Receptor
PDB id Resolution Class Description Source Keywords
4H3K 2 Å EC: 3.1.3.16 CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF HUMAN SYMPLEKIN NT SSU72 AND A RNA POLYMERASE II CTD PEPTIDE PHOSPHORYLATED ATS ER-5 AND SER-7 HOMO SAPIENS HEAT REPEAT PHOSPHATASE RNA POLYMERASE II HYDROLASE
Ref.: AN UNEXPECTED BINDING MODE FOR A POL II CTD PEPTIDE PHOSPHORYLATED AT SER7 IN THE ACTIVE SITE OF THE CT PHOSPHATASE SSU72. GENES DEV. V. 26 2265 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PO4 B:201;
 Invalid;
 none;
 submit data
94.971 O4 P [O-]P...
SER TYR SEP PRO THR SEP PRO SEP TYR SER F:2;
 Valid;
 none;
 submit data
n/a n/a
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3O2Q 2.4 Å EC: 3.1.3.16 CRYSTAL STRUCTURE OF THE HUMAN SYMPLEKIN-SSU72-CTD PHOSPHOPE COMPLEX HOMO SAPIENS HEAT REPEAT SCAFFOLD PHOSPHATASE POLYMERASE II CTD CIS-PHYDROLASE
Ref.: CRYSTAL STRUCTURE OF THE HUMAN SYMPLEKIN-SSU72-CTD PHOSPHOPEPTIDE COMPLEX. NATURE V. 467 729 2010
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 24 families.
1 3O2Q - PRO THR SEP PRO SER TYR n/a n/a
2 4H3K - SER TYR SEP PRO THR SEP PRO SEP TYR SER n/a n/a
3 4H3H - SER PRO THR SER PRO SEP TYR SER PRO PRO n/a n/a
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 18 families.
1 3O2Q - PRO THR SEP PRO SER TYR n/a n/a
2 4H3K - SER TYR SEP PRO THR SEP PRO SEP TYR SER n/a n/a
3 4H3H - SER PRO THR SER PRO SEP TYR SER PRO PRO n/a n/a
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 13 families.
1 3O2Q - PRO THR SEP PRO SER TYR n/a n/a
2 4H3K - SER TYR SEP PRO THR SEP PRO SEP TYR SER n/a n/a
3 4H3H - SER PRO THR SER PRO SEP TYR SER PRO PRO n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: SER TYR SEP PRO THR SEP PRO SEP TYR SER; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Ligands (3D)
Ligand no: 1; Ligand: SER TYR SEP PRO THR SEP PRO SEP TYR SER; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3O2Q; Ligand: PRO THR SEP PRO SER TYR; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 3o2q.bio2) has 21 residues
No: Leader PDB Ligand Sequence Similarity
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