Receptor
PDB id Resolution Class Description Source Keywords
4G9Z 2.03 Å NON-ENZYME: OTHER LASSA NUCLEOPROTEIN WITH DSRNA REVEALS NOVEL MECHANISM FOR I SUPPRESSION LASSA VIRUS STRUCTURAL GENOMICS SCOTTISH STRUCTURAL PROTEOMICS FACILITY3-prime -5-prime -RIBONUCLEASE NUCLEASE VIRAL PROTEIN-RNA COMPLEX
Ref.: STRUCTURES OF ARENAVIRAL NUCLEOPROTEINS WITH TRIPHO DSRNA REVEAL A UNIQUE MECHANISM OF IMMUNE SUPPRESSI J.BIOL.CHEM. V. 288 16949 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
G C C C E:4;
Valid;
none;
submit data
1259.75 n/a [P+](...
G G G C F:4;
Valid;
none;
submit data
1339.8 n/a [P+](...
ZN A:601;
Part of Protein;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4G9Z 2.03 Å NON-ENZYME: OTHER LASSA NUCLEOPROTEIN WITH DSRNA REVEALS NOVEL MECHANISM FOR I SUPPRESSION LASSA VIRUS STRUCTURAL GENOMICS SCOTTISH STRUCTURAL PROTEOMICS FACILITY3-prime -5-prime -RIBONUCLEASE NUCLEASE VIRAL PROTEIN-RNA COMPLEX
Ref.: STRUCTURES OF ARENAVIRAL NUCLEOPROTEINS WITH TRIPHO DSRNA REVEAL A UNIQUE MECHANISM OF IMMUNE SUPPRESSI J.BIOL.CHEM. V. 288 16949 2013
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 4G9Z - G G G C n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 4G9Z - G G G C n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 4G9Z - G G G C n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: G C C C ; Similar ligands found: 82
No: Ligand ECFP6 Tc MDL keys Tc
1 G C C C 1 1
2 G G G C 0.955357 0.987342
3 A G C C 0.896552 0.987179
4 G C 0.820513 0.974684
5 G G G RPC 0.789916 0.949367
6 G G U 0.663934 0.936709
7 U A C C 0.619403 0.936709
8 A G U 0.618056 0.9625
9 GPC 0.61194 0.927711
10 OMC OMU OMG OMG U 0.609589 0.939024
11 G G 0.606557 0.936709
12 C C 0.594828 0.871795
13 A U C C 0.590278 0.925
14 U G A 0.581081 0.9625
15 U A A U 0.577465 0.936709
16 CG2 0.558824 0.9625
17 G A A A 0.550725 0.925
18 U A G G 0.535714 0.936709
19 DG DC 0.520548 0.926829
20 U U 0.516129 0.846154
21 G3D 0.512 0.911392
22 APC G U 0.496552 0.888889
23 G4P 0.492188 0.911392
24 G U34 0.485915 0.9625
25 DC DG 0.479167 0.915663
26 0O2 0.477273 0.911392
27 GDP MG 0.47619 0.901235
28 GDP BEF 0.472441 0.879518
29 ALF 5GP 0.472441 0.869048
30 U U U U 0.468254 0.833333
31 3GP 0.46281 0.898734
32 GTP MG 0.461538 0.901235
33 BEF GDP 0.461538 0.869048
34 U2G 0.458333 0.9625
35 CDP MG 0.458333 0.82716
36 CTP C C C C 0.457143 0.858974
37 CSQ 0.451852 0.829268
38 CSV 0.451852 0.829268
39 A U 0.451389 0.9
40 GDP AF3 0.451128 0.869048
41 GDP ALF 0.451128 0.869048
42 5GP 0.443548 0.935897
43 G 0.443548 0.935897
44 UCG 0.43871 0.962025
45 GDP 0.4375 0.924051
46 GP2 0.4375 0.890244
47 A A 0.437037 0.873418
48 GCP 0.435115 0.901235
49 GNH 0.434109 0.9125
50 GPG 0.433824 0.91358
51 GDP 7MG 0.432624 0.91358
52 GSP 0.431818 0.879518
53 GP3 0.429688 0.925
54 CDP 0.42623 0.860759
55 GCP G 0.425373 0.9125
56 C5P 0.423729 0.871795
57 C 0.423729 0.871795
58 CAR 0.423729 0.871795
59 CGP 0.422819 0.915663
60 DA DC DG DA 0.417647 0.904762
61 GTP 0.416667 0.924051
62 GMV 0.416667 0.901235
63 2GP 0.416 0.8875
64 DC DG DA DC 0.415663 0.903614
65 GAV 0.414815 0.890244
66 7XL 0.414062 0.817073
67 G1R 0.413534 0.9125
68 GMP 0.411765 0.8125
69 DG DA DC DG 0.411765 0.904762
70 GNP 0.410448 0.901235
71 G2P 0.410448 0.890244
72 I2C FE2 CMO CMO 0.409091 0.853933
73 G2R 0.405797 0.890244
74 DC DG DT DA 0.405556 0.883721
75 CTP 0.404762 0.860759
76 CDC 0.402985 0.764045
77 GDC 0.401408 0.91358
78 GDD 0.401408 0.91358
79 GKE 0.401408 0.91358
80 DT DA DC DG 0.4 0.883721
81 JB2 0.4 0.91358
82 CDM 0.4 0.77907
Ligand no: 2; Ligand: G G G C ; Similar ligands found: 98
No: Ligand ECFP6 Tc MDL keys Tc
1 G G G C 1 1
2 G C C C 0.955357 0.987342
3 G C 0.857143 0.9625
4 A G C C 0.853448 0.974684
5 G G G RPC 0.762712 0.962025
6 G G U 0.692308 0.949367
7 A G U 0.640288 0.975
8 GPC 0.635659 0.916667
9 G G 0.632479 0.949367
10 OMC OMU OMG OMG U 0.631206 0.951219
11 U G A 0.590278 0.975
12 U A C C 0.58209 0.949367
13 G A A A 0.571429 0.9375
14 CG2 0.568182 0.950617
15 U A A U 0.564286 0.949367
16 U A G G 0.555556 0.949367
17 A U C C 0.555556 0.9375
18 C C 0.551724 0.860759
19 DG DC 0.539007 0.915663
20 G3D 0.533333 0.9
21 APC G U 0.514286 0.901235
22 G4P 0.512195 0.9
23 G U34 0.50365 0.950617
24 U U 0.5 0.835443
25 DC DG 0.496403 0.904762
26 0O2 0.496063 0.9
27 GDP MG 0.495868 0.890244
28 GDP BEF 0.491803 0.869048
29 ALF 5GP 0.491803 0.858824
30 3GP 0.482759 0.8875
31 BEF GDP 0.48 0.858824
32 GTP MG 0.48 0.890244
33 CDP MG 0.478261 0.817073
34 GDP ALF 0.46875 0.858824
35 GDP AF3 0.46875 0.858824
36 A U 0.467626 0.9125
37 U2G 0.464286 0.950617
38 G 0.462185 0.924051
39 5GP 0.462185 0.924051
40 GDP 0.455285 0.9125
41 GP2 0.455285 0.879518
42 A A 0.453846 0.886076
43 GCP 0.452381 0.890244
44 GNH 0.451613 0.901235
45 GPG 0.450382 0.925926
46 GSP 0.448819 0.869048
47 GDP 7MG 0.448529 0.925926
48 GP3 0.447154 0.9375
49 CSQ 0.44697 0.819277
50 CSV 0.44697 0.819277
51 CDP 0.444444 0.85
52 C5P 0.442478 0.860759
53 C 0.442478 0.860759
54 CAR 0.442478 0.860759
55 GCP G 0.44186 0.901235
56 U U U U 0.44 0.822785
57 CGP 0.4375 0.904762
58 2GP 0.433333 0.876543
59 GTP 0.433071 0.9125
60 GMV 0.433071 0.890244
61 7XL 0.430894 0.807229
62 GAV 0.430769 0.879518
63 DA DC DG DA 0.430303 0.916667
64 GMP 0.429825 0.802469
65 G1R 0.429688 0.901235
66 DC DG DA DC 0.428571 0.915663
67 G2P 0.426357 0.879518
68 GNP 0.426357 0.890244
69 UCG 0.424837 0.95
70 DG DA DC DG 0.424242 0.916667
71 I2C FE2 CMO CMO 0.422819 0.844444
72 CTP 0.421488 0.85
73 CTP C C C C 0.421429 0.848101
74 G2R 0.421053 0.879518
75 CDC 0.418605 0.755556
76 DC DG DT DA 0.417143 0.895349
77 GDC 0.416058 0.902439
78 GDD 0.416058 0.902439
79 GKE 0.416058 0.902439
80 CDM 0.415385 0.770115
81 JB2 0.414286 0.902439
82 C5G 0.412214 0.829268
83 DT DA DC DG 0.411429 0.895349
84 6CK 0.410072 0.880952
85 CXY 0.409091 0.829268
86 DG DG 0.407407 0.880952
87 PGD O 0.406452 0.865169
88 Y9Z 0.405797 0.829545
89 GKD 0.404255 0.902439
90 91P 0.40411 0.951219
91 BGO 0.40411 0.891566
92 GFB 0.402878 0.902439
93 GDR 0.402878 0.902439
94 GTG 0.402878 0.926829
95 GDX 0.401408 0.91358
96 TPG 0.4 0.835165
97 G1R G1R 0.4 0.914634
98 G3A 0.4 0.9375
Similar Binding Sites (Proteins are less than 50% similar to leader)
Feedback