Receptor
PDB id Resolution Class Description Source Keywords
3WYF 2.22 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF XPO1P-YRB2P-GSP1P-GTP COMPLEX SACCHAROMYCES CEREVISIAE AWRI796 HEAT REPEAT NUCLEAR EXPORT GTP-BINDING PROTEIN-GTP-BINDINGINHIBITOR COMPLEX
Ref.: STRUCTURAL INSIGHTS INTO HOW YRB2P ACCELERATES THE OF THE XPO1P NUCLEAR EXPORT COMPLEX CELL REP V. 9 983 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GTP A:301;
D:301;
Valid;
Valid;
none;
none;
submit data
523.18 C10 H16 N5 O14 P3 c1nc2...
MG A:302;
D:302;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3WYF 2.22 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF XPO1P-YRB2P-GSP1P-GTP COMPLEX SACCHAROMYCES CEREVISIAE AWRI796 HEAT REPEAT NUCLEAR EXPORT GTP-BINDING PROTEIN-GTP-BINDINGINHIBITOR COMPLEX
Ref.: STRUCTURAL INSIGHTS INTO HOW YRB2P ACCELERATES THE OF THE XPO1P NUCLEAR EXPORT COMPLEX CELL REP V. 9 983 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 3WYF - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 3WYF - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 3WYF - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GTP; Similar ligands found: 147
No: Ligand ECFP6 Tc MDL keys Tc
1 GTP 1 1
2 GP3 0.921053 0.973684
3 GDP 0.909091 1
4 GSP 0.853659 0.948718
5 GNH 0.82716 0.986667
6 G1R 0.819277 0.986667
7 GAV 0.811765 0.961039
8 GNP 0.809524 0.973684
9 GCP 0.797619 0.973684
10 5GP 0.797468 0.986486
11 G 0.797468 0.986486
12 GMV 0.764706 0.973684
13 G2R 0.764045 0.961039
14 G5P 0.755319 0.973684
15 GTG 0.752688 0.936709
16 G2P 0.747126 0.961039
17 G3A 0.744681 0.973684
18 GDD 0.741935 0.961039
19 GKE 0.741935 0.961039
20 GDC 0.741935 0.961039
21 0O2 0.736264 0.986486
22 GP2 0.729412 0.961039
23 6CK 0.726316 0.936709
24 Y9Z 0.723404 0.902439
25 GPG 0.717391 0.961039
26 GFB 0.715789 0.961039
27 GDR 0.715789 0.961039
28 GDP MG 0.712644 0.923077
29 GDP BEF 0.704545 0.9
30 GPD 0.704082 0.925
31 JB2 0.693878 0.961039
32 GKD 0.693878 0.961039
33 GCP G 0.692308 0.935065
34 GDX 0.686869 0.973684
35 ALF 5GP 0.685393 0.888889
36 GTP MG 0.681319 0.923077
37 BEF GDP 0.681319 0.888889
38 GH3 0.681319 0.973333
39 YGP 0.677083 0.901235
40 G3D 0.67033 0.986486
41 GDP AF3 0.659574 0.888889
42 GDP ALF 0.659574 0.888889
43 DGT 0.659341 0.923077
44 GMP 0.658228 0.88
45 G4P 0.655914 0.986486
46 JB3 0.653846 0.948718
47 NGD 0.647619 0.961039
48 CAG 0.642202 0.880952
49 2MD 0.62963 0.891566
50 G G 0.622449 0.935065
51 MGP 0.619565 0.961039
52 U2G 0.616822 0.936709
53 6G0 0.612903 0.961039
54 MGD 0.612613 0.891566
55 TPG 0.608696 0.840909
56 CG2 0.605505 0.936709
57 GDP 7MG 0.601942 0.911392
58 FEG 0.601852 0.879518
59 ZGP 0.59633 0.869048
60 MD1 0.591304 0.891566
61 PGD 0.591304 0.925
62 3GP 0.590909 0.946667
63 GPX 0.581633 0.946667
64 DGI 0.580645 0.923077
65 IDP 0.576087 0.972973
66 DBG 0.567797 0.948718
67 FE9 0.555556 0.776596
68 2GP 0.555556 0.96
69 G4M 0.547619 0.880952
70 BGO 0.544643 0.924051
71 I2C FE2 CMO CMO 0.538462 0.808989
72 ATP 0.537634 0.92
73 G1G 0.533898 0.925
74 AQP 0.531915 0.92
75 5FA 0.531915 0.92
76 G A A A 0.525862 0.923077
77 U A G G 0.521368 0.935065
78 01G 0.518868 0.902439
79 ITT 0.510638 0.868421
80 P2G 0.510638 0.883117
81 GGM 0.504274 0.901235
82 G1R G1R 0.504065 0.924051
83 DGP 0.5 0.910256
84 PGD O 0.5 0.850575
85 MGO 0.5 0.864198
86 P1G 0.5 0.871795
87 DG 0.5 0.910256
88 GTA 0.495495 0.936709
89 B4P 0.489362 0.894737
90 AP5 0.489362 0.894737
91 IMP 0.489362 0.959459
92 7DT 0.484536 0.906667
93 G G U 0.482143 0.935065
94 GPC 0.479339 0.879518
95 G C 0.478992 0.9
96 BA3 0.478723 0.894737
97 ADP 0.473684 0.92
98 G2Q 0.471698 0.961039
99 G7M 0.46875 0.948052
100 25L 0.458716 0.907895
101 A2D 0.457447 0.894737
102 RGT 0.45045 0.909091
103 AGS 0.45 0.873418
104 SAP 0.45 0.873418
105 SGP 0.44898 0.82716
106 U G A 0.448529 0.888889
107 A4P 0.445378 0.869048
108 G G G RPC 0.442623 0.875
109 ACQ 0.441176 0.896104
110 ANP 0.441176 0.896104
111 8GT 0.441176 0.875
112 APC G U 0.44 0.886076
113 G U34 0.438017 0.888889
114 6AD 0.436893 0.841463
115 G G G C 0.433071 0.9125
116 UP5 0.432203 0.873418
117 35G 0.431373 0.933333
118 C2E 0.431373 0.921053
119 PCG 0.431373 0.933333
120 A G C C 0.429688 0.911392
121 5GP 5GP 0.427184 0.883117
122 TAT 0.427184 0.884615
123 APR 0.425743 0.894737
124 AR6 0.425743 0.894737
125 AN2 0.424242 0.907895
126 7DD 0.424242 0.906667
127 DG DG 0.423423 0.865854
128 AD9 0.421569 0.896104
129 M33 0.42 0.883117
130 7D4 0.42 0.835443
131 UCG 0.419847 0.911392
132 H6Y 0.419048 0.946667
133 G C C C 0.416667 0.924051
134 ACP 0.415842 0.896104
135 T5A 0.414634 0.802326
136 MGQ 0.412844 0.935897
137 ADQ 0.412844 0.871795
138 A1R 0.412844 0.839506
139 MGT 0.411215 0.823529
140 A G U 0.410072 0.888889
141 93A 0.41 0.833333
142 A22 0.407407 0.907895
143 CA0 0.405941 0.896104
144 ATF 0.40566 0.884615
145 AGO 0.404762 0.888889
146 MGV 0.401786 0.890244
147 CGP 0.4 0.86747
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3WYF; Ligand: GTP; Similar sites found: 413
This union binding pocket(no: 1) in the query (biounit: 3wyf.bio1) has 28 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2F5X ASP 0.01661 0.42055 2.88462
2 1J1R ADE 0.03495 0.40344 3.36134
3 1W5T ANP 0.001856 0.43363 3.65297
4 1W5T ADP 0.003931 0.42657 3.65297
5 4O48 ASP 0.02089 0.41693 3.65297
6 1D8T GDP 0.000000001768 0.75973 3.78151
7 2BVN GNP 0.0000000003835 0.75652 3.78151
8 5I0H ADP BEF 0.0000004257 0.51263 3.78151
9 2OFW ADX 0.0008725 0.44052 3.84615
10 2HCJ GDP 0.0000000007473 0.52644 3.8806
11 2RCN GDP 0.00000000005751 0.83387 4.10959
12 4YS0 ADP 0.002325 0.43697 4.12621
13 2NCD ADP 0.000004153 0.61687 4.20168
14 4GBM A3P 0.006006 0.40505 4.20168
15 2WOJ ADP ALF 0.00005198 0.47854 4.23729
16 2PEZ DAT 0.0007816 0.43464 4.46927
17 2PEZ GGZ 0.0007816 0.43464 4.46927
18 1KK1 GNP 0.000000004784 0.75045 4.56621
19 2OG2 MLI 0.00001507 0.58496 4.56621
20 1F9V ADP 0.000002821 0.40618 4.61095
21 2ZFI ADP 0.000006651 0.58157 4.62185
22 3ZQ6 ADP ALF 0.00006512 0.47466 4.62185
23 4IOK XPO 0.001842 0.4233 4.62185
24 1QHG ATP 0.005772 0.42266 4.62185
25 1X6V ADP 0.0008911 0.42082 4.62185
26 4IOK ADP 0.002976 0.40589 4.62185
27 1H5R THM 0.01872 0.40948 4.77816
28 1G6H ADP 0.0000006132 0.6848 5.02283
29 2XAU ADP 0.0001262 0.50558 5.02283
30 3FVQ ATP 0.0005198 0.45778 5.02283
31 2ATJ BHO 0.01212 0.42816 5.02283
32 1NST A3P 0.00818 0.41204 5.02283
33 4RW3 DKA 0.009375 0.40601 5.02283
34 1GOJ ADP 0.0000002988 0.69363 5.04202
35 4MKG AP5 0.003102 0.41914 5.06912
36 4AG5 ADP 0.00001484 0.58768 5.10204
37 1QF5 RPL 0.003513 0.45461 5.10441
38 3VX3 ADP 0.000107 0.49268 5.24194
39 3TK1 GDP 0.00000000487 0.76315 5.46218
40 4ZG4 VO4 ADP 0.000001968 0.50378 5.46218
41 3MD0 GDP 0.000000001861 0.77139 5.47945
42 4MDB RLT 0.0281 0.41279 5.47945
43 4TTQ ATP 0.00009168 0.5248 5.5814
44 5KUT GDP 0.0000001159 0.49147 5.82011
45 1XMV ADP 0.0001384 0.50959 5.88235
46 4Q1A UDP 0.01165 0.44108 5.88235
47 4Q1A 2XZ 0.01165 0.44108 5.88235
48 1DAR GDP 0.00000001865 0.70875 5.93607
49 3DC4 ADP 0.000000307 0.66882 5.93607
50 1WF3 GNP 0.000000002165 0.63693 5.93607
51 4WZ6 ATP 0.00002881 0.57239 5.93607
52 2DPY ADP 0.0003904 0.50611 5.93607
53 1G41 ADP 0.0002201 0.49409 5.93607
54 2JLR ANP 0.0002818 0.48371 5.93607
55 3QKT ANP 0.000347 0.45318 5.93607
56 1QAN SAH 0.0006835 0.44473 5.93607
57 5X40 ACP 0.0005827 0.41424 5.93607
58 3DZD ADP 0.001026 0.4576 5.97826
59 4KBF AMP 0.003719 0.44952 6.0274
60 3B5J 12D 0.0000124 0.58463 6.17284
61 1IHU AF3 0.00009971 0.48437 6.28183
62 1IHU ADP 0.0001278 0.47531 6.28183
63 2AWN ADP 0.0000002805 0.71478 6.30252
64 2GK6 ADP 0.002655 0.46245 6.30252
65 2C9O ADP 0.0001419 0.4824 6.35965
66 4P4T GDP 0.000003597 0.55835 6.38889
67 2XTZ GSP 0.00000000004588 0.72759 6.39269
68 4A4Z ANP 0.008392 0.42696 6.39269
69 3BP1 GUN 0.01227 0.42508 6.39269
70 3MBI HSX 0.02868 0.40393 6.39269
71 1FNN ADP 0.0002057 0.48002 6.42674
72 4LJ9 ACP 0.000808 0.47769 6.48968
73 3UIE ANP 0.00008093 0.51476 6.5
74 5N69 ADP 0.00003123 0.52814 6.53266
75 2QEN ADP 0.0003399 0.475 6.57143
76 1OYY AGS 0.003294 0.44725 6.69216
77 5KSZ GCP 0.00000496 0.57242 6.72269
78 1IN4 ADP 0.0004815 0.46356 6.72269
79 2FAH GDP 0.0009768 0.4586 6.72269
80 2PL3 ADP 0.0003351 0.50295 6.77966
81 1V8K ANP 0.0000002731 0.65066 6.82927
82 1YRB GDP 0.0000000001175 0.78041 6.84932
83 1OXV ANP 0.00005097 0.54473 6.84932
84 1XKV ATP 0.00006946 0.51791 6.84932
85 3EC1 GDP 0.00000002261 0.51288 6.84932
86 3ZFD ANP 0.00000004332 0.5116 6.84932
87 3VM7 GLC 0.01339 0.4229 6.84932
88 1OS1 ATP 0.001492 0.41279 6.84932
89 1OS1 PYR 0.0015 0.40817 6.84932
90 1SGJ OAA 0.02487 0.40802 6.84932
91 2BEK ATP 0.0002692 0.4659 7.00389
92 1JWY GDP 0.00000233 0.58056 7.14286
93 1JWY ADP 0.00002106 0.54939 7.14286
94 3TBK ANP 0.002044 0.46841 7.14286
95 1YTM ATP 0.0003158 0.46723 7.14286
96 5NUL FMN 0.01132 0.40559 7.24638
97 3B9Q MLI 0.00001978 0.59401 7.28477
98 4NON GDP 0.0000002923 0.56224 7.30594
99 1P9B GDP 0.0001197 0.49562 7.30594
100 4P32 ADP 0.0007212 0.44757 7.30594
101 1P9B HDA 0.006484 0.44523 7.30594
102 1CR1 TTP 0.000621 0.40523 7.30594
103 1VHT BA3 0.001249 0.45824 7.33945
104 4BQS K2Q 0.0004777 0.44734 7.38636
105 4BQS ADP 0.0004777 0.40316 7.38636
106 5L3R GCP 0.000005434 0.52756 7.50853
107 5MZN ADP 0.001986 0.46907 7.56302
108 1M7G AV2 0.000004053 0.60089 7.58294
109 1M7G ADP 0.0006253 0.42623 7.58294
110 1M7G ADX 0.0005743 0.41645 7.58294
111 4RD0 GDP 0.00000000001911 0.67421 7.76256
112 2XT3 ADP 0.0000006459 0.66819 7.76256
113 3AB3 GDP 0.00000002175 0.56297 7.76256
114 2Z5F A3P 0.003904 0.4195 7.76256
115 2ODE ALF GDP 0.0000000003907 0.67721 7.80142
116 4OI4 ATP 0.00246 0.42136 7.82609
117 4MKF AP5 0.00452 0.41349 7.8341
118 3NHB ADP 0.000006852 0.60695 7.84314
119 2GDJ ANP 0.0002571 0.50248 7.95455
120 5FG3 GDP 0.0000000004701 0.53312 7.98319
121 4IDN GNP 0.00008215 0.48797 7.98319
122 2Q2Y ADP 0.0002397 0.46466 7.98319
123 2Q2Y MKR 0.0002549 0.46231 7.98319
124 4LC1 GDP 0.0000000398 0.69234 8.01187
125 1TAD ALF 0.000000001181 0.64468 8.02469
126 1TAD GDP 0.000000001181 0.64468 8.02469
127 2VF7 ADP 0.0002425 0.49775 8.21918
128 1L2T ATP 0.0006955 0.44074 8.21918
129 4PJ3 ANP 0.005352 0.4242 8.21918
130 1M0S CIT 0.02692 0.40536 8.21918
131 3B7G ANP 0.0008247 0.47188 8.26087
132 1RZM PEP 0.02782 0.40868 8.28402
133 2VVG ADP 0.0000004547 0.40121 8.28571
134 1FP6 ADP 0.00006717 0.51267 8.3045
135 4MZQ 1VU 0.005094 0.41786 8.33333
136 2QZ4 ADP 0.000226 0.49354 8.39695
137 2C77 GNP 0.0000000001264 0.74662 8.40336
138 2C78 GNP 0.0000000001506 0.73357 8.40336
139 2ZR9 DTP 0.00008335 0.52686 8.40336
140 2B8W ALF 5GP 0.000007109 0.52275 8.40336
141 1F5N GNP 0.00001519 0.49976 8.40336
142 1P4V GLY 0.01892 0.41804 8.40336
143 3R7F CP 0.02071 0.41797 8.40336
144 5KSP GDP 0.000002558 0.59393 8.42105
145 5BQ5 ADP BEF 0.0001661 0.49991 8.46561
146 1PUJ GNP 0.000000006542 0.69923 8.6758
147 1AZT GSP 0.0000000001699 0.67621 8.6758
148 3BFX A3P 0.007135 0.41132 8.6758
149 4FRZ ADP 0.00000215 0.40823 8.6758
150 3BOS CDP 0.0001575 0.51308 8.67769
151 1WY7 SAH 0.006425 0.40382 8.69565
152 2D2F ADP 0.00004523 0.57181 8.8
153 1YQT ADP 0.00001019 0.59711 8.82353
154 4IEE AGS 0.0003873 0.49974 8.82353
155 3DCJ THH 0.007915 0.41627 8.83721
156 1U0J ADP 0.0001638 0.51883 9.13242
157 2HF9 GSP 0.00000002434 0.66365 9.29204
158 1U4J MAN 0.0414 0.40073 9.32203
159 2XTN GTP 0.000004008 0.53845 9.40171
160 1NRJ GTP 0.00000000004341 0.76689 9.49367
161 4LPS GDP 0.0000001232 0.65803 9.58904
162 1G3Q ADP 0.00001135 0.56245 9.58904
163 1ION ADP 0.00003078 0.53472 9.58904
164 3FYH ADP 0.003125 0.41384 9.62733
165 1JJV ATP 0.0001163 0.53773 9.70874
166 1APZ ASP 0.007185 0.43974 9.92908
167 4QM7 GTP 0.00005534 0.53572 9.94152
168 3BFV ADP 0.00003269 0.54711 9.9631
169 3VPD BUA 0.006327 0.43856 9.96441
170 3VPD CIT 0.02312 0.42448 9.96441
171 4YMU ATP 0.00001915 0.56645 10
172 1JI0 ATP 0.00002545 0.56827 10.0457
173 5E5U MLI 0.00344 0.4227 10.0503
174 2CHG ANP 0.0002971 0.47765 10.177
175 4QOS ADP 0.0006413 0.47201 10.1887
176 1SVI GDP 0.000000005489 0.7474 10.2564
177 2WDQ TEO 0.01679 0.42031 10.4348
178 3WXM GTP 0.0000000004947 0.65352 10.5023
179 2IS6 ADP 0.0002029 0.5076 10.5023
180 5L3W GDP 0.00001272 0.43744 10.5023
181 5I34 GDP 0.00002034 0.42177 10.5023
182 4GOX A3P 0.002629 0.42015 10.5023
183 2IYL GDP 0.000003156 0.5977 10.5042
184 5LB3 ADP 0.0004726 0.49532 10.5618
185 3MWL 8OX 0.03379 0.40419 10.628
186 3PQC GDP 0.0000002357 0.63534 10.7692
187 2C04 GCP 0.00003301 0.52109 10.7744
188 4HSE ADP 0.0001294 0.51103 10.8312
189 1G8S MET 0.00887 0.438 10.8696
190 1BO4 COA 0.009763 0.42367 11.3095
191 1SKQ GDP 0.000000009072 0.73625 11.3445
192 4HI0 GDP 0.0000004625 0.59101 11.4155
193 4R43 GDP 0.0009241 0.47479 11.4155
194 1NY5 ADP 0.002364 0.43664 11.4155
195 3COB ADP 0.0000007485 0.40982 11.4155
196 2HK9 ATR 0.02345 0.40455 11.4155
197 1G7C 5GP 0.000000585 0.63418 11.7021
198 4KFU ACP 0.000002383 0.63053 11.7925
199 3DKP ADP 0.0004727 0.4893 11.8721
200 2J5V PCA 0.04482 0.40709 11.8721
201 4R2I ANP 0.0005156 0.49978 11.9048
202 1W7J ADP BEF 0.000007981 0.54915 11.9205
203 1NJF AGS 0.0003471 0.41947 12.1849
204 1NJF ADP 0.0001535 0.41885 12.1849
205 3IUY AMP 0.007764 0.42865 12.2807
206 5CK5 GDP 0.00000000009205 0.54445 12.3288
207 4CVN ADP 0.00003851 0.55884 12.4088
208 2IXE ATP 0.0004588 0.45599 12.5461
209 3W5J GDP 0.0000002483 0.68364 12.7451
210 4NCN GTP 0.00000000002527 0.7568 12.7854
211 1G7S GDP 0.000000007247 0.7179 12.7854
212 1SQ5 ADP 0.0002279 0.49906 12.7854
213 1FQK ALF 0.0000002338 0.68648 12.9252
214 1FQK GDP 0.00000003939 0.62274 12.9252
215 3RLF ANP 0.0005058 0.45023 13.0252
216 2CK3 ANP 0.001337 0.44378 13.0252
217 2CK3 ADP 0.001781 0.42726 13.0252
218 1W0J ADP 0.0002074 0.40413 13.0252
219 2DT9 THR 0.02509 0.40694 13.1737
220 1GXU 2HP 0.0004947 0.50148 13.1868
221 1CS4 GSP 0.0000000001821 0.68727 13.2075
222 1T5C ADP 0.000001695 0.64967 13.242
223 2V7Q ATP 0.0001094 0.50853 13.6364
224 2V7Q ADP 0.0003228 0.49756 13.6364
225 1JJ7 ADP 0.0000006854 0.68005 13.6986
226 1H65 GDP 0.00001059 0.52606 13.6986
227 3KJI ADP 0.00003072 0.43456 13.6986
228 1YXM ADE 0.01969 0.40086 13.6986
229 3KTA AP5 0.0007211 0.46473 13.7363
230 3CX8 GSP 0.0000000002947 0.66705 13.7931
231 4H1V GNP 0.000009258 0.54622 13.8211
232 3BER AMP 0.007308 0.42996 13.8655
233 3H4S ADP 0.000001238 0.40357 14.0741
234 1SVK ALF GDP 0.0000000008904 0.66589 14.1553
235 1BH2 GSP 0.0000000004062 0.66083 14.1553
236 1TQ4 GDP 0.0000000349 0.64002 14.1553
237 5L3V GDP 0.000002866 0.58375 14.3813
238 5L3S GNP 0.00002815 0.4696 14.4295
239 1Y3A GDP 0.0000000782 0.61023 14.6119
240 1Z6T ADP 0.000699 0.46074 14.6119
241 3A4M ADP 0.00001558 0.57944 14.6154
242 1F2U ATP 0.0006126 0.436 15.0685
243 4WZA ADP 0.00007407 0.50507 15.126
244 4WZA ACP 0.00009578 0.50026 15.126
245 1R6B ADP 0.0002272 0.49912 15.126
246 4DCT GDP 0.000000003141 0.73557 15.5251
247 1K6M AGS 0.001393 0.43174 15.5251
248 4IHQ ADP 0.0002471 0.50971 15.5462
249 1XP8 AGS 0.0001934 0.51514 15.9664
250 2VB6 ADP BEF 0.00004086 0.4555 16.1074
251 3IIJ ADP 0.00001968 0.55809 16.1111
252 1LVG ADP 0.000002976 0.41479 16.1616
253 3RC3 ANP 0.003077 0.45373 16.3866
254 1D2E GDP 0.000000101 0.64396 16.4384
255 2WJG GDP 0.00000001034 0.72151 16.4894
256 5HCN GCP 0.000000003648 0.73241 16.895
257 2BIF SIN 0.002058 0.42964 16.895
258 2BIF ANP 0.001353 0.42652 16.895
259 3KIF GDL 0.03929 0.40069 16.9811
260 3H86 AP5 0.002526 0.41695 17.1875
261 5M04 GDP 0.0000000003427 0.53491 17.2269
262 2W58 ADP 0.00000303 0.63846 17.3267
263 4K91 SIN 0.01764 0.41259 17.341
264 4XTR ATP 0.0000847 0.44682 17.5115
265 4XVU ATP 0.00009125 0.44572 17.5115
266 4XTR ADP 0.00008023 0.43079 17.5115
267 1G6O ADP 0.0001693 0.49951 17.6471
268 3E70 GDP 0.000002075 0.59836 17.9878
269 3QF7 ANP 0.001688 0.41995 18
270 3FWY ADP 0.00001606 0.53533 18.1529
271 4WOP CTP 0.0002377 0.42048 18.2222
272 1MKY GDP 0.000000001182 0.76844 18.2648
273 3DEF GDP 0.000003723 0.5711 18.2648
274 2QN6 GDP 0.0000000008364 0.78913 18.2796
275 5KDO GDP 0.00000019 0.60788 19.1176
276 1GOT GDP 0.0000002223 0.5979 19.1176
277 2WJH GDP 0.00000000901 0.52628 19.2771
278 2WJH FLC 0.0000007976 0.47533 19.2771
279 1B0U ATP 0.0005371 0.47068 20.0913
280 4PU6 ASP 0.009586 0.43315 20.6107
281 2PMP C5P 0.04504 0.40108 20.625
282 3A1S GDP 0.0000009437 0.61501 20.9302
283 4M9Q GNP 0.00000000002283 0.76864 21.0046
284 3ZIA ATP 0.0002092 0.50087 21.0145
285 3ZIA ADP 0.0002963 0.4827 21.0145
286 5H56 ADP 0.001982 0.41576 21.0256
287 5H56 TYD 0.001982 0.41576 21.0256
288 1D2N ANP 0.007308 0.40758 21.3235
289 1FQJ ALF 0.0000001486 0.69252 21.4286
290 1FQJ GDP 0.00000002348 0.63217 21.4286
291 1MR3 G3D 0.000000001159 0.54427 21.547
292 1UPT GTP 0.000000000003004 0.80635 22.2222
293 4PFO ADP 0.0001574 0.4461 22.3744
294 1B7T ADP 0.00004571 0.52656 22.4359
295 2FH5 GTP 0.00000000001111 0.79274 22.7027
296 2A5F GTP 0.00000000004091 0.73862 22.8571
297 1OFH ADP 0.0005004 0.47713 22.9885
298 1S9D GDP 0.000000003591 0.73274 23.1707
299 1RE0 GDP 0.0000000003708 0.53146 23.1707
300 1F6B GDP 0.000000003052 0.73617 23.2323
301 3T12 GDP ALF 0.0000000004945 0.71146 23.2323
302 3T1O GDP 0.00000003709 0.51858 23.2323
303 2WIC GNP 0.00000001875 0.69782 23.2877
304 4R98 GNH 0.0000004822 0.47192 23.2877
305 1GP2 GDP 0.0000003396 0.58346 23.9437
306 2X7I CIT 0.01243 0.41841 24.026
307 1J2J GTP 0.000000000002152 0.80171 24.0964
308 1O3Y GTP 0.000000000003303 0.7939 24.0964
309 1ZUI SKM 0.00004242 0.43595 24.4048
310 1KK8 BEF ADP 0.00001169 0.5416 25.1799
311 1M2O GNP 0.0000000006943 0.64822 25.2632
312 3ZS9 ADP ALF 0.00004591 0.48069 26.3158
313 1FZQ GDP 0.0000000006281 0.78213 26.5193
314 2GJ8 ALF GDP 0.000000004319 0.64057 27.907
315 1YZG GDP 0.000000003983 0.73055 28.4916
316 2QTV GNP 0.0000000001145 0.66734 28.7425
317 2WKQ GTP 0.0000000000008391 0.81888 28.7671
318 1LES GLC FRU 0.02095 0.40556 28.8462
319 1KSH GDP 0.00000000003939 0.6528 29.0323
320 4BAS GNP 0.0000000005146 0.6255 29.6482
321 2J0V GDP 0.000000002564 0.54109 29.717
322 3REF GDP 0.000000001067 0.69717 30.4124
323 1ZJ6 G3D 0.000000003179 0.73531 30.4813
324 2OM2 GDP 0.0000002591 0.602 30.5556
325 4B47 GDP 0.00000000006889 0.84452 31.0502
326 4DID GDP 0.000000002782 0.73813 31.0881
327 4V0K GDP 0.0000003965 0.57439 31.3609
328 1GWN GTP 0.00000000004052 0.65657 31.7073
329 2GCO GNP 0.00000000004657 0.78737 31.8408
330 2GCN GDP 0.000000003914 0.59548 31.8408
331 1DS6 GDP 0.0000000007955 0.77701 32.2917
332 1RYH GNP 0.00000000001286 0.83805 32.5123
333 1I4D GDP 0.00000000107 0.78368 32.8125
334 1OW3 GDP 0.00000000169 0.58255 33.1606
335 1E96 GTP 0.00000000000002653 0.85855 33.3333
336 3SBD GNP 0.0000000000004678 0.80813 33.6898
337 1QHH ATP 0.01344 0.41277 33.913
338 2W2X GSP 0.00000000002433 0.77787 34.0541
339 4D0N GDP 0.000000003268 0.52522 34.0541
340 1CXZ GSP 0.000000000005452 0.79527 34.0659
341 1A4R GNH 0.0000000005678 0.73794 34.555
342 1A4R GDP 0.0000000007056 0.72359 34.555
343 5HPY GDP 0.000000001184 0.58477 34.5946
344 1G4U AF3 0.0000002421 0.68902 34.7826
345 1G4U GDP 0.00000008954 0.62984 34.7826
346 1MH1 GNP 0.00000000001842 0.71712 34.9462
347 2NGR AF3 0.0000000005646 0.81219 35.0785
348 2NGR GDP 0.0000000001547 0.79919 35.0785
349 1GRN AF3 0.000000001032 0.79847 35.0785
350 1GRN GDP 0.0000000003687 0.74647 35.0785
351 4ITR GDP 0.00000003421 0.64847 35.0785
352 1KMQ GNP 0.000000000001691 0.80611 35.3261
353 1M7B GTP 0.00000000005223 0.76338 35.3261
354 1NF3 GNP 0.000000000001489 0.7878 35.3846
355 2FJU GSP 0.000000000002026 0.82502 35.3933
356 1HE1 AF3 0.00000009749 0.69494 35.7955
357 1HE1 GDP 0.00000001723 0.65341 35.7955
358 1TX4 ALF GDP 0.00000000002365 0.758 36.1582
359 2D7D ADP 0.001598 0.46292 37.5
360 5IRC GDP 0.00000000458 0.54712 37.6344
361 3T5G GDP 0.0000000009278 0.56267 38.1215
362 1XTQ GDP 0.0000000003648 0.64303 38.9831
363 1ZD9 GDP 0.00000000007025 0.76825 39.3617
364 1R4A GNP 0.00000000007371 0.72809 39.3939
365 2ZEJ GDP 0.0000008301 0.54989 40.7609
366 4DSU GDP 0.0000000000161 0.73701 41.7989
367 5UQW GDP 0.00000000004014 0.68532 41.7989
368 3BC1 GNP 0.0000000000002986 0.81601 42.0513
369 2F9L GDP 0.0000000006892 0.69651 42.2111
370 2BCG GDP 0.0000000005614 0.72802 42.233
371 2G77 GDP 0.0000000004473 0.74265 42.4242
372 2G77 AF3 0.0000001724 0.6908 42.4242
373 1OIV GDP 0.0000000007053 0.648 42.9319
374 5TAR GDP 0.0000000001658 0.77346 43.2432
375 5TB5 GDP 0.0000000001011 0.5867 43.2432
376 1OIX GDP 0.0000000000003345 0.77281 43.4555
377 2CJW GDP 0.00000000004179 0.84078 43.75
378 1VG8 GNP 0.00000000000006961 0.8098 43.9614
379 1VG0 GDP 0.00000000007379 0.60814 43.9614
380 4U5X GNP 0.000000000174 0.75069 44.9438
381 3RWO GDP 0.0000000001388 0.70815 45.9459
382 1Z06 GNP 0.000000000001432 0.7986 46.0317
383 2A9K GDP 0.0000000001384 0.61363 46.5241
384 5O2T GSP 0.00000000000003209 0.84425 46.7456
385 3Q85 GNP 0.0000000001214 0.8177 46.7456
386 3Q72 GNP 0.00000000007627 0.84226 46.988
387 1YZN GNP 0.00000000000003253 0.84403 47.027
388 5XCO GDP 0.00000000002973 0.6196 47.3684
389 4C4P GNP 0.000000000001716 0.75657 47.3988
390 5UFQ GNP 0.00000000008645 0.68242 47.5904
391 2C5L GTP 0.00000000000001621 0.85604 47.9769
392 1NVU GTP 0.00000000000002354 0.84958 48.1928
393 2UZI GTP 0.00000000000003686 0.80788 48.1928
394 1CLU DBG 0.0000000001422 0.72365 48.1928
395 1Z0J GTP 0.0000000000002801 0.80688 48.2353
396 2HV8 GTP 0.000000000005725 0.72732 48.2558
397 2HT6 GDP 0.00000000002859 0.86403 48.2759
398 1LFD GNP 0.0000000000000534 0.84625 48.503
399 4K81 GTP 0.0000000000002572 0.79844 48.538
400 2A5J GDP 0.00000000004437 0.81248 48.6911
401 1NVV GNP 0.000000000000007216 0.86999 48.7952
402 3KUD GDP 0.0000000000004663 0.85288 48.7952
403 1WQ1 GDP 0.000000000008181 0.77736 48.7952
404 1WQ1 AF3 0.00000001283 0.75954 48.7952
405 1KY3 GDP 0.0000000001809 0.7717 48.9011
406 2D7C GTP 0.000000000003211 0.7743 49.1018
407 1YVD GNP 0.0000000000008378 0.7979 49.1124
408 1VG1 GDP 0.00000000001541 0.60087 49.1892
409 1VG9 GDP 0.00000000003668 0.59007 49.1892
410 3DDC GNP 0.000000000000008438 0.86726 49.3976
411 1G16 GDP 0.000000001226 0.69457 49.4118
412 2FFQ GSP 0.0000000000004615 0.77875 49.7076
413 1Z0F GDP 0.00000000005467 0.82117 49.7207
414 3QBT GNP 0.00000000000008937 0.83719 50
Pocket No.: 2; Query (leader) PDB : 3WYF; Ligand: GTP; Similar sites found: 24
This union binding pocket(no: 2) in the query (biounit: 3wyf.bio2) has 28 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3F81 STT 0.0392 0.40205 3.82514
2 2V2G BEZ 0.01385 0.4317 4.29185
3 3QDK QDK 0.04917 0.40129 5.47945
4 1SZ2 BGC 0.02628 0.41 5.93607
5 2JK0 ASP 0.02904 0.40897 6.15385
6 4IP7 FBP 0.009194 0.41323 6.30252
7 3MB5 SAM 0.005687 0.4031 6.39269
8 1T9D P22 0.01138 0.42922 6.84932
9 2YIP YIO 0.03668 0.40258 7.24638
10 2P3V SRT 0.03188 0.40478 7.30594
11 1R18 SAH 0.007551 0.40087 7.48899
12 1I9G SAM 0.008709 0.40118 7.56302
13 5DG2 GAL GLC 0.02559 0.40346 8.14815
14 1YBH P22 0.01877 0.40943 9.15254
15 4TQK NAG 0.03008 0.40793 9.2437
16 1IK4 PGH 0.01199 0.4152 9.86842
17 4U60 SIA 0.01839 0.41408 10.5023
18 3TW1 AHN 0.03096 0.4069 10.9705
19 1M26 GAL A2G 0.0362 0.4036 11.2782
20 2ZJ5 ADP 0.04312 0.40035 12.3288
21 2WZF BGC 0.009075 0.43647 13.8655
22 1QD0 RR6 0.02745 0.4011 14.0625
23 3LN9 FLC 0.01062 0.41397 15.8273
24 2GMP NAG MAN 0.0408 0.40052 28.3105
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