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Receptor
PDB id Resolution Class Description Source Keywords
4EIP 2.33 Å NON-ENZYME: OTHER NATIVE AND K252C BOUND REBC-10X LECHEVALIERIA AEROCOLONIGENES FLAVIN ADENINE DINUCLEOTIDE K252C MONOOXYGENASE INDOLOCAROXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
Ref.: AN UNUSUAL ROLE FOR A MOBILE FLAVIN IN STAC-LIKE INDOLOCARBAZOLE BIOSYNTHETIC ENZYMES. CHEM.BIOL. V. 19 855 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FAD A:602;
B:600;
Valid;
Valid;
none;
none;
Kd = 20 uM
785.55 C27 H33 N9 O15 P2 Cc1cc...
K2C A:601;
Valid;
none;
submit data
311.337 C20 H13 N3 O c1ccc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4EIP 2.33 Å NON-ENZYME: OTHER NATIVE AND K252C BOUND REBC-10X LECHEVALIERIA AEROCOLONIGENES FLAVIN ADENINE DINUCLEOTIDE K252C MONOOXYGENASE INDOLOCAROXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
Ref.: AN UNUSUAL ROLE FOR A MOBILE FLAVIN IN STAC-LIKE INDOLOCARBAZOLE BIOSYNTHETIC ENZYMES. CHEM.BIOL. V. 19 855 2012
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 2R0C - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 2R0G - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
3 2R0P - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
4 4EIP Kd = 20 uM FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 2R0C - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 2R0G - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
3 2R0P - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
4 4EIP Kd = 20 uM FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 2R0C - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 2R0G - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
3 2R0P - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
4 4EIP Kd = 20 uM FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FAD; Similar ligands found: 128
No: Ligand ECFP6 Tc MDL keys Tc
1 FAD 1 1
2 FAS 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 FAE 0.751773 0.987654
7 SFD 0.651007 0.860215
8 FDA 0.641892 0.906977
9 FNK 0.602564 0.876405
10 62F 0.572327 0.939024
11 F2N 0.566265 0.886364
12 FMN 0.543307 0.876543
13 FA9 0.526316 0.939759
14 6YU 0.516304 0.860215
15 P6G FDA 0.511628 0.908046
16 FAD NBT 0.508876 0.83871
17 A2D 0.504065 0.875
18 P5F 0.491329 0.941176
19 FAD CNX 0.488506 0.8125
20 AR6 0.488372 0.851852
21 APR 0.488372 0.851852
22 AGS 0.484615 0.811765
23 SAP 0.484615 0.811765
24 M33 0.484375 0.864198
25 BA3 0.484127 0.875
26 HEJ 0.48062 0.851852
27 ATP 0.48062 0.851852
28 ADP 0.480315 0.851852
29 B4P 0.480315 0.875
30 AP5 0.480315 0.875
31 ANP 0.477273 0.831325
32 AQP 0.476923 0.851852
33 5FA 0.476923 0.851852
34 48N 0.469388 0.902439
35 OAD 0.467626 0.876543
36 9X8 0.467626 0.833333
37 FAD NBA 0.467033 0.793814
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AT4 0.465116 0.821429
41 AD9 0.462121 0.831325
42 3OD 0.460993 0.876543
43 RBF 0.460938 0.790123
44 FB0 0.460606 0.835165
45 139 0.460526 0.858824
46 AP0 0.46 0.835294
47 A22 0.459854 0.864198
48 ACP 0.458015 0.853659
49 8QN 0.456522 0.864198
50 PRX 0.454545 0.831325
51 A3R 0.453237 0.86747
52 A1R 0.453237 0.86747
53 G3A 0.452055 0.902439
54 T5A 0.45098 0.872093
55 G5P 0.44898 0.902439
56 ATF 0.448529 0.821429
57 50T 0.44697 0.819277
58 6YZ 0.445255 0.853659
59 ACQ 0.444444 0.853659
60 CNV FAD 0.443182 0.917647
61 ADQ 0.442857 0.853659
62 PAJ 0.442857 0.847059
63 5AL 0.441176 0.864198
64 ADX 0.439394 0.775281
65 CA0 0.439394 0.853659
66 A4P 0.437909 0.831461
67 25L 0.4375 0.864198
68 P33 FDA 0.436464 0.817204
69 5SV 0.435714 0.793103
70 OMR 0.434211 0.818182
71 TXE 0.434211 0.890244
72 ABM 0.434109 0.829268
73 A 0.433071 0.82716
74 AMP 0.433071 0.82716
75 4AD 0.432624 0.855422
76 ADJ 0.432258 0.818182
77 B5M 0.431507 0.878049
78 B5Y 0.431507 0.878049
79 BIS 0.430556 0.802326
80 SRA 0.429688 0.788235
81 AFH 0.42953 0.825581
82 NXX 0.427632 0.865854
83 DND 0.427632 0.865854
84 UP5 0.427632 0.878049
85 6V0 0.427632 0.857143
86 TXD 0.427632 0.890244
87 DQV 0.426667 0.8875
88 SRP 0.42446 0.843373
89 PR8 0.423611 0.837209
90 T99 0.423358 0.821429
91 TAT 0.423358 0.821429
92 AMO 0.422535 0.865854
93 TXA 0.42069 0.865854
94 FYA 0.42069 0.864198
95 PTJ 0.42069 0.835294
96 CNA 0.420382 0.865854
97 00A 0.41958 0.823529
98 AHX 0.41958 0.835294
99 MAP 0.41844 0.811765
100 NAI 0.418301 0.845238
101 AU1 0.41791 0.831325
102 A12 0.416667 0.843373
103 AP2 0.416667 0.843373
104 25A 0.415493 0.851852
105 9ZA 0.415493 0.845238
106 9ZD 0.415493 0.845238
107 COD 0.415094 0.842697
108 4TC 0.412903 0.879518
109 APC 0.411765 0.843373
110 ME8 0.410959 0.806818
111 1ZZ 0.410959 0.806818
112 NB8 0.410959 0.835294
113 4UW 0.409091 0.825581
114 NAX 0.409091 0.837209
115 F2R 0.408805 0.850575
116 RBY 0.408759 0.843373
117 ADV 0.408759 0.843373
118 P1H 0.405882 0.818182
119 OOB 0.405594 0.864198
120 LAD 0.40411 0.825581
121 A A 0.40411 0.829268
122 UPA 0.403846 0.86747
123 4UU 0.401316 0.833333
124 GA7 0.401316 0.865854
125 A3D 0.401235 0.876543
126 80F 0.401235 0.808989
127 XAH 0.4 0.806818
128 DLL 0.4 0.864198
Ligand no: 2; Ligand: K2C; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 K2C 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4EIP; Ligand: K2C; Similar sites found with APoc: 518
This union binding pocket(no: 1) in the query (biounit: 4eip.bio1) has 47 residues
No: Leader PDB Ligand Sequence Similarity
1 4KVL PLM 1.0929
2 1GQ2 NAP 1.27505
3 1GZ4 ATP 1.27505
4 4Z24 FAD 1.27505
5 4RQU NAD 1.33333
6 3MCT SAH 1.3468
7 3ICS ADP 1.45719
8 3ICT ADP 1.45719
9 3ICS FAD 1.45719
10 3ICR FAD 1.45719
11 3ICT FAD 1.45719
12 1A5Z NAD 1.5674
13 4RSL FAD 1.57303
14 1UXG NAD 1.61812
15 1UXG FUM 1.61812
16 1O6Z NAD 1.65016
17 1RSG FAD 1.74419
18 1YY5 FAD 1.75439
19 4ZCC NAI 1.78571
20 4ZCC FAD 1.78571
21 1DSS NAD 1.8018
22 3G5S FAD 1.80587
23 2RGH FAD 1.82149
24 4D7E FAD 1.8648
25 1MO9 KPC 1.91205
26 1MO9 FAD 1.91205
27 5VN0 FAD 1.9305
28 5VN0 NAI 1.9305
29 5AYV NAP 1.94175
30 1HYH NAD 1.94175
31 5AYV KPL 1.94175
32 1COY AND 1.97239
33 1COY FAD 1.97239
34 1YS4 NAP 1.9774
35 1YJQ NAP 1.9802
36 5GSN NAP 1.98676
37 5GSN FAD 1.98676
38 5GSN MMZ 1.98676
39 1X87 NAD 1.99637
40 1J0X NAD 2.10843
41 2VHW NAI 2.12202
42 2WET FAD 2.15264
43 2XVE FAD 2.15517
44 3AYI HCI 2.21914
45 3AYI FAD 2.21914
46 5TP0 BRN 2.23214
47 5JWC FAD 2.30326
48 2RGO FAD 2.30643
49 3KLJ FAD 2.33766
50 4NTD FAD 2.35294
51 6ER9 FAD 2.36794
52 6ER9 NAP 2.36794
53 1F8G NAD 2.36794
54 1E1M FAD 2.3913
55 1E1M NAP 2.3913
56 5UAO FAD 2.40296
57 9LDT NAD 2.40964
58 9LDB NAD 2.40964
59 4ZVV NAD 2.40964
60 4ZVV GN0 2.40964
61 1D1T NAD 2.41287
62 1GAD NAD 2.42424
63 4DSG FAD 2.47934
64 4DSG UDP 2.47934
65 2OG2 MLI 2.50696
66 3LAD FAD 2.52101
67 4U8P FDA 2.53411
68 4U8P UDP 2.53411
69 2HK9 ATR 2.54545
70 1GTE FAD 2.55009
71 3K7M FAD 2.5522
72 4CNK FAD 2.55754
73 1KEV NDP 2.5641
74 1WPQ NAD 2.5788
75 2DFV NAD 2.59366
76 4B63 NAP 2.59481
77 4B63 ORN 2.59481
78 4B63 FAD 2.59481
79 2C7G ODP 2.63158
80 2C7G FAD 2.63158
81 1Y1P NMN AMP PO4 2.63158
82 4R5M NAP 2.65957
83 4R5M 4NO 2.65957
84 2NVK NAP 2.66393
85 2NVK FAD 2.66393
86 1RM4 NDP 2.67062
87 4L8V NAP 2.67062
88 3L4S NAD 2.67857
89 3L4S 3PG 2.67857
90 1CER NAD 2.71903
91 1V59 NAD 2.71967
92 1V59 FAD 2.71967
93 3NKS FAD 2.72537
94 2GMH FAD 2.73224
95 5OC1 FAD 2.73224
96 1GPE FAD 2.73224
97 1DLJ NAI 2.73632
98 1YQZ FAD 2.73973
99 2E5V FAD 2.75424
100 1WP4 NDP 2.76817
101 1Q1R FAD 2.78422
102 2AQJ FAD 2.7881
103 2AQJ TRP 2.7881
104 5JCA FAD 2.8169
105 5JCA NDP 2.8169
106 5H81 NAP 2.82776
107 2WPF FAD 2.82828
108 2WPF WPF 2.82828
109 1LJ8 NAD 2.83976
110 1LDN NAD 2.8481
111 4YKG NAD 2.87908
112 4YKG FAD 2.87908
113 5C9P FUC 2.88714
114 4YRY NAD 2.89855
115 4YRY FAD 2.89855
116 5TWB FAD 2.90698
117 2NPX FAD 2.90828
118 2NPX NAD 2.90828
119 4TXI FAD 2.91439
120 1Q9I FAD 2.91439
121 1Q9I TEO 2.91439
122 3FG2 FAD 2.9703
123 3B9Q MLI 2.98013
124 2J5V PCA 2.99728
125 4PLT NAI 3.02115
126 4PLT OXM 3.02115
127 1QMG APX 3.05344
128 5ZI9 FLC 3.07692
129 3LXD FAD 3.09654
130 5OJL TXP 3.09654
131 1NAA ABL 3.09654
132 1DJN ADP 3.09654
133 6H3O FAD 3.09654
134 1NAA 6FA 3.09654
135 2CDU ADP 3.09735
136 2CDU FAD 3.09735
137 3NYC FAD 3.14961
138 3NYC IAR 3.14961
139 5UR0 NAD 3.15186
140 3T31 FAD 3.20366
141 3T31 DCQ 3.20366
142 5MBX SP5 3.21932
143 5MBX FAD 3.21932
144 4XDY NAI 3.25444
145 2VT3 ATP 3.25581
146 3NTD FAD 3.27869
147 4J56 FAD 3.27869
148 6FP4 FAD 3.27869
149 4AP3 FAD 3.27869
150 4AP3 NAP 3.27869
151 3F81 STT 3.27869
152 5J7X FAD 3.27869
153 6FP4 E1T 3.27869
154 5NMX FAD 3.29412
155 5NMX NAP 3.29412
156 1J49 NAD 3.3033
157 5X68 FAD 3.32481
158 1OMO NAD 3.41615
159 5GVR LMR 3.4188
160 5J5Z FAD 3.42742
161 2YVF NAD 3.43137
162 2YVF FAD 3.43137
163 4M52 FAD 3.43348
164 4M52 M52 3.43348
165 1F06 NDP 3.4375
166 2A8X FAD 3.44828
167 3CTY FAD 3.44828
168 2XVF FAD 3.44828
169 5N2I NAP 3.44828
170 4MOP 2H5 3.46084
171 1LVL FAD 3.46084
172 4ISS TAR 3.46084
173 1LVL NAD 3.46084
174 1R6D NAD 3.46084
175 1R6D DAU 3.46084
176 1TDF NAP 3.48101
177 1TDF FAD 3.48101
178 4UP3 FAD 3.50318
179 4UP3 NDP 3.50318
180 3X0V FAD 3.51201
181 5U8U FAD 3.5343
182 2Q0L FAD 3.53698
183 2Q0L NAP 3.53698
184 2B9W FAD 3.53774
185 3CGB FAD 3.54167
186 4D3F NAP 3.54839
187 2G5C NAD 3.55872
188 3GF4 UPG 3.58974
189 3GF4 FAD 3.58974
190 1H82 GZZ 3.60169
191 1H82 FAD 3.60169
192 6F7L FAD 3.61991
193 2VVM FAD 3.63636
194 2VVL FAD 3.63636
195 1KYQ NAD 3.64964
196 1PL6 NAD 3.65169
197 1PL6 572 3.65169
198 5NA1 FAD 3.67647
199 1P77 ATR 3.67647
200 6GAR FAD 3.72493
201 4YCA NDP 3.7415
202 3CGD FAD 3.75
203 3CGD COA 3.75
204 3CGD NAD 3.75
205 2B4R AES 3.76812
206 2B4R NAD 3.76812
207 3HDY FAD 3.77834
208 3HDY FDA 3.77834
209 3HDY GDU 3.77834
210 1FNZ A2G 3.79747
211 4MO2 FDA 3.80435
212 4MO2 FAD 3.80435
213 1I8T FAD 3.81471
214 3OZ2 FAD 3.82514
215 1MUU NAD 3.82514
216 1MV8 NAD 3.82514
217 6C4T NA7 3.82514
218 1CF2 NAP 3.85757
219 3V1Y NAD 3.85757
220 2RAB NAD 3.88769
221 2RAB FAD 3.88769
222 4Z0H NAD 3.89222
223 1VDC FAD 3.9039
224 3E1T FAD 3.90625
225 1DIG NAP 3.92157
226 4HA6 FAD 3.93701
227 1PJS NAD 3.93873
228 3GFB NAD 4
229 5YB7 FAD 4.00729
230 5YB7 ORN 4.00729
231 2IID FAD 4.01606
232 2IID PHE 4.01606
233 3ZNN 4WL 4.03458
234 3ZNN FAD 4.03458
235 3WGT QSC 4.03458
236 3WGT FAD 4.03458
237 2B1N LYS ALA SER VAL GLY 4.06504
238 1KNR FAD 4.07407
239 3QJ4 FAD 4.09357
240 4ZGS NAD 4.14508
241 1O94 ADP 4.16667
242 1QO8 FAD 4.18944
243 4IV9 FAD 4.18944
244 1O0S NAI 4.18944
245 3Q9T FAY 4.18944
246 1GUZ NAD 4.19355
247 1QCI ADE 4.19847
248 3GDN HBX 4.22265
249 3GDN FAD 4.22265
250 4D04 NAP 4.24354
251 4D04 FAD 4.24354
252 5X9D 80F 4.27632
253 5TTJ FAD 4.28571
254 3H9E NAD 4.33526
255 4BV6 FAD 4.37158
256 4YNU LGC 4.37158
257 4YNU FAD 4.37158
258 1EZ4 NAD 4.40252
259 4JDR FAD 4.43038
260 3AB1 FAD 4.44444
261 5OCM NAP 4.46735
262 1BW9 NAD 4.49438
263 1BXG NAD 4.49438
264 2JB2 PHE 4.49898
265 2JB2 FAD 4.49898
266 1C1X NAD 4.50704
267 1GV0 NAD 4.51613
268 1BZL GCG 4.52675
269 1BZL FAD 4.52675
270 4YSX FAD 4.55373
271 3ULK NDP 4.55373
272 1B8U NAD 4.55927
273 2AG8 NAP 4.56274
274 2HJR APR 4.57317
275 5MQ6 NDP 4.58015
276 2OOR NAD 4.5977
277 2IVD FAD 4.60251
278 5JE8 NAD 4.63576
279 3ABI NAD 4.65753
280 2F1K NAP 4.6595
281 2PK3 A2R 4.6729
282 2PV7 NAD 4.69799
283 4RPL 3UC 4.73588
284 4RPL FAD 4.73588
285 2O4C NAD 4.73684
286 5TC4 NAD 4.74684
287 1EBF NAD 4.7486
288 5ZZ6 ADP 4.80769
289 5ZZ6 NAD 4.80769
290 1FL2 FAD 4.83871
291 1NPD NAD 4.86111
292 1NVT NAP 4.87805
293 1ELI PYC 4.88432
294 3GD4 NAD 4.91803
295 3GD4 FAD 4.91803
296 1XHC FAD 4.91803
297 2Z3Y F2N 4.91803
298 4MIG G3F 4.91803
299 1ZEM NAD 4.96183
300 4USR FAD 4.98615
301 5LD5 NAD 5.02793
302 2BGM NAJ 5.03597
303 5YEC ATP 5.04202
304 1PS9 FAD 5.10018
305 1PS9 NAP 5.10018
306 1GET NAP 5.11111
307 1GET FAD 5.11111
308 1HDG NAD 5.12048
309 5NUF NAD 5.12048
310 6GAS FAD 5.13595
311 2VYN NAD 5.13595
312 2CUL FAD 5.17241
313 5NII FAD 5.17799
314 5G3U FDA 5.20095
315 5G3U ITW 5.20095
316 1Y8Q ATP 5.20231
317 1Z0N BCD 5.20833
318 5EES NAP 5.26316
319 6F97 FAD 5.27307
320 6C4M NAP 5.27426
321 5UAV NDP 5.2795
322 5UAV TFB 5.2795
323 4OPC PGT 5.29801
324 4OPC FDA 5.29801
325 1YKJ FAD 5.32995
326 1YKJ PHB 5.32995
327 2ZQO NGA 5.38462
328 5BSH PRO 5.41516
329 3LZW FAD 5.42169
330 3LZW NAP 5.42169
331 5CAE COA 5.43131
332 1SC6 NAD 5.44554
333 4FWE FAD 5.46448
334 5FJN FAD 5.48246
335 5FJN BE2 5.48246
336 1X14 NAD 5.48628
337 1RYI GOA 5.49738
338 1RYI FAD 5.49738
339 4OM8 NAD 5.50162
340 4USQ FAD 5.54017
341 4RDH AMP 5.55556
342 4RDI ATP 5.55556
343 3QVP FAD 5.64663
344 3SQP FAD 5.64854
345 4E13 NAD 5.65371
346 5N6C NAD 5.66667
347 5Y77 FAD 5.70825
348 4CCN OGA 5.71429
349 1SOW NAD 5.79268
350 5Z20 NAI 5.7971
351 1KEW NAD 5.81717
352 1VL0 NAI 5.82192
353 5WGR FAD 5.82878
354 2ZXI FAD 5.82878
355 2GJP MAL 5.82878
356 5OVK NDP 5.85938
357 5Z21 NAI 5.86592
358 3UCL CYH 5.93368
359 3UCL FAD 5.93368
360 3UCL NAP 5.93368
361 4B4U NAP 5.94059
362 2YG3 FAD 5.96026
363 1NVM NAD 6.08974
364 5GZ6 NDP 6.13497
365 5GZ6 7C3 6.13497
366 5ZYN FAD 6.15711
367 4D79 ATP 6.15942
368 1WDK NAD 6.19308
369 3UOY NAP 6.23853
370 3UOY FAD 6.23853
371 5L95 AMP 6.25
372 2NU8 COA 6.25
373 1LUA NAP 6.27178
374 2XWL CTP 6.27803
375 1GT4 UNA 6.28931
376 5MZI FAD 6.29067
377 5MZI FYK 6.29067
378 5I39 FAD 6.37255
379 5NM7 GLY 6.39098
380 3CIF NAD 6.40669
381 3CIF G3H 6.40669
382 4ZRN UPG 6.41026
383 4XDZ NDP 6.41399
384 1CDO NAD 6.41711
385 3FIU POP 6.4257
386 6GNC FAD 6.46258
387 3H8V ATP 6.50685
388 1P1C SAH 6.53266
389 2D2I NAP 6.57895
390 5ZBC FAD 6.65188
391 4E5N NAD 6.66667
392 1A0J BEN 6.72646
393 1D4D FAD 6.73953
394 5HSA FAS 6.73953
395 1REO FAD 6.79012
396 3F8D FAD 6.81115
397 3RNM FAD 6.86869
398 3B1F NAD 6.89655
399 4CJX NAP 6.89655
400 5Y8L HUI 7.11864
401 5Y8L NAD 7.11864
402 3AXB PRO 7.14286
403 3AXB FAD 7.14286
404 1KJ8 GAR 7.16113
405 6CEP NAD 7.18563
406 6CEP OXM 7.18563
407 5TS5 FAD 7.2314
408 4C3Y FAD 7.35849
409 4C3Y ANB 7.35849
410 3B20 NAD 7.37463
411 3B1J NAD 7.37463
412 2Q7V FAD 7.38462
413 1FWV SGA MAG FUC 7.46269
414 4REP FAD 7.46812
415 3GMB FAD 7.46988
416 4J36 1HR 7.46988
417 4J36 FAD 7.46988
418 3WBF NAP 7.54098
419 5TUF TDC 7.57946
420 5TUF FAD 7.57946
421 6GNA FAD 7.63889
422 2HMT NAI 7.63889
423 3S5W FAD 7.77538
424 3S5W NAP 7.77538
425 5BUK FAD 7.77778
426 2R4J FAD 7.78443
427 2R4J 13P 7.78443
428 6C4N NAP 7.7951
429 1LSS NAD 7.85714
430 5HXI FAD 7.91557
431 5HXI 5HN 7.91557
432 4AT0 FAD 8.03922
433 1OC2 NAD 8.04598
434 1OC2 TDX 8.04598
435 3VPH NAD 8.06452
436 3VPH OXM 8.06452
437 3QFA FAD 8.09249
438 3MAG SAH 8.14332
439 3NT6 FAD 8.19672
440 3NTA FAD 8.19672
441 2YVJ NAI 8.25688
442 2YVJ FAD 8.25688
443 4EMI FAD 8.29268
444 4EMI NAD 8.29268
445 2HQM FAD 8.5595
446 1E6E FAD 8.59375
447 1Z82 NDP 8.65672
448 5EVY FAD 8.6758
449 5EVY SAL 8.6758
450 1LTH NAD 8.77743
451 2Y6Q FAD 9.04523
452 2Y6Q I7T 9.04523
453 5J60 FAD 9.0625
454 5K0A FAD 9.09091
455 3AD8 NAD 9.09091
456 3AD8 FAD 9.09091
457 3AD8 PYC 9.09091
458 2DT5 NAD 9.47867
459 3WMX NAD 9.49721
460 5BVA FAD 9.53545
461 1FEC FAD 9.59184
462 1ZK7 FAD 9.63597
463 3ITJ FAD 9.76331
464 5Z75 NAD 9.78593
465 2GOO NDG 9.80392
466 5ODQ FAD 10
467 5ODQ 9SB 10
468 5OKT 9XK 10.1911
469 5X20 NAD 10.2564
470 6FHO FAD 10.2757
471 6AA8 NAD 10.596
472 5MIT NAP 10.7034
473 5MIT FAD 10.7034
474 4X9M FAD 10.7656
475 3QV1 NAD 10.9756
476 3GGO NAI 11.1465
477 4GUT FAD 11.2903
478 4GUS FAD 11.2903
479 4HSU FAD 11.2903
480 2Q1S NAI 11.4058
481 3KYQ DPV 11.5578
482 1LDM NAD 12.1581
483 2A92 NAI 12.4611
484 2F5Z FAD 12.5
485 3K5I AIR 12.6551
486 1C0I BE2 12.6722
487 1C0I FAD 12.6722
488 4JK3 NAD 12.7413
489 4J4H NAI 12.7413
490 4J4H 1J1 12.7413
491 1GXU 2HP 13.1868
492 3HCH RSM 13.6986
493 3ORF NAD 14.741
494 1YKF NAP 14.7727
495 4XB2 NDP 14.9254
496 4XB2 HSE 14.9254
497 4II2 ATP 16.8675
498 2GAG NAD 19.1919
499 2GAG FOA 19.1919
500 2GAG FAD 19.1919
501 1PN0 IPH 19.49
502 1PN0 FAD 19.49
503 3QMN A3P 21.7054
504 1JNR FAD 22.6667
505 4BJZ P3A 25.9434
506 4BJZ FAD 25.9434
507 2DKH FAD 29.5082
508 2DKH 3HB 29.5082
509 5TUK FAD 32.8431
510 5KOX RFP 34.4538
511 5KOX FAD 34.4538
512 2RGJ FAD 34.8259
513 5EOW FAD 35.0617
514 2QA1 FAD 39.4
515 4K5S FAD 40.4851
516 4K5S PM0 40.4851
517 5BRT FAD 44.4444
518 5BRT CH9 44.4444
Pocket No.: 2; Query (leader) PDB : 4EIP; Ligand: FAD; Similar sites found with APoc: 781
This union binding pocket(no: 2) in the query (biounit: 4eip.bio1) has 47 residues
No: Leader PDB Ligand Sequence Similarity
1 4KVL PLM 1.0929
2 4Z24 FAD 1.27505
3 1GQ2 NAP 1.27505
4 1GZ4 ATP 1.27505
5 4RQU NAD 1.33333
6 3MCT SAH 1.3468
7 3ICS ADP 1.45719
8 3ICT ADP 1.45719
9 3ICS FAD 1.45719
10 3ICR FAD 1.45719
11 3ICT FAD 1.45719
12 1V8B NAD 1.46138
13 1E5Q NDP 1.55556
14 4OBW SAM 1.55642
15 1A5Z NAD 1.5674
16 4RSL FAD 1.57303
17 3A06 NDP 1.59574
18 4KRI SAH 1.61663
19 1F8F NAD 1.61725
20 1UXG FUM 1.61812
21 1UXG NAD 1.61812
22 4C4A SAH 1.63934
23 1O6Z NAD 1.65016
24 1JN2 SFP 1.68776
25 5DX8 SFG 1.7192
26 1R37 NAD 1.72911
27 3V1U NAD 1.7316
28 1RSG FAD 1.74419
29 1YY5 FAD 1.75439
30 3GU3 SAH 1.76056
31 4ZCC FAD 1.78571
32 4ZCC NAI 1.78571
33 1DSS NAD 1.8018
34 3G5S FAD 1.80587
35 2RGH FAD 1.82149
36 3X0D SAH 1.82149
37 1L7E NAI 1.82292
38 6BWL NAD 1.82927
39 3DMH SAM 1.83727
40 4D7E FAD 1.8648
41 2EG5 SAH 1.88172
42 1TB4 PEJ 1.88679
43 1MO9 KPC 1.91205
44 1MO9 FAD 1.91205
45 5VN0 FAD 1.9305
46 5VN0 NAI 1.9305
47 5AYV NAP 1.94175
48 1HYH NAD 1.94175
49 5AYV KPL 1.94175
50 1COY AND 1.97239
51 1COY FAD 1.97239
52 1YS4 NAP 1.9774
53 1YJQ NAP 1.9802
54 5GSN MMZ 1.98676
55 5GSN FAD 1.98676
56 5GSN NAP 1.98676
57 1X87 NAD 1.99637
58 5JJR SAH 2.00364
59 2YYY NAP 2.04082
60 1J0X NAD 2.10843
61 2VHW NAI 2.12202
62 2WET FAD 2.15264
63 2XVE FAD 2.15517
64 4LWP SAH 2.17391
65 2ZO9 MLI 2.18978
66 2V6G NAP 2.1978
67 3AYI HCI 2.21914
68 3AYI FAD 2.21914
69 3QWI NAP 2.22222
70 1X7D NAD 2.28571
71 3NJ4 NAD 2.29885
72 3NJ4 AFX 2.29885
73 5JWC FAD 2.30326
74 1ORR NAD 2.30548
75 2RGO FAD 2.30643
76 4XQC NAD 2.31579
77 4XQC 13D 2.31579
78 3KLJ FAD 2.33766
79 5A1T NAI 2.34604
80 5A1T OXM 2.34604
81 4NTD FAD 2.35294
82 1F8G NAD 2.36794
83 6ER9 FAD 2.36794
84 6ER9 NAP 2.36794
85 4GKV NAD 2.38095
86 5AHO TLA 2.38095
87 1E1M FAD 2.3913
88 1E1M NAP 2.3913
89 5UAO FAD 2.40296
90 1XDS SAM 2.40642
91 1V6A TRE 2.40964
92 9LDT NAD 2.40964
93 9LDB NAD 2.40964
94 4ZVV NAD 2.40964
95 4ZVV GN0 2.40964
96 1D1T NAD 2.41287
97 1GAD NAD 2.42424
98 2VDV SAM 2.43902
99 1ZQ9 SAM 2.45614
100 4DSG UDP 2.47934
101 4DSG FAD 2.47934
102 3U7Q HCA 2.48566
103 2GSD NAD 2.48756
104 1I9G SAM 2.5
105 1K3T BRZ 2.50696
106 2OG2 MLI 2.50696
107 3DAG FEG 2.51397
108 3LAD FAD 2.52101
109 4U8P UDP 2.53411
110 4U8P FDA 2.53411
111 2HK9 ATR 2.54545
112 2HK9 NAP 2.54545
113 1GTE FAD 2.55009
114 5DNK SAH 2.55009
115 3K7M FAD 2.5522
116 3A4T SFG 2.55474
117 4CNK FAD 2.55754
118 1KEV NDP 2.5641
119 1WPQ NAD 2.5788
120 1NYT NAP 2.58303
121 2DFV NAD 2.59366
122 4B63 FAD 2.59481
123 4B63 ORN 2.59481
124 4B63 NAP 2.59481
125 2VWT PYR 2.62172
126 2P41 SAH 2.62295
127 4M37 SAH 2.62391
128 4M38 SAH 2.62391
129 2C7G FAD 2.63158
130 2C7G ODP 2.63158
131 1Y1P NMN AMP PO4 2.63158
132 3WLE NAD 2.6393
133 5WP5 SAH 2.64766
134 5A04 BGC 2.65487
135 5A04 NDP 2.65487
136 4R5M NAP 2.65957
137 4R5M 4NO 2.65957
138 2NVK NAP 2.66393
139 2NVK FAD 2.66393
140 1RM4 NDP 2.67062
141 4L8V NAP 2.67062
142 3L4S NAD 2.67857
143 3L4S 3PG 2.67857
144 1CER NAD 2.71903
145 1V59 NAD 2.71967
146 1V59 FAD 2.71967
147 3O7W SAM 2.72109
148 3NKS FAD 2.72537
149 2GMH FAD 2.73224
150 5OC1 FAD 2.73224
151 1GPE FAD 2.73224
152 1DLJ NAI 2.73632
153 1DLJ UGA 2.73632
154 1YQZ FAD 2.73973
155 2AOT SAH 2.73973
156 2E5V FAD 2.75424
157 2NXE SAM 2.75591
158 1WP4 NDP 2.76817
159 2CVZ NDP 2.76817
160 1Q1R FAD 2.78422
161 2AQJ FAD 2.7881
162 2AQJ TRP 2.7881
163 5JCA FAD 2.8169
164 5JCA NDP 2.8169
165 5H81 NAP 2.82776
166 2WPF WPF 2.82828
167 2WPF FAD 2.82828
168 3GEG NAD 2.83401
169 1LJ8 NAD 2.83976
170 1M2W NAD 2.83976
171 1LDN NAD 2.8481
172 4YKG NAD 2.87908
173 4YKG FAD 2.87908
174 5KKA 6V0 2.88462
175 5C9P FUC 2.88714
176 5YAP NAI 2.89474
177 5YAP 8S0 2.89474
178 4YRY NAD 2.89855
179 4YRY FAD 2.89855
180 5TWB FAD 2.90698
181 2NPX FAD 2.90828
182 2NPX NAD 2.90828
183 4TXI FAD 2.91439
184 1Q9I TEO 2.91439
185 1Q9I FAD 2.91439
186 5M67 3D1 2.92276
187 5M67 ADE 2.92276
188 5M67 NAD 2.92276
189 2HNK SAH 2.92887
190 1P31 EPU 2.94737
191 1P3D UMA 2.94737
192 3FG2 FAD 2.9703
193 3B9Q MLI 2.98013
194 4PLG OXM 2.99401
195 4PLG NAI 2.99401
196 4POO SAM 3
197 2CDC XYP 3.00546
198 2CDC NAP 3.00546
199 4PLT NAI 3.02115
200 4PLT OXM 3.02115
201 1QMG APX 3.05344
202 1GEE NAD 3.06513
203 5ZI9 FLC 3.07692
204 3LXD FAD 3.09654
205 5OJL TXP 3.09654
206 1NAA 6FA 3.09654
207 1DJN ADP 3.09654
208 6H3O FAD 3.09654
209 1NAA ABL 3.09654
210 4BVA NDP 3.09654
211 2CDU FAD 3.09735
212 5N5D SAM 3.09735
213 2CDU ADP 3.09735
214 3NYC FAD 3.14961
215 3NYC IAR 3.14961
216 5UR0 NAD 3.15186
217 1USI PHE 3.17919
218 5ZI2 NAD 3.18841
219 5ZI2 ADP 3.18841
220 1RL4 BL5 3.19149
221 3T31 FAD 3.20366
222 3T31 DCQ 3.20366
223 1P0F NAP 3.21716
224 5MBX SP5 3.21932
225 5MBX FAD 3.21932
226 4XDY NAI 3.25444
227 2VT3 ATP 3.25581
228 3EVG SAH 3.27273
229 3NTD FAD 3.27869
230 4J56 FAD 3.27869
231 6FP4 FAD 3.27869
232 5J7X FAD 3.27869
233 4AP3 FAD 3.27869
234 4AP3 NAP 3.27869
235 6FP4 E1T 3.27869
236 3F81 STT 3.27869
237 1N1G BCP 3.27869
238 6FDF SAH 3.29341
239 5NMX FAD 3.29412
240 5NMX NAP 3.29412
241 3LU1 NAD 3.2967
242 1J49 NAD 3.3033
243 2NAD NAD 3.30789
244 1PZG A3D 3.32326
245 5X68 FAD 3.32481
246 4YMH SAH 3.33333
247 3Q3C NAD 3.34448
248 1UP7 NAD 3.35731
249 3T7S SAM 3.35821
250 4QTU SAM 3.36538
251 6EL3 NAP 3.41207
252 1OMO NAD 3.41615
253 4OSP NAP 3.42205
254 5J5Z FAD 3.42742
255 2YVF NAD 3.43137
256 2YVF FAD 3.43137
257 4M52 FAD 3.43348
258 4M52 M52 3.43348
259 2ZJ1 ARJ 3.43434
260 2ZJ1 NAD 3.43434
261 1F06 NDP 3.4375
262 3CTY FAD 3.44828
263 2A8X FAD 3.44828
264 2XVF FAD 3.44828
265 5N2I NAP 3.44828
266 1LVL FAD 3.46084
267 4MOP 2H5 3.46084
268 1R6D NAD 3.46084
269 1R6D DAU 3.46084
270 4ISS TAR 3.46084
271 1LVL NAD 3.46084
272 1DL5 SAH 3.47003
273 3P13 RIP 3.47222
274 1TDF NAP 3.48101
275 1TDF FAD 3.48101
276 4JJF FE9 3.48837
277 2FR1 NDP 3.49794
278 4UP3 FAD 3.50318
279 4UP3 NDP 3.50318
280 3X0V FAD 3.51201
281 5U8U FAD 3.5343
282 2Q0L FAD 3.53698
283 2Q0L NAP 3.53698
284 2B9W FAD 3.53774
285 3CGB FAD 3.54167
286 4D3F NAP 3.54839
287 2G5C NAD 3.55872
288 3GF4 FAD 3.58974
289 3GF4 UPG 3.58974
290 1H82 GZZ 3.60169
291 1H82 FAD 3.60169
292 6F3N ADN 3.60169
293 6F3N NAD 3.60169
294 4Y9D NAI 3.60656
295 1O5I NAD 3.61446
296 6F7L FAD 3.61991
297 2VVL FAD 3.63636
298 2VVM FAD 3.63636
299 1KYQ NAD 3.64964
300 1PL6 NAD 3.65169
301 1PL6 572 3.65169
302 2CVQ NDP 3.66972
303 1P77 ATR 3.67647
304 5NA1 FAD 3.67647
305 1HDR NAD 3.68852
306 6F3M NAD 3.69565
307 6GAR FAD 3.72493
308 4YCA NDP 3.7415
309 3CGD FAD 3.75
310 3CGD COA 3.75
311 3CGD NAD 3.75
312 2B4R AES 3.76812
313 2B4R NAD 3.76812
314 3HDY FAD 3.77834
315 3HDY FDA 3.77834
316 3HDY GDU 3.77834
317 4MO2 FDA 3.80435
318 4MO2 FAD 3.80435
319 1I8T FAD 3.81471
320 3OZ2 FAD 3.82514
321 1MUU NAD 3.82514
322 1MV8 NAD 3.82514
323 6C4T NA7 3.82514
324 3V1Y NAD 3.85757
325 1CF2 NAP 3.85757
326 2RAB NAD 3.88769
327 2RAB FAD 3.88769
328 4Z0H NAD 3.89222
329 3GCZ SAM 3.90071
330 1VDC FAD 3.9039
331 6BII NAP 3.9039
332 3E1T FAD 3.90625
333 6A0S NDP 3.91566
334 6A0S HSE 3.91566
335 1ZGA SAH 3.92157
336 1DIG NAP 3.92157
337 4HA6 FAD 3.93701
338 1PJS NAD 3.93873
339 2WA2 SAM 3.98551
340 1N2X SAM 3.98671
341 3GFB NAD 4
342 5YB7 FAD 4.00729
343 5YB7 ORN 4.00729
344 2IID FAD 4.01606
345 2IID PHE 4.01606
346 2QGI UDP 4.03226
347 3ZNN FAD 4.03458
348 3ZNN 4WL 4.03458
349 3WGT QSC 4.03458
350 3WGT FAD 4.03458
351 2B1N LYS ALA SER VAL GLY 4.06504
352 1KNR FAD 4.07407
353 3QJ4 FAD 4.09357
354 2WD7 NAP 4.10448
355 1KYZ SAH 4.10959
356 4ZGS NAD 4.14508
357 4GLL NAD 4.1543
358 1O94 ADP 4.16667
359 1QO8 FAD 4.18944
360 1O0S NAI 4.18944
361 4IV9 FAD 4.18944
362 3Q9T FAY 4.18944
363 1GUZ NAD 4.19355
364 4KIB SAH 4.20168
365 1U7T NAD 4.21456
366 1E3W NAD 4.21456
367 3GDN HBX 4.22265
368 3GDN FAD 4.22265
369 1E6W NAD 4.23077
370 4D04 NAP 4.24354
371 4D04 FAD 4.24354
372 2OUA AES 4.25532
373 5X9D 80F 4.27632
374 5TTJ FAD 4.28571
375 4TQG NDP 4.33437
376 3H9E NAD 4.33526
377 4BV6 FAD 4.37158
378 4YNU LGC 4.37158
379 4YNU FAD 4.37158
380 1LLU NAD 4.38596
381 1EZ4 NAD 4.40252
382 3G89 SAM 4.41767
383 4JDR FAD 4.43038
384 5ERG SAM 4.43864
385 3AB1 FAD 4.44444
386 1H2B NAJ 4.45682
387 5W0N 2KH 4.4665
388 5OCM NAP 4.46735
389 5IDM C2E 4.46927
390 5E9W SAH 4.48718
391 1BW9 NAD 4.49438
392 1BXG NAD 4.49438
393 3RFV 15L 4.49438
394 3RFV NAI 4.49438
395 2JB2 PHE 4.49898
396 2JB2 FAD 4.49898
397 1C1X NAD 4.50704
398 1GV0 NAD 4.51613
399 4J1Q NDP 4.52586
400 1BZL FAD 4.52675
401 1BZL GCG 4.52675
402 4YSX FAD 4.55373
403 3ULK NDP 4.55373
404 1B8U NAD 4.55927
405 2AG8 NAP 4.56274
406 5GT9 NAP 4.56274
407 2HJR APR 4.57317
408 5MQ6 NDP 4.58015
409 2OOR NAD 4.5977
410 2IVD FAD 4.60251
411 2O07 MTA 4.60526
412 2O07 SPD 4.60526
413 5N53 8NB 4.61538
414 3OFK SAH 4.62963
415 5JE8 NAD 4.63576
416 3ABI NAD 4.65753
417 2F1K NAP 4.6595
418 1VI2 NAD 4.66667
419 2PK3 A2R 4.6729
420 2PV7 NAD 4.69799
421 4YAC NAI 4.7138
422 5F1V 3VN 4.7138
423 5LOG SAH 4.72103
424 4RPL 3UC 4.73588
425 4RPL FAD 4.73588
426 2O4C NAD 4.73684
427 5TC4 NAD 4.74684
428 1EBF NAD 4.7486
429 3SJ7 NDP 4.7619
430 1KOL NAD 4.77387
431 2DBZ NAP 4.79042
432 3CMC NAD 4.79042
433 5ZZ6 ADP 4.80769
434 5ZZ6 NAD 4.80769
435 1FL2 FAD 4.83871
436 4URF NAD 4.83871
437 3EGI ADP 4.85437
438 1NPD NAD 4.86111
439 5BW4 SAM 4.86891
440 3HAD NAD 4.87013
441 1NVT NAP 4.87805
442 1ELI PYC 4.88432
443 4N49 SAM 4.90654
444 3GD4 NAD 4.91803
445 3GD4 FAD 4.91803
446 1XHC FAD 4.91803
447 2Z3Y F2N 4.91803
448 4MIG G3F 4.91803
449 2EV9 NAP 4.94297
450 2EV9 SKM 4.94297
451 1ZEM NAD 4.96183
452 4USR FAD 4.98615
453 5LD5 NAD 5.02793
454 2BGM NAJ 5.03597
455 5YEC ATP 5.04202
456 2B5W NAP 5.04202
457 1PS9 FAD 5.10018
458 1PS9 NAP 5.10018
459 1GET NAP 5.11111
460 1GET FAD 5.11111
461 1HDG NAD 5.12048
462 5NUF NAD 5.12048
463 5NUE NAD 5.12048
464 2YY7 NAD 5.12821
465 6GAS FAD 5.13595
466 2VYN NAD 5.13595
467 4PIV NDP 5.15152
468 2CUL FAD 5.17241
469 2JJQ SAH 5.17647
470 5FA5 MTA 5.17711
471 5NII FAD 5.17799
472 2IXB NAD 5.18018
473 4YAG NAI 5.19031
474 5G3U FDA 5.20095
475 5G3U ITW 5.20095
476 1Y8Q ATP 5.20231
477 3AY6 NAI 5.20446
478 1Z0N BCD 5.20833
479 5EES NAP 5.26316
480 6F97 FAD 5.27307
481 6C4M NAP 5.27426
482 5UAV NDP 5.2795
483 5UAV TFB 5.2795
484 1Z45 NAD 5.28233
485 4OPC PGT 5.29801
486 4OPC FDA 5.29801
487 3OND ADN 5.32787
488 3OND NAD 5.32787
489 1YKJ FAD 5.32995
490 1YKJ PHB 5.32995
491 2ZQO NGA 5.38462
492 5KVA SAM 5.39568
493 5BSH PRO 5.41516
494 1OBB NAD 5.41667
495 3LZW FAD 5.42169
496 3LZW NAP 5.42169
497 5U5G NAP 5.42373
498 5CAE COA 5.43131
499 1SC6 NAD 5.44554
500 4FWE FAD 5.46448
501 5FJN FAD 5.48246
502 5FJN BE2 5.48246
503 1X14 NAD 5.48628
504 1RYI GOA 5.49738
505 1RYI FAD 5.49738
506 4OM8 NAD 5.50162
507 2DC1 NAD 5.50847
508 4USQ FAD 5.54017
509 1SAY PYR 5.54017
510 4RDH AMP 5.55556
511 4RDI ATP 5.55556
512 6GFK SAH 5.57769
513 1HKU NAD 5.58659
514 2PT9 S4M 5.60748
515 3QVP FAD 5.64663
516 3SQP FAD 5.64854