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Receptor
PDB id Resolution Class Description Source Keywords
4G9Z 2.03 Å NON-ENZYME: OTHER LASSA NUCLEOPROTEIN WITH DSRNA REVEALS NOVEL MECHANISM FOR I SUPPRESSION LASSA VIRUS STRUCTURAL GENOMICS SCOTTISH STRUCTURAL PROTEOMICS FACILITY3-prime -5-prime -RIBONUCLEASE NUCLEASE VIRAL PROTEIN-RNA COMPLEX
Ref.: STRUCTURES OF ARENAVIRAL NUCLEOPROTEINS WITH TRIPHO DSRNA REVEAL A UNIQUE MECHANISM OF IMMUNE SUPPRESSI J.BIOL.CHEM. V. 288 16949 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
G C C C E:4;
Valid;
none;
submit data
1259.75 n/a P(=O)...
G G G C F:4;
Valid;
none;
submit data
1339.8 n/a P(=O)...
ZN A:601;
Part of Protein;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4G9Z 2.03 Å NON-ENZYME: OTHER LASSA NUCLEOPROTEIN WITH DSRNA REVEALS NOVEL MECHANISM FOR I SUPPRESSION LASSA VIRUS STRUCTURAL GENOMICS SCOTTISH STRUCTURAL PROTEOMICS FACILITY3-prime -5-prime -RIBONUCLEASE NUCLEASE VIRAL PROTEIN-RNA COMPLEX
Ref.: STRUCTURES OF ARENAVIRAL NUCLEOPROTEINS WITH TRIPHO DSRNA REVEAL A UNIQUE MECHANISM OF IMMUNE SUPPRESSI J.BIOL.CHEM. V. 288 16949 2013
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 4G9Z - G G G C n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 4G9Z - G G G C n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 4G9Z - G G G C n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: G C C C ; Similar ligands found: 83
No: Ligand ECFP6 Tc MDL keys Tc
1 G C C C 1 1
2 G G G C 0.955357 0.987342
3 A G C C 0.896552 0.987179
4 G C 0.820513 0.974684
5 G G G RPC 0.789916 0.949367
6 G G 0.694915 0.949367
7 G U 0.661417 0.974684
8 A G U U 0.641379 0.9625
9 A C A C 0.619403 0.925
10 U A C C 0.619403 0.936709
11 A G U 0.618056 0.9625
12 GPC 0.61194 0.927711
13 C C C C 0.606838 0.860759
14 C C 0.594828 0.871795
15 A U C C 0.590278 0.925
16 U A A U 0.577465 0.936709
17 CG2 0.558824 0.9625
18 G A A A 0.550725 0.925
19 U A G G 0.535714 0.936709
20 A G 0.528571 0.936709
21 DG DC 0.520548 0.926829
22 U U 0.516129 0.846154
23 G3D 0.512 0.911392
24 GCP G 0.507692 0.898734
25 APC G U 0.496552 0.888889
26 U A 0.496552 0.936709
27 G4P 0.492188 0.911392
28 G U34 0.485915 0.9625
29 DC DG 0.479167 0.915663
30 0O2 0.477273 0.911392
31 ALF 5GP 0.472441 0.869048
32 U U U U 0.468254 0.833333
33 DA DC DG DA 0.467066 0.915663
34 3GP 0.46281 0.898734
35 U2G 0.458333 0.9625
36 CTP C C C C 0.457143 0.858974
37 CSV 0.451852 0.829268
38 CSQ 0.451852 0.829268
39 A U 0.451389 0.9
40 GDP AF3 0.451128 0.869048
41 GDP ALF 0.451128 0.869048
42 ALF GDP 0.451128 0.869048
43 5GP 0.443548 0.935897
44 G 0.443548 0.935897
45 UCG 0.43871 0.962025
46 GDP 0.4375 0.924051
47 GP2 0.4375 0.890244
48 A A 0.437037 0.873418
49 GCP 0.435115 0.901235
50 GNH 0.434109 0.9125
51 GPG 0.433824 0.91358
52 GDP 7MG 0.432624 0.91358
53 GSP 0.431818 0.879518
54 GP3 0.429688 0.925
55 CDP 0.42623 0.860759
56 C5P 0.423729 0.871795
57 C 0.423729 0.871795
58 CAR 0.423729 0.871795
59 CGP 0.422819 0.915663
60 GMV 0.416667 0.901235
61 GTP 0.416667 0.924051
62 2GP 0.416 0.8875
63 DC DG DA DC 0.415663 0.903614
64 GAV 0.414815 0.890244
65 7XL 0.414062 0.817073
66 G1R 0.413534 0.9125
67 GMP 0.411765 0.8125
68 DG DA DC DG 0.411765 0.904762
69 GNP 0.410448 0.901235
70 9GM 0.410448 0.901235
71 G2P 0.410448 0.890244
72 G2R 0.405797 0.890244
73 DC DG DT DA 0.405556 0.883721
74 HF4 0.404762 0.860759
75 CTP 0.404762 0.860759
76 CDC 0.402985 0.764045
77 UDP ALA FGA CYS DAL DAL MUB C C A9Z 0.401709 0.8
78 GDC 0.401408 0.91358
79 GKE 0.401408 0.91358
80 GDD 0.401408 0.91358
81 CDM 0.4 0.77907
82 DT DA DC DG 0.4 0.883721
83 JB2 0.4 0.91358
Ligand no: 2; Ligand: G G G C ; Similar ligands found: 98
No: Ligand ECFP6 Tc MDL keys Tc
1 G G G C 1 1
2 G C C C 0.955357 0.987342
3 G C 0.857143 0.9625
4 A G C C 0.853448 0.974684
5 G G G RPC 0.762712 0.962025
6 G G 0.725664 0.962025
7 G U 0.688525 0.9625
8 A G U 0.640288 0.975
9 GPC 0.635659 0.916667
10 A G U U 0.618056 0.975
11 A C A C 0.58209 0.9375
12 U A C C 0.58209 0.949367
13 G A A A 0.571429 0.9375
14 CG2 0.568182 0.950617
15 U A A U 0.564286 0.949367
16 C C C C 0.564103 0.85
17 U A G G 0.555556 0.949367
18 A U C C 0.555556 0.9375
19 C C 0.551724 0.860759
20 A G 0.548148 0.949367
21 DG DC 0.539007 0.915663
22 G3D 0.533333 0.9
23 GCP G 0.528 0.8875
24 APC G U 0.514286 0.901235
25 G4P 0.512195 0.9
26 G U34 0.50365 0.950617
27 U U 0.5 0.835443
28 DC DG 0.496403 0.904762
29 0O2 0.496063 0.9
30 ALF 5GP 0.491803 0.858824
31 3GP 0.482759 0.8875
32 U A 0.482517 0.949367
33 DA DC DG DA 0.481481 0.927711
34 GDP ALF 0.46875 0.858824
35 GDP AF3 0.46875 0.858824
36 ALF GDP 0.46875 0.858824
37 A U 0.467626 0.9125
38 U2G 0.464286 0.950617
39 5GP 0.462185 0.924051
40 G 0.462185 0.924051
41 GDP 0.455285 0.9125
42 GP2 0.455285 0.879518
43 A A 0.453846 0.886076
44 GCP 0.452381 0.890244
45 GNH 0.451613 0.901235
46 GPG 0.450382 0.925926
47 GSP 0.448819 0.869048
48 GDP 7MG 0.448529 0.925926
49 GP3 0.447154 0.9375
50 CSQ 0.44697 0.819277
51 CSV 0.44697 0.819277
52 CDP 0.444444 0.85
53 CAR 0.442478 0.860759
54 C5P 0.442478 0.860759
55 C 0.442478 0.860759
56 U U U U 0.44 0.822785
57 CGP 0.4375 0.904762
58 2GP 0.433333 0.876543
59 GTP 0.433071 0.9125
60 GMV 0.433071 0.890244
61 7XL 0.430894 0.807229
62 GAV 0.430769 0.879518
63 GMP 0.429825 0.802469
64 G1R 0.429688 0.901235
65 DC DG DA DC 0.428571 0.915663
66 9GM 0.426357 0.890244
67 G2P 0.426357 0.879518
68 GNP 0.426357 0.890244
69 UCG 0.424837 0.95
70 DG DA DC DG 0.424242 0.916667
71 HF4 0.421488 0.85
72 CTP 0.421488 0.85
73 CTP C C C C 0.421429 0.848101
74 G2R 0.421053 0.879518
75 CDC 0.418605 0.755556
76 DC DG DT DA 0.417143 0.895349
77 GDC 0.416058 0.902439
78 GKE 0.416058 0.902439
79 GDD 0.416058 0.902439
80 CDM 0.415385 0.770115
81 JB2 0.414286 0.902439
82 C5G 0.412214 0.829268
83 DT DA DC DG 0.411429 0.895349
84 6CK 0.410072 0.880952
85 CXY 0.409091 0.829268
86 DG DG 0.407407 0.880952
87 PGD O 0.406452 0.865169
88 Y9Z 0.405797 0.829545
89 GKD 0.404255 0.902439
90 BGO 0.40411 0.891566
91 91P 0.40411 0.951219
92 GDR 0.402878 0.902439
93 GFB 0.402878 0.902439
94 GTG 0.402878 0.926829
95 GDX 0.401408 0.91358
96 G1R G1R 0.4 0.914634
97 G3A 0.4 0.9375
98 TPG 0.4 0.835165
Similar Binding Sites (Proteins are less than 50% similar to leader) APoc FAQ
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