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Receptor

PDB id	Resolution	Class	Description	Source	Keywords
4HGF	1.7 Å	EC: 1.14.14.1	CRYSTAL STRUCTURE OF P450 BM3 5F5K HEME DOMAIN VARIANT COMPL STYRENE	BACILLUS MEGATERIUM	OXIDOREDUCTASE P450 BM3 HEMOPROTEIN STYRENE EPOXIDATION ENANTIOSELECTIVITY HEME BINDING
Ref.:	P450 BM3 CRYSTAL STRUCTURES REVEAL THE ROLE OF THE SURFACE RESIDUE LYS/ARG184 IN INVERSION OF ENANTIOS STYRENE EPOXIDATION. CHEM.COMMUN.(CAMB.) V. 49 4694 2013

Ligand

Ligand	Chain:Residue	Validity	Ligand Warnings	Binding Data	Molecular Weight (Da)	Formula	SMILES
HEM	B:501; A:501;	Part of Protein; Part of Protein;	none; none;	submit data	616.487	C34 H32 Fe N4 O4	Cc1c2...
CL	A:503;	Invalid;	none;	submit data	35.453	Cl	[Cl-]
SYN	B:502; A:502;	Valid; Valid;	none; none;	submit data	104.149	C8 H8	C=Cc1...

View in 3D viewer

90% Homology Family

Leader

PDB id	Resolution	Class	Description	Source	Keywords
1ZOA	1.74 Å	EC: 1.14.14.1	CRYSTAL STRUCTURE OF A328V MUTANT OF THE HEME DOMAIN OF P450 N-PALMITOYLGLYCINE	BACILLUS MEGATERIUM	CYTOCHROME P-450 HEMEPROTEIN A328V OXIDOREDUCTASE
Ref.:	A SINGLE ACTIVE-SITE MUTATION OF P450BM-3 DRAMATICA ENHANCES SUBSTRATE BINDING AND RATE OF PRODUCT FORM BIOCHEMISTRY V. 50 8333 2011

Members (38)

No:	PDB id	Binding Data	Representative ligand	Formula	Smiles
The Class containing this family consists of a total of 9 families.
1	6H1L	Kd = 24.5 uM	FJQ	C16 H13 Cl3 N2 O S	c1cc(c(cc1....
2	1JPZ	Kd = 262 nM	140	C18 H35 N O3	CCCCCCCCCC....
3	6JZS	-	WAA	C31 H40 N2 O3	CC(C)C1=CC....
4	3EKD	Kd = 7.4 uM	PAM	C16 H30 O2	CCCCCCC=C/....
5	6K24	-	WAA	C31 H40 N2 O3	CC(C)C1=CC....
6	4KEW	Kd = 1.67 uM	1C6	C17 H19 N3 O2 S	Cc1cnc(c(c....
7	4HGG	-	SYN	C8 H8	C=Cc1ccccc....
8	5XA3	-	PRO PHQ PHE	n/a	n/a
9	4DTW	Kd = 80 uM	SRO	C10 H12 N2 O	c1cc2c(cc1....
10	6H1O	-	VOR	C16 H14 F3 N5 O	C[C@@H](c1....
11	4KEY	Kd = 0.212 uM	1C6	C17 H19 N3 O2 S	Cc1cnc(c(c....
12	4O4P	-	1C6	C17 H19 N3 O2 S	Cc1cnc(c(c....
13	6JS8	-	C5R	C31 H38 N2 O3	CC(C)c1ccc....
14	4HGH	-	SYN	C8 H8	C=Cc1ccccc....
15	4DTZ	Kd = 8.9 uM	LDP	C8 H11 N O2	c1cc(c(cc1....
16	5DYZ	Kd = 0.54 uM	140	C18 H35 N O3	CCCCCCCCCC....
17	4DUB	Kd = 1.3 uM	LDP	C8 H11 N O2	c1cc(c(cc1....
18	3BEN	Kd = 0.32 uM	LEH	C21 H37 N3 O3	CC(C)C[C@@....
19	5JQ2	-	140	C18 H35 N O3	CCCCCCCCCC....
20	6LY4	-	TES	C19 H28 O2	C[C@]12CC[....
21	4HGI	-	SYN	C8 H8	C=Cc1ccccc....
22	4DUF	Kd = 3.3 uM	SRO	C10 H12 N2 O	c1cc2c(cc1....
23	3KX3	-	140	C18 H35 N O3	CCCCCCCCCC....
24	6JLV	-	WAA	C31 H40 N2 O3	CC(C)C1=CC....
25	4KPA	Kd = 0.37 uM	140	C18 H35 N O3	CCCCCCCCCC....
26	6H1T	Kd = 32.8 uM	CL6	C22 H17 Cl N2	c1ccc(cc1)....
27	4HGF	-	SYN	C8 H8	C=Cc1ccccc....
28	6K58	-	D0L	C21 H32 N2 O3	CCCCCCCN1C....
29	1ZO9	-	EPM	C21 H41 N O3 S	CCCCCCCCCC....
30	4DU2	Kd = 3.3 uM	LDP	C8 H11 N O2	c1cc(c(cc1....
31	6JVC	-	WAA	C31 H40 N2 O3	CC(C)C1=CC....
32	6JMH	-	WAA	C31 H40 N2 O3	CC(C)C1=CC....
33	6K9S	-	WAA	C31 H40 N2 O3	CC(C)C1=CC....
34	6H1S	-	TPF	C13 H12 F2 N6 O	c1cc(c(cc1....
35	4DUE	Kd = 0.7 uM	SRO	C10 H12 N2 O	c1cc2c(cc1....
36	6JO1	-	BWX	C22 H27 N O3	C[C@@H](c1....
37	6JMW	-	WAA	C31 H40 N2 O3	CC(C)C1=CC....
38	1ZOA	Kd = 45 nM	140	C18 H35 N O3	CCCCCCCCCC....

70% Homology Family (38)

No:	PDB id	Binding Data	Representative ligand	Formula	Smiles
The Class containing this family consists of a total of 6 families.
1	6H1L	Kd = 24.5 uM	FJQ	C16 H13 Cl3 N2 O S	c1cc(c(cc1....
2	1JPZ	Kd = 262 nM	140	C18 H35 N O3	CCCCCCCCCC....
3	6JZS	-	WAA	C31 H40 N2 O3	CC(C)C1=CC....
4	3EKD	Kd = 7.4 uM	PAM	C16 H30 O2	CCCCCCC=C/....
5	6K24	-	WAA	C31 H40 N2 O3	CC(C)C1=CC....
6	4KEW	Kd = 1.67 uM	1C6	C17 H19 N3 O2 S	Cc1cnc(c(c....
7	4HGG	-	SYN	C8 H8	C=Cc1ccccc....
8	5XA3	-	PRO PHQ PHE	n/a	n/a
9	4DTW	Kd = 80 uM	SRO	C10 H12 N2 O	c1cc2c(cc1....
10	6H1O	-	VOR	C16 H14 F3 N5 O	C[C@@H](c1....
11	4KEY	Kd = 0.212 uM	1C6	C17 H19 N3 O2 S	Cc1cnc(c(c....
12	4O4P	-	1C6	C17 H19 N3 O2 S	Cc1cnc(c(c....
13	6JS8	-	C5R	C31 H38 N2 O3	CC(C)c1ccc....
14	4HGH	-	SYN	C8 H8	C=Cc1ccccc....
15	4DTZ	Kd = 8.9 uM	LDP	C8 H11 N O2	c1cc(c(cc1....
16	5DYZ	Kd = 0.54 uM	140	C18 H35 N O3	CCCCCCCCCC....
17	4DUB	Kd = 1.3 uM	LDP	C8 H11 N O2	c1cc(c(cc1....
18	3BEN	Kd = 0.32 uM	LEH	C21 H37 N3 O3	CC(C)C[C@@....
19	5JQ2	-	140	C18 H35 N O3	CCCCCCCCCC....
20	6LY4	-	TES	C19 H28 O2	C[C@]12CC[....
21	4HGI	-	SYN	C8 H8	C=Cc1ccccc....
22	4DUF	Kd = 3.3 uM	SRO	C10 H12 N2 O	c1cc2c(cc1....
23	3KX3	-	140	C18 H35 N O3	CCCCCCCCCC....
24	6JLV	-	WAA	C31 H40 N2 O3	CC(C)C1=CC....
25	4KPA	Kd = 0.37 uM	140	C18 H35 N O3	CCCCCCCCCC....
26	6H1T	Kd = 32.8 uM	CL6	C22 H17 Cl N2	c1ccc(cc1)....
27	4HGF	-	SYN	C8 H8	C=Cc1ccccc....
28	6K58	-	D0L	C21 H32 N2 O3	CCCCCCCN1C....
29	1ZO9	-	EPM	C21 H41 N O3 S	CCCCCCCCCC....
30	4DU2	Kd = 3.3 uM	LDP	C8 H11 N O2	c1cc(c(cc1....
31	6JVC	-	WAA	C31 H40 N2 O3	CC(C)C1=CC....
32	6JMH	-	WAA	C31 H40 N2 O3	CC(C)C1=CC....
33	6K9S	-	WAA	C31 H40 N2 O3	CC(C)C1=CC....
34	6H1S	-	TPF	C13 H12 F2 N6 O	c1cc(c(cc1....
35	4DUE	Kd = 0.7 uM	SRO	C10 H12 N2 O	c1cc2c(cc1....
36	6JO1	-	BWX	C22 H27 N O3	C[C@@H](c1....
37	6JMW	-	WAA	C31 H40 N2 O3	CC(C)C1=CC....
38	1ZOA	Kd = 45 nM	140	C18 H35 N O3	CCCCCCCCCC....

50% Homology Family (38)

No:	PDB id	Binding Data	Representative ligand	Formula	Smiles
The Class containing this family consists of a total of 5 families.
1	6H1L	Kd = 24.5 uM	FJQ	C16 H13 Cl3 N2 O S	c1cc(c(cc1....
2	1JPZ	Kd = 262 nM	140	C18 H35 N O3	CCCCCCCCCC....
3	6JZS	-	WAA	C31 H40 N2 O3	CC(C)C1=CC....
4	3EKD	Kd = 7.4 uM	PAM	C16 H30 O2	CCCCCCC=C/....
5	6K24	-	WAA	C31 H40 N2 O3	CC(C)C1=CC....
6	4KEW	Kd = 1.67 uM	1C6	C17 H19 N3 O2 S	Cc1cnc(c(c....
7	4HGG	-	SYN	C8 H8	C=Cc1ccccc....
8	5XA3	-	PRO PHQ PHE	n/a	n/a
9	4DTW	Kd = 80 uM	SRO	C10 H12 N2 O	c1cc2c(cc1....
10	6H1O	-	VOR	C16 H14 F3 N5 O	C[C@@H](c1....
11	4KEY	Kd = 0.212 uM	1C6	C17 H19 N3 O2 S	Cc1cnc(c(c....
12	4O4P	-	1C6	C17 H19 N3 O2 S	Cc1cnc(c(c....
13	6JS8	-	C5R	C31 H38 N2 O3	CC(C)c1ccc....
14	4HGH	-	SYN	C8 H8	C=Cc1ccccc....
15	4DTZ	Kd = 8.9 uM	LDP	C8 H11 N O2	c1cc(c(cc1....
16	5DYZ	Kd = 0.54 uM	140	C18 H35 N O3	CCCCCCCCCC....
17	4DUB	Kd = 1.3 uM	LDP	C8 H11 N O2	c1cc(c(cc1....
18	3BEN	Kd = 0.32 uM	LEH	C21 H37 N3 O3	CC(C)C[C@@....
19	5JQ2	-	140	C18 H35 N O3	CCCCCCCCCC....
20	6LY4	-	TES	C19 H28 O2	C[C@]12CC[....
21	4HGI	-	SYN	C8 H8	C=Cc1ccccc....
22	4DUF	Kd = 3.3 uM	SRO	C10 H12 N2 O	c1cc2c(cc1....
23	3KX3	-	140	C18 H35 N O3	CCCCCCCCCC....
24	6JLV	-	WAA	C31 H40 N2 O3	CC(C)C1=CC....
25	4KPA	Kd = 0.37 uM	140	C18 H35 N O3	CCCCCCCCCC....
26	6H1T	Kd = 32.8 uM	CL6	C22 H17 Cl N2	c1ccc(cc1)....
27	4HGF	-	SYN	C8 H8	C=Cc1ccccc....
28	6K58	-	D0L	C21 H32 N2 O3	CCCCCCCN1C....
29	1ZO9	-	EPM	C21 H41 N O3 S	CCCCCCCCCC....
30	4DU2	Kd = 3.3 uM	LDP	C8 H11 N O2	c1cc(c(cc1....
31	6JVC	-	WAA	C31 H40 N2 O3	CC(C)C1=CC....
32	6JMH	-	WAA	C31 H40 N2 O3	CC(C)C1=CC....
33	6K9S	-	WAA	C31 H40 N2 O3	CC(C)C1=CC....
34	6H1S	-	TPF	C13 H12 F2 N6 O	c1cc(c(cc1....
35	4DUE	Kd = 0.7 uM	SRO	C10 H12 N2 O	c1cc2c(cc1....
36	6JO1	-	BWX	C22 H27 N O3	C[C@@H](c1....
37	6JMW	-	WAA	C31 H40 N2 O3	CC(C)C1=CC....
38	1ZOA	Kd = 45 nM	140	C18 H35 N O3	CCCCCCCCCC....

Polypharmacology

Similar Ligands (2D)

Ligand no: 1; Ligand: SYN; Similar ligands found: 1

No:	Ligand	ECFP6 Tc	MDL keys Tc
1	SYN	1	1

Similar Ligands (3D)

Ligand no: 1; Ligand: SYN; Similar ligands found: 1104

No:	Ligand	Similarity coefficient
1	AMC	1.0296
2	ABN	1.0000
3	9CL	1.0000
4	B24	1.0000
5	282	1.0000
6	1MR	1.0000
7	NBE	1.0000
8	HBX	1.0000
9	PYJ	1.0000
10	FPI	1.0000
11	APY	0.9984
12	PY7	0.9982
13	PYF	0.9972
14	JZ7	0.9900
15	L60	0.9830
16	BVC	0.9818
17	NVI	0.9815
18	1PT	0.9802
19	93B	0.9800
20	MZ0	0.9796
21	NIO	0.9795
22	IPH	0.9791
23	BEN	0.9791
24	CYH	0.9787
25	HAI	0.9783
26	PRI	0.9783
27	HVQ	0.9782
28	6PC	0.9781
29	2IM	0.9774
30	BEZ	0.9774
31	CXL	0.9769
32	HY1	0.9768
33	NCA	0.9768
34	BAM	0.9768
35	YCP	0.9757
36	271	0.9751
37	PBC	0.9750
38	FAN	0.9747
39	GXE	0.9743
40	HBA	0.9736
41	BVG	0.9730
42	PEL	0.9728
43	RSO	0.9727
44	1DU	0.9721
45	PEA	0.9714
46	TTO	0.9713
47	V1L	0.9707
48	2EZ	0.9699
49	278	0.9699
50	PZA	0.9699
51	UNU	0.9695
52	NBZ	0.9693
53	QSC	0.9687
54	M58	0.9687
55	JZ3	0.9685
56	MZW	0.9676
57	CXF	0.9676
58	BP9	0.9676
59	4JU	0.9674
60	JZ5	0.9674
61	NTN	0.9674
62	4VP	0.9670
63	AC0	0.9669
64	R8A	0.9669
65	JBN	0.9669
66	SS1	0.9663
67	IDM	0.9657
68	FBA	0.9655
69	8CL	0.9655
70	LDU	0.9654
71	A2Q	0.9653
72	FOA	0.9650
73	NK	0.9647
74	PRO	0.9646
75	2MH	0.9645
76	MBN	0.9643
77	DEN	0.9643
78	286	0.9638
79	HGW	0.9638
80	VGL	0.9634
81	PIH	0.9632
82	1AB	0.9632
83	280	0.9628
84	9PO	0.9628
85	2AP	0.9627
86	3AP	0.9626
87	IT2	0.9625
88	HSM	0.9625
89	PYC	0.9625
90	2PC	0.9623
91	SS2	0.9620
92	WOT	0.9619
93	9X7	0.9619
94	BZF	0.9618
95	HHN	0.9617
96	HVK	0.9616
97	HRZ	0.9616
98	EDG	0.9615
99	R2B	0.9614
100	4JM	0.9611
101	CEE	0.9610
102	JZ1	0.9610
103	ECE	0.9608
104	IND	0.9608
105	OHG	0.9606
106	4AP	0.9606
107	4JL	0.9597
108	LZ1	0.9595
109	TZC	0.9595
110	BZI	0.9589
111	0R1	0.9586
112	MRY	0.9584
113	HPY	0.9584
114	PHB	0.9583
115	URA	0.9582
116	RP7	0.9580
117	4JP	0.9579
118	4CH	0.9579
119	LGA	0.9578
120	ICC	0.9575
121	BE7	0.9575
122	BNS	0.9574
123	2KT	0.9574
124	GVH	0.9573
125	69O	0.9571
126	BML	0.9567
127	LG4	0.9567
128	MPI	0.9563
129	51F	0.9562
130	4HS	0.9558
131	AHR	0.9555
132	PCR	0.9554
133	OXQ	0.9554
134	OXZ	0.9553
135	URF	0.9549
136	0R0	0.9548
137	IFM	0.9548
138	J1Z	0.9548
139	26D	0.9548
140	PLQ	0.9544
141	273	0.9544
142	HQE	0.9542
143	MCT	0.9539
144	C2A	0.9539
145	SMV	0.9539
146	DA1	0.9538
147	FPN	0.9532
148	TP5	0.9531
149	WBU	0.9531
150	PXY	0.9530
151	H3M	0.9527
152	25R	0.9527
153	RCO	0.9526
154	C2B	0.9524
155	IMR	0.9524
156	HSE	0.9523
157	HGQ	0.9520
158	CRS	0.9519
159	GAG	0.9518
160	285	0.9517
161	R1X	0.9516
162	0CT	0.9516
163	SMB	0.9515
164	H8N	0.9511
165	5AC	0.9511
166	4XR	0.9510
167	C21	0.9509
168	TZE	0.9509
169	CYS	0.9509
170	265	0.9506
171	JAB	0.9505
172	2AC	0.9496
173	FPY	0.9496
174	1MC	0.9495
175	CYT	0.9493
176	RIB	0.9490
177	MZG	0.9489
178	4CL	0.9487
179	HEW	0.9485
180	NVA	0.9484
181	RSF	0.9481
182	4HO	0.9479
183	4ZE	0.9478
184	B3R	0.9477
185	4JN	0.9477
186	284	0.9476
187	LG3	0.9475
188	BVF	0.9475
189	GBD	0.9473
190	3CH	0.9473
191	MLI	0.9473
192	JZ9	0.9472
193	HCS	0.9472
194	CEJ	0.9471
195	CIG	0.9470
196	DPR	0.9470
197	HUI	0.9469
198	DAB	0.9468
199	23A	0.9466
200	IOL	0.9466
201	7EX	0.9464
202	DMG	0.9462
203	9YL	0.9460
204	A1U	0.9460
205	27Y	0.9460
206	KOJ	0.9459
207	QOS	0.9458
208	4JJ	0.9458
209	HY3	0.9458
210	BR9	0.9456
211	LG5	0.9455
212	MRZ	0.9453
213	AGK	0.9453
214	MLA	0.9451
215	HIU	0.9446
216	DGY	0.9443
217	03W	0.9443
218	8GF	0.9439
219	FP1	0.9438
220	HHQ	0.9438
221	DUC	0.9438
222	4H2	0.9437
223	TFB	0.9437
224	ABA	0.9434
225	VNJ	0.9432
226	PRS	0.9429
227	PYD	0.9429
228	ICP	0.9429
229	M3T	0.9428
230	4XX	0.9428
231	SAL	0.9427
232	MWJ	0.9425
233	BE2	0.9425
234	GIF	0.9424
235	MWM	0.9419
236	60P	0.9419
237	2DR	0.9419
238	JZ2	0.9418
239	ALO	0.9416
240	TDR	0.9415
241	23W	0.9415
242	261	0.9414
243	XYD	0.9414
244	AZF	0.9414
245	1DH	0.9411
246	3U4	0.9410
247	270	0.9410
248	AX7	0.9410
249	HYN	0.9409
250	XM0	0.9405
251	5JC	0.9404
252	BAQ	0.9403
253	3PY	0.9402
254	2LP	0.9398
255	XBZ	0.9397
256	7WG	0.9396
257	FEH	0.9395
258	34A	0.9394
259	1LN	0.9393
260	ES6	0.9393
261	ABV	0.9393
262	JZ4	0.9390
263	OAA	0.9388
264	LER	0.9387
265	XIX	0.9386
266	BSX	0.9384
267	TM7	0.9384
268	DCY	0.9382
269	C2N	0.9382
270	NPO	0.9382
271	MAK	0.9379
272	E60	0.9376
273	Z82	0.9376
274	GBL	0.9373
275	P92	0.9372
276	T2C	0.9371
277	JBE	0.9370
278	LMR	0.9369
279	2YU	0.9368
280	MB3	0.9367
281	2MP	0.9365
282	25T	0.9364
283	NEQ	0.9364
284	IDH	0.9364
285	2MI	0.9364
286	ATQ	0.9361
287	40E	0.9359
288	QY9	0.9358
289	717	0.9356
290	HT4	0.9354
291	I1E	0.9353
292	BZX	0.9353
293	NMJ	0.9353
294	4SV	0.9346
295	6X8	0.9346
296	DFB	0.9344
297	3ZQ	0.9344
298	49F	0.9342
299	HX3	0.9341
300	M6W	0.9339
301	0TR	0.9339
302	24T	0.9338
303	ASO	0.9337
304	2CH	0.9337
305	8GC	0.9336
306	PCA	0.9336
307	3XX	0.9335
308	5UC	0.9334
309	NIZ	0.9333
310	THE	0.9332
311	PRY	0.9331
312	KSW	0.9331
313	DSN	0.9331
314	ZBT	0.9329
315	3AB	0.9329
316	CFI	0.9327
317	SVN	0.9326
318	3HB	0.9323
319	HDA	0.9320
320	PAB	0.9319
321	HPA	0.9318
322	FBJ	0.9317
323	Y8I	0.9317
324	5MH	0.9316
325	P2D	0.9316
326	GAB	0.9315
327	3NT	0.9314
328	DTL	0.9314
329	4CS	0.9314
330	KG7	0.9314
331	BHO	0.9312
332	HX2	0.9310
333	4FA	0.9309
334	VAL	0.9307
335	YRL	0.9306
336	BEW	0.9306
337	AC6	0.9305
338	5MI	0.9305
339	HZP	0.9305
340	XYP	0.9305
341	C5J	0.9305
342	ISZ	0.9304
343	TMZ	0.9303
344	SER	0.9303
345	TH0	0.9303
346	ADE	0.9303
347	FW5	0.9303
348	HBD	0.9303
349	53C	0.9302
350	KIV	0.9301
351	3OC	0.9298
352	PAC	0.9298
353	AEF	0.9297
354	VKC	0.9295
355	3SK	0.9295
356	5H1	0.9294
357	FBM	0.9293
358	1Y6	0.9293
359	54D	0.9292
360	5MB	0.9292
361	6AI	0.9291
362	F9P	0.9289
363	XAP	0.9289
364	IP0	0.9288
365	LXC	0.9288
366	HTS	0.9287
367	10L	0.9286
368	TZL	0.9285
369	TPA	0.9285
370	CIZ	0.9284
371	WCE	0.9283
372	3BZ	0.9282
373	VAH	0.9281
374	6M9	0.9281
375	F81	0.9281
376	14O	0.9280
377	4MA	0.9280
378	47J	0.9277
379	43M	0.9276
380	5HN	0.9275
381	9DA	0.9274
382	1WD	0.9274
383	JKE	0.9274
384	HYP	0.9273
385	7CZ	0.9273
386	2K4	0.9272
387	XBT	0.9271
388	UY7	0.9271
389	938	0.9270
390	ASN	0.9270
391	PBZ	0.9269
392	PZI	0.9267
393	HSL	0.9267
394	Z6J	0.9266
395	SWD	0.9265
396	FUB	0.9263
397	MLM	0.9263
398	ES9	0.9263
399	CAQ	0.9262
400	AKB	0.9262
401	ILE	0.9260
402	OVV	0.9259
403	1CB	0.9258
404	GLC	0.9257
405	14J	0.9256
406	F05	0.9256
407	7A8	0.9255
408	93Q	0.9253
409	DXX	0.9252
410	YHO	0.9251
411	7WV	0.9251
412	F60	0.9251
413	HLR	0.9251
414	7HP	0.9250
415	MLT	0.9250
416	P72	0.9249
417	0RW	0.9248
418	RBJ	0.9247
419	JZ0	0.9247
420	QUZ	0.9246
421	THR	0.9245
422	PYG	0.9244
423	JFJ	0.9243
424	IQ0	0.9243
425	FYU	0.9241
426	BRT	0.9240
427	LCN	0.9240
428	G2F	0.9240
429	MMZ	0.9240
430	S76	0.9238
431	6M4	0.9237
432	BP1	0.9237
433	8EZ	0.9236
434	3MT	0.9236
435	2CK	0.9236
436	8LG	0.9235
437	9HX	0.9235
438	7WA	0.9234
439	MXN	0.9234
440	268	0.9233
441	HMH	0.9233
442	9EW	0.9232
443	TMT	0.9231
444	UGC	0.9229
445	NPY	0.9228
446	UYA	0.9226
447	P3K	0.9226
448	XYS	0.9225
449	LEA	0.9224
450	CRN	0.9224
451	MZY	0.9222
452	6MP	0.9222
453	RUU	0.9222
454	NOY	0.9222
455	11S	0.9221
456	DTU	0.9220
457	TH7	0.9220
458	2RH	0.9218
459	4MZ	0.9216
460	PBE	0.9215
461	AAE	0.9214
462	FP2	0.9213
463	FQI	0.9212
464	1DJ	0.9212
465	PYZ	0.9211
466	DE2	0.9209
467	NSP	0.9207
468	MAE	0.9206
469	ES4	0.9205
470	PM6	0.9205
471	O7U	0.9203
472	2XX	0.9202
473	MNN	0.9202
474	1AN	0.9202
475	HIO	0.9201
476	4JO	0.9201
477	6SP	0.9200
478	NOJ	0.9200
479	258	0.9198
480	SPA	0.9198
481	DHR	0.9198
482	JAE	0.9197
483	3MC	0.9195
484	H4N	0.9195
485	FK1	0.9195
486	3TR	0.9193
487	M4T	0.9193
488	NYL	0.9192
489	40O	0.9192
490	4AX	0.9192
491	24B	0.9191
492	4DX	0.9191
493	TEO	0.9190
494	260	0.9190
495	7N0	0.9189
496	OXE	0.9189
497	ASP	0.9186
498	NMG	0.9184
499	OK7	0.9184
500	6MH	0.9184
501	2MZ	0.9183
502	SW7	0.9181
503	BTE	0.9180
504	76X	0.9179
505	5MP	0.9179
506	TM4	0.9178
507	KYD	0.9178
508	BYZ	0.9177
509	HMU	0.9175
510	ZZ3	0.9175
511	1DQ	0.9175
512	ITN	0.9174
513	IF7	0.9174
514	92Z	0.9173
515	5KX	0.9173
516	826	0.9172
517	IFL	0.9172
518	FUM	0.9169
519	SIN	0.9169
520	3CE	0.9169
521	AMT	0.9165
522	MBD	0.9165
523	ABU	0.9165
524	L3Q	0.9164
525	1XX	0.9162
526	PMB	0.9162
527	ES3	0.9161
528	CSS	0.9157
529	URS	0.9156
530	2A7	0.9154
531	MR3	0.9153
532	1SP	0.9153
533	RIP	0.9153
534	FB2	0.9152
535	IUR	0.9150
536	ORN	0.9148
537	DGJ	0.9148
538	1MZ	0.9148
539	JZ6	0.9147
540	DAS	0.9146
541	174	0.9145
542	GOL	0.9144
543	I4B	0.9143
544	SGL	0.9142
545	3FA	0.9140
546	ZZT	0.9139
547	GJZ	0.9139
548	8H8	0.9139
549	Q88	0.9137
550	HOW	0.9131
551	IVA	0.9131
552	6UA	0.9131
553	SSN	0.9130
554	GXV	0.9129
555	2AF	0.9127
556	275	0.9125
557	G4D	0.9124
558	4NC	0.9123
559	SAR	0.9122
560	PHU	0.9121
561	2C9	0.9120
562	DFU	0.9120
563	DYA	0.9117
564	TLD	0.9117
565	2AI	0.9117
566	COI	0.9114
567	NLE	0.9113
568	A3B	0.9112
569	DBB	0.9112
570	98J	0.9110
571	YAN	0.9110
572	FFP	0.9109
573	HHA	0.9109
574	DMJ	0.9108
575	1P3	0.9108
576	BUA	0.9105
577	GMN	0.9104
578	8NY	0.9103
579	SHA	0.9101
580	FLM	0.9100
581	LT1	0.9099
582	2CM	0.9099
583	2RA	0.9098
584	ES0	0.9097
585	XYL	0.9096
586	RB5	0.9096
587	NXA	0.9095
588	2MY	0.9093
589	MAN	0.9093
590	L89	0.9092
591	MNM	0.9092
592	GYE	0.9091
593	AOA	0.9091
594	SJ5	0.9089
595	0MK	0.9089
596	DBH	0.9085
597	FUL	0.9084
598	GAL	0.9083
599	H76	0.9082
600	34V	0.9081
601	32O	0.9080
602	BNF	0.9079
603	SRT	0.9079
604	3F0	0.9077
605	LEU	0.9076
606	ROR	0.9075
607	XX2	0.9074
608	FUC	0.9073
609	JBK	0.9072
610	PAE	0.9072
611	LYL	0.9071
612	M2H	0.9070
613	JIF	0.9070
614	3HL	0.9068
615	MET	0.9068
616	EGD	0.9068
617	CWM	0.9068
618	DMV	0.9067
619	PAF	0.9067
620	3M0	0.9065
621	PRA	0.9063
622	9TY	0.9062
623	BU4	0.9062
624	ARB	0.9060
625	1DW	0.9060
626	FLA	0.9060
627	3HA	0.9059
628	35C	0.9057
629	IZC	0.9057
630	N4B	0.9056
631	DUB	0.9056
632	3MH	0.9055
633	DHB	0.9055
634	7MH	0.9054
635	DMI	0.9053
636	LDP	0.9052
637	SNE	0.9051
638	64K	0.9051
639	3Z7	0.9050
640	NCM	0.9050
641	TLA	0.9045
642	3V4	0.9045
643	PKU	0.9045
644	82I	0.9044
645	AC5	0.9042
646	KMT	0.9040
647	ICF	0.9039
648	1AC	0.9038
649	2ZX	0.9035
650	2D0	0.9033
651	MED	0.9032
652	NNO	0.9032
653	XUL	0.9032
654	5AN	0.9032
655	BAL	0.9031
656	192	0.9030
657	DTI	0.9027
658	3OH	0.9027
659	3DO	0.9025
660	INO	0.9025
661	WDL	0.9024
662	P9P	0.9023
663	CP	0.9022
664	2CQ	0.9021
665	AX2	0.9021
666	ITU	0.9020
667	BMD	0.9019
668	3AY	0.9019
669	150	0.9017
670	RBL	0.9016
671	PG3	0.9015
672	9TW	0.9015
673	13X	0.9014
674	45C	0.9013
675	EHM	0.9012
676	5NU	0.9012
677	GLL	0.9012
678	4ZC	0.9010
679	FUF	0.9010
680	URP	0.9008
681	4A3	0.9006
682	5ZE	0.9005
683	2HO	0.9005
684	ORO	0.9004
685	GLY ALA	0.9002
686	93K	0.9001
687	ABE	0.9000
688	LRH	0.9000
689	JYD	0.8998
690	MTG	0.8997
691	IHG	0.8997
692	94N	0.8993
693	T9G	0.8992
694	3HM	0.8992
695	JB5	0.8992
696	FHB	0.8992
697	1SQ	0.8990
698	R9S	0.8989
699	MYJ	0.8989
700	T6C	0.8987
701	URQ	0.8987
702	1WG	0.8987
703	3HR	0.8986
704	2HA	0.8986
705	MSN	0.8984
706	ARA	0.8982
707	IOM	0.8981
708	R8S	0.8976
709	ADZ	0.8976
710	264	0.8975
711	ES1	0.8974
712	MR1	0.8973
713	3ZS	0.8973
714	XQ0	0.8972
715	SPV	0.8971
716	1NP	0.8971
717	DOR	0.8968
718	3SL	0.8968
719	FJO	0.8968
720	RM1	0.8967
721	JPZ	0.8967
722	DTT	0.8966
723	JBH	0.8966
724	JLZ	0.8966
725	O72	0.8965
726	1LQ	0.8965
727	MEU	0.8965
728	3ID	0.8963
729	COU	0.8962
730	FBV	0.8962
731	5Q0	0.8961
732	5IQ	0.8961
733	N5J	0.8960
734	1LM	0.8960
735	DHS	0.8958
736	A8C	0.8957
737	5CU	0.8957
738	FCA	0.8957
739	SR1	0.8956
740	F4Z	0.8956
741	HQY	0.8956
742	7MU	0.8955
743	SLP	0.8955
744	069	0.8955
745	4YS	0.8955
746	5SG	0.8955
747	24W	0.8955
748	KPL	0.8954
749	DCL	0.8954
750	MUC	0.8954
751	ETX	0.8954
752	BR8	0.8954
753	BUQ	0.8953
754	6F0	0.8953
755	GLU	0.8953
756	7B4	0.8951
757	FA0	0.8950
758	SYG	0.8950
759	I2M	0.8949
760	03V	0.8949
761	XLS	0.8947
762	67N	0.8944
763	ERH	0.8943
764	ES5	0.8943
765	4P5	0.8942
766	6M1	0.8942
767	TBP	0.8941
768	DHK	0.8938
769	5WV	0.8936
770	M1A	0.8935
771	J9T	0.8930
772	4JT	0.8930
773	CLW	0.8928
774	4FS	0.8925
775	XIY	0.8924
776	2AQ	0.8923
777	TC7	0.8923
778	GRE	0.8923
779	ET2	0.8922
780	CMS	0.8919
781	CHB	0.8916
782	I3A	0.8916
783	2ZV	0.8916
784	5RG	0.8915
785	ARW	0.8914
786	DOB	0.8914
787	45L	0.8913
788	GOO	0.8913
789	4SD	0.8913
790	H95	0.8910
791	OXC	0.8910
792	1P7	0.8908
793	XRG	0.8908
794	G3F	0.8907
795	42J	0.8905
796	QSB	0.8904
797	MMU	0.8902
798	BZ3	0.8898
799	IPU	0.8897
800	K2T	0.8895
801	4XH	0.8895
802	ES2	0.8894
803	1P8	0.8894
804	VGD	0.8893
805	5OB	0.8892
806	XCZ	0.8891
807	G6D	0.8891
808	OXM	0.8888
809	PZM	0.8887
810	4M0	0.8886
811	GLA	0.8886
812	IHB	0.8886
813	EV0	0.8885
814	HDH	0.8885
815	MSF	0.8885
816	AHB	0.8884
817	BHA	0.8883
818	5B1	0.8883
819	1DV	0.8883
820	5VM	0.8882
821	1M2	0.8882
822	9DG	0.8882
823	GAF	0.8881
824	TAR	0.8880
825	7HQ	0.8880
826	7W4	0.8878
827	6CS	0.8877
828	OXL	0.8876
829	23B	0.8874
830	BGC	0.8874
831	BUB	0.8873
832	TCZ	0.8873
833	KKN	0.8873
834	AS3	0.8873
835	36R	0.8872
836	2BG	0.8872
837	OCH	0.8870
838	2HE	0.8869
839	3GR	0.8869
840	BXO	0.8867
841	ES7	0.8867
842	OHP	0.8866
843	HH8	0.8866
844	GTQ	0.8866
845	FB1	0.8866
846	HH5	0.8866
847	OTR	0.8861
848	FBB	0.8861
849	H42	0.8861
850	25W	0.8861
851	MTD	0.8860
852	GXL	0.8859
853	AW5	0.8858
854	AZA	0.8858
855	2FG	0.8857
856	KP6	0.8854
857	BAE	0.8854
858	QMP	0.8854
859	TB6	0.8853
860	LZM	0.8851
861	GUN	0.8851
862	PAV	0.8851
863	PYR	0.8849
864	2A9	0.8847
865	ISN	0.8846
866	54G	0.8845
867	PGA	0.8844
868	X6X	0.8844
869	6LW	0.8840
870	D1X	0.8840
871	IPB	0.8839
872	FBW	0.8835
873	JFD	0.8835
874	DMD	0.8834
875	D2P	0.8832
876	QWN	0.8832
877	SX1	0.8831
878	F9Y	0.8831
879	S0H	0.8831
880	4HM	0.8830
881	GCS	0.8829
882	42A	0.8826
883	6GU	0.8825
884	YTB	0.8825
885	9TZ	0.8825
886	8S0	0.8823
887	12M	0.8822
888	EUG	0.8821
889	4M4	0.8821
890	RHU	0.8821
891	ICN	0.8816
892	5M0	0.8816
893	GOJ	0.8815
894	GIV	0.8815
895	CFP	0.8815
896	GIO	0.8814
897	CHT	0.8813
898	173	0.8811
899	RMN	0.8810
900	EQT	0.8810
901	SOE	0.8810
902	MSE	0.8809
903	2H5	0.8808
904	BDP	0.8807
905	2AL	0.8806
906	K34	0.8806
907	51R	0.8804
908	DX4	0.8804
909	ODV	0.8802
910	F0J	0.8801
911	6AP	0.8798
912	XAN	0.8796
913	GRO	0.8795
914	QXW	0.8794
915	B2J	0.8793
916	FSG	0.8793
917	34D	0.8793
918	SYC	0.8790
919	GUA	0.8790
920	IGA	0.8789
921	5MK	0.8788
922	A2F	0.8788
923	AFR	0.8787
924	TMH	0.8787
925	GG6	0.8786
926	1GN	0.8786
927	FCR	0.8786
928	MFB	0.8785
929	GZL	0.8781
930	CN0	0.8781
931	0CU	0.8780
932	V55	0.8779
933	1XN	0.8779
934	LGC	0.8779
935	RNS	0.8778
936	141	0.8776
937	290	0.8775
938	YIO	0.8775
939	SEJ	0.8774
940	AKG	0.8774
941	9RW	0.8773
942	SAN	0.8772
943	AZG	0.8771
944	6HQ	0.8771
945	FCN	0.8770
946	2AS	0.8770
947	3BB	0.8766
948	YH7	0.8765
949	PEP	0.8764
950	OXD	0.8764
951	ASC	0.8763
952	OPE	0.8762
953	GLF	0.8762
954	PUT	0.8762
955	FA1	0.8762
956	ZXD	0.8761
957	0PY	0.8761
958	PHZ	0.8758
959	FCB	0.8758
960	149	0.8758
961	FRU	0.8757
962	TSU	0.8754
963	4ZA	0.8752
964	DCD	0.8752
965	FPK	0.8750
966	1XM	0.8748
967	BNZ	0.8747
968	KTA	0.8747
969	IPZ	0.8747
970	8WT	0.8747
971	3DM	0.8746
972	DS0	0.8746
973	PE9	0.8746
974	13P	0.8744
975	ADK	0.8744
976	B20	0.8742
977	HGY	0.8742
978	SMN	0.8741
979	4XV	0.8739
980	1SA	0.8738
981	DIE	0.8737
982	BTL	0.8736
983	G3P	0.8734
984	BDF	0.8734
985	PA1	0.8734
986	BOA	0.8729
987	3AL	0.8727
988	HV2	0.8724
989	SKM	0.8724
990	2TQ	0.8723
991	RM4	0.8723
992	AAS	0.8722
993	R8V	0.8722
994	XQG	0.8721
995	HSO	0.8718
996	7VD	0.8718
997	SC2	0.8717
998	LAC	0.8715
999	KBG	0.8714
1000	8X3	0.8714
1001	B53	0.8711
1002	AUD	0.8710
1003	P1R	0.8709
1004	4WL	0.8708
1005	TYL	0.8705
1006	TIU	0.8705
1007	4J8	0.8705
1008	BCP	0.8704
1009	DE5	0.8701
1010	IV2	0.8701
1011	3HP	0.8697
1012	AEG	0.8695
1013	GDE	0.8695
1014	263	0.8694
1015	449	0.8694
1016	ALA	0.8694
1017	FBS	0.8692
1018	GLN	0.8692
1019	2PG	0.8689
1020	NAK	0.8689
1021	4HP	0.8687
1022	M1E	0.8684
1023	8OZ	0.8681
1024	RAM	0.8680
1025	ALL	0.8678
1026	ETM	0.8677
1027	ISU	0.8675
1028	PYM	0.8673
1029	SEP	0.8670
1030	XXR	0.8670
1031	MBG	0.8667
1032	2OP	0.8665
1033	4AA	0.8662
1034	SWA	0.8658
1035	A7W	0.8655
1036	5QX	0.8654
1037	F5B	0.8654
1038	FDK	0.8654
1039	BUO	0.8654
1040	BMA	0.8653
1041	K5W	0.8652
1042	DAL	0.8652
1043	LYS	0.8649
1044	KJH	0.8647
1045	5JQ	0.8647
1046	PTO	0.8647
1047	0V5	0.8645
1048	PBA	0.8643
1049	4NM	0.8643
1050	CWS	0.8640
1051	COM	0.8639
1052	POA	0.8636
1053	A09	0.8636
1054	0P6	0.8634
1055	2EC	0.8630
1056	HPS	0.8629
1057	URC	0.8624
1058	DSS	0.8624
1059	BTY	0.8622
1060	OVP	0.8619
1061	5JL	0.8619
1062	HC4	0.8617
1063	MRW	0.8613
1064	3PF	0.8613
1065	EKZ	0.8612
1066	TTL	0.8611
1067	XAZ	0.8610
1068	QSH	0.8610
1069	3MA	0.8610
1070	7W1	0.8609
1071	9X6	0.8609
1072	E5X	0.8608
1073	TAU	0.8607
1074	KUF	0.8603
1075	SYV	0.8602
1076	12Q	0.8601
1077	8K2	0.8600
1078	3MB	0.8598
1079	HJP	0.8596
1080	FOT	0.8595
1081	NF3	0.8593
1082	MZB	0.8592
1083	SVJ	0.8590
1084	OVM	0.8583
1085	PMF	0.8578
1086	IJZ	0.8576
1087	IFP	0.8569
1088	C2U	0.8566
1089	OW4	0.8564
1090	B55	0.8563
1091	FGZ	0.8562
1092	3RK	0.8553
1093	5RN	0.8553
1094	HQT	0.8552
1095	3Z8	0.8550
1096	3FH	0.8550
1097	2HQ	0.8548
1098	UNC	0.8548
1099	8TX	0.8547
1100	PAH	0.8545
1101	ANN	0.8538
1102	DIU	0.8537
1103	QBK	0.8530
1104	FBT	0.8529

Similar Binding Sites (Proteins are less than 50% similar to leader)

Pocket No.: 1; Query (leader) PDB : 1ZOA; Ligand: 140; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.

This union binding pocket(no: 1) in the query (biounit: 1zoa.bio1) has 36 residues
No:	Leader PDB	Ligand	Sequence Similarity

Pocket No.: 2; Query (leader) PDB : 1ZOA; Ligand: 140; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.

This union binding pocket(no: 2) in the query (biounit: 1zoa.bio2) has 37 residues
No:	Leader PDB	Ligand	Sequence Similarity

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