Receptor
PDB id Resolution Class Description Source Keywords
3ZWE 1.75 Å NON-ENZYME: BINDING STRUCTURE OF BAMBL, A LECTIN FROM BURKHOLDERIA AMBIFARIA, COMPLEXED WITH BLOOD GROUP B EPITOPE BURKHOLDERIA AMBIFARIA SUGAR BINDING PROTEIN CYSTIC FIBROSIS B-PROPELLER HUMAN HISTO-BLOOD GROUP
Ref.: FUCOSE-BINDING LECTIN FROM OPPORTUNISTIC PATHOGEN BURKHOLDERIA AMBIFARIA BINDS TO BOTH PLANT AND HUMA OLIGOSACCHARIDIC EPITOPES. J.BIOL.CHEM. V. 287 4335 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
BGC GLA GAL FUC B:101;
C:101;
Valid;
Valid;
none;
none;
submit data
650.58 n/a O(C1O...
FUC A:110;
B:110;
C:110;
Valid;
Valid;
Valid;
none;
none;
none;
submit data
164.156 C6 H12 O5 C[C@H...
GAL FUC A:102;
Valid;
none;
submit data
326.298 n/a O(C1O...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3ZW2 1.6 Å NON-ENZYME: BINDING STRUCTURE OF THE LECTIN BAMBL FROM BURKHOLDERIA AMBIFARIA IN WITH BLOOD GROUP H TYPE 1 TETRASACCHARIDE BURKHOLDERIA AMBIFARIA SUGAR BINDING PROTEIN CYSTIC FIBROSIS B-PROPELLER HUMAN HISTO-BLOOD GROUP
Ref.: FUCOSE-BINDING LECTIN FROM OPPORTUNISTIC PATHOGEN BURKHOLDERIA AMBIFARIA BINDS TO BOTH PLANT AND HUMA OLIGOSACCHARIDIC EPITOPES. J.BIOL.CHEM. V. 287 4335 2012
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 473 families.
1 3ZWE - FUC C6 H12 O5 C[C@H]1[C@....
2 3ZZV - NAG GAL FUC n/a n/a
3 3ZW2 Kd = 26.1 uM GLA NAG GAL FUC n/a n/a
70% Homology Family (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 355 families.
1 3ZWE - FUC C6 H12 O5 C[C@H]1[C@....
2 3ZZV - NAG GAL FUC n/a n/a
3 3ZW2 Kd = 26.1 uM GLA NAG GAL FUC n/a n/a
4 5AJB Kd = 25.7 uM FUC NAG GLA GAL n/a n/a
5 2BT9 Kd = 0.64 uM MFU C7 H14 O5 C[C@H]1[C@....
6 2BS6 - XYS GAL FUC n/a n/a
7 4I6S - FUL C6 H12 O5 C[C@H]1[C@....
8 5AJC - FUC NAG n/a n/a
9 3ZI8 - FU4 C6 H12 O4 C[C@H]1[C@....
10 2BS5 Kd = 250 nM BGC GAL FUC n/a n/a
50% Homology Family (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 272 families.
1 3ZWE - FUC C6 H12 O5 C[C@H]1[C@....
2 3ZZV - NAG GAL FUC n/a n/a
3 3ZW2 Kd = 26.1 uM GLA NAG GAL FUC n/a n/a
4 5AJB Kd = 25.7 uM FUC NAG GLA GAL n/a n/a
5 2BT9 Kd = 0.64 uM MFU C7 H14 O5 C[C@H]1[C@....
6 2BS6 - XYS GAL FUC n/a n/a
7 4I6S - FUL C6 H12 O5 C[C@H]1[C@....
8 5AJC - FUC NAG n/a n/a
9 3ZI8 - FU4 C6 H12 O4 C[C@H]1[C@....
10 2BS5 Kd = 250 nM BGC GAL FUC n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: BGC GLA GAL FUC; Similar ligands found: 226
No: Ligand ECFP6 Tc MDL keys Tc
1 BGC GLA GAL FUC 1 1
2 A2G GAL BGC FUC 0.7375 0.73913
3 FUC GAL GLC 0.735294 1
4 GLC GAL FUC 0.735294 1
5 FUC LAT 0.735294 1
6 BGC GAL FUC 0.735294 1
7 LAT FUC 0.735294 1
8 GLA GAL NAG FUC GAL GLC 0.729412 0.73913
9 GLC GAL NAG GAL FUC A2G 0.634409 0.693878
10 A2G GAL NAG FUC GAL GLC 0.634409 0.693878
11 FUC BGC GAL 0.633803 1
12 GLA GAL FUC 0.619718 1
13 GLA GLA FUC 0.619718 1
14 FUC GAL GLA 0.619718 1
15 FUC GLA GLA 0.619718 1
16 GAL GAL FUC 0.619718 1
17 BGC BMA 0.609375 0.970588
18 MAL MAL 0.609375 0.942857
19 CBK 0.609375 0.970588
20 GLC BGC 0.609375 0.970588
21 BMA GAL 0.609375 0.970588
22 BGC GAL 0.609375 0.970588
23 GAL BGC 0.609375 0.970588
24 B2G 0.609375 0.970588
25 GLC GAL 0.609375 0.970588
26 GAL GLC 0.609375 0.970588
27 BGC GLC 0.609375 0.970588
28 CBI 0.609375 0.970588
29 MAL 0.609375 0.970588
30 MAB 0.609375 0.970588
31 GLA GLA 0.609375 0.970588
32 LBT 0.609375 0.970588
33 N9S 0.609375 0.970588
34 LAT 0.609375 0.970588
35 GLA GAL 0.609375 0.970588
36 BMA BMA 0.609375 0.970588
37 GLC FUC GAL FUC A2G 0.586207 0.723404
38 BGC FUC GAL FUC A2G 0.586207 0.723404
39 BGB 0.580247 0.790698
40 A2G GAL NAG FUC 0.579545 0.693878
41 FUC GAL NAG GAL BGC 0.577778 0.73913
42 GLA GAL BGC 0.577465 0.970588
43 GLA GAL GAL 0.577465 0.970588
44 GLC BGC BGC BGC BGC BGC 0.573529 0.970588
45 GLC BGC BGC 0.573529 0.970588
46 BGC BGC BGC BGC BGC BGC 0.573529 0.970588
47 BMA BMA BMA BMA BMA 0.573529 0.970588
48 CEX 0.573529 0.970588
49 BGC BGC BGC GLC 0.573529 0.970588
50 MLR 0.573529 0.970588
51 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.573529 0.970588
52 GLC GAL GAL 0.573529 0.970588
53 BGC GLC GLC GLC GLC GLC GLC 0.573529 0.970588
54 MAN MAN BMA BMA BMA BMA 0.573529 0.970588
55 BGC GLC GLC GLC GLC 0.573529 0.970588
56 BGC GLC GLC 0.573529 0.970588
57 MTT 0.573529 0.970588
58 BMA MAN BMA 0.573529 0.970588
59 GLA GAL GLC 0.573529 0.970588
60 CEY 0.573529 0.970588
61 GLC GLC GLC GLC GLC GLC GLC 0.573529 0.970588
62 CE6 0.573529 0.970588
63 B4G 0.573529 0.970588
64 GLC GLC GLC GLC GLC GLC GLC GLC 0.573529 0.970588
65 MAN BMA BMA BMA BMA 0.573529 0.970588
66 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.573529 0.970588
67 CTR 0.573529 0.970588
68 CT3 0.573529 0.970588
69 GLC BGC GLC 0.573529 0.970588
70 CE5 0.573529 0.970588
71 GLC BGC BGC BGC BGC 0.573529 0.970588
72 MT7 0.573529 0.970588
73 DXI 0.573529 0.970588
74 CTT 0.573529 0.970588
75 CE8 0.573529 0.970588
76 MAN BMA BMA 0.573529 0.970588
77 BGC GLC GLC GLC 0.573529 0.970588
78 GLC GLC BGC GLC GLC GLC GLC 0.573529 0.970588
79 BMA BMA BMA 0.573529 0.970588
80 GAL GAL GAL 0.573529 0.970588
81 GLC GLC GLC GLC GLC 0.573529 0.970588
82 GLC GLC BGC 0.573529 0.970588
83 BMA BMA BMA BMA BMA BMA 0.573529 0.970588
84 BGC GAL NAG GAL FUC FUC 0.553191 0.723404
85 GLC GAL NAG GAL FUC FUC 0.553191 0.723404
86 BGC BGC BGC BGC 0.546667 0.970588
87 BGC BGC BGC BGC BGC BGC BGC BGC 0.546667 0.970588
88 MAN BMA BMA BMA BMA BMA 0.541667 0.942857
89 BMA BMA BMA BMA BMA BMA MAN 0.541667 0.942857
90 GLA MAN RAM ABE 0.54023 0.918919
91 FUC GAL NDG 0.52439 0.73913
92 FUC GAL NAG 0.52439 0.73913
93 FUL GAL NAG 0.52439 0.73913
94 DR2 0.52439 0.73913
95 NDG GAL FUC 0.52439 0.73913
96 GAL NAG GAL BGC 0.517647 0.755556
97 BGC GAL NAG GAL 0.517647 0.755556
98 LAT NAG GAL 0.517647 0.755556
99 FUC GAL NAG A2G FUC 0.516129 0.693878
100 NAG GAL FUC FUC A2G 0.516129 0.693878
101 FUC BGC GAL NAG GAL 0.505263 0.73913
102 GLA MAN RAM TYV GLA MAN GLC RAM TYV 0.50505 0.894737
103 ABD 0.5 0.772727
104 GLC G6D ACI GLC 0.494505 0.809524
105 GLC G6D ADH GLC 0.494505 0.809524
106 GLC ACI G6D BGC 0.494505 0.809524
107 GLC ACI GLD GLC 0.494505 0.809524
108 GAL NGA GLA BGC GAL 0.494382 0.755556
109 FUC NAG GAL 0.493976 0.73913
110 GAL NAG FUC 0.493976 0.73913
111 GAL NDG FUC 0.493976 0.73913
112 FUC NDG GAL 0.493976 0.73913
113 GLA MAN RAM ABE GLA MAN RAM ABE 0.489796 0.894737
114 GLA MAN RAM TYV GLA MAN RAM TYV 0.489796 0.894737
115 GLC GAL NAG GAL 0.488636 0.755556
116 GAL FUC 0.486111 0.970588
117 FUC GAL 0.486111 0.970588
118 GLC AGL GLC HMC 0.479167 0.73913
119 GAL NAG GAL FUC 0.477778 0.73913
120 GLA NAG GAL FUC 0.477778 0.73913
121 GLA MAN RAM RAM ABE MAN GLA 0.475728 0.894737
122 BMA BMA GLA BMA BMA 0.47561 0.970588
123 GLC ACI G6D GLC 0.473684 0.755556
124 GLC GLC G6D ACI GLC GLC GLC 0.473684 0.809524
125 GLC ACI GLD GAL 0.473684 0.755556
126 FUC BGC GAL NAG 0.473118 0.73913
127 NAG GAL FUC 0.465116 0.73913
128 DR3 0.465116 0.73913
129 GLC GLC GLC BGC 0.463415 0.970588
130 BGC BGC GLC 0.460526 0.970588
131 NAG GAL BGC 0.45977 0.755556
132 MAG FUC GAL 0.458824 0.708333
133 FUC GAL NAG A2G 0.458333 0.62963
134 NAG FUC 0.455696 0.695652
135 GAL NDG FUC FUC 0.454545 0.723404
136 FUC NAG GAL FUC 0.454545 0.723404
137 FUC GAL NAG FUC 0.454545 0.723404
138 GLC GLC DAF BGC 0.454545 0.755556
139 FUC GAL NDG FUC 0.454545 0.723404
140 BMA MAN MAN 0.454545 0.970588
141 ARE 0.454545 0.755556
142 G6D GLC ACI GLD GLC ACI GLD GLC BGC 0.454545 0.702128
143 GAL NAG FUC FUC 0.454545 0.723404
144 FUC NDG GAL FUC 0.454545 0.723404
145 ACR GLC GLC GLC 0.454545 0.755556
146 GLC GLC AGL HMC GLC 0.454545 0.755556
147 AAO 0.454545 0.755556
148 GLC GLC ACI G6D GLC GLC 0.454545 0.755556
149 FUC GAL NGA 0.454545 0.755556
150 BCW 0.454545 0.723404
151 BDZ 0.454545 0.723404
152 XYS GAL FUC 0.452381 0.971429
153 GLA MMA ABE 0.452381 0.894737
154 NGA GLA GAL BGC 0.450549 0.755556
155 ACG 0.45 0.717391
156 5GO 0.448718 0.647059
157 FUC GLA A2G 0.448276 0.73913
158 A2G GLA FUC 0.448276 0.73913
159 FUC GL0 A2G 0.448276 0.73913
160 A2G GAL FUC 0.448276 0.73913
161 NGA GAL FUC 0.448276 0.73913
162 FUC GAL A2G 0.448276 0.73913
163 NGA GAL BGC 0.447059 0.755556
164 U63 0.445946 0.868421
165 FUC GAL NAG GAL FUC 0.442105 0.723404
166 SGA BGC 0.441558 0.6875
167 GLA EGA 0.44 0.971429
168 BGC BGC BGC XYS GAL 0.43956 0.916667
169 GLC GLC GLC GLC GLC GLC 0.439024 0.970588
170 DR5 0.438356 0.971429
171 MMA MAN 0.438356 0.971429
172 LAT GLA 0.43662 0.970588
173 MAN MAN BMA 0.434211 0.970588
174 GLC GLC BGC XYS BGC XYS 0.433333 0.916667
175 MAN GLC 0.430556 0.970588
176 M3M 0.430556 0.970588
177 LB2 0.430556 0.970588
178 NDG GAL 0.43038 0.755556
179 GAL NDG 0.43038 0.755556
180 NLC 0.43038 0.755556
181 GAL GAL GLC EMB MEC 0.43 0.641509
182 BGA 0.428571 0.618182
183 MAN MAN MAN GLC 0.426829 0.970588
184 BMA BMA MAN 0.426667 0.942857
185 EAG RAM RAM GLC RAM NAG RAM RAM GLC RAM 0.425743 0.68
186 XYS BGC BGC BGC BGC XYS BGC BGC BGC 0.423913 0.916667
187 BGC BGC BGC XYS BGC BGC 0.423913 0.916667
188 XYS BGC BGC XYS BGC XYS BGC BGC BGC 0.423913 0.916667
189 DAF GLC 0.422222 0.809524
190 DAF BGC 0.422222 0.809524
191 FUC GAL MAG FUC 0.422222 0.708333
192 GLC GLC GLC G6D ADH GLC 0.421569 0.708333
193 BGC BGC BGC GLC BGC BGC 0.421053 0.970588
194 BGC BGC BGC BGC BGC 0.421053 0.970588
195 GLC BGC BGC BGC 0.421053 0.970588
196 BGC BGC BGC ASO BGC BGC ASO 0.421053 0.970588
197 BGC BGC BGC 0.421053 0.970588
198 GLC BGC BGC BGC BGC BGC BGC 0.421053 0.970588
199 GLC GLC FRU 0.420455 0.846154
200 GAL BGC BGC XYS 0.420455 0.916667
201 FUC NAG 0.419753 0.717391
202 NAG GAL GAL 0.418605 0.755556
203 GLA MAN ABE 0.418605 0.944444
204 MAN BMA NAG 0.418605 0.755556
205 BHE 0.418605 0.790698
206 GLA GAL NAG 0.418605 0.755556
207 2M4 0.416667 0.970588
208 MAN MAN 0.416667 0.970588
209 BGC BGC 0.416667 0.970588
210 ACI GLD GLC GAL 0.414894 0.809524
211 DAF BGC GLC 0.414894 0.809524
212 DAF GLC GLC 0.414894 0.809524
213 BMA MAN 0.413333 0.888889
214 FUC NAG GLA GAL 0.412371 0.723404
215 BHG FUC 0.411765 0.790698
216 FUC BHG 0.411765 0.790698
217 4YA 0.411765 0.790698
218 BGC BGC BGC XYS BGC XYS GAL 0.408163 0.916667
219 GAL BGC BGC BGC XYS BGC XYS 0.408163 0.916667
220 MVP 0.405063 0.717391
221 GLC GLC XYP 0.404762 0.970588
222 MDM 0.4 0.971429
223 M13 0.4 0.971429
224 TXT 0.4 0.790698
225 GAC 0.4 0.790698
226 GAL MBG 0.4 0.971429
Ligand no: 2; Ligand: FUC; Similar ligands found: 9
No: Ligand ECFP6 Tc MDL keys Tc
1 G6D 1 1
2 XXR 1 1
3 FUL 1 1
4 FUC 1 1
5 RAM 1 1
6 FCA 1 1
7 RM4 1 1
8 FCB 1 1
9 FUF 0.424242 0.846154
Ligand no: 3; Ligand: GAL FUC; Similar ligands found: 249
No: Ligand ECFP6 Tc MDL keys Tc
1 GAL FUC 1 1
2 CBI 0.615385 0.941176
3 LAT 0.615385 0.941176
4 GLC GAL 0.615385 0.941176
5 CBK 0.615385 0.941176
6 BGC GAL 0.615385 0.941176
7 GAL BGC 0.615385 0.941176
8 LBT 0.615385 0.941176
9 BMA GAL 0.615385 0.941176
10 MAL MAL 0.615385 0.914286
11 BMA BMA 0.615385 0.941176
12 GLA GAL 0.615385 0.941176
13 MAB 0.615385 0.941176
14 B2G 0.615385 0.941176
15 N9S 0.615385 0.941176
16 GAL GLC 0.615385 0.941176
17 GLA GLA 0.615385 0.941176
18 GLC BGC 0.615385 0.941176
19 BGC GLC 0.615385 0.941176
20 BGC BMA 0.615385 0.941176
21 MAL 0.615385 0.941176
22 GLA MAN RAM ABE 0.597222 0.891892
23 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.571429 0.941176
24 CTR 0.571429 0.941176
25 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.571429 0.941176
26 CE5 0.571429 0.941176
27 BGC BGC BGC GLC 0.571429 0.941176
28 BMA BMA MAN 0.571429 0.914286
29 GLC GLC GLC GLC GLC 0.571429 0.941176
30 CEX 0.571429 0.941176
31 CTT 0.571429 0.941176
32 GLC BGC BGC BGC BGC BGC 0.571429 0.941176
33 BGC GLC GLC GLC 0.571429 0.941176
34 CE8 0.571429 0.941176
35 DXI 0.571429 0.941176
36 CE6 0.571429 0.941176
37 BGC BGC BGC BGC BGC BGC 0.571429 0.941176
38 GLA GAL GLC 0.571429 0.941176
39 GLC BGC GLC 0.571429 0.941176
40 GAL GAL GAL 0.571429 0.941176
41 GLC GLC GLC GLC GLC GLC GLC GLC 0.571429 0.941176
42 CT3 0.571429 0.941176
43 BMA MAN BMA 0.571429 0.941176
44 MAN MAN BMA BMA BMA BMA 0.571429 0.941176
45 GLC GLC BGC 0.571429 0.941176
46 BMA BMA BMA 0.571429 0.941176
47 BGC GLC GLC 0.571429 0.941176
48 BGC GLC GLC GLC GLC 0.571429 0.941176
49 BMA BMA BMA BMA BMA 0.571429 0.941176
50 GLC BGC BGC BGC BGC 0.571429 0.941176
51 MTT 0.571429 0.941176
52 GLC GAL GAL 0.571429 0.941176
53 BMA BMA BMA BMA BMA BMA 0.571429 0.941176
54 MAN BMA BMA 0.571429 0.941176
55 MLR 0.571429 0.941176
56 GLC BGC BGC 0.571429 0.941176
57 GLC GLC GLC GLC GLC GLC GLC 0.571429 0.941176
58 MAN BMA BMA BMA BMA 0.571429 0.941176
59 CEY 0.571429 0.941176
60 B4G 0.571429 0.941176
61 BGC GLC GLC GLC GLC GLC GLC 0.571429 0.941176
62 GLC GLC BGC GLC GLC GLC GLC 0.571429 0.941176
63 MT7 0.571429 0.941176
64 MAN BMA BMA BMA BMA BMA 0.559322 0.914286
65 BMA BMA BMA BMA BMA BMA MAN 0.559322 0.914286
66 M3M 0.555556 0.941176
67 LB2 0.555556 0.941176
68 MAN GLC 0.555556 0.941176
69 BGC BGC 0.537037 0.941176
70 2M4 0.537037 0.941176
71 GLA MBG 0.537037 0.942857
72 MAN MAN 0.537037 0.941176
73 TRE 0.531915 0.941176
74 GLA GAL GAL 0.52459 0.941176
75 GLA GAL BGC 0.52459 0.941176
76 GLA MAN RAM TYV GLA MAN RAM TYV 0.511905 0.868421
77 GLA MAN RAM ABE GLA MAN RAM ABE 0.511905 0.868421
78 LAT GLA 0.509091 0.941176
79 DR5 0.508772 0.942857
80 MMA MAN 0.508772 0.942857
81 BGC BGC BGC 0.508475 0.941176
82 BGC BGC BGC ASO BGC BGC ASO 0.508475 0.941176
83 BGC BGC BGC GLC BGC BGC 0.508475 0.941176
84 GLC BGC BGC BGC BGC BGC BGC 0.508475 0.941176
85 BGC BGC BGC BGC BGC 0.508475 0.941176
86 GLC BGC BGC BGC 0.508475 0.941176
87 GLA EGA 0.508475 0.942857
88 BGC BGC GLC 0.508197 0.941176
89 BMA MAN MAN 0.5 0.941176
90 GLA MAN RAM TYV GLA MAN GLC RAM TYV 0.494253 0.868421
91 BGC BGC BGC BGC 0.492308 0.941176
92 BGC BGC BGC BGC BGC BGC BGC BGC 0.492308 0.941176
93 FUC BGC GAL 0.492308 0.970588
94 BGC GLA GAL FUC 0.486111 0.970588
95 CGC 0.483871 0.941176
96 NOY BGC 0.483333 0.711111
97 MDM 0.482759 0.942857
98 M13 0.482759 0.942857
99 GAL MBG 0.482759 0.942857
100 GLA MAN RAM RAM ABE MAN GLA 0.477778 0.868421
101 LAT FUC 0.477612 0.970588
102 FUC LAT 0.477612 0.970588
103 GLC GAL FUC 0.477612 0.970588
104 FUC GAL GLC 0.477612 0.970588
105 BGC GAL FUC 0.477612 0.970588
106 GLA GLA FUC 0.476923 0.970588
107 FUC GAL GLA 0.476923 0.970588
108 GAL GAL FUC 0.476923 0.970588
109 GLA GAL FUC 0.476923 0.970588
110 FUC GLA GLA 0.476923 0.970588
111 MAN MAN BMA 0.47541 0.941176
112 BMA MAN 0.474576 0.861111
113 GAL BGC BGC XYS 0.472222 0.888889
114 GAL NDG 0.46875 0.733333
115 NDG GAL 0.46875 0.733333
116 GAL NGA 0.46875 0.733333
117 8VZ 0.46875 0.673469
118 GAL A2G 0.46875 0.733333
119 GAL MGC 0.46875 0.702128
120 A2G GAL 0.46875 0.733333
121 NLC 0.46875 0.733333
122 ABD 0.467532 0.75
123 U63 0.466667 0.842105
124 GLC ACI G6D BGC 0.4625 0.785714
125 GLC G6D ACI GLC 0.4625 0.785714
126 GLC ACI GLD GLC 0.4625 0.785714
127 GLC G6D ADH GLC 0.4625 0.785714
128 MVP 0.460317 0.695652
129 T6P 0.457627 0.727273
130 RZM 0.457627 0.652174
131 BMA BMA GLA BMA BMA 0.457143 0.941176
132 GLC GLC XYP 0.455882 0.941176
133 GLC GLC GLC GLC GLC GLC 0.455882 0.941176
134 GLC GAL NAG GAL 0.454545 0.733333
135 9MR 0.451613 0.704545
136 MAN MNM 0.451613 0.711111
137 IFM BMA 0.451613 0.704545
138 MAL EDO 0.451613 0.888889
139 IFM BGC 0.451613 0.704545
140 BMA IFM 0.451613 0.704545
141 DOM 0.45 0.888889
142 BGC GAL NAG GAL 0.447368 0.733333
143 GAL NAG GAL BGC 0.447368 0.733333
144 LAT NAG GAL 0.447368 0.733333
145 GLA GAL BGC 5VQ 0.446154 0.891892
146 GLC GLC GLC BGC 0.442857 0.941176
147 GLC GLC G6D ACI GLC GLC GLC 0.440476 0.785714
148 QV4 0.440476 0.733333
149 FUC NAG GAL 0.438356 0.717391
150 GAL NAG MAN 0.438356 0.733333
151 GAL NAG FUC 0.438356 0.717391
152 FUC NDG GAL 0.438356 0.717391
153 MAN NAG GAL 0.438356 0.733333
154 GAL NDG FUC 0.438356 0.717391
155 ABL 0.4375 0.666667
156 BGC BGC BGC XYS GAL 0.435897 0.888889
157 BMA FRU 0.435484 0.794872
158 FRU GAL 0.435484 0.794872
159 5QP 0.435484 0.833333
160 P3M 0.434783 0.727273
161 GAL GAL SO4 0.432836 0.666667
162 AMG 0.431373 0.857143
163 GYP 0.431373 0.857143
164 MMA 0.431373 0.857143
165 MBG 0.431373 0.857143
166 GLA MAN ABE 0.430556 0.916667
167 MAN MAN MAN MAN 0.428571 0.941176
168 MAN MAN BMA MAN 0.428571 0.941176
169 GLC GLC BGC XYS BGC XYS 0.428571 0.888889
170 ABC 0.428571 0.695652
171 BGC OXZ 0.428571 0.632653
172 GLA GAL GLC NBU 0.426471 0.846154
173 GLA NAG GAL FUC 0.425 0.717391
174 GAL NGA GLA BGC GAL 0.425 0.733333
175 GAL NAG GAL FUC 0.425 0.717391
176 NGA GAL BGC 0.424658 0.733333
177 GLC ACI G6D GLC 0.423529 0.733333
178 GLC ACI GLD GAL 0.423529 0.733333
179 NAG GAL GAL NAG GAL 0.423077 0.6875
180 GAL NGA A2G 0.422535 0.673469
181 FMO 0.421875 0.820513
182 NOJ GLC 0.421875 0.688889
183 GLC DMJ 0.421875 0.688889
184 MAN MAN MAN GLC 0.42029 0.941176
185 FUC GAL 0.419355 1
186 MAG FUC GAL 0.418919 0.6875
187 XYS BGC BGC XYS BGC XYS BGC BGC BGC 0.417722 0.888889
188 BGC BGC BGC XYS BGC BGC 0.417722 0.888889
189 XYS BGC BGC BGC BGC XYS BGC BGC BGC 0.417722 0.888889
190 BMA GLA 0.416667 0.941176
191 MLB 0.416667 0.941176
192 BGC 0.416667 0.848485
193 WOO 0.416667 0.848485
194 BMA 0.416667 0.848485
195 MAN BMA 0.416667 0.941176
196 GLC 0.416667 0.848485
197 BGC GLA 0.416667 0.941176
198 GLA GLC 0.416667 0.941176
199 GAL 0.416667 0.848485
200 GIV 0.416667 0.848485
201 GXL 0.416667 0.848485
202 ALL 0.416667 0.848485
203 LAK 0.416667 0.941176
204 GAL GAL 0.416667 0.941176
205 GLA 0.416667 0.848485
206 GLA BGC 0.416667 0.941176
207 GLA BMA 0.416667 0.941176
208 LSE 0.416667 0.6875
209 MAN 0.416667 0.848485
210 G3I 0.414286 0.727273
211 LMT 0.414286 0.785714
212 G2I 0.414286 0.727273
213 DMU 0.414286 0.785714
214 UMQ 0.414286 0.785714
215 LMU 0.414286 0.785714
216 MAN DGO 0.412698 0.861111
217 MAN BMA NAG 0.410959 0.733333
218 GLA MMA ABE 0.410959 0.868421
219 NAG GAL GAL 0.410959 0.733333
220 GLA GAL NAG 0.410959 0.733333
221 MAN MAN MAN BMA MAN 0.407895 0.941176
222 ISX 0.40625 0.72093
223 MAN MMA MAN 0.405797 0.942857
224 NAG BMA 0.405797 0.653061
225 GLC GLC GLC GLC 0.405797 0.941176
226 G2F BGC BGC BGC BGC BGC 0.405797 0.820513
227 ACR GLC GLC GLC 0.404494 0.733333
228 AAO 0.404494 0.733333
229 ARE 0.404494 0.733333
230 GLC GLC ACI G6D GLC GLC 0.404494 0.733333
231 GLC GLC DAF BGC 0.404494 0.733333
232 GLC GLC AGL HMC GLC 0.404494 0.733333
233 MAN 7D1 0.403226 0.837838
234 GLC GLC GLC GLC BGC 0.403226 0.941176
235 MAN MAN MAN 0.403226 0.941176
236 GLC GLC GLC 0.403226 0.941176
237 GLC GLC GLC GLC GLC BGC 0.403226 0.941176
238 4RS 0.402985 0.825
239 M5S 0.402778 0.941176
240 MAN BMA MAN MAN MAN 0.402778 0.941176
241 NAG GAL BGC 0.402597 0.733333
242 GAL BGC BGC BGC XYS BGC XYS 0.4 0.888889
243 XGP 0.4 0.697674
244 BGC BGC BGC XYS BGC XYS GAL 0.4 0.888889
245 M1P 0.4 0.697674
246 G1P 0.4 0.697674
247 MAN IFM 0.4 0.72093
248 GL1 0.4 0.697674
249 GLC IFM 0.4 0.72093
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3ZW2; Ligand: GLA NAG GAL FUC; Similar sites found: 59
This union binding pocket(no: 1) in the query (biounit: 3zw2.bio1) has 20 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4NS0 PIO 0.0005088 0.50129 None
2 2BOS GLA GAL 0.001595 0.47771 None
3 2BOS GLA GAL GLC 0.002007 0.46601 None
4 1DZT ATY 0.002996 0.45071 None
5 4M1U A2G MBG 0.007431 0.43291 None
6 5I8T LAC 0.005757 0.43114 None
7 5HV0 AKG 0.005036 0.41563 None
8 1DZT TPE 0.01707 0.41018 None
9 3MTX PGT 0.01468 0.41003 None
10 3LQV ADE 0.02629 0.40528 None
11 4CQK PIO 0.01952 0.40507 None
12 4MJ0 SIA SIA GAL 0.02019 0.40348 None
13 2HKA C3S 0.003482 0.40273 None
14 5F6U 5VK 0.03088 0.40036 None
15 2HZQ STR 0.0006581 0.48248 2.29885
16 4XBA 5GP 0.009071 0.40393 2.29885
17 5KWY C3S 0.004754 0.41278 3.44828
18 3OID TCL 0.01603 0.40857 3.44828
19 5WSY 7UC 0.01451 0.40634 3.44828
20 3VV1 GAL FUC 0.0116 0.40616 3.44828
21 4J25 OGA 0.004826 0.43633 4.5977
22 4G05 JZ3 0.02251 0.42188 4.5977
23 4FFG 0U8 0.01407 0.41954 4.5977
24 4AZT LY2 0.006679 0.41839 4.5977
25 4FFG LBS 0.006991 0.41491 4.5977
26 5DCH 1YO 0.01674 0.409 4.5977
27 3N1S 5GP 0.002351 0.43531 5.04202
28 3E7S AT2 0.007754 0.42758 5.74713
29 2FCU AKG 0.007115 0.42709 5.74713
30 1EOC 4NC 0.004671 0.42585 5.74713
31 5DBX ANP 0.004109 0.42396 5.74713
32 3X01 AMP 0.01039 0.4201 5.74713
33 1Y7P RIP 0.01233 0.41817 5.74713
34 1AV5 AP2 0.001149 0.44985 6.89655
35 4X17 SIA SIA 0.01228 0.40992 6.89655
36 3QRC SCR 0.0009298 0.44494 8.04598
37 1S68 AMP 0.006432 0.4287 8.04598
38 5W0N UPU 0.008993 0.42133 8.04598
39 3KFF XBT 0.01218 0.41464 8.04598
40 3KFF ZBT 0.01218 0.41464 8.04598
41 1Y2F WAI 0.01404 0.41048 9.1954
42 4INI AMP 0.003076 0.42542 10.3448
43 4GLW NMN 0.02775 0.40941 10.3448
44 5BVB DOG 0.02358 0.4009 10.3448
45 2YIP YIO 0.008744 0.42887 11.4943
46 2ET1 GLV 0.01414 0.41394 11.4943
47 2PCU ASP 0.01159 0.41116 11.4943
48 3OV6 MK0 0.01351 0.40598 12.6437
49 1I7M PUT 0.03098 0.40251 12.6437
50 3DZ6 PUT 0.0178 0.40266 13.7931
51 2Z77 NCA 0.006995 0.42686 14.9425
52 1MJT ITU 0.01507 0.4221 14.9425
53 1GU3 BGC BGC BGC BGC BGC 0.01428 0.41114 14.9425
54 5OO5 UUA 0.008412 0.4017 16.092
55 4JGP PYR 0.01471 0.4117 18.3908
56 2BKK ADP 0.008377 0.40947 19.5402
57 3B00 16A 0.01223 0.40176 19.5402
58 5CEO 50D 0.003371 0.41551 22.9885
59 4XAC AKG 0.01095 0.41839 27.5862
Pocket No.: 2; Query (leader) PDB : 3ZW2; Ligand: NAG GAL FUC; Similar sites found: 36
This union binding pocket(no: 2) in the query (biounit: 3zw2.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4NS0 PIO 0.00117 0.46872 None
2 2BOS GLA GAL GLC 0.004882 0.42946 None
3 2BOS GLA GAL 0.004287 0.42172 None
4 5HV0 AKG 0.003041 0.4212 None
5 4M1U A2G MBG 0.01136 0.41991 None
6 5KEW 6SB 0.01192 0.41294 None
7 5F6U 5VK 0.02038 0.40907 None
8 4M26 AKG 0.01484 0.40865 None
9 5I8T LAC 0.01403 0.40749 None
10 3MTX PGT 0.01846 0.40746 None
11 2HZQ STR 0.004248 0.43595 2.29885
12 1Y9Q MED 0.008631 0.42015 2.29885
13 3JZ0 CLY 0.022 0.40206 2.29885
14 2DHC DCE 0.01279 0.40715 3.44828
15 4J25 OGA 0.006117 0.42666 4.5977
16 4YEE 4CQ 0.01312 0.41063 4.5977
17 1NJJ GET 0.008793 0.40848 4.5977
18 4FFG LBS 0.01094 0.40349 4.5977
19 5JSP DQY 0.01898 0.40246 4.5977
20 2FCU AKG 0.01013 0.41572 5.74713
21 3AVS OGA 0.01006 0.41006 5.74713
22 4GC1 MAN MAN 0.004149 0.40803 5.74713
23 1Y2F WAI 0.01641 0.40338 9.1954
24 4GQP B40 0.002503 0.44614 10.3448
25 5BVB DOG 0.0197 0.40264 10.3448
26 4IAW LIZ 0.01284 0.40066 10.3448
27 2OG7 SIN 0.006375 0.42737 11.4943
28 1REQ DCA 0.02891 0.40873 11.4943
29 2YIP YIO 0.01807 0.40685 11.4943
30 3I27 SID 0.01586 0.40481 11.4943
31 1I7M PUT 0.0269 0.40552 12.6437
32 4B1M FRU FRU 0.01679 0.40607 16.092
33 2OMN IPH 0.01309 0.41797 17.2414
34 5EVY SAL 0.01256 0.41186 17.2414
35 4RLT FSE 0.001116 0.44573 28.7356
36 2JIG PD2 0.005777 0.42181 33.3333
Pocket No.: 3; Query (leader) PDB : 3ZW2; Ligand: GAL FUC; Similar sites found: 33
This union binding pocket(no: 3) in the query (biounit: 3zw2.bio1) has 17 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4NS0 PIO 0.0008896 0.47389 None
2 4M1U A2G MBG 0.007809 0.42778 None
3 5HV0 AKG 0.001956 0.42354 None
4 2BOS GLA GAL 0.003908 0.42343 None
5 2BOS GLA GAL GLC 0.00441 0.41808 None
6 3MTX PGT 0.01575 0.41446 None
7 4M26 AKG 0.01472 0.40653 None
8 5KEW 6SB 0.01556 0.40498 None
9 1X0P FAD 0.009917 0.40189 None
10 5F6U 5VK 0.02516 0.40157 None
11 5I8T LAC 0.01725 0.40081 None
12 2HZQ STR 0.009219 0.41598 2.29885
13 1OI6 TMP 0.0119 0.4129 2.29885
14 3A16 PXO 0.02337 0.40717 3.44828
15 4J25 OGA 0.00608 0.42445 4.5977
16 1NJJ GET 0.007219 0.41026 4.5977
17 4FFG LBS 0.008933 0.40896 4.5977
18 4YEE 4CQ 0.01604 0.40366 4.5977
19 1Y7P RIP 0.005556 0.41919 5.74713
20 3AVS OGA 0.009301 0.40948 5.74713
21 4GJY OGA 0.01576 0.40712 8.04598
22 4IAW LIZ 0.004803 0.42336 10.3448
23 4JE5 PMP 0.009086 0.40555 10.3448
24 4JE5 PLP 0.009861 0.40387 10.3448
25 1REQ DCA 0.02891 0.41208 11.4943
26 3I27 SID 0.01276 0.40734 11.4943
27 2OG7 SIN 0.01569 0.40229 11.4943
28 1I7M PUT 0.02456 0.40791 12.6437
29 4N14 WR7 0.008134 0.41121 14.9425
30 4B1M FRU FRU 0.01391 0.40844 16.092
31 2OMN IPH 0.02072 0.40101 17.2414
32 2JIG PD2 0.005396 0.42092 33.3333
33 4K55 H6P 0.0104 0.40475 36.7816
Pocket No.: 4; Query (leader) PDB : 3ZW2; Ligand: NAG GAL FUC; Similar sites found: 46
This union binding pocket(no: 4) in the query (biounit: 3zw2.bio1) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1DZT ATY 0.001971 0.45123 None
2 4XCB AKG 0.004258 0.42854 None
3 4DSU BZI 0.007011 0.42337 None
4 4CQK PIO 0.01282 0.40573 None
5 1DZT TPE 0.01819 0.40321 None
6 5H9P TD2 0.01551 0.40081 None
7 5GZ9 MAN 0.00864 0.40324 2.29885
8 4XBA 5GP 0.00408 0.40271 2.29885
9 3GC0 AMP 0.003437 0.41491 3.44828
10 5KWY C3S 0.002586 0.40623 3.44828
11 3VV1 GAL FUC 0.008082 0.40365 3.44828
12 4G05 JZ3 0.01469 0.42533 4.5977
13 4FFG 0U8 0.009749 0.42054 4.5977
14 4AZT LY2 0.005546 0.41319 4.5977
15 3N1S 5GP 0.001496 0.43087 5.04202
16 5DBX ANP 0.002096 0.42472 5.74713
17 3X01 AMP 0.006422 0.42174 5.74713
18 1XK5 TPG 0.009344 0.41673 5.74713
19 1Y7P RIP 0.01044 0.41283 5.74713
20 3WXL ADP 0.01037 0.40341 5.74713
21 3E7S AT2 0.01542 0.40063 5.74713
22 1AV5 AP2 0.0006361 0.44689 6.89655
23 5CX6 CDP 0.01389 0.40501 6.89655
24 2BO4 FLC 0.01878 0.40217 6.89655
25 4X17 SIA SIA 0.01242 0.40105 6.89655
26 3QRC SCR 0.0005003 0.46038 8.04598
27 4L3L 5FI 0.01001 0.42583 8.04598
28 1S68 AMP 0.005575 0.42277 8.04598
29 3H9R TAK 0.006383 0.41494 8.04598
30 2WQP WQP 0.02295 0.40503 8.04598
31 4A91 GLU 0.001858 0.43572 9.1954
32 5J75 6GQ 0.004115 0.40207 9.1954
33 4INI AMP 0.001445 0.42293 10.3448
34 3OZV FAD 0.02269 0.42206 10.3448
35 5KO1 6UY 0.002292 0.40705 10.3448
36 4GLW NMN 0.02142 0.40614 10.3448
37 5KJW 53C 0.01422 0.406 10.3448
38 3OV6 MK0 0.01273 0.42183 12.6437
39 1JL0 PUT 0.008497 0.41962 13.7931
40 1MJT ITU 0.01791 0.40566 14.9425
41 2Z77 NCA 0.01347 0.40384 14.9425
42 3ZOK NAD 0.03305 0.40186 16.092
43 4JGP PYR 0.006161 0.42248 18.3908
44 4EIP FAD 0.04269 0.40823 21.8391
45 5CEO 50D 0.001445 0.45028 22.9885
46 4XAC AKG 0.01027 0.41136 27.5862
Pocket No.: 5; Query (leader) PDB : 3ZW2; Ligand: NAG GAL FUC; Similar sites found: 19
This union binding pocket(no: 5) in the query (biounit: 3zw2.bio1) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2QL9 CIT 0.006672 0.41761 None
2 2HKA C3S 0.000957 0.40504 None
3 4MJ0 SIA SIA GAL 0.01499 0.40235 None
4 4QM9 CYS 0.01681 0.40123 None
5 1OI6 TMP 0.00931 0.41786 2.29885
6 3OID TCL 0.00984 0.41059 3.44828
7 4FE2 ASP 0.0101 0.40829 4.5977
8 1OIK AKG 0.009907 0.41101 5.74713
9 3RGA LSB 0.002731 0.40662 5.74713
10 3AGC RCC 0.02378 0.40425 6.89655
11 4LED XXR 0.002075 0.43018 8.04598
12 4CJN QNZ 0.01581 0.40808 8.04598
13 4BPZ GLC BGC BGC 0.01195 0.40185 10.3448
14 2ET1 GLV 0.009513 0.41415 11.4943
15 2PCU ASP 0.008545 0.40886 11.4943
16 2JBM SRT 0.02494 0.41285 14.9425
17 5OO5 UUA 0.002497 0.40766 16.092
18 3B00 16A 0.006172 0.4046 19.5402
19 4K55 H6P 0.004409 0.42129 36.7816
Pocket No.: 6; Query (leader) PDB : 3ZW2; Ligand: NAG GAL FUC; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 3zw2.bio1) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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