Receptor
PDB id Resolution Class Description Source Keywords
4HI0 2.35 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF HELICOBACTER PYLORI UREASE ACCESSORY PR UREF/H/G COMPLEX HELICOBACTER PYLORI METALLOCHAPERONE METAL BINDING PROTEIN UREASE CYTOSOL
Ref.: STRUCTURE OF UREG/UREF/UREH COMPLEX REVEALS HOW URE ACCESSORY PROTEINS FACILITATE MATURATION OF HELICOB PYLORI UREASE. PLOS BIOL. V. 11 01678 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP E:201;
F:201;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4HI0 2.35 Å EC: 2.-.-.- CRYSTAL STRUCTURE OF HELICOBACTER PYLORI UREASE ACCESSORY PR UREF/H/G COMPLEX HELICOBACTER PYLORI METALLOCHAPERONE METAL BINDING PROTEIN UREASE CYTOSOL
Ref.: STRUCTURE OF UREG/UREF/UREH COMPLEX REVEALS HOW URE ACCESSORY PROTEINS FACILITATE MATURATION OF HELICOB PYLORI UREASE. PLOS BIOL. V. 11 01678 2013
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 236 families.
1 4HI0 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 211 families.
1 4HI0 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 166 families.
1 4HI0 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4HI0; Ligand: GDP; Similar sites found: 573
This union binding pocket(no: 1) in the query (biounit: 4hi0.bio1) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5FTB ANP 0.00003735 0.5179 2.51256
2 5FHD ADP ALF 0.0001637 0.46776 2.51256
3 1AZT GSP 0.00000003542 0.64222 2.64151
4 5IRR GSP 0.000008975 0.51133 2.64151
5 5GVR LMR 0.0000797 0.53551 2.99145
6 3BER AMP 0.004244 0.43179 3.01508
7 1RYH GNP 0.000001578 0.52217 3.51759
8 3DEF GDP 0.000002644 0.52119 3.51759
9 1NJF ADP 0.00005587 0.48083 3.6
10 1NJF AGS 0.0001022 0.47865 3.6
11 4XFR CIT 0.02611 0.40249 3.74707
12 2BME GNP 0.0000008579 0.57465 3.76344
13 3UIE ANP 0.000003392 0.50343 4.0201
14 1ZIN AP5 0.0001737 0.49492 4.0201
15 2ZTS ADP 0.0005774 0.44887 4.0201
16 2NCD ADP 0.0000004981 0.65042 4.15094
17 5WRJ A3P 0.001031 0.43969 4.15094
18 1KAO GDP 0.0000002766 0.56647 4.19162
19 1O3Y GTP 0.00000005743 0.61988 4.21687
20 4R2I ANP 0.0006455 0.48355 4.28571
21 1YZN GNP 0.000001482 0.5667 4.32432
22 1XMV ADP 0.00007271 0.4422 4.33071
23 2QQ0 ANP 0.001679 0.44136 4.34783
24 2QQ0 THM 0.001449 0.44136 4.34783
25 2QQ0 TMP 0.001765 0.4404 4.34783
26 4PPF FLC 0.000001263 0.64683 4.52261
27 1WF3 GNP 0.000001222 0.57033 4.52261
28 1JI0 ATP 0.00001422 0.56811 4.52261
29 2XTN GTP 0.000001389 0.56069 4.52261
30 3TMK T5A 0.0004236 0.46331 4.52261
31 5WRI A3P 0.00101 0.43633 4.52261
32 2ZR9 DTP 0.00008751 0.43182 4.52261
33 4CVN ADP 0.000003357 0.46442 4.71204
34 2BCG GDP 0.0000005453 0.56411 4.72441
35 3SBD GNP 0.00004623 0.46163 4.81283
36 1SVK ALF GDP 0.00000003767 0.64343 4.90566
37 1Y3A GDP 0.0000000199 0.63957 4.90566
38 1BH2 GSP 0.00000008368 0.62583 4.90566
39 5MZN ADP 0.0001681 0.51338 4.90566
40 3IIJ ADP 0.000001267 0.50184 5
41 1RE0 GDP 0.000000005018 0.57606 5.02513
42 5G41 AP5 0.0001142 0.50931 5.02513
43 1SVM ATP 0.0008195 0.47171 5.02513
44 5VGR GDP 0.0005063 0.45586 5.02513
45 4P32 ADP 0.00087 0.43909 5.02513
46 1S8F GDP 0.0000004846 0.59012 5.08475
47 1XTQ GDP 0.000003304 0.54458 5.08475
48 4ZG4 VO4 ADP 0.0002285 0.46587 5.11811
49 2ZPA ADP 0.0002254 0.45522 5.11811
50 2B8W ALF 5GP 0.001146 0.43773 5.11811
51 4KFU ACP 0.000004195 0.44852 5.18868
52 1E96 GTP 0.00003561 0.50468 5.20833
53 1M7G AV2 0.0000005893 0.50232 5.21327
54 1M7G ADX 0.00008821 0.49662 5.21327
55 1M7G ADP 0.0001717 0.48052 5.21327
56 2FJU GSP 0.00001962 0.50671 5.28302
57 1IWE IMP 0.001023 0.49686 5.28302
58 3FKQ ATP 0.00008792 0.46577 5.28302
59 1GWN GTP 0.000004639 0.5332 5.36585
60 1MH1 GNP 0.000009639 0.47857 5.37634
61 4ZNL BEF ADP 0.0000682 0.51209 5.51181
62 5XDR ADP 0.0003657 0.47761 5.51181
63 2FAH GDP 0.00008483 0.46117 5.51181
64 2XT3 ADP 0.0000004417 0.45939 5.51181
65 4YMU ATP 0.000009835 0.5676 5.52764
66 3CNL GNP 0.00000003479 0.54959 5.52764
67 2QZ4 ADP 0.000002284 0.51051 5.52764
68 3FWY ADP 0.00001392 0.49787 5.52764
69 3FB4 AP5 0.0002841 0.48518 5.52764
70 1K6M AGS 0.0002574 0.46366 5.52764
71 2BEK ATP 0.001799 0.44634 5.52764
72 5X40 ACP 0.0007722 0.44324 5.52764
73 2PZE ATP 0.000003259 0.43278 5.52764
74 1R0X ATP 0.00006705 0.43201 5.52764
75 1P3D ANP 0.004478 0.40696 5.52764
76 1GQY ACP 0.002812 0.40251 5.52764
77 5MVR ADP 0.000004523 0.48155 5.55556
78 1ION ADP 0.000007943 0.48832 5.76132
79 1ZD9 GDP 0.00000003397 0.63155 5.85106
80 1EK0 GNP 0.000003102 0.55051 5.88235
81 4PX9 ADP 0.00005044 0.53232 5.90551
82 2EW1 GNP 0.000001147 0.56425 5.97015
83 1M7B GTP 0.000004375 0.53427 5.97826
84 5CK5 GDP 0.000000000721 0.60123 6.03015
85 4R98 GNH 0.000000007123 0.58624 6.03015
86 1WDT GTP 0.000002099 0.55422 6.03015
87 2CE7 ADP 0.000005566 0.49507 6.03015
88 3W5J GDP 0.0000002147 0.47831 6.03015
89 3BOS CDP 0.00001174 0.46282 6.03015
90 2C77 GNP 0.0000001398 0.59751 6.03774
91 2C78 GNP 0.000000314 0.58554 6.03774
92 4PFO ADP 0.0002144 0.47096 6.03774
93 3R7F CP 0.02477 0.40547 6.03774
94 3NKV GNP 0.0000007829 0.57637 6.28571
95 1XKV ATP 0.00001799 0.4785 6.29921
96 3Q9L ATP 0.0002932 0.44488 6.29921
97 1P72 ADP 0.0008765 0.45391 6.41509
98 2VF7 ADP 0.00007525 0.44371 6.41509
99 1TU3 GNP 0.000001533 0.56375 6.43275
100 4QM7 GTP 0.000005355 0.48011 6.43275
101 1R2Q GNP 0.000000342 0.60934 6.47059
102 5M04 GDP 0.0000000139 0.55738 6.53266
103 3ZQ6 ADP ALF 0.00000596 0.54043 6.53266
104 1V8K ANP 0.00001447 0.45981 6.53266
105 2IS6 ADP 0.00001808 0.45754 6.53266
106 2VVG ADP 0.0000002663 0.44913 6.53266
107 3B5J 12D 0.00001682 0.44074 6.53266
108 2J59 GTP 0.0000000818 0.61331 6.54762
109 1SVI GDP 0.0000007262 0.51298 6.66667
110 4PJ3 ANP 0.0001699 0.48202 6.69291
111 1RRC ADP 0.0000005912 0.45743 6.69291
112 1Z0F GDP 0.000000007157 0.59768 6.70391
113 1FP6 ADP 0.00003927 0.47223 6.79245
114 5I34 GDP 0.00002133 0.46808 6.79245
115 2OZE AGS 0.0003639 0.447 6.79245
116 1XP8 AGS 0.0001336 0.4162 6.79245
117 3BFX A3P 0.002444 0.41325 6.79245
118 2A5J GDP 0.00000005097 0.57611 6.80628
119 1Z0A GDP 0.00000001679 0.59367 6.89655
120 4LHW GNP 0.000001243 0.56769 6.89655
121 3SFV GDP 0.0000003402 0.58117 7.03518
122 4P4T GDP 0.0000002942 0.57509 7.03518
123 4H1V GNP 0.0000008625 0.54934 7.03518
124 4D81 ADP 0.000009048 0.53948 7.03518
125 4MKF AP5 0.0002699 0.48741 7.03518
126 1YTM ATP 0.0001177 0.47382 7.03518
127 2F3R G5P 0.003635 0.42643 7.03518
128 5LB3 ADP 0.00004741 0.53365 7.08661
129 4V0K GDP 0.00000003894 0.62997 7.10059
130 1H65 GDP 0.000009153 0.52324 7.16981
131 1G41 ADP 0.00003535 0.46714 7.16981
132 3TBK ANP 0.0002169 0.41113 7.16981
133 5H56 ADP 0.00003888 0.51062 7.17949
134 5H56 TYD 0.00003888 0.51062 7.17949
135 3T5G GDP 0.0000003413 0.54644 7.18232
136 3GJ8 GDP 0.00000005156 0.65964 7.23982
137 1DS6 GDP 0.000000837 0.51444 7.29167
138 3E5H GNP 0.000005527 0.53966 7.30337
139 1NN5 ANP 0.000727 0.45607 7.44186
140 2WJG GDP 0.00000000121 0.74888 7.44681
141 3TNF GNP 0.0000005662 0.58717 7.47126
142 2FH5 GTP 0.0000002521 0.58668 7.47664
143 1G4U GDP 0.000009818 0.51355 7.48031
144 1OS1 ATP 0.0002974 0.47005 7.48031
145 1OS1 PYR 0.0003238 0.47005 7.48031
146 4HSE ADP 0.00001697 0.46681 7.48031
147 3P4X ADP 0.00001324 0.45786 7.48031
148 2CHG ANP 0.00003719 0.48109 7.52212
149 4RD0 GDP 0.0000003593 0.58305 7.53769
150 4M9Q GNP 0.0000004372 0.57943 7.53769
151 3EC1 GDP 0.000002204 0.50899 7.53769
152 3IO3 ADP 0.0000135 0.5057 7.53769
153 1QF5 GDP 0.0003925 0.48861 7.53769
154 2WKQ GTP 0.00003184 0.48173 7.53769
155 1G6O ADP 0.00003153 0.46448 7.53769
156 1F9V ADP 0.000001646 0.45767 7.53769
157 1QF5 RPL 0.00706 0.45762 7.53769
158 2IXE ATP 0.0005158 0.44875 7.53769
159 1T5C ADP 0.0000004781 0.44188 7.53769
160 4IHQ ADP 0.00004427 0.43644 7.53769
161 4IDN GNP 0.001053 0.42614 7.53769
162 2RCN GDP 0.000000001229 0.60795 7.54717
163 5K5Z ANP 0.0004215 0.42931 7.54717
164 2W2X GSP 0.000003865 0.53655 7.56757
165 4WEI GLC GAL 0.005603 0.44643 7.58123
166 1GXU 2HP 0.0003902 0.48544 7.69231
167 1QF9 C5P 0.0002948 0.4806 7.73196
168 1Z2A GDP 0.00000004902 0.59018 7.7381
169 2PEZ DAT 0.000007242 0.54648 7.82123
170 2PEZ GGZ 0.000007242 0.44455 7.82123
171 5GJC ATP 0.000102 0.51027 7.87402
172 2ZE7 DST 0.001209 0.44014 7.90514
173 2ZE7 AMP 0.003985 0.41604 7.90514
174 2XTZ GSP 0.0000004383 0.58726 8.0402
175 3CPJ GDP 0.0000003869 0.55273 8.0402
176 1Z6T ADP 0.00009832 0.46269 8.0402
177 1W5T ANP 0.0002863 0.45749 8.0402
178 1W5T ADP 0.0003991 0.43986 8.0402
179 1NST A3P 0.003053 0.40391 8.0402
180 1F6B GDP 0.00000002736 0.5743 8.08081
181 1KK1 GNP 0.000000001341 0.59349 8.26772
182 1D2E GDP 0.0000001587 0.56913 8.26772
183 1OXV ANP 0.00001226 0.45194 8.26772
184 2GK6 ADP 0.0001718 0.41294 8.26772
185 1G3M PCQ 0.01211 0.40977 8.26772
186 4KBF AMP 0.0006886 0.40267 8.26772
187 4KAX GTP 0.0000001235 0.60279 8.28402
188 3H86 AP5 0.0006879 0.46137 8.33333
189 4ITR GDP 0.000006831 0.51955 8.37696
190 1A4R GDP 0.000009435 0.51378 8.37696
191 2NGR GDP 0.000001994 0.51126 8.37696
192 1A4R GNH 0.00001032 0.50608 8.37696
193 1GRN GDP 0.00001078 0.50537 8.37696
194 2D7C GTP 0.0000004834 0.58542 8.38323
195 5KSP GDP 0.000003776 0.5715 8.42105
196 2WMO GTP 0.000004406 0.50575 8.42105
197 2WJH GDP 0.00000003044 0.57352 8.43373
198 2WJH FLC 0.0000006384 0.53361 8.43373
199 3ZS9 ADP ALF 0.00001557 0.52231 8.47458
200 2WOJ ADP ALF 0.00001891 0.46249 8.47458
201 5GOE GDP 0.00000002419 0.6651 8.54271
202 4PC3 GDP 0.00000003753 0.64696 8.54271
203 1ZCB GDP 0.00000001907 0.64614 8.54271
204 3CX8 GSP 0.00000008246 0.62611 8.54271
205 2BVN GNP 0.0000001556 0.56804 8.54271
206 4P3Y GDP 0.000000008797 0.56635 8.54271
207 5JBQ GDP 0.00000002624 0.56622 8.54271
208 3U6B GDP 0.00000001172 0.56582 8.54271
209 3U6K GDP 0.0000000307 0.56571 8.54271
210 4G5G GDP 0.00000002787 0.56521 8.54271
211 1D8T GDP 0.00000002836 0.56456 8.54271
212 2J0V GDP 0.00000155 0.51342 8.54271
213 4MKG AP5 0.000312 0.48333 8.54271
214 1BG2 ADP 0.0000004139 0.44368 8.54271
215 1OE0 TTP 0.001476 0.43638 8.54271
216 2PL3 ADP 0.00009784 0.42812 8.54271
217 2WHX ADP 0.00001781 0.42706 8.54271
218 1LVG ADP 0.00000009295 0.5136 8.58586
219 3N5C GDP 0.000000005842 0.71576 8.64198
220 1IN4 ADP 0.0001058 0.46896 8.66142
221 4JGT PYR 0.02148 0.40632 8.66142
222 4C12 ADP 0.02633 0.40584 8.66142
223 1QHG ATP 0.002175 0.40468 8.66142
224 5KSZ GCP 0.00002657 0.52473 8.67924
225 3B7G ANP 0.0004447 0.42225 8.69565
226 1NRJ GTP 0.00000003769 0.62157 8.7156
227 3PQC GDP 0.00001589 0.48833 8.71795
228 1UJ2 ADP 0.0001246 0.48305 8.73016
229 1UJ2 C5P 0.0001831 0.47578 8.73016
230 1S3G AP5 0.000233 0.48911 8.75576
231 5WDR GNP 0.0000007808 0.57879 8.77193
232 4YC7 GNP 0.00001639 0.51247 8.83978
233 3VX3 ADP 0.00009165 0.47215 8.87097
234 1HE1 GDP 0.00001056 0.51808 8.88889
235 1Z06 GNP 0.0000007537 0.57461 8.99471
236 2ZFI ADP 0.00001548 0.54994 9.01639
237 1GOJ ADP 0.0000002076 0.69035 9.04523
238 3BFV ADP 0.000001864 0.59447 9.04523
239 4AG5 ADP 0.000008098 0.58759 9.04523
240 2A9K GDP 0.0000001434 0.5785 9.04523
241 1FNN ADP 0.00004716 0.48397 9.04523
242 3QXC ATP 0.001166 0.44083 9.04523
243 2Z5F A3P 0.003462 0.41169 9.04523
244 2ZPT A3P 0.02115 0.41039 9.04523
245 4A4Z ANP 0.0009369 0.40711 9.04523
246 2ORV 4TA 0.008182 0.40249 9.04523
247 1X6V ADP 0.0000158 0.52598 9.05512
248 4V03 ADP 0.00001052 0.48301 9.05512
249 1PUJ GNP 0.000000006352 0.62097 9.0566
250 1W0J ADP 0.0001173 0.45261 9.0566
251 1W0J ADP BEF 0.0004418 0.44328 9.0566
252 1Z83 AP5 0.001066 0.45151 9.18367
253 1W4R TTP 0.00299 0.42457 9.23077
254 2JAQ DCP 0.003361 0.41589 9.26829
255 4TTQ ATP 0.00002193 0.46132 9.30233
256 1KK8 BEF ADP 0.0001544 0.45457 9.35252
257 5EP2 AZU 0.006385 0.40042 9.375
258 4TMK T5A 0.00408 0.42548 9.38967
259 5LTJ ADP 0.00008203 0.44227 9.43396
260 1W7J ADP BEF 0.00005812 0.49735 9.44882
261 1SQ5 ADP 0.000003655 0.49501 9.44882
262 5M7P ADP 0.00004542 0.48428 9.44882
263 4QOS ADP 0.0000358 0.46715 9.44882
264 1E2K TMC 0.0007403 0.46622 9.44882
265 3COB ADP 0.0000004008 0.46049 9.44882
266 4FRZ ADP 0.000001513 0.45627 9.44882
267 5HR5 ADP 0.0003892 0.43848 9.44882
268 3GJ0 GDP 0.0000000335 0.67901 9.54774
269 5UWP GNP 0.0000005657 0.58719 9.54774
270 5UWI GNP 0.0000005026 0.58711 9.54774
271 4HAT GNP 0.0000006004 0.58606 9.54774
272 5UWT GNP 0.0000005455 0.58556 9.54774
273 5UWR GNP 0.0000005513 0.58536 9.54774
274 5BXQ GDP 0.00000002175 0.5797 9.54774
275 3GJX GTP 0.0000008611 0.57694 9.54774
276 3CH5 GDP 0.00000005195 0.56629 9.54774
277 5UWH GNP 0.0000004246 0.52327 9.54774
278 5DIF GNP 0.0000005039 0.52097 9.54774
279 5UWU GNP 0.0000005316 0.52018 9.54774
280 5UWO GNP 0.0000005401 0.51978 9.54774
281 5UWW GNP 0.0000005575 0.51945 9.54774
282 5UWJ GNP 0.0000005563 0.51944 9.54774
283 5UWQ GNP 0.0000005743 0.51898 9.54774
284 5DHF GNP 0.0000005736 0.51897 9.54774
285 5UWS GNP 0.0000005781 0.51001 9.54774
286 5DI9 GNP 0.0000006824 0.50769 9.54774
287 1JJ7 ADP 0.0000003454 0.44491 9.54774
288 1U0J ADP 0.0003017 0.41198 9.54774
289 4OI4 ATP 0.001765 0.42786 9.56522
290 1GOT GDP 0.00000001265 0.64487 9.58904
291 1B7T ADP 0.00008127 0.45017 9.61539
292 2ZEJ GDP 0.0000005419 0.58568 9.78261
293 5J1J ANP 0.00002809 0.48131 9.81132
294 3KTA AP5 0.0001449 0.4473 9.82659
295 1F5N GNP 0.0003319 0.42 9.84252
296 4OHY ANP 0.001679 0.40643 9.84252
297 1XEX ATP 0.0006094 0.45133 9.88372
298 1G16 GDP 0.0000007943 0.5684 10
299 1Z08 GNP 0.000001723 0.55668 10
300 4ZI2 GNP 0.000002066 0.5371 10
301 4J0Q GDP 0.000000002394 0.58644 10.0503
302 1JWY GDP 0.0000001442 0.56893 10.0503
303 5FG3 GDP 0.00000001671 0.56051 10.0503
304 4XTR ADP 0.00002497 0.50778 10.0503
305 4XTR ATP 0.00001685 0.48964 10.0503
306 4XVU ATP 0.00002006 0.48684 10.0503
307 1JJV ATP 0.0000009289 0.47037 10.0503
308 1JWY ADP 0.00003758 0.45452 10.0503
309 3FYH ADP 0.0005207 0.45246 10.0503
310 3EWA ANP 0.00002744 0.44896 10.0503
311 3QKT ANP 0.000791 0.44465 10.0503
312 2GDJ ANP 0.00005261 0.44114 10.0503
313 4GOJ GNP 0.000001105 0.5623 10.0529
314 5BQ5 ADP BEF 0.000008331 0.54798 10.0529
315 3TKL GTP 0.0000005264 0.58132 10.1887
316 1L2T ATP 0.0006112 0.44947 10.2128
317 5I0H ADP BEF 0.0003077 0.45617 10.2362
318 1P9B GDP 0.0002439 0.44815 10.2362
319 3FVQ ATP 0.001211 0.431 10.2362
320 1UAD GNP 0.000000533 0.58359 10.2857
321 2HT6 GDP 0.00000000254 0.58379 10.3448
322 2CJW GDP 0.0000000003991 0.62403 10.4167
323 1XX6 ADP 0.000486 0.40221 10.4712
324 4QRH 0O2 0.002976 0.41447 10.4762
325 1FZQ GDP 0.00000007761 0.54576 10.4972
326 2ODE ALF GDP 0.00000006317 0.63119 10.5528
327 3B9Q MLI 0.00001117 0.57341 10.5528
328 3VMF GTP 0.000003143 0.55027 10.5528
329 3WXM GTP 0.000005777 0.53883 10.5528
330 5N69 ADP 0.00004737 0.50704 10.5528
331 1YQT ADP 0.00000324 0.44891 10.5528
332 1G6H ADP 0.0000005473 0.44187 10.5528
333 1IBR GNP 0.0000008152 0.57798 10.566
334 5IRN ADP 0.00002153 0.48142 10.566
335 2FNA ADP 0.0001923 0.45623 10.566
336 1G7C 5GP 0.0000004281 0.52557 10.6383
337 1U8Z GDP 0.00000006041 0.61894 10.7143
338 1WA5 GTP 0.0000003801 0.60131 10.7955
339 2QEN ADP 0.00005998 0.47205 10.9434
340 1VHT BA3 0.00002995 0.47235 11.0092
341 3DKP ADP 0.00009963 0.43674 11.0204
342 3KJI ADP 0.000007646 0.50201 11.0236
343 1CR1 TTP 0.0002308 0.46145 11.0236
344 1VKJ A3P 0.006274 0.40075 11.0236
345 4ZKD GDP 0.000003671 0.54957 11.0553
346 5EE5 GTP 0.0000002383 0.59064 11.1111
347 4DID GDP 0.00000153 0.51493 11.1842
348 1G3Q ADP 0.000001761 0.50381 11.3924
349 3WYF GTP 0.0000004625 0.59101 11.4155
350 3M1I GTP 0.0000004633 0.58864 11.4155
351 3DOE GTP 0.0000001559 0.60133 11.4583
352 1OFH ADP 0.00004587 0.46323 11.4943
353 4XGU ADP 0.00006802 0.49433 11.5578
354 3ZFD ANP 0.00002952 0.46659 11.5578
355 1DAK DPU 0.001865 0.45009 11.5578
356 4U00 ADP 0.000000592 0.44274 11.5578
357 2GMV UN8 0.001154 0.40075 11.5578
358 1UPT GTP 0.0000001162 0.6039 11.6667
359 1KSH GDP 0.0000005912 0.57103 11.828
360 1YVD GNP 0.000001302 0.56682 11.8343
361 4NE2 SH2 0.00005513 0.51346 11.976
362 4NE2 ADP 0.00004728 0.51346 11.976
363 4WOP CTP 0.0006271 0.44309 12
364 2WIC GNP 0.0000000006107 0.7507 12.0603
365 2OFW ADX 0.000005121 0.56317 12.0603
366 1CS4 GSP 0.0000001879 0.52666 12.0603
367 2C9O ADP 0.00002047 0.50594 12.0603
368 4BFW ZVW 0.0007571 0.46577 12.0603
369 3GJ4 GDP 0.00000004783 0.55806 12.1212
370 3AB3 GDP 0.0000002201 0.58917 12.1951
371 2GJ8 ALF GDP 0.000002708 0.49715 12.2093
372 4U5X GNP 0.000008435 0.51551 12.3596
373 2A5F GTP 0.00000001108 0.65346 12.4352
374 1TQ4 GDP 0.00000002653 0.62802 12.5628
375 4BAS GNP 0.00000004174 0.62282 12.5628
376 2QG6 NMN 0.0002075 0.4752 12.5628
377 2Y65 ADP 0.000001179 0.44749 12.5628
378 3H4S ADP 0.0000005354 0.45496 12.5926
379 4YS0 ADP 0.001085 0.44125 12.5984
380 3Q72 GNP 0.000000004351 0.5827 12.6506
381 1IHU ADP 0.000009103 0.52575 12.8302
382 1IHU AF3 0.00000854 0.52452 12.8302
383 1NY5 ADP 0.0001262 0.4597 12.8302
384 3EZ2 ADP 0.00005664 0.43172 12.8302
385 4JLV ADP 0.00003134 0.4386 12.9921
386 2F9L GDP 0.0000002293 0.59415 13.0653
387 4TMZ GSP 0.0000007785 0.57144 13.0653
388 4NCN GTP 0.000001008 0.56664 13.0653
389 2IYL GDP 0.000002978 0.49459 13.0653
390 1UKZ ADP 0.0003825 0.47138 13.0653
391 3A4M ADP 0.0000004524 0.48825 13.0769
392 1KY3 GDP 0.0000001371 0.56898 13.1868
393 4IOK ADP 0.001363 0.43949 13.2075
394 4IOK XPO 0.001537 0.43223 13.2075
395 4R43 GDP 0.00003233 0.53444 13.3858
396 4WZA ADP 0.0001207 0.52119 13.3858
397 4WZA ACP 0.0001207 0.52119 13.3858
398 3WYA GDP 0.0000000004906 0.62358 13.5678
399 2G77 GDP 0.00000006721 0.59166 13.5678
400 3WY9 GDP 0.00000001398 0.56524 13.5678
401 4LYA ATP 0.0000388 0.52367 13.5678
402 2RGX AP5 0.0001432 0.50124 13.5678
403 2FSH ANP 0.000247 0.4153 13.5678
404 3QBT GNP 0.0000008529 0.52297 13.5714
405 3AQ4 GDP 0.000000001703 0.61782 13.587
406 3RAB GNP 0.000002257 0.55648 13.6095
407 1OIV GDP 0.0000004747 0.58576 13.6126
408 1KO8 6PG 0.00005469 0.48198 13.7143
409 5H67 ATP 0.002053 0.44218 13.75
410 1MR3 G3D 0.00000000262 0.61149 13.8122
411 1ZJ6 G3D 0.000000001864 0.61683 13.9037
412 3A1S GDP 0.000005433 0.49926 13.9535
413 1D2N ANP 0.000501 0.44722 13.9623
414 2Y8E GNP 0.000001084 0.57026 13.9665
415 3RWO GDP 0.0000001543 0.60687 14.0541
416 1DAR GDP 0.000000002621 0.59542 14.0704
417 5L3R GCP 0.000002578 0.5142 14.0704
418 4RZ3 ADP 0.00006816 0.47139 14.0704
419 1GP2 GDP 0.000000009699 0.61806 14.0845
420 1F2U ATP 0.001162 0.44088 14.094
421 1B0U ATP 0.000354 0.43281 14.1221
422 1ZC3 GNP 0.0000001022 0.61717 14.2857
423 2W83 GTP 0.00000006738 0.61691 14.2857
424 5SZH GNP 0.0000005461 0.58554 14.3791
425 2CK3 ADP 0.0004966 0.45144 14.3836
426 2V7Q ATP 0.00008566 0.45016 14.3836
427 2CK3 ANP 0.0005244 0.44027 14.3836
428 2V7Q ADP 0.00009931 0.4322 14.3836
429 4YLG GDP 0.00000001199 0.62095 14.4509
430 4NON GDP 0.0000001845 0.60844 14.5669
431 2XAU ADP 0.0003733 0.42577 14.5669
432 3DZD ADP 0.0000172 0.48905 14.5729
433 5IFS ADP 0.00001159 0.48547 14.5729
434 2W58 ADP 0.000001064 0.4354 14.5729
435 2FFQ GSP 0.000001362 0.56829 14.6199
436 1Y63 ADP 0.0000006732 0.5076 14.6739
437 5UQW GDP 0.0000003831 0.58725 14.8148
438 4DSU GDP 0.0000006187 0.58318 14.8148
439 5KDO GDP 0.000000006772 0.6531 14.8649
440 1ZUI SKM 0.0001355 0.49443 14.881
441 2JLR ANP 0.0003948 0.43113 14.9606
442 5TAR GDP 0.00000003761 0.64692 15.1351
443 5TB5 GDP 0.00000002336 0.5899 15.1351
444 2X77 GDP 0.0000001567 0.54825 15.3439
445 3NHB ADP 0.000008347 0.43479 15.3543
446 1MKY GDP 0.000000001995 0.60513 15.5779
447 1SKQ GDP 0.0000000005803 0.60384 15.5779
448 4B47 GDP 0.0000000035 0.57901 15.5779
449 2EFE GNH 0.0000001505 0.57034 15.5779
450 4TQK NAG 0.02301 0.40617 15.5779
451 1NF3 GNP 0.00002948 0.46863 15.625
452 1FQK GDP 0.00000004999 0.62246 15.748
453 1TAD GDP 0.0000001073 0.6211 15.748
454 1TAD ALF 0.0000001073 0.52739 15.748
455 3PCR GTP 0.0000002352 0.56427 15.8491
456 1D5C GDP 0.0000002772 0.56703 16.0494
457 3LRE ADP 0.000000304 0.44747 16.0804
458 1YZG GDP 0.000000002455 0.61239 16.2011
459 5JCZ GDP 0.0000005149 0.58057 16.2011
460 2BIF ANP 0.0006278 0.46178 16.2264
461 2BIF SIN 0.001112 0.46148 16.2264
462 5XCO GDP 0.0000001092 0.57417 16.3743
463 4LX0 BEF GDP 0.000001015 0.57383 16.3842
464 5O2T GSP 0.0000004182 0.52481 16.568
465 3T34 GDP 0.000001115 0.53758 16.5829
466 4E03 ADP 0.00005309 0.45667 16.5829
467 3RLF ANP 0.0006057 0.44775 16.5829
468 2AWN ADP 0.0000003167 0.43106 16.5829
469 2OM2 GDP 0.000000006826 0.65295 16.6667
470 4C4P GNP 0.0000009598 0.57489 16.763
471 5UFQ GNP 0.000000312 0.53717 16.8675
472 3REF GDP 0.00001327 0.51637 17.0103
473 4IEE AGS 0.0003555 0.49017 17.3228
474 1R4A GNP 0.00000002288 0.6399 17.5758
475 2Q2Y ADP 0.0009427 0.46143 17.5879
476 2Q2Y MKR 0.0008883 0.46143 17.5879
477 2D7D ADP 0.0002736 0.42056 17.5879
478 3GJ5 GDP 0.00000006014 0.56378 17.6471
479 4KVA GTP 0.00001169 0.41302 17.7165
480 1OIX GDP 0.0000003386 0.59211 17.801
481 1VG8 GNP 0.0000004199 0.5905 17.8744
482 1VG0 GDP 0.00000009302 0.57614 17.8744
483 4YDS ATP 0.000005341 0.58981 17.9825
484 5KUT GDP 0.0000001149 0.55707 17.9894
485 4BQS ADP 0.000002159 0.59137 18.1818
486 3GJ3 GDP 0.0000000512 0.5564 18.1818
487 3GJ7 GDP 0.00000003859 0.56057 18.3673
488 1G8S MET 0.01515 0.41758 18.593
489 1Z0K GTP 0.000001017 0.56647 18.8406
490 1M2O GNP 0.0000002989 0.59445 18.9474
491 2KIN ADP 0.000000573 0.43922 19
492 2CBZ ATP 0.0000007467 0.65917 19.0955
493 1LFD GNP 0.0000008925 0.57391 19.1617
494 5TSH ANP 0.000003462 0.48117 19.2913
495 5TSH ADP 0.00000779 0.44216 19.2913
496 2QN6 GDP 0.000000006646 0.57587 19.3548
497 5JCP GDP ALF 0.000003562 0.55086 19.598
498 2DPY ADP 0.0001006 0.52475 19.598
499 1I4D GDP 0.000001577 0.49919 19.598
500 5E95 GDP 0.00000003979 0.63698 19.6429
501 2C5L GTP 0.0000003613 0.59334 19.6532
502 1X1R GDP 0.0000007522 0.57949 19.6629
503 3WYG GTP 0.0000002973 0.59939 19.7368
504 3X1Z GNP 0.0000008849 0.50537 19.7605
505 1WQ1 GDP 0.0000002547 0.5922 19.8795
506 3KUD GDP 0.0000003507 0.58062 19.8795
507 3DDC GNP 0.000001221 0.57035 19.8795
508 1CLU DBG 0.0000003596 0.43784 19.8795
509 4K81 GTP 0.00000007723 0.62495 19.883
510 1VG1 GDP 0.00000001512 0.58366 20
511 1VG9 GDP 0.00000002629 0.57619 20
512 2VB6 ADP BEF 0.0001656 0.47185 20.1342
513 1OW3 GDP 0.000004296 0.52127 20.2073
514 3BC1 GNP 0.000001379 0.56574 20.339
515 1GUA GNP 0.0000008195 0.51479 20.3593
516 2UZI GTP 0.0000003709 0.5904 20.4819
517 1NVU GTP 0.00000109 0.5725 20.4819
518 1OYY AGS 0.001253 0.40204 20.603
519 1S9D GDP 0.000000001356 0.73433 20.6897
520 3T12 GDP ALF 0.00000001456 0.64228 20.7071
521 3T1O GDP 0.0000000009913 0.63738 20.7071
522 2GCN GDP 0.000008605 0.52438 20.8955
523 2GCO GNP 0.000004434 0.52016 20.8955
524 4HDO GNP 0.0000009484 0.57512 20.9581
525 4HDQ GNP 0.000001315 0.56895 20.9581
526 3LXR GDP 0.000001831 0.57835 21.0811
527 4D0N GDP 0.0000002283 0.53534 21.0811
528 5HPY GDP 0.000002815 0.52844 21.0811
529 5J1S ATP 0.0003033 0.4347 21.1382
530 1KMQ GNP 0.00001043 0.52322 21.1957
531 1FQJ GDP 0.00000004934 0.6227 21.4286
532 4KVG GTP 0.0000004027 0.58885 21.4286
533 2HV8 GTP 0.00000104 0.57104 21.5116
534 4XOI GTP 0.00001239 0.5223 21.6667
535 4D0G GTP 0.0000002811 0.58758 21.7391
536 4XSH GSP 0.000006663 0.53255 21.7877
537 1TX4 ALF GDP 0.0000146 0.49467 22.0339
538 1G7S GDP 0.0000001101 0.64407 22.1106
539 4WZ6 ATP 0.000009829 0.58412 22.1106
540 5DI3 GNP 0.0000002935 0.5715 22.1622
541 4FCW ADP 0.00002761 0.46758 22.6131
542 4DCT GDP 0.0000004073 0.53581 23.622
543 4LJ9 ACP 0.00006478 0.44544 24.1206
544 1J2J GTP 0.0000001263 0.57455 24.4444
545 1RJ9 GCP 0.00002288 0.53908 24.6231
546 2C04 GCP 0.00001976 0.51802 24.6231
547 3Q85 GNP 0.0000000225 0.56739 24.8521
548 5L3V GDP 0.000001852 0.57812 25.1256
549 1YRB GDP 0.0000000668 0.58202 25.1908
550 1CXZ GSP 0.000004028 0.5384 25.5814
551 5L3S GNP 0.000004744 0.50474 25.6281
552 5L3W GDP 0.00002789 0.47572 25.6281
553 5L3S G 0.01732 0.41442 25.6281
554 3QF7 ANP 0.0004363 0.44301 26
555 3DC4 ADP 0.000005261 0.45023 27.6382
556 2QTV GNP 0.0000002757 0.5934 28.5714
557 3ZIA ADP 0.00003722 0.47265 28.5714
558 3ZIA ATP 0.00003177 0.45812 28.5714
559 3MJH GTP 0.000001232 0.56785 29.4118
560 5IRC GDP 0.00001011 0.49299 30.3483
561 5HCN GCP 0.0000001316 0.64041 31.1558
562 1R6B ADP 0.00002813 0.46425 31.6583
563 1Z0J GTP 0.0000008654 0.57685 32.2034
564 3MD0 GDP 0.000000008881 0.57038 33.1658
565 3TK1 GDP 0.00000009363 0.52757 33.6683
566 4DKX GDP 0.00000001659 0.6938 34.6734
567 4LC1 GDP 0.0000004815 0.62294 35.1759
568 1HTW ADP 0.000003148 0.49888 35.443
569 1YZQ GNP 0.000001668 0.56447 40.5882
570 3E70 GDP 0.000002303 0.50612 41.206
571 4LPS GDP 0.00000002201 0.58097 42.7136
572 2HCJ GDP 0.00000001803 0.56305 43.2432
573 1NVV GNP 0.000001098 0.57236 49.3976
Pocket No.: 2; Query (leader) PDB : 4HI0; Ligand: GDP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4hi0.bio1) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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