Receptor
PDB id Resolution Class Description Source Keywords
4DCT 2.3 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF B. SUBTILIS ENGA IN COMPLEX WITH HALF-O GDP BACILLUS SUBTILIS GTPASE ENGA GDP PROTEIN BINDING HYDROLASE
Ref.: POTASSIUM ACTS AS A GTPASE-ACTIVATING ELEMENT ON EA NUCLEOTIDE-BINDING DOMAIN OF THE ESSENTIAL BACILLUS ENGA. PLOS ONE V. 7 46795 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP A:501;
A:502;
Valid;
Valid;
none;
none;
Kd = 8 uM
443.201 C10 H15 N5 O11 P2 c1nc2...
SO4 A:503;
Invalid;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4DCT 2.3 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF B. SUBTILIS ENGA IN COMPLEX WITH HALF-O GDP BACILLUS SUBTILIS GTPASE ENGA GDP PROTEIN BINDING HYDROLASE
Ref.: POTASSIUM ACTS AS A GTPASE-ACTIVATING ELEMENT ON EA NUCLEOTIDE-BINDING DOMAIN OF THE ESSENTIAL BACILLUS ENGA. PLOS ONE V. 7 46795 2012
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 473 families.
1 2HJG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 4DCT Kd = 8 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 4DCS Kd = 8 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 4DCU Kd = 8 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 355 families.
1 2HJG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 4DCT Kd = 8 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 4DCS Kd = 8 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 4DCU Kd = 8 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 272 families.
1 2HJG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 4DCT Kd = 8 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 4DCS Kd = 8 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 4DCU Kd = 8 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 1MKY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4DCT; Ligand: GDP; Similar sites found: 555
This union binding pocket(no: 1) in the query (biounit: 4dct.bio1) has 17 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3FKQ ATP 0.000005302 0.50889 1.34048
2 5I34 GDP 0.00002116 0.52204 1.36054
3 2VVG ADP 0.000000651 0.49916 1.42857
4 2WHX ADP 0.00002391 0.47155 1.53509
5 2JLR ANP 0.0003065 0.47421 1.55211
6 1SQ5 ADP 0.00003807 0.51036 1.62338
7 1QF5 GDP 0.0002684 0.52161 1.62413
8 1QF5 RPL 0.0394 0.43379 1.62413
9 3BFX A3P 0.001267 0.40543 1.68919
10 3P4X ADP 0.00001703 0.5067 1.69492
11 3ZFD ANP 0.00005284 0.50683 1.7094
12 1NHX FTB 0.001049 0.48603 1.75439
13 2GMV UN8 0.0004231 0.48598 1.75439
14 1NHX PEP 0.001045 0.48505 1.75439
15 2GMV PEP 0.0005792 0.48254 1.75439
16 1OS1 PYR 0.001523 0.46194 1.75439
17 1OS1 ATP 0.00142 0.46194 1.75439
18 1OYY AGS 0.001932 0.42589 1.75439
19 2ZFI ADP 0.00004134 0.51562 1.91257
20 4KBF AMP 0.001411 0.42459 1.91781
21 5I0H ADP BEF 0.0002772 0.4833 1.97368
22 3B7G ANP 0.0001002 0.49112 2.17391
23 2Q2Y MKR 0.0005561 0.49438 2.17984
24 2Q2Y ADP 0.0005875 0.49438 2.17984
25 2BIF ANP 0.0002105 0.50876 2.19298
26 2BIF SIN 0.0003584 0.50876 2.19298
27 4IOK ADP 0.0007723 0.47326 2.19298
28 4IOK XPO 0.0006028 0.47326 2.19298
29 5LTJ ADP 0.0004394 0.46172 2.19298
30 5XDR ADP 0.001013 0.44511 2.19298
31 4YNU FAD 0.03171 0.41164 2.19298
32 1QHG ATP 0.009691 0.40448 2.19298
33 1JQN DCO 0.008033 0.40386 2.19298
34 5LB3 ADP 0.00003188 0.49359 2.24719
35 3EZ2 ADP 0.0002489 0.48537 2.26131
36 1P9B GDP 0.00006098 0.50943 2.26244
37 4AG5 ADP 0.000004983 0.58352 2.29592
38 5VGR GDP 0.00007656 0.463 2.32019
39 2XT3 ADP 0.000001453 0.50465 2.32558
40 1J99 AND 0.02231 0.40807 2.38908
41 5IRN ADP 0.00004468 0.51304 2.41228
42 2FAH GDP 0.0001182 0.49343 2.41228
43 1YTM ATP 0.0002429 0.42952 2.41228
44 3E1T FAD 0.02049 0.42068 2.41228
45 3E70 GDP 0.000003792 0.55622 2.43902
46 1NJR XYL 0.0219 0.40366 2.46479
47 1ION ADP 0.0001238 0.48978 2.46914
48 1AZT GSP 0.00000002958 0.69067 2.48756
49 1HTW ADP 0.00004371 0.50761 2.53165
50 3FWY ADP 0.0000005645 0.60444 2.54777
51 5K5Z ANP 0.0000639 0.52006 2.54777
52 1TQ4 GDP 0.000000005029 0.59797 2.66344
53 1G41 ADP 0.00009162 0.49581 2.7027
54 1NST A3P 0.003999 0.42452 2.76923
55 4OHY ANP 0.00006522 0.42197 2.78422
56 1FNN ADP 0.0001 0.4491 2.82776
57 1OXV ANP 0.00005323 0.48166 2.83286
58 1YQT ADP 0.00002854 0.47038 2.85088
59 1T5C ADP 0.000001854 0.48433 2.86533
60 2AWN ADP 0.0000005702 0.6506 2.88714
61 3QXC ATP 0.00008832 0.41128 2.89256
62 3DC4 ADP 0.00004244 0.47564 2.90698
63 5L3W GDP 0.000002786 0.56577 2.94118
64 2PL3 ADP 0.0001155 0.50145 2.9661
65 2GDJ ANP 0.0004623 0.46637 3.0303
66 1CR1 TTP 0.0001285 0.49908 3.04054
67 4IDN GNP 0.00008537 0.50975 3.07018
68 3TBK ANP 0.0002469 0.44943 3.07018
69 3Q9L ATP 0.0002415 0.44405 3.07692
70 2FNA ADP 0.0000231 0.45329 3.08123
71 5MVR ADP 0.00003308 0.50337 3.08642
72 2WOJ ADP ALF 0.00004556 0.53116 3.10734
73 3ZS9 ADP ALF 0.00004684 0.42029 3.10734
74 1FP6 ADP 0.00001122 0.50725 3.11419
75 1F9V ADP 0.000007085 0.49712 3.17003
76 3COB ADP 0.000001404 0.50596 3.25203
77 4WZA ADP 0.00003429 0.57704 3.26087
78 4WZA ACP 0.00003429 0.57704 3.26087
79 1ZCB GDP 0.00000006203 0.6674 3.31492
80 3ZQ6 ADP ALF 0.00002245 0.54605 3.39506
81 3EWA ANP 0.0001728 0.47072 3.41615
82 5MEX PAP 0.009803 0.40818 3.41615
83 5MEX SZZ 0.02691 0.40818 3.41615
84 1OE0 TTP 0.005934 0.42865 3.47826
85 4GOX A3P 0.00008177 0.42994 3.51438
86 4H1V GNP 0.0000005947 0.5511 3.52304
87 2ZE7 AMP 0.002598 0.44445 3.55731
88 2ZE7 DST 0.002804 0.44445 3.55731
89 2Y65 ADP 0.000001188 0.50837 3.56164
90 5JCP GDP ALF 0.000000005388 0.62777 3.57995
91 3FVQ ATP 0.0003149 0.41982 3.62117
92 1IWE IMP 0.0001718 0.56212 3.72807
93 1F5N GNP 0.00009937 0.40407 3.72807
94 2ZPT A3P 0.02211 0.42518 3.72881
95 1G3M PCQ 0.01241 0.42627 3.7415
96 1G3M A3P 0.01241 0.42627 3.7415
97 4XGU ADP 0.00006325 0.50869 3.77358
98 2NCD ADP 0.000009632 0.56844 3.80952
99 2J5V PCA 0.02894 0.40932 3.81471
100 4E03 ADP 0.00001553 0.52819 3.8835
101 2OG2 MLI 0.000004278 0.41804 3.89972
102 4YDS ATP 0.00006097 0.52245 3.94737
103 2CE7 ADP 0.00007224 0.50057 3.94737
104 2ZTS ADP 0.0002911 0.42911 3.98406
105 1AQU A3P 0.003444 0.42756 4.0404
106 3BFV ADP 0.00002886 0.50715 4.05904
107 1GSA ADP 0.04004 0.40865 4.11392
108 4LJ9 ACP 0.0008611 0.44214 4.12979
109 1K6M AGS 0.00006876 0.51642 4.16667
110 2ZPA ADP 0.0001266 0.49706 4.16667
111 3T34 GDP 0.00000471 0.47862 4.16667
112 1BO4 COA 0.006606 0.41208 4.16667
113 2IYL GDP 0.00000178 0.57975 4.22535
114 1R6B ADP 0.0001235 0.48695 4.38596
115 4IEE AGS 0.001842 0.44346 4.38596
116 2CHG ANP 0.00009178 0.50114 4.42478
117 5G41 AP5 0.0008672 0.4913 4.4843
118 3DKP ADP 0.0003071 0.46076 4.4898
119 4FCW ADP 0.0002608 0.47209 4.50161
120 4U00 ADP 0.000006444 0.46429 4.5082
121 3B5J 12D 0.00006643 0.52061 4.52675
122 4HSE ADP 0.00003364 0.51282 4.53401
123 1OFH ADP 0.0001466 0.4864 4.5977
124 4R43 GDP 0.00005727 0.50897 4.60526
125 5IFS ADP 0.00006477 0.50275 4.60526
126 5TSH ANP 0.00003506 0.50116 4.60526
127 5TSH ADP 0.00006082 0.46101 4.60526
128 3A4M ADP 0.000003183 0.51956 4.61538
129 5M7P ADP 0.0002982 0.47957 4.62555
130 3UTU 1TS 0.01438 0.41876 4.6332
131 1V8K ANP 0.00006041 0.49172 4.63415
132 3B9Q MLI 0.000003959 0.58845 4.63576
133 3REF GDP 0.000000007667 0.57533 4.63918
134 1G6H ADP 0.000005066 0.59444 4.66926
135 4TMK T5A 0.004096 0.44478 4.69484
136 4RZ3 ADP 0.0000279 0.5253 4.74576
137 1JWY GDP 0.0000004298 0.60667 4.82456
138 1JWY ADP 0.0001965 0.47773 4.82456
139 2C9O ADP 0.00004985 0.45023 4.82456
140 2VF7 ADP 0.0008202 0.4493 4.82456
141 2D7D ADP 0.0006461 0.44719 4.82456
142 1JJV ATP 0.00002273 0.4748 4.85437
143 5HCN GCP 0.0000000008523 0.72326 4.98084
144 1Q20 A3P 0.007355 0.43214 5.01672
145 1Q20 PLO 0.007355 0.43214 5.01672
146 5HR5 ADP 0.00004671 0.51484 5.04386
147 4A4Z ANP 0.001287 0.44549 5.04386
148 5HR5 FLC 0.0162 0.41386 5.04386
149 1S3G AP5 0.0005931 0.49418 5.06912
150 5FTB ANP 0.0001044 0.47812 5.08083
151 5FHD ADP ALF 0.00009968 0.43739 5.08083
152 2XTZ GSP 0.00000001085 0.70393 5.08475
153 1W5T ANP 0.0005839 0.468 5.09709
154 1W5T ADP 0.001572 0.44348 5.09709
155 3KJI ADP 0.00001509 0.53493 5.11811
156 2B8W ALF 5GP 0.0001469 0.5027 5.18293
157 1BG2 ADP 0.0000003528 0.50759 5.23077
158 3VX3 ADP 0.00008818 0.50444 5.24194
159 2OFW ADX 0.0004833 0.49746 5.28846
160 2HF9 GSP 0.0000002676 0.56498 5.30973
161 1CS4 GSP 0.00000004174 0.5099 5.33333
162 4WOP CTP 0.0003956 0.476 5.33333
163 2BCG GDP 0.00000000004353 0.68583 5.33981
164 3CPJ GDP 0.000000000134 0.76944 5.38117
165 1JJ7 ADP 0.000003182 0.60634 5.38462
166 1IN4 ADP 0.00004094 0.5201 5.38922
167 1UKZ ADP 0.0008293 0.47922 5.41872
168 2QEN ADP 0.00002116 0.53091 5.42857
169 2W58 ADP 0.000001192 0.63227 5.44554
170 2O0J ADP 0.001623 0.41471 5.45455
171 1IHU ADP 0.00000872 0.55926 5.48246
172 1IHU AF3 0.000008996 0.5562 5.48246
173 1GXU 2HP 0.0003111 0.46969 5.49451
174 2EFE GNH 0.0000000006581 0.73736 5.52486
175 4DKX GDP 0.000000000004601 0.84214 5.55556
176 1NN5 ANP 0.0001409 0.51429 5.5814
177 4TTQ ATP 0.00006741 0.4905 5.5814
178 4P32 ADP 0.0007022 0.46625 5.62249
179 1XKV ATP 0.0001692 0.48352 5.70175
180 2IS6 ADP 0.00008997 0.4827 5.70175
181 2XAU ADP 0.001084 0.44632 5.70175
182 2Z5F A3P 0.004295 0.427 5.7047
183 1Z08 GNP 0.000000001189 0.5917 5.88235
184 5K04 COA 0.01087 0.41127 5.88235
185 2FSH ANP 0.001069 0.42995 5.92105
186 1NY5 ADP 0.0002809 0.47844 5.94315
187 3DZD ADP 0.0004899 0.46476 5.97826
188 4QOS ADP 0.0002229 0.4633 6.03774
189 2QZ4 ADP 0.00003731 0.5138 6.10687
190 5GJC ATP 0.00009562 0.48196 6.1086
191 2GK6 ADP 0.001244 0.418 6.14035
192 3QKT ANP 0.00119 0.45907 6.19469
193 3BOS CDP 0.00007148 0.48758 6.19835
194 1S8F GDP 0.0000000001395 0.80138 6.21469
195 1Z6T ADP 0.000106 0.4546 6.26058
196 2RGX AP5 0.0008258 0.48918 6.31068
197 3IO3 ADP 0.00003409 0.52384 6.32184
198 2WKQ GTP 0.000000003348 0.57399 6.3253
199 5CK5 GDP 0.000000001556 0.68 6.32911
200 1G6O ADP 0.0001734 0.46803 6.36364
201 4QM7 GTP 0.00005891 0.49139 6.43275
202 1GOJ ADP 0.0000004781 0.64666 6.47887
203 4GBM A3P 0.0004196 0.40652 6.50155
204 1M7B GTP 0.000000001867 0.61326 6.52174
205 1Y63 ADP 0.0000102 0.52523 6.52174
206 2F9L GDP 0.0000000001452 0.61824 6.53266
207 2QG6 NMN 0.0002168 0.50012 6.53266
208 5WRI A3P 0.001482 0.45083 6.5625
209 3T1O GDP 0.00000001654 0.66843 6.56566
210 3V2U ATP 0.01404 0.40429 6.621
211 3BC1 GNP 0.0000000001408 0.79493 6.66667
212 4J0Q GDP 0.00000000004188 0.81192 6.69746
213 2Y8E GNP 0.0000000001645 0.59007 6.70391
214 2B8T THM 0.002952 0.43659 6.72646
215 4ZG4 VO4 ADP 0.0002554 0.48919 6.79825
216 4IHQ ADP 0.00008727 0.47378 6.79825
217 1OIV GDP 0.0000000001028 0.80151 6.80628
218 1OIX GDP 0.0000000001915 0.78849 6.80628
219 4YMU ATP 0.00007332 0.4761 6.81818
220 5KSZ GCP 0.00000009957 0.63248 6.83962
221 5SZH GNP 0.0000000001304 0.79973 6.89655
222 1RYH GNP 0.0000000005364 0.7371 6.89655
223 2BME GNP 0.0000000002189 0.78568 6.98925
224 3EC1 GDP 0.0000000002484 0.74777 7.04607
225 4M9Q GNP 0.000000000535 0.61947 7.04846
226 1YZQ GNP 0.0000000000856 0.80858 7.05882
227 1G16 GDP 0.0000000006784 0.75212 7.05882
228 1JI0 ATP 0.00003869 0.53224 7.08333
229 1U0J ADP 0.0004924 0.44315 7.11611
230 3QBT GNP 0.0000000001048 0.59182 7.14286
231 1ZUI SKM 0.0003416 0.50114 7.14286
232 4RD0 GDP 0.0000000001046 0.7907 7.22892
233 4PFO ADP 0.0004336 0.48198 7.23684
234 4WZ6 ATP 0.00003795 0.46633 7.24138
235 1VG8 GNP 0.0000000001355 0.79892 7.24638
236 1VG0 GDP 0.00000000005401 0.78777 7.24638
237 1B0U ATP 0.0003764 0.47007 7.25191
238 1Z0F GDP 0.00000000001483 0.80381 7.26257
239 1E96 GTP 0.000000004848 0.7208 7.29167
240 1I4D GDP 0.0000000003363 0.70456 7.29167
241 2OZE AGS 0.0001915 0.48861 7.38255
242 4BQS ADP 0.00003047 0.52184 7.38636
243 4BQS K2Q 0.0002887 0.50479 7.38636
244 2C77 GNP 0.0000000003983 0.75948 7.40741
245 2C78 GNP 0.0000000001205 0.63886 7.40741
246 4JLV ADP 0.0003107 0.45442 7.43494
247 4LPS GDP 0.00000005865 0.63912 7.43802
248 5JCZ GDP 0.0000000001463 0.66521 7.45614
249 4LX0 BEF GDP 0.0000000001312 0.79959 7.49415
250 3KTA AP5 0.0004755 0.4394 7.51445
251 1MH1 GNP 0.000000003033 0.73351 7.52688
252 4PX9 ADP 0.0001527 0.46534 7.53425
253 2HV8 GTP 0.0000000001286 0.79682 7.55814
254 1Z0K GTP 0.00000000008408 0.62311 7.55814
255 1G4U GDP 0.000000002369 0.62255 7.6087
256 4ZNL BEF ADP 0.00004873 0.50545 7.66423
257 4ZKD GDP 0.000000003809 0.72872 7.67544
258 1VKJ A3P 0.01161 0.40651 7.7193
259 1OW3 GDP 0.000000003323 0.70864 7.77202
260 2D7C GTP 0.0000000001427 0.79465 7.78443
261 1VHT BA3 0.0002914 0.47264 7.79817
262 5GOE GDP 0.0000000005603 0.70762 7.81991
263 2FJU GSP 0.000000001567 0.73135 7.86517
264 3TMK T5A 0.0001871 0.50495 7.87037
265 5KUT GDP 0.000000008789 0.67686 7.93651
266 2CBZ ATP 0.0000007497 0.64374 8.01688
267 4LHW GNP 0.0000000002988 0.58013 8.04598
268 1KK1 GNP 0.0000000000959 0.73057 8.04878
269 1M7G AV2 0.000004121 0.5319 8.05687
270 1M7G ADX 0.00006187 0.5319 8.05687
271 1M7G ADP 0.00008665 0.52129 8.05687
272 5IRC GDP 0.00000002388 0.66107 8.06452
273 1LVG ADP 0.000002642 0.52704 8.08081
274 1VG1 GDP 0.00000000001791 0.80006 8.10811
275 1VG9 GDP 0.00000000002671 0.79212 8.10811
276 4D0N GDP 0.0000000005637 0.71296 8.10811
277 5HPY GDP 0.000000002925 0.71122 8.10811
278 3LXR GDP 0.000000002629 0.67834 8.10811
279 1KMQ GNP 0.000000007926 0.70455 8.15217
280 4V03 ADP 0.0000378 0.51354 8.17121
281 3ZIA ATP 0.00001375 0.53061 8.19672
282 3ZIA ADP 0.00002012 0.52913 8.19672
283 3RAB GNP 0.0000000000256 0.83063 8.28402
284 2PZE ATP 0.000008421 0.4749 8.29694
285 5TIV A3P 0.005201 0.44947 8.3004
286 3H86 AP5 0.0002479 0.50669 8.33333
287 1KAO GDP 0.0000000006014 0.74332 8.38323
288 1L5Y BEF 0.01051 0.4155 8.3871
289 3MD0 GDP 0.00000000007555 0.73242 8.4507
290 1W0J ADP 0.000006522 0.55184 8.45588
291 1W0J ADP BEF 0.0002966 0.47968 8.45588
292 1TX4 ALF GDP 0.000000009704 0.56121 8.47458
293 3UIE ANP 0.00004112 0.51185 8.5
294 1DAR GDP 0.0000000006779 0.71255 8.55263
295 2F3R G5P 0.02079 0.40846 8.69565
296 1QF9 ALF 0.00127 0.4739 8.76289
297 1QF9 ADP 0.00127 0.4739 8.76289
298 1QF9 C5P 0.00127 0.4739 8.76289
299 4YS0 ADP 0.0005113 0.4322 8.77193
300 1NJF ADP 0.00005026 0.51592 8.8
301 1NJF AGS 0.00007064 0.51366 8.8
302 3T12 GDP ALF 0.00000002122 0.56807 8.82353
303 3U6B GDP 0.00000000000287 0.86804 8.88325
304 4G5G GDP 0.00000000001576 0.81703 8.88325
305 3U6K GDP 0.00000000001674 0.8158 8.88325
306 5JBQ GDP 0.00000000001198 0.78668 8.88325
307 4P3Y GDP 0.000000000004703 0.78212 8.88325
308 4PC3 GDP 0.0000000002818 0.75446 8.88325
309 4CVN ADP 0.000002162 0.5943 8.90052
310 1D8T GDP 0.00000000001194 0.78691 8.90585
311 2BVN GNP 0.00000000006446 0.72441 8.90585
312 1Z2A GDP 0.0000000009551 0.59402 8.92857
313 3RLF ANP 0.0002752 0.48764 8.94737
314 3E5H GNP 0.00000000248 0.73483 8.98876
315 1D2E GDP 0.00000000005274 0.78825 9.06801
316 3TK1 GDP 0.00000000002941 0.72985 9.09091
317 3MGB PAP 0.01302 0.40415 9.09091
318 4XSH GSP 0.000000003467 0.7115 9.13242
319 3NKV GNP 0.0000000001148 0.79919 9.14286
320 1Z0A GDP 0.0000000000356 0.79142 9.1954
321 3BD9 A3P 0.008944 0.40172 9.28571
322 3WXM GTP 0.0000000004537 0.77041 9.42982
323 1R0X ATP 0.0002459 0.45645 9.44056
324 3IIJ ADP 0.000005527 0.53696 9.44444
325 4LC1 GDP 0.0000000001989 0.76532 9.49555
326 2PEZ DAT 0.0003323 0.49746 9.49721
327 2PEZ GGZ 0.0003323 0.49746 9.49721
328 1UJ2 C5P 0.0002133 0.49868 9.52381
329 1UJ2 ADP 0.0003369 0.48906 9.52381
330 2DPY ADP 0.0001049 0.51077 9.58904
331 3VMF GTP 0.00000000008442 0.80564 9.65147
332 1YZN GNP 0.0000000001449 0.57715 9.72973
333 5J1S ATP 0.000532 0.47586 9.7561
334 2RCN GDP 0.0000000000599 0.75627 9.77654
335 1SKQ GDP 0.0000000003396 0.70697 9.88506
336 1SVK ALF GDP 0.00000002689 0.69511 9.91501
337 1GP2 GDP 0.0000001206 0.53434 9.91501
338 2ZR9 DTP 0.00007378 0.5038 10.0287
339 2VB6 ADP BEF 0.0004751 0.47631 10.0671
340 3IUY AMP 0.006402 0.40346 10.0877
341 2G77 GDP 0.00000000001654 0.72342 10.101
342 2G77 AF3 0.006203 0.42786 10.101
343 4PPF FLC 0.000003799 0.5965 10.2857
344 5IRR GSP 0.0000007123 0.50915 10.3896
345 1DS6 GDP 0.0000000002351 0.72951 10.4167
346 2HCJ GDP 0.000000000002016 0.79657 10.4478
347 1CXZ GSP 0.000000008064 0.70103 10.4651
348 1G3Q ADP 0.00006325 0.50026 10.5485
349 1Y3A GDP 0.0000001069 0.65057 10.6383
350 3FB4 AP5 0.0006019 0.49385 10.6481
351 4XOI GTP 0.00000001478 0.69459 10.7407
352 2OM2 GDP 0.00000009369 0.5605 10.7692
353 3LRE ADP 0.000001657 0.61397 10.9859
354 4XTR ATP 0.00004755 0.52407 11.0599
355 4XTR ADP 0.00003501 0.5233 11.0599
356 4XVU ATP 0.00005413 0.52138 11.0599
357 2IXE ATP 0.0004355 0.47612 11.0701
358 4Q1A UDP 0.001337 0.5282 11.0714
359 4Q1A 2XZ 0.001337 0.5282 11.0714
360 1BH2 GSP 0.0000001195 0.66105 11.1111
361 4C4P GNP 0.00000000007729 0.81073 11.215
362 2FH5 GTP 0.0000000003641 0.76132 11.215
363 3Q72 GNP 0.000000000006729 0.77531 11.4458
364 3TNF GNP 0.0000000003177 0.78398 11.4583
365 1H65 GDP 0.000002581 0.58197 11.4815
366 3SBD GNP 0.000000005371 0.71865 11.7647
367 4KFU ACP 0.000004754 0.50488 11.7925
368 4LYA ATP 0.00002024 0.52292 11.8421
369 1HE1 GDP 0.000000002113 0.60877 11.8519
370 1A4R GDP 0.000000001273 0.73196 12.0419
371 1A4R GNH 0.000000001222 0.72893 12.0419
372 2NGR GDP 0.000000001054 0.71904 12.0419
373 1GRN GDP 0.000000002581 0.71376 12.0419
374 4ITR GDP 0.000000004506 0.70615 12.0419
375 1XX6 ADP 0.0005645 0.44746 12.0419
376 3BER AMP 0.006271 0.41314 12.0482
377 1B7T ADP 0.0004731 0.44999 12.1795
378 3SFV GDP 0.0000000001197 0.78416 12.2093
379 1KK8 BEF ADP 0.0002645 0.441 12.3377
380 2XTN GTP 0.0000006946 0.50282 12.3932
381 1PUJ GNP 0.0000000001153 0.77248 12.4113
382 5MZN ADP 0.0006779 0.43034 12.5
383 1T8U UAP SGN IDS SGN 0.02401 0.41265 12.5
384 1T8U A3P 0.00875 0.41235 12.5
385 4YC7 GNP 0.000000003667 0.71729 12.7072
386 1NF3 GNP 0.000000007781 0.71089 12.8205
387 1D2N ANP 0.0007891 0.46182 12.8676
388 1FQJ GDP 0.00000002266 0.55639 12.9231
389 1FQK GDP 0.0000001365 0.5342 12.9231
390 1FQJ ALF 0.01497 0.40794 12.9231
391 1FQK ALF 0.01504 0.40786 12.9231
392 3CNL GNP 0.0000000004998 0.6981 12.9771
393 3DOE GTP 0.0000000001526 0.7865 13.0208
394 5L3V GDP 0.000001238 0.58201 13.0435
395 4OI4 ATP 0.000175 0.49704 13.0435
396 5L3S GNP 0.00000132 0.60094 13.0872
397 1WDT GTP 0.0000007711 0.53293 13.1579
398 5H56 ADP 0.000234 0.50185 13.3333
399 5H56 TYD 0.000234 0.50185 13.3333
400 4R2I ANP 0.001018 0.42805 13.3333
401 1G7S GDP 0.0000000002258 0.74967 13.3772
402 1KSH GDP 0.000000000035 0.8094 13.4409
403 5FG3 GDP 0.000000000003565 0.787 13.5965
404 4NCN GTP 0.0000000001771 0.78341 13.5965
405 2WMO GTP 0.000000002517 0.70614 13.6842
406 1GOT GDP 0.0000001557 0.63993 13.6986
407 4D81 ADP 0.00005338 0.50945 13.7809
408 5M04 GDP 0.00000000003354 0.74984 14.0351
409 5N69 ADP 0.0001902 0.48384 14.0704
410 1F2U ATP 0.002503 0.44685 14.094
411 1TAD ALF 0.00000003062 0.68994 14.1975
412 1TAD GDP 0.00000003062 0.68994 14.1975
413 2EW1 GNP 0.0000000001191 0.79163 14.4279
414 1RRC ADP 0.000008264 0.47587 14.6179
415 5J1J ANP 0.00001092 0.5546 14.7368
416 1UAD GNP 0.0000000005409 0.76673 14.8571
417 5KSP GDP 0.00000004731 0.64339 15.2632
418 5BXQ GDP 0.0000000001017 0.76553 15.2778
419 4HAT GNP 0.000000001871 0.74651 15.2778
420 3CH5 GDP 0.0000000002756 0.7457 15.2778
421 1IBR GNP 0.000000001729 0.54869 15.2778
422 1ZC3 GNP 0.0000000003206 0.7808 15.4286
423 1U8Z GDP 0.0000000005221 0.59984 15.4762
424 3M1I GTP 0.00000000233 0.73906 15.5251
425 3WYF GTP 0.000000003141 0.73557 15.5251
426 3TKL GTP 0.0000000001162 0.60488 15.7303
427 3GJX GTP 0.000000003311 0.73167 15.7407
428 2C04 GCP 0.00009312 0.467 15.8249
429 4D0G GTP 0.00000000007615 0.79726 15.942
430 2V7Q ATP 0.000006177 0.54982 16
431 2V7Q ADP 0.0001671 0.47235 16
432 2CK3 ANP 0.0003316 0.4309 16
433 2CK3 ADP 0.0003272 0.40903 16
434 1NRJ GTP 0.00000004102 0.66433 16.055
435 1GWN GTP 0.000000004792 0.70841 16.0976
436 3WY9 GDP 0.000000000005258 0.85536 16.3594
437 3WYA GDP 0.00000000002281 0.7749 16.3594
438 3W5J GDP 0.00000004078 0.56549 16.6667
439 4QRH 0O2 0.003324 0.43227 16.6667
440 2W2X GSP 0.00000000147 0.73266 16.9355
441 5X40 ACP 0.000816 0.46509 17.4658
442 4TMZ GSP 0.0000000001434 0.61889 17.6812
443 1KO8 6PG 0.0001516 0.49338 17.7143
444 1YVD GNP 0.0000000001464 0.58985 17.7515
445 2KIN ADP 0.0000003778 0.50668 18
446 2A9K GDP 0.0000000002672 0.75978 18.3857
447 3WYG GTP 0.000000003822 0.73142 18.6813
448 2OBM ADP 0.0001322 0.51665 18.732
449 2BEK ATP 0.0002695 0.41966 19.0661
450 3DEF GDP 0.0000008305 0.59339 19.4656
451 4BAS GNP 0.00000001553 0.6875 19.598
452 5WRJ A3P 0.001326 0.45682 19.802
453 1W7J ADP BEF 0.0002938 0.43875 19.8675
454 1G7C 5GP 0.00000001168 0.68226 20.2128
455 4KVG GTP 0.0000000003467 0.77605 20.2381
456 3X1Z GNP 0.000000000531 0.77313 20.3593
457 4HDO GNP 0.0000000005516 0.76938 20.3593
458 4HDQ GNP 0.000000001069 0.75547 20.3593
459 2A5J GDP 0.00000000002309 0.76618 20.4188
460 1WF3 GNP 0.0000000002233 0.78841 20.598
461 1GUA GNP 0.0000000006259 0.55948 20.9877
462 2WJH GDP 0.0000000004261 0.73704 21.0843
463 2WJH FLC 0.0000002351 0.61528 21.0843
464 4B47 GDP 0.00000000000448 0.78314 21.2121
465 1Z0J GTP 0.0000000002551 0.57173 22.0339
466 1M2O GNP 0.000000006562 0.71445 22.1053
467 5L3R GCP 0.00000084 0.49118 23.588
468 4HI0 GDP 0.0000004073 0.53581 23.622
469 1XTQ GDP 0.0000000001565 0.78597 24.2938
470 4MKF AP5 0.0006294 0.49404 24.424
471 3GJ0 GDP 0.00000000004278 0.79666 24.4344
472 3GJ7 GDP 0.00000000004537 0.79547 24.4344
473 3GJ8 GDP 0.000000000128 0.76096 24.4344
474 3GJ4 GDP 0.00000000004781 0.76016 24.4344
475 3GJ5 GDP 0.0000000001506 0.75772 24.4344
476 3GJ3 GDP 0.00000000006639 0.75419 24.4344
477 5UWU GNP 0.000000001536 0.74783 24.4726
478 5UWW GNP 0.000000001539 0.7478 24.4726
479 5DIF GNP 0.000000001561 0.74749 24.4726
480 5UWP GNP 0.000000001824 0.74705 24.4726
481 5DHF GNP 0.000000001716 0.7455 24.4726
482 5UWR GNP 0.000000001842 0.74401 24.4726
483 5UWI GNP 0.000000001896 0.7434 24.4726
484 5UWS GNP 0.000000002348 0.74171 24.4726
485 5UWT GNP 0.000000002069 0.74157 24.4726
486 5DI9 GNP 0.000000002372 0.7415 24.4726
487 5UWQ GNP 0.000000001437 0.55099 24.4726
488 5UWJ GNP 0.000000001727 0.54888 24.4726
489 5UWO GNP 0.000000001807 0.54855 24.4726
490 5UWH GNP 0.000000002176 0.54661 24.4726
491 1Z06 GNP 0.0000000000537 0.81171 24.8677
492 4MKG AP5 0.000657 0.49193 24.8848
493 2QTV GNP 0.00000001463 0.69481 25.1497
494 4NON GDP 0.000000001432 0.54248 25.3846
495 4R98 GNH 0.000000009635 0.66125 26.1993
496 1YZG GDP 0.0000000003915 0.73873 26.257
497 1F6B GDP 0.00000000231 0.70343 26.2626
498 4YLG GDP 0.0000000004114 0.75102 27.1676
499 1WA5 GTP 0.000000003088 0.50396 27.2727
500 2A5F GTP 0.00000001039 0.70194 27.4286
501 4DSU GDP 0.0000000001432 0.79775 27.5132
502 2QN6 GDP 0.000000000002242 0.7952 27.7778
503 5TB5 GDP 0.0000000000385 0.78985 28.1081
504 5TAR GDP 0.00000000005143 0.72599 28.1081
505 3AQ4 GDP 0.000000001338 0.71428 28.2609
506 4ZI2 GNP 0.000000000149 0.78341 28.9474
507 3PCR GTP 0.000000004451 0.57612 29.0123
508 3A1S GDP 0.00000001142 0.67166 29.0698
509 4GOJ GNP 0.0000000002037 0.77695 29.1005
510 2WIC GNP 0.000000004383 0.6907 29.2135
511 1ZJ6 G3D 0.0000000002249 0.74975 29.4118
512 3N5C GDP 0.0000000006789 0.74029 29.6296
513 2W83 GTP 0.000000003782 0.57886 29.697
514 4DID GDP 0.000000001943 0.70687 30.0518
515 4KAX GTP 0.000000002622 0.72422 30.1775
516 1FZQ GDP 0.00000000002973 0.7704 30.3867
517 2X77 GDP 0.0000000004659 0.73527 30.6878
518 5XCO GDP 0.0000000000276 0.8013 31.5789
519 4K81 GTP 0.000000001028 0.75918 31.5789
520 2C5L GTP 0.0000000002516 0.7859 31.7919
521 5DI3 GNP 0.0000000004165 0.6227 31.8919
522 2GJ8 ALF GDP 0.0000000001571 0.58164 31.9767
523 5E95 GDP 0.000000000179 0.68369 32.1429
524 1LFD GNP 0.0000000001995 0.78762 32.3353
525 3KUD GDP 0.0000000001104 0.78581 32.5301
526 1NVV GNP 0.0000000002602 0.78519 32.5301
527 5UFQ GNP 0.0000000002426 0.78352 32.5301
528 3DDC GNP 0.0000000002825 0.78346 32.5301
529 2UZI GTP 0.0000000004242 0.77182 32.5301
530 1WQ1 GDP 0.0000000004451 0.60274 32.5301
531 1CLU DBG 0.000000001148 0.78702 33.1325
532 1NVU GTP 0.0000000003445 0.77928 33.1325
533 1X1R GDP 0.0000000007704 0.76235 33.1461
534 1D5C GDP 0.00000000006805 0.78753 33.3333
535 5O2T GSP 0.000000000336 0.56738 33.7278
536 2FFQ GSP 0.0000000001872 0.79212 35.0877
537 1SVI GDP 0.00000000001438 0.76193 35.8974
538 2WJG GDP 0.0000000001442 0.77188 36.1702
539 1ZD9 GDP 0.000000003497 0.62119 38.8298
540 5UQW GDP 0.0000000001582 0.78919 39.1534
541 2ZEJ GDP 0.00000002457 0.6895 39.6739
542 5WDR GNP 0.0000000003281 0.78031 39.7661
543 1MR3 G3D 0.000000001284 0.7151 40.3315
544 1R4A GNP 0.000000000686 0.7586 41.2121
545 4V0K GDP 0.000000002451 0.5708 42.0118
546 1TU3 GNP 0.00000000005624 0.81415 42.1053
547 1R2Q GNP 0.0000000001464 0.81673 42.3529
548 3MJH GTP 0.00000000007136 0.59851 43.4524
549 1UPT GTP 0.000000002669 0.72385 43.8596
550 5EE5 GTP 0.0000000004418 0.76097 44.4444
551 1RE0 GDP 0.0000000001928 0.71719 45.122
552 1S9D GDP 0.000000002156 0.70481 45.122
553 1O3Y GTP 0.000000004203 0.71771 45.7831
554 2J59 GTP 0.000000002877 0.58099 45.7831
555 1J2J GTP 0.000000003051 0.57899 45.7831
Pocket No.: 2; Query (leader) PDB : 4DCT; Ligand: GDP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4dct.bio1) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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