Receptor
PDB id Resolution Class Description Source Keywords
4D4I 2 Å NON-ENZYME: OTHER UNDERSTANDING BI-SPECIFICITY OF A-DOMAINS PLANKTOTHRIX AGARDHII HYDROLASE NON-RIBOSOMAL PEPTIDE SYNTHETASE ADENYLATION A
Ref.: STRUCTURAL ELUCIDATION OF THE BISPECIFICITY OF A DO A BASIS FOR ACTIVATING NON-NATURAL AMINO ACIDS. ANGEW.CHEM.INT.ED.ENGL. V. 54 8833 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ANP A:1490;
 Valid;
 Atoms found MORE than expected: % Diff = 2;
 submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
MG A:1493;
 Part of Protein;
 none;
 submit data
24.305 Mg [Mg+2...
GOL A:1492;
 Invalid;
 none;
 submit data
92.094 C3 H8 O3 C(C(C...
ARG A:1491;
 Valid;
 none;
 submit data
175.209 C6 H15 N4 O2 C(C[C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4D57 2 Å NON-ENZYME: OTHER UNDERSTANDING BI-SPECIFICITY OF A-DOMAINS PLANKTOTHRIX AGARDHII TRANSCRIPTION NON-RIBOSOMAL PEPTIDE SYNTHETASE ADENYLATIONDOMAIN
Ref.: STRUCTURAL ELUCIDATION OF THE BISPECIFICITY OF A DO A BASIS FOR ACTIVATING NON-NATURAL AMINO ACIDS. ANGEW.CHEM.INT.ED.ENGL. V. 54 8833 2015
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1610 families.
1 4D4G - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 4D56 - TYR AMP n/a n/a
3 4D57 - ARG AMP n/a n/a
4 4D4I - ARG C6 H15 N4 O2 C(C[C@@H](....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1331 families.
1 4D4G - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 4D56 - TYR AMP n/a n/a
3 4D57 - ARG AMP n/a n/a
4 4D4I - ARG C6 H15 N4 O2 C(C[C@@H](....
50% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1144 families.
1 4D4G - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 4D56 - TYR AMP n/a n/a
3 4D57 - ARG AMP n/a n/a
4 4D4I - ARG C6 H15 N4 O2 C(C[C@@H](....
5 1AMU - AMP C10 H14 N5 O7 P c1nc(c2c(n....
6 5N81 - 8Q2 C22 H25 N7 O8 S C#CCOc1ccc....
7 5N82 - 8PZ C19 H23 N7 O7 S c1ccc(cc1)....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: ANP; Similar ligands found: 429
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 ADP 0.802632 0.972222
4 AP5 0.802632 0.945205
5 B4P 0.802632 0.945205
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 ATP 0.772152 0.972222
9 HEJ 0.772152 0.972222
10 AN2 0.769231 0.986111
11 AT4 0.769231 0.933333
12 AQP 0.7625 0.972222
13 5FA 0.7625 0.972222
14 M33 0.759494 0.932432
15 MAP 0.752941 0.972973
16 ACP 0.75 0.945946
17 APR 0.740741 0.945205
18 AR6 0.740741 0.945205
19 ACQ 0.73494 0.945946
20 AD9 0.731707 0.945946
21 AGS 0.731707 0.921053
22 KG4 0.728395 0.92
23 AMP 0.723684 0.944444
24 A 0.723684 0.944444
25 ATF 0.717647 0.933333
26 CA0 0.716049 0.92
27 ADX 0.716049 0.851852
28 6YZ 0.709302 0.945946
29 50T 0.707317 0.932432
30 PRX 0.698795 0.87013
31 ABM 0.696203 0.893333
32 45A 0.696203 0.893333
33 AMP MG 0.692308 0.90411
34 HQG 0.681818 0.958904
35 A12 0.679012 0.933333
36 AP2 0.679012 0.933333
37 APC 0.678571 0.933333
38 TAT 0.674419 0.933333
39 T99 0.674419 0.933333
40 A22 0.674157 0.958904
41 SRA 0.670886 0.894737
42 SRP 0.670455 0.883117
43 5AL 0.666667 0.906667
44 8LE 0.666667 0.871795
45 ADP BEF 0.662651 0.917808
46 ADP MG 0.662651 0.917808
47 ADQ 0.659341 0.92
48 A1R 0.659341 0.884615
49 A3R 0.659341 0.884615
50 QA7 0.655556 0.871795
51 JNT 0.652174 0.92
52 8LH 0.651685 0.883117
53 3OD 0.648936 0.92
54 BIS 0.648936 0.909091
55 5SV 0.648352 0.82716
56 V2G 0.647727 0.897436
57 9X8 0.645161 0.896104
58 OAD 0.645161 0.92
59 25L 0.642105 0.958904
60 AMO 0.641304 0.907895
61 ANP MG 0.640449 0.958904
62 8LQ 0.637363 0.883117
63 G5P 0.636364 0.897436
64 DLL 0.634409 0.906667
65 00A 0.634409 0.860759
66 AHX 0.634409 0.897436
67 RBY 0.632184 0.907895
68 ATP MG 0.632184 0.917808
69 APC MG 0.632184 0.893333
70 ADV 0.632184 0.907895
71 ADP PO3 0.632184 0.917808
72 NB8 0.631579 0.897436
73 OZV 0.630435 0.945205
74 8QN 0.630435 0.906667
75 OOB 0.630435 0.906667
76 25A 0.630435 0.945205
77 G3A 0.626263 0.897436
78 BEF ADP 0.625 0.893333
79 4AD 0.623656 0.896104
80 PAJ 0.623656 0.8625
81 LAD 0.621053 0.839506
82 ME8 0.614583 0.819277
83 1ZZ 0.614583 0.819277
84 TXA 0.614583 0.907895
85 GTA 0.613861 0.864198
86 9ZA 0.612903 0.909091
87 9ZD 0.612903 0.909091
88 KMQ 0.612245 0.907895
89 3UK 0.610526 0.894737
90 SON 0.604651 0.907895
91 ALF ADP 0.604396 0.848101
92 VO4 ADP 0.604396 0.92
93 WAQ 0.604167 0.860759
94 B5V 0.604167 0.883117
95 PR8 0.604167 0.829268
96 4UV 0.6 0.871795
97 GAP 0.6 0.87013
98 FYA 0.597938 0.881579
99 PTJ 0.597938 0.873418
100 LMS 0.597561 0.829268
101 UP5 0.596154 0.896104
102 FA5 0.59596 0.883117
103 PAP 0.595506 0.958333
104 A4P 0.59434 0.823529
105 XAH 0.59 0.841463
106 AFH 0.588235 0.8625
107 4UU 0.588235 0.871795
108 9SN 0.585859 0.85
109 2A5 0.58427 0.894737
110 T5A 0.583333 0.821429
111 DQV 0.582524 0.932432
112 NAI 0.580952 0.884615
113 B5M 0.58 0.871795
114 B5Y 0.58 0.871795
115 ITT 0.579545 0.917808
116 ATR 0.577778 0.944444
117 OMR 0.575472 0.831325
118 5AS 0.574713 0.781609
119 YLP 0.571429 0.8
120 48N 0.571429 0.873418
121 AP0 0.570093 0.873418
122 4TC 0.570093 0.873418
123 7D3 0.569767 0.881579
124 ADJ 0.568807 0.831325
125 DAL AMP 0.568421 0.881579
126 GNP 0.568421 0.922078
127 9GM 0.568421 0.922078
128 NAX 0.566038 0.851852
129 DND 0.566038 0.907895
130 6V0 0.566038 0.873418
131 4UW 0.566038 0.839506
132 TXD 0.566038 0.884615
133 ADN 0.565789 0.821918
134 XYA 0.565789 0.821918
135 RAB 0.565789 0.821918
136 AOC 0.564706 0.8
137 7D4 0.561798 0.881579
138 ADP BMA 0.561224 0.894737
139 TYM 0.560748 0.883117
140 TXE 0.560748 0.884615
141 GA7 0.557692 0.883117
142 YLC 0.555556 0.819277
143 YLB 0.555556 0.8
144 L3W 0.555556 0.907895
145 139 0.554545 0.851852
146 5N5 0.551282 0.797297
147 JB6 0.55 0.860759
148 LAQ 0.54717 0.819277
149 F2R 0.544643 0.843373
150 MYR AMP 0.544554 0.797619
151 A4D 0.544304 0.797297
152 5CD 0.544304 0.783784
153 80F 0.54386 0.821429
154 7MD 0.542857 0.864198
155 6AD 0.542553 0.886076
156 A2R 0.541667 0.958904
157 UPA 0.541284 0.884615
158 YLA 0.540541 0.8
159 BTX 0.539823 0.821429
160 COD 0.539823 0.793103
161 G5A 0.537634 0.781609
162 HFD 0.537634 0.921053
163 JSQ 0.537634 0.921053
164 CNA 0.535714 0.907895
165 AYB 0.535714 0.790698
166 3DH 0.535714 0.753247
167 BT5 0.535088 0.811765
168 ATP A 0.533981 0.905405
169 ATP A A A 0.533981 0.905405
170 IOT 0.531532 0.811765
171 MTA 0.53012 0.753247
172 3AM 0.529412 0.90411
173 A3P 0.52809 0.944444
174 NAD 0.526316 0.906667
175 PPS 0.526316 0.851852
176 NO7 0.525773 0.907895
177 EP4 0.52439 0.734177
178 7D5 0.52381 0.855263
179 AMP DBH 0.52381 0.87013
180 J7C 0.522727 0.75
181 H1Q 0.521739 0.88
182 A5A 0.520833 0.809524
183 EAD 0.520661 0.851852
184 TSB 0.520408 0.821429
185 AHZ 0.518519 0.797619
186 M2T 0.518072 0.716049
187 DTA 0.518072 0.766234
188 6RE 0.517241 0.740741
189 A3D 0.517241 0.894737
190 YLY 0.516949 0.790698
191 SSA 0.515464 0.802326
192 NA7 0.514852 0.933333
193 AR6 AR6 0.514019 0.893333
194 ARG AMP 0.514019 0.809524
195 7MC 0.513514 0.843373
196 A2P 0.511111 0.930556
197 VMS 0.510204 0.790698
198 54H 0.510204 0.790698
199 52H 0.510204 0.781609
200 TAD 0.509259 0.8625
201 NAQ 0.508333 0.85
202 A3N 0.505618 0.766234
203 CUU 0.505376 0.945205
204 AV2 0.505155 0.893333
205 53H 0.50505 0.781609
206 5CA 0.50505 0.802326
207 8X1 0.50505 0.755556
208 ARU 0.504951 0.839506
209 ZID 0.504132 0.894737
210 P1H 0.504 0.831325
211 AVV 0.5 0.873418
212 6MZ 0.5 0.905405
213 NAE 0.5 0.871795
214 3AT 0.5 0.945205
215 P5A 0.495146 0.747253
216 NSS 0.49505 0.802326
217 LSS 0.49505 0.764045
218 DSZ 0.49505 0.802326
219 N0B 0.491803 0.8
220 38V 0.491803 0.864198
221 ALF ADP 3PG 0.491071 0.817073
222 AF3 ADP 3PG 0.491071 0.817073
223 NVA LMS 0.490196 0.755556
224 O02 0.489583 0.922078
225 DAT 0.489362 0.881579
226 IMO 0.488889 0.90411
227 ZAS 0.488636 0.792208
228 FDA 0.488372 0.813953
229 NWW 0.487805 0.739726
230 D4F 0.487603 0.819277
231 NAJ PZO 0.487395 0.85
232 4TA 0.487179 0.788235
233 NAD TDB 0.486726 0.893333
234 NAD IBO 0.486726 0.893333
235 LPA AMP 0.486486 0.797619
236 DTP 0.484536 0.881579
237 V3L 0.484536 0.945205
238 GJV 0.483516 0.731707
239 S4M 0.483516 0.651685
240 DZD 0.483051 0.8625
241 2AM 0.482759 0.917808
242 5AD 0.481013 0.726027
243 KAA 0.480769 0.755556
244 GSU 0.480769 0.781609
245 NDE 0.480315 0.907895
246 M24 0.479339 0.851852
247 MAO 0.478261 0.761905
248 DSH 0.477778 0.707317
249 NEC 0.477778 0.727273
250 FAD 0.477273 0.831325
251 FAS 0.477273 0.831325
252 RGT 0.476636 0.933333
253 9K8 0.47619 0.698925
254 0WD 0.474576 0.897436
255 FNK 0.474074 0.786517
256 5X8 0.473684 0.74359
257 6FA 0.473282 0.821429
258 NDC 0.472868 0.85
259 FB0 0.472868 0.786517
260 YSA 0.472222 0.781609
261 LEU LMS 0.471154 0.733333
262 7DD 0.468085 0.958333
263 OVE 0.466667 0.881579
264 NWQ 0.465909 0.72
265 DZ4 0.464646 0.907895
266 MHZ 0.463158 0.701149
267 8PZ 0.462963 0.802326
268 AMP NAD 0.462185 0.881579
269 A3G 0.461538 0.779221
270 N5O 0.461538 0.74359
271 NAJ PYZ 0.459677 0.809524
272 6C6 0.459184 0.858974
273 B1U 0.458716 0.758242
274 LQJ 0.458716 0.893333
275 SFG 0.458333 0.730769
276 7D7 0.45679 0.723684
277 128 0.45614 0.8
278 SFD 0.455224 0.736842
279 DDS 0.454545 0.855263
280 GDP 0.454545 0.896104
281 6IA 0.454545 0.817073
282 NJP 0.453782 0.921053
283 ODP 0.453782 0.886076
284 7DT 0.453608 0.958333
285 J4G 0.45283 0.896104
286 A7D 0.452632 0.75641
287 Z5A 0.452381 0.802326
288 WSA 0.452174 0.790698
289 N5A 0.451613 0.717949
290 7C5 0.45045 0.797468
291 K3K 0.449541 0.782051
292 FAY 0.449275 0.841463
293 NDP 0.449153 0.897436
294 SA8 0.44898 0.690476
295 A5D 0.44898 0.766234
296 71V 0.446809 0.884615
297 GGZ 0.446602 0.804878
298 RFL 0.446043 0.802326
299 2SA 0.445545 0.907895
300 SAH 0.444444 0.725
301 SAI 0.444444 0.716049
302 GP3 0.444444 0.897436
303 PO4 PO4 A A A A PO4 0.443396 0.878378
304 QXG 0.443396 0.77907
305 4YB 0.442478 0.764045
306 QXP 0.442308 0.788235
307 K3E 0.441441 0.772152
308 S7M 0.441176 0.674419
309 SMM 0.441176 0.670455
310 GTP 0.441176 0.896104
311 V47 0.441176 0.763158
312 Y3J 0.440476 0.706667
313 SAM 0.44 0.674419
314 649 0.439655 0.747253
315 12D 0.438596 0.809524
316 A3S 0.4375 0.789474
317 NPW 0.436975 0.864198
318 GCP 0.436893 0.873418
319 EEM 0.435644 0.674419
320 AAT 0.435644 0.690476
321 GNH 0.435644 0.909091
322 ETB 0.435484 0.813953
323 DCA 0.435484 0.804598
324 KOY 0.434783 0.782051
325 N6P 0.433962 0.890411
326 NZQ 0.433333 0.886076
327 TXP 0.433333 0.897436
328 PGS 0.43299 0.860759
329 APU 0.432203 0.871795
330 PUA 0.432 0.8625
331 62F 0.431655 0.841463
332 F2N 0.431507 0.795455
333 DA 0.430108 0.855263
334 D5M 0.430108 0.855263
335 J7V 0.429688 0.813953
336 0T1 0.428571 0.804598
337 A3T 0.428571 0.8
338 COA 0.428571 0.804598
339 NIA 0.428571 0.848101
340 6K6 0.428571 0.905405
341 P5F 0.427586 0.804598
342 R2V 0.425926 0.788235
343 CZF 0.425743 0.906667
344 NX8 0.425743 0.698795
345 AAM 0.425532 0.944444
346 KYB 0.424528 0.714286
347 0UM 0.424528 0.682353
348 8Q2 0.423729 0.775281
349 G1R 0.423077 0.884615
350 AMZ 0.422222 0.891892
351 C2R 0.422222 0.88
352 QBQ 0.421569 0.883117
353 IDP 0.42 0.894737
354 K2W 0.419643 0.722892
355 KY2 0.419048 0.714286
356 GSP 0.419048 0.851852
357 1DG 0.418605 0.897436
358 COS 0.418605 0.786517
359 CAO 0.418605 0.777778
360 DG1 0.418605 0.897436
361 30N 0.418605 0.736842
362 AMX 0.418605 0.813953
363 KY5 0.418182 0.707317
364 TM1 0.418182 0.797619
365 9BG 0.418033 0.873418
366 A6D 0.416667 0.746988
367 K15 0.416667 0.666667
368 V1N 0.415929 0.893333
369 SCO 0.415385 0.804598
370 CMX 0.415385 0.804598
371 GEK 0.415094 0.719512
372 NHD 0.414634 0.881579
373 XNP 0.414634 0.851852
374 K38 0.414414 0.759494
375 9JJ 0.413793 0.841463
376 AIR 0.413793 0.876712
377 COK 0.413534 0.786517
378 K2K 0.412844 0.719512
379 G2R 0.412844 0.8625
380 KY8 0.412844 0.710843
381 FAM 0.412214 0.786517
382 FCX 0.412214 0.777778
383 ACO 0.412214 0.777778
384 KL2 0.411111 0.815789
385 NAP 0.410853 0.92
386 NWZ 0.41 0.686747
387 CNV FAD 0.409722 0.775281
388 FA9 0.409396 0.843373
389 SXZ 0.409091 0.694118
390 K2R 0.409091 0.857143
391 O05 0.409091 0.823529
392 HAX 0.409091 0.806818
393 TAP 0.407692 0.884615
394 62X 0.407407 0.651685
395 2MC 0.407407 0.752688
396 K2H 0.407407 0.7375
397 GKE 0.40708 0.8625
398 GDD 0.40708 0.8625
399 GDC 0.40708 0.8625
400 KYE 0.40708 0.697674
401 FYN 0.406015 0.804598
402 3KK 0.406015 0.786517
403 NVA 2AD 0.405941 0.740741
404 KXW 0.405172 0.690476
405 PLP AAD 0.404762 0.736264
406 NA0 0.40458 0.907895
407 101 0.404255 0.855263
408 G 0.40404 0.883117
409 5GP 0.40404 0.883117
410 FAJ 0.403974 0.811765
411 HDV 0.403846 0.87013
412 MGP 0.403846 0.8625
413 MCD 0.402985 0.786517
414 OXK 0.402985 0.786517
415 YZS 0.402985 0.714286
416 KGP 0.402985 0.714286
417 SOP 0.402985 0.786517
418 CA6 0.402985 0.714286
419 3AD 0.402299 0.783784
420 S8M 0.401869 0.78481
421 YE1 0.40146 0.795455
422 2VA 0.4 0.779221
423 6G0 0.4 0.8625
424 NMX 0.4 0.782609
425 CO6 0.4 0.786517
426 1VU 0.4 0.777778
427 GMV 0.4 0.873418
428 7RP 0.4 0.902778
429 CMC 0.4 0.786517
Ligand no: 2; Ligand: ARG; Similar ligands found: 47
No: Ligand ECFP6 Tc MDL keys Tc
1 DAR 1 1
2 ARG 1 1
3 CIR 0.735294 0.763158
4 AAR 0.705882 0.783784
5 ILO 0.615385 0.783784
6 3AR 0.595238 0.891892
7 4JK 0.585366 0.789474
8 NMM 0.585366 0.888889
9 HAR 0.585366 0.780488
10 VUR 0.585366 0.810811
11 VIO 0.581395 0.769231
12 WT2 0.571429 0.805556
13 DA2 0.55814 0.744186
14 2YH 0.545455 0.65
15 3KJ 0.545455 0.680851
16 2MR 0.545455 0.864865
17 1KJ 0.533333 0.744186
18 JM2 0.533333 0.731707
19 NRG 0.521739 0.622642
20 RPI 0.521739 0.64
21 2YJ 0.521739 0.619048
22 API 0.515152 0.611111
23 LN6 0.510638 0.725
24 JM7 0.5 0.731707
25 ARG VAL 0.5 0.744186
26 HRG 0.5 0.941176
27 LYS ARG LYS ARG LYS ARG LYS ARG 0.5 0.848485
28 AS1 0.489796 0.8
29 D20 0.489796 0.744186
30 2KJ 0.489796 0.727273
31 ORN 0.472222 0.757576
32 JM4 0.470588 0.697674
33 JM6 0.470588 0.697674
34 JM8 0.470588 0.714286
35 MLZ 0.463415 0.65
36 ARG ASP 0.461538 0.744186
37 JM5 0.461538 0.714286
38 ARG GLU 0.45283 0.761905
39 DLY 0.447368 0.735294
40 DAB 0.441176 0.685714
41 LYS 0.435897 0.764706
42 0TF 0.428571 0.619048
43 2YG 0.42 0.619048
44 ALA ARG 0.42 0.780488
45 PG3 0.416667 0.756757
46 6CL 0.414634 0.638889
47 BEZ NLE LYS ARG OAR 0.413793 0.75
Similar Ligands (3D)
Ligand no: 1; Ligand: ANP; Similar ligands found: 33
No: Ligand Similarity coefficient
1 ADP AF3 0.9867
2 ADP VO4 0.9840
3 ADP ALF 0.9835
4 BEF GDP 0.9733
5 GDP BEF 0.9732
6 ALF GDP 0.9572
7 DBG 0.9557
8 GDP ALF 0.9557
9 GDP AF3 0.9523
10 UTP 0.9434
11 DGT 0.9413
12 CTP 0.9332
13 UNP 0.9314
14 GDP MG 0.9298
15 8DG 0.9119
16 MGT 0.9080
17 TTP 0.9060
18 DUP 0.9039
19 GH3 0.8961
20 Y9Z 0.8940
21 MGO 0.8925
22 2TM 0.8903
23 2KH 0.8853
24 DUT 0.8825
25 DUT MG 0.8783
26 M7G 0.8756
27 GTP MG 0.8746
28 DCP 0.8734
29 DGI 0.8732
30 ALF 5GP 0.8646
31 RSN 0.8624
32 DCT 0.8623
33 G2P 0.8610
Ligand no: 2; Ligand: ARG; Similar ligands found: 663
No: Ligand Similarity coefficient
1 2M7 1.0000
2 GGB 0.9987
3 MLY 0.9957
4 NPI 0.9877
5 IAR 0.9808
6 6HN 0.9763
7 EXY 0.9757
8 DHH 0.9716
9 ABH 0.9712
10 JX7 0.9650
11 ZZU 0.9621
12 26P 0.9575
13 L06 0.9562
14 LVD 0.9550
15 NNH 0.9549
16 M3L 0.9547
17 AHL 0.9544
18 EGV 0.9522
19 HOC 0.9487
20 ENW 0.9464
21 2FM 0.9456
22 4DI 0.9455
23 ENV 0.9446
24 LPB 0.9434
25 E8U 0.9434
26 PML 0.9432
27 FB6 0.9418
28 CLT 0.9417
29 2NP 0.9415
30 11C 0.9411
31 GVA 0.9410
32 UN1 0.9406
33 NOT 0.9392
34 4ZD 0.9385
35 9YT 0.9379
36 SZ7 0.9358
37 AHN 0.9352
38 011 0.9351
39 TEG 0.9349
40 OOG 0.9343
41 4TB 0.9342
42 ONH 0.9341
43 58X 0.9339
44 OCA 0.9336
45 M3P 0.9334
46 SLZ 0.9329
47 Z70 0.9329
48 HFA 0.9326
49 2OR 0.9326
50 5AB 0.9322
51 S2C 0.9322
52 P80 0.9321
53 XRS 0.9321
54 LPA 0.9316
55 N8C 0.9313
56 ALY 0.9308
57 FK8 0.9307
58 PHE 0.9305
59 XRX 0.9303
60 MF3 0.9298
61 PBA 0.9284
62 LYN 0.9275
63 A51 0.9262
64 8AC 0.9262
65 N9J 0.9260
66 1HS 0.9259
67 NFZ 0.9256
68 9J6 0.9255
69 64Z 0.9254
70 DHC 0.9247
71 LUQ 0.9238
72 KAP 0.9233
73 GRQ 0.9231
74 DDK 0.9230
75 NFA 0.9227
76 J9Y 0.9226
77 MHN 0.9223
78 6C4 0.9221
79 AOY 0.9217
80 HIC 0.9217
81 7OD 0.9216
82 GB5 0.9212
83 M1T 0.9212
84 HCI 0.9211
85 KDG 0.9210
86 KNA 0.9208
87 DNN 0.9207
88 TYR 0.9205
89 HJD 0.9205
90 F98 0.9205
91 DA3 0.9204
92 1N5 0.9202
93 Q9Z 0.9201
94 YZM 0.9198
95 CXP 0.9196
96 AG2 0.9195
97 DKA 0.9193
98 LZ5 0.9190
99 SB7 0.9188
100 DXG 0.9185
101 1PS 0.9183
102 DZA 0.9182
103 4YZ 0.9182
104 PFF 0.9180
105 DTY 0.9179
106 5OY 0.9175
107 YOF 0.9174
108 KPV 0.9173
109 CCU 0.9173
110 DAH 0.9171
111 7XA 0.9171
112 FXY 0.9169
113 3YP 0.9168
114 11X 0.9168
115 6C5 0.9166
116 5PV 0.9163
117 M6H 0.9161
118 EN1 0.9161
119 RGP 0.9159
120 PRO GLY 0.9159
121 DDW 0.9158
122 GLR 0.9158
123 3H2 0.9154
124 XI7 0.9153
125 TCA 0.9153
126 HC4 0.9152
127 ODI 0.9149
128 3GZ 0.9149
129 B3U 0.9142
130 T03 0.9141
131 O45 0.9141
132 AE3 0.9140
133 OC9 0.9137
134 PO6 0.9137
135 HLP 0.9134
136 PBN 0.9132
137 DLT 0.9131
138 P81 0.9131
139 P7Y 0.9129
140 5KJ 0.9128
141 G3M 0.9126
142 TB8 0.9126
143 6C9 0.9125
144 HGA 0.9124
145 HPP 0.9121
146 4TP 0.9120
147 C82 0.9120
148 P93 0.9119
149 AHC 0.9117
150 0L1 0.9115
151 IVL 0.9115
152 HPL 0.9113
153 6FG 0.9113
154 E79 0.9112
155 650 0.9112
156 SPD 0.9112
157 TZM 0.9109
158 PPT 0.9109
159 DER 0.9106
160 KPC 0.9105
161 DIR 0.9103
162 XOG 0.9103
163 CUW 0.9093
164 TZP 0.9090
165 1BN 0.9090
166 NSD 0.9084
167 OJD 0.9083
168 JFM 0.9082
169 S2P 0.9081
170 4BF 0.9080
171 HIS 0.9079
172 ENO 0.9079
173 IYR 0.9079
174 2JJ 0.9078
175 PHI 0.9073
176 0A9 0.9068
177 J4K 0.9065
178 DIA 0.9064
179 AOT 0.9064
180 LL2 0.9063
181 TYC 0.9063
182 3VQ 0.9061
183 S0W 0.9061
184 MJW 0.9060
185 PPY 0.9059
186 EYJ 0.9058
187 OYA 0.9058
188 Q06 0.9055
189 KPA 0.9054
190 XIZ 0.9054
191 SB9 0.9052
192 MD6 0.9050
193 RP3 0.9050
194 5LD 0.9050
195 S8V 0.9046
196 TYE 0.9044
197 S7D 0.9037
198 848 0.9036
199 DPN 0.9035
200 2J3 0.9034
201 I58 0.9033
202 7C3 0.9030
203 GZ2 0.9030
204 KTA 0.9029
205 D10 0.9028
206 GAE 0.9028
207 7BC 0.9027
208 BNF 0.9024
209 F90 0.9023
210 KQY 0.9022
211 TOH 0.9021
212 4LW 0.9020
213 37E 0.9018
214 5TO 0.9013
215 SHV 0.9013
216 NWH 0.9012
217 6MW 0.9012
218 G14 0.9010
219 EQA 0.9010
220 ACA 0.9009
221 4LV 0.9008
222 IJ6 0.9005
223 1H1 0.9002
224 GO2 0.9000
225 AZM 0.8999
226 1L5 0.8998
227 FOM 0.8997
228 ISA 0.8996
229 C53 0.8995
230 HX8 0.8988
231 ODK 0.8987
232 KLS 0.8986
233 4BX 0.8984
234 HNL 0.8984
235 R10 0.8983
236 3PG 0.8981
237 DHM 0.8981
238 HPO 0.8981
239 7UC 0.8978
240 3QO 0.8978
241 SHI 0.8978
242 BRH 0.8978
243 3IP 0.8977
244 GLY GLY GLY 0.8975
245 HSA 0.8973
246 PH3 0.8973
247 B40 0.8972
248 QFJ 0.8972
249 5DL 0.8972
250 MES 0.8969
251 HG3 0.8969
252 AKG 0.8966
253 SEP 0.8965
254 HL4 0.8965
255 RA7 0.8964
256 8SZ 0.8963
257 4Z0 0.8962
258 ZZA 0.8962
259 SOJ 0.8961
260 7R4 0.8961
261 NMH 0.8960
262 DXP 0.8960
263 492 0.8958
264 PA5 0.8957
265 SSC 0.8957
266 DEZ 0.8956
267 0A1 0.8956
268 YIE 0.8955
269 S0A 0.8952
270 MMS 0.8949
271 HPN 0.8947
272 9GB 0.8946
273 2HC 0.8944
274 DYT 0.8941
275 HXY 0.8941
276 4FE 0.8940
277 TPM 0.8939
278 4XF 0.8937
279 268 0.8936
280 FER 0.8935
281 JF5 0.8935
282 QH3 0.8931
283 ABF 0.8931
284 X48 0.8928
285 S8D 0.8927
286 EQW 0.8925
287 KLE 0.8925
288 BSA 0.8924
289 GJK 0.8922
290 F06 0.8921
291 LLH 0.8920
292 VC3 0.8919
293 JPQ 0.8918
294 6Q3 0.8918
295 ALE 0.8915
296 36M 0.8915
297 D4G 0.8914
298 ALA GLU 0.8913
299 258 0.8911
300 GLU 0.8911
301 0NX 0.8909
302 92G 0.8909
303 TBJ 0.8909
304 7MW 0.8908
305 GGG 0.8908
306 R9J 0.8907
307 DI6 0.8907
308 MEQ 0.8906
309 PAU 0.8905
310 RQD 0.8904
311 D8Q 0.8904
312 6HO 0.8904
313 GNW 0.8903
314 9VQ 0.8903
315 13P 0.8903
316 9C2 0.8902
317 YIP 0.8900
318 BZQ 0.8900
319 TMG 0.8899
320 3VW 0.8898
321 M5E 0.8897
322 M74 0.8896
323 2FX 0.8893
324 PRA 0.8892
325 OGA 0.8892
326 IPO 0.8892
327 GCO 0.8891
328 HJH 0.8890
329 QUS 0.8890
330 A5E 0.8887
331 B41 0.8886
332 GOE 0.8886
333 BL0 0.8884
334 BHU 0.8882
335 I2E 0.8880
336 E0O 0.8879
337 0XR 0.8878
338 N6C 0.8877
339 HX4 0.8877
340 3CX 0.8875
341 SNR 0.8875
342 YPN 0.8873
343 M5B 0.8872
344 CUQ 0.8871
345 K6V 0.8868
346 5DS 0.8868
347 5XA 0.8867
348 KYN 0.8866
349 YIH 0.8865
350 5O5 0.8865
351 GVY 0.8865
352 795 0.8864
353 LT1 0.8864
354 4KJ 0.8862
355 7O4 0.8861
356 DMA 0.8861
357 Y3L 0.8860
358 56D 0.8860
359 S8G 0.8858
360 AT3 0.8857
361 3OL 0.8855
362 3OM 0.8855
363 14W 0.8854
364 PMV 0.8854
365 R5P 0.8853
366 263 0.8853
367 1X4 0.8850
368 R2P 0.8850
369 6XA 0.8849
370 6C8 0.8849
371 SSB 0.8848
372 S0F 0.8847
373 FHC 0.8847
374 BP7 0.8846
375 DX5 0.8846
376 8CC 0.8845
377 61M 0.8845
378 1YO 0.8845
379 LXP 0.8845
380 I38 0.8845
381 6FR 0.8844
382 OHJ 0.8844
383 TIH 0.8844
384 47V 0.8842
385 4FP 0.8842
386 GLN 0.8841
387 FHV 0.8838
388 ONL 0.8837
389 RAT 0.8837
390 6ZX 0.8835
391 P58 0.8834
392 A5P 0.8833
393 RE4 0.8832
394 IAC 0.8830
395 XCG 0.8829
396 ATX 0.8829
397 FB5 0.8829
398 CS2 0.8827
399 G3P 0.8827
400 7VP 0.8827
401 BVS 0.8826
402 5SP 0.8826
403 H35 0.8825
404 QIV 0.8825
405 IPE 0.8824
406 RP5 0.8823
407 LX1 0.8823
408 CCD 0.8820
409 D3G 0.8818
410 NYL 0.8817
411 ASF 0.8816
412 XDE 0.8816
413 54F 0.8815
414 EOU 0.8815
415 68B 0.8812
416 MVH 0.8812
417 E4P 0.8809
418 AMQ 0.8809
419 2D2 0.8808
420 Q04 0.8807
421 G3H 0.8807
422 M75 0.8805
423 HHI 0.8802
424 FZM 0.8802
425 NTU 0.8800
426 DED 0.8800
427 M45 0.8799
428 ZIP 0.8799
429 SME 0.8799
430 HPV 0.8798
431 TRP 0.8798
432 CXH 0.8797
433 HSX 0.8795
434 RES 0.8794
435 L22 0.8794
436 QME 0.8793
437 GB4 0.8790
438 6P3 0.8790
439 XQI 0.8789
440 2IT 0.8789
441 GGL 0.8789
442 N7I 0.8788
443 1OV 0.8787
444 PTB 0.8786
445 BZM 0.8786
446 9BF 0.8786
447 3XH 0.8785
448 2FT 0.8784
449 0ON 0.8783
450 PLP 0.8781
451 A3M 0.8781
452 JMG 0.8780
453 DHI 0.8780
454 9B3 0.8780
455 MSL 0.8780
456 DGL 0.8779
457 22F 0.8778
458 X1R 0.8777
459 NF3 0.8777
460 0OL 0.8776
461 HL6 0.8775
462 4CF 0.8771
463 S2G 0.8771
464 0K7 0.8770
465 P3S 0.8769
466 1VK 0.8765
467 363 0.8764
468 E3X 0.8762
469 CBE 0.8761
470 NK5 0.8759
471 27K 0.8759
472 BNL 0.8759
473 5H6 0.8758
474 BPW 0.8757
475 YE6 0.8755
476 MPV 0.8755
477 FWD 0.8755
478 1A5 0.8754
479 A5H 0.8754
480 Y4L 0.8754
481 6L6 0.8753
482 9JT 0.8753
483 N2Y 0.8752
484 EYV 0.8751
485 5WN 0.8751
486 LR2 0.8750
487 6J5 0.8750
488 GUA 0.8747
489 B3M 0.8746
490 WA2 0.8744
491 5OO 0.8743
492 S0D 0.8743
493 JCZ 0.8742
494 FF2 0.8741
495 KTJ 0.8740
496 TX4 0.8739
497 SYM 0.8739
498 5WZ 0.8736
499 DGN 0.8735
500 3VX 0.8735
501 TL6 0.8733
502 IOP 0.8733
503 IP8 0.8731
504 0QA 0.8731
505 9ON 0.8731
506 A8K 0.8729
507 3HG 0.8729
508 LDP 0.8729
509 GPJ 0.8728
510 GPF 0.8728
511 S6P 0.8727
512 5RP 0.8727
513 152 0.8727
514 D2G 0.8725
515 1Z6 0.8725
516 SOL 0.8725
517 FZ3 0.8724
518 U4G 0.8723
519 PLR 0.8721
520 2HG 0.8717
521 CFA 0.8717
522 9SE 0.8717
523 8GL 0.8716
524 ZRK 0.8716
525 MNP 0.8713
526 J9N 0.8712
527 6SD 0.8712
528 GP9 0.8711
529 KMY 0.8710
530 OCT 0.8710
531 URO 0.8708
532 SOR 0.8707
533 KMH 0.8705
534 WA1 0.8705
535 ERZ 0.8703
536 TLM 0.8702
537 0OY 0.8701
538 LO1 0.8700
539 HWD 0.8700
540 LSQ 0.8700
541 4Z3 0.8699
542 DHY 0.8698
543 RKV 0.8698
544 MHO 0.8697
545 LJ1 0.8696
546 3C4 0.8696
547 3VS 0.8695
548 XX3 0.8695
549 F6R 0.8694
550 N91 0.8694
551 HNM 0.8692
552 CPZ 0.8692
553 XDK 0.8691
554 3S5 0.8691
555 50C 0.8690
556 BQ2 0.8690
557 FCD 0.8687
558 MUK 0.8687
559 JAH 0.8683
560 41K 0.8682
561 M6R 0.8682
562 IPR 0.8681
563 PGH 0.8681
564 PAN 0.8681
565 MT2 0.8680
566 MSR 0.8678
567 8CV 0.8677
568 OKP 0.8674
569 SNU 0.8673
570 D1G 0.8672
571 1HR 0.8669
572 V15 0.8669
573 K7M 0.8669
574 CIY 0.8667
575 U13 0.8667
576 3CR 0.8666
577 129 0.8666
578 3D3 0.8659
579 ZEA 0.8655
580 CHH 0.8655
581 PC 0.8655
582 CCE 0.8653
583 F18 0.8652
584 1GP 0.8651
585 X6P 0.8649
586 AEH 0.8648
587 2ED 0.8648
588 H4E 0.8645
589 CK2 0.8645
590 HE8 0.8642
591 TID 0.8642
592 KTW 0.8642
593 VM1 0.8641
594 EIP 0.8641
595 HHH 0.8640
596 IOS 0.8637
597 0SY 0.8636
598 DST 0.8636
599 ALA ALA 0.8635
600 JZA 0.8634
601 0OP 0.8633
602 EGR 0.8632
603 FPL 0.8631
604 ISY 0.8630
605 RUJ 0.8630
606 ESX 0.8629
607 A5Q 0.8628
608 5VU 0.8627
609 D9Z 0.8626
610 B21 0.8626
611 MET 0.8623
612 TAG 0.8622
613 AAN 0.8620
614 GLO 0.8618
615 YTX 0.8616
616 RNO 0.8615
617 IWT 0.8614
618 XEN 0.8612
619 F4E 0.8611
620 ICT 0.8608
621 J6W 0.8607
622 36Y 0.8605
623 OJM 0.8605
624 DTR 0.8604
625 G6Q 0.8601
626 G6P 0.8599
627 C5A 0.8599
628 PSE 0.8598
629 A29 0.8598
630 RTK 0.8597
631 ESP 0.8595
632 80G 0.8590
633 AEF 0.8589
634 F63 0.8589
635 STT 0.8588
636 SNO 0.8588
637 BZE 0.8587
638 K6H 0.8586
639 SX2 0.8586
640 AMH 0.8584
641 ESI 0.8581
642 3LJ 0.8580
643 55D 0.8580
644 6TZ 0.8579
645 78Y 0.8577
646 EVF 0.8576
647 1A7 0.8569
648 428 0.8565
649 LNR 0.8564
650 8YH 0.8562
651 NM3 0.8562
652 9ZE 0.8561
653 R20 0.8557
654 7EH 0.8550
655 YTZ 0.8550
656 6PG 0.8548
657 DTB 0.8546
658 M1Z 0.8545
659 AFS 0.8534
660 6KT 0.8531
661 0F3 0.8517
662 AGP 0.8514
663 CWD 0.8510
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4D57; Ligand: ARG AMP; Similar sites found with APoc: 2
This union binding pocket(no: 1) in the query (biounit: 4d57.bio1) has 37 residues
No: Leader PDB Ligand Sequence Similarity
1 6IJB AMP 38.7755
2 6IJB A8C 38.7755
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