Receptor
PDB id Resolution Class Description Source Keywords
3fu6 2.05 Å EC: 3.3.2.6 LEUKOTRIENE A4 HYDROLASE IN COMPLEX WITH FRAGMENT (4-THIOPHE YLPHENYL)METHANAMINE HOMO SAPIENS LEUKOTRIENE A4 HYDROLASE LTA4H FRAGMENT CRYSTALLOGRAPHY FOF LIFE FOL ALTERNATIVE SPLICING CYTOPLASM HYDROLASE LEUKOTRIENE BIOSYNTHESIS METAL-BINDING METALLOPROTEASE MULTIFUNCTIONAL ENZYME POLYMORPHISM PROTEASE ZINC
Ref.: DISCOVERY OF LEUKOTRIENE A4 HYDROLASE INHIBITORS US METABOLOMICS BIASED FRAGMENT CRYSTALLOGRAPHY. J.MED.CHEM. V. 52 4694 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
80G A:710;
 Valid;
 none;
 ic50 = 106 uM
189.277 C11 H11 N S c1cc(...
ACT A:801;
A:802;
 Invalid;
Invalid;
 none;
none;
 submit data
59.044 C2 H3 O2 CC(=O...
IMD A:803;
A:804;
 Invalid;
Invalid;
 none;
none;
 submit data
69.085 C3 H5 N2 c1c[n...
YB A:702;
 Invalid;
 none;
 submit data
173.04 Yb [Yb+3...
ZN A:701;
 Part of Protein;
 none;
 submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2VJ8 1.8 Å EC: 3.3.2.6 COMPLEX OF HUMAN LEUKOTRIENE A4 HYDROLASE WITH A HYDROXAMIC INHIBITOR HOMO SAPIENS HYDROXAMIC ACID LEUKOTRIENE HYDROLASE ZINC PROTEASE HYDRMETALLOPROTEASE
Ref.: CRYSTAL STRUCTURES OF LEUKOTRIENE A4 HYDROLASE IN C WITH CAPTOPRIL AND TWO COMPETITIVE TIGHT-BINDING IN FASEB J. V. 16 1648 2002
Members (48)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 3FTW - 11X C12 H12 N2 c1ccc(cc1)....
2 3FUK ic50 = 966 uM 58Z C16 H20 N2 O3 c1cc2c(cc[....
3 3FU6 ic50 = 106 uM 80G C11 H11 N S c1cc(sc1)c....
4 6END ic50 = 0.133 uM BGK C13 H8 N2 O2 S c1cc2c(nc1....
5 3FUI ic50 = 0.157 uM 812 C18 H22 N2 O c1ccc(cc1)....
6 3FU5 ic50 = 75.2 uM 492 C9 H9 N S2 c1cc(sc1)c....
7 2R59 Ki = 6.5 nM PH0 C27 H31 N2 O5 P c1ccc(cc1)....
8 5N3W ic50 = 0.5 uM 8KW C15 H16 O3 COc1cc(cc(....
9 3CHP ic50 = 5400 nM 4BO C17 H18 N2 O4 c1ccc(cc1)....
10 4L2L Ki = 2.3 uM 1V6 C16 H14 N2 S c1ccc(cc1)....
11 1HS6 - BES C16 H24 N2 O4 CC(C)C[C@@....
12 6ENB - PRO GLY PRO n/a n/a
13 3B7T - ARG ALA ARG n/a n/a
14 3B7R Ki = 20 nM BIR C21 H27 N2 O5 P C[C@@H](C(....
15 3FUN ic50 = 0.189 uM 798 C22 H21 N O2 S c1cc(ccc1c....
16 3FTX - BES C16 H24 N2 O4 CC(C)C[C@@....
17 5NI4 - DJ3 C20 H30 O3 CCCCC/C=CC....
18 3CHR ic50 = 61 nM 4BS C17 H20 N2 O2 c1ccc(cc1)....
19 3B7S - ARG SER ARG n/a n/a
20 2VJ8 Ki = 0.002 uM HA2 C22 H28 N2 O5 c1ccc(cc1)....
21 3FUH - BES C16 H24 N2 O4 CC(C)C[C@@....
22 5AEN ic50 = 0.06 uM DP8 C16 H19 N O2 CN(C)CCOc1....
23 4MS6 - 28T C13 H20 N2 O4 C1C[C@H](N....
24 3FUE ic50 = 1510 uM 11S C8 H6 Cl N c1cc2c(cc[....
25 3FH8 ic50 = 180 nM 27P C19 H23 N O c1ccc(cc1)....
26 5BPP ic50 = 15.86 uM A4Z C12 H17 N O3 CCCCOc1ccc....
27 3FTZ - 848 C12 H12 N2 O c1ccc(c(c1....
28 5NI6 - DJ3 C20 H30 O3 CCCCC/C=CC....
29 3FTV ic50 = 1667 uM 11X C12 H12 N2 c1ccc(cc1)....
30 3CHQ ic50 = 20 nM 4BQ C18 H20 N2 O4 c1ccc(cc1)....
31 3FUL ic50 = 199 uM 52D C18 H20 N2 O2 c1cc(ccc1C....
32 3FTS ic50 = 212 uM STL C14 H12 O3 c1cc(ccc1C....
33 3FHE - 28P C20 H25 N O3 C[N@@](CCC....
34 6ENC ic50 = 0.019 uM BGW C20 H20 N2 O3 S c1ccc2c(c1....
35 3FUM ic50 = 170 uM 80A C18 H22 N2 O2 c1cc(ccc1[....
36 3B7U - KEL C14 H18 N2 O5 C[C@@H](C(....
37 3FTY ic50 = 619 uM 3IP C12 H12 N2 O c1ccc(cc1)....
38 3FTU ic50 = 247 uM RE2 C14 H14 O3 c1cc(ccc1C....
39 3FH7 Kd = 25 nM 25P C21 H23 Cl N O4 c1cc(ccc1O....
40 3FUJ ic50 = 234 uM 00G C14 H14 N2 O c1ccn(c1)C....
41 3FU0 ic50 = 5308 uM 22F C12 H8 F N O c1cc(ccc1C....
42 3FH5 ic50 = 87 nM 24P C18 H21 N O c1ccc(cc1)....
43 3CHO ic50 = 280 nM 4BG C15 H16 N2 O2 c1ccc(cc1)....
44 3FUD ic50 > 2000 uM 692 C12 H13 N S CNCc1ccccc....
45 3FU3 ic50 = 1443 uM 92G C9 H8 N2 O S c1cc(ccc1c....
46 4MKT Ki = 2.3 uM 1V6 C16 H14 N2 S c1ccc(cc1)....
47 5NI2 - DJ3 C20 H30 O3 CCCCC/C=CC....
48 1GW6 - BES C16 H24 N2 O4 CC(C)C[C@@....
70% Homology Family (49)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 3FTW - 11X C12 H12 N2 c1ccc(cc1)....
2 3FUK ic50 = 966 uM 58Z C16 H20 N2 O3 c1cc2c(cc[....
3 3FU6 ic50 = 106 uM 80G C11 H11 N S c1cc(sc1)c....
4 6END ic50 = 0.133 uM BGK C13 H8 N2 O2 S c1cc2c(nc1....
5 3FUI ic50 = 0.157 uM 812 C18 H22 N2 O c1ccc(cc1)....
6 3FU5 ic50 = 75.2 uM 492 C9 H9 N S2 c1cc(sc1)c....
7 2R59 Ki = 6.5 nM PH0 C27 H31 N2 O5 P c1ccc(cc1)....
8 5N3W ic50 = 0.5 uM 8KW C15 H16 O3 COc1cc(cc(....
9 3CHP ic50 = 5400 nM 4BO C17 H18 N2 O4 c1ccc(cc1)....
10 4L2L Ki = 2.3 uM 1V6 C16 H14 N2 S c1ccc(cc1)....
11 1HS6 - BES C16 H24 N2 O4 CC(C)C[C@@....
12 6ENB - PRO GLY PRO n/a n/a
13 3B7T - ARG ALA ARG n/a n/a
14 3B7R Ki = 20 nM BIR C21 H27 N2 O5 P C[C@@H](C(....
15 3FUN ic50 = 0.189 uM 798 C22 H21 N O2 S c1cc(ccc1c....
16 3FTX - BES C16 H24 N2 O4 CC(C)C[C@@....
17 5NI4 - DJ3 C20 H30 O3 CCCCC/C=CC....
18 3CHR ic50 = 61 nM 4BS C17 H20 N2 O2 c1ccc(cc1)....
19 3B7S - ARG SER ARG n/a n/a
20 2VJ8 Ki = 0.002 uM HA2 C22 H28 N2 O5 c1ccc(cc1)....
21 3FUH - BES C16 H24 N2 O4 CC(C)C[C@@....
22 5AEN ic50 = 0.06 uM DP8 C16 H19 N O2 CN(C)CCOc1....
23 4MS6 - 28T C13 H20 N2 O4 C1C[C@H](N....
24 3FUE ic50 = 1510 uM 11S C8 H6 Cl N c1cc2c(cc[....
25 3FH8 ic50 = 180 nM 27P C19 H23 N O c1ccc(cc1)....
26 5BPP ic50 = 15.86 uM A4Z C12 H17 N O3 CCCCOc1ccc....
27 3FTZ - 848 C12 H12 N2 O c1ccc(c(c1....
28 5NI6 - DJ3 C20 H30 O3 CCCCC/C=CC....
29 3FTV ic50 = 1667 uM 11X C12 H12 N2 c1ccc(cc1)....
30 3CHQ ic50 = 20 nM 4BQ C18 H20 N2 O4 c1ccc(cc1)....
31 3FUL ic50 = 199 uM 52D C18 H20 N2 O2 c1cc(ccc1C....
32 3FTS ic50 = 212 uM STL C14 H12 O3 c1cc(ccc1C....
33 3FHE - 28P C20 H25 N O3 C[N@@](CCC....
34 6ENC ic50 = 0.019 uM BGW C20 H20 N2 O3 S c1ccc2c(c1....
35 3FUM ic50 = 170 uM 80A C18 H22 N2 O2 c1cc(ccc1[....
36 3B7U - KEL C14 H18 N2 O5 C[C@@H](C(....
37 3FTY ic50 = 619 uM 3IP C12 H12 N2 O c1ccc(cc1)....
38 3FTU ic50 = 247 uM RE2 C14 H14 O3 c1cc(ccc1C....
39 3FH7 Kd = 25 nM 25P C21 H23 Cl N O4 c1cc(ccc1O....
40 3FUJ ic50 = 234 uM 00G C14 H14 N2 O c1ccn(c1)C....
41 3FU0 ic50 = 5308 uM 22F C12 H8 F N O c1cc(ccc1C....
42 3FH5 ic50 = 87 nM 24P C18 H21 N O c1ccc(cc1)....
43 3CHO ic50 = 280 nM 4BG C15 H16 N2 O2 c1ccc(cc1)....
44 3FUD ic50 > 2000 uM 692 C12 H13 N S CNCc1ccccc....
45 3FU3 ic50 = 1443 uM 92G C9 H8 N2 O S c1cc(ccc1c....
46 4MKT Ki = 2.3 uM 1V6 C16 H14 N2 S c1ccc(cc1)....
47 5NI2 - DJ3 C20 H30 O3 CCCCC/C=CC....
48 1GW6 - BES C16 H24 N2 O4 CC(C)C[C@@....
49 4GAA - BES C16 H24 N2 O4 CC(C)C[C@@....
50% Homology Family (50)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3FTW - 11X C12 H12 N2 c1ccc(cc1)....
2 3FUK ic50 = 966 uM 58Z C16 H20 N2 O3 c1cc2c(cc[....
3 3FU6 ic50 = 106 uM 80G C11 H11 N S c1cc(sc1)c....
4 6END ic50 = 0.133 uM BGK C13 H8 N2 O2 S c1cc2c(nc1....
5 3FUI ic50 = 0.157 uM 812 C18 H22 N2 O c1ccc(cc1)....
6 3FU5 ic50 = 75.2 uM 492 C9 H9 N S2 c1cc(sc1)c....
7 2R59 Ki = 6.5 nM PH0 C27 H31 N2 O5 P c1ccc(cc1)....
8 5N3W ic50 = 0.5 uM 8KW C15 H16 O3 COc1cc(cc(....
9 3CHP ic50 = 5400 nM 4BO C17 H18 N2 O4 c1ccc(cc1)....
10 4L2L Ki = 2.3 uM 1V6 C16 H14 N2 S c1ccc(cc1)....
11 1HS6 - BES C16 H24 N2 O4 CC(C)C[C@@....
12 6ENB - PRO GLY PRO n/a n/a
13 3B7T - ARG ALA ARG n/a n/a
14 3B7R Ki = 20 nM BIR C21 H27 N2 O5 P C[C@@H](C(....
15 3FUN ic50 = 0.189 uM 798 C22 H21 N O2 S c1cc(ccc1c....
16 3FTX - BES C16 H24 N2 O4 CC(C)C[C@@....
17 5NI4 - DJ3 C20 H30 O3 CCCCC/C=CC....
18 3CHR ic50 = 61 nM 4BS C17 H20 N2 O2 c1ccc(cc1)....
19 3B7S - ARG SER ARG n/a n/a
20 2VJ8 Ki = 0.002 uM HA2 C22 H28 N2 O5 c1ccc(cc1)....
21 3FUH - BES C16 H24 N2 O4 CC(C)C[C@@....
22 5AEN ic50 = 0.06 uM DP8 C16 H19 N O2 CN(C)CCOc1....
23 4MS6 - 28T C13 H20 N2 O4 C1C[C@H](N....
24 3FUE ic50 = 1510 uM 11S C8 H6 Cl N c1cc2c(cc[....
25 3FH8 ic50 = 180 nM 27P C19 H23 N O c1ccc(cc1)....
26 5BPP ic50 = 15.86 uM A4Z C12 H17 N O3 CCCCOc1ccc....
27 3FTZ - 848 C12 H12 N2 O c1ccc(c(c1....
28 5NI6 - DJ3 C20 H30 O3 CCCCC/C=CC....
29 3FTV ic50 = 1667 uM 11X C12 H12 N2 c1ccc(cc1)....
30 3CHQ ic50 = 20 nM 4BQ C18 H20 N2 O4 c1ccc(cc1)....
31 3FUL ic50 = 199 uM 52D C18 H20 N2 O2 c1cc(ccc1C....
32 3FTS ic50 = 212 uM STL C14 H12 O3 c1cc(ccc1C....
33 3FHE - 28P C20 H25 N O3 C[N@@](CCC....
34 6ENC ic50 = 0.019 uM BGW C20 H20 N2 O3 S c1ccc2c(c1....
35 3FUM ic50 = 170 uM 80A C18 H22 N2 O2 c1cc(ccc1[....
36 3B7U - KEL C14 H18 N2 O5 C[C@@H](C(....
37 3FTY ic50 = 619 uM 3IP C12 H12 N2 O c1ccc(cc1)....
38 3FTU ic50 = 247 uM RE2 C14 H14 O3 c1cc(ccc1C....
39 3FH7 Kd = 25 nM 25P C21 H23 Cl N O4 c1cc(ccc1O....
40 3FUJ ic50 = 234 uM 00G C14 H14 N2 O c1ccn(c1)C....
41 3FU0 ic50 = 5308 uM 22F C12 H8 F N O c1cc(ccc1C....
42 3FH5 ic50 = 87 nM 24P C18 H21 N O c1ccc(cc1)....
43 3CHO ic50 = 280 nM 4BG C15 H16 N2 O2 c1ccc(cc1)....
44 3FUD ic50 > 2000 uM 692 C12 H13 N S CNCc1ccccc....
45 3FU3 ic50 = 1443 uM 92G C9 H8 N2 O S c1cc(ccc1c....
46 4MKT Ki = 2.3 uM 1V6 C16 H14 N2 S c1ccc(cc1)....
47 5NI2 - DJ3 C20 H30 O3 CCCCC/C=CC....
48 1GW6 - BES C16 H24 N2 O4 CC(C)C[C@@....
49 4GAA - BES C16 H24 N2 O4 CC(C)C[C@@....
50 2XQ0 - BES C16 H24 N2 O4 CC(C)C[C@@....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 80G; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 80G 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: 80G; Similar ligands found: 527
No: Ligand Similarity coefficient
1 JAH 0.9792
2 F4K 0.9739
3 2QC 0.9716
4 SWX 0.9698
5 CPZ 0.9648
6 36Y 0.9648
7 54E 0.9579
8 A5E 0.9575
9 MSR 0.9557
10 6SD 0.9543
11 5TT 0.9533
12 PH3 0.9532
13 OQC 0.9530
14 92G 0.9529
15 PQS 0.9478
16 C53 0.9469
17 SNU 0.9467
18 GVY 0.9450
19 FMQ 0.9420
20 TZF 0.9408
21 6P3 0.9405
22 RA7 0.9400
23 LO1 0.9396
24 P81 0.9381
25 VC3 0.9379
26 HC4 0.9378
27 HNH 0.9371
28 492 0.9370
29 3VS 0.9362
30 AWE 0.9345
31 RKN 0.9339
32 XCG 0.9329
33 TYR 0.9319
34 LR8 0.9309
35 L15 0.9301
36 FZM 0.9298
37 5LA 0.9295
38 N4E 0.9289
39 BP7 0.9288
40 FYR 0.9287
41 TYL 0.9287
42 K4V 0.9283
43 50C 0.9282
44 PQM 0.9279
45 C1M 0.9264
46 EE8 0.9260
47 C82 0.9258
48 I3E 0.9257
49 JA5 0.9254
50 JBZ 0.9253
51 0NX 0.9250
52 613 0.9243
53 363 0.9237
54 TMG 0.9237
55 HNK 0.9228
56 KLS 0.9227
57 X48 0.9225
58 9FH 0.9221
59 S7S 0.9221
60 HNL 0.9220
61 1A5 0.9218
62 UNJ 0.9216
63 KTJ 0.9212
64 72D 0.9210
65 1Z6 0.9208
66 D2G 0.9203
67 A4N 0.9202
68 5O6 0.9201
69 TID 0.9190
70 9NB 0.9190
71 HPP 0.9188
72 A5Q 0.9185
73 TYC 0.9183
74 DTY 0.9179
75 HXY 0.9178
76 BNL 0.9177
77 6KT 0.9175
78 5OO 0.9167
79 3ZB 0.9159
80 SNV 0.9155
81 EN1 0.9152
82 AU8 0.9140
83 A6Z 0.9139
84 3VQ 0.9132
85 G14 0.9129
86 TYE 0.9128
87 8NB 0.9128
88 A7H 0.9123
89 HDH 0.9123
90 ENO 0.9120
91 PPY 0.9120
92 4FE 0.9119
93 NAG 0.9116
94 GO2 0.9116
95 QBP 0.9115
96 DVQ 0.9112
97 OTR 0.9111
98 J9N 0.9110
99 RNO 0.9109
100 QME 0.9109
101 HNT 0.9108
102 8D6 0.9103
103 4FC 0.9098
104 4HB 0.9097
105 4I8 0.9092
106 A9K 0.9092
107 OHJ 0.9091
108 GB5 0.9090
109 88L 0.9088
110 94W 0.9086
111 8V8 0.9084
112 X0U 0.9079
113 XIZ 0.9077
114 SNO 0.9076
115 PFF 0.9075
116 6FB 0.9074
117 QIV 0.9074
118 7O4 0.9068
119 CK2 0.9067
120 2PK 0.9067
121 DHC 0.9066
122 LZ5 0.9065
123 7MW 0.9064
124 BZ2 0.9062
125 E3X 0.9061
126 S0D 0.9058
127 ODK 0.9057
128 HX4 0.9057
129 4BZ 0.9057
130 EQW 0.9056
131 F4E 0.9053
132 CFA 0.9053
133 4CF 0.9052
134 2PV 0.9051
135 4NM 0.9047
136 NY4 0.9046
137 4BY 0.9046
138 KLE 0.9044
139 A7N 0.9039
140 F90 0.9037
141 2BX 0.9036
142 R9J 0.9034
143 4BF 0.9033
144 4AF 0.9032
145 PHI 0.9032
146 UA5 0.9026
147 GT4 0.9025
148 0BP 0.9025
149 AMH 0.9024
150 CH9 0.9023
151 JMG 0.9022
152 PNZ 0.9022
153 K3D 0.9020
154 PNP 0.9020
155 4NP 0.9018
156 SQ4 0.9018
157 ALE 0.9017
158 HWD 0.9016
159 CWJ 0.9014
160 SQ7 0.9014
161 PUE 0.9014
162 7VP 0.9012
163 ICB 0.9012
164 IWT 0.9012
165 BFL 0.9006
166 TCA 0.9003
167 2FX 0.9001
168 Y3L 0.9000
169 J6W 0.8998
170 L03 0.8997
171 DAH 0.8995
172 PO6 0.8990
173 BRH 0.8986
174 AOT 0.8984
175 6ZX 0.8984
176 ESX 0.8982
177 HL4 0.8981
178 M1T 0.8980
179 4FP 0.8975
180 K82 0.8973
181 PJW 0.8973
182 6FZ 0.8970
183 NK5 0.8970
184 4FA 0.8968
185 657 0.8967
186 B1J 0.8963
187 AES 0.8963
188 1F1 0.8960
189 K80 0.8960
190 ZZA 0.8960
191 7FU 0.8959
192 7N8 0.8959
193 YPN 0.8958
194 IS2 0.8956
195 GWM 0.8954
196 4BL 0.8947
197 RKV 0.8946
198 K7H 0.8944
199 I2E 0.8940
200 PIM 0.8940
201 BVA 0.8938
202 JRB 0.8938
203 BQ2 0.8931
204 KDG 0.8929
205 S0E 0.8928
206 CXH 0.8926
207 LJ3 0.8926
208 3W8 0.8924
209 S0W 0.8923
210 LNR 0.8922
211 1FD 0.8921
212 4JC 0.8921
213 XDK 0.8919
214 NGA 0.8918
215 ZEC 0.8918
216 FTV 0.8918
217 64Z 0.8916
218 3VX 0.8916
219 BX4 0.8914
220 JCZ 0.8914
221 DE5 0.8913
222 LOT 0.8912
223 PCS 0.8912
224 HHH 0.8911
225 4LW 0.8910
226 IYR 0.8907
227 E5X 0.8907
228 9R5 0.8905
229 BVS 0.8904
230 E4P 0.8904
231 GVG 0.8902
232 2O8 0.8901
233 BPN 0.8900
234 4LV 0.8900
235 X6W 0.8897
236 4MB 0.8892
237 M3H 0.8891
238 AMS 0.8891
239 0UL 0.8889
240 3W6 0.8887
241 MPK 0.8887
242 AN3 0.8886
243 3W3 0.8886
244 AEG 0.8886
245 4YO 0.8886
246 LQ2 0.8883
247 PHE 0.8883
248 M4N 0.8883
249 5H6 0.8879
250 12T 0.8878
251 ANN 0.8878
252 SOJ 0.8877
253 6NT 0.8877
254 5RP 0.8875
255 4JE 0.8874
256 MP5 0.8872
257 36M 0.8872
258 SQV 0.8869
259 4NS 0.8869
260 YRL 0.8869
261 4WL 0.8868
262 FHC 0.8866
263 L14 0.8864
264 3A9 0.8864
265 OOG 0.8864
266 EZL 0.8863
267 KBZ 0.8863
268 68B 0.8859
269 4NB 0.8858
270 27K 0.8858
271 0HN 0.8857
272 YE6 0.8856
273 ERZ 0.8855
274 R20 0.8855
275 N9J 0.8854
276 0ON 0.8854
277 GB4 0.8852
278 J9Q 0.8852
279 1OS 0.8851
280 P7Y 0.8851
281 428 0.8851
282 ODO 0.8850
283 KF5 0.8850
284 EUE 0.8847
285 MTL 0.8845
286 NFM 0.8844
287 2HC 0.8843
288 PIY 0.8843
289 26C 0.8838
290 86L 0.8837
291 1EB 0.8835
292 1A7 0.8835
293 AZM 0.8834
294 IPO 0.8832
295 L99 0.8832
296 2D2 0.8831
297 833 0.8831
298 AJ1 0.8831
299 E7S 0.8830
300 YI6 0.8829
301 1L5 0.8829
302 D9Z 0.8828
303 FDR 0.8827
304 GF4 0.8825
305 KW7 0.8823
306 MS9 0.8821
307 AEF 0.8820
308 SSC 0.8814
309 A5P 0.8814
310 NDD 0.8812
311 15E 0.8811
312 0HO 0.8810
313 9ZE 0.8808
314 4P5 0.8807
315 OLU 0.8806
316 BPY 0.8805
317 SN4 0.8802
318 SYD 0.8801
319 0OK 0.8801
320 FBF 0.8801
321 3R4 0.8799
322 J1K 0.8799
323 AAN 0.8797
324 AKG 0.8797
325 ZYX 0.8795
326 RYV 0.8795
327 GOE 0.8794
328 ENW 0.8791
329 MPV 0.8791
330 PRL 0.8790
331 52C 0.8789
332 4HP 0.8789
333 KMY 0.8788
334 ABI 0.8788
335 5TY 0.8786
336 SJK 0.8784
337 L13 0.8783
338 3XR 0.8782
339 PLP 0.8782
340 2ZM 0.8779
341 4JQ 0.8776
342 F02 0.8775
343 YZM 0.8775
344 NCT 0.8775
345 1X4 0.8770
346 DEZ 0.8769
347 HRM 0.8767
348 DDU 0.8765
349 EUH 0.8762
350 2FY 0.8762
351 PTB 0.8762
352 NFA 0.8760
353 FF2 0.8760
354 AM4 0.8759
355 PBZ 0.8758
356 H75 0.8757
357 AJG 0.8754
358 NF3 0.8753
359 L22 0.8753
360 259 0.8753
361 HFA 0.8750
362 S0A 0.8750
363 N91 0.8749
364 61M 0.8749
365 M45 0.8747
366 42J 0.8746
367 9FL 0.8746
368 LLH 0.8745
369 HHS 0.8745
370 2J1 0.8742
371 36E 0.8739
372 6MW 0.8739
373 MQN 0.8738
374 EVF 0.8738
375 CS2 0.8736
376 JB8 0.8736
377 M4S 0.8736
378 NFZ 0.8735
379 H4B 0.8735
380 92O 0.8733
381 7EH 0.8732
382 L1T 0.8732
383 AHN 0.8732
384 TT4 0.8732
385 2JX 0.8731
386 HCI 0.8731
387 N2Z 0.8730
388 LDP 0.8730
389 97T 0.8728
390 MXD 0.8727
391 W29 0.8727
392 8WO 0.8724
393 M28 0.8724
394 OA1 0.8723
395 0OO 0.8723
396 HL6 0.8722
397 HIS 0.8722
398 LGT 0.8719
399 1KN 0.8719
400 TIH 0.8716
401 1PS 0.8716
402 0F3 0.8716
403 HQJ 0.8716
404 OGA 0.8714
405 4CM 0.8714
406 ITE 0.8713
407 LR5 0.8713
408 1VK 0.8712
409 5VL 0.8712
410 RES 0.8710
411 15N 0.8710
412 ST3 0.8709
413 P9E 0.8708
414 6C5 0.8708
415 1BW 0.8707
416 NDG 0.8707
417 PZM 0.8707
418 3VW 0.8706
419 6J5 0.8704
420 1WC 0.8702
421 P7V 0.8701
422 DZA 0.8701
423 THU 0.8699
424 A2G 0.8697
425 6NI 0.8695
426 Z13 0.8694
427 ZRK 0.8694
428 HBD 0.8692
429 78Y 0.8692
430 D8Q 0.8692
431 MMS 0.8689
432 0JD 0.8689
433 SSB 0.8688
434 FLP 0.8688
435 4ZA 0.8688
436 Q06 0.8688
437 TRP 0.8684
438 JDN 0.8684
439 68A 0.8680
440 3NY 0.8680
441 FCW 0.8679
442 650 0.8679
443 M5H 0.8678
444 6HO 0.8677
445 N3W 0.8675
446 JGB 0.8675
447 P80 0.8674
448 BZJ 0.8673
449 M78 0.8671
450 TB8 0.8668
451 LL1 0.8668
452 HHI 0.8666
453 5NI 0.8663
454 A51 0.8663
455 2B4 0.8662
456 549 0.8662
457 S2G 0.8662
458 J27 0.8661
459 3AE 0.8660
460 2WU 0.8659
461 5B2 0.8657
462 K97 0.8654
463 FCD 0.8651
464 5SP 0.8650
465 RUY 0.8648
466 E1T 0.8648
467 2HG 0.8648
468 2K8 0.8645
469 IOS 0.8642
470 ZHA 0.8642
471 STX 0.8640
472 MD6 0.8639
473 8ZE 0.8636
474 H2B 0.8631
475 BZQ 0.8631
476 BNX 0.8629
477 4NZ 0.8628
478 S7J 0.8627
479 AMR 0.8627
480 HBO 0.8625
481 GGB 0.8625
482 SOR 0.8624
483 4AB 0.8622
484 Z82 0.8622
485 4MP 0.8620
486 6TZ 0.8617
487 RQD 0.8616
488 FER 0.8614
489 4BX 0.8614
490 A7K 0.8611
491 0SY 0.8611
492 IAC 0.8604
493 CC5 0.8603
494 SKF 0.8603
495 4CN 0.8602
496 TOH 0.8602
497 GLO 0.8601
498 S2P 0.8599
499 BBK 0.8595
500 4XF 0.8593
501 28A 0.8591
502 ARG 0.8590
503 CCU 0.8590
504 Y0V 0.8583
505 2LT 0.8582
506 N7I 0.8581
507 TJM 0.8580
508 JFS 0.8578
509 GDL 0.8577
510 0FR 0.8577
511 GLU 0.8577
512 8U3 0.8576
513 9H2 0.8574
514 DRG 0.8573
515 A9B 0.8573
516 1Q1 0.8571
517 4V2 0.8569
518 HJ7 0.8563
519 6C8 0.8561
520 6DQ 0.8560
521 DER 0.8558
522 P4L 0.8549
523 M4T 0.8548
524 D3G 0.8544
525 CBE 0.8543
526 54Z 0.8542
527 RP3 0.8515
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2VJ8; Ligand: HA2; Similar sites found with APoc: 1
This union binding pocket(no: 1) in the query (biounit: 2vj8.bio1) has 40 residues
No: Leader PDB Ligand Sequence Similarity
1 6Q4R HJ5 24.5499
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