Receptor
PDB id Resolution Class Description Source Keywords
4EKL 2 Å EC: 2.7.11.1 AKT1 WITH GDC0068 HOMO SAPIENS PHOSPHOTRANSFERASE TRANSFERASE
Ref.: AN ATP-SITE ON-OFF SWITCH THAT RESTRICTS PHOSPHATAS ACCESSIBILITY OF AKT. SCI.SIGNAL. V. 5 RA37 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
0RF A:501;
Valid;
none;
ic50 = 5 nM
457.996 C24 H32 Cl N5 O2 C[C@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3MVH 2.01 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF AKT-1-INHIBITOR COMPLEXES HOMO SAPIENS KINASE INHIBITOR TRANSFERASE
Ref.: DESIGN OF SELECTIVE, ATP-COMPETITIVE INHIBITORS OF J.MED.CHEM. V. 53 4615 2010
Members (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 107 families.
1 3QKK - SMH C28 H38 N2 O7 S CCOCCN(C[C....
2 4EKL ic50 = 5 nM 0RF C24 H32 Cl N5 O2 C[C@@H]1C[....
3 3CQW ic50 = 42 nM CQW C12 H11 Cl N6 c1c(c2c([n....
4 4GV1 ic50 = 3 nM 0XZ C21 H25 Cl N6 O2 c1cc(ccc1[....
5 3MVH ic50 = 0.5 nM WFE C20 H22 F2 N6 O CCc1c[nH]c....
6 3MV5 ic50 = 180 nM XFE C11 H15 N5 Cc1c[nH]c2....
7 3QKL - SMR C29 H40 N4 O5 S CCOCC[N@@]....
8 3QKM ic50 = 0.038 uM SM9 C31 H43 N5 O4 S CCOCCN(C[C....
9 3CQU ic50 = 151 nM CQU C15 H13 N7 Cc1[nH]c(n....
70% Homology Family (18)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 82 families.
1 1O6L - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
2 2JDO ic50 = 0.23 uM I5S C20 H22 Cl N3 O3 S c1cc2cnccc....
3 1O6K - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
4 3E88 Ki = 2 nM G96 C24 H27 N7 O3 CCn1c2cc(n....
5 2UW9 - GVP C20 H20 Cl N3 c1cc(ccc1c....
6 2JDR ic50 = 0.5 nM L20 C24 H23 N5 O Cc1c2cc(cc....
7 3D0E ic50 = 13 nM G93 C21 H27 N7 O3 CCn1c2c(cn....
8 2X39 ic50 = 30 nM X39 C19 H21 Cl N6 O c1cc(ccc1C....
9 3E87 - GLY ARG PRO ARG THR THR SER PHE ALA GLU n/a n/a
10 3QKK - SMH C28 H38 N2 O7 S CCOCCN(C[C....
11 4EKL ic50 = 5 nM 0RF C24 H32 Cl N5 O2 C[C@@H]1C[....
12 3CQW ic50 = 42 nM CQW C12 H11 Cl N6 c1c(c2c([n....
13 4GV1 ic50 = 3 nM 0XZ C21 H25 Cl N6 O2 c1cc(ccc1[....
14 3MVH ic50 = 0.5 nM WFE C20 H22 F2 N6 O CCc1c[nH]c....
15 3MV5 ic50 = 180 nM XFE C11 H15 N5 Cc1c[nH]c2....
16 3QKL - SMR C29 H40 N4 O5 S CCOCC[N@@]....
17 3QKM ic50 = 0.038 uM SM9 C31 H43 N5 O4 S CCOCCN(C[C....
18 3CQU ic50 = 151 nM CQU C15 H13 N7 Cc1[nH]c(n....
50% Homology Family (29)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 55 families.
1 2YM8 ic50 = 0.013 uM YM8 C19 H19 Cl N6 O C[C@H](CN(....
2 2CGW ic50 = 17.3 uM 3C3 C9 H15 N9 O2 CCCn1c(nc(....
3 3F9N ic50 = 1.3 uM 38M C29 H35 Cl N4 O2 S CCCC[C@@H]....
4 4JIK ic50 = 0.039 uM 1KO C18 H19 Cl N6 O c1cc(ccc1c....
5 4QYH ic50 = 0.0013 uM 3DX C22 H20 N6 CN1CCN(CC1....
6 2BRB Ki = 13.7 uM PFQ C20 H17 N3 O2 c1ccc(cc1)....
7 3PA3 ic50 = 1 nM C70 C18 H18 Cl N5 O S c1cc(ccc1c....
8 2YER ic50 = 0.02 uM TQ1 C15 H12 N4 O2 c1cc([nH]c....
9 3NLB ic50 = 35 nM 5BE C21 H28 N6 O Cc1c(c([nH....
10 3JVR Ki = 1.89 uM AGX C16 H13 Cl2 N3 O2 C[C@@H](c1....
11 2WMX ic50 = 0.86 uM ZY6 C17 H19 N5 O c1ccc(cc1)....
12 1SZM ic50 = 6.35 uM BI4 C27 H26 N4 O2 C[N@]1CCC[....
13 2HY0 ic50 = 0.65 nM 306 C26 H25 N5 O c1cc2c(cc1....
14 5LVO - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
15 4XX9 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
16 2XCK ic50 = 713 nM MH4 C29 H33 N9 O Cc1cc(ccn1....
17 2PE1 ic50 = 6 nM 517 C15 H14 N4 O2 CC(c1ccc[n....
18 3RWP Ki = 0.6 nM ABQ C24 H24 F N7 O2 CC(C)n1cc(....
19 3NAX - MP7 C28 H22 F2 N4 O4 c1ccc(cc1)....
20 3QCQ ic50 = 0.00000001 M 3Q0 C13 H15 N7 CCNc1cc(nc....
21 4A06 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
22 2UW9 - GVP C20 H20 Cl N3 c1cc(ccc1c....
23 2JDR ic50 = 0.5 nM L20 C24 H23 N5 O Cc1c2cc(cc....
24 3UBD Kd = 2.9 uM SL0 C25 H24 O12 CC1C(C(C(C....
25 4GUE Kd = 5.8 uM QCT C21 H20 O11 C[C@H]1[C@....
26 3G51 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
27 3QKK - SMH C28 H38 N2 O7 S CCOCCN(C[C....
28 4EKL ic50 = 5 nM 0RF C24 H32 Cl N5 O2 C[C@@H]1C[....
29 3WF5 ic50 = 81 nM FZ8 C17 H17 N7 c1ccc2c(c1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 0RF; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 0RF 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3MVH; Ligand: WFE; Similar sites found: 311
This union binding pocket(no: 1) in the query (biounit: 3mvh.bio1) has 31 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1OPB RET 0.01916 0.40089 None
2 3NKS ACJ 0.006024 0.42459 0.877193
3 1U08 PLP 0.0316 0.40052 1.16959
4 4Y24 TD2 0.00345 0.44914 1.2987
5 3V4S ATP 0.00258 0.4268 1.46199
6 4BTV RB3 0.02507 0.41615 1.46199
7 3I0O ADP 0.0001395 0.51916 1.47493
8 3OYW TDG 0.01689 0.42279 1.49254
9 4ZS4 ATP 0.00002828 0.52216 1.62866
10 2AQX ATP 0.002638 0.42638 1.7301
11 2PYW ADP 0.000003943 0.55442 1.75439
12 3X01 AMP 0.0002608 0.52222 1.75439
13 5MRH Q9Z 0.0007557 0.48806 1.75439
14 5MW8 ATP 0.00003458 0.45091 1.75439
15 2Q7D ANP 0.002385 0.41549 1.75439
16 3PDT ADP 0.00005326 0.52701 1.81818
17 4D52 GXL 0.01649 0.41655 1.90476
18 4D52 GIV 0.03515 0.40361 1.90476
19 1ZP9 ATP 0.0000005396 0.62263 1.93798
20 1ZTH ADP 0.0000005921 0.45009 1.93798
21 4RDL FUC GAL NDG FUC 0.02767 0.41267 1.94805
22 3T5M AMP 0.03454 0.40756 2.08333
23 2QHS OCA 0.003053 0.45181 2.1097
24 4OUJ LBT 0.002254 0.46815 2.28013
25 1EHI ADP 0.001363 0.44646 2.33918
26 2PNC CLU 0.01713 0.42464 2.33918
27 2QHV OC9 0.001809 0.46853 2.38095
28 5C1P ADP 0.0008993 0.47316 2.61438
29 5C1P DAL DAL 0.006504 0.40067 2.61438
30 5KBE IPH 0.02161 0.41708 2.62009
31 5GZ9 ANP 0.0000004037 0.51629 2.62295
32 5I35 ANP 0.000000596 0.61248 2.63158
33 2IVD ACJ 0.0128 0.41647 2.63158
34 2VPQ ANP 0.0006603 0.4063 2.63158
35 3TM0 ANP 0.001226 0.40939 2.6616
36 3TM0 B31 0.001331 0.40405 2.6616
37 1QVJ RP5 0.04288 0.40147 2.73973
38 1Q6O LG6 0.0167 0.40371 2.77778
39 3VPC ADP 0.0002293 0.47224 2.83688
40 3TII ANP 0.001174 0.47268 2.92398
41 4CYI ATP 0.000007751 0.45779 2.92398
42 2CFM AMP 0.002402 0.45705 2.92398
43 2VQD AP2 0.0009633 0.44918 2.92398
44 3HQP OXL 0.03935 0.40289 2.92398
45 1RZX ACE VAL LYS GLU SER LEU VAL 0.04219 0.40396 3.06122
46 4ZGP ADP 0.01554 0.40519 3.07167
47 2AGC DAO 0.01996 0.41466 3.08642
48 2ZTG A5A 0.01559 0.40185 3.21637
49 1OBD ATP 0.00009462 0.40943 3.26797
50 2IF8 ADP 0.00009328 0.54221 3.50877
51 3WVR AMP 0.0001297 0.50847 3.50877
52 4U98 ACP 0.0001601 0.49855 3.50877
53 3NEM ATP 0.01359 0.41913 3.50877
54 3O0W MAN MAN MAN GLC 0.03216 0.40013 3.663
55 2QX0 PH2 0.008243 0.43991 3.77358
56 3VOT ADP 0.0003719 0.49776 3.80117
57 4UWH JXM 0.002096 0.45051 3.80117
58 3DNT ATP 0.001645 0.42835 3.80117
59 3ZJX BOG 0.00554 0.45122 3.80623
60 3PA8 621 0.04449 0.40025 3.93701
61 3BU1 HSM 0.0336 0.40056 4.05405
62 5D9G GLU ASN LEU TYR PHE GLN 0.009076 0.43239 4.06504
63 4LO2 GAL BGC 0.003968 0.45787 4.08163
64 4OCV ANP 0.0001632 0.48792 4.09357
65 4OCJ NDG 0.0002458 0.45485 4.09357
66 4PU5 ANP 0.000876 0.44333 4.09357
67 3K5I ADP 0.002154 0.43377 4.21836
68 1TQP ATP 0.000004437 0.53522 4.25532
69 5E89 TD2 0.004403 0.43099 4.31655
70 4DFU QUE 0.007719 0.44085 4.34783
71 4FFG LBS 0.01163 0.42713 4.38596
72 5TT6 ATP 0.002547 0.42704 4.38596
73 3VSV XYS 0.02398 0.41765 4.38596
74 2GEK GDP 0.02666 0.40068 4.38596
75 2G30 ALA ALA PHE 0.000452 0.46633 4.65116
76 5C4L 4XR 0.0000465 0.47394 4.6729
77 5C4L SIS 0.0001778 0.45166 4.6729
78 2BKK ADP 0.00006261 0.52994 4.73373
79 1YXM ADE 0.01319 0.42621 4.9505
80 4GYI ADP 0.00002392 0.55045 4.97076
81 3ORQ ADP 0.002126 0.43402 4.97076
82 4NOS ITU 0.03782 0.40016 4.97076
83 3OCP CMP 0.02525 0.40548 5.03597
84 4FE2 AIR 0.001126 0.47359 5.09804
85 4FE2 ADP 0.01841 0.40866 5.09804
86 1PVC ILE SER GLU VAL 0.04483 0.41146 5.16605
87 2YRX AMP 0.003164 0.46287 5.26316
88 4WOE ADP 0.01608 0.42574 5.26316
89 4WOE 3S5 0.03544 0.40492 5.26316
90 4RT1 C2E 0.000814 0.46542 5.35714
91 5EWK P34 0.02573 0.41494 5.5
92 5DZT AMP 0.0007706 0.49474 5.55556
93 4RYV ZEA 0.002086 0.46012 5.80645
94 4R78 AMP 0.00003631 0.55593 5.82524
95 3UDZ ADP 0.00001586 0.44408 5.84795
96 4NS0 PIO 0.01649 0.4259 6.01504
97 5XLY C2E 0.00799 0.41525 6.01504
98 2IO8 ADP 0.000579 0.44722 6.14035
99 3KYG 5GP 5GP 0.01349 0.40158 6.1674
100 3AB4 THR 0.02653 0.40822 6.17978
101 3TDV GDP 0.000004965 0.56255 6.20915
102 4DSU BZI 0.02525 0.41238 6.34921
103 4O4F ATP 0.001048 0.4331 6.45161
104 4O4F IHP 0.001251 0.42674 6.45161
105 4LH7 1X8 0.001877 0.46897 6.50155
106 4WOP CTP 0.01504 0.40587 6.66667
107 5KJW 53C 0.00335 0.46098 6.72515
108 2G50 PYR 0.03004 0.40813 6.72515
109 1TZD ADP 0.0002989 0.5118 6.90909
110 4O1P ANP 0.00000001507 0.53065 7.01754
111 1W2D ADP 0.0004394 0.49412 7.16981
112 1W2D 4IP 0.004123 0.40595 7.16981
113 2VK2 GZL 0.02334 0.41559 7.18954
114 3DGY 2GP 0.03301 0.40782 7.2165
115 4CC6 L5Y 0.006901 0.43854 7.2327
116 1UPR 4IP 0.04505 0.40064 7.31707
117 5W2I ADP 0.0008425 0.44044 7.393
118 5W2I I3P 0.0008425 0.44044 7.393
119 4WW7 AMP 0.0000001856 0.52059 7.48663
120 5IQD GNP 0.000004727 0.52065 7.54098
121 5IQD RIO 0.000005191 0.52065 7.54098
122 4AZT LY2 0.0005563 0.48898 7.89474
123 4IX4 ADP 0.00000374 0.4742 7.89474
124 4AZW ATP 0.00001363 0.45523 7.89474
125 4XYM A12 0.0007581 0.45792 8.26087
126 4Q5H ANP 0.000001494 0.58649 8.33333
127 1PK8 ATP 0.000779 0.43836 8.47953
128 1IA9 ANP 0.00001631 0.53291 8.57143
129 1I7L ATP 0.0004234 0.45287 8.73786
130 4USI AKG 0.009895 0.44216 9.09091
131 2GQS C2R 0.001563 0.45663 9.2827
132 2GQS ADP 0.002151 0.44561 9.2827
133 4ANW O92 0.001495 0.40737 9.64912
134 4KU7 PCG 0.0229 0.40396 9.80392
135 1UYY BGC BGC 0.03575 0.40537 9.92366
136 4CS9 AMP 0.005262 0.43285 10.0529
137 2YW2 ATP 0.0003524 0.46843 10.2339
138 4OYA 1VE 0.008949 0.41254 10.2339
139 3HAV ATP 0.00012 0.53976 10.3679
140 4WVW SLT 0.024 0.40224 10.4167
141 5CKW ANP 0.000001639 0.61609 10.5263
142 3W0O HY0 0.0003185 0.4404 10.6017
143 3W0O ADP 0.0003185 0.4404 10.6017
144 2PUL ACP 0.000006805 0.56288 11.4035
145 5EPA AKG 0.01581 0.4243 12.1864
146 1FWV SGA MAG FUC 0.006452 0.44582 12.6866
147 2XG5 EC2 0.004774 0.45524 13.3028
148 2XG5 EC5 0.004774 0.45524 13.3028
149 5LXT ACP 0.000832 0.44428 13.986
150 4OPC FDA 0.02894 0.40532 14.0351
151 4OAV ACP 0.000000006057 0.70596 15.7895
152 2CSN CKI 0.0003508 0.46677 17.5084
153 4XMF HSM 0.001351 0.48472 17.9348
154 1CBK ROI 0.0169 0.42388 18.125
155 2XCM ADP 0.01672 0.40711 18.4783
156 5MY8 RXZ 0.0000001307 0.59254 19.0058
157 3VHE 42Q 0.000002819 0.51856 19.883
158 2DTJ THR 0.03187 0.40032 20.7865
159 3VPB ADP 0.0001501 0.46758 21.4286
160 1EB1 ASP TYR GLU PRO ILE PRO GLU GLU ALA PHE 0.02538 0.40174 22.2222
161 4YZC STU 0.0000001208 0.58294 23.9766
162 4FL3 ANP 0.00000002305 0.64497 25.4386
163 5AWM ANP 0.0000004372 0.64491 26.6082
164 4IZY 1J2 0.0000001707 0.61451 26.6082
165 5HCY 60D 0.000001676 0.45893 26.8882
166 4XH0 ADP 0.0000008876 0.65499 26.9006
167 4UX9 ANP 0.000000004393 0.68455 27.193
168 3PP0 03Q 0.000008518 0.51366 27.5148
169 4BTK DTQ 0.0000001747 0.50357 27.5964
170 5LPZ ADP 0.00000003229 0.66295 27.7108
171 5BVE 4VG 0.000000001427 0.47254 27.7778
172 4H3P ANP 0.000000001684 0.72185 28.0702
173 4H3Q ANP 0.00000007059 0.54218 28.0702
174 3C1X CKK 0.0004416 0.45994 28.0702
175 4E93 GUI 0.000001723 0.51168 28.655
176 4P5Z Q7M 0.00002774 0.44271 28.655
177 3BRN SRO 0.03552 0.40589 28.6624
178 3H9R TAK 0.000008942 0.58725 29.0909
179 4QTB 38Z 0.00000001616 0.59783 29.2398
180 5KO1 6UY 0.0000006753 0.60994 29.3286
181 3UIM ANP 0.00000002435 0.66858 29.4479
182 4Y85 499 0.0000007873 0.60681 29.8193
183 3E8N ATP 0.0000006234 0.46909 29.912
184 3E8N VRA 0.0000006234 0.46909 29.912
185 2QLU ADE 0.00001558 0.59541 29.9363
186 5LXC 7AA 0.0000000004469 0.55129 30.117
187 4KBA 1QM 0.0001223 0.46345 30.2115
188 5EOB 5QQ 0.00001618 0.519 30.4075
189 4CRL C1I 0.000003206 0.49527 30.4094
190 4CLI 5P8 0.000003406 0.53534 30.581
191 5NKB 8ZT 0.000007187 0.44625 30.719
192 3LXK MI1 0.0000005171 0.55698 30.8869
193 3GC8 B45 0.000003255 0.55208 30.9942
194 5LPB ADP 0.0000004822 0.64278 31.0811
195 3PLS ANP 0.00000000574 0.70705 31.2081
196 3KRL KRL 0.000004998 0.54404 31.3433
197 4YLL 4E3 0.00000004527 0.55357 31.5789
198 3VRY B43 0.00002646 0.49835 31.5789
199 3KMW ATP 0.00009005 0.51027 31.7343
200 3LXN MI1 0.000000004518 0.68402 31.761
201 5HX8 66P 0.00000003096 0.6115 32.1192
202 3SRV S19 0.0000000004111 0.56595 32.13
203 3NW7 LGV 0.00009776 0.47938 32.2476
204 4F4P 0SB 0.000001439 0.56685 32.6007
205 1VJY 460 0.0000004098 0.53424 32.6733
206 1JPA ANP 0.0000019 0.63248 32.6923
207 2H8H H8H 0.00000006611 0.64866 32.7485
208 1Y57 MPZ 0.0000000199 0.64016 32.7485
209 1OUK 084 0.000007964 0.56406 32.7485
210 4LOO SB4 0.00004525 0.42136 32.7485
211 1U5R ATP 0.000000004659 0.70155 32.7586
212 2PVF ACP 0.00000000009426 0.79076 32.9341
213 5X8I SQZ 0.0000000005277 0.74498 33.0409
214 2WU6 DKI 0.000000003473 0.67229 33.0409
215 1OPK P16 0.0001058 0.45245 33.0409
216 5MJA 7O3 0.00001135 0.42676 33.1148
217 3GQI ACP 0.000000002979 0.71047 33.1288
218 2OFV 242 0.00003806 0.44796 33.213
219 5T8O 76Z 0.0000008608 0.58355 33.2378
220 5C03 AGS 0.000002136 0.57937 33.3333
221 2OO8 RAJ 0.003682 0.42011 33.4385
222 4GJ3 0XP 0.0000001911 0.55428 33.4437
223 4K33 ACP 0.000000005069 0.55981 33.5385
224 5USZ SKE 0.000003708 0.52327 33.564
225 4Y93 746 0.000009922 0.51575 33.6257
226 4BKJ STI 0.002897 0.41505 33.6508
227 3EKK GS2 0.000002517 0.48249 33.8762
228 5EFQ ADP 0.000000007784 0.69132 33.9181
229 3BU5 ATP 0.00000001524 0.52921 33.9869
230 4ASE AV9 0.00005959 0.47575 34.2105
231 3SXS PP2 0.000008621 0.53945 34.3284
232 2Y6O 1N1 0.00003493 0.50755 34.3643
233 3KRR DQX 0.0000002165 0.60567 34.5763
234 3GNI ATP 0.0000001818 0.61331 34.7953
235 5UR1 YY9 0.00001423 0.50916 35.0482
236 3HMO STU 0.00000005204 0.66215 35.0877
237 3RI1 3RH 0.00000009758 0.55741 35.1438
238 4U0I 0LI 0.0008259 0.41936 35.2381
239 1BYG STU 0.00000002316 0.6882 35.2518
240 5JKG 6LF 0.00002265 0.49552 35.6913
241 5JFS 6K0 0.00001443 0.50614 35.7143
242 2XVD AS6 0.000008722 0.50418 35.7616
243 4WOV 3SM 0.00001933 0.55498 35.9621
244 4E1Z 0MX 0.0000001854 0.59908 36.0825
245 1U59 STU 0.0000000007232 0.7387 36.2369
246 4YMJ 4EJ 0.0000002018 0.69041 36.5132
247 4BHN BH9 0.00000002513 0.65118 36.5269
248 3E7O 35F 0.0001188 0.44452 36.5497
249 5TA6 79D 0.000007426 0.51139 36.5922
250 4EWH T77 0.0000003816 0.56218 36.7273
251 5U6C 7YS 0.000001191 0.57095 36.8254
252 4AG8 AXI 0.000002315 0.48603 37.0253
253 3IGO ANP 0.0000004289 0.59011 37.1345
254 3TTI KBI 0.0000005456 0.55607 37.4269
255 5EKO N17 0.0003987 0.41028 37.4269
256 4IDT T28 0.00000003375 0.67097 38.0117
257 3PTG 932 0.00000006027 0.4639 38.0117
258 4WHZ 3NL 0.00001741 0.41484 38.0117
259 5N87 N66 0.000000009401 0.56806 38.0192
260 5HES 032 0.000001203 0.48753 38.1107
261 5FBN 5WF 0.00002962 0.4864 38.3764
262 3ALN ANP 0.0000003884 0.59878 38.8379
263 2B9J ADP 0.0000000203 0.68132 38.8889
264 2B9I ADP 0.00000002695 0.66656 38.8889
265 2B9H ADP 0.00000003947 0.52882 38.8889
266 2B9F ADP 0.00000004145 0.51954 38.8889
267 5CEO 50D 0.00002139 0.43383 39
268 4AT3 LTI 0.00009096 0.46112 39.1304
269 3G5D 1N1 0.0000004609 0.5838 39.1608
270 5TO8 7FM 0.000008875 0.45639 39.3617
271 4CSV STI 0.0003358 0.46099 39.6364
272 3HZT J60 0.0000001286 0.6716 39.7661
273 3SXF BK5 0.0000007819 0.50982 39.7661
274 3SLS ANP 0.0000002199 0.60265 40.1316
275 5VC5 96M 0.0000004522 0.53711 40.1384
276 4QMN DB8 0.00000003325 0.55048 40.9677
277 2HK5 1BM 0.000008595 0.45958 41.1111
278 5BYZ 4WE 0.000000108 0.56375 41.5205
279 4TWP AXI 0.000006009 0.43492 41.6974
280 2X2M X2M 0.00000006015 0.53318 41.7197
281 4XLI 1N1 0.000008285 0.55887 41.791
282 4NM5 ADP 0.000000001369 0.68943 41.8129
283 2JLD AG1 0.000000000707 0.62392 41.8129
284 5JGA 6KC 0.000001708 0.51117 41.9048
285 3BZ3 YAM 0.000007601 0.40032 42.029
286 4NST ADP 0.00000002413 0.66876 42.1053
287 3F7Z 34O 0.000000006974 0.53757 42.1053
288 3ZRM ZRM 0.0000002258 0.49312 42.1053
289 1CM8 ANP 0.0000004438 0.4827 42.1053
290 2WEL K88 0.0000006859 0.41034 42.2018
291 4D2S DYK 0.0000007975 0.6229 42.2535
292 5H2U 1N1 0.0001291 0.49758 42.3221
293 5DA3 58V 0.000001706 0.61522 42.6415
294 1K3A ACP 0.0000004222 0.63645 42.8571
295 4I6H 1C8 0.00003294 0.52482 43.5065
296 2BPM 529 0.00000002454 0.48757 43.6893
297 1ZY5 ANP 0.00000001798 0.52018 43.8944
298 4BCM T7Z 0.0000003656 0.66931 44.5183
299 4BCQ TJF 0.0000002188 0.4624 44.5183
300 4CFU 2WC 0.000000008232 0.70973 44.5545
301 4BCN T9N 0.00000001827 0.70334 44.6667
302 5UOX 8GY 0.00000006541 0.6254 45.0185
303 5LMK 6ZK 0.000004194 0.4414 45.1178
304 2A19 ANP 0.000000004347 0.74549 45.4225
305 2F57 23D 0.000001225 0.60556 45.4259
306 2ZV2 609 0.00000004294 0.69554 45.6376
307 1UNH IXM 0.00000004863 0.68249 46.2329
308 3O0G 3O0 0.00000004766 0.50629 46.2329
309 5HQ0 LZ9 0.00000002526 0.65108 46.3576
310 4L9I 8PR 0.000000001887 0.72972 48.8304
311 4WNK 453 0.0000000008333 0.65291 49.7076
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