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Receptor
PDB id Resolution Class Description Source Keywords
4CS9 2.01 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE ASYMMETRIC HUMAN METAPNEUMOVIRUS M2-1 TETRAMER BOUND TO ADENOSINE MONOPHOSPHATE HUMAN METAPNEUMOVIRUS VIRAL PROTEIN ANTITERMINATOR TRANSCRIPTION ELONGATION RNA-BINDING MODULAR PROTEIN ASYMMETRIC TETRAMER
Ref.: DRASTIC CHANGES IN CONFORMATIONAL DYNAMICS OF THE ANTITERMINATOR M2-1 REGULATE TRANSCRIPTION EFFICIEN PNEUMOVIRINAE. ELIFE V. 3 02674 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
AMP A:1172;
B:1171;
C:1174;
C:1175;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
347.221 C10 H14 N5 O7 P c1nc(...
ZN E:1178;
C:1173;
A:1171;
B:1170;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4CS9 2.01 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE ASYMMETRIC HUMAN METAPNEUMOVIRUS M2-1 TETRAMER BOUND TO ADENOSINE MONOPHOSPHATE HUMAN METAPNEUMOVIRUS VIRAL PROTEIN ANTITERMINATOR TRANSCRIPTION ELONGATION RNA-BINDING MODULAR PROTEIN ASYMMETRIC TETRAMER
Ref.: DRASTIC CHANGES IN CONFORMATIONAL DYNAMICS OF THE ANTITERMINATOR M2-1 REGULATE TRANSCRIPTION EFFICIEN PNEUMOVIRINAE. ELIFE V. 3 02674 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 4CS9 - AMP C10 H14 N5 O7 P c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 4CS9 - AMP C10 H14 N5 O7 P c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 4CS9 - AMP C10 H14 N5 O7 P c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: AMP; Similar ligands found: 395
No: Ligand ECFP6 Tc MDL keys Tc
1 A 1 1
2 AMP 1 1
3 A2D 0.833333 0.943662
4 ABM 0.833333 0.943662
5 ADP 0.823529 0.971429
6 A12 0.808824 0.931507
7 AP2 0.808824 0.931507
8 BA3 0.808824 0.943662
9 SRA 0.80303 0.944444
10 AP5 0.797101 0.943662
11 B4P 0.797101 0.943662
12 HEJ 0.788732 0.971429
13 ATP 0.788732 0.971429
14 AT4 0.785714 0.931507
15 AN2 0.785714 0.957747
16 5FA 0.777778 0.971429
17 AQP 0.777778 0.971429
18 APC 0.777778 0.931507
19 CA0 0.774648 0.917808
20 M33 0.774648 0.930556
21 AU1 0.774648 0.944444
22 ADX 0.774648 0.848101
23 ACP 0.763889 0.944444
24 50T 0.763889 0.957747
25 25A 0.75641 0.971429
26 AR6 0.753425 0.943662
27 PRX 0.753425 0.917808
28 APR 0.753425 0.943662
29 ACQ 0.746667 0.944444
30 T99 0.746667 0.931507
31 TAT 0.746667 0.931507
32 SAP 0.743243 0.918919
33 AD9 0.743243 0.944444
34 AGS 0.743243 0.918919
35 RBY 0.743243 0.905405
36 ADV 0.743243 0.905405
37 ANP 0.723684 0.944444
38 ADP PO3 0.72 0.942857
39 6YZ 0.717949 0.944444
40 5AL 0.714286 0.930556
41 SON 0.712329 0.931507
42 LMS 0.710145 0.825
43 RAB 0.709677 0.842857
44 XYA 0.709677 0.842857
45 ADN 0.709677 0.842857
46 ATF 0.705128 0.931507
47 GAP 0.701299 0.891892
48 A22 0.7 0.957747
49 SRP 0.696203 0.905405
50 7D5 0.691176 0.902778
51 A3P 0.684932 0.971014
52 A2P 0.684932 0.956522
53 ADP ALF 0.683544 0.868421
54 ALF ADP 0.683544 0.868421
55 ADQ 0.682927 0.917808
56 MAP 0.679012 0.918919
57 ADP VO4 0.675 0.930556
58 VO4 ADP 0.675 0.930556
59 OOB 0.670732 0.930556
60 9ZA 0.670732 0.906667
61 8QN 0.670732 0.930556
62 5SV 0.670732 0.87013
63 9ZD 0.670732 0.906667
64 PTJ 0.670588 0.894737
65 AOC 0.666667 0.84507
66 PAJ 0.662651 0.858974
67 4AD 0.662651 0.893333
68 A3R 0.662651 0.881579
69 A1R 0.662651 0.881579
70 AMO 0.662651 0.905405
71 5N5 0.661538 0.816901
72 DAL AMP 0.658537 0.90411
73 IMO 0.657534 0.928571
74 AHX 0.654762 0.87013
75 00A 0.654762 0.881579
76 DLL 0.654762 0.930556
77 5AS 0.653333 0.776471
78 A4D 0.651515 0.816901
79 5CD 0.651515 0.828571
80 9X8 0.647059 0.893333
81 OAD 0.647059 0.917808
82 3UK 0.647059 0.917808
83 ADP BMA 0.647059 0.891892
84 25L 0.643678 0.957747
85 PR8 0.639535 0.848101
86 WAQ 0.639535 0.881579
87 LAD 0.639535 0.858974
88 B5V 0.639535 0.905405
89 DTA 0.637681 0.808219
90 V3L 0.6375 0.971429
91 3DH 0.633803 0.794521
92 BIS 0.632184 0.906667
93 ME8 0.632184 0.8375
94 3OD 0.632184 0.917808
95 FYA 0.632184 0.930556
96 NB8 0.632184 0.87013
97 1ZZ 0.632184 0.8375
98 TXA 0.632184 0.905405
99 MTA 0.628571 0.794521
100 3AM 0.625 0.956522
101 EP4 0.623188 0.773333
102 A A 0.62069 0.971429
103 9SN 0.617977 0.87013
104 M2T 0.614286 0.753247
105 JB6 0.613636 0.881579
106 YAP 0.611111 0.893333
107 B5Y 0.611111 0.893333
108 FA5 0.611111 0.905405
109 B5M 0.611111 0.893333
110 MYR AMP 0.606742 0.814815
111 G5A 0.604938 0.776471
112 XAH 0.604396 0.8375
113 4UV 0.597826 0.893333
114 71V 0.597403 0.906667
115 ATP A A A 0.593407 0.929577
116 PAP 0.592593 0.957143
117 G3A 0.591398 0.894737
118 2AM 0.589041 0.942857
119 5X8 0.5875 0.783784
120 6RE 0.586667 0.779221
121 6C6 0.585366 0.905405
122 AFH 0.585106 0.858974
123 4UU 0.585106 0.893333
124 G5P 0.585106 0.894737
125 GA7 0.585106 0.905405
126 7D3 0.584416 0.878378
127 A5A 0.583333 0.804878
128 TSB 0.581395 0.795181
129 AMP DBH 0.580645 0.891892
130 TYR AMP 0.580645 0.868421
131 2A5 0.580247 0.891892
132 DQV 0.578947 0.930556
133 DSH 0.578947 0.74359
134 GTA 0.578947 0.860759
135 TAD 0.578947 0.858974
136 6IA 0.578313 0.858974
137 SSA 0.576471 0.776471
138 AMZ 0.575342 0.888889
139 C2R 0.575342 0.876712
140 PGS 0.575 0.857143
141 7D4 0.575 0.878378
142 ZAS 0.573333 0.786667
143 ATR 0.573171 0.942857
144 LAQ 0.572917 0.8375
145 AAM 0.571429 1
146 J7C 0.571429 0.789474
147 A3N 0.571429 0.783784
148 PPS 0.571429 0.848101
149 AIR 0.571429 0.927536
150 52H 0.569767 0.776471
151 54H 0.569767 0.785714
152 VMS 0.569767 0.785714
153 AR6 AR6 0.568421 0.916667
154 ARG AMP 0.568421 0.82716
155 7MD 0.568421 0.8375
156 YLP 0.56701 0.817073
157 48N 0.56701 0.87013
158 OVE 0.565789 0.90411
159 UPA 0.565657 0.881579
160 2SA 0.564706 0.905405
161 S4M 0.564103 0.682353
162 5CA 0.563218 0.776471
163 53H 0.563218 0.776471
164 8X1 0.563218 0.75
165 UP5 0.561224 0.893333
166 NAI 0.561224 0.881579
167 6V0 0.561224 0.87013
168 NAX 0.561224 0.848101
169 4UW 0.561224 0.858974
170 DND 0.561224 0.905405
171 TXD 0.561224 0.881579
172 NXX 0.561224 0.905405
173 NIA 0.56 0.820513
174 D5M 0.558442 0.902778
175 DA 0.558442 0.902778
176 MAO 0.556962 0.777778
177 AHZ 0.556701 0.814815
178 OMR 0.555556 0.82716
179 ITT 0.555556 0.915493
180 TYM 0.555556 0.905405
181 TXE 0.555556 0.881579
182 5AD 0.552239 0.768116
183 A2R 0.551724 0.957747
184 LPA AMP 0.55102 0.814815
185 DSZ 0.550562 0.776471
186 NSS 0.550562 0.776471
187 LSS 0.550562 0.758621
188 AP0 0.55 0.87013
189 YLC 0.55 0.8375
190 4TC 0.55 0.87013
191 YLB 0.55 0.817073
192 P5A 0.549451 0.741573
193 139 0.54902 0.848101
194 A4P 0.544554 0.819277
195 NVA LMS 0.544444 0.75
196 GJV 0.544304 0.769231
197 7D7 0.544118 0.763889
198 9K8 0.543478 0.711111
199 A7D 0.54321 0.797297
200 AF3 ADP 3PG 0.54 0.835443
201 6K6 0.539326 0.957143
202 IOT 0.539216 0.829268
203 A3G 0.538462 0.797297
204 LEU LMS 0.538462 0.75
205 A5D 0.535714 0.808219
206 7MC 0.534653 0.817073
207 T5A 0.533981 0.817073
208 ADJ 0.533981 0.82716
209 YLA 0.533981 0.817073
210 GSU 0.532609 0.776471
211 KAA 0.532609 0.75
212 7RA 0.531646 0.985507
213 SFG 0.53012 0.77027
214 SAH 0.529412 0.763158
215 HFD 0.529412 0.918919
216 AYB 0.528846 0.807229
217 CNA 0.528846 0.905405
218 N6P 0.527473 0.942029
219 8BR 0.525 0.931507
220 F2R 0.52381 0.839506
221 80F 0.523364 0.817073
222 Y3J 0.521127 0.746479
223 YSA 0.520833 0.776471
224 7RP 0.518987 0.955882
225 BTX 0.518868 0.839506
226 NAD 0.518868 0.930556
227 COD 0.518868 0.788235
228 G A A A 0.518868 0.87013
229 MHZ 0.518072 0.714286
230 SA8 0.517647 0.725
231 6AD 0.517241 0.883117
232 DZD 0.514019 0.858974
233 BT5 0.514019 0.829268
234 RMB 0.5125 0.898551
235 SAI 0.511628 0.753247
236 AV2 0.511364 0.890411
237 8PZ 0.510417 0.776471
238 A3D 0.509259 0.917808
239 A3S 0.506024 0.808219
240 3AT 0.505747 0.943662
241 SAM 0.505747 0.707317
242 SMM 0.505618 0.702381
243 NA7 0.505376 0.931507
244 4TA 0.504673 0.804878
245 AMP NAD 0.504673 0.90411
246 EEM 0.5 0.707317
247 G 0.5 0.905405
248 NEC 0.5 0.743243
249 5GP 0.5 0.905405
250 AAT 0.5 0.725
251 YLY 0.495495 0.807229
252 M24 0.495495 0.848101
253 7C5 0.494949 0.815789
254 DAT 0.494118 0.878378
255 A3T 0.494118 0.819444
256 P2P 0.493827 0.928571
257 FAI 0.493827 0.888889
258 1RB 0.493671 0.911765
259 NAE 0.491071 0.893333
260 U A 0.490909 0.906667
261 NAJ PZO 0.490909 0.846154
262 A G 0.490741 0.881579
263 TM1 0.489583 0.771084
264 A A A 0.489362 0.90411
265 A6D 0.489362 0.740741
266 PO4 PO4 A A A A PO4 0.489362 0.901408
267 S7M 0.488889 0.707317
268 DTP 0.488636 0.878378
269 RBZ 0.4875 0.873239
270 101 0.4875 0.902778
271 EAD 0.486957 0.848101
272 NAQ 0.486726 0.87013
273 U A G G 0.486239 0.881579
274 4YB 0.485149 0.758621
275 NDE 0.483051 0.931507
276 ZID 0.482456 0.917808
277 N0B 0.482456 0.817073
278 WSA 0.480769 0.785714
279 RGT 0.479592 0.931507
280 ARU 0.478723 0.835443
281 GGZ 0.478261 0.8
282 JLN 0.47561 0.863014
283 ANZ 0.475248 0.820513
284 QQY 0.475 0.837838
285 ACK 0.475 0.885714
286 NAJ PYZ 0.473684 0.804878
287 S8M 0.473118 0.779221
288 GEK 0.473118 0.734177
289 AVV 0.473118 0.87013
290 3AD 0.472973 0.828571
291 A U 0.471698 0.868421
292 P1H 0.470588 0.82716
293 0UM 0.468085 0.716049
294 RVP 0.467532 0.847222
295 649 0.466667 0.741573
296 Z5A 0.465517 0.776471
297 PMO 0.464286 0.873239
298 SXZ 0.463918 0.707317
299 62X 0.463158 0.682353
300 QQX 0.4625 0.826667
301 8Q2 0.462264 0.75
302 2VA 0.45977 0.797297
303 IMP 0.458824 0.90411
304 K15 0.458333 0.698795
305 CC5 0.458333 0.84058
306 AS 0.457831 0.855263
307 DDS 0.455556 0.851351
308 V1N 0.455446 0.943662
309 NJP 0.454545 0.918919
310 7DD 0.453488 0.957143
311 93A 0.453488 0.804878
312 G7M 0.453488 0.87013
313 3L1 0.453333 0.77027
314 3D1 0.453333 0.77027
315 EO7 0.452381 0.785714
316 NDC 0.45082 0.87013
317 FB0 0.45082 0.781609
318 0WD 0.45045 0.894737
319 NVA 2AD 0.449438 0.75641
320 26A 0.447368 0.76
321 2FA 0.447368 0.810811
322 2BA 0.447059 0.914286
323 CMP 0.447059 0.927536
324 D3Y 0.446809 0.786667
325 KB1 0.444444 0.716049
326 APU 0.444444 0.893333
327 VRT 0.444444 0.766234
328 SO8 0.444444 0.786667
329 FDA 0.443548 0.809524
330 PUA 0.443478 0.858974
331 ODP 0.441441 0.883117
332 6FA 0.44 0.817073
333 103 0.439024 0.861111
334 RP1 0.439024 0.864865
335 SP1 0.439024 0.864865
336 3NZ 0.438776 0.779221
337 A C A C 0.438596 0.846154
338 7DT 0.438202 0.957143
339 NDP 0.436364 0.894737
340 NPW 0.436364 0.860759
341 MTP 0.434211 0.727273
342 FAS 0.433071 0.82716
343 SFD 0.433071 0.712766
344 FAD 0.433071 0.82716
345 IRN 0.432432 0.867647
346 ZZB 0.432432 0.792683
347 TXP 0.432432 0.894737
348 NZQ 0.432432 0.883117
349 62F 0.430769 0.8375
350 FNK 0.430769 0.781609
351 128 0.429907 0.752941
352 1DA 0.428571 0.842857
353 6MD 0.428571 0.805556
354 PAX 0.428571 0.82716
355 SLU 0.426087 0.767442
356 XNP 0.424779 0.848101
357 12D 0.424528 0.761905
358 5F1 0.423077 0.72973
359 ETB 0.422414 0.809524
360 DCA 0.422414 0.8
361 F0P 0.422018 0.725
362 WMP 0.421053 0.864865
363 GUO 0.421053 0.864865
364 FAY 0.416667 0.8375
365 38Y 0.415929 0.804878
366 5J9 0.415842 0.728395
367 COA 0.415254 0.8
368 0T1 0.415254 0.8
369 KH3 0.415094 0.690476
370 U A C C 0.413793 0.857143
371 N01 0.413793 0.90411
372 FMP 0.413793 0.871429
373 RFL 0.413534 0.797619
374 NMN AMP PO4 0.412281 0.868421
375 GP2 0.408602 0.858974
376 GDP 0.408602 0.893333
377 NAP 0.408333 0.944444
378 NOC 0.407895 0.760563
379 2ER 0.405941 0.831169
380 1PR 0.405941 0.820513
381 P5F 0.405797 0.8
382 CAO 0.404959 0.772727
383 TAP 0.404959 0.906667
384 30N 0.404959 0.731183
385 COS 0.404959 0.781609
386 AMX 0.404959 0.809524
387 XMP 0.402299 0.891892
388 G2P 0.402062 0.858974
389 APC G U 0.401709 0.833333
390 U A A U 0.401639 0.906667
391 CMX 0.401639 0.8
392 NA0 0.401639 0.931507
393 SCO 0.401639 0.8
394 9JJ 0.40146 0.8375
395 F2N 0.4 0.790698
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4CS9; Ligand: AMP; Similar sites found with APoc: 402
This union binding pocket(no: 1) in the query (biounit: 4cs9.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 5H5O PCG None
2 1JYQ MAZ PTR PTM ASN None
3 2Z3H BLO None
4 4G7A AZM None
5 5K8S CMP None
6 4OOP DUP None
7 2D7C GTP None
8 3TLJ SAH 1.0582
9 3R35 4CO 1.3245
10 4H2D FMN 1.81818
11 3P48 DUP 2.04082
12 1SQL GUN 2.05479
13 4QIJ 1HA 2.1164
14 1CDO NAD 2.1164
15 3HY3 10F 2.1164
16 2XOC ADP 2.1164
17 3EKK GS2 2.1164
18 5TA6 79D 2.1164
19 4OH4 ANP 2.1164
20 6H36 FKE 2.1164
21 5BSZ SAH 2.1164
22 4JWJ SAH 2.1164
23 1JXN MFU 2.1164
24 2XOC ADE 2.1164
25 3FC2 IBI 2.1164
26 2R7K AMZ 2.1164
27 2R7K ACP 2.1164
28 5J60 FAD 2.1164
29 6BSX E7S 2.24719
30 6BSX GDP 2.24719
31 4C5N ACP 2.6455
32 4ZDC CO8 2.6455
33 4C5N PXL 2.6455
34 2NP9 YE1 2.6455
35 5W4W 9WG 2.6455
36 5OKT 9XK 2.6455
37 4N9I PCG 2.6455
38 5X8I SQZ 2.6455
39 1PL6 572 2.6455
40 6FYV 3NG 2.6455
41 6G33 5ID 2.6455
42 2VSS ACO 2.6455
43 3M2W L8I 2.6455
44 1PL6 NAD 2.6455
45 1GSA ADP 2.6455
46 5E2N V14 2.6455
47 5JLB SAH 2.6455
48 5EOB 5QQ 2.6455
49 2QTR NXX 2.6455
50 4KBA 1QM 2.6455
51 3ALN ANP 2.6455
52 3TWO NDP 2.6455
53 2PHN GDP 2.6455
54 2R4J FAD 2.6455
55 2R4J 13P 2.6455
56 5WP4 SAH 2.6455
57 5UIU 8CG 2.6455
58 3OKP GDD 2.6455
59 4FMU 0UM 2.6455
60 5TUZ 7L6 2.6455
61 5TUZ SAM 2.6455
62 3FVQ ATP 2.6455
63 1S4M LUM 2.6455
64 5GSN MMZ 2.86976
65 5GSN FAD 2.86976
66 5GSN NAP 2.86976
67 5WA9 9ZD 3.10078
68 3UDZ ADP 3.1746
69 5UCD NAP 3.1746
70 2WU6 DKI 3.1746
71 4LOO SB4 3.1746
72 1M0W ANP 3.1746
73 5HW4 SAM 3.1746
74 4AP3 FAD 3.1746
75 4AP3 NAP 3.1746
76 3DAK ANP 3.1746
77 1A8R GTP 3.1746
78 5BUK FAD 3.1746
79 1AV5 AP2 3.1746
80 6FYL 3NG 3.1746
81 3LCC SAH 3.1746
82 3WO0 ADP 3.1746
83 3WO0 ALA 3.1746
84 5TXR PLP 3.1746
85 4PNE SAH 3.1746
86 4YGF AZM 3.1746
87 2IO8 ADP 3.1746
88 2WE0 UMP 3.1746
89 5GM1 SAH 3.1746
90 6AC9 ANP 3.1746
91 4JGP PYR 3.1746
92 1MXH NAP 3.1746
93 1MXH DHF 3.1746
94 1LCK GLU GLY GLN PTR GLN PRO GLN PRO ALA 3.42857
95 5RHN 8BR 3.47826
96 6FL8 ADP 3.61702
97 6FL8 TIY 3.61702
98 2XVE FAD 3.66379
99 2XVF FAD 3.66379
100 1ON3 MCA 3.7037
101 5BV3 M7G 3.7037
102 6CGD GNP 3.7037
103 6CGD AKN 3.7037
104 1TZD ADP 3.7037
105 1IA9 ANP 3.7037
106 5KOX RFP 3.7037
107 5KOX FAD 3.7037
108 3C1X CKK 3.7037
109 3I59 N6S 3.7037
110 6HOY TSN 3.7037
111 6HOY AR6 3.7037
112 1L8B MGP 3.7037
113 1GJC 130 3.7037
114 2JL1 NAP 3.7037
115 4OM8 NAD 3.7037
116 5V22 SAH 3.7037
117 1H9A NAP 3.7037
118 3PP0 03Q 3.7037
119 5MJA 7O3 3.7037
120 4YZN 4K5 3.7037
121 1X87 NAD 3.7037
122 3ZG6 APR 3.7037
123 2VQD AP2 3.7037
124 3TXO 07U 3.7037
125 4COQ SAN 3.7037
126 2V58 LZJ 3.7037
127 4J4H NAI 3.7037
128 4J4H 1J1 3.7037
129 2AMT 1AA 3.77358
130 5F90 LMR 3.84615
131 5F90 GLA GAL 3.84615
132 5F90 GLA GAL BGC 5VQ 3.84615
133 3OZV FAD 3.97022
134 2A19 ANP 4
135 1VLH PNS 4.04624
136 4Z4P SAH 4.21687
137 3FHR P4O 4.2328
138 4DQL NAP 4.2328
139 4DQL FAD 4.2328
140 1Q8Y ADP 4.2328
141 1Q8Y ADE 4.2328
142 2FR1 NDP 4.2328
143 1VEM GLC GLC 4.2328
144 4UXL 5P8 4.2328
145 2QA1 FAD 4.2328
146 4WHZ 3NL 4.2328
147 4CLI 5P8 4.2328
148 5AWM ANP 4.2328
149 3UA1 08Y 4.2328
150 3C8Z 5CA 4.2328
151 3E7O 35F 4.2328
152 4LWA Q13 4.2328
153 3IGO ANP 4.2328
154 1R37 NAD 4.2328
155 6A5K SAM 4.2328
156 6D6Y SAH 4.2328
157 4GKV NAD 4.2328
158 2AQX ATP 4.2328
159 3OKA GDD 4.2328
160 3KLL MAL 4.2328
161 3VSV XYS 4.2328
162 1S7G APR 4.2328
163 6F97 FAD 4.2328
164 5JKG 6LF 4.7619
165 2C29 DQH 4.7619
166 1PFY MSP 4.7619
167 2XK9 XK9 4.7619
168 2YJP CYS 4.7619
169 2GQS ADP 4.7619
170 2IID FAD 4.7619
171 2IID PHE 4.7619
172 1T36 ADP 4.7619
173 5CJF 520 4.7619
174 5GXU FMN 4.7619
175 2GQR ADP 4.7619
176 2VPQ ANP 4.7619
177 3FRH SAH 4.7619
178 3BK2 U5P 4.7619
179 5DEY 59T 4.7619
180 5GXU FAD 4.7619
181 4WUP 3UF 4.7619
182 5ETR APC 4.96894
183 5ETR 5RW 4.96894
184 2A0S BIO 5
185 1NU4 MLA 5.15464
186 2IF8 ADP 5.29101
187 4IZC 1GZ 5.29101
188 3UIM ANP 5.29101
189 3I0O ADP 5.29101
190 4BTV RB3 5.29101
191 5YJF SAH 5.29101
192 5JBX COA 5.29101
193 1DUB CAA 5.29101
194 4NJH 2K8 5.29101
195 4IZY 1J2 5.29101
196 4NJH SAM 5.29101
197 4X3R 686 5.29101
198 4OCV ANP 5.29101
199 1YQD NAP 5.29101
200 1DMY AZM 5.29101
201 4JSR 1NQ 5.29101
202 4UX9 ANP 5.29101
203 3ICS FAD 5.29101
204 3ICR FAD 5.29101
205 5YJF 8WO 5.29101
206 1NV8 SAM 5.29101
207 1NV8 MEQ 5.29101
208 5Z2L NDP 5.29101
209 5UKL SIX 5.29101
210 2IVD FAD 5.29101
211 4YNM SAM 5.29101
212 4USF 6UI 5.29101
213 5AVF TAU 5.29101
214 5MPT SAH 5.29101
215 4CRL C1I 5.29101
216 3OU2 SAH 5.29101
217 5MLJ 9ST 5.35714
218 3A6T 8OG 5.42636
219 3KMW ATP 5.42636
220 2Q37 3AL 5.52486
221 1ZEI CRS 5.66038
222 4C3Y ANB 5.82011
223 4C3Y FAD 5.82011
224 3DLG GWE 5.82011
225 5VCV 1N1 5.82011
226 3KN5 ANP 5.82011
227 8CAT NDP 5.82011
228 1H82 GZZ 5.82011
229 1H82 FAD 5.82011
230 6FE1 V14 5.82011
231 3RFA SAM 5.82011
232 4WW8 VD9 5.82011
233 4OCJ NDG 5.82011
234 2YAB AMP 5.82011
235 4X5S AZM 5.82011
236 5OVK NDP 5.82011
237 4EN4 GT0 5.82011
238 4EN4 GT1 5.82011
239 4EN4 ATP 5.82011
240 3UR0 SVR 5.82011
241 4K4D HFQ 5.83942
242 3PNA CMP 5.84416
243 5XLY C2E 6.01504
244 1M26 GAL A2G 6.01504
245 1TMM APC 6.32911
246 1TMM HHR 6.32911
247 3EBL GA4 6.34921
248 4B7H NDP 6.34921
249 4ZS4 ATP 6.34921
250 3FSY SCA 6.34921
251 1FWM CB3 6.34921
252 4RQU NAD 6.34921
253 2BMB PMM 6.34921
254 1LLU NAD 6.34921
255 5UQW GDP 6.34921
256 4YRY NAD 6.34921
257 3O26 NDP 6.34921
258 3MB5 SAM 6.34921
259 5C1P ADP 6.34921
260 5IGL BMF 6.45161
261 4K49 HFQ 6.61765
262 4FGC PQ0 6.66667
263 2Q4H AMP 6.87831
264 1EFV FAD 6.87831
265 1EFV AMP 6.87831
266 4E93 GUI 6.87831
267 2OHH FMN 6.87831
268 5OGX FAD 6.87831
269 1T8U UAP SGN IDS SGN 6.87831
270 1E5Q NDP 6.87831
271 2G86 UMP 6.87831
272 4AX9 N5N 6.87831
273 1U7Z PMT 6.87831
274 3QO8 SSA 6.87831
275 5EKO N17 6.87831
276 4CQM NAP 6.87831
277 3X01 AMP 7.12468
278 1O97 AMP 7.40741
279 1O97 FAD 7.40741
280 4O4F ATP 7.40741
281 4O4F IHP 7.40741
282 1PHK ATP 7.40741
283 1I1N SAH 7.40741
284 2CSN CKI 7.40741
285 5MZI FAD 7.40741
286 5MZI FYK 7.40741
287 1CX4 CMP 7.40741
288 5OES ADP 7.40741
289 5JJR SAH 7.40741
290 4H3P ANP 7.40741
291 4H3Q ANP 7.40741
292 5FDZ 5X0 7.56302
293 1NBU PH2 7.56302
294 4INI AMP 7.69231
295 5LJ0 6XX 7.69231
296 2VSU ACO 7.93651
297 2JHF NAD 7.93651
298 5H2U 1N1 7.93651
299 1MO9 KPC 7.93651
300 1MO9 FAD 7.93651
301 3BZ3 YAM 7.93651
302 4OXI GAP 7.93651
303 4U03 TLL 7.93651
304 4U03 GTP 7.93651
305 5ML0 P2L 8.18182
306 4WOP CTP 8.44444
307 5MW8 ATP 8.46561
308 1U3U BNF 8.46561
309 1U3U NAD 8.46561
310 3PLS ANP 8.46561
311 5FI3 NAP 8.46561
312 6A1G 9OL 8.46561
313 2C31 ADP 8.46561
314 1D1T NAD 8.46561
315 2C31 TZD 8.46561
316 4NZN ANP 8.46561
317 4NZN 2OU 8.46561
318 1BC5 SAH 8.46561
319 4K38 SAM 8.46561
320 5W7M SAH 8.46561
321 5JGL SAM 8.46561
322 5ABU GTG 8.57143
323 4I42 1HA 9.52381
324 5MY8 RXZ 9.52381
325 1HK8 DGT 9.52381
326 3QWI CUE 9.52381
327 5HTL C2E 9.65517
328 4I4Z 2NE 10.0529
329 1W2D 4IP 10.0529
330 1W2D ADP 10.0529
331 4IOK ADP 10.0529
332 3GMB FAD 10.0529
333 4A4X JUP 10.0529
334 4IOK XPO 10.0529
335 4PTN PYR 10.0529
336 3WLE NAD 10.5572
337 2ZV2 609 10.582
338 4BMO FMN 10.582
339 5FAL COA 10.582
340 5FAL SKT 10.582
341 3RUV ANP 10.582
342 3AKK ADP 10.582
343 4XYM A12 10.582
344 5T8O 76Z 10.582
345 5O1I 9GH 11.1111
346 4IDT T28 11.1111
347 5BRT FAD 11.1111
348 5BRT CH9 11.1111
349 3GC8 B45 11.1111
350 5VC5 96M 11.1111
351 1HE1 AF3 11.3636
352 5DY5 5GR 11.6402
353 5HXI FAD 11.6402
354 3WDM ADN 11.6402
355 5ZAI COA 11.6402
356 3S5W FAD 11.6402
357 4ELG 52J 12.0482
358 4OUC 5ID 12.1693
359 5WS9 AMP 12.6984
360 4B63 ORN 12.6984
361 4B63 NAP 12.6984
362 4B63 FAD 12.6984
363 3DLS ADP 12.6984
364 6DF7 G9V 13.1737
365 4GYI ADP 13.2275
366 5I35 ANP 13.7566
367 3QF7 ANP 14
368 1CM8 ANP 14.2857
369 5YJI 8WO 14.2857
370 5YJI SAH 14.2857
371 3LXD FAD 14.2857
372 1O44 852 14.8148
373 5NMX NAP 14.8148
374 5NMX FAD 14.8148
375 4NFE BEN 14.8148
376 5EYK 5U5 15.2542
377 1WUR 8DG 15.3439
378 1ST0 GTG 15.873
379 2DM6 NAP 15.873
380 2DM6 IMN 15.873
381 3GNI ATP 15.873
382 5MG2 7M8 16.0584
383 5TDF ADP 16.4021
384 1EZ0 NAP 17.4603
385 1HFE CYS 17.9894
386 1GP6 DH2 17.9894
387 1GP6 SIN 17.9894
388 1GP6 QUE 17.9894
389 1YQZ FAD 17.9894
390 5Y86 HRM 17.9894
391 4COL DTP 18.5185
392 2V7O DRN 18.5185
393 4FF8 14S 18.5185
394 3RWP ABQ 19.0476
395 3FGC FMN 19.0476
396 2Q2Y ADP 21.164
397 2Q2Y MKR 21.164
398 4M69 ANP 21.4058
399 5IM3 DTP 21.6931
400 5U6C 7YS 24.8677
401 1SG4 CO8 31.746
402 2R3A SAM 33.3333
Pocket No.: 2; Query (leader) PDB : 4CS9; Ligand: AMP; Similar sites found with APoc: 84
This union binding pocket(no: 2) in the query (biounit: 4cs9.bio1) has 5 residues
No: Leader PDB Ligand Sequence Similarity
1 5LDQ NAP None
2 4YBN FAD None
3 1MR3 G3D None
4 2VZ6 FEF None
5 2F57 23D 2.1164
6 2WEL K88 2.1164
7 5XVG 8FX 2.1164
8 2GCE RFC 2.1164
9 2GCE SFC 2.1164
10 3HNA SAH 2.6455
11 3SWC SAH 2.6455
12 2RFI SAH 2.6455
13 2AAW GTX 2.6455
14 6G14 G4P 2.6455
15 5UPK ANP 2.7027
16 1Q7E MET 3.1746
17 2JLD AG1 3.1746
18 5ZZ6 NAD 3.1746
19 3MQG UDP 3.1746
20 4Y93 746 3.1746
21 1VGR COA 3.1746
22 3MQG U5P 3.1746
23 3MQG ACO 3.1746
24 3NW7 LGV 3.7037
25 2B4Q NAP 3.7037
26 2WGH DTP 3.7037
27 1Z3C SA8 3.7037
28 1PUJ GNP 3.7037
29 3JQ9 NAP 4.2328
30 3BMN NAP 4.2328
31 4CM4 NAP 4.2328
32 4CLR NAP 4.2328
33 4CM8 NAP 4.2328
34 3BMO NAP 4.2328
35 3JQA NAP 4.2328
36 5K6A NAP 4.2328
37 3JQ7 NAP 4.2328
38 2WD7 NAP 4.2328
39 4CMI NAP 4.2328
40 5JDI NAP 4.2328
41 5JCJ NAP 4.2328
42 3JQ8 NAP 4.2328
43 3BMQ NAP 4.2328
44 3JQF NAP 4.2328
45 2WJG GDP 4.25532
46 2PUL ACP 4.7619
47 1FQJ GDP 4.7619
48 2A5F GTP 5.14286
49 1NZY BCA 5.29101
50 1JXZ BCA 5.29101
51 5T0K SAM 5.29101
52 4EUU BX7 5.29101
53 4NVQ SAH 5.29101
54 4NVQ 2OD 5.29101
55 5JIY SAM 5.29101
56 1S9D GDP 5.4878
57 6AU6 GDP 5.82011
58 3OIG NAD 5.82011
59 5XKT GNP 6.34921
60 1NVV GNP 6.62651
61 3KUD GDP 6.62651
62 1GOT GDP 6.84932
63 4KS7 X4Z 6.87831
64 1I9G SAM 6.87831
65 2HY0 306 6.87831
66 1W55 C 7.93651
67 3UBM COA 7.93651
68 4QTB 38Z 7.93651
69 5UR1 YY9 8.46561
70 3TYZ PAB 8.46561
71 3TYZ XHP 8.46561
72 4HI0 GDP 8.99471
73 1MID LAP 9.89011
74 5KZD RCJ 10.582
75 1JQ9 PHE LEU SER TYR LYS 10.7438
76 2VJM COA 10.9813
77 3M1I GTP 11.1111
78 1FK8 NAD 11.1111
79 1WA5 GTP 12.6984
80 4K81 GTP 14.2857
81 5O74 GDP 17.2222
82 4C2W ANP 19.2308
83 3E5A VX6 20.4545
84 4C2V YJA 22.7273
Pocket No.: 3; Query (leader) PDB : 4CS9; Ligand: AMP; Similar sites found with APoc: 42
This union binding pocket(no: 3) in the query (biounit: 4cs9.bio1) has 6 residues
No: Leader PDB Ligand Sequence Similarity
1 5O42 NAD None
2 5O42 BGC None
3 5O42 9JW None
4 1UZN NAP 1.5873
5 5T9F TYR 2.1164
6 5T9F NAP 2.1164
7 3LA3 2FT 2.6455
8 4AG8 AXI 3.1746
9 5USZ SKE 3.1746
10 5OVL NAP 3.1746
11 1PN0 FAD 3.1746
12 1PN0 IPH 3.1746
13 1YKJ FAD 3.1746
14 1YKJ PHB 3.1746
15 2NYA MGD 3.1746
16 3I59 N6R 3.7037
17 3LCV SAM 4.2328
18 2XHK AKG 4.2328
19 2XKO AKG 4.2328
20 3X1M COA 4.40252
21 5HJM MTA 4.7619
22 2RGO FAD 5.29101
23 2CWH PYC 5.29101
24 2CWH NDP 5.29101
25 5EPO NAP 5.29101
26 3COW 52H 5.82011
27 1ATL 0QI 5.82011
28 3CEV ARG 5.82011
29 4D42 NAP 5.82011
30 4D42 W0I 5.82011
31 4ZOW CLM 5.82011
32 4F9C 0SX 6.34921
33 1XDY MTE 7.40741
34 4X9M FAD 7.40741
35 5Z2F NAP 7.40741
36 3C1M ANP 8.46561
37 2Q7V FAD 8.99471
38 4TWP AXI 8.99471
39 4XYB NDP 10.0529
40 3FW3 ETS 11.1111
41 5DNC ASN 13.2275
42 1FFU FAD 14.8148
Pocket No.: 4; Query (leader) PDB : 4CS9; Ligand: AMP; Similar sites found with APoc: 252
This union binding pocket(no: 4) in the query (biounit: 4cs9.bio1) has 9 residues
No: Leader PDB Ligand Sequence Similarity
1 2VN9 GVD None
2 2V1O COA None
3 2EWM NAD None
4 3BGD SAH None
5 3BGD PM6 None
6 5FA8 SAM None
7 3G89 SAM None
8 4OBW SAM None
9 2BZG SAH None
10 4WNP 3RJ None
11 4WB6 ATP 1.5873
12 1I8T FAD 1.5873
13 2PYW ADP 2.1164
14 1FP1 SAH 2.1164
15 1EHI ADP 2.1164
16 2ZIF SAM 2.1164
17 1LSS NAD 2.14286
18 4LRJ ANP 2.36686
19 5WP5 SAH 2.6455
20 6ECU SAH 2.6455
21 6ECW SAH 2.6455
22 4G17 0VN 2.6455
23 3KRL KRL 2.6455
24 2VDV SAM 2.6455
25 4IEN COA 3.06748
26 2PZI AXX 3.1746
27 3VPB ADP 3.1746
28 5YK1 ANP 3.1746
29 2QK4 ATP 3.1746
30 3VPC ADP 3.1746
31 4NFN 2KC 3.1746
32 4IWN GEK 3.1746
33 6EPY RAF 3.1746
34 4BTK DTQ 3.1746
35 2I7N ACO 3.1746
36 3VOT ADP 3.1746
37 4ASE AV9 3.1746
38 3F7Z 34O 3.1746
39 4NM5 ADP 3.1746
40 6GKV SAH 3.1746
41 3ZRM ZRM 3.1746
42 3GGF GVD 3.1746
43 1H74 ADP 3.37838
44 1H74 ILE 3.37838
45 6GR0 F8W 3.44828
46 3A4T SFG 3.7037
47 4Y0X ADP 3.7037
48 3P9C SAH 3.7037
49 2EG5 SAH 3.7037
50 1N2X SAM 3.7037
51 2I7C AAT 3.7037
52 2EFJ SAH 3.7037
53 3SXS PP2 3.7037
54 6BXI ANP 3.7037
55 2PT9 S4M 3.7037
56 2PT9 2MH 3.7037
57 3HDY GDU 3.7037
58 3HDY FDA 3.7037
59 3HDY FAD 3.7037
60 4U0I 0LI 3.7037
61 4RIF 3R2 3.7037
62 1O9U ADZ 3.7037
63 6CQF F97 3.7037
64 1XDS SAM 4.2328
65 1QZZ SAM 4.2328
66 5Y1G AKB 4.2328
67 5Y1G NAD 4.2328
68 1ZGA SAH 4.2328
69 2YW2 ATP 4.2328
70 5ERG SAM 4.2328
71 4M73 SAH 4.2328
72 3PTG 932 4.2328
73 5FA5 MTA 4.2328
74 4GQB 0XU 4.2328
75 3A4V PYR 4.2328
76 3A4V NAD 4.2328
77 4M73 M72 4.2328
78 4X60 SFG 4.2328
79 4X60 3XV 4.2328
80 4KIB SAH 4.2328
81 4CSV STI 4.2328
82 2XVD AS6 4.2328
83 2QE0 NAP 4.2328
84 2Z7R STU 4.2328
85 5TO8 7FM 4.2328
86 4BCN T9N 4.2328
87 2WPB ZZI 4.2328
88 1UAY ADN 4.2328
89 1Z83 AP5 4.2328
90 5FJN BE2 4.2328
91 5FJN FAD 4.2328
92 2J7T 274 4.2328
93 6FHO FAD 4.2328
94 5VZ0 ADP 4.2328
95 3LKZ SFG 4.7619
96 6ECT SAM 4.7619
97 6C8R EQV 4.7619
98 6C8R SAH 4.7619
99 2QCS ANP 4.7619
100 5VN0 FAD 4.7619
101 1JQ3 AAT 4.7619
102 1DL5 SAH 4.7619
103 1V59 NAD 4.7619
104 4G31 0WH 4.7619
105 4WB7 ATP 4.7619
106 4DC2 ADE 4.7619
107 3GEG NAD 4.7619
108 2WQN ADP 4.7619
109 5DXT 5H5 4.7619
110 4OAV ACP 4.7619
111 4YMH SAH 4.7619
112 1P1C SAH 4.7619
113 5TT6 ATP 4.7619
114 4WNK 453 4.7619
115 3ETH ATP 4.78873
116 1Q0S SAH 5.01931
117 4QTU SAM 5.18518
118 1U59 STU 5.29101
119 5K7U SAM 5.29101
120 4QMN DB8 5.29101
121 3EVG SAH 5.29101
122 3B4Y F42 5.29101
123 4TSK NDP 5.29101
124 5ZIC BMA Z4Y NAG 5.29101
125 6GIN IR2 5.29101
126 6EL3 NAP 5.29101
127 5DH3 5BS 5.29101
128 4PU5 ANP 5.29101
129 4FL3 ANP 5.35433
130 1OBD ATP 5.82011
131 4U44 3D9 5.82011
132 3QOX SAH 5.82011
133 5A6N U7E 5.82011
134 1Y8Q ATP 5.82011
135 3G5D 1N1 5.82011
136 5MW4 5JU 5.82011
137 4FZV SAM 5.82011
138 3W0O ADP 5.82011
139 3W0O HY0 5.82011
140 5M06 ADP 5.82011
141 4ZFL 4NK 5.82011
142 3FHI ANP 5.84416
143 4RPL 3UC 6.34921
144 4RPL FAD 6.34921
145 4Y8D 49J 6.34921
146 5C1P DAL DAL 6.34921
147 3TPV ADE 6.34921
148 4L6C 0BT 6.34921
149 4YRY FAD 6.34921
150 5ODT ADP 6.34921
151 4GJ3 0XP 6.34921
152 2F2U M77 6.34921
153 2CDU FAD 6.34921
154 3Q60 ATP 6.34921
155 4JR7 GNP 6.41711
156 1EJ0 SAM 6.66667
157 5ULP KB1 6.87831
158 3I53 SAH 6.87831
159 1IM8 SAI 6.87831
160 1XHL NDP 6.87831
161 3VP6 HLD 6.87831
162 1UNQ 4IP 7.2
163 4A6D SAM 7.40741
164 5N9T 8QQ 7.40741
165 4CQE CQE 7.40741
166 5ICE SAH 7.40741
167 6FDF SAH 7.40741
168 4XV1 904 7.40741
169 5DX0 SFG 7.40741
170 5DX8 SFG 7.40741
171 2BME GNP 7.52688
172 3ELW SAM 7.93651
173 3ELW GP3 7.93651
174 5EEH SAH 7.93651
175 5EEH P9P 7.93651
176 6C5B SAH 7.93651
177 1VJY 460 7.93651
178 6CZ3 FLJ 7.93651
179 4YSX FAD 7.97872
180 1Z2P I3S 8.46561
181 1Z2P ACP 8.46561
182 4ONA UW1 8.46561
183 1KJ8 GAR 8.46561
184 1KJ8 ATP 8.46561
185 5JZJ AN2 8.46561
186 1XKQ NDP 8.46561
187 3IDB ANP 8.69565
188 4PNI KQQ 8.99471
189 2Y6O 1N1 8.99471
190 4BHN BH9 8.99471
191 1N62 MCN 8.99471
192 1G55 SAH 9.52381
193 4EWH T77 9.52381
194 5EQY 5RA 9.52381
195 2R5T ANP 9.52381
196 1GY8 NAD 9.52381
197 3E1T FAD 9.52381
198 5BW4 SAM 9.52381
199 1FP2 SAH 10.0529
200 3MVH WFE 10.0529
201 4I94 ANP 10.0529
202 5EH0 5NW 10.0529
203 2PX8 SAH 10.4089
204 3TKY SAH 10.582
205 5BVA FAD 10.582
206 5KOK SAH 11.1111
207 4ZRN NAD 11.1111
208 4ZRN UPG 11.1111
209 1E4E ADP 11.1111
210 5KOK S9T 11.1111
211 5KOK R9T 11.1111
212 5J5R 6G1 11.1111
213 5J5R IMP 11.1111
214 4OTH DRN 11.1111
215 4Q0A GLY HIS LYS ILE LEU HIS ARG LEU LEU GLN 11.1111
216 4E70 N7I 11.6402
217 5HES 032 11.6402
218 3LST SAH 11.6402
219 5IBE 69M 11.6402
220 6G34 5ID 12.1693
221 1NML CIT 12.6984
222 5OA6 9PT 12.6984
223 1IHU AF3 12.6984
224 1IHU ADP 12.6984
225 5CUQ NSC 13.2275
226 4EUE NAI 13.2275
227 3GDH SAH 13.2275
228 2B9F ADP 13.2275
229 3EGI ADP 13.2275
230 3KV8 FAH 13.6691
231 1KYZ SAH 14.2857
232 2UUU FAD 14.8148
233 2UUU PL3 14.8148
234 3V8S 0HD 14.8148
235 3GCZ SAM 15.3439
236 3EVF SAH 15.3439
237 3EVF GTA 15.3439
238 3V4S ATP 15.3439
239 3V4S ADP 15.3439
240 3P2E SAH 15.3439
241 1BYG STU 15.3439
242 2DJH 3PD UM3 15.6522
243 3SRV S19 15.873
244 5GZ9 ANP 15.873
245 4F4P 0SB 15.873
246 4FG8 ATP 16.9312
247 5WLB GNP 17.6471
248 5LVP ATP 19.0476
249 5DF1 58X 19.0476
250 5DF1 NAP 19.0476
251 1FHX 4IP 19.3798
252 2P41 SAH 22.7513
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