Receptor
PDB id Resolution Class Description Source Keywords
4F1M 2.04 Å EC: 2.7.11.1 CRYSTAL STRUCTURE OF THE G1179S ROCO4 KINASE DOMAIN BOUND TO FROM D. DISCOIDEUM. DICTYOSTELIUM DISCOIDEUM PROTEIN KINASE LRRK2 ROCO KINASE ATP-BINDING NUCLEOTIDESERINE/THREONINE-PROTEIN KINASE TRANSFERASE SIGNALING PRO
Ref.: ROCO KINASE STRUCTURES GIVE INSIGHTS INTO THE MECHA PARKINSON DISEASE-RELATED LEUCINE-RICH-REPEAT KINAS MUTATIONS. PROC.NATL.ACAD.SCI.USA V. 109 10322 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACP A:1301;
Valid;
none;
submit data
505.208 C11 H18 N5 O12 P3 c1nc(...
BTB A:1302;
Invalid;
none;
submit data
209.24 C8 H19 N O5 C(CO)...
MG A:1303;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4YZN 1.55 Å EC: 2.7.11.1 HUMANIZED ROCO4 BOUND TO COMPOUND 19 DICTYOSTELIUM DISCOIDEUM ROCO-PROTEIN KINASE LRRK2 INHIBITOR ROCO4 TRANSFERASE
Ref.: STRUCTURAL CHARACTERIZATION OF LRRK2 INHIBITORS. J.MED.CHEM. V. 58 3751 2015
Members (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 107 families.
1 4F1T - H52 C16 H21 N3 O2 S Cc1cncc2c1....
2 4YZN ic50 = 15.4 uM 4K5 C20 H21 F4 N5 O3 COc1cc(c(c....
3 4F1M - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
4 4F1O - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
5 4F0F - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 82 families.
1 4F1T - H52 C16 H21 N3 O2 S Cc1cncc2c1....
2 4YZN ic50 = 15.4 uM 4K5 C20 H21 F4 N5 O3 COc1cc(c(c....
3 4F1M - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
4 4F1O - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
5 4F0F - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 55 families.
1 4F1M - ACP C11 H18 N5 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ACP; Similar ligands found: 351
No: Ligand ECFP6 Tc MDL keys Tc
1 ACP 1 1
2 ACQ 0.866667 1
3 A2D 0.857143 0.945205
4 BA3 0.833333 0.945205
5 AP5 0.821918 0.945205
6 ADP 0.821918 0.972222
7 B4P 0.821918 0.945205
8 AN2 0.810811 0.958904
9 AP2 0.808219 0.986301
10 A12 0.808219 0.986301
11 M33 0.8 0.932432
12 ATP 0.789474 0.972222
13 5FA 0.779221 0.972222
14 AQP 0.779221 0.972222
15 AR6 0.779221 0.945205
16 APR 0.779221 0.945205
17 AGS 0.769231 0.921053
18 SAP 0.769231 0.921053
19 AD9 0.769231 0.945946
20 A 0.763889 0.944444
21 AMP 0.763889 0.944444
22 APC 0.75641 0.986301
23 CA0 0.753247 0.92
24 ADX 0.753247 0.851852
25 ANP 0.75 0.945946
26 50T 0.74359 0.932432
27 PRX 0.734177 0.87013
28 ABM 0.733333 0.893333
29 ATF 0.731707 0.933333
30 AMP MG 0.72 0.868421
31 SRA 0.706667 0.894737
32 A22 0.705882 0.958904
33 RBY 0.703704 0.959459
34 ADV 0.703704 0.959459
35 5AL 0.698795 0.906667
36 ADQ 0.689655 0.92
37 A1R 0.689655 0.909091
38 AU1 0.6875 0.945946
39 ADP MG 0.6875 0.881579
40 TAT 0.686747 0.933333
41 SRP 0.682353 0.907895
42 BEF ADP 0.679012 0.858974
43 ADP BEF 0.679012 0.858974
44 OAD 0.674157 0.92
45 4TC 0.673469 0.922078
46 4AD 0.670455 0.921053
47 AMO 0.670455 0.933333
48 00A 0.662921 0.860759
49 ADP PO3 0.662651 0.917808
50 3OD 0.659341 0.92
51 BIS 0.659341 0.909091
52 25A 0.659091 0.945205
53 8QN 0.659091 0.906667
54 5SV 0.659091 0.82716
55 OOB 0.659091 0.906667
56 ATP MG 0.654762 0.881579
57 SON 0.654321 0.933333
58 25L 0.652174 0.958904
59 PAJ 0.651685 0.8625
60 DLL 0.644444 0.906667
61 AHX 0.644444 0.897436
62 TXA 0.641304 0.907895
63 3UK 0.637363 0.894737
64 ADP ALF 0.632184 0.848101
65 ALF ADP 0.632184 0.848101
66 WAQ 0.630435 0.884615
67 LAD 0.630435 0.8625
68 PR8 0.630435 0.851852
69 MAP 0.629214 0.921053
70 GAP 0.627907 0.87013
71 ANP MG 0.625 0.871795
72 ADP VO4 0.625 0.906667
73 VO4 ADP 0.625 0.906667
74 ME8 0.623656 0.841463
75 PTJ 0.623656 0.873418
76 NB8 0.623656 0.897436
77 1ZZ 0.623656 0.819277
78 FYA 0.623656 0.906667
79 UP5 0.62 0.896104
80 G3A 0.618557 0.897436
81 AFH 0.612245 0.886076
82 G5P 0.612245 0.897436
83 9SN 0.610526 0.85
84 GTA 0.606061 0.864198
85 YAP 0.604167 0.896104
86 FA5 0.604167 0.907895
87 TXD 0.60396 0.884615
88 XAH 0.597938 0.841463
89 XYA 0.597222 0.821918
90 ADN 0.597222 0.821918
91 RAB 0.597222 0.821918
92 48N 0.594059 0.897436
93 DAL AMP 0.593407 0.881579
94 2A5 0.593023 0.92
95 AOC 0.592593 0.8
96 4UV 0.591837 0.871795
97 NAI 0.588235 0.884615
98 NXX 0.588235 0.907895
99 NAX 0.588235 0.875
100 DND 0.588235 0.907895
101 6V0 0.588235 0.873418
102 ATR 0.586207 0.944444
103 PAP 0.586207 0.958333
104 ADP BMA 0.585106 0.894737
105 LAQ 0.584158 0.819277
106 5AS 0.583333 0.761364
107 TXE 0.582524 0.884615
108 OMR 0.582524 0.831325
109 5N5 0.581081 0.797297
110 4UU 0.58 0.871795
111 A A 0.578947 0.918919
112 7D3 0.578313 0.881579
113 AP0 0.576923 0.873418
114 A4D 0.573333 0.797297
115 5CD 0.573333 0.783784
116 JB6 0.572917 0.884615
117 4UW 0.572816 0.839506
118 A4P 0.571429 0.823529
119 CNA 0.570093 0.907895
120 7D4 0.569767 0.881579
121 ITT 0.569767 0.917808
122 A2R 0.565217 0.958904
123 M2T 0.564103 0.716049
124 YLP 0.563107 0.821429
125 139 0.560748 0.851852
126 ADJ 0.560748 0.831325
127 T5A 0.560748 0.843373
128 TAD 0.558824 0.910256
129 ATP A A A 0.555556 0.905405
130 A3P 0.552941 0.944444
131 TYM 0.552381 0.907895
132 IOT 0.551402 0.833333
133 EP4 0.551282 0.734177
134 MYR AMP 0.55102 0.797619
135 7D5 0.55 0.855263
136 A3D 0.54955 0.894737
137 GCP 0.548387 0.922078
138 YLC 0.54717 0.841463
139 YLB 0.54717 0.821429
140 UPA 0.54717 0.884615
141 NAD 0.545455 0.906667
142 COD 0.545455 0.813953
143 G5A 0.544444 0.781609
144 DTA 0.544304 0.766234
145 3DH 0.54321 0.753247
146 DZD 0.540541 0.910256
147 AHZ 0.538462 0.797619
148 MTA 0.5375 0.753247
149 3AM 0.536585 0.90411
150 A2P 0.534884 0.930556
151 TYR AMP 0.534653 0.858974
152 AR6 AR6 0.533981 0.893333
153 6AD 0.532609 0.886076
154 PPS 0.532609 0.851852
155 YLA 0.53211 0.821429
156 AMP DBH 0.529412 0.87013
157 AYB 0.527273 0.811765
158 A5A 0.526882 0.788235
159 TSB 0.526316 0.8
160 6RE 0.52381 0.7625
161 S4M 0.523256 0.670455
162 SSA 0.521277 0.802326
163 NA7 0.520408 0.959459
164 7MD 0.519231 0.864198
165 LPA AMP 0.518868 0.797619
166 BTX 0.517857 0.843373
167 NAE 0.517241 0.871795
168 52H 0.515789 0.761364
169 54H 0.515789 0.770115
170 VMS 0.515789 0.770115
171 BT5 0.513274 0.833333
172 NAQ 0.512821 0.85
173 ZAS 0.511905 0.746835
174 J7C 0.511628 0.772152
175 A3N 0.511628 0.766234
176 IMO 0.511628 0.90411
177 AV2 0.510638 0.893333
178 53H 0.510417 0.761364
179 5CA 0.510417 0.802326
180 ARU 0.510204 0.839506
181 ARG AMP 0.509434 0.831325
182 ALF ADP 3PG 0.509259 0.839506
183 AF3 ADP 3PG 0.509259 0.839506
184 LA8 ALF 3PG 0.509259 0.839506
185 M24 0.508621 0.829268
186 ZID 0.508475 0.894737
187 2AM 0.506024 0.917808
188 V3L 0.505376 0.945205
189 3AT 0.505376 0.972222
190 AVV 0.505155 0.897436
191 MAO 0.5 0.761905
192 LSS 0.5 0.764045
193 NSS 0.5 0.802326
194 DSZ 0.5 0.802326
195 EAD 0.5 0.851852
196 DSH 0.5 0.728395
197 P5A 0.5 0.747253
198 YLY 0.495726 0.811765
199 NVA LMS 0.494949 0.744444
200 5X8 0.494505 0.766234
201 DAT 0.494505 0.906667
202 7MC 0.490909 0.843373
203 LEU LMS 0.49 0.744444
204 SMM 0.489583 0.689655
205 SAM 0.489362 0.694118
206 DTP 0.489362 0.906667
207 7DD 0.488889 0.958333
208 GJV 0.488636 0.753086
209 OVE 0.488372 0.881579
210 5AD 0.486842 0.726027
211 KAA 0.485149 0.755556
212 GSU 0.485149 0.781609
213 P1H 0.483871 0.831325
214 NDE 0.483871 0.907895
215 N0B 0.483333 0.821429
216 A3G 0.482759 0.802632
217 NAD IBO 0.482456 0.848101
218 NAJ PZO 0.478632 0.82716
219 4TA 0.478261 0.809524
220 SFG 0.478261 0.753247
221 YSA 0.47619 0.781609
222 FB0 0.47619 0.827586
223 NDC 0.47619 0.85
224 7DT 0.473118 0.958333
225 A7D 0.472527 0.779221
226 NJP 0.469565 0.921053
227 FDA 0.46875 0.835294
228 A5D 0.468085 0.766234
229 SA8 0.468085 0.710843
230 MHZ 0.467391 0.701149
231 71V 0.466667 0.884615
232 0WD 0.465517 0.897436
233 G A A A 0.465517 0.85
234 6FA 0.465116 0.843373
235 GGZ 0.464646 0.804878
236 SAH 0.463158 0.746835
237 6C6 0.463158 0.883117
238 SAI 0.463158 0.7375
239 NAJ PYZ 0.46281 0.829268
240 Y3J 0.4625 0.706667
241 7D7 0.461538 0.723684
242 TXP 0.46087 0.897436
243 PO4 PO4 A A A A PO4 0.460784 0.878378
244 S7M 0.459184 0.694118
245 AMP NAD 0.459016 0.858974
246 6IA 0.458333 0.839506
247 DDS 0.458333 0.855263
248 FAD 0.458015 0.853659
249 SFD 0.458015 0.736842
250 FAS 0.458015 0.853659
251 ODP 0.456897 0.886076
252 A3S 0.456522 0.813333
253 7C5 0.453704 0.797468
254 AAT 0.453608 0.710843
255 EEM 0.453608 0.694118
256 RGT 0.45283 0.933333
257 NPW 0.452174 0.8875
258 NDP 0.452174 0.897436
259 FAY 0.451852 0.864198
260 PGS 0.451613 0.860759
261 D5M 0.449438 0.88
262 DA 0.449438 0.88
263 NEC 0.449438 0.727273
264 U A G G 0.449153 0.860759
265 2SA 0.44898 0.933333
266 NIA 0.448276 0.802469
267 NZQ 0.448276 0.910256
268 A U 0.447368 0.848101
269 A3T 0.446809 0.8
270 A A A 0.446602 0.906667
271 128 0.446429 0.758621
272 6K6 0.445545 0.905405
273 GEK 0.445545 0.740741
274 4YB 0.445455 0.764045
275 AAM 0.444444 0.944444
276 FNK 0.444444 0.806818
277 62F 0.444444 0.864198
278 Z5A 0.443548 0.761364
279 WSA 0.442478 0.790698
280 AMZ 0.44186 0.891892
281 C2R 0.44186 0.88
282 12D 0.441441 0.767442
283 XNP 0.440678 0.851852
284 RFL 0.437956 0.823529
285 N6P 0.436893 0.890411
286 62X 0.436893 0.670455
287 AIR 0.433735 0.876712
288 PLP AAD 0.433333 0.725275
289 GP3 0.43299 0.897436
290 A6D 0.432692 0.705882
291 V1N 0.431193 0.893333
292 649 0.429825 0.747253
293 GP2 0.428571 0.910256
294 NA0 0.428571 0.907895
295 GDP 0.428571 0.896104
296 0UM 0.427184 0.702381
297 DCA 0.42623 0.825581
298 ETB 0.42623 0.835294
299 GNH 0.424242 0.884615
300 NAP 0.424 0.92
301 PUA 0.422764 0.8625
302 APU 0.422414 0.871795
303 101 0.422222 0.855263
304 3AD 0.421687 0.808219
305 FA9 0.42069 0.865854
306 TAP 0.420635 0.884615
307 TM1 0.420561 0.755814
308 P5F 0.41958 0.825581
309 0T1 0.419355 0.825581
310 COA 0.419355 0.825581
311 K15 0.419048 0.686047
312 7RP 0.417582 0.902778
313 S8M 0.417476 0.7625
314 NHD 0.416667 0.881579
315 GTP 0.415842 0.896104
316 FCX 0.414062 0.797753
317 F2N 0.413793 0.816092
318 AS 0.413043 0.835443
319 7RA 0.413043 0.931507
320 G1R 0.411765 0.884615
321 SXZ 0.411215 0.714286
322 QQY 0.411111 0.794872
323 ACK 0.411111 0.837838
324 AMX 0.409449 0.835294
325 30N 0.409449 0.755319
326 CAO 0.409449 0.797753
327 J7V 0.409449 0.813953
328 COS 0.409449 0.806818
329 1DG 0.409449 0.897436
330 DG1 0.409449 0.897436
331 NAD BBN 0.408759 0.821429
332 8BR 0.408602 0.883117
333 GNP 0.407767 0.873418
334 GSP 0.407767 0.851852
335 D3Y 0.407767 0.792208
336 G2P 0.407767 0.910256
337 CC5 0.407407 0.819444
338 KB1 0.407407 0.702381
339 N01 0.406504 0.881579
340 CMX 0.40625 0.825581
341 SCO 0.40625 0.825581
342 CMP 0.404255 0.876712
343 2BA 0.404255 0.890411
344 ACO 0.403101 0.797753
345 FAM 0.403101 0.806818
346 NAD CJ3 0.402878 0.793103
347 2VA 0.402062 0.779221
348 3NZ 0.401869 0.78481
349 26A 0.4 0.74359
350 HAX 0.4 0.806818
351 QQX 0.4 0.78481
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4YZN; Ligand: 4K5; Similar sites found: 244
This union binding pocket(no: 1) in the query (biounit: 4yzn.bio1) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3KA2 2NC 0.005175 0.43064 None
2 5I35 ANP 0.00000007039 0.64063 1.74216
3 3KAL ADP 0.0009527 0.44608 1.74216
4 4RDL FUC GAL NDG FUC 0.01588 0.418 1.74216
5 4CC6 L5Y 0.01635 0.41068 1.74216
6 1SGJ OAA 0.01088 0.40005 1.76056
7 1W2D ADP 0.0002049 0.49985 1.88679
8 1W2D 4IP 0.0004986 0.41571 1.88679
9 2W5P CL8 0.02382 0.41091 2.01342
10 3DGY 2GP 0.007328 0.43608 2.06186
11 4CYI ATP 0.00001832 0.48939 2.09059
12 1I7L ATP 0.0007999 0.4367 2.09059
13 4PU5 ANP 0.001259 0.42674 2.09059
14 5C1P DAL DAL 0.004799 0.40612 2.09059
15 4AVB CMP 0.01743 0.4014 2.09059
16 5C1P ADP 0.001033 0.40001 2.09059
17 5IQD GNP 0.00002292 0.52033 2.43902
18 5IQD RIO 0.00002479 0.52033 2.43902
19 4LH7 1X8 0.000899 0.47973 2.43902
20 5IGI GMP 0.0003429 0.46929 2.43902
21 5IGI ZIT 0.0003673 0.46929 2.43902
22 2AQX ATP 0.0004485 0.44917 2.43902
23 2CFM AMP 0.003582 0.439 2.43902
24 1T36 ADP 0.005578 0.40641 2.43902
25 2QX0 PH2 0.003114 0.4548 2.51572
26 1TZD ADP 0.0001568 0.52003 2.54545
27 4FE2 ADP 0.002085 0.44561 2.78746
28 2G50 PYR 0.006722 0.43965 2.78746
29 2IF8 ADP 0.00004188 0.42889 2.78746
30 5TT6 ATP 0.001476 0.42747 2.78746
31 1YFS ALA 0.01696 0.4078 2.78746
32 5COU ATP 0.001133 0.4058 2.78746
33 4B1L FRU 0.01721 0.40792 3.0303
34 5W2I I3P 0.0001227 0.47037 3.11284
35 5W2I ADP 0.0001227 0.47037 3.11284
36 5MW8 ATP 0.00000218 0.54026 3.13589
37 4OCJ NDG 0.0000574 0.50444 3.13589
38 4OCV ANP 0.00006948 0.49308 3.13589
39 1CKM GTP 0.007155 0.4288 3.13589
40 2Z49 AMG 0.01963 0.40484 3.13589
41 4O4F ATP 0.0008174 0.42355 3.22581
42 4O4F IHP 0.0008985 0.41691 3.22581
43 3PDT ADP 0.000002739 0.49641 3.27273
44 4R78 AMP 0.00007703 0.52765 3.48432
45 3HAV ATP 0.0002112 0.51503 3.48432
46 4ANW O92 0.00008249 0.42997 3.48432
47 3BEO UDP 0.006197 0.415 3.48432
48 5NCY 8TK 0.000612 0.40954 3.48432
49 3VPB ADP 0.0000491 0.48887 3.5461
50 3VPC ADP 0.0001179 0.4735 3.5461
51 4CS9 AMP 0.0031 0.44357 3.7037
52 2IO8 ADP 0.0001234 0.46121 3.83275
53 4U98 ACP 0.000889 0.45352 3.83275
54 3HQP OXL 0.006202 0.44089 3.83275
55 2VPQ ANP 0.001024 0.43044 3.83275
56 2YW2 ATP 0.005271 0.40751 3.83275
57 3W0O ADP 0.00003163 0.45168 4.01146
58 3W0O HY0 0.00003163 0.45168 4.01146
59 1UPR 4IP 0.02243 0.41049 4.06504
60 4IX4 ADP 0.000002294 0.52649 4.18118
61 3ZJX BOG 0.001837 0.46724 4.18118
62 5VZ0 ADP 0.0007033 0.41612 4.18118
63 1GSA ADP 0.01497 0.4089 4.18118
64 1M0W ANP 0.0009495 0.40748 4.18118
65 3HP9 CF1 0.02778 0.40475 4.18118
66 4Z4P SAH 0.006517 0.414 4.21687
67 4ZS4 ATP 0.00000201 0.56029 4.52962
68 2V58 LZJ 0.004507 0.42798 4.52962
69 5FS0 5JC 0.01508 0.41246 4.73934
70 4XYM A12 0.002366 0.40457 4.78261
71 3WVR AMP 0.0007596 0.46147 4.87805
72 1NY5 ADP 0.004099 0.41935 4.87805
73 2H92 C5P 0.01835 0.40032 5.02283
74 3UDZ ADP 0.000003821 0.51038 5.07099
75 5K2M ADP 0.0004644 0.44647 5.12821
76 1PK8 ATP 0.0007604 0.42546 5.21327
77 2PYW ADP 0.000003788 0.51814 5.22648
78 3TII ANP 0.00229 0.44852 5.22648
79 2QK4 ATP 0.0003473 0.40698 5.22648
80 3WUR O4B 0.01151 0.41571 5.26316
81 1TQP ATP 0.000003342 0.52389 5.31915
82 1ZP9 ATP 0.000003532 0.57032 5.42636
83 1ZTH ADP 0.0000009389 0.49448 5.42636
84 4OAV ACP 0.000000006237 0.68864 5.57491
85 4AZW ATP 0.000009954 0.50107 5.57491
86 4AZT LY2 0.001259 0.46125 5.57491
87 2YRX AMP 0.004295 0.44707 5.57491
88 4OUJ LBT 0.01269 0.41337 5.57491
89 3ETH ATP 0.003233 0.40666 5.57491
90 2PA7 TYD 0.03307 0.40088 5.67376
91 5KBE IPH 0.01341 0.41953 5.67686
92 3TM0 ANP 0.0002434 0.4133 5.70342
93 3TM0 B31 0.0002637 0.40785 5.70342
94 3TDV GDP 0.000001834 0.56886 5.92335
95 2VQD AP2 0.0009456 0.43947 5.92335
96 1EHI ADP 0.001465 0.43523 5.92335
97 1VRP IOM 0.01626 0.40767 5.92335
98 2DTJ THR 0.01989 0.40239 6.17978
99 4WW7 AMP 0.000003769 0.52369 6.51341
100 4GYI ADP 0.000004978 0.57089 6.62021
101 5ENZ UDP 0.008006 0.40634 6.62021
102 3A76 SPD 0.02533 0.40563 6.81818
103 3X01 AMP 0.00005709 0.54592 6.96864
104 2BKK ADP 0.00006386 0.51795 7.10059
105 4KU7 PCG 0.006974 0.42051 7.18954
106 3DNT ATP 0.00131 0.42141 7.31707
107 2PUL ACP 0.004438 0.42318 8.01394
108 4XMF HSM 0.01083 0.42387 8.15217
109 3AB4 THR 0.02187 0.40034 8.36237
110 1IA9 ANP 0.000009003 0.53185 9.28571
111 3VOT ADP 0.0006545 0.47516 9.40767
112 3KDM TES 0.01579 0.41451 9.63303
113 2OVD DAO 0.02552 0.40734 10.4396
114 4RQL SNE 0.01535 0.41206 10.453
115 5LXT ACP 0.001923 0.41918 10.4895
116 3SJK LYS PRO VAL LEU ARG THR ALA 0.01665 0.41985 11.0526
117 4O1P ANP 0.00000001013 0.59945 11.1498
118 5TDF ADP 0.0006874 0.43097 11.4983
119 2GQS ADP 0.0006272 0.46043 12.2363
120 2BVE PH5 0.03715 0.40634 12.605
121 5X8I SQZ 0.000000001835 0.70273 12.892
122 4DFU QUE 0.00275 0.4551 12.892
123 2WU6 DKI 0.000000001207 0.67411 13.2404
124 5C4L 4XR 0.000003977 0.54457 13.2404
125 5C4L SIS 0.00004869 0.49826 13.2404
126 3I0O ADP 0.0001364 0.50849 16.0279
127 5CKW ANP 0.000000965 0.4943 16.7247
128 4Q5H ANP 0.000000716 0.58709 17.9487
129 1CBK ROI 0.011 0.42464 20
130 5MY8 RXZ 0.000000625 0.56763 22.2997
131 3GNI ATP 0.000000002105 0.68131 25.4355
132 2B9I ADP 0.00000001538 0.66152 25.784
133 2B9J ADP 0.00000001096 0.59152 25.784
134 2B9H ADP 0.00000003407 0.5908 25.784
135 5GZ9 ANP 0.00000001307 0.63158 29.9652
136 3TTI KBI 0.00000002773 0.57582 30.3136
137 3PTG 932 0.000000003791 0.56041 30.3136
138 4WHZ 3NL 0.00000008158 0.45117 30.3136
139 5LXC 7AA 0.00000000007182 0.65021 30.662
140 2CSN CKI 0.00003152 0.53605 30.662
141 4QTB 38Z 0.00000001021 0.64994 31.0105
142 3GC0 AMP 0.000000169 0.64107 31.0105
143 4UX9 ANP 0.0000000005154 0.70745 31.3589
144 1CM8 ANP 0.00000005553 0.56693 31.3589
145 2B9F ADP 0.00000002067 0.59051 32.0557
146 4NST ADP 0.00000001102 0.66798 32.4042
147 4NST AF3 0.0000001304 0.65931 32.4042
148 5EFQ ADP 0.000000006119 0.60863 32.4042
149 4IZY 1J2 0.0000004106 0.58333 32.4042
150 1UNH IXM 0.0000000007595 0.7532 32.7526
151 5BVE 4VG 0.0000000009037 0.74827 32.7526
152 4H3P ANP 0.000000002334 0.69807 32.7526
153 3O0G 3O0 0.00000000211 0.61193 32.7526
154 4AU8 Z3R 0.00000008472 0.53308 32.7526
155 3E7O 35F 0.000001104 0.48337 32.7526
156 4H3Q ANP 0.000000002689 0.65981 33.101
157 1OUK 084 0.00001067 0.58635 33.4495
158 4LOO SB4 0.000002274 0.51052 33.4495
159 4CFU 2WC 0.0000000004127 0.75383 33.7979
160 4BCN T9N 0.000000001827 0.735 33.7979
161 4WNK 453 0.000000001626 0.68626 33.7979
162 4BCM T7Z 0.0000002756 0.66119 33.7979
163 3GC8 B45 0.0000001833 0.59123 33.7979
164 4BCQ TJF 0.00000003344 0.54207 33.7979
165 5LMK 6ZK 0.0000001459 0.53867 33.7979
166 5EKO N17 0.0003703 0.4486 33.7979
167 2XMY CDK 0.00000001314 0.69845 34.1463
168 5HQ0 LZ9 0.000000003438 0.67219 34.1463
169 4AUA 4AU 0.00000005402 0.56742 34.1463
170 2BPM 529 0.000000000126 0.50824 34.1463
171 1V0O INR 0.0000000007455 0.71016 34.8432
172 2GU8 796 0.0000000001816 0.77269 35.1916
173 1RE8 BD2 0.000000001285 0.7208 35.1916
174 2QCS ANP 0.0000000005359 0.69815 35.1916
175 3IDB ANP 0.0000000003597 0.69572 35.1916
176 3FHI ANP 0.0000000008319 0.69017 35.1916
177 2VN9 GVD 0.000000000011 0.62543 35.1916
178 2WEL K88 0.0000000295 0.49993 35.1916
179 5C03 AGS 0.0000002778 0.60544 35.5401
180 4WOV 3SM 0.000001829 0.59167 35.5401
181 4WB7 ATP 0.000000003259 0.543 35.5401
182 4WB6 ATP 0.0000000005606 0.69733 36.2369
183 5T8O 76Z 0.0000001541 0.60154 36.2369
184 4CRL C1I 0.0000001772 0.5026 36.2369
185 1XJD STU 0.0000000001168 0.74533 36.5854
186 3E8N ATP 0.000000004694 0.49413 36.5854
187 3E8N VRA 0.000000004694 0.49413 36.5854
188 5AWM ANP 0.0000000873 0.66481 37.2822
189 4YLL 4E3 0.00000001303 0.63165 37.2822
190 4BTK DTQ 0.00000008436 0.56786 37.2822
191 3HZT J60 0.000000004831 0.72633 37.9791
192 4OTH DRN 0.0000000004027 0.70267 37.9791
193 4IDT T28 0.000000000787 0.63032 37.9791
194 2JLD AG1 0.000000000262 0.72776 38.3275
195 3F7Z 34O 0.000000001135 0.63436 38.3275
196 5BYZ 4WE 0.0000001794 0.60186 38.3275
197 4NM5 ADP 0.00000008679 0.5978 38.3275
198 3ZRM ZRM 0.0000001321 0.55877 38.3275
199 3SXF BK5 0.0000004236 0.48666 38.676
200 2VZ6 FEF 0.0000000006928 0.75511 38.9776
201 4XH0 ADP 0.00000006225 0.70238 39.3728
202 1ZY5 ANP 0.000001005 0.51687 39.7213
203 4BHN BH9 0.000000000299 0.71757 40.0697
204 3HMO STU 0.00000000292 0.60684 40.0697
205 5KO1 6UY 0.0000002662 0.61427 40.2827
206 5N87 N66 0.00000001213 0.66056 40.4181
207 5TA6 79D 0.00000001134 0.58893 40.4181
208 4KBA 1QM 0.000003328 0.49998 40.4181
209 2A19 ANP 0.0000000009096 0.76182 40.493
210 4D2S DYK 0.00000002338 0.55073 40.493
211 4Y85 499 0.0000004042 0.53358 40.7666
212 4I6H 1C8 0.00000003845 0.64377 41.115
213 2V7O DRN 0.00000000003361 0.61407 41.115
214 1PHK ATP 0.0000000000222 0.70975 41.4634
215 5LPB ADP 0.00000006694 0.53449 41.4634
216 4YZC STU 0.00000000102 0.70933 41.8118
217 5LPZ ADP 0.000000001947 0.70158 41.8118
218 5UOX 8GY 0.0000000004461 0.70081 42.4354
219 4L9I 8PR 0.0000002795 0.61331 42.5087
220 3TXO 07U 0.000000003895 0.59281 42.5087
221 5USZ SKE 0.00000000755 0.59649 43.2056
222 2QLU ADE 0.0000002993 0.66439 43.9024
223 3ALN ANP 0.00000001502 0.61358 43.9024
224 3IGO ANP 0.0000000342 0.6218 44.2509
225 2WEI VGG 0.0000008403 0.59942 44.2509
226 1VJY 460 0.0000000001731 0.73291 44.5993
227 5VC5 96M 0.000000001924 0.67779 44.5993
228 4FG8 ATP 0.000000009929 0.6205 45.2962
229 5DBX ANP 0.0000001284 0.52515 45.2962
230 2ZV2 609 0.0000000001065 0.8074 45.6446
231 5LI1 ANP 0.0000000002409 0.6918 45.6446
232 5LI9 ACP 0.000000005679 0.67164 45.6446
233 5UKL SIX 0.0000002705 0.5876 46.3415
234 3PVW QRX 0.00000002231 0.5874 46.3415
235 4FL3 ANP 0.0000000009901 0.66792 46.6899
236 4DC2 ADE 0.000000002172 0.50343 47.3868
237 2PVF ACP 0.0000000008736 0.72759 47.7352
238 3UIM ANP 0.00000000391 0.68807 47.7352
239 3GQI ACP 0.00000001016 0.66957 48.0836
240 3SRV S19 0.00000000002858 0.67868 48.3755
241 3H9R TAK 0.00000002771 0.70051 48.4321
242 3PP0 03Q 0.0000003667 0.54396 48.7805
243 3BU5 ATP 0.00000000008136 0.67522 49.1289
244 3KMW ATP 0.00007391 0.45251 49.8155
Feedback