Receptor
PDB id Resolution Class Description Source Keywords
4G0A 2.1 Å EC: 3.6.4.- CRYSTALLOGRAPHIC ANALYSIS OF ROTAVIRUS NSP2-RNA COMPLEX REVE SPECIFIC RECOGNITION OF 5'-GG SEQUENCE FOR RTPASE ACTIVITY SIMIAN 11 ROTAVIRUS RNA TRIPHOSPHATASE RNA BINDING HYDROLASE ACTIVITY NUCLEOTBINDING METAL ION BINDING HOST CELL CYTOPLASM HYDROLASE-COMPLEX
Ref.: CRYSTALLOGRAPHIC ANALYSIS OF ROTAVIRUS NSP2-RNA COM REVEALS SPECIFIC RECOGNITION OF 5' GG SEQUENCE FOR ACTIVITY. J.VIROL. V. 86 10547 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CL A:1201;
B:1200;
C:401;
D:401;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
35.453 Cl [Cl-]
G G U E:1;
F:1;
G:1;
H:1;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
754.396 n/a [P+](...
NA C:402;
Invalid;
none;
submit data
22.99 Na [Na+]
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4G0A 2.1 Å EC: 3.6.4.- CRYSTALLOGRAPHIC ANALYSIS OF ROTAVIRUS NSP2-RNA COMPLEX REVE SPECIFIC RECOGNITION OF 5'-GG SEQUENCE FOR RTPASE ACTIVITY SIMIAN 11 ROTAVIRUS RNA TRIPHOSPHATASE RNA BINDING HYDROLASE ACTIVITY NUCLEOTBINDING METAL ION BINDING HOST CELL CYTOPLASM HYDROLASE-COMPLEX
Ref.: CRYSTALLOGRAPHIC ANALYSIS OF ROTAVIRUS NSP2-RNA COM REVEALS SPECIFIC RECOGNITION OF 5' GG SEQUENCE FOR ACTIVITY. J.VIROL. V. 86 10547 2012
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 4G0A - G G U n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 4G0A - G G U n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 4G0A - G G U n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: G G U; Similar ligands found: 90
No: Ligand ECFP6 Tc MDL keys Tc
1 G G U 1 1
2 G G G C 0.692308 0.949367
3 G G 0.682692 0.973684
4 G C C C 0.663934 0.936709
5 G A A A 0.608333 0.961039
6 U A G G 0.590164 0.973684
7 G G G RPC 0.586777 0.935897
8 G3D 0.584906 0.947368
9 A G C C 0.579365 0.924051
10 G4P 0.574074 0.947368
11 G C 0.57377 0.9125
12 APC G U 0.568 0.948052
13 3GP 0.56 0.934211
14 0O2 0.553571 0.947368
15 GDP MG 0.542056 0.911392
16 ALF 5GP 0.537037 0.878049
17 GDP BEF 0.537037 0.888889
18 A G U 0.52518 0.925
19 BEF GDP 0.522523 0.878049
20 GTP MG 0.522523 0.911392
21 U G A 0.521429 0.925
22 5GP 0.519231 0.947368
23 G 0.519231 0.947368
24 GDP 0.509259 0.935065
25 GDP ALF 0.508772 0.878049
26 GDP AF3 0.508772 0.878049
27 GNH 0.504587 0.923077
28 GP3 0.5 0.961039
29 GSP 0.5 0.888889
30 GP2 0.495413 0.9
31 A A 0.491379 0.907895
32 GCP G 0.491228 0.923077
33 G1R 0.491071 0.923077
34 GCP 0.491071 0.911392
35 GMP 0.484848 0.820513
36 GDP 7MG 0.483607 0.948718
37 GMV 0.482143 0.911392
38 GTP 0.482143 0.935065
39 GPG 0.474576 0.948718
40 GNP 0.473684 0.911392
41 G2P 0.473684 0.9
42 2GP 0.471698 0.922078
43 DG DC 0.467153 0.890244
44 G2R 0.466102 0.9
45 GAV 0.465517 0.9
46 DG DG 0.462185 0.925
47 GDD 0.459016 0.924051
48 GKE 0.459016 0.924051
49 GDC 0.459016 0.924051
50 BGO 0.453846 0.936709
51 6CK 0.451613 0.901235
52 U A A U 0.45 0.898734
53 Y9Z 0.447154 0.847059
54 GKD 0.444444 0.924051
55 2MD 0.443609 0.858824
56 GDR 0.443548 0.924051
57 GFB 0.443548 0.924051
58 GTG 0.443548 0.949367
59 PGD O 0.442857 0.840909
60 GDX 0.440945 0.935897
61 G3A 0.44 0.961039
62 G U34 0.439394 0.901235
63 YGP 0.439024 0.890244
64 G5P 0.436508 0.961039
65 OMC OMU OMG OMG U 0.436242 0.902439
66 G1R G1R 0.435714 0.936709
67 MGD 0.433824 0.858824
68 CAG 0.433824 0.892857
69 JB2 0.433071 0.924051
70 GGM 0.432836 0.91358
71 DGI 0.429825 0.8875
72 GPD 0.429688 0.890244
73 DGP 0.427273 0.898734
74 DG 0.427273 0.898734
75 CG2 0.425373 0.901235
76 GPX 0.425 0.909091
77 DC DG 0.422222 0.879518
78 U2G 0.421053 0.901235
79 I2C FE2 CMO CMO 0.42029 0.820225
80 ZGP 0.41791 0.880952
81 P1G 0.415929 0.860759
82 DGT 0.415254 0.8875
83 JB3 0.413534 0.9125
84 GPC 0.413043 0.869048
85 P2G 0.410714 0.871795
86 FEG 0.410448 0.891566
87 NGD 0.410448 0.974026
88 GH3 0.408333 0.935065
89 DBG 0.405594 0.936709
90 5GP 5GP 0.405172 0.946667
Similar Binding Sites (Proteins are less than 50% similar to leader)
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