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Receptor
PDB id Resolution Class Description Source Keywords
4DSG 2.25 Å EC: 5.4.99.9 CRYSTAL STRUCTURE OF OXIDIZED UDP-GALACTOPYRANOSE MUTASE TRYPANOSOMA CRUZI ROSSMANN FOLD FLAVIN ADENINE DINUCLEOTIDE ISOMERASE
Ref.: CRYSTAL STRUCTURES OF TRYPANOSOMA CRUZI UDP-GALACTO MUTASE IMPLICATE FLEXIBILITY OF THE HISTIDINE LOOP ACTIVATION. BIOCHEMISTRY V. 51 4968 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FAD A:501;
B:501;
Valid;
Valid;
none;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
SO4 A:503;
Invalid;
none;
submit data
96.063 O4 S [O-]S...
UDP A:502;
B:502;
Valid;
Valid;
none;
none;
submit data
404.161 C9 H14 N2 O12 P2 C1=CN...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4DSG 2.25 Å EC: 5.4.99.9 CRYSTAL STRUCTURE OF OXIDIZED UDP-GALACTOPYRANOSE MUTASE TRYPANOSOMA CRUZI ROSSMANN FOLD FLAVIN ADENINE DINUCLEOTIDE ISOMERASE
Ref.: CRYSTAL STRUCTURES OF TRYPANOSOMA CRUZI UDP-GALACTO MUTASE IMPLICATE FLEXIBILITY OF THE HISTIDINE LOOP ACTIVATION. BIOCHEMISTRY V. 51 4968 2012
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 4DSG - UDP C9 H14 N2 O12 P2 C1=CN(C(=O....
2 4DSH - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 6 families.
1 4DSG - UDP C9 H14 N2 O12 P2 C1=CN(C(=O....
2 4DSH - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
50% Homology Family (19)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 3UTH - GDU C15 H24 N2 O17 P2 C1=CN(C(=O....
2 4U8J - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
3 4U8P - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
4 3UTF - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
5 4U8L - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
6 3UTE - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
7 4U8M - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
8 3UKH - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
9 4WX1 - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
10 4U8N - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
11 4U8O - UDP C9 H14 N2 O12 P2 C1=CN(C(=O....
12 3UTG - UDP C9 H14 N2 O12 P2 C1=CN(C(=O....
13 4U8K - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
14 3UKF - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
15 5HHF - 62F C33 H45 N9 O20 P2 Cc1cc2c(cc....
16 4U8I - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
17 4GDE - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
18 4DSG - UDP C9 H14 N2 O12 P2 C1=CN(C(=O....
19 4DSH - FDA C27 H35 N9 O15 P2 Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FAD; Similar ligands found: 128
No: Ligand ECFP6 Tc MDL keys Tc
1 FAD 1 1
2 FAS 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 FAE 0.751773 0.987654
7 SFD 0.651007 0.860215
8 FDA 0.641892 0.906977
9 FNK 0.602564 0.876405
10 62F 0.572327 0.939024
11 F2N 0.566265 0.886364
12 FMN 0.543307 0.876543
13 FA9 0.526316 0.939759
14 6YU 0.516304 0.860215
15 P6G FDA 0.511628 0.908046
16 FAD NBT 0.508876 0.83871
17 A2D 0.504065 0.875
18 P5F 0.491329 0.941176
19 FAD CNX 0.488506 0.8125
20 AR6 0.488372 0.851852
21 APR 0.488372 0.851852
22 AGS 0.484615 0.811765
23 SAP 0.484615 0.811765
24 M33 0.484375 0.864198
25 BA3 0.484127 0.875
26 HEJ 0.48062 0.851852
27 ATP 0.48062 0.851852
28 ADP 0.480315 0.851852
29 B4P 0.480315 0.875
30 AP5 0.480315 0.875
31 ANP 0.477273 0.831325
32 AQP 0.476923 0.851852
33 5FA 0.476923 0.851852
34 48N 0.469388 0.902439
35 OAD 0.467626 0.876543
36 9X8 0.467626 0.833333
37 FAD NBA 0.467033 0.793814
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AT4 0.465116 0.821429
41 AD9 0.462121 0.831325
42 3OD 0.460993 0.876543
43 RBF 0.460938 0.790123
44 FB0 0.460606 0.835165
45 139 0.460526 0.858824
46 AP0 0.46 0.835294
47 A22 0.459854 0.864198
48 ACP 0.458015 0.853659
49 8QN 0.456522 0.864198
50 PRX 0.454545 0.831325
51 A3R 0.453237 0.86747
52 A1R 0.453237 0.86747
53 G3A 0.452055 0.902439
54 T5A 0.45098 0.872093
55 G5P 0.44898 0.902439
56 ATF 0.448529 0.821429
57 50T 0.44697 0.819277
58 6YZ 0.445255 0.853659
59 ACQ 0.444444 0.853659
60 CNV FAD 0.443182 0.917647
61 ADQ 0.442857 0.853659
62 PAJ 0.442857 0.847059
63 5AL 0.441176 0.864198
64 ADX 0.439394 0.775281
65 CA0 0.439394 0.853659
66 A4P 0.437909 0.831461
67 25L 0.4375 0.864198
68 P33 FDA 0.436464 0.817204
69 5SV 0.435714 0.793103
70 OMR 0.434211 0.818182
71 TXE 0.434211 0.890244
72 ABM 0.434109 0.829268
73 A 0.433071 0.82716
74 AMP 0.433071 0.82716
75 4AD 0.432624 0.855422
76 ADJ 0.432258 0.818182
77 B5M 0.431507 0.878049
78 B5Y 0.431507 0.878049
79 BIS 0.430556 0.802326
80 SRA 0.429688 0.788235
81 AFH 0.42953 0.825581
82 NXX 0.427632 0.865854
83 DND 0.427632 0.865854
84 UP5 0.427632 0.878049
85 6V0 0.427632 0.857143
86 TXD 0.427632 0.890244
87 DQV 0.426667 0.8875
88 SRP 0.42446 0.843373
89 PR8 0.423611 0.837209
90 T99 0.423358 0.821429
91 TAT 0.423358 0.821429
92 AMO 0.422535 0.865854
93 TXA 0.42069 0.865854
94 FYA 0.42069 0.864198
95 PTJ 0.42069 0.835294
96 CNA 0.420382 0.865854
97 00A 0.41958 0.823529
98 AHX 0.41958 0.835294
99 MAP 0.41844 0.811765
100 NAI 0.418301 0.845238
101 AU1 0.41791 0.831325
102 A12 0.416667 0.843373
103 AP2 0.416667 0.843373
104 25A 0.415493 0.851852
105 9ZA 0.415493 0.845238
106 9ZD 0.415493 0.845238
107 COD 0.415094 0.842697
108 4TC 0.412903 0.879518
109 APC 0.411765 0.843373
110 ME8 0.410959 0.806818
111 1ZZ 0.410959 0.806818
112 NB8 0.410959 0.835294
113 4UW 0.409091 0.825581
114 NAX 0.409091 0.837209
115 F2R 0.408805 0.850575
116 RBY 0.408759 0.843373
117 ADV 0.408759 0.843373
118 P1H 0.405882 0.818182
119 OOB 0.405594 0.864198
120 LAD 0.40411 0.825581
121 A A 0.40411 0.829268
122 UPA 0.403846 0.86747
123 4UU 0.401316 0.833333
124 GA7 0.401316 0.865854
125 A3D 0.401235 0.876543
126 80F 0.401235 0.808989
127 XAH 0.4 0.806818
128 DLL 0.4 0.864198
Ligand no: 2; Ligand: UDP; Similar ligands found: 117
No: Ligand ECFP6 Tc MDL keys Tc
1 UDP 1 1
2 UTP 0.892308 1
3 UNP 0.8 0.970149
4 U5P 0.78125 0.984615
5 U 0.78125 0.984615
6 UPU 0.72973 0.940298
7 2KH 0.722222 0.970149
8 44P 0.720588 0.955882
9 UFM 0.717949 0.941176
10 GDU 0.717949 0.941176
11 URM 0.717949 0.927536
12 660 0.717949 0.927536
13 UPG 0.717949 0.941176
14 GUD 0.717949 0.941176
15 UDP UDP 0.714286 0.939394
16 UPP 0.705128 0.941176
17 UDH 0.705128 0.864865
18 U2F 0.691358 0.888889
19 UFG 0.691358 0.888889
20 UPF 0.691358 0.888889
21 UAD 0.670732 0.941176
22 UDX 0.670732 0.941176
23 3UC 0.658824 0.888889
24 USQ 0.654762 0.820513
25 UGB 0.654762 0.955224
26 UGA 0.654762 0.955224
27 G3N 0.647059 0.914286
28 UDM 0.636364 0.914286
29 URI 0.625 0.863636
30 UD1 0.622222 0.927536
31 UD2 0.622222 0.927536
32 Y6W 0.607143 0.888889
33 CDP 0.605263 0.942029
34 HP7 0.591398 0.941176
35 UD7 0.591398 0.927536
36 MJZ 0.585106 0.914286
37 IUG 0.583333 0.810127
38 F5G 0.578947 0.927536
39 12V 0.578947 0.901408
40 HWU 0.578947 0.901408
41 F5P 0.578947 0.914286
42 UD4 0.578947 0.914286
43 CJB 0.573529 0.820895
44 UDZ 0.571429 0.853333
45 DUD 0.571429 0.913043
46 UP5 0.571429 0.853333
47 U U 0.563218 0.955224
48 EPZ 0.56 0.914286
49 5GW 0.559524 0.942029
50 EPU 0.554455 0.901408
51 EEB 0.554455 0.901408
52 U3P 0.547945 0.939394
53 UA3 0.547945 0.939394
54 4TC 0.544554 0.831169
55 HF4 0.54321 0.942029
56 CTP 0.54321 0.942029
57 CSQ 0.531915 0.851351
58 CSV 0.531915 0.851351
59 DUT 0.52439 0.913043
60 4GW 0.516484 0.915493
61 UMA 0.513761 0.914286
62 U4S 0.513158 0.753425
63 U2P 0.506667 0.954545
64 U2S 0.5 0.767123
65 U3S 0.5 0.753425
66 PUP 0.48913 0.913043
67 U21 0.486957 0.810127
68 U20 0.486957 0.810127
69 U22 0.486957 0.790123
70 DKX 0.486486 0.746479
71 U1S 0.482759 0.75
72 A U 0.481132 0.805195
73 2QR 0.478632 0.822785
74 5FU 0.474359 0.914286
75 G U 0.472222 0.7875
76 8OD 0.47191 0.851351
77 C5G 0.468085 0.888889
78 7XL 0.465909 0.888889
79 U U U U 0.461538 0.940298
80 UMF 0.461538 0.857143
81 G8D 0.460674 0.855263
82 UTP U U U 0.456522 0.895522
83 2TU 0.452055 0.774648
84 4RA 0.451613 0.855263
85 C2G 0.450549 0.901408
86 DU 0.45 0.898551
87 UMP 0.45 0.898551
88 C 0.45 0.927536
89 CAR 0.45 0.927536
90 C5P 0.45 0.927536
91 UAG 0.448 0.864865
92 CDC 0.446809 0.777778
93 5BU 0.444444 0.914286
94 UD0 0.444444 0.844156
95 N3E 0.440476 0.733333
96 UC5 0.440476 0.9
97 UUA 0.438356 0.772727
98 DUP 0.431818 0.887324
99 2GW 0.431373 0.901408
100 M7G 0.430108 0.780488
101 CNU 0.428571 0.927536
102 CDM 0.427083 0.842105
103 H6Y 0.425532 0.851351
104 16B 0.421687 0.888889
105 S5P 0.419753 0.915493
106 8GT 0.419355 0.855263
107 CXY 0.418367 0.888889
108 UPA 0.418182 0.842105
109 U2G 0.410714 0.822785
110 U A A U 0.409836 0.842105
111 UML 0.408759 0.810127
112 UP6 0.407407 0.871429
113 M7M 0.40625 0.771084
114 1GW 0.40367 0.864865
115 BMP 0.402439 0.970149
116 APU 0.401786 0.828947
117 PMP UD1 0.401575 0.7875
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4DSG; Ligand: FAD; Similar sites found with APoc: 892
This union binding pocket(no: 1) in the query (biounit: 4dsg.bio2) has 59 residues
No: Leader PDB Ligand Sequence Similarity
1 1TUK PGM None
2 1GYY FHC None
3 5WGR FAD 1.03306
4 1MV8 NAD 1.14679
5 1MUU NAD 1.14679
6 3G4G D71 1.18765
7 3HWW AKG 1.23967
8 1P31 EPU 1.26316
9 1P3D UMA 1.26316
10 4DMG SAM 1.27226
11 3G58 988 1.31234
12 3P2E SAH 1.33333
13 5OFW 9TW 1.34529
14 4C4A SAH 1.44628
15 5CX8 TG6 1.4553
16 3PT9 SAH 1.48912
17 4ZNO SUC 1.49254
18 6CEP NAD 1.49701
19 6CEP OXM 1.49701
20 5N53 8NB 1.53846
21 5K4W NAI 1.55763
22 2PT9 S4M 1.55763
23 5K4W THR 1.55763
24 1ZGS XMM 1.566
25 6EL3 NAP 1.5748
26 4YT4 FE9 1.6
27 3TLJ SAH 1.60858
28 1GV0 NAD 1.6129
29 4HXY NDP 1.65289
30 4MIG G3F 1.65289
31 5N6C NAD 1.66667
32 1SO2 666 1.66667
33 1OBB NAD 1.66667
34 3SSO SAH 1.67064
35 1X7D NAD 1.71429
36 5THY SAH 1.7284
37 3JQA NAP 1.73611
38 5JDC NAP 1.73611
39 3BMO NAP 1.73611
40 5JCJ NAP 1.73611
41 3JQF NAP 1.73611
42 5K6A NAP 1.73611
43 3BMQ NAP 1.73611
44 5JDI NAP 1.73611
45 4CLO NAP 1.73611
46 3BMN NAP 1.73611
47 3JQ7 NAP 1.73611
48 4CM4 NAP 1.73611
49 3JQ9 NAP 1.73611
50 4CLR NAP 1.73611
51 4M37 SAH 1.74927
52 2I7C AAT 1.76678
53 4MP8 MLI 1.76991
54 4MP8 NAD 1.76991
55 3G5S FAD 1.80587
56 3NJ4 NAD 1.83908
57 1X87 NAD 1.8595
58 5J7X FAD 1.8595
59 4B63 NAP 1.8595
60 4B63 FAD 1.8595
61 4B63 ORN 1.8595
62 5JJR SAH 1.8595
63 5D4V SAH 1.86567
64 2WD7 NAP 1.86567
65 1GUZ NAD 1.93548
66 3CIF NAD 1.94986
67 3CIF G3H 1.94986
68 1HKU NAD 1.95531
69 1O6Z NAD 1.9802
70 1W8D NAP 1.98676
71 1W73 NAP 1.98676
72 1W6U NAP 1.98676
73 4NBU NAI 2
74 1O5I NAD 2.00803
75 3LST SAH 2.01149
76 5KOK SAH 2.01511
77 3GRU AMP 2.0339
78 1LLU NAD 2.04678
79 5A1T NAI 2.05279
80 5A1T OXM 2.05279
81 3O03 NAP 2.06186
82 3IHG FAD 2.06612
83 4K5S FAD 2.06612
84 4Z24 FAD 2.06612
85 1MO9 FAD 2.06612
86 1MO9 KPC 2.06612
87 5WP5 SAH 2.06612
88 3Q9T FAY 2.06612
89 5WP4 SAH 2.06612
90 6H3O FAD 2.06612
91 2QA1 FAD 2.06612
92 4K5S PM0 2.06612
93 5JWC FAD 2.06612
94 2AQJ TRP 2.06612
95 2AQJ FAD 2.06612
96 4XB2 NDP 2.08955
97 4XB2 HSE 2.08955
98 1L1E SAH 2.09059
99 2D2I NAP 2.10526
100 4DCM SAM 2.13333
101 2XVF FAD 2.15517
102 1OMO NAD 2.17391
103 5MPT SAH 2.17391
104 1PJS NAD 2.18818
105 1P77 ATR 2.20588
106 5TC4 NAD 2.21519
107 5X62 SAH 2.21675
108 6C4T NA7 2.22222
109 1PNO NAP 2.22222
110 1EBF NAD 2.23464
111 5UAO FAD 2.27273
112 1BZL FAD 2.27273
113 1BZL GCG 2.27273
114 3GDN HBX 2.27273
115 3GDN FAD 2.27273
116 5X68 FAD 2.27273
117 5EJ2 NAD 2.27273
118 3MAG SAH 2.28013
119 1U1I NAD 2.29592
120 3ZYR NAG NAG BMA MAN MAN NAG NAG 2.29885
121 3TWO NDP 2.29885
122 1Y8Q ATP 2.31214
123 6AA8 NAD 2.31788
124 5OLK DTP 2.32558
125 5Y77 FAD 2.32558
126 3MCT SAH 2.3569
127 3B20 NAD 2.35988
128 3B1J NAD 2.35988
129 3V1Y NAD 2.37389
130 5MZI FAD 2.38612
131 5MZI FYK 2.38612
132 4RQU NAD 2.4
133 2CFC NAD 2.4
134 4YAG NAI 2.42215
135 4RDH AMP 2.43056
136 4RDI ATP 2.43056
137 3W54 RNB 2.43161
138 2CUN 3PG 2.43902
139 1E5Q NDP 2.44444
140 3TKY SAH 2.44565
141 4LWP SAH 2.44565
142 1GR0 NAD 2.45232
143 5THZ SAH 2.46914
144 4EIP K2C 2.47934
145 3X0D SAH 2.47934
146 2OG7 AHB 2.47934
147 4KVL PLM 2.47934
148 1GPE FAD 2.47934
149 5OC1 FAD 2.47934
150 1GQ2 NAP 2.47934
151 4EIP FAD 2.47934
152 4YMH SAH 2.5
153 4NBT NAD 2.5
154 1NW5 SAM 2.50784
155 2HNK SAH 2.51046
156 1PL6 NAD 2.52809
157 1PL6 572 2.52809
158 4D79 ATP 2.53623
159 5ZYN FAD 2.54777
160 2B56 U5P 2.5641
161 5H81 NAP 2.57069
162 5THQ NDP 2.57353
163 4UCC ZKW 2.57511
164 1NYT NAP 2.58303
165 2F7A BEZ 2.58621
166 2XVE FAD 2.58621
167 3V1U NAD 2.5974
168 2PX8 SAH 2.60223
169 2OOR NAD 2.60417
170 1L7E NAI 2.60417
171 1F8G NAD 2.60417
172 1NM5 NAD 2.60417
173 3RFV 15L 2.62172
174 3RFV NAI 2.62172
175 4I90 CHT 2.64026
176 2VHW NAI 2.65252
177 5G6U TRP 2.68199
178 5OJL TXP 2.68456
179 5A2Z GTP 2.68595
180 3QVP FAD 2.68595
181 4YNU LGC 2.68595
182 4YNU FAD 2.68595
183 2WET FAD 2.68595
184 6FDF SAH 2.69461
185 4JK3 NAD 2.7027
186 4J4H 1J1 2.7027
187 3LZW FAD 2.71084
188 3LZW NAP 2.71084
189 2HQM FAD 2.71399
190 5EOW FAD 2.71605
191 3TN7 NJP 2.72374
192 1KYZ SAH 2.73973
193 3MB5 SAM 2.7451
194 3DXY SAM 2.75229
195 2CVQ NDP 2.75229
196 6FHO FAD 2.75689
197 2OG2 MLI 2.78552
198 3DAG FEG 2.7933
199 1ZGA SAH 2.80112
200 3LKZ SFG 2.80374
201 1A5Z NAD 2.82132
202 2JJQ SAH 2.82353
203 4E13 NAD 2.82686
204 1OXV ANP 2.83286
205 5EES NAP 2.83401
206 2JAP NDP 2.83401
207 2JAH NDP 2.83401
208 2DT5 NAD 2.8436
209 1LDN NAD 2.8481
210 2BD0 NAP 2.86885
211 1IM8 SAI 2.86885
212 4MOP 2H5 2.89256
213 5OSW DIU 2.89256
214 1O0S NAI 2.89256
215 1EQ2 NAP 2.90323
216 4JJF FE9 2.90698
217 4JJF N2I 2.90698
218 2IXB NAD 2.92793
219 5BVA FAD 2.93399
220 6F7L FAD 2.94118
221 1DSS NAD 3.003
222 1J0X NAD 3.01205
223 1KOL NAD 3.01508
224 1H5Q NAP 3.01887
225 6GAS FAD 3.02115
226 4NEC SAH 3.0303
227 5GT9 NAP 3.04183
228 3AB1 FAD 3.05556
229 5Z75 NAD 3.0581
230 1ZBQ NAD 3.0581
231 4YKG NAD 3.07102
232 4YKG FAD 3.07102
233 5LD5 NAD 3.07263
234 2CDU ADP 3.09735
235 2CDU FAD 3.09735
236 1BXK NAD 3.09859
237 2NVK NAP 3.09917
238 6F97 FAD 3.09917
239 5ERG SAM 3.09917
240 5MQ6 NDP 3.09917
241 2NVK FAD 3.09917
242 3E1T FAD 3.09917
243 1PN0 FAD 3.09917
244 1PN0 IPH 3.09917
245 1Z45 NAD 3.09917
246 5JCM NAD 3.10421
247 5JCM FAD 3.10421
248 5JCM ISD 3.10421
249 1WP4 NDP 3.11419
250 2CVZ NDP 3.11419
251 2A92 NAI 3.11526
252 5J60 FAD 3.125
253 1FP2 SAH 3.125
254 2RGO FAD 3.13015
255 1EZ4 NAD 3.14465
256 2O4C NAD 3.15789
257 4TM3 FAD 3.16027
258 6C8R SAH 3.16623
259 1O5O U5P 3.16742
260 5YU3 PRO 3.19767
261 5YU3 NAD 3.19767
262 2F5X ASP 3.20513
263 2EWM NAD 3.21285
264 3WLE NAD 3.22581
265 3SJU NDP 3.22581
266 1RJW ETF 3.24484
267 6F5W KG1 3.25203
268 4Y9D NAI 3.27869
269 4MDH NAD 3.29341
270 4HA6 FAD 3.30579
271 5FJN BE2 3.30579
272 5FJN FAD 3.30579
273 3B9Q MLI 3.31126
274 1N2X SAM 3.32226
275 2FAV APR 3.33333
276 3BXO SAM 3.34728
277 4EUE NAI 3.34928
278 4ZGS NAD 3.36788
279 1BW9 NAD 3.37079
280 2GDZ NAD 3.37079
281 3GMB FAD 3.37349
282 3KLJ FAD 3.37662
283 1C1X NAD 3.38028
284 2DC1 NAD 3.38983
285 5MGZ SAH 3.38983
286 5N0J FAD 3.4188
287 3GFB NAD 3.42857
288 4M52 FAD 3.43348
289 4M52 M52 3.43348
290 1LTH NAD 3.44828
291 2A8X FAD 3.44828
292 1GZ6 NAI 3.44828
293 3H2B SAH 3.44828
294 2DFV NAD 3.45821
295 1CDO NAD 3.47594
296 1D1T NAD 3.48525
297 2EG5 SAH 3.49462
298 4D7E FAD 3.4965
299 1Q9I TEO 3.50263
300 1Q9I FAD 3.50263
301 2RGH FAD 3.50263
302 2BRY FAD 3.5124
303 1NAA ABL 3.5124
304 1NAA 6FA 3.5124
305 3S1S SAH 3.5124
306 3CGB FAD 3.5124
307 4TXI FAD 3.5124
308 5U8U FAD 3.5343
309 3CGD FAD 3.54167
310 3CGD NAD 3.54167
311 3CGD COA 3.54167
312 4D3F NAP 3.54839
313 2ZFI ADP 3.55191
314 5BUK FAD 3.55556
315 2Q46 NAP 3.55731
316 4L8V NAP 3.56083
317 5FUB SAH 3.56083
318 3LAD FAD 3.57143
319 3AXB PRO 3.57143
320 3AXB FAD 3.57143
321 2F1K NAP 3.58423
322 4X9M FAD 3.58852
323 4Z0H NAD 3.59281
324 4PLG OXM 3.59281
325 4PLG NAI 3.59281
326 5GWT NAD 3.59712
327 4AZW SAM 3.60934
328 3SIG AR6 3.61011
329 4O0L NDP 3.63636
330 1KYQ NAD 3.64964
331 3A4T SFG 3.64964
332 6A3J NAI 3.65854
333 1C3V NDP 3.67347
334 2YVF NAD 3.67647
335 2YVF FAD 3.67647
336 3FPZ AHZ 3.68098
337 3JWH SAH 3.68664
338 2Q7V FAD 3.69231
339 5HXI FAD 3.69393
340 5HXI 5HN 3.69393
341 6FBZ MGP 3.7037
342 4ITU NAI 3.71747
343 1QO8 FAD 3.71901
344 2GMH FAD 3.71901
345 3NB0 G6P 3.71901
346 3W5N RAM 3.71901
347 2D3N GLC GLC GLC 3.71901
348 1VL8 NAP 3.74532
349 1V8B NAD 3.75783
350 1VL0 NAI 3.76712
351 2B4R AES 3.76812
352 2B4R NAD 3.76812
353 1XMY ROL 3.76884
354 5FEU NAP 3.78007
355 3B1F NAD 3.7931
356 1E4I NFG 3.80313
357 1XHC FAD 3.81471
358 4UP3 NDP 3.82166
359 4UP3 FAD 3.82166
360 4NTD FAD 3.82353
361 2CDC XYP 3.82514
362 6AIN FAD 3.82775
363 1IZC PYR 3.83481
364 3A28 NAD 3.87597
365 5TTJ FAD 3.87755
366 4J1Q NDP 3.87931
367 4NTC FAD 3.8806
368 5EVY FAD 3.88128
369 2RAB NAD 3.88769
370 2RAB FAD 3.88769
371 3WMX NAD 3.91061
372 1LVL NAD 3.92562
373 1WDK NAD 3.92562
374 1LVL FAD 3.92562
375 6FP4 E1T 3.92562
376 6FP4 FAD 3.92562
377 5BRT CH9 3.92562
378 5BRT FAD 3.92562
379 2ZXI FAD 3.92562
380 2DKH 3HB 3.92562
381 2FR1 NDP 3.92562
382 2DKH FAD 3.92562
383 1VKO NAD 3.92562
384 1M2W NAD 3.92562
385 4KRI SAH 3.9261
386 5JE8 NAD 3.97351
387 5MIT FAD 3.97554
388 5MIT NAP 3.97554
389 5F8F SFG 3.97878
390 4POO SAM 4
391 4XBA GMP 4
392 6C4N NAP 4.00891
393 4FWE FAD 4.0201
394 3VSE SAH 4.0201
395 2Y6Q I7T 4.0201
396 2Y6Q FAD 4.0201
397 3ZNN FAD 4.03458
398 3ZNN 4WL 4.03458
399 3WGT FAD 4.03458
400 3WGT QSC 4.03458
401 4JBI NDP 4.05405
402 1JQ3 AAT 4.05405
403 5ZI2 NAD 4.05797
404 5ZI2 ADP 4.05797
405 3FUU ADN 4.05904
406 1YKJ PHB 4.06091
407 1YKJ FAD 4.06091
408 3CTY FAD 4.07523
409 6GNC FAD 4.08163
410 1G55 SAH 4.08163
411 3OA2 NAD 4.08805
412 1HDR NAD 4.09836
413 3T7S SAM 4.10448
414 1TDF NAP 4.11392
415 1TDF FAD 4.11392
416 6D6Y SAH 4.13223
417 3LXD FAD 4.13223
418 5W7K SAH 4.16667
419 6GNA FAD 4.16667
420 4GKV NAD 4.16667
421 5DUS APR 4.16667
422 1RPN NDP 4.1791
423 2JL1 NAP 4.18118
424 1LUA NAP 4.18118
425 1SQF SAM 4.1958
426 5C9P FUC 4.19948
427 5KOX FAD 4.20168
428 5KOX RFP 4.20168
429 1U7T NAD 4.21456
430 4XFR CIT 4.21546
431 6C4M NAP 4.21941
432 3WFD AXO 4.22535
433 2VYN NAD 4.22961
434 5NMX NAP 4.23529
435 5NMX FAD 4.23529
436 1GAD NAD 4.24242
437 1XCL SAH 4.25532
438 1FK8 NAD 4.28016
439 5FFF NAP 4.28016
440 1YJQ NAP 4.29043
441 1GEG NAD 4.29688
442 1FP1 SAH 4.30108
443 5N2I NAP 4.31034
444 4QEK GLC 4.31894
445 3UCL NAP 4.33884
446 3UCL FAD 4.33884
447 3UCL CYH 4.33884
448 4RSL FAD 4.33884
449 1KJ8 GAR 4.34783
450 6F3M NAD 4.34783
451 1JJV ATP 4.36893
452 2C7G FAD 4.38596
453 2C7G ODP 4.38596
454 1C0I FAD 4.40771
455 1C0I BE2 4.40771
456 6F9Q NAD 4.41176
457 4OPC PGT 4.41501
458 4OPC FDA 4.41501
459 1DL5 SAH 4.4164
460 1SC6 NAD 4.45545
461 2YX1 SFG 4.46429
462 5OCM NAP 4.46735
463 1RJD SAM 4.49102
464 4KOA NDP 4.5045
465 1EDO NAP 4.5082
466 3W68 4PT 4.51128
467 1D4D FAD 4.54545
468 1EXF GLY 4.54545
469 6ER9 FAD 4.54545
470 6ER9 NAP 4.54545
471 5EB4 FAD 4.54545
472 1DJN ADP 4.54545
473 5LX9 OLB 4.56026
474 1ZEM NAD 4.58015
475 2O07 MTA 4.60526
476 2O07 SPD 4.60526
477 1Z6Z NAP 4.60993
478 1ORR NAD 4.61095
479 1ELI PYC 4.62725
480 4EMI NAD 4.63415
481 4EMI FAD 4.63415
482 5Z20 NAI 4.63768
483 2PWY SAH 4.65116
484 2PK3 A2R 4.6729
485 1SAY PYR 4.70914
486 4FN4 NAD 4.72441
487 3ITJ CIT 4.73373
488 3ITJ FAD 4.73373
489 5Y8L NAD 4.74576
490 5Y8L HUI 4.74576
491 1CF2 NAP 4.74777
492 4C3Y ANB 4.75207
493 1COY FAD 4.75207
494 4C3Y FAD 4.75207
495 1COY AND 4.75207
496 5AHO TLA 4.7619
497 3L4S NAD 4.7619
498 3L4S 3PG 4.7619
499 4R5M NAP 4.78723
500 2D0O ADP 4.8
501 2YY7 NAD 4.80769
502 1V59 NAD 4.81172
503 1V59 FAD 4.81172
504 5NUF NAD 4.81928
505 5NUE NAD 4.81928
506 2XYQ SAH 4.82759
507 4PLT NAI 4.83384
508 4PLT OXM 4.83384
509 6BQ6 TER 4.83384
510 5NII FAD 4.85437
511 4RZB NFQ 4.85651
512 3GEG NAD 4.8583
513 2VDV SAM 4.87805
514 5TUK FAD 4.90196
515 1O94 ADP 4.92424
516 1NV8 SAM 4.92958
517 1NV8 MEQ 4.92958
518 2V6G NAP 4.94506
519 3LU1 NAD 4.94506
520 1V6A TRE 4.95868
521 4IV9 FAD 4.95868
522 4D04 NAP 4.95868
523 4D04 FAD 4.95868
524 5W7B MYR 4.96454
525 5UAV NDP 4.96894
526 5UAV TFB 4.96894
527 1RYI FAD 4.97382
528 1RYI GOA 4.97382
529 4CQM NAP 4.98084
530 3U4C NDP 4.98221
531 4USQ FAD 4.98615
532 1E1M FAD 5
533 1E1M NAP 5
534 3G2O SAM 5.01672
535 3Q3C NAD 5.01672
536 1P1C SAH 5.02513
537 1VQW FAD 5.03282
538 4NBW NAD 5.05837
539 5OVK NDP 5.07812
540 1Q1R FAD 5.10441
541 5O4J SAH 5.10949
542 5O4J PJL 5.10949
543 5O4J 9KH 5.10949
544 2NXE SAM 5.11811
545 1HDG NAD 5.12048
546 1PZG A3D 5.13595
547 3H8V ATP 5.13699
548 2NPX NAD 5.14541
549 2GV8 NDP 5.14541
550 2GVC FAD 5.14541
551 2NPX FAD 5.14541
552 2GV8 FAD 5.14541
553 4E5N NAD 5.15152
554 2AUY NAG MAN MMA 5.15873
555 2AR6 NAG MAN MAN MAN NAG 5.15873
556 1FL2 FAD 5.16129
557 3VPH NAD 5.16129
558 3VPH OXM 5.16129
559 4AT0 FAD 5.16529
560 1LDM NAD 5.16717
561 4OM8 NAD 5.17799
562 1HYH NAD 5.17799
563 1R37 NAD 5.18732
564 5KVS NAP 5.19481
565 1X14 NAD 5.23691
566 2AWN ADP 5.24934
567 3Q87 SAM 5.29412
568 1H82 FAD 5.29661
569 1H82 GZZ 5.29661
570 1MT1 AG2 5.30973
571 1E3I CXF 5.31915
572 5ZW3 SAH 5.33333
573 4YRY NAD 5.34188
574 4YRY FAD 5.34188
575 1I9G SAM 5.35714
576 3OID NDP 5.42636
577 5K0A FAD 5.45455
578 1E6E FAD 5.46875
579 3ABI NAD 5.47945
580 3T31 FAD 5.49199
581 1UXG NAD 5.50162
582 1UXG FUM 5.50162
583 4J36 1HR 5.54217
584 4J36 FAD 5.54217
585 4YJK URA 5.55556
586 2NU8 COA 5.55556
587 3QWI NAP 5.55556
588 5C1M OLC 5.6
589 4EMJ FAD 5.60748
590 4B4U NAP 5.61056
591 5EZ7 FAD 5.61225
592 3G89 SAM 5.62249
593 5A96 GTP 5.62249
594 4XZ3 COA 5.65217
595 3NKS FAD 5.66038
596 4GNC ASO 5.68562
597 4JDR FAD 5.6962
598 1YQZ FAD 5.70776
599 9LDT NAD 5.72289
600 9LDB NAD 5.72289
601 2ZIF SAM 5.72391
602 5E9W SAH 5.76923
603 5E8J SAH 5.76923
604 4L8F MTX 5.76923
605 1B8U NAD 5.77508
606 3ICT ADP 5.78512
607 3ICS ADP 5.78512
608 1REO FAD 5.78512
609 1UAY ADN 5.78512
610 3ICT FAD 5.78512
611 3ICR FAD 5.78512
612 3ICS FAD 5.78512
613 5VN0 NAI 5.78512
614 5VN0 FAD 5.78512
615 2EJU SAH 5.82011
616 5AYV NAP 5.82524
617 4YSX FAD 5.85106
618 1P0F NAP 5.89812
619 3C3Y SAH 5.90717
620 5XNC MTA 5.92992
621 5GSN NAP 5.96026
622 5GSN FAD 5.96026
623 5GSN MMZ 5.96026
624 6BVI EC4 5.98802
625 6BVL EBY 5.98802
626 6BVJ EAS 5.98802
627 6BVK EAV 5.98802
628 6BVM EBV 5.98802
629 1YY5 FAD 5.99174
630 1RSG FAD 5.99174
631 2R4J FAD 5.99174
632 2R4J 13P 5.99174
633 1UP7 NAD 5.9952
634 1ZK7 FAD 5.99572
635 1FUR MLT 5.99572
636 4KRG SAH 6.00858
637 2XVM SAH 6.03015
638 2PV7 NAD 6.04027
639 3H9E NAD 6.06936
640 3NUG NAD 6.07287
641 3G5N PB2 6.09244
642 4USR FAD 6.09418
643 2Q0L NAP 6.10932
644 2Q0L FAD 6.10932
645 1QAN SAH 6.14754
646 5KMS FAD 6.17284
647 5KMS NAD 6.17284
648 4JNA FAD 6.17647
649 2HK9 ATR 6.18182
650 2HK9 NAP 6.18182
651 2JHP SAH 6.19835
652 5JGL SAM 6.22837
653 2HMT NAI 6.25
654 3K7M FAD 6.2645
655 4CJX NAP 6.26959
656 3NYC FAD 6.29921
657 3NYC IAR 6.29921
658 5DN9 NAD 6.31868
659 2IZ1 ATR 6.32911
660 3GU3 SAH 6.33803
661 5I39 FAD 6.37255
662 3LCC SAH 6.38298
663 4DPL NAP 6.40669
664 1NVM NAD 6.41026
665 3WV8 ATP 6.42202
666 5N18 8HZ 6.42202
667 4YCA NDP 6.46258
668 2AG8 NAP 6.46388
669 5KVA SAM 6.47482
670 3RKR NAP 6.48855
671 2AOT SAH 6.50685
672 4XQC 13D 6.52632
673 4XQC NAD 6.52632
674 5E5U MLI 6.53266
675 3OZ2 FAD 6.54912
676 3WBF NAP 6.55738
677 3KB6 NAD 6.58683
678 2IID PHE 6.61157
679 2IID FAD 6.61157
680 2Z3Y F2N 6.61157
681 3AYI HCI 6.61157
682 3AYI FAD 6.61157
683 5YB7 FAD 6.61157
684 5YB7 ORN 6.61157
685 1PS9 FAD 6.61157
686 1GTE FAD 6.61157
687 1PS9 NAP 6.61157
688 5YF1 SFG 6.62983
689 1GET NAP 6.66667
690 1GET FAD 6.66667
691 1WG8 SAM 6.66667
692 3DUW SAH 6.72646
693 1XG5 NAP 6.81004
694 2VVL FAD 6.81818
695 2VVM FAD 6.81818
696 5TS5 FAD 6.81818
697 2WPF WPF 6.81818
698 2WPF FAD 6.81818
699 4REP FAD 6.86869
700 3QFA FAD 6.89655
701 2Q1W NAD 6.90691
702 2ZFU SAH 6.97674
703 3GGO NAI 7.00637
704 3GGO ENO 7.00637
705 1BXG NAD 7.02247
706 4AP3 NAP 7.02479
707 4AP3 FAD 7.02479
708 4YAC NAI 7.07071
709 2YLD CMO 7.08661
710 2G5C NAD 7.11744
711 1N8V BDD 7.14286
712 3K5I AIR 7.19603
713 1VDC FAD 7.20721
714 3UOY NAP 7.2314
715 3UOY FAD 7.2314
716 1VJT NAD 7.24638
717 3QV1 NAD 7.31707
718 1SOW NAD 7.31707
719 2BOS GLA GAL GLC 7.35294
720 2BOS GLA GAL GLC NBU 7.35294
721 5BJX UDP 7.37705
722 5BJX NAD 7.37705
723 4M73 SAH 7.4184
724 4M73 M72 7.4184
725 3FG2 FAD 7.42574
726 3F8D FAD 7.43034
727 1KNR FAD 7.43802
728 4BV6 FAD 7.43802
729 3VYW SAM 7.46753
730 3GDH SAH 7.46888
731 1IY8 NAD 7.49064
732 5L95 AMP 7.5
733 3SJ7 NDP 7.53968
734 3NY4 SMX 7.54717
735 5TWB FAD 7.55814
736 5HSA FAS 7.64463
737 1UZN NAP 7.69231
738 3EWR APR 7.7381
739 3BBH SFG 7.80488
740 1J49 NAD 7.80781
741 1F8F NAD 7.81671
742 5NA1 FAD 7.84314
743 5J5Z FAD 7.85124
744 1FEC FAD 7.85124
745 3GD4 NAD 7.85124
746 3GD4 FAD 7.85124
747 5NM7 GLY 7.89474
748 4J56 FAD 7.89474
749 4F4S EFO 7.89474
750 5F5N NAD 7.95848
751 5KKA 6V0 8.01282
752 2F5Z FAD 8.01688
753 5TUF FAD 8.06846
754 5TUF TDC 8.06846
755 2GAG FAD 8.08081
756 2GAG FOA 8.08081
757 3AD8 NAD 8.08081
758 2GAG NAD 8.08081
759 3A27 SAM 8.08823
760 2E5V FAD 8.26271
761 3NTD FAD 8.26446
762 5GZ6 NDP 8.28221
763 5GZ6 7C3 8.28221
764 1VI2 NAD 8.33333
765 5Z21 NAI 8.37989
766 5DNK SAH 8.47107
767 3GCZ SAM 8.51064
768 4V2O CLQ 8.53659
769 4OBW SAM 8.56031
770 1LSS NAD 8.57143
771 3OJO NAD 8.58469
772 6GAR FAD 8.59599
773 1RM4 NDP 8.60534
774 1NPD NAD 8.68056
775 3L9W AMP 8.71671
776 3L9W GSH 8.71671
777 2B9W FAD 8.72641
778 3EGI ADP 8.73786
779 4J8T DOG 8.75912
780 5N5D SAM 8.84956
781 3S5W NAP 8.85529
782 3S5W FAD 8.85529
783 1Q0S SAH 8.88031
784 3NT6 FAD 8.8843
785 3NTA FAD 8.8843
786 5K9B FMN 8.88889
787 4BJZ P3A 8.96226
788 4BJZ FAD 8.96226
789 2CUL FAD 9.05172
790 5MBX SP5 9.09091
791 5MBX FAD 9.09091
792 2YVJ NAI 9.17431
793 2YVJ FAD 9.17431
794 6B92 SAH 9.18367
795 5IM3 DTP 9.29752
796 2VT3 ATP 9.30233
797 3CBG SAH 9.48276
798 1J5P NAD 9.48617
799 3TKA SAM 9.51009
800 4KIB SAH 9.52381
801 1E3W NAD 9.57854
802 1LOF MAN BMA NAG NAG MAN NAG GAL GAL 9.61539
803 1E6W NAD 9.61539
804 5FTW SAH 9.76562
805 5XVH NAP 9.80392
806 5JCA NDP 9.85915
807 5JCA FAD 9.85915
808 1EJ0 SAM 10
809 1OW4 2AN 10.0775
810 5ZZ6 ADP 10.0962
811 5ZZ6 NAD 10.0962
812 2OFW ADX 10.0962
813 5L4L NAP 10.1974
814 1D4O NAP 10.3261
815 5C2N NAG 10.4167
816 1FWV SGA MAG FUC 10.4478
817 4URF NAD 10.4839
818 4TQG NDP 10.5263
819 4Q0A 4OA 10.596
820 6GFK SAH 10.757
821 5EE5 GTP 10.7981
822 4II2 ATP 10.8434
823 2HJR APR 10.9756
824 4CNK FAD 10.9974
825 4ZCC FAD 11.0119
826 4ZCC NAI 11.0119
827 3SQP FAD 11.0879
828 5EIN NAP 11.1111
829 2PXX SAH 11.1628
830 5CAE COA 11.1821
831 4FZV SAM 11.2971
832 1KEV NDP 11.396
833 4RF2 NAP 11.3971
834 2GUE NAG 11.4754
835 5W7M SAH 11.5385
836 2FKA BEF 11.6279
837 3QJ4 FAD 11.6959
838 2PEZ DAT 11.7318
839 2BGM NAJ 11.7769
840 1GY8 NAD 11.8388
841 3RET SAL 11.8812
842 3RET PYR 11.8812
843 1R18 SAH 11.8943
844 5UR0 NAD 12.0344
845 3OFK SAH 12.037
846 2IVD FAD 12.1339
847 2P39 SCR 12.2581
848 1G60 SAM 12.3077
849 1CER NAD 12.3867
850 5HJM MTA 12.5
851 1H2B NAJ 12.5348
852 3DMH SAM 12.8609
853 2YG3 FAD 13.0243
854 3H5N ATP 13.0312
855 4BVA NDP 13.1343
856 3FZG SAM 13.5
857 1JG3 ADN 13.617
858 2RGJ FAD 13.6816
859 4QTU SAM 13.9423
860 1RP0 AHZ 14.0845
861 5YEC ATP 14.2857
862 1UPT GTP 15
863 3RNM FAD 15.5172
864 4A6D SAM 15.5807
865 1VM6 NAD 16.2281
866 1PHP ADP 16.2437
867 1WVG APR 16.4345
868 1ZQ9 SAM 17.5439
869 5BW4 SAM 17.9775
870 1XTP SAI 18.1102
871 5ZBC FAD 18.847
872 2DPM SAM 19.0141
873 4YMU ATP 19.0909
874 1JNR FAD 19.3333
875 6FC1 MGP 20.3125
876 5G3U ITW 20.8038
877 5G3U FDA 20.8038
878 5ODQ FAD 21.7391
879 5Z84 CHD 22.0339
880 5ZCO CHD 22.0339
881 5W97 CHD 22.0339
882 4GQB 0XU 22.7273
883 2JB2 PHE 23.3471
884 2JB2 FAD 23.3471
885 1NVT NAP 23.6934
886 4M38 SAH 23.8095
887 4GUT FAD 24.1935
888 4GUS FAD 24.1935
889 4HSU FAD 24.1935
890 5FA5 MTA 25
891 3X0V FAD 25.8264
892 6F5Z SAH 26.2295
Pocket No.: 2; Query (leader) PDB : 4DSG; Ligand: UDP; Similar sites found with APoc: 892
This union binding pocket(no: 2) in the query (biounit: 4dsg.bio2) has 59 residues
No: Leader PDB Ligand Sequence Similarity
1 1TUK PGM None
2 1GYY FHC None
3 5WGR FAD 1.03306
4 1MV8 NAD 1.14679
5 1MUU NAD 1.14679
6 3G4G D71 1.18765
7 3HWW AKG 1.23967
8 1P31 EPU 1.26316
9 1P3D UMA 1.26316
10 4DMG SAM 1.27226
11 3G58 988 1.31234
12 3P2E SAH 1.33333
13 5OFW 9TW 1.34529
14 4C4A SAH 1.44628
15 5CX8 TG6 1.4553
16 3PT9 SAH 1.48912
17 4ZNO SUC 1.49254
18 6CEP NAD 1.49701
19 6CEP OXM 1.49701
20 5N53 8NB 1.53846
21 5K4W NAI 1.55763
22 2PT9 S4M 1.55763
23 5K4W THR 1.55763
24 1ZGS XMM 1.566
25 6EL3 NAP 1.5748
26 4YT4 FE9 1.6
27 3TLJ SAH 1.60858
28 1GV0 NAD 1.6129
29 4HXY NDP 1.65289
30 4MIG G3F 1.65289
31 5N6C NAD 1.66667
32 1SO2 666 1.66667
33 1OBB NAD 1.66667
34 3SSO SAH 1.67064
35 1X7D NAD 1.71429
36 5THY SAH 1.7284
37 3JQA NAP 1.73611
38 5JDC NAP 1.73611
39 3BMO NAP 1.73611
40 5JCJ NAP 1.73611
41 3JQF NAP 1.73611
42 5K6A NAP 1.73611
43 3BMQ NAP 1.73611
44 5JDI NAP 1.73611
45 4CLO NAP 1.73611