Receptor
PDB id Resolution Class Description Source Keywords
3lgf 1.5 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF THE 53BP1 TANDEM TUDOR DOMAIN IN COMPLE P53K370ME2 HOMO SAPIENS TANDEM TUDOR DOMAINS DIMETHYLATED P53 PEPTIDE DNA REPAIR CYCLE DNA DAMAGE DNA-BINDING METHYLATION TRANSCRIPTIONTRANSCRIPTION REGULATION
Ref.: STRUCTURAL INSIGHT INTO P53 RECOGNITION BY THE 53BP TUDOR DOMAIN. J.MOL.BIOL. V. 398 489 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PGE A:201;
A:202;
 Invalid;
Invalid;
 none;
none;
 submit data
150.173 C6 H14 O4 C(COC...
SER SER HIS LEU MLY SER LYS LYS GLY GLN B:370;
 Valid;
 none;
 submit data
160.261 n/a O=CC(...
SO4 A:203;
 Invalid;
 none;
 submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3LGF 1.5 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF THE 53BP1 TANDEM TUDOR DOMAIN IN COMPLE P53K370ME2 HOMO SAPIENS TANDEM TUDOR DOMAINS DIMETHYLATED P53 PEPTIDE DNA REPAIR CYCLE DNA DAMAGE DNA-BINDING METHYLATION TRANSCRIPTIONTRANSCRIPTION REGULATION
Ref.: STRUCTURAL INSIGHT INTO P53 RECOGNITION BY THE 53BP TUDOR DOMAIN. J.MOL.BIOL. V. 398 489 2010
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 552 families.
1 3LGF - SER SER HIS LEU MLY SER LYS LYS GLY GLN n/a n/a
2 2IG0 - LYS ARG HIS ARG MLY VAL LEU ARG ASP ASN n/a n/a
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 426 families.
1 3LGF - SER SER HIS LEU MLY SER LYS LYS GLY GLN n/a n/a
2 2IG0 - LYS ARG HIS ARG MLY VAL LEU ARG ASP ASN n/a n/a
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 322 families.
1 3LGF - SER SER HIS LEU MLY SER LYS LYS GLY GLN n/a n/a
2 2IG0 - LYS ARG HIS ARG MLY VAL LEU ARG ASP ASN n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: SER SER HIS LEU MLY SER LYS LYS GLY GLN; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 SER SER HIS LEU MLY SER LYS LYS GLY GLN 1 1
2 THR SER ARG HIS LYS MLZ LEU MET PHE LYS 0.459459 0.852941
3 LYS ALA ALA ARG ALY SER ALA PRO ALA 0.404762 0.641026
Similar Ligands (3D)
Ligand no: 1; Ligand: SER SER HIS LEU MLY SER LYS LYS GLY GLN; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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