 0.41272 5.06757
6 4FBL SPD 0.02404 0.4037 6.04982
7 1QXA GLY GLY GLY 0.04079 0.40415 6.38298
8 4AFK FLC 0.04096 0.40068 7.97872
9 2V2G BEZ 0.03695 0.40218 8.15451
10 1INN MET 0.02202 0.41364 9.03614
11 1DNP MHF 0.01846 0.41323 9.04255
12 2CE7 ADP 0.0005518 0.40033 9.30851
13 4O48 ASP 0.01859 0.41561 11.1446
14 1W0J ADP BEF 0.001527 0.4012 12.234
15 3BY9 SIN 0.03129 0.4073 15
Pocket No.: 3; Query (leader) PDB : 3WXM; Ligand: GTP; Similar sites found: 8
This union binding pocket(no: 3) in the query (biounit: 3wxm.bio1) has 25 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1MLY ACZ PLP 0.00704 0.40061 2.7972
2 4ADC PLP 0.01702 0.40345 2.95567
3 3ZL8 ADP 0.008457 0.40031 3.43249
4 2ZPA ADP 0.001735 0.40013 3.45745
5 1IZC PYR 0.04135 0.4038 4.12979
6 4UOX PLP 0.01839 0.40181 4.28266
7 1AQU A3P 0.01201 0.40002 7.07071
8 1GJW GLC 0.03298 0.40115 7.15884
Pocket No.: 4; Query (leader) PDB : 3WXM; Ligand: GTP; Similar sites found: 7
This union binding pocket(no: 4) in the query (biounit: 3wxm.bio3) has 26 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2X1L ADN 0.01447 0.40467 2.48092
2 2RNF UM3 0.0347 0.4009 5.05319
3 1NST A3P 0.01131 0.40273 5.84615
4 3IUY AMP 0.0206 0.40462 6.14035
5 2XOM GAL GAL GAL 0.04553 0.40021 10.5263
6 2IL4 COA 0.01412 0.40167 10.6796
7 5CSS G3P 0.02418 0.40114 12.8319
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