Receptor
PDB id Resolution Class Description Source Keywords
4CCN 2.23 Å EC: 1.14.11.27 60S RIBOSOMAL PROTEIN L8 HISTIDINE HYDROXYLASE (NO66 L299C/C COMPLEX WITH MN(II), N-OXALYLGLYCINE (NOG) AND 60S RIBOSOMAL 8 (RPL8 G220C) PEPTIDE FRAGMENT (COMPLEX-2) HOMO SAPIENS OXIDOREDUCTASE NON-HEME IRON-BINDING DSBH 2- OXOGLUTARATDIOXYGENASE JMJC DOMAIN RIBOSOME BIOGENESIS NUCLEAR PROTRPL8 BETA-HYDROXYLATION TRANSCRIPTION AND EPIGENETIC REGUSIGNALING
Ref.: RIBOSOMAL OXYGENASES ARE STRUCTURALLY CONSERVED FRO PROKARYOTES TO HUMANS. NATURE V. 510 422 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
OGA B:902;
A:902;
Valid;
Valid;
none;
none;
submit data
147.086 C4 H5 N O5 C(C(=...
EDO B:904;
Invalid;
none;
submit data
62.068 C2 H6 O2 C(CO)...
SO4 B:903;
A:903;
Invalid;
Invalid;
none;
none;
submit data
96.063 O4 S [O-]S...
MN B:901;
A:901;
Part of Protein;
Part of Protein;
none;
none;
submit data
54.938 Mn [Mn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4CCN 2.23 Å EC: 1.14.11.27 60S RIBOSOMAL PROTEIN L8 HISTIDINE HYDROXYLASE (NO66 L299C/C COMPLEX WITH MN(II), N-OXALYLGLYCINE (NOG) AND 60S RIBOSOMAL 8 (RPL8 G220C) PEPTIDE FRAGMENT (COMPLEX-2) HOMO SAPIENS OXIDOREDUCTASE NON-HEME IRON-BINDING DSBH 2- OXOGLUTARATDIOXYGENASE JMJC DOMAIN RIBOSOME BIOGENESIS NUCLEAR PROTRPL8 BETA-HYDROXYLATION TRANSCRIPTION AND EPIGENETIC REGUSIGNALING
Ref.: RIBOSOMAL OXYGENASES ARE STRUCTURALLY CONSERVED FRO PROKARYOTES TO HUMANS. NATURE V. 510 422 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 13 families.
1 4CCN - OGA C4 H5 N O5 C(C(=O)O)N....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 11 families.
1 4CCN - OGA C4 H5 N O5 C(C(=O)O)N....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 4CCO - OGA C4 H5 N O5 C(C(=O)O)N....
2 4CCN - OGA C4 H5 N O5 C(C(=O)O)N....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: OGA; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 OGA 1 1
2 AAC 0.461538 0.827586
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4CCN; Ligand: OGA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4ccn.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 4CCN; Ligand: OGA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4ccn.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 4CCN; Ligand: OGA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 4ccn.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 4CCN; Ligand: OGA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 4ccn.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
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