Receptor
PDB id Resolution Class Description Source Keywords
4B7E 2.5 Å EC: 1.14.11.30 FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH CONSENSUS ANKY DOMAIN-LEU PEPTIDE (20-MER) HOMO SAPIENS OXIDOREDUCTASE-PEPTIDE COMPLEX OXIDOREDUCTASE NON-HEME IROXOGLUTARATE DIOXYGENASE OXYGENASE DNA-BINDING METAL-BITRANSCRIPTION HELIX-LOOP-HELIX-BETA DSBH FACIAL TRIAD ASPARAGINYL/ ASPARTYL HYDROXYLASE TRANSCRIPTION AND EPIGENREGULATION SIGNALING ARD BETA-HYDROXYLATION TRANSCRIPTIACTIVATOR/INHIBITOR
Ref.: SUBSTRATE SELECTIVITY ANALYSES OF FACTOR INHIBITING HYPOXIA-INDUCIBLE FACTOR. ANGEW. CHEM. INT. ED. ENGL. V. 52 1700 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
OGA A:601;
Valid;
none;
submit data
147.086 C4 H5 N O5 C(C(=...
SO4 A:604;
A:602;
A:605;
A:606;
A:603;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
GOL A:608;
A:607;
A:609;
A:610;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
ZN A:501;
Part of Protein;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4B7E 2.5 Å EC: 1.14.11.30 FACTOR INHIBITING HIF-1 ALPHA IN COMPLEX WITH CONSENSUS ANKY DOMAIN-LEU PEPTIDE (20-MER) HOMO SAPIENS OXIDOREDUCTASE-PEPTIDE COMPLEX OXIDOREDUCTASE NON-HEME IROXOGLUTARATE DIOXYGENASE OXYGENASE DNA-BINDING METAL-BITRANSCRIPTION HELIX-LOOP-HELIX-BETA DSBH FACIAL TRIAD ASPARAGINYL/ ASPARTYL HYDROXYLASE TRANSCRIPTION AND EPIGENREGULATION SIGNALING ARD BETA-HYDROXYLATION TRANSCRIPTIACTIVATOR/INHIBITOR
Ref.: SUBSTRATE SELECTIVITY ANALYSES OF FACTOR INHIBITING HYPOXIA-INDUCIBLE FACTOR. ANGEW. CHEM. INT. ED. ENGL. V. 52 1700 2013
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4B7E - OGA C4 H5 N O5 C(C(=O)O)N....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 4B7E - OGA C4 H5 N O5 C(C(=O)O)N....
2 2Y0I - AKG C5 H6 O5 C(CC(=O)O)....
3 2XUM - OGA C4 H5 N O5 C(C(=O)O)N....
4 4B7K - OGA C4 H5 N O5 C(C(=O)O)N....
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3P3N - AKG C5 H6 O5 C(CC(=O)O)....
2 4B7E - OGA C4 H5 N O5 C(C(=O)O)N....
3 2Y0I - AKG C5 H6 O5 C(CC(=O)O)....
4 2XUM - OGA C4 H5 N O5 C(C(=O)O)N....
5 4B7K - OGA C4 H5 N O5 C(C(=O)O)N....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: OGA; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 OGA 1 1
2 AAC 0.461538 0.827586
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4B7E; Ligand: OGA; Similar sites found with APoc: 1
This union binding pocket(no: 1) in the query (biounit: 4b7e.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 6F4T OGA 46.2745
Pocket No.: 2; Query (leader) PDB : 4B7E; Ligand: OGA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4b7e.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
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