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Receptor
PDB id Resolution Class Description Source Keywords
4F2Q 2.2 Å NON-ENZYME: SIGNAL_HORMONE QUISQUALATE BOUND TO THE D655A MUTANT OF THE LIGAND BINDING GLUA3 RATTUS NORVEGICUS GLUTAMATE RECEPTOR GLUA3 GLUR3 AMPA RECEPTOR S1S2 LBD NEUROTRANSMITTER RECEPTOR QUISQUALATE TRANSPORT PROTEIN-ACOMPLEX
Ref.: THE LOSS OF AN ELECTROSTATIC CONTACT UNIQUE TO AMPA LIGAND BINDING DOMAIN 2 SLOWS CHANNEL ACTIVATION. BIOCHEMISTRY V. 51 4015 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
QUS A:301;
Valid;
none;
Ki = 0.042 uM
189.126 C5 H7 N3 O5 C([C@...
ZN A:302;
Part of Protein;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4F2Q 2.2 Å NON-ENZYME: SIGNAL_HORMONE QUISQUALATE BOUND TO THE D655A MUTANT OF THE LIGAND BINDING GLUA3 RATTUS NORVEGICUS GLUTAMATE RECEPTOR GLUA3 GLUR3 AMPA RECEPTOR S1S2 LBD NEUROTRANSMITTER RECEPTOR QUISQUALATE TRANSPORT PROTEIN-ACOMPLEX
Ref.: THE LOSS OF AN ELECTROSTATIC CONTACT UNIQUE TO AMPA LIGAND BINDING DOMAIN 2 SLOWS CHANNEL ACTIVATION. BIOCHEMISTRY V. 51 4015 2012
Members (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 286 families.
1 4F2O Ki = 0.042 uM QUS C5 H7 N3 O5 C([C@@H](C....
2 3DP4 Kd = 43 nM AMQ C7 H10 N2 O4 Cc1c(c(no1....
3 4F22 Ki = 30.26 uM KAI C10 H15 N O4 CC(=C)[C@H....
4 4F3B Ki = 1.271 uM GLU C5 H9 N O4 C(CC(=O)O)....
5 4F2Q Ki = 0.042 uM QUS C5 H7 N3 O5 C([C@@H](C....
6 3RT8 - CWD C7 H8 Cl N3 O4 C1=C(C(=O)....
7 3M3F - P99 C16 H16 F2 N2 O4 S2 c1ccc(cc1)....
8 3LSX - PZI C6 H10 N2 O2 C1CC(=O)N(....
9 3LSW - GLU C5 H9 N O4 C(CC(=O)O)....
70% Homology Family (233)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 209 families.
1 4O3B Ki = 0.82 uM GLU C5 H9 N O4 C(CC(=O)O)....
2 5CBS Kd = 3.9 uM E42 C15 H15 N O3 c1cc(cc(c1....
3 3PD8 Ki = 108 nM HA7 C7 H8 N2 O4 C1CN[C@@H]....
4 1P1O Kd = 1.74 uM QUS C5 H7 N3 O5 C([C@@H](C....
5 1MQH ic50 = 0.3 uM BWD C7 H8 Br N3 O4 C1=C(C(=O)....
6 1FTK ic50 = 14.5 uM KAI C10 H15 N O4 CC(=C)[C@H....
7 3TKD - CYZ C14 H16 Cl N3 O4 S2 c1c2c(cc(c....
8 1M5F ic50 = 14.8 nM AM1 C8 H10 N2 O5 Cc1c(c(no1....
9 5FTI - GLU C5 H9 N O4 C(CC(=O)O)....
10 1XHY Ki = 624 nM KAI C10 H15 N O4 CC(=C)[C@H....
11 1M5C ic50 = 0.5 uM BRH C6 H7 Br N2 O4 C(c1c(c(no....
12 1SYI Ki = 3330 nM CPW C10 H13 N3 O4 C1CC2=C(C1....
13 5O9A - 7M6 C9 H10 Cl F N2 O2 S c1cc2c(cc1....
14 1MY3 - BWD C7 H8 Br N3 O4 C1=C(C(=O)....
15 3ILU - HFZ C8 H8 F3 N3 O4 S2 c1c(c(cc2c....
16 3PMV - 557 C17 H22 F3 N3 O3 S C[C@H](CNS....
17 5H8S - 5YC C15 H16 N4 O S CCN(CC1=CC....
18 2XHD - GLU C5 H9 N O4 C(CC(=O)O)....
19 3B7D - CNI C9 H2 N4 O4 C1=C(C(=CC....
20 4U1Z - KAI C10 H15 N O4 CC(=C)[C@H....
21 1WVJ Ki = 185 nM IBC C11 H14 N2 O4 C1CC=C(c2c....
22 1P1U - AMQ C7 H10 N2 O4 Cc1c(c(no1....
23 4Q30 - NWD C7 H8 N4 O6 C1=C(C(=O)....
24 4U23 - FWD C7 H8 F N3 O4 C1=C(C(=O)....
25 1MQG ic50 = 0.52 uM IWD C7 H8 I N3 O4 C1=C(C(=O)....
26 3BBR - BHY C20 H28 N2 O4 S2 C[C@@H](CN....
27 3LSF - PZI C6 H10 N2 O2 C1CC(=O)N(....
28 3PMX - 808 C18 H20 F3 N O3 S CC(C)S(=O)....
29 2ANJ - KAI C10 H15 N O4 CC(=C)[C@H....
30 2XX8 - 1NE C17 H18 F3 N3 O CN(C)C(=O)....
31 1P1Q Kd = 12.8 uM AMQ C7 H10 N2 O4 Cc1c(c(no1....
32 2AL5 - FWD C7 H8 F N3 O4 C1=C(C(=O)....
33 5YBG ic50 = 0.03 uM 8SO C21 H30 N2 O4 S2 C[C@@H](CN....
34 1M5E ic50 = 20.1 nM AM1 C8 H10 N2 O5 Cc1c(c(no1....
35 3BKI ic50 = 7.6 uM FQX C8 H4 N4 O4 c1c2c(cc3c....
36 2AIX - U1K C10 H16 N2 O3 S CC(C)(C)c1....
37 3B6W - GLU C5 H9 N O4 C(CC(=O)O)....
38 2I3W - GLU C5 H9 N O4 C(CC(=O)O)....
39 3O6H - O25 C18 H22 F3 N5 O2 S CCNCc1cn(n....
40 3KGC - ZK1 C14 H15 F3 N3 O6 P c1c(c(cc2c....
41 3BFU Ki = 531 nM R2P C5 H7 N3 O3 S C(c1c(nsn1....
42 3UA8 ic50 = 14 nM 08W C15 H13 F3 N6 O5 S CNC(=O)c1c....
43 4LZ7 - GLU C5 H9 N O4 C(CC(=O)O)....
44 1FTL ic50 = 998 nM DNQ C8 H2 N4 O6 C1=C(C(=CC....
45 3B6Q - GLU C5 H9 N O4 C(CC(=O)O)....
46 3RN8 - RN8 C22 H16 N2 O4 S2 CCc1c(c(c(....
47 1P1W - AMQ C7 H10 N2 O4 Cc1c(c(no1....
48 1MQI ic50 = 23.53 nM FWD C7 H8 F N3 O4 C1=C(C(=O)....
49 3O29 - O29 C23 H30 F3 N5 O2 S CN(C)CCNC(....
50 1FTJ ic50 = 821 nM GLU C5 H9 N O4 C(CC(=O)O)....
51 3PD9 Ki = 494 nM HA5 C7 H8 N2 O4 C1c2c(onc2....
52 1M5B ic50 = 9.7 nM BN1 C8 H10 N6 O4 Cn1nc(nn1)....
53 3EN3 - KAI C10 H15 N O4 CC(=C)[C@H....
54 1SYH Ki = 393 nM CPW C10 H13 N3 O4 C1CC2=C(C1....
55 4X48 - XPF C18 H20 N2 O4 S2 CC(C)S(=O)....
56 3H6W - NS7 C19 H29 N3 O4 S2 Cc1cc2c(cc....
57 1MY4 - IWD C7 H8 I N3 O4 C1=C(C(=O)....
58 4IGT Ki = 40.8 uM 3ZA C9 H16 N2 O6 CN(C(=O)CC....
59 3M3L - P99 C16 H16 F2 N2 O4 S2 c1ccc(cc1)....
60 5CBR Kd = 1.8 uM 4ZK C14 H12 Cl2 N2 O3 c1c(cc(c(c....
61 4GXS - 0YS C18 H21 Cl2 N3 O9 c1c(cc(c(c....
62 4U21 - FWF C24 H36 N2 O4 S2 C[C@@H](CN....
63 4YMA - 4E5 C12 H13 N O5 c1c(cc(cc1....
64 1FW0 - KAI C10 H15 N O4 CC(=C)[C@H....
65 1LB8 - AMQ C7 H10 N2 O4 Cc1c(c(no1....
66 3FAS Ki = 171 nM GLU C5 H9 N O4 C(CC(=O)O)....
67 4U22 - FWD C7 H8 F N3 O4 C1=C(C(=O)....
68 4ISU Ki = 0.21 mM IKM C12 H14 N2 O6 C1C=C[C@H]....
69 1MXU ic50 = 4 uM BWD C7 H8 Br N3 O4 C1=C(C(=O)....
70 4U4X Kd = 9.8 uM 3C2 C8 H11 N3 O2 S CCN1CNS(=O....
71 1MM7 ic50 = 20 nM QUS C5 H7 N3 O5 C([C@@H](C....
72 2XX9 - 1NF C19 H19 F4 N3 O c1cc(c(cc1....
73 3M3K - GLU C5 H9 N O4 C(CC(=O)O)....
74 2XXH - 1NG C20 H22 F3 N3 O c1cc(ccc1C....
75 5FHM - 5XP C15 H17 N7 O4 c1cc(cc(c1....
76 4N07 Kd = 0.35 uM 2J9 C10 H11 F N2 O2 S c1cc2c(cc1....
77 3IJO - GLU C5 H9 N O4 C(CC(=O)O)....
78 3RNN - RNN C16 H28 N2 O4 S2 CC(C)S(=O)....
79 2AL4 - QUS C5 H7 N3 O5 C([C@@H](C....
80 4LZ5 - GLU C5 H9 N O4 C(CC(=O)O)....
81 4U4S Kd = 1200 uM 3C1 C8 H11 N3 O2 S CCN1CNS(=O....
82 4G8M Kd = 12.8 nM G8M C7 H11 N O4 C1C[C@@H](....
83 3H6T - CYZ C14 H16 Cl N3 O4 S2 c1c2c(cc(c....
84 3O6G - O27 C23 H28 F3 N5 O2 S C1CCc2c(c(....
85 1NNP - CE2 C10 H15 N2 O4 CC(C)(C)c1....
86 5YBF Kd = 543 nM 8SR C16 H17 F3 N4 O2 S Cc1cc(nn1C....
87 1P1N Kd = 0.16 uM KAI C10 H15 N O4 CC(=C)[C@H....
88 1M5D ic50 = 9.2 uM BRH C6 H7 Br N2 O4 C(c1c(c(no....
89 3IK6 - GLU C5 H9 N O4 C(CC(=O)O)....
90 2XXI - JAC C18 H18 F3 N3 O2 c1cc(ccc1C....
91 4O3A Ki = 2.57 mM ASP C4 H7 N O4 C([C@@H](C....
92 3B6T - QUS C5 H7 N3 O5 C([C@@H](C....
93 4FAT - GLU C5 H9 N O4 C(CC(=O)O)....
94 3H6U - NS3 C18 H28 N4 O4 S2 Cc1cc2c(cc....
95 1NNK ic50 = 3.5 uM CE2 C10 H15 N2 O4 CC(C)(C)c1....
96 3FAT Ki = 22.8 nM AMQ C7 H10 N2 O4 Cc1c(c(no1....
97 3T9X - GLU C5 H9 N O4 C(CC(=O)O)....
98 1MY2 - AMQ C7 H10 N2 O4 Cc1c(c(no1....
99 3ILT - TRU C8 H8 Cl3 N3 O4 S2 c1c2c(cc(c....
100 3O6I - O26 C20 H29 N5 O2 S CC(C)(C)c1....
101 3DLN - GLU C5 H9 N O4 C(CC(=O)O)....
102 3RTW - NWD C7 H8 N4 O6 C1=C(C(=O)....
103 1MQD ic50 = 0.17 uM SHI C6 H8 N2 O4 c1c(c(no1)....
104 3T93 - GLU C5 H9 N O4 C(CC(=O)O)....
105 4F29 Ki = 0.168 uM QUS C5 H7 N3 O5 C([C@@H](C....
106 1MS7 ic50 = 0.17 uM SHI C6 H8 N2 O4 c1c(c(no1)....
107 3R7X ic50 = 0.082 uM QSN C12 H10 N6 O6 S CS(=O)(=O)....
108 3BFT Ki = 323 nM S2P C5 H7 N3 O3 S C(c1c(nsn1....
109 5JEI - FWD C7 H8 F N3 O4 C1=C(C(=O)....
110 3O28 - O28 C19 H21 F3 N4 O2 S C1CCc2c(c(....
111 4IY6 - MQS C15 H17 N3 O C[C@H]1CCC....
112 3LSL - PZI C6 H10 N2 O2 C1CC(=O)N(....
113 2XX7 - 1ND C19 H20 F3 N3 O c1cc(ccc1C....
114 1FTM Kd = 24.8 nM AMQ C7 H10 N2 O4 Cc1c(c(no1....
115 2GFE - GLU C5 H9 N O4 C(CC(=O)O)....
116 4F31 Ki = 2.08 uM KAI C10 H15 N O4 CC(=C)[C@H....
117 3T9U - CNI C9 H2 N4 O4 C1=C(C(=CC....
118 3T96 - IWD C7 H8 I N3 O4 C1=C(C(=O)....
119 3KFM - KAI C10 H15 N O4 CC(=C)[C@H....
120 2I3V - GLU C5 H9 N O4 C(CC(=O)O)....
121 3T9H - KAI C10 H15 N O4 CC(=C)[C@H....
122 3PMW - G69 C18 H22 F3 N3 O3 S CC(C)S(=O)....
123 3H6V - NS6 C18 H27 N3 O4 S2 CN1CCN(CC1....
124 1LBB - KAI C10 H15 N O4 CC(=C)[C@H....
125 5BUU - 4V6 C10 H13 Cl N2 O2 S C[C@@H]1N(....
126 3H03 ic50 = 135 uM UBP C10 H13 N3 O6 C1=CN(C(=O....
127 1LB9 - DNQ C8 H2 N4 O6 C1=C(C(=CC....
128 1N0T ic50 = 12.2 uM AT1 C11 H19 N2 O7 P CC(C)(C)c1....
129 3T9V - CNI C9 H2 N4 O4 C1=C(C(=CC....
130 1GR2 - KAI C10 H15 N O4 CC(=C)[C@H....
131 5OEW - GLU C5 H9 N O4 C(CC(=O)O)....
132 3IL1 - GLU C5 H9 N O4 C(CC(=O)O)....
133 3DP6 - GLU C5 H9 N O4 C(CC(=O)O)....
134 4O3C Ki = 2.57 mM ASP C4 H7 N O4 C([C@@H](C....
135 3RTF - CWD C7 H8 Cl N3 O4 C1=C(C(=O)....
136 6FAZ - GLU C5 H9 N O4 C(CC(=O)O)....
137 1MM6 ic50 = 20 nM QUS C5 H7 N3 O5 C([C@@H](C....
138 4F3G Ki = 3.44 uM KAI C10 H15 N O4 CC(=C)[C@H....
139 4IY5 - GLU C5 H9 N O4 C(CC(=O)O)....
140 4F39 Ki = 3.44 uM KAI C10 H15 N O4 CC(=C)[C@H....
141 5FHO - 5XN C14 H14 Cl N6 O4 c1cc(cc(c1....
142 2P2A Ki = 0.75 uM MP9 C14 H14 N6 O4 c1ccc(cc1)....
143 3TZA ic50 = 3.4 uM TZG C12 H13 Cl N2 O6 c1c(c(cc(c....
144 5NIH Ki = 237 nM 8VE C8 H11 N3 O4 CN1[C@H]2C....
145 3O2A - O30 C22 H28 F3 N5 O2 S C1CCc2c(c(....
146 4LZ8 - 1YX C19 H27 F N4 O4 S CC(C)S(=O)....
147 1MQJ ic50 = 4.76 uM HWD C7 H9 N3 O4 C1=CN(C(=O....
148 5NG9 Ki = 403 nM 8VN C7 H8 N2 O5 C1[C@H]2[C....
149 5NS9 - GLU C5 H9 N O4 C(CC(=O)O)....
150 4F1Y Kd = 0.96 uM CNI C9 H2 N4 O4 C1=C(C(=CC....
151 5ELV Kd = 0.16 uM 5PX C10 H12 N2 O3 S c1cc2c(cc1....
152 4U1O - KAI C10 H15 N O4 CC(=C)[C@H....
153 1LBC - GLU C5 H9 N O4 C(CC(=O)O)....
154 3TDJ - GLU C5 H9 N O4 C(CC(=O)O)....
155 5FHN - 5XO C15 H16 N6 O4 Cc1cccc(c1....
156 4QF9 Ki = 16.1 uM 35K C12 H13 N3 O4 c1cc2c(cc1....
157 1TXF Ki = 57.2 nM GLU C5 H9 N O4 C(CC(=O)O)....
158 3GBB Ki = 126 nM MS8 C11 H17 N O6 C1C[C@@H]2....
159 5MFQ - 2J9 C10 H11 F N2 O2 S c1cc2c(cc1....
160 3FVN Ki = 169 nM 9DX C11 H17 N O7 C1CO[C@@H]....
161 1YCJ - GLU C5 H9 N O4 C(CC(=O)O)....
162 3C35 - KAI C10 H15 N O4 CC(=C)[C@H....
163 5MFW - KAI C10 H15 N O4 CC(=C)[C@H....
164 3C31 - KAI C10 H15 N O4 CC(=C)[C@H....
165 3FV1 Ki = 0.5 nM DYH C12 H20 N2 O7 CN[C@@H]1[....
166 3C34 - KAI C10 H15 N O4 CC(=C)[C@H....
167 2F36 - GLU C5 H9 N O4 C(CC(=O)O)....
168 3GBA Ki = 0.848 nM DYH C12 H20 N2 O7 CN[C@@H]1[....
169 3FV2 Ki = 7.7 nM NDZ C11 H17 N O8 C1[C@@H]2[....
170 2QS4 Kd = 38 nM LY5 C16 H24 F2 N2 O4 C1C[C@H]2C....
171 2QS3 Kd = 1.4 nM UBE C20 H19 N3 O6 S CC1=CN(C(=....
172 2OJT - UBA C14 H15 N3 O6 S CC1=CN(C(=....
173 3C33 - KAI C10 H15 N O4 CC(=C)[C@H....
174 2WKY Ki = 2.57 nM IBC C11 H14 N2 O4 C1CC=C(c2c....
175 2PBW Ki = 5.56 nM DOQ C15 H21 N O6 C[C@H](C=C....
176 4YMB Ki = 0.62 uM 4E7 C15 H19 N O4 CCC[C@@H]1....
177 3FVG Ki = 128 nM MS8 C11 H17 N O6 C1C[C@@H]2....
178 3C36 - KAI C10 H15 N O4 CC(=C)[C@H....
179 2F34 Kd = 0.13 uM UBA C14 H15 N3 O6 S CC1=CN(C(=....
180 3C32 - KAI C10 H15 N O4 CC(=C)[C@H....
181 2QS2 Kd = 186 nM UBF C13 H12 Br N3 O6 S c1csc(c1CN....
182 4DLD Ki = 1.5 uM TZG C12 H13 Cl N2 O6 c1c(c(cc(c....
183 3FVK Ki = 1.5 nM 8DX C11 H17 N O7 C1[C@@H](C....
184 2ZNU Ki = 7.7 nM NDZ C11 H17 N O8 C1[C@@H]2[....
185 3S2V Ki = 157 nM 3HU C15 H13 N3 O6 S2 c1csc(c1CN....
186 2QS1 Kd = 33 nM UB1 C14 H13 Br2 N3 O6 S CC1=CN(C(=....
187 4E0X - KAI C10 H15 N O4 CC(=C)[C@H....
188 5MFV - KAI C10 H15 N O4 CC(=C)[C@H....
189 2ZNT Ki = 0.5 nM DYH C12 H20 N2 O7 CN[C@@H]1[....
190 2F35 Kd = 3.94 uM UBC C15 H15 N3 O6 c1ccc(c(c1....
191 5NEB Ki = 85 nM 8VE C8 H11 N3 O4 CN1[C@H]2C....
192 1VSO Ki = 18980 nM AT1 C11 H19 N2 O7 P CC(C)(C)c1....
193 4MH5 Ki = 7.43 uM GGL C5 H9 N O4 C(CC(=O)O)....
194 3U92 - KAI C10 H15 N O4 CC(=C)[C@H....
195 4E0W - KAI C10 H15 N O4 CC(=C)[C@H....
196 5O4F Ki = 22 nM 8VE C8 H11 N3 O4 CN1[C@H]2C....
197 4NWC Ki = 1.74 uM 2QE C9 H15 N O6 COC(=O)CC[....
198 4G8N Kd = 63 nM G8M C7 H11 N O4 C1C[C@@H](....
199 6F28 Ki = 2.15 uM CG8 C10 H14 N4 O4 CN1CC2=C(C....
200 5EHM - OEM C5 H9 N O4 CN[C@H](CC....
201 5EHS - 2JJ C5 H12 N O5 P C(C[C@H](C....
202 5DTB - GLU C5 H9 N O4 C(CC(=O)O)....
203 4F2O Ki = 0.042 uM QUS C5 H7 N3 O5 C([C@@H](C....
204 3DP4 Kd = 43 nM AMQ C7 H10 N2 O4 Cc1c(c(no1....
205 4F22 Ki = 30.26 uM KAI C10 H15 N O4 CC(=C)[C@H....
206 4F3B Ki = 1.271 uM GLU C5 H9 N O4 C(CC(=O)O)....
207 4F2Q Ki = 0.042 uM QUS C5 H7 N3 O5 C([C@@H](C....
208 3RT8 - CWD C7 H8 Cl N3 O4 C1=C(C(=O)....
209 3M3F - P99 C16 H16 F2 N2 O4 S2 c1ccc(cc1)....
210 3LSX - PZI C6 H10 N2 O2 C1CC(=O)N(....
211 3LSW - GLU C5 H9 N O4 C(CC(=O)O)....
212 4H8I - 11W C20 H21 N3 O4 c1ccc(cc1)....
213 4BDQ - CYS C3 H7 N O2 S C([C@@H](C....
214 2XXW - GLU C5 H9 N O4 C(CC(=O)O)....
215 1SD3 - SYM C6 H10 N O4 C[C@H](C[C....
216 2XXX - GLU C5 H9 N O4 C(CC(=O)O)....
217 2XXR - GLU C5 H9 N O4 C(CC(=O)O)....
218 3QXM Ki = 33 nM NDZ C11 H17 N O8 C1[C@@H]2[....
219 1S9T Ki = 253 nM QUS C5 H7 N3 O5 C([C@@H](C....
220 4BDR - KAI C10 H15 N O4 CC(=C)[C@H....
221 2XXT - KAI C10 H15 N O4 CC(=C)[C@H....
222 5CMM - SYM C6 H10 N O4 C[C@H](C[C....
223 2XXU - GLU C5 H9 N O4 C(CC(=O)O)....
224 4BDN - GLU C5 H9 N O4 C(CC(=O)O)....
225 1S50 Ki = 1.4 uM GLU C5 H9 N O4 C(CC(=O)O)....
226 2XXV - KAI C10 H15 N O4 CC(=C)[C@H....
227 5CMK ic50 = 30 nM LY5 C16 H24 F2 N2 O4 C1C[C@H]2C....
228 4BDL - GLU C5 H9 N O4 C(CC(=O)O)....
229 1S7Y Ki = 1.4 uM GLU C5 H9 N O4 C(CC(=O)O)....
230 1TT1 Ki = 64.6 nM KAI C10 H15 N O4 CC(=C)[C@H....
231 5IKB Kd = 1.9 nM KAI C10 H15 N O4 CC(=C)[C@H....
232 5DT6 - GLU C5 H9 N O4 C(CC(=O)O)....
233 5ICT - GLU C5 H9 N O4 C(CC(=O)O)....
50% Homology Family (240)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 174 families.
1 4O3B Ki = 0.82 uM GLU C5 H9 N O4 C(CC(=O)O)....
2 5CBS Kd = 3.9 uM E42 C15 H15 N O3 c1cc(cc(c1....
3 3PD8 Ki = 108 nM HA7 C7 H8 N2 O4 C1CN[C@@H]....
4 1P1O Kd = 1.74 uM QUS C5 H7 N3 O5 C([C@@H](C....
5 1MQH ic50 = 0.3 uM BWD C7 H8 Br N3 O4 C1=C(C(=O)....
6 1FTK ic50 = 14.5 uM KAI C10 H15 N O4 CC(=C)[C@H....
7 3TKD - CYZ C14 H16 Cl N3 O4 S2 c1c2c(cc(c....
8 1M5F ic50 = 14.8 nM AM1 C8 H10 N2 O5 Cc1c(c(no1....
9 5FTI - GLU C5 H9 N O4 C(CC(=O)O)....
10 1XHY Ki = 624 nM KAI C10 H15 N O4 CC(=C)[C@H....
11 1M5C ic50 = 0.5 uM BRH C6 H7 Br N2 O4 C(c1c(c(no....
12 1SYI Ki = 3330 nM CPW C10 H13 N3 O4 C1CC2=C(C1....
13 5O9A - 7M6 C9 H10 Cl F N2 O2 S c1cc2c(cc1....
14 1MY3 - BWD C7 H8 Br N3 O4 C1=C(C(=O)....
15 3ILU - HFZ C8 H8 F3 N3 O4 S2 c1c(c(cc2c....
16 3PMV - 557 C17 H22 F3 N3 O3 S C[C@H](CNS....
17 5H8S - 5YC C15 H16 N4 O S CCN(CC1=CC....
18 2XHD - GLU C5 H9 N O4 C(CC(=O)O)....
19 3B7D - CNI C9 H2 N4 O4 C1=C(C(=CC....
20 4U1Z - KAI C10 H15 N O4 CC(=C)[C@H....
21 1WVJ Ki = 185 nM IBC C11 H14 N2 O4 C1CC=C(c2c....
22 1P1U - AMQ C7 H10 N2 O4 Cc1c(c(no1....
23 4Q30 - NWD C7 H8 N4 O6 C1=C(C(=O)....
24 4U23 - FWD C7 H8 F N3 O4 C1=C(C(=O)....
25 1MQG ic50 = 0.52 uM IWD C7 H8 I N3 O4 C1=C(C(=O)....
26 3BBR - BHY C20 H28 N2 O4 S2 C[C@@H](CN....
27 3LSF - PZI C6 H10 N2 O2 C1CC(=O)N(....
28 3PMX - 808 C18 H20 F3 N O3 S CC(C)S(=O)....
29 2ANJ - KAI C10 H15 N O4 CC(=C)[C@H....
30 2XX8 - 1NE C17 H18 F3 N3 O CN(C)C(=O)....
31 1P1Q Kd = 12.8 uM AMQ C7 H10 N2 O4 Cc1c(c(no1....
32 2AL5 - FWD C7 H8 F N3 O4 C1=C(C(=O)....
33 5YBG ic50 = 0.03 uM 8SO C21 H30 N2 O4 S2 C[C@@H](CN....
34 1M5E ic50 = 20.1 nM AM1 C8 H10 N2 O5 Cc1c(c(no1....
35 3BKI ic50 = 7.6 uM FQX C8 H4 N4 O4 c1c2c(cc3c....
36 2AIX - U1K C10 H16 N2 O3 S CC(C)(C)c1....
37 3B6W - GLU C5 H9 N O4 C(CC(=O)O)....
38 2I3W - GLU C5 H9 N O4 C(CC(=O)O)....
39 3O6H - O25 C18 H22 F3 N5 O2 S CCNCc1cn(n....
40 3KGC - ZK1 C14 H15 F3 N3 O6 P c1c(c(cc2c....
41 3BFU Ki = 531 nM R2P C5 H7 N3 O3 S C(c1c(nsn1....
42 3UA8 ic50 = 14 nM 08W C15 H13 F3 N6 O5 S CNC(=O)c1c....
43 4LZ7 - GLU C5 H9 N O4 C(CC(=O)O)....
44 1FTL ic50 = 998 nM DNQ C8 H2 N4 O6 C1=C(C(=CC....
45 3B6Q - GLU C5 H9 N O4 C(CC(=O)O)....
46 3RN8 - RN8 C22 H16 N2 O4 S2 CCc1c(c(c(....
47 1P1W - AMQ C7 H10 N2 O4 Cc1c(c(no1....
48 1MQI ic50 = 23.53 nM FWD C7 H8 F N3 O4 C1=C(C(=O)....
49 3O29 - O29 C23 H30 F3 N5 O2 S CN(C)CCNC(....
50 1FTJ ic50 = 821 nM GLU C5 H9 N O4 C(CC(=O)O)....
51 3PD9 Ki = 494 nM HA5 C7 H8 N2 O4 C1c2c(onc2....
52 1M5B ic50 = 9.7 nM BN1 C8 H10 N6 O4 Cn1nc(nn1)....
53 3EN3 - KAI C10 H15 N O4 CC(=C)[C@H....
54 1SYH Ki = 393 nM CPW C10 H13 N3 O4 C1CC2=C(C1....
55 4X48 - XPF C18 H20 N2 O4 S2 CC(C)S(=O)....
56 3H6W - NS7 C19 H29 N3 O4 S2 Cc1cc2c(cc....
57 1MY4 - IWD C7 H8 I N3 O4 C1=C(C(=O)....
58 4IGT Ki = 40.8 uM 3ZA C9 H16 N2 O6 CN(C(=O)CC....
59 3M3L - P99 C16 H16 F2 N2 O4 S2 c1ccc(cc1)....
60 5CBR Kd = 1.8 uM 4ZK C14 H12 Cl2 N2 O3 c1c(cc(c(c....
61 4GXS - 0YS C18 H21 Cl2 N3 O9 c1c(cc(c(c....
62 4U21 - FWF C24 H36 N2 O4 S2 C[C@@H](CN....
63 4YMA - 4E5 C12 H13 N O5 c1c(cc(cc1....
64 1FW0 - KAI C10 H15 N O4 CC(=C)[C@H....
65 1LB8 - AMQ C7 H10 N2 O4 Cc1c(c(no1....
66 3FAS Ki = 171 nM GLU C5 H9 N O4 C(CC(=O)O)....
67 4U22 - FWD C7 H8 F N3 O4 C1=C(C(=O)....
68 4ISU Ki = 0.21 mM IKM C12 H14 N2 O6 C1C=C[C@H]....
69 1MXU ic50 = 4 uM BWD C7 H8 Br N3 O4 C1=C(C(=O)....
70 4U4X Kd = 9.8 uM 3C2 C8 H11 N3 O2 S CCN1CNS(=O....
71 1MM7 ic50 = 20 nM QUS C5 H7 N3 O5 C([C@@H](C....
72 2XX9 - 1NF C19 H19 F4 N3 O c1cc(c(cc1....
73 3M3K - GLU C5 H9 N O4 C(CC(=O)O)....
74 2XXH - 1NG C20 H22 F3 N3 O c1cc(ccc1C....
75 5FHM - 5XP C15 H17 N7 O4 c1cc(cc(c1....
76 4N07 Kd = 0.35 uM 2J9 C10 H11 F N2 O2 S c1cc2c(cc1....
77 3IJO - GLU C5 H9 N O4 C(CC(=O)O)....
78 3RNN - RNN C16 H28 N2 O4 S2 CC(C)S(=O)....
79 2AL4 - QUS C5 H7 N3 O5 C([C@@H](C....
80 4LZ5 - GLU C5 H9 N O4 C(CC(=O)O)....
81 4U4S Kd = 1200 uM 3C1 C8 H11 N3 O2 S CCN1CNS(=O....
82 4G8M Kd = 12.8 nM G8M C7 H11 N O4 C1C[C@@H](....
83 3H6T - CYZ C14 H16 Cl N3 O4 S2 c1c2c(cc(c....
84 3O6G - O27 C23 H28 F3 N5 O2 S C1CCc2c(c(....
85 1NNP - CE2 C10 H15 N2 O4 CC(C)(C)c1....
86 5YBF Kd = 543 nM 8SR C16 H17 F3 N4 O2 S Cc1cc(nn1C....
87 1P1N Kd = 0.16 uM KAI C10 H15 N O4 CC(=C)[C@H....
88 1M5D ic50 = 9.2 uM BRH C6 H7 Br N2 O4 C(c1c(c(no....
89 3IK6 - GLU C5 H9 N O4 C(CC(=O)O)....
90 2XXI - JAC C18 H18 F3 N3 O2 c1cc(ccc1C....
91 4O3A Ki = 2.57 mM ASP C4 H7 N O4 C([C@@H](C....
92 3B6T - QUS C5 H7 N3 O5 C([C@@H](C....
93 4FAT - GLU C5 H9 N O4 C(CC(=O)O)....
94 3H6U - NS3 C18 H28 N4 O4 S2 Cc1cc2c(cc....
95 1NNK ic50 = 3.5 uM CE2 C10 H15 N2 O4 CC(C)(C)c1....
96 3FAT Ki = 22.8 nM AMQ C7 H10 N2 O4 Cc1c(c(no1....
97 3T9X - GLU C5 H9 N O4 C(CC(=O)O)....
98 1MY2 - AMQ C7 H10 N2 O4 Cc1c(c(no1....
99 3ILT - TRU C8 H8 Cl3 N3 O4 S2 c1c2c(cc(c....
100 3O6I - O26 C20 H29 N5 O2 S CC(C)(C)c1....
101 3DLN - GLU C5 H9 N O4 C(CC(=O)O)....
102 3RTW - NWD C7 H8 N4 O6 C1=C(C(=O)....
103 1MQD ic50 = 0.17 uM SHI C6 H8 N2 O4 c1c(c(no1)....
104 3T93 - GLU C5 H9 N O4 C(CC(=O)O)....
105 4F29 Ki = 0.168 uM QUS C5 H7 N3 O5 C([C@@H](C....
106 1MS7 ic50 = 0.17 uM SHI C6 H8 N2 O4 c1c(c(no1)....
107 3R7X ic50 = 0.082 uM QSN C12 H10 N6 O6 S CS(=O)(=O)....
108 3BFT Ki = 323 nM S2P C5 H7 N3 O3 S C(c1c(nsn1....
109 5JEI - FWD C7 H8 F N3 O4 C1=C(C(=O)....
110 3O28 - O28 C19 H21 F3 N4 O2 S C1CCc2c(c(....
111 4IY6 - MQS C15 H17 N3 O C[C@H]1CCC....
112 3LSL - PZI C6 H10 N2 O2 C1CC(=O)N(....
113 2XX7 - 1ND C19 H20 F3 N3 O c1cc(ccc1C....
114 1FTM Kd = 24.8 nM AMQ C7 H10 N2 O4 Cc1c(c(no1....
115 2GFE - GLU C5 H9 N O4 C(CC(=O)O)....
116 4F31 Ki = 2.08 uM KAI C10 H15 N O4 CC(=C)[C@H....
117 3T9U - CNI C9 H2 N4 O4 C1=C(C(=CC....
118 3T96 - IWD C7 H8 I N3 O4 C1=C(C(=O)....
119 3KFM - KAI C10 H15 N O4 CC(=C)[C@H....
120 2I3V - GLU C5 H9 N O4 C(CC(=O)O)....
121 3T9H - KAI C10 H15 N O4 CC(=C)[C@H....
122 3PMW - G69 C18 H22 F3 N3 O3 S CC(C)S(=O)....
123 3H6V - NS6 C18 H27 N3 O4 S2 CN1CCN(CC1....
124 1LBB - KAI C10 H15 N O4 CC(=C)[C@H....
125 5BUU - 4V6 C10 H13 Cl N2 O2 S C[C@@H]1N(....
126 3H03 ic50 = 135 uM UBP C10 H13 N3 O6 C1=CN(C(=O....
127 1LB9 - DNQ C8 H2 N4 O6 C1=C(C(=CC....
128 1N0T ic50 = 12.2 uM AT1 C11 H19 N2 O7 P CC(C)(C)c1....
129 3T9V - CNI C9 H2 N4 O4 C1=C(C(=CC....
130 1GR2 - KAI C10 H15 N O4 CC(=C)[C@H....
131 5OEW - GLU C5 H9 N O4 C(CC(=O)O)....
132 3IL1 - GLU C5 H9 N O4 C(CC(=O)O)....
133 3DP6 - GLU C5 H9 N O4 C(CC(=O)O)....
134 4O3C Ki = 2.57 mM ASP C4 H7 N O4 C([C@@H](C....
135 3RTF - CWD C7 H8 Cl N3 O4 C1=C(C(=O)....
136 6FAZ - GLU C5 H9 N O4 C(CC(=O)O)....
137 1MM6 ic50 = 20 nM QUS C5 H7 N3 O5 C([C@@H](C....
138 4F3G Ki = 3.44 uM KAI C10 H15 N O4 CC(=C)[C@H....
139 4IY5 - GLU C5 H9 N O4 C(CC(=O)O)....
140 4F39 Ki = 3.44 uM KAI C10 H15 N O4 CC(=C)[C@H....
141 5FHO - 5XN C14 H14 Cl N6 O4 c1cc(cc(c1....
142 2P2A Ki = 0.75 uM MP9 C14 H14 N6 O4 c1ccc(cc1)....
143 3TZA ic50 = 3.4 uM TZG C12 H13 Cl N2 O6 c1c(c(cc(c....
144 5NIH Ki = 237 nM 8VE C8 H11 N3 O4 CN1[C@H]2C....
145 3O2A - O30 C22 H28 F3 N5 O2 S C1CCc2c(c(....
146 4LZ8 - 1YX C19 H27 F N4 O4 S CC(C)S(=O)....
147 1MQJ ic50 = 4.76 uM HWD C7 H9 N3 O4 C1=CN(C(=O....
148 5NG9 Ki = 403 nM 8VN C7 H8 N2 O5 C1[C@H]2[C....
149 5NS9 - GLU C5 H9 N O4 C(CC(=O)O)....
150 4F1Y Kd = 0.96 uM CNI C9 H2 N4 O4 C1=C(C(=CC....
151 5ELV Kd = 0.16 uM 5PX C10 H12 N2 O3 S c1cc2c(cc1....
152 4U1O - KAI C10 H15 N O4 CC(=C)[C@H....
153 1LBC - GLU C5 H9 N O4 C(CC(=O)O)....
154 3TDJ - GLU C5 H9 N O4 C(CC(=O)O)....
155 5FHN - 5XO C15 H16 N6 O4 Cc1cccc(c1....
156 4QF9 Ki = 16.1 uM 35K C12 H13 N3 O4 c1cc2c(cc1....
157 1TXF Ki = 57.2 nM GLU C5 H9 N O4 C(CC(=O)O)....
158 3GBB Ki = 126 nM MS8 C11 H17 N O6 C1C[C@@H]2....
159 5MFQ - 2J9 C10 H11 F N2 O2 S c1cc2c(cc1....
160 3FVN Ki = 169 nM 9DX C11 H17 N O7 C1CO[C@@H]....
161 1YCJ - GLU C5 H9 N O4 C(CC(=O)O)....
162 3C35 - KAI C10 H15 N O4 CC(=C)[C@H....
163 5MFW - KAI C10 H15 N O4 CC(=C)[C@H....
164 3C31 - KAI C10 H15 N O4 CC(=C)[C@H....
165 3FV1 Ki = 0.5 nM DYH C12 H20 N2 O7 CN[C@@H]1[....
166 3C34 - KAI C10 H15 N O4 CC(=C)[C@H....
167 2F36 - GLU C5 H9 N O4 C(CC(=O)O)....
168 3GBA Ki = 0.848 nM DYH C12 H20 N2 O7 CN[C@@H]1[....
169 3FV2 Ki = 7.7 nM NDZ C11 H17 N O8 C1[C@@H]2[....
170 2QS4 Kd = 38 nM LY5 C16 H24 F2 N2 O4 C1C[C@H]2C....
171 2QS3 Kd = 1.4 nM UBE C20 H19 N3 O6 S CC1=CN(C(=....
172 2OJT - UBA C14 H15 N3 O6 S CC1=CN(C(=....
173 3C33 - KAI C10 H15 N O4 CC(=C)[C@H....
174 2WKY Ki = 2.57 nM IBC C11 H14 N2 O4 C1CC=C(c2c....
175 2PBW Ki = 5.56 nM DOQ C15 H21 N O6 C[C@H](C=C....
176 4YMB Ki = 0.62 uM 4E7 C15 H19 N O4 CCC[C@@H]1....
177 3FVG Ki = 128 nM MS8 C11 H17 N O6 C1C[C@@H]2....
178 3C36 - KAI C10 H15 N O4 CC(=C)[C@H....
179 2F34 Kd = 0.13 uM UBA C14 H15 N3 O6 S CC1=CN(C(=....
180 3C32 - KAI C10 H15 N O4 CC(=C)[C@H....
181 2QS2 Kd = 186 nM UBF C13 H12 Br N3 O6 S c1csc(c1CN....
182 4DLD Ki = 1.5 uM TZG C12 H13 Cl N2 O6 c1c(c(cc(c....
183 3FVK Ki = 1.5 nM 8DX C11 H17 N O7 C1[C@@H](C....
184 2ZNU Ki = 7.7 nM NDZ C11 H17 N O8 C1[C@@H]2[....
185 3S2V Ki = 157 nM 3HU C15 H13 N3 O6 S2 c1csc(c1CN....
186 2QS1 Kd = 33 nM UB1 C14 H13 Br2 N3 O6 S CC1=CN(C(=....
187 4E0X - KAI C10 H15 N O4 CC(=C)[C@H....
188 5MFV - KAI C10 H15 N O4 CC(=C)[C@H....
189 2ZNT Ki = 0.5 nM DYH C12 H20 N2 O7 CN[C@@H]1[....
190 2F35 Kd = 3.94 uM UBC C15 H15 N3 O6 c1ccc(c(c1....
191 5NEB Ki = 85 nM 8VE C8 H11 N3 O4 CN1[C@H]2C....
192 1VSO Ki = 18980 nM AT1 C11 H19 N2 O7 P CC(C)(C)c1....
193 5CC2 Kd = 80 uM CKA C10 H6 Cl N O3 c1cc2c(cc1....
194 2V3U Kd = 1 mM DSN C3 H7 N O3 C([C@H](C(....
195 4MH5 Ki = 7.43 uM GGL C5 H9 N O4 C(CC(=O)O)....
196 3U92 - KAI C10 H15 N O4 CC(=C)[C@H....
197 4E0W - KAI C10 H15 N O4 CC(=C)[C@H....
198 5O4F Ki = 22 nM 8VE C8 H11 N3 O4 CN1[C@H]2C....
199 4NWC Ki = 1.74 uM 2QE C9 H15 N O6 COC(=O)CC[....
200 4G8N Kd = 63 nM G8M C7 H11 N O4 C1C[C@@H](....
201 6F28 Ki = 2.15 uM CG8 C10 H14 N4 O4 CN1CC2=C(C....
202 5CMB Kd = 28.3 nM GLY C2 H5 N O2 C(C(=O)O)N
203 4YKJ Ki = 37 uM ALA C3 H7 N O2 C[C@@H](C(....
204 4YKI Kd = 2.7 nM GLY C2 H5 N O2 C(C(=O)O)N
205 4YKP - GLY C2 H5 N O2 C(C(=O)O)N
206 5EHM - OEM C5 H9 N O4 CN[C@H](CC....
207 5EHS - 2JJ C5 H12 N O5 P C(C[C@H](C....
208 5DTB - GLU C5 H9 N O4 C(CC(=O)O)....
209 4F2O Ki = 0.042 uM QUS C5 H7 N3 O5 C([C@@H](C....
210 3DP4 Kd = 43 nM AMQ C7 H10 N2 O4 Cc1c(c(no1....
211 4F22 Ki = 30.26 uM KAI C10 H15 N O4 CC(=C)[C@H....
212 4F3B Ki = 1.271 uM GLU C5 H9 N O4 C(CC(=O)O)....
213 4F2Q Ki = 0.042 uM QUS C5 H7 N3 O5 C([C@@H](C....
214 3RT8 - CWD C7 H8 Cl N3 O4 C1=C(C(=O)....
215 3M3F - P99 C16 H16 F2 N2 O4 S2 c1ccc(cc1)....
216 3LSX - PZI C6 H10 N2 O2 C1CC(=O)N(....
217 3LSW - GLU C5 H9 N O4 C(CC(=O)O)....
218 4WXJ - GLU C5 H9 N O4 C(CC(=O)O)....
219 4H8I - 11W C20 H21 N3 O4 c1ccc(cc1)....
220 4BDQ - CYS C3 H7 N O2 S C([C@@H](C....
221 2XXW - GLU C5 H9 N O4 C(CC(=O)O)....
222 1SD3 - SYM C6 H10 N O4 C[C@H](C[C....
223 2XXX - GLU C5 H9 N O4 C(CC(=O)O)....
224 2XXR - GLU C5 H9 N O4 C(CC(=O)O)....
225 3QXM Ki = 33 nM NDZ C11 H17 N O8 C1[C@@H]2[....
226 1S9T Ki = 253 nM QUS C5 H7 N3 O5 C([C@@H](C....
227 4BDR - KAI C10 H15 N O4 CC(=C)[C@H....
228 2XXT - KAI C10 H15 N O4 CC(=C)[C@H....
229 5CMM - SYM C6 H10 N O4 C[C@H](C[C....
230 2XXU - GLU C5 H9 N O4 C(CC(=O)O)....
231 4BDN - GLU C5 H9 N O4 C(CC(=O)O)....
232 1S50 Ki = 1.4 uM GLU C5 H9 N O4 C(CC(=O)O)....
233 2XXV - KAI C10 H15 N O4 CC(=C)[C@H....
234 5CMK ic50 = 30 nM LY5 C16 H24 F2 N2 O4 C1C[C@H]2C....
235 4BDL - GLU C5 H9 N O4 C(CC(=O)O)....
236 1S7Y Ki = 1.4 uM GLU C5 H9 N O4 C(CC(=O)O)....
237 1TT1 Ki = 64.6 nM KAI C10 H15 N O4 CC(=C)[C@H....
238 5IKB Kd = 1.9 nM KAI C10 H15 N O4 CC(=C)[C@H....
239 5DT6 - GLU C5 H9 N O4 C(CC(=O)O)....
240 5ICT - GLU C5 H9 N O4 C(CC(=O)O)....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: QUS; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 QUS 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4F2Q; Ligand: QUS; Similar sites found with APoc: 167
This union binding pocket(no: 1) in the query (biounit: 4f2q.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 1LK7 DER 0.873362
2 5O4J 9KH 1.16279
3 5O4J PJL 1.16279
4 5O4J SAH 1.16279
5 5A96 GTP 1.20482
6 1Q0H NDP 1.55039
7 1YQT ADP 1.55039
8 2PZE ATP 1.74672
9 5I60 67W 1.93798
10 1CT9 GLN 1.93798
11 5TS5 FAD 1.93798
12 3CRZ FAD 1.94553
13 3W5J GDP 1.96078
14 1C3V PDC 2.04082
15 2AWN ADP 2.32558
16 3ITJ CIT 2.32558
17 3WQQ NDP 2.32558
18 3WQQ IB3 2.32558
19 3ITJ FAD 2.32558
20 1REO FAD 2.32558
21 1EJB INJ 2.38095
22 4LAE NAP 2.39521
23 4LAE 1VM 2.39521
24 5ZBC FAD 2.71318
25 2POC BG6 2.71318
26 1H82 FAD 2.71318
27 1H82 GZZ 2.71318
28 2B8W ALF 5GP 2.71318
29 5HSA FAS 2.71318
30 2GMH FAD 2.71318
31 1JJ7 ADP 2.71318
32 4CLO XP0 2.71318
33 1RRC ADP 3.10078
34 5UR1 YY9 3.10078
35 3E1T FAD 3.10078
36 4AG5 ADP 3.10078
37 4OOE FOM 3.10078
38 4OOE NDP 3.10078
39 3A4M ADP 3.10078
40 5YV5 ADP 3.10078
41 5Z2F PDC 3.10078
42 1M0S CIT 3.19635
43 1YKJ FAD 3.48837
44 1YKJ PHB 3.48837
45 5OCQ CIT 3.48837
46 5MBX SP5 3.48837
47 5MBX FAD 3.48837
48 3OND ADN 3.48837
49 3OND NAD 3.48837
50 5UAO FAD 3.48837
51 1A8R GTP 3.61991
52 2B6N ALA PRO THR 3.87597
53 2ZJ3 G6P 3.87597
54 1Q19 SSC 3.87597
55 2JB2 PHE 3.87597
56 2JB2 FAD 3.87597
57 3X0V FAD 3.87597
58 1M2O GNP 3.87597
59 2VVM FAD 3.87597
60 5W8Q BU4 3.87597
61 2VVL FAD 3.87597
62 6F3M NAD 3.87597
63 4MUV PCG 4.22535
64 5NM7 GLY 4.26357
65 1KJ8 GAR 4.26357
66 5CGE 51F 4.26357
67 4NVP 7CH 4.30622
68 3N26 ARG 4.47154
69 3JUC PCA 4.57516
70 2WET FAD 4.65116
71 5BUK FAD 4.65116
72 5M67 NAD 4.65116
73 5M67 3D1 4.65116
74 4BVA NDP 5.03876
75 4JX1 CAH 5.03876
76 5OSW DIU 5.03876
77 5TSH ADP 5.42636
78 1U6R IOM 5.42636
79 5YU3 PRO 5.42636
80 5YU3 NAD 5.42636
81 2VOH CIT 5.73248
82 5JCM ISD 5.81395
83 3UWV 2PG 5.81395
84 2YG3 FAD 5.81395
85 3UYK 0CX 5.81395
86 1RSG FAD 5.81395
87 1NE7 AGP 5.81395
88 1WUR 8DG 5.90909
89 2W58 ADP 5.94059
90 3B8I OXL 6.20155
91 1YY5 FAD 6.20155
92 2F5X ASP 6.20155
93 3KDM TES 6.22222
94 1S7G APR 6.32411
95 1NVM NAD 6.37681
96 4GUS FAD 6.45161
97 4HSU FAD 6.45161
98 4GUT FAD 6.45161
99 3KV8 FAH 6.47482
100 5E5U MLI 6.58915
101 3QJ4 FAD 6.58915
102 5BVA FAD 6.58915
103 3GGO NAI 6.58915
104 3GGO ENO 6.58915
105 3QFA FAD 6.89655
106 5C8W PCG 6.99301
107 4KQ6 DLZ 7.26257
108 1XX6 ADP 7.32984
109 3NOJ PYR 7.36434
110 2Z3Y F2N 7.36434
111 4WMY 3S6 7.36434
112 6FHO FAD 7.36434
113 1D8C GLV 7.36434
114 1G6H ADP 7.393
115 1NXJ TLA 7.65027
116 2DVZ GLU 7.75194
117 4AMV F6R 7.75194
118 1MOQ GLP 7.75194
119 1LVG ADP 8.08081
120 4PPF FLC 8.13953
121 3G4Q MCH 8.21918
122 5TVM PUT 8.23529
123 1EE0 CAA 8.52713
124 4LY9 1YY 8.91473
125 4LY9 S6P 8.91473
126 6HKE MLT 8.91473
127 6HKE LMR 8.91473
128 3ZEI AWH 8.91473
129 3EKK GS2 9.30233
130 3DRG ARG PRO PRO GLY PHE SER PRO PHE ALA 9.30233
131 1KYV RBF 9.43396
132 5AA4 6X4 10.0775
133 2QTV GNP 10.1796
134 1XT8 CYS 10.8527
135 4LZJ 22H 10.8527
136 4DSG FAD 10.8527
137 3WH2 FLC 10.8844
138 1GXU 2HP 10.989
139 5G3U ITW 11.6279
140 5G3U FDA 11.6279
141 3IA4 NDP 11.7284
142 2AMT GPP 11.9497
143 4U00 ADP 12.2951
144 2EIX FAD 13.5802
145 5WX3 COA 14.7287
146 1R4A GNP 15.6863
147 5ORG 6DB 15.8915
148 5FJJ MAN 16.2791
149 2YLN CYS 18.9922
150 2Q89 6CS 20.2335
151 6H1U ASP 20.9302
152 4KQP GLN 21.1207
153 1LAF ARG 22.6891
154 2YJP CYS 22.8682
155 2VHA GLU 28.2946
156 1II5 GLU 30.0429
157 4C0R GDS 35.8871
158 6GPC ARG 36.5079
159 3VV5 SLZ 39.5349
160 4POW OP1 39.9225
161 1HSL HIS 40.7563
162 5L9O GOP 41.0853
163 4YMX ARG 41.4729
164 4DZ1 DAL 42.2481
165 2Y7I ARG 43.2314
166 4ZV1 ARG 45.0644
167 1WDN GLN 47.3451
Pocket No.: 2; Query (leader) PDB : 4F2Q; Ligand: QUS; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4f2q.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
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