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Receptor
PDB id Resolution Class Description Source Keywords
4D52 1.76 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF FUCOSE BINDING LECTIN FROM ASPERGILLUS FUMIGATUS (AFL) IN COMPLEX WITH L-GALACTOPYRANOSE. ASPERGILLUS FUMIGATUS SUGAR BINDING PROTEIN
Ref.: STRUCTURAL INSIGHTS INTO ASPERGILLUS FUMIGATUS LECT SPECIFICITY: AFL BINDING SITES ARE FUNCTIONALLY NON EQUIVALENT. ACTA CRYSTALLOGR.,SECT.D V. 71 442 2015
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NA C:1318;
D:1317;
B:1318;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
submit data
22.99 Na [Na+]
GIV D:2320;
C:2322;
A:2319;
C:2327;
D:1318;
D:2324;
B:2319;
A:2316;
C:2319;
B:2326;
B:2322;
A:2322;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
180.156 C6 H12 O6 C([C@...
GXL A:1318;
D:1319;
D:1320;
A:1319;
C:1319;
C:1322;
C:1327;
B:1321;
A:1322;
B:1322;
C:1321;
A:1316;
B:1319;
D:1324;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
180.156 C6 H12 O6 C([C@...
PGE C:1325;
D:1322;
B:1324;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
150.173 C6 H14 O4 C(COC...
PG4 A:1320;
D:1321;
C:1323;
B:1323;
C:1324;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
submit data
194.226 C8 H18 O5 C(COC...
PEG B:1325;
C:1326;
C:1320;
A:1321;
A:1317;
B:1320;
D:1323;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
submit data
106.12 C4 H10 O3 C(COC...
ZN B:1317;
Part of Protein;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4D52 1.76 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF FUCOSE BINDING LECTIN FROM ASPERGILLUS FUMIGATUS (AFL) IN COMPLEX WITH L-GALACTOPYRANOSE. ASPERGILLUS FUMIGATUS SUGAR BINDING PROTEIN
Ref.: STRUCTURAL INSIGHTS INTO ASPERGILLUS FUMIGATUS LECT SPECIFICITY: AFL BINDING SITES ARE FUNCTIONALLY NON EQUIVALENT. ACTA CRYSTALLOGR.,SECT.D V. 71 442 2015
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 4D52 - GIV C6 H12 O6 C([C@H]1[C....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 4D52 - GIV C6 H12 O6 C([C@H]1[C....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 4D52 - GIV C6 H12 O6 C([C@H]1[C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GIV; Similar ligands found: 142
No: Ligand ECFP6 Tc MDL keys Tc
1 WOO 1 1
2 GLC 1 1
3 BGC 1 1
4 ALL 1 1
5 BMA 1 1
6 GXL 1 1
7 GIV 1 1
8 GAL 1 1
9 MAN 1 1
10 GLA 1 1
11 Z6J 0.653846 0.866667
12 32O 0.653846 0.866667
13 RIB 0.653846 0.866667
14 FUB 0.653846 0.866667
15 AHR 0.653846 0.866667
16 MLB 0.511628 0.848485
17 GLC GLC 0.511628 0.848485
18 BGC GLC 0.511628 0.848485
19 BGC GLA 0.511628 0.848485
20 GLA BMA 0.511628 0.848485
21 MAN BMA 0.511628 0.848485
22 BMA GLA 0.511628 0.848485
23 GLA BGC 0.511628 0.848485
24 MAN MAN 0.511628 0.848485
25 GLA GLC 0.511628 0.848485
26 BMA MAN 0.511628 0.848485
27 GAL GLC 0.511628 0.848485
28 GAL GAL 0.511628 0.848485
29 LAK 0.511628 0.848485
30 GLC BGC 0.511628 0.848485
31 YDR 0.5 0.8
32 GLC GLC GLC GLC BGC 0.488889 0.848485
33 GLC GLC GLC 0.488889 0.848485
34 MAN MAN MAN 0.488889 0.848485
35 BMA MAN MAN 0.488889 0.848485
36 GLC GLC GLC GLC GLC BGC 0.488889 0.848485
37 EMZ 0.472222 0.794118
38 BG6 0.461538 0.675
39 BGP 0.461538 0.675
40 G6P 0.461538 0.675
41 M6P 0.461538 0.675
42 M6D 0.461538 0.675
43 A6P 0.461538 0.675
44 GAF 0.457143 0.875
45 SHG 0.457143 0.875
46 2FG 0.457143 0.875
47 G2F 0.457143 0.875
48 2H5 0.457143 0.875
49 GCS 0.457143 0.777778
50 1GN 0.457143 0.777778
51 X6X 0.457143 0.777778
52 PA1 0.457143 0.777778
53 95Z 0.457143 0.777778
54 G3F 0.457143 0.875
55 NGR 0.454545 0.848485
56 MAL 0.454545 0.848485
57 MAN GLC 0.454545 0.848485
58 GAL BGC 0.454545 0.848485
59 GLA GLA 0.454545 0.848485
60 BGC BMA 0.454545 0.848485
61 M3M 0.454545 0.848485
62 GLA GAL 0.454545 0.848485
63 MAB 0.454545 0.848485
64 GLC GAL 0.454545 0.848485
65 B2G 0.454545 0.848485
66 LBT 0.454545 0.848485
67 BMA GAL 0.454545 0.848485
68 LAT 0.454545 0.848485
69 BGC GAL 0.454545 0.848485
70 CBI 0.454545 0.848485
71 CBK 0.454545 0.848485
72 N9S 0.454545 0.848485
73 LB2 0.454545 0.848485
74 3MG 0.444444 0.875
75 TCB 0.444444 0.8
76 GLC SGC 0.444444 0.8
77 YIO 0.441176 0.870968
78 2GS 0.432432 0.875
79 2M4 0.431818 0.848485
80 AHR AHR 0.428571 0.764706
81 GLF 0.428571 0.84375
82 FUB AHR 0.428571 0.764706
83 MAN BMA BMA 0.416667 0.848485
84 BMA MAN BMA 0.416667 0.848485
85 CTR 0.416667 0.848485
86 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.416667 0.848485
87 GLA GAL BGC 0.416667 0.848485
88 CE5 0.416667 0.848485
89 MLR 0.416667 0.848485
90 CE6 0.416667 0.848485
91 MT7 0.416667 0.848485
92 BMA BMA BMA 0.416667 0.848485
93 GLC BGC BGC BGC BGC 0.416667 0.848485
94 MAN MAN BMA BMA BMA BMA 0.416667 0.848485
95 BGC BGC BGC BGC BGC 0.416667 0.848485
96 BGC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
97 BGC GLC GLC 0.416667 0.848485
98 BMA BMA BMA BMA BMA 0.416667 0.848485
99 MAN BMA BMA BMA BMA 0.416667 0.848485
100 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
101 GLC BGC BGC BGC BGC BGC 0.416667 0.848485
102 MAN BMA BMA BMA BMA BMA 0.416667 0.848485
103 BGC BGC BGC BGC BGC BGC 0.416667 0.848485
104 BGC GLC GLC GLC 0.416667 0.848485
105 BGC BGC BGC GLC 0.416667 0.848485
106 CTT 0.416667 0.848485
107 GLA GAL GLC 0.416667 0.848485
108 MTT 0.416667 0.848485
109 GLC BGC BGC BGC 0.416667 0.848485
110 GLC GLC BGC 0.416667 0.848485
111 CEY 0.416667 0.848485
112 B4G 0.416667 0.848485
113 CE8 0.416667 0.848485
114 BMA BMA BMA BMA BMA BMA 0.416667 0.848485
115 GAL FUC 0.416667 0.848485
116 DXI 0.416667 0.848485
117 GLC BGC GLC 0.416667 0.848485
118 CT3 0.416667 0.848485
119 GAL GAL GAL 0.416667 0.848485
120 GLC GLC GLC GLC GLC 0.416667 0.848485
121 BGC BGC BGC BGC 0.416667 0.848485
122 BGC BGC BGC 0.416667 0.848485
123 BGC BGC GLC 0.416667 0.848485
124 CEX 0.416667 0.848485
125 GLC GAL GAL 0.416667 0.848485
126 BGC GLC GLC GLC GLC 0.416667 0.848485
127 GLC BGC BGC 0.416667 0.848485
128 GS1 GLC GS1 0.408163 0.8
129 SGC SGC BGC 0.408163 0.8
130 BGC BGC BGC GLC BGC BGC 0.408163 0.848485
131 GLC BGC BGC BGC BGC BGC BGC 0.408163 0.848485
132 1LL 0.405405 0.771429
133 TDG 0.405405 0.771429
134 TRE 0.405405 0.848485
135 NDG 0.404762 0.7
136 NGA 0.404762 0.7
137 NAG 0.404762 0.7
138 HSQ 0.404762 0.7
139 A2G 0.404762 0.7
140 BM3 0.404762 0.7
141 FUB AHR AHR 0.4 0.764706
142 AHR AHR AHR AHR AHR AHR 0.4 0.764706
Ligand no: 2; Ligand: GXL; Similar ligands found: 142
No: Ligand ECFP6 Tc MDL keys Tc
1 WOO 1 1
2 GLC 1 1
3 BGC 1 1
4 ALL 1 1
5 BMA 1 1
6 GXL 1 1
7 GIV 1 1
8 GAL 1 1
9 MAN 1 1
10 GLA 1 1
11 Z6J 0.653846 0.866667
12 32O 0.653846 0.866667
13 RIB 0.653846 0.866667
14 FUB 0.653846 0.866667
15 AHR 0.653846 0.866667
16 MLB 0.511628 0.848485
17 GLC GLC 0.511628 0.848485
18 BGC GLC 0.511628 0.848485
19 BGC GLA 0.511628 0.848485
20 GLA BMA 0.511628 0.848485
21 MAN BMA 0.511628 0.848485
22 BMA GLA 0.511628 0.848485
23 GLA BGC 0.511628 0.848485
24 MAN MAN 0.511628 0.848485
25 GLA GLC 0.511628 0.848485
26 BMA MAN 0.511628 0.848485
27 GAL GLC 0.511628 0.848485
28 GAL GAL 0.511628 0.848485
29 LAK 0.511628 0.848485
30 GLC BGC 0.511628 0.848485
31 YDR 0.5 0.8
32 GLC GLC GLC GLC BGC 0.488889 0.848485
33 GLC GLC GLC 0.488889 0.848485
34 MAN MAN MAN 0.488889 0.848485
35 BMA MAN MAN 0.488889 0.848485
36 GLC GLC GLC GLC GLC BGC 0.488889 0.848485
37 EMZ 0.472222 0.794118
38 BG6 0.461538 0.675
39 BGP 0.461538 0.675
40 G6P 0.461538 0.675
41 M6P 0.461538 0.675
42 M6D 0.461538 0.675
43 A6P 0.461538 0.675
44 GAF 0.457143 0.875
45 SHG 0.457143 0.875
46 2FG 0.457143 0.875
47 G2F 0.457143 0.875
48 2H5 0.457143 0.875
49 GCS 0.457143 0.777778
50 1GN 0.457143 0.777778
51 X6X 0.457143 0.777778
52 PA1 0.457143 0.777778
53 95Z 0.457143 0.777778
54 G3F 0.457143 0.875
55 NGR 0.454545 0.848485
56 MAL 0.454545 0.848485
57 MAN GLC 0.454545 0.848485
58 GAL BGC 0.454545 0.848485
59 GLA GLA 0.454545 0.848485
60 BGC BMA 0.454545 0.848485
61 M3M 0.454545 0.848485
62 GLA GAL 0.454545 0.848485
63 MAB 0.454545 0.848485
64 GLC GAL 0.454545 0.848485
65 B2G 0.454545 0.848485
66 LBT 0.454545 0.848485
67 BMA GAL 0.454545 0.848485
68 LAT 0.454545 0.848485
69 BGC GAL 0.454545 0.848485
70 CBI 0.454545 0.848485
71 CBK 0.454545 0.848485
72 N9S 0.454545 0.848485
73 LB2 0.454545 0.848485
74 3MG 0.444444 0.875
75 TCB 0.444444 0.8
76 GLC SGC 0.444444 0.8
77 YIO 0.441176 0.870968
78 2GS 0.432432 0.875
79 2M4 0.431818 0.848485
80 AHR AHR 0.428571 0.764706
81 GLF 0.428571 0.84375
82 FUB AHR 0.428571 0.764706
83 MAN BMA BMA 0.416667 0.848485
84 BMA MAN BMA 0.416667 0.848485
85 CTR 0.416667 0.848485
86 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.416667 0.848485
87 GLA GAL BGC 0.416667 0.848485
88 CE5 0.416667 0.848485
89 MLR 0.416667 0.848485
90 CE6 0.416667 0.848485
91 MT7 0.416667 0.848485
92 BMA BMA BMA 0.416667 0.848485
93 GLC BGC BGC BGC BGC 0.416667 0.848485
94 MAN MAN BMA BMA BMA BMA 0.416667 0.848485
95 BGC BGC BGC BGC BGC 0.416667 0.848485
96 BGC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
97 BGC GLC GLC 0.416667 0.848485
98 BMA BMA BMA BMA BMA 0.416667 0.848485
99 MAN BMA BMA BMA BMA 0.416667 0.848485
100 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
101 GLC BGC BGC BGC BGC BGC 0.416667 0.848485
102 MAN BMA BMA BMA BMA BMA 0.416667 0.848485
103 BGC BGC BGC BGC BGC BGC 0.416667 0.848485
104 BGC GLC GLC GLC 0.416667 0.848485
105 BGC BGC BGC GLC 0.416667 0.848485
106 CTT 0.416667 0.848485
107 GLA GAL GLC 0.416667 0.848485
108 MTT 0.416667 0.848485
109 GLC BGC BGC BGC 0.416667 0.848485
110 GLC GLC BGC 0.416667 0.848485
111 CEY 0.416667 0.848485
112 B4G 0.416667 0.848485
113 CE8 0.416667 0.848485
114 BMA BMA BMA BMA BMA BMA 0.416667 0.848485
115 GAL FUC 0.416667 0.848485
116 DXI 0.416667 0.848485
117 GLC BGC GLC 0.416667 0.848485
118 CT3 0.416667 0.848485
119 GAL GAL GAL 0.416667 0.848485
120 GLC GLC GLC GLC GLC 0.416667 0.848485
121 BGC BGC BGC BGC 0.416667 0.848485
122 BGC BGC BGC 0.416667 0.848485
123 BGC BGC GLC 0.416667 0.848485
124 CEX 0.416667 0.848485
125 GLC GAL GAL 0.416667 0.848485
126 BGC GLC GLC GLC GLC 0.416667 0.848485
127 GLC BGC BGC 0.416667 0.848485
128 GS1 GLC GS1 0.408163 0.8
129 SGC SGC BGC 0.408163 0.8
130 BGC BGC BGC GLC BGC BGC 0.408163 0.848485
131 GLC BGC BGC BGC BGC BGC BGC 0.408163 0.848485
132 1LL 0.405405 0.771429
133 TDG 0.405405 0.771429
134 TRE 0.405405 0.848485
135 NDG 0.404762 0.7
136 NGA 0.404762 0.7
137 NAG 0.404762 0.7
138 HSQ 0.404762 0.7
139 A2G 0.404762 0.7
140 BM3 0.404762 0.7
141 FUB AHR AHR 0.4 0.764706
142 AHR AHR AHR AHR AHR AHR 0.4 0.764706
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4D52; Ligand: GXL; Similar sites found with APoc: 132
This union binding pocket(no: 1) in the query (biounit: 4d52.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 4LZJ 22H 0.990099
2 4CYI ATP 1.5873
3 1JXZ BCA 1.85874
4 3WQQ IB3 1.90476
5 3WQQ NDP 1.90476
6 1VHD NAP 1.90476
7 1XG4 ICT 2.0339
8 1D6H COA 2.22222
9 1S16 ANP 2.22222
10 1QM5 GLC GLC GLC PO4 SGC GLC 2.22222
11 1E3W NAD 2.29885
12 3VZS NAP 2.33463
13 2Q2V NAD 2.35294
14 1DEK DGP 2.48963
15 3HDY FAD 2.53968
16 3HDY GDU 2.53968
17 3EWC MCF 2.53968
18 4MXP DB4 2.53968
19 4U44 3D9 2.53968
20 5AX9 4KT 2.5974
21 5GP0 GPP 2.68456
22 4RPO T6C 2.69058
23 3K7S R52 2.7933
24 3GC8 B45 2.85714
25 4OOE FOM 2.85714
26 6H3O FAD 2.85714
27 1ZBQ NAD 2.85714
28 2HZQ STR 2.87356
29 5WQP NCA 2.99145
30 4C1K PEP 3.05344
31 5OX6 A1Z 3.1746
32 5L9B AKG 3.1746
33 5L9V OGA 3.1746
34 1V8B NAD 3.1746
35 5BO9 SIA GAL NGS 3.1746
36 3KRL KRL 3.1746
37 4IE6 UN9 3.1746
38 1IYK MIM 3.1746
39 4D9C PMP 3.1746
40 3HQR OGA 3.25203
41 6A0S HSE 3.31325
42 6A0S NDP 3.31325
43 3A28 NAD 3.48837
44 4MIG G3F 3.49206
45 4Y1B NAP 3.49206
46 1OYB HBA 3.49206
47 1OYB FMN 3.49206
48 1GEG NAD 3.51562
49 3AI8 HNQ 3.51562
50 5ZFJ 9BF 3.52423
51 5EJ2 NAD 3.57143
52 1XG5 NAP 3.58423
53 4NBU NAI 3.6
54 1PR9 NAP 3.68852
55 1GT6 OLA 3.71747
56 5TDF 7A3 3.80952
57 6EL3 NAP 3.80952
58 4Q5M ROC 3.94089
59 4X7Y SAH 4.0146
60 3T3C 017 4.0404
61 5T2Z 017 4.0404
62 1JQ3 AAT 4.05405
63 4NDO ATP 4.07407
64 4RVG TYD 4.12698
65 1REQ DCA 4.12698
66 5JWC FAD 4.12698
67 1WM1 PTB 4.12698
68 5OHJ 9VE 4.12698
69 2XIQ MLC 4.12698
70 4XCB AKG 4.21456
71 1ZPD DPX 4.22535
72 1G0N NDP 4.24028
73 1G0N PHH 4.24028
74 3LL5 IPE 4.41767
75 3LL5 ADP 4.41767
76 3A2Q ACA ACA 4.44444
77 2WKQ FMN 4.44444
78 2BES RES 4.65116
79 3QWB NDP 4.7619
80 3KA2 2NC 4.92611
81 3FSM 2NC 4.92611
82 4IP7 FLC 5.07937
83 4EUU BX7 5.07937
84 3WXL ADP 5.07937
85 4J25 OGA 5.24017
86 4XB2 NDP 5.39683
87 4XB2 HSE 5.39683
88 1W2T SUC GLA 5.39683
89 4XF6 ADP 5.49451
90 4XF6 LIP 5.49451
91 4XF6 INS 5.49451
92 2HU5 GLY PHE 5.71429
93 2TPS TPS 5.72687
94 3U3U EAH 6.00858
95 4ELG 52I 6.0241
96 1C3R TSN 6.03175
97 4KCT PYR 6.03175
98 2JC9 ADN 6.03175
99 3A06 FOM 6.34921
100 4UXL 5P8 6.66667
101 4HI0 GDP 6.69291
102 5GWT NAD 6.83453
103 5WO4 B7V 6.95364
104 5V2J UDP 6.98413
105 5V2J 7WV 6.98413
106 1Q0H NDP 6.98413
107 6BFN DL1 7.01754
108 4RT1 C2E 7.14286
109 3PIJ FRU 7.30159
110 4Y85 499 7.30159
111 4A4X JUP 7.52688
112 5LNQ CAA 7.61905
113 1XKQ NDP 7.85714
114 3RUU 37G 7.86026
115 3GNE FLC 7.93651
116 2FXD DR7 8.08081
117 3S43 478 8.08081
118 4NJS G08 8.08081
119 3A6T 8OG 8.52713
120 1XOC VAL ASP SER LYS ASN THR SER SER TRP 8.57143
121 1Y9G FRU 8.57143
122 1FLM FMN 9.01639
123 2O07 MTA 9.21053
124 2O07 SPD 9.21053
125 4IX4 ADP 9.52381
126 2OFV 242 10.1083
127 1WCB PE1 11.2676
128 1F0X FAD 12.0635
129 1BAI 0Q4 13.7097
130 3AFN NAP 14.7287
131 1I7M CG 16.4794
132 2OMN IPH 19.3548
Pocket No.: 2; Query (leader) PDB : 4D52; Ligand: GXL; Similar sites found with APoc: 131
This union binding pocket(no: 2) in the query (biounit: 4d52.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 1FK5 OLA None
2 1Z2P I3S 1.26984
3 1Z2P ACP 1.26984
4 4EN4 GT1 1.60256
5 4EN4 ATP 1.60256
6 4EN4 GT0 1.60256
7 2DHC DCE 1.6129
8 1HZP DAO 1.90476
9 5XWC 8GL 1.90476
10 5XWC 2IT 1.90476
11 5XWC NAP 1.90476
12 5ML3 DL3 2.01342
13 2R5V HHH 2.22222
14 2Q7D ANP 2.22222
15 3ALN ANP 2.22222
16 1VA6 ADP 2.22222
17 4B4D FAD 2.29008
18 6CI9 NAP 2.3166
19 5N0L ILE 2.51572
20 2C6Q NDP 2.53968
21 2C6Q IMP 2.53968
22 4NZN 2OU 2.53968
23 4NZN ANP 2.53968
24 3PGU OLA 2.53968
25 4EWH T77 2.54545
26 1J3R 6PG 2.63158
27 4JGP PYR 2.76498
28 1X0P FAD 2.7972
29 5K21 6QF 2.83688
30 5VZ0 ADP 2.85714
31 5U98 1KX 3.0303
32 6EXF LYS 3.1746
33 4CLI 5P8 3.1746
34 2PZI AXX 3.1746
35 3NUG NAD 3.23887
36 1QIN GIP 3.27869
37 2NVA PL2 3.49206
38 4WNK 453 3.49206
39 2PVN P63 3.49206
40 4OCV ANP 3.49206
41 1SDW IYT 3.50318
42 4FE2 AIR 3.52941
43 5HV0 AKG 3.68664
44 1PVN MZP 3.7234
45 3ORK AGS 3.85852
46 1NE6 SP1 3.88693
47 3RGA ILD 3.88693
48 3FW4 CAQ 3.93258
49 1UMZ BGC BGC XYS BGC XYS GAL 3.95683
50 2JIG PD2 4.01786
51 5NBW 8SK 4.05405
52 3LXK MI1 4.12698
53 2JLD AG1 4.12698
54 5E4R NAP 4.12698
55 5FKP 6UL 4.21053
56 2JEN GLC GLC BGC XYS BGC XYS 4.21456
57 2G5C NAD 4.27046
58 5IXH OTP 4.34783
59 4NG2 OHN 4.42478
60 2OBD 2OB 4.44444
61 5X1M DHB 4.44444
62 5I8T LAC 4.46927
63 5N87 N66 4.47284
64 2GQS C2R 4.64135
65 3T50 FMN 4.6875
66 4ZU4 4TG 4.72973
67 1OIK AKG 4.98339
68 1OIK C26 4.98339
69 3OGV PTQ 5.07937
70 1I1N SAH 5.30973
71 5KJZ PCG 5.33333
72 3KDM TES 5.33333
73 1EWF PC1 5.39683
74 5KR7 6X9 5.39683
75 4JD3 PLM 5.39683
76 4JD3 COA 5.39683
77 2I6A 5I5 5.39683
78 5E70 RCD 5.39683
79 3LVW GSH 5.39683
80 1LFO OLA 5.46875
81 4P25 FUC GAL NAG FUC 5.62914
82 3RI1 3RH 5.7508
83 1S20 NAD 5.88235
84 1XTP SAI 5.90551
85 1OS7 TAU 6.00707
86 1OS7 AKG 6.00707
87 2OJW ADP 6.03175
88 2X41 BGC 6.03175
89 3VPD ANP 6.04982
90 5NIU 8YZ 6.25
91 5JU6 BGC 6.34921
92 1ELU CSS 6.34921
93 1ELU PDA 6.34921
94 3OF1 CMP 6.50407
95 4B1L FRU 6.66667
96 4C5N ACP 6.88406
97 4RLT FSE 6.96203
98 4ITM ATP 6.98413
99 4QCK ASD 6.98413
100 5IXG OTP 7.10059
101 3PNA CMP 7.14286
102 5LXT ACP 7.61905
103 3ZL8 ADP 7.61905
104 6BU0 IHP 7.63359
105 2Z77 HE7 7.91367
106 1QVJ RP5 8.21918
107 1H8S AIC 8.33333
108 5IQT AKG 8.57143
109 5IQT 6CU 8.57143
110 1IIU RTL 9.1954
111 5EVY SAL 9.52381
112 2XN2 GLA 9.52381
113 3QUZ QUV 9.54357
114 4WN5 MVC 9.56522
115 1N5S ADL 9.82143
116 3EKK GS2 10.0977
117 4F7E 0SH 10.2041
118 3STD MQ0 10.9091
119 1EWJ BLM 11.1111
120 4CCN OGA 11.4286
121 3ZO7 K6H 11.7021
122 3RUG DB6 11.7647
123 4K3H 1OM 11.8644
124 5KY3 GFB 12.5
125 5DRB 5FJ 13.4021
126 2YFO GLA 13.6508
127 2YFO GAL 13.6508
128 4TW7 37K 14.0625
129 1MFD GLA MMA ABE 14.8837
130 2E1A MSE 18.6667
131 3VPB ADP 25
Pocket No.: 3; Query (leader) PDB : 4D52; Ligand: GXL; Similar sites found with APoc: 83
This union binding pocket(no: 3) in the query (biounit: 4d52.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 3G5D 1N1 1.3986
2 2BJF DXC 1.5873
3 1CX4 CMP 1.63934
4 5VC5 96M 1.7301
5 4Y9J UCC 1.90476
6 4Y9J FAD 1.90476
7 1T7Q COA 2.22222
8 1T7Q 152 2.22222
9 2YNE NHW 2.22222
10 2YNE YNE 2.22222
11 3UN3 G16 2.22222
12 2RDQ AKG 2.43056
13 3KDU NKS 2.52708
14 3BZ3 YAM 2.53623
15 1DRY AKG 2.53968
16 1DRY AAG 2.53968
17 2WU6 DKI 2.53968
18 4X6X S74 2.53968
19 5XPL 8C9 2.58303
20 2GC0 PAN 2.65957
21 4IZY 1J2 2.85714
22 2ET1 GLV 2.98507
23 1O4T OXL 3.00752
24 3AJH BL3 3.22581
25 4Z87 GDP 3.49206
26 4L80 1VU 3.49206
27 3LKJ LKJ 3.5461
28 3HXG GTA 3.7037
29 5OCG 9R5 3.7037
30 5TDF ADP 3.80952
31 3PQB VGP 3.80952
32 6FA4 D1W 4.04624
33 5KWY C3S 4.04858
34 5HGR 45D 4.12698
35 5OMY 9YE 4.12698
36 1SQ5 PAU 4.22078
37 3HMO STU 4.44444
38 3G4G D71 4.44444
39 1UU6 BGC BGC BGC BGC 4.46429
40 3P2H NOO 4.47761
41 4R78 AMP 4.53074
42 3A76 SPD 4.54545
43 2PR5 FMN 4.54545
44 4KU7 PCG 4.57516
45 5Y9D FAD 4.7619
46 5TO8 7FM 4.96454
47 5DQ8 FLF 5
48 1SO0 GAL 5.07937
49 5EH0 5NW 5.42636
50 5GM5 CBI 5.45455
51 3TAY MN0 5.52147
52 4RLQ 3SK 5.71429
53 5ZYN FAD 5.71429
54 1ZP9 ATP 5.81395
55 4B1M FRU FRU 5.94595
56 3A7R LAQ 6.34921
57 5C2H 4XU 6.34921
58 1DQX BMP 6.36704
59 2BWA GLC BGC 6.60793
60 3PG7 PTY 6.64062
61 1MJJ HAL 6.84932
62 4YHO 4CC 6.84932
63 4BVA T3 6.98413
64 4MDH NAD 7.61905
65 4OFG PCG 7.63889
66 5H41 IFM 7.93651
67 2BPM 529 8.09062
68 3E85 BSU 8.22785
69 5FPX GLY SER SER HIS HIS HIS HIS HIS 8.84956
70 5AMH EF2 9.6
71 5FLJ QUE 9.67742
72 1XNK XS2 9.69388
73 3QXV MTX 10.3175
74 5V7P SAH 11.5789
75 1XW6 GSH 11.9266
76 5WCZ NOJ 12.0635
77 2WSA 646 12.381
78 2WSA MYA 12.381
79 5BV6 35G 13.1579
80 2CM4 RCL 14.6667
81 5VM6 9EG 16.7883
82 2QQC AG2 30.1887
83 1N13 AG2 30.7692
Pocket No.: 4; Query (leader) PDB : 4D52; Ligand: GIV; Similar sites found with APoc: 111
This union binding pocket(no: 4) in the query (biounit: 4d52.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 3G5D 1N1 1.3986
2 2BJF DXC 1.5873
3 1CX4 CMP 1.63934
4 5VC5 96M 1.7301
5 1HZP DAO 1.90476
6 4Y9J UCC 1.90476
7 4Y9J FAD 1.90476
8 1T7Q COA 2.22222
9 1T7Q 152 2.22222
10 2YNE YNE 2.22222
11 2YNE NHW 2.22222
12 2Q7D ANP 2.22222
13 3UN3 G16 2.22222
14 2RDQ AKG 2.43056
15 3KDU NKS 2.52708
16 3BZ3 YAM 2.53623
17 1DRY AAG 2.53968
18 1DRY AKG 2.53968
19 2WU6 DKI 2.53968
20 4X6X S74 2.53968
21 5XPL 8C9 2.58303
22 1J3R 6PG 2.63158
23 2GC0 PAN 2.65957
24 5K21 6QF 2.83688
25 4IZY 1J2 2.85714
26 2HZQ STR 2.87356
27 2ET1 GLV 2.98507
28 1O4T OXL 3.00752
29 5L9B AKG 3.1746
30 5L9V OGA 3.1746
31 3AJH BL3 3.22581
32 1QIN GIP 3.27869
33 4Z87 GDP 3.49206
34 4L80 1VU 3.49206
35 3LKJ LKJ 3.5461
36 3HXG GTA 3.7037
37 5OCG 9R5 3.7037
38 5TDF ADP 3.80952
39 3PQB VGP 3.80952
40 1NE6 SP1 3.88693
41 2JIG PD2 4.01786
42 6FA4 D1W 4.04624
43 5KWY C3S 4.04858
44 5NBW 8SK 4.05405
45 2XIQ MLC 4.12698
46 5HGR 45D 4.12698
47 5OMY 9YE 4.12698
48 1SQ5 PAU 4.22078
49 2OBD 2OB 4.44444
50 3HMO STU 4.44444
51 3G4G D71 4.44444
52 1UU6 BGC BGC BGC BGC 4.46429
53 5N87 N66 4.47284
54 3P2H NOO 4.47761
55 4R78 AMP 4.53074
56 3A76 SPD 4.54545
57 2PR5 FMN 4.54545
58 4KU7 PCG 4.57516
59 4ZU4 4TG 4.72973
60 5Y9D FAD 4.7619
61 5TO8 7FM 4.96454
62 5DQ8 FLF 5
63 1SO0 GAL 5.07937
64 4J25 OGA 5.24017
65 5KJZ PCG 5.33333
66 5EH0 5NW 5.42636
67 5GM5 CBI 5.45455
68 3TAY MN0 5.52147
69 4RLQ 3SK 5.71429
70 5ZYN FAD 5.71429
71 1ZP9 ATP 5.81395
72 4B1M FRU FRU 5.94595
73 5NIU 8YZ 6.25
74 3A7R LAQ 6.34921
75 5C2H 4XU 6.34921
76 1DQX BMP 6.36704
77 2BWA GLC BGC 6.60793
78 3PG7 PTY 6.64062
79 1MJJ HAL 6.84932
80 4YHO 4CC 6.84932
81 4BVA T3 6.98413
82 5IXG OTP 7.10059
83 3PNA CMP 7.14286
84 4MDH NAD 7.61905
85 6BU0 IHP 7.63359
86 4OFG PCG 7.63889
87 2Z77 HE7 7.91367
88 5H41 IFM 7.93651
89 2BPM 529 8.09062
90 3E85 BSU 8.22785
91 5FPX GLY SER SER HIS HIS HIS HIS HIS 8.84956
92 1IIU RTL 9.1954
93 5AMH EF2 9.6
94 5FLJ QUE 9.67742
95 1XNK XS2 9.69388
96 1N5S ADL 9.82143
97 3EKK GS2 10.0977
98 3QXV MTX 10.3175
99 1EWJ BLM 11.1111
100 5V7P SAH 11.5789
101 1XW6 GSH 11.9266
102 5WCZ NOJ 12.0635
103 2WSA 646 12.381
104 2WSA MYA 12.381
105 5BV6 35G 13.1579
106 5DRB 5FJ 13.4021
107 4TW7 37K 14.0625
108 2CM4 RCL 14.6667
109 5VM6 9EG 16.7883
110 2QQC AG2 30.1887
111 1N13 AG2 30.7692
Pocket No.: 5; Query (leader) PDB : 4D52; Ligand: GXL; Similar sites found with APoc: 64
This union binding pocket(no: 5) in the query (biounit: 4d52.bio1) has 9 residues
No: Leader PDB Ligand Sequence Similarity
1 6BFG FMN 0.952381
2 4AVV CD 2.45098
3 3C3Y SAH 2.53165
4 5HCA BGC 2.55474
5 6CZI 38E 2.67857
6 2GWH PCI 2.68456
7 4BFM ANP 2.85714
8 1QRP HH0 2.85714
9 4P5Z Q7M 2.85714
10 2YCJ C2F 2.95203
11 3SCH TB6 3.0303
12 1ZZ7 S0H 3.0303
13 5E2N V14 3.04183
14 2E7F C2F 3.05344
15 4CW5 FMN 3.1746
16 5LAU AR6 3.36538
17 4O1F THG 3.44828
18 5JSD 1GN ACY GAL ACY 1GN BGC GAL BGC 3.49206
19 5JSD ACY 1GN GAL 1GN BGC ACY GAL BGC 3.49206
20 5IH9 6BF 3.58209
21 5MJA 7O3 3.93443
22 4P7X YCP 4.10959
23 4P7X AKG 4.10959
24 1BZL GCG 4.12698
25 2WBP ZZU 4.18994
26 2WBP SIN 4.18994
27 5Z75 NAD 4.28135
28 4WOV 3SM 4.44444
29 2ZXI FAD 4.7619
30 3RM4 3RM 4.7619
31 4LJ9 ACP 4.7619
32 2BNJ XYP XYP AHR FER 4.9505
33 5JZJ AN2 5.05051
34 4H6Q TFB 5.12821
35 4LA7 A1O 5.18135
36 1VQ2 DDN 5.18135
37 5KO1 6UY 5.65371
38 3D91 REM 5.71429
39 2J9C ATP 5.88235
40 2OG7 SIN 6.03175
41 5LI9 ACP 6.03175
42 1J0D 5PA 6.03175
43 1EB1 ASP TYR GLU PRO ILE PRO GLU GLU ALA PHE 6.22568
44 3OCP CMP 6.47482
45 3UDZ ADP 6.98413
46 3QP8 HL0 7.06522
47 3GLC R5P 7.11864
48 4WVO 3UZ 7.18232
49 1Q6O LG6 7.87037
50 2Z77 NCA 7.91367
51 4GID 0GH 7.93651
52 2J9D ADP 8.40336
53 1U7Z PMT 8.40708
54 2GJ5 VD3 8.64198
55 5EZU MYR 8.98876
56 3THR C2F 9.21502
57 4M26 AKG 10.1587
58 2BFR ADP 10.4167
59 4HWT 1B2 10.4762
60 1W2D ADP 11.6981
61 4WW7 AMP 12.2995
62 6C4A PYR 13.0159
63 3FN0 TRP ASN TRP PHE ASP ILE THR ASN LYS 16.8831
64 3DZ6 PUT 17.2285
Pocket No.: 6; Query (leader) PDB : 4D52; Ligand: GIV; Similar sites found with APoc: 117
This union binding pocket(no: 6) in the query (biounit: 4d52.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 1FK5 OLA None
2 1Z2P I3S 1.26984
3 1Z2P ACP 1.26984
4 4EN4 GT1 1.60256
5 4EN4 GT0 1.60256
6 4EN4 ATP 1.60256
7 2DHC DCE 1.6129
8 5XWC 2IT 1.90476
9 5XWC 8GL 1.90476
10 5XWC NAP 1.90476
11 5ML3 DL3 2.01342
12 1XG4 ICT 2.0339
13 2R5V HHH 2.22222
14 3ALN ANP 2.22222
15 1VA6 ADP 2.22222
16 4B4D FAD 2.29008
17 6CI9 NAP 2.3166
18 5N0L ILE 2.51572
19 2C6Q NDP 2.53968
20 2C6Q IMP 2.53968
21 4NZN ANP 2.53968
22 4NZN 2OU 2.53968
23 3PGU OLA 2.53968
24 4EWH T77 2.54545
25 4RPO T6C 2.69058
26 4JGP PYR 2.76498
27 1X0P FAD 2.7972
28 5VZ0 ADP 2.85714
29 5U98 1KX 3.0303
30 6EXF LYS 3.1746
31 4CLI 5P8 3.1746
32 5OX6 A1Z 3.1746
33 2PZI AXX 3.1746
34 3NUG NAD 3.23887
35 2NVA PL2 3.49206
36 4WNK 453 3.49206
37 2PVN P63 3.49206
38 4OCV ANP 3.49206
39 1SDW IYT 3.50318
40 4FE2 AIR 3.52941
41 5HV0 AKG 3.68664
42 1PVN MZP 3.7234
43 3ORK AGS 3.85852
44 3RGA ILD 3.88693
45 3FW4 CAQ 3.93258
46 1UMZ BGC BGC XYS BGC XYS GAL 3.95683
47 3LXK MI1 4.12698
48 1REQ DCA 4.12698
49 2JLD AG1 4.12698
50 5E4R NAP 4.12698
51 5FKP 6UL 4.21053
52 2JEN GLC GLC BGC XYS BGC XYS 4.21456
53 2G5C NAD 4.27046
54 5IXH OTP 4.34783
55 4NG2 OHN 4.42478
56 5X1M DHB 4.44444
57 5I8T LAC 4.46927
58 2GQS C2R 4.64135
59 3T50 FMN 4.6875
60 1OIK C26 4.98339
61 1OIK AKG 4.98339
62 3OGV PTQ 5.07937
63 4EUU BX7 5.07937
64 1I1N SAH 5.30973
65 3KDM TES 5.33333
66 1EWF PC1 5.39683
67 5KR7 6X9 5.39683
68 4JD3 PLM 5.39683
69 4JD3 COA 5.39683
70 2I6A 5I5 5.39683
71 5E70 RCD 5.39683
72 3LVW GSH 5.39683
73 1LFO OLA 5.46875
74 4P25 FUC GAL NAG FUC 5.62914
75 2TPS TPS 5.72687
76 3RI1 3RH 5.7508
77 1S20 NAD 5.88235
78 1XTP SAI 5.90551
79 1OS7 TAU 6.00707
80 1OS7 AKG 6.00707
81 2OJW ADP 6.03175
82 2X41 BGC 6.03175
83 3VPD ANP 6.04982
84 5JU6 BGC 6.34921
85 1ELU PDA 6.34921
86 1ELU CSS 6.34921
87 3OF1 CMP 6.50407
88 4B1L FRU 6.66667
89 4UXL 5P8 6.66667
90 4C5N ACP 6.88406
91 5WO4 B7V 6.95364
92 4RLT FSE 6.96203
93 4ITM ATP 6.98413
94 4QCK ASD 6.98413
95 5LXT ACP 7.61905
96 3ZL8 ADP 7.61905
97 1QVJ RP5 8.21918
98 1H8S AIC 8.33333
99 3A6T 8OG 8.52713
100 5IQT AKG 8.57143
101 5IQT 6CU 8.57143
102 5EVY SAL 9.52381
103 2XN2 GLA 9.52381
104 3QUZ QUV 9.54357
105 4WN5 MVC 9.56522
106 4F7E 0SH 10.2041
107 3STD MQ0 10.9091
108 4CCN OGA 11.4286
109 3ZO7 K6H 11.7021
110 3RUG DB6 11.7647
111 4K3H 1OM 11.8644
112 5KY3 GFB 12.5
113 2YFO GAL 13.6508
114 2YFO GLA 13.6508
115 1MFD GLA MMA ABE 14.8837
116 2E1A MSE 18.6667
117 3VPB ADP 25
Pocket No.: 7; Query (leader) PDB : 4D52; Ligand: GIV; Similar sites found with APoc: 102
This union binding pocket(no: 7) in the query (biounit: 4d52.bio1) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 2YJ0 420 None
2 5A6N U7E 1.06007
3 3B1Q NOS 1.5873
4 3GC0 AMP 1.5873
5 3ZBQ GDP 1.5873
6 3TM0 ANP 1.90114
7 3TM0 B31 1.90114
8 5UL5 PLM 1.90476
9 5UL5 8D7 1.90476
10 3PTG 932 2.22222
11 2WA4 069 2.22222
12 4B7E OGA 2.22222
13 5YBN AKG 2.2293
14 4Q0P 0MK 2.30769
15 4AVV GHE 2.45098
16 4AVV CD 2.45098
17 2CDC XYP 2.53968
18 4CS4 AXZ 2.55474
19 5HCA BGC 2.55474
20 5F2T PLM 2.5974
21 6CZI 38E 2.67857
22 2GWH PCI 2.68456
23 1AKY AP5 2.72727
24 3GC8 B45 2.85714
25 4TM3 FAD 2.85714
26 4BFM ANP 2.85714
27 1QRP HH0 2.85714
28 4C2X NHW 2.85714
29 1LLO NAA NAA AMI 2.9304
30 3SCH TB6 3.0303
31 5E2N V14 3.04183
32 4CW5 FMN 3.1746
33 2ZQ0 ACR 3.1746
34 5LAU AR6 3.36538
35 1LGT BP3 3.367
36 3U2U UDP 3.42205
37 4WUP 3UF 3.46154
38 3UXL CFI 3.49206
39 2ZE9 PD7 3.49206
40 5JSD 1GN ACY GAL ACY 1GN BGC GAL BGC 3.49206
41 5JSD ACY 1GN GAL 1GN BGC ACY GAL BGC 3.49206
42 4OCT AKG 3.6036
43 3NNF AKG 3.80952
44 4USI ATP 3.8961
45 3FVQ ATP 3.89972
46 1BZL GCG 4.12698
47 2G50 PYR 4.12698
48 4QDF 30Q 4.12698
49 4WOV 3SM 4.44444
50 2GVJ DGB 4.44444
51 2YG2 S1P 4.65116
52 1C7O PPG 4.7619
53 4S3F 43W 4.7619
54 3NEM AMO 4.7619
55 3RM4 3RM 4.7619
56 4GYI ADP 4.78589
57 2AG4 LP3 4.87805
58 2AG4 OLA 4.87805
59 2ARC ARA 4.87805
60 2BNJ XYP XYP AHR FER 4.9505
61 3NCQ ATP 5.04202
62 5JZJ AN2 5.05051
63 4IP7 FLC 5.07937
64 4NMC FAD 5.07937
65 4NMC 2OP 5.07937
66 5HCY 60D 5.07937
67 4OJ8 AKG 5.11945
68 5VCV 1N1 5.14469
69 4LA7 A1O 5.18135
70 1VQ2 DDN 5.18135
71 2HFN FMN 5.22876
72 4B52 RDF 5.26316
73 1NX4 AKG 5.49451
74 4XF6 LIP 5.49451
75 4XF6 INS 5.49451
76 1ECM TSA 5.50459
77 5TBM 79A 5.98291
78 3N0Y APC 6.14525
79 1EB1 ASP TYR GLU PRO ILE PRO GLU GLU ALA PHE 6.22568
80 1RM0 D6P 6.66667
81 1RM0 NAI 6.66667
82 3QP8 HL0 7.06522
83 3GLC R5P 7.11864
84 1NWW HPN 7.38255
85 2DIO EOD 7.44681
86 2Z77 NCA 7.91367
87 2V1O COA 7.94702
88 1I7A PHE 8.10811
89 2J9D ADP 8.40336
90 1U7Z PMT 8.40708
91 1OW4 2AN 8.52713
92 5HA0 LTD 9.61539
93 4M26 AKG 10.1587
94 4M26 SIN 10.1587
95 4M26 ZZU 10.1587
96 1M5W DXP 11.1111
97 1W2D 4IP 11.6981
98 1W2D ADP 11.6981
99 4MVK ACE VAL PHE PHE ALA GLU ASP NH2 14.8936
100 6F4T OGA 14.902
101 5KEW 6SB 15.2778
102 1LYB IVA VAL VAL STA ALA STA 19.5876
103 4UX9 ANP 50
Pocket No.: 8; Query (leader) PDB : 4D52; Ligand: GXL; Similar sites found with APoc: 98
This union binding pocket(no: 8) in the query (biounit: 4d52.bio4) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 2UX9 FMN None
2 5A6N U7E 1.06007
3 2V58 LZJ 1.5873
4 1ZB6 GST 1.62866
5 1ZB6 DIN 1.62866
6 4I94 ANP 1.66667
7 2XK9 XK9 1.90476
8 5FXD H7Y 1.90476
9 5UL5 PLM 1.90476
10 5UL5 8D7 1.90476
11 4J7Q B7N 1.90476
12 3CXO 3LR 1.90476
13 2AQX ATP 2.07612
14 6MPT C30 2.0979
15 2A1L PCW 2.22222
16 2WA4 069 2.22222
17 4WHZ 3NL 2.22222
18 1VA6 P2S 2.22222
19 5JSJ 6PD 2.25225
20 3B50 SLB 2.25806
21 1IM8 SAI 2.45902
22 4RFR RHN 2.46305
23 5EQY 5RA 2.53968
24 5AE9 OKO 2.53968
25 5Y72 DST 2.53968
26 4HIA FMN 2.84091
27 3VHE 42Q 2.85714
28 6EZ6 C5Z 2.85714
29 4OTH DRN 2.93255
30 4RFM 3P6 3.00752
31 5LIA 6XN 3.1746
32 4UWJ 7L5 3.1746
33 4UWJ MYA 3.1746
34 5LRT ADP 3.1746
35 5VJE GOS 3.1746
36 6EOZ AKG 3.24675
37 6EOZ 58K 3.24675
38 4WUP 3UF 3.46154
39 5W19 9TD 3.49206
40 3VEH 0GA 3.49206
41 3NW7 LGV 3.58306
42 2QK4 ATP 3.80952
43 3F5K CE5 3.80952
44 2F59 INI 3.82166
45 1KHZ ADV 3.82775
46 3RGA LSB 3.88693
47 5JSP DQY 3.9801
48 4YDQ HFG 4.44444
49 4YDQ ANP 4.44444
50 5TA6 79D 4.44444
51 2GVJ DGB 4.44444
52 3PUR 2HG 4.44444
53 6D61 4AA 4.61538
54 5YS9 FAD 4.7619
55 1I82 BGC BGC 4.7619
56 2EG7 OTD 4.7619
57 3QP6 HL6 4.90566
58 3NCQ ATP 5.04202
59 1V97 FAD 5.07937
60 4OJ8 2TQ 5.11945
61 1QY1 PRZ 5.39683
62 5H5A 6OU 5.41667
63 1NX4 AKG 5.49451
64 3VQ2 LP4 LP5 MYR DAO 5.55556
65 4HVA 4HV 5.66038
66 5WP4 PC 5.71429
67 1OPB RET 5.97015
68 5EW0 3C7 5.98291
69 4P42 PEE 6.03175
70 5LI1 ANP 6.03175
71 3N0Y APC 6.14525
72 3M3E GAL A2G NPO 6.21118
73 1SQI 869 6.34921
74 1RM0 D6P 6.66667
75 5MW8 ATP 6.66667
76 1OLM VTQ 6.98413
77 5UR6 8KM 7.18232
78 4WW8 VD9 7.22433
79 4RW3 IPD 7.28477
80 5UKL SIX 7.30159
81 4OMJ 2TX 7.91367
82 5H41 BGC GLC 7.93651
83 3VV1 GAL FUC 8.125
84 2XMY CDK 8.38926
85 5XQW 8EU 8.53081
86 3W8X FTK 9.20635
87 3W8X FAD 9.20635
88 4R3U 3KK 9.49367
89 4R3U 3HC 9.49367
90 4M26 SIN 10.1587
91 4M26 ZZU 10.1587
92 2IFW ACE PHE LYS PHE PSA LEU AAR 11.165
93 1ERB ETR 11.4754
94 5IF4 6AK 12.5786
95 5DBX ANP 12.6984
96 5VL2 9EG 14.3939
97 1OGX EQU 16.7939
98 4QXB OGA 33.3333
Pocket No.: 9; Query (leader) PDB : 4D52; Ligand: GIV; Similar sites found with APoc: 81
This union binding pocket(no: 9) in the query (biounit: 4d52.bio4) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 1F5F DHT 1.46341
2 4AG8 AXI 1.5873
3 2V58 LZJ 1.5873
4 1ZB6 GST 1.62866
5 1ZB6 DIN 1.62866
6 2XK9 XK9 1.90476
7 4J7Q B7N 1.90476
8 4DI8 0GY 1.9802
9 4DI8 0GZ 1.9802
10 6MPT C30 2.0979
11 6FXR AKG 2.22222
12 5W4W 9WG 2.22222
13 5JSJ 6PD 2.25225
14 3B50 SLB 2.25806
15 1IM8 SAI 2.45902
16 4RFR RHN 2.46305
17 5EQY 5RA 2.53968
18 5Y72 DST 2.53968
19 3Q60 ATP 2.53968
20 5AE9 OKO 2.53968
21 3AMN CBI 2.64151
22 3AMN CBK 2.64151
23 4HIA FMN 2.84091
24 3VHE 42Q 2.85714
25 5NBP BGC BGC BGC 2.94118
26 1ZZ7 S0H 3.0303
27 4MNS 2AX 3.14465
28 3E2M E2M 3.24324
29 4L3L 5FI 3.28947
30 5W19 9TD 3.49206
31 3NW7 LGV 3.58306
32 2F59 INI 3.82166
33 3RGA LSB 3.88693
34 4P7X AKG 4.10959
35 4P7X YCP 4.10959
36 5C3R AKG 4.12698
37 5C3R HMU 4.12698
38 4KBS PX2 4.18605
39 4YDQ HFG 4.44444
40 4YDQ ANP 4.44444
41 5TA6 79D 4.44444
42 6E08 NAP 4.44444
43 2GQS ADP 4.64135
44 4WO4 JLS 4.74453
45 2ZYI STE 4.7619
46 1I82 BGC BGC 4.7619
47 4MLO PAM 5.07246
48 3OZ2 OZ2 5.39683
49 1QY1 PRZ 5.39683
50 5H5A 6OU 5.41667
51 4XF6 ADP 5.49451
52 5NKB 8ZT 5.55556
53 3D91 REM 5.71429
54 2YGN PCF 5.76923
55 5LI9 ACP 6.03175
56 1J0D 5PA 6.03175
57 2OG7 SIN 6.03175
58 3M3E GAL A2G NPO 6.21118
59 2E56 MYR 6.25
60 5NKN LOC 6.32184
61 3IS2 FAD 6.49351
62 3BJK CIT 6.53595
63 3D72 FAD 6.71141
64 6ECG PM9 6.98413
65