-->
Receptor
PDB id Resolution Class Description Source Keywords
4IGH 1.3 Å EC: 1.3.5.2 HIGH RESOLUTION CRYSTAL STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE BOUND WITH 4-QUINOLINE CARBOXYLIC ACID ANALOG HOMO SAPIENS ANTI-VIRAL QUINOLINE-4-CARBOXYLIC ACID REDOX DEHYDROGENASMEMBRANE OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
Ref.: SAR BASED OPTIMIZATION OF A 4-QUINOLINE CARBOXYLIC ANALOG WITH POTENT ANTI-VIRAL ACTIVITY. ACS MED.CHEM.LETT. V. 4 517 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FMN A:501;
Valid;
none;
submit data
456.344 C17 H21 N4 O9 P Cc1cc...
ZWI A:504;
Invalid;
none;
submit data
307.492 C15 H33 N O3 S CCCCC...
GOL A:506;
A:505;
Invalid;
Invalid;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
1EA A:503;
Valid;
none;
ic50 = 1 nM
415.456 C26 H22 F N O3 Cc1cc...
ORO A:502;
Valid;
none;
submit data
156.096 C5 H4 N2 O4 C1=C(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4IGH 1.3 Å EC: 1.3.5.2 HIGH RESOLUTION CRYSTAL STRUCTURE OF HUMAN DIHYDROOROTATE DEHYDROGENASE BOUND WITH 4-QUINOLINE CARBOXYLIC ACID ANALOG HOMO SAPIENS ANTI-VIRAL QUINOLINE-4-CARBOXYLIC ACID REDOX DEHYDROGENASMEMBRANE OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX
Ref.: SAR BASED OPTIMIZATION OF A 4-QUINOLINE CARBOXYLIC ANALOG WITH POTENT ANTI-VIRAL ACTIVITY. ACS MED.CHEM.LETT. V. 4 517 2013
Members (39)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 5ZF9 ic50 = 6 nM 9BR C23 H31 Cl O3 Cc1c(c(c(c....
2 3KVL ic50 = 5.5 uM 7Z5 C17 H19 N3 O3 CCC(=O)Nc1....
3 3F1Q ic50 = 0.117 uM BCE C17 H14 N2 O2 C/C(=C(C#N....
4 2FPT ic50 = 33 nM ILB C20 H14 F5 N O4 c1cc(cc(c1....
5 3G0X ic50 = 0.053 uM MD7 C19 H16 N2 O2 c1ccc(cc1)....
6 2PRL ic50 = 81 nM R2C C20 H17 N O4 COc1ccc(c(....
7 6CJF ic50 = 0.0262 uM F54 C23 H16 Cl F N2 O2 Cc1ccc(c(n....
8 3FJ6 ic50 = 0.022 uM CIH C17 H12 Cl2 N2 O2 C/C(=C(C#N....
9 4OQV ic50 = 1.6 uM 2V6 C14 H7 F8 N5 Cc1cc(n2c(....
10 2B0M - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
11 5MVC ic50 = 0.016 uM Y9B C15 H7 F4 N3 O2 S c1ccc(cc1)....
12 3U2O ic50 = 110 nM 03U C20 H17 F N2 O4 CC/C(=C(C#....
13 3KVM ic50 = 0.5 uM 951 C18 H13 Cl N2 O3 c1ccc(c(c1....
14 1D3H - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
15 2FQI ic50 = 7 nM ILH C20 H10 F7 N O4 c1cc(cc(c1....
16 5ZFA ic50 = 21.5 nM 9BU C22 H29 Cl O5 Cc1c(c(c(c....
17 3ZWS ic50 = 0.051 uM AVQ C13 H10 Cl2 N4 O S Cc1cc(n2c(....
18 5K9D - FNR C17 H23 N4 O9 P Cc1cc2c(cc....
19 5ZFB - 9BX C23 H29 Cl O5 Cc1c(c(c(c....
20 5MVD ic50 = 0.041 uM U91 C18 H13 F4 N3 O2 Cc1c(c(nn1....
21 5ZF8 ic50 = 6.4 nM 9BO C21 H27 Cl O5 Cc1c(c(c(c....
22 5ZF7 ic50 = 63.9 nM CHW C19 H25 Cl O4 Cc1c(c(c(c....
23 2FPY ic50 = 2 nM ILF C19 H10 F5 N O4 S c1cc(cc(c1....
24 5K9C ic50 = 0.56 uM MLJ C21 H21 F3 N2 O3 c1ccc2c(c1....
25 3G0U ic50 = 0.2 uM MDY C18 H15 Cl N2 O3 C/C(=C(C#N....
26 4IGH ic50 = 1 nM 1EA C26 H22 F N O3 Cc1cc(c(cc....
27 6FMD ic50 = 0.0012 uM DUH C20 H11 F4 N3 O2 c1ccc(cc1)....
28 3FJL ic50 = 0.13 uM CJH C19 H18 N2 O3 CCOc1cccc(....
29 2PRH ic50 = 15 nM 238 C23 H15 Cl F N O2 Cc1c(c2cc(....
30 2FPV ic50 = 44 nM ILC C19 H14 F N O4 S COc1cccc(c....
31 3ZWT ic50 = 0.013 uM KFZ C14 H12 Cl2 N4 O S CCc1cc(n2c....
32 3KVK ic50 = 0.7 uM 6X1 C14 H10 Cl2 N2 O3 c1ccc(c(c1....
33 1D3G - BRE C23 H16 F N O2 Cc1c(c2cc(....
34 2BXV ic50 = 280 nM 3FT C20 H15 F4 N O4 c1cc(cc(c1....
35 3KVJ ic50 = 0.1 uM 1X5 C18 H19 N3 O3 CN(Cc1cccn....
36 5MUT ic50 = 0.045 uM HYT C16 H10 F4 N4 O2 Cn1nc(c(n1....
37 2WV8 ic50 = 0.21 uM VGN C21 H17 N O3 CC(=O)Nc1c....
38 5ZF4 ic50 = 4.2 nM 9BL C19 H23 Cl O5 Cc1c(c(c(c....
39 6ET4 ic50 = 11 nM SDV C21 H17 F N4 O2 c1ccc2c(c1....
70% Homology Family (42)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 5ZF9 ic50 = 6 nM 9BR C23 H31 Cl O3 Cc1c(c(c(c....
2 3KVL ic50 = 5.5 uM 7Z5 C17 H19 N3 O3 CCC(=O)Nc1....
3 3F1Q ic50 = 0.117 uM BCE C17 H14 N2 O2 C/C(=C(C#N....
4 2FPT ic50 = 33 nM ILB C20 H14 F5 N O4 c1cc(cc(c1....
5 3G0X ic50 = 0.053 uM MD7 C19 H16 N2 O2 c1ccc(cc1)....
6 2PRL ic50 = 81 nM R2C C20 H17 N O4 COc1ccc(c(....
7 6CJF ic50 = 0.0262 uM F54 C23 H16 Cl F N2 O2 Cc1ccc(c(n....
8 3FJ6 ic50 = 0.022 uM CIH C17 H12 Cl2 N2 O2 C/C(=C(C#N....
9 4OQV ic50 = 1.6 uM 2V6 C14 H7 F8 N5 Cc1cc(n2c(....
10 2B0M - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
11 5MVC ic50 = 0.016 uM Y9B C15 H7 F4 N3 O2 S c1ccc(cc1)....
12 3U2O ic50 = 110 nM 03U C20 H17 F N2 O4 CC/C(=C(C#....
13 3KVM ic50 = 0.5 uM 951 C18 H13 Cl N2 O3 c1ccc(c(c1....
14 1D3H - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
15 2FQI ic50 = 7 nM ILH C20 H10 F7 N O4 c1cc(cc(c1....
16 5ZFA ic50 = 21.5 nM 9BU C22 H29 Cl O5 Cc1c(c(c(c....
17 3ZWS ic50 = 0.051 uM AVQ C13 H10 Cl2 N4 O S Cc1cc(n2c(....
18 5K9D - FNR C17 H23 N4 O9 P Cc1cc2c(cc....
19 5ZFB - 9BX C23 H29 Cl O5 Cc1c(c(c(c....
20 5MVD ic50 = 0.041 uM U91 C18 H13 F4 N3 O2 Cc1c(c(nn1....
21 5ZF8 ic50 = 6.4 nM 9BO C21 H27 Cl O5 Cc1c(c(c(c....
22 5ZF7 ic50 = 63.9 nM CHW C19 H25 Cl O4 Cc1c(c(c(c....
23 2FPY ic50 = 2 nM ILF C19 H10 F5 N O4 S c1cc(cc(c1....
24 5K9C ic50 = 0.56 uM MLJ C21 H21 F3 N2 O3 c1ccc2c(c1....
25 3G0U ic50 = 0.2 uM MDY C18 H15 Cl N2 O3 C/C(=C(C#N....
26 4IGH ic50 = 1 nM 1EA C26 H22 F N O3 Cc1cc(c(cc....
27 6FMD ic50 = 0.0012 uM DUH C20 H11 F4 N3 O2 c1ccc(cc1)....
28 3FJL ic50 = 0.13 uM CJH C19 H18 N2 O3 CCOc1cccc(....
29 2PRH ic50 = 15 nM 238 C23 H15 Cl F N O2 Cc1c(c2cc(....
30 2FPV ic50 = 44 nM ILC C19 H14 F N O4 S COc1cccc(c....
31 3ZWT ic50 = 0.013 uM KFZ C14 H12 Cl2 N4 O S CCc1cc(n2c....
32 3KVK ic50 = 0.7 uM 6X1 C14 H10 Cl2 N2 O3 c1ccc(c(c1....
33 1D3G - BRE C23 H16 F N O2 Cc1c(c2cc(....
34 2BXV ic50 = 280 nM 3FT C20 H15 F4 N O4 c1cc(cc(c1....
35 3KVJ ic50 = 0.1 uM 1X5 C18 H19 N3 O3 CN(Cc1cccn....
36 5MUT ic50 = 0.045 uM HYT C16 H10 F4 N4 O2 Cn1nc(c(n1....
37 2WV8 ic50 = 0.21 uM VGN C21 H17 N O3 CC(=O)Nc1c....
38 5ZF4 ic50 = 4.2 nM 9BL C19 H23 Cl O5 Cc1c(c(c(c....
39 6ET4 ic50 = 11 nM SDV C21 H17 F N4 O2 c1ccc2c(c1....
40 1UUO ic50 = 6 nM BRF C23 H15 F2 N O2 Cc1c(c2cc(....
41 4ORI ic50 = 0.088 uM 2V6 C14 H7 F8 N5 Cc1cc(n2c(....
42 1UUM ic50 = 698 nM AFI C22 H19 Cl O3 c1ccc2c(c1....
50% Homology Family (57)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1TV5 Ki ~ 1000 nM A26 C12 H9 F3 N2 O2 C/C(=C(C#N....
2 3I65 ic50 = 0.047 uM JZ8 C16 H15 N5 Cc1cc([n+]....
3 6I55 ic50 = 12 uM DZB C17 H15 N3 O2 S c1ccc(cc1)....
4 6GJG - ORO C5 H4 N2 O4 C1=C(NC(=O....
5 4RX0 - D65 C14 H12 F7 N5 S Cc1cc(n2c(....
6 5DEL ic50 = 16 nM D59 C14 H10 Cl2 N2 O3 Cc1c(cccc1....
7 5TBO - 78Z C14 H11 F5 N6 Cc1cc(n2c(....
8 4CQ8 ic50 = 0.08 uM JBW C17 H14 N4 O S Cc1nc2c(cc....
9 3I68 ic50 = 0.056 uM J4Z C20 H15 N5 Cc1cc(n2c(....
10 4ORM ic50 = 0.0018 uM 2V6 C14 H7 F8 N5 Cc1cc(n2c(....
11 6E0B - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
12 3O8A ic50 = 0.022 uM O8A C17 H14 F3 N3 O2 S Cc1nc2cc(c....
13 5FI8 ic50 = 0.0046 uM 5Y5 C18 H18 Br F2 N5 Cc1cc(n2c(....
14 6I4B ic50 = 2.8 uM E2N C13 H11 F3 N2 O4 Cn1c(c(c(n....
15 3I6R ic50 = 0.28 uM J5Z C13 H10 F3 N5 Cc1cc(n2c(....
16 5ZF9 ic50 = 6 nM 9BR C23 H31 Cl O3 Cc1c(c(c(c....
17 3KVL ic50 = 5.5 uM 7Z5 C17 H19 N3 O3 CCC(=O)Nc1....
18 3F1Q ic50 = 0.117 uM BCE C17 H14 N2 O2 C/C(=C(C#N....
19 2FPT ic50 = 33 nM ILB C20 H14 F5 N O4 c1cc(cc(c1....
20 3G0X ic50 = 0.053 uM MD7 C19 H16 N2 O2 c1ccc(cc1)....
21 2PRL ic50 = 81 nM R2C C20 H17 N O4 COc1ccc(c(....
22 6CJF ic50 = 0.0262 uM F54 C23 H16 Cl F N2 O2 Cc1ccc(c(n....
23 3FJ6 ic50 = 0.022 uM CIH C17 H12 Cl2 N2 O2 C/C(=C(C#N....
24 4OQV ic50 = 1.6 uM 2V6 C14 H7 F8 N5 Cc1cc(n2c(....
25 2B0M - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
26 5MVC ic50 = 0.016 uM Y9B C15 H7 F4 N3 O2 S c1ccc(cc1)....
27 3U2O ic50 = 110 nM 03U C20 H17 F N2 O4 CC/C(=C(C#....
28 3KVM ic50 = 0.5 uM 951 C18 H13 Cl N2 O3 c1ccc(c(c1....
29 1D3H - FMN C17 H21 N4 O9 P Cc1cc2c(cc....
30 2FQI ic50 = 7 nM ILH C20 H10 F7 N O4 c1cc(cc(c1....
31 5ZFA ic50 = 21.5 nM 9BU C22 H29 Cl O5 Cc1c(c(c(c....
32 3ZWS ic50 = 0.051 uM AVQ C13 H10 Cl2 N4 O S Cc1cc(n2c(....
33 5K9D - FNR C17 H23 N4 O9 P Cc1cc2c(cc....
34 5ZFB - 9BX C23 H29 Cl O5 Cc1c(c(c(c....
35 5MVD ic50 = 0.041 uM U91 C18 H13 F4 N3 O2 Cc1c(c(nn1....
36 5ZF8 ic50 = 6.4 nM 9BO C21 H27 Cl O5 Cc1c(c(c(c....
37 5ZF7 ic50 = 63.9 nM CHW C19 H25 Cl O4 Cc1c(c(c(c....
38 2FPY ic50 = 2 nM ILF C19 H10 F5 N O4 S c1cc(cc(c1....
39 5K9C ic50 = 0.56 uM MLJ C21 H21 F3 N2 O3 c1ccc2c(c1....
40 3G0U ic50 = 0.2 uM MDY C18 H15 Cl N2 O3 C/C(=C(C#N....
41 4IGH ic50 = 1 nM 1EA C26 H22 F N O3 Cc1cc(c(cc....
42 6FMD ic50 = 0.0012 uM DUH C20 H11 F4 N3 O2 c1ccc(cc1)....
43 3FJL ic50 = 0.13 uM CJH C19 H18 N2 O3 CCOc1cccc(....
44 2PRH ic50 = 15 nM 238 C23 H15 Cl F N O2 Cc1c(c2cc(....
45 2FPV ic50 = 44 nM ILC C19 H14 F N O4 S COc1cccc(c....
46 3ZWT ic50 = 0.013 uM KFZ C14 H12 Cl2 N4 O S CCc1cc(n2c....
47 3KVK ic50 = 0.7 uM 6X1 C14 H10 Cl2 N2 O3 c1ccc(c(c1....
48 1D3G - BRE C23 H16 F N O2 Cc1c(c2cc(....
49 2BXV ic50 = 280 nM 3FT C20 H15 F4 N O4 c1cc(cc(c1....
50 3KVJ ic50 = 0.1 uM 1X5 C18 H19 N3 O3 CN(Cc1cccn....
51 5MUT ic50 = 0.045 uM HYT C16 H10 F4 N4 O2 Cn1nc(c(n1....
52 2WV8 ic50 = 0.21 uM VGN C21 H17 N O3 CC(=O)Nc1c....
53 5ZF4 ic50 = 4.2 nM 9BL C19 H23 Cl O5 Cc1c(c(c(c....
54 6ET4 ic50 = 11 nM SDV C21 H17 F N4 O2 c1ccc2c(c1....
55 1UUO ic50 = 6 nM BRF C23 H15 F2 N O2 Cc1c(c2cc(....
56 4ORI ic50 = 0.088 uM 2V6 C14 H7 F8 N5 Cc1cc(n2c(....
57 1UUM ic50 = 698 nM AFI C22 H19 Cl O3 c1ccc2c(c1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FMN; Similar ligands found: 15
No: Ligand ECFP6 Tc MDL keys Tc
1 FMN 1 1
2 RBF 0.75641 0.876712
3 RS3 0.571429 0.831169
4 FAD 0.543307 0.876543
5 FAS 0.543307 0.876543
6 FAE 0.539062 0.865854
7 LFN 0.475 0.643836
8 C3F 0.473684 0.74359
9 CF4 0.463918 0.734177
10 FAY 0.446043 0.864198
11 FNR 0.444444 0.909091
12 RFL 0.442857 0.845238
13 4LS 0.411215 0.875
14 1VY 0.406593 0.769231
15 DLZ 0.404494 0.782051
Ligand no: 2; Ligand: 1EA; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 1EA 1 1
Ligand no: 3; Ligand: ORO; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 ORO 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4IGH; Ligand: 1EA; Similar sites found with APoc: 410
This union binding pocket(no: 1) in the query (biounit: 4igh.bio1) has 88 residues
No: Leader PDB Ligand Sequence Similarity
1 1IS3 LAT None
2 4WG0 CHD None
3 4JIQ FMN 1.34409
4 4JIQ 1L5 1.34409
5 5MTE BB2 1.45985
6 2WD7 VGD 1.49254
7 5OSW DIU 1.6129
8 2GUD BMA 1.63934
9 2GUD MAN 1.63934
10 2HYR BGC GLC 1.63934
11 4LH7 NMN 1.85759
12 5NM7 GLY 1.8797
13 5E70 RCD 1.88172
14 4MRP GSH 1.88172
15 2GOU FMN 1.88172
16 2B56 U5P 1.88172
17 4M26 AKG 1.92308
18 4Q0P 0MK 1.92308
19 4K10 NI9 1.9337
20 5Z21 OXM 1.95531
21 2FJK 13P 1.96721
22 1QDS PGA 1.99203
23 3T03 3T0 2.11268
24 5YRF GLC GLC 2.11268
25 5A7V MAN 2.15054
26 5A7V BMA 2.15054
27 4CW5 FMN 2.20264
28 1A78 TDG 2.23881
29 4TX6 38B 2.25806
30 5K52 OCD 2.26415
31 3HQ9 OXL 2.31884
32 3GLC R5P 2.37288
33 2R14 FMN 2.38727
34 2R14 TXD 2.38727
35 1ICP FMN 2.41935
36 1OYB FMN 2.41935
37 5U97 PIT 2.41935
38 1OYB HBA 2.41935
39 6C4A PYR 2.41935
40 2UZ1 TPP 2.41935
41 3UIM ANP 2.45399
42 2GJ3 FAD 2.5
43 5N5U 7N8 2.54777
44 6FOF LAT 2.55102
45 3WBZ ATP 2.58303
46 3O01 DXC 2.5974
47 5H2U 1N1 2.62172
48 3KP6 SAL 2.64901
49 2UW1 GVM 2.66272
50 3ATY FMN 2.68817
51 2O1V ADP 2.68817
52 3WV6 GAL BGC 2.7027
53 3WV6 GAL GLC 2.7027
54 5M0T AKG 2.72109
55 4BI7 PGA 2.72374
56 2ZFU SAH 2.7907
57 4A3U FMN 2.7933
58 1SW0 PGA 2.82258
59 3GYT DL4 2.86885
60 1C1L GAL BGC 2.91971
61 2HHP FLC 2.95699
62 3TII ANP 2.95699
63 1GNI OLA 2.95699
64 4XNV BUR 2.95699
65 4UZI IMD 2.95699
66 5AZC PGT 3
67 4ELG 52J 3.01205
68 5KAU RHQ 3.0303
69 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 3.06122
70 6BR9 6OU 3.06407
71 3FRQ ERY 3.07692
72 4O08 PO6 3.11526
73 3TL1 JRO 3.14465
74 6BR8 PGV 3.1746
75 6BR8 6OU 3.1746
76 5G5W R8C 3.21429
77 4QNW FMN 3.22581
78 6BFG FMN 3.22581
79 4QO5 NAG 3.22581
80 1US2 XYP XYP XYP XYP 3.22581
81 1P4C FMN 3.22581
82 4OKD GLC GLC GLC 3.22581
83 5Z5I XYP 3.22581
84 3T1A 5MA 3.22581
85 1Z48 FMN 3.25444
86 1Z44 FMN 3.25444
87 1Z42 FMN 3.25444
88 1Z41 FMN 3.25444
89 2BLE 5GP 3.26975
90 3W54 RNB 3.34347
91 5VJE GOS 3.35196
92 4B16 NAG 3.38346
93 4UXL 5P8 3.41615
94 2C6Q IMP 3.4188
95 2BHW NEX 3.44828
96 2Q3O FMN 3.49462
97 1DJN FMN 3.49462
98 5ABH YWN 3.49462
99 3KRU FMN 3.49854
100 5HCV 60R 3.50195
101 4CL6 7SB 3.50877
102 3BQD DAY 3.52941
103 4P6X HCY 3.52941
104 5CSS G3P 3.53982
105 3X01 AMP 3.56234
106 2BJ4 OHT 3.57143
107 3N9R TD3 3.58306
108 4N02 FNR 3.64146
109 5O1I 9GH 3.65297
110 6D28 NEC 3.663
111 4C1W SLT 3.7234
112 1DTL BEP 3.72671
113 1H5R THM 3.75427
114 1H5T TYD 3.75427
115 1H5S TMP 3.75427
116 4TMC FMN 3.76344
117 2HSA FMN 3.76344
118 4TMC HBA 3.76344
119 4AF0 IMP 3.76344
120 3MTW M3R 3.76344
121 4Z0G 5GP 3.76344
122 1YC4 43P 3.78788
123 2UXI G50 3.80952
124 1S20 TLA 3.82353
125 3G5K BB2 3.82514
126 4GAH 0ET 3.82775
127 1C9K 5GP 3.88889
128 2XN5 FUN 4
129 1QFT HSM 4
130 3HF3 FMN 4.01146
131 5YFT RI2 4.01235
132 6BKA FMN 4.03226
133 5AHN IMP 4.03226
134 5AHM IMP 4.03226
135 1P1M MET 4.03226
136 3UXL CFI 4.03226
137 3G4G D71 4.03226
138 2ZRU FMN 4.07609
139 4KGM ATP 4.08163
140 2FLI DX5 4.09091
141 1S8G DAO 4.13223
142 2H8Z FMN 4.17827
143 2H8Z 8CM 4.17827
144 2HFU MEV 4.21687
145 4GBD MCF 4.30108
146 5V4R MGT 4.32099
147 5TVI MYR 4.34783
148 1LQY BB2 4.34783
149 3SAO NKN 4.375
150 2WPW ACO 4.42478
151 1TUK PGM 4.47761
152 3ZXE PGZ 4.51128
153 3VKC FPQ 4.54545
154 4M5P FMN 4.56989
155 3NB0 G6P 4.56989
156 4KRG SAH 4.56989
157 5GLT BGC GAL NAG GAL 4.57746
158 1Q6O LG6 4.62963
159 4IXH IMP 4.70914
160 5CX6 CDP 4.83871
161 2IDO TMP 4.83871
162 4NAO AKG 4.90798
163 1VYP FMN 4.94506
164 1VYP TNF 4.94506
165 4RC8 STE 4.95496
166 3KC1 2T6 5.04451
167 1PU7 39A 5.04587
168 3NV3 GAL NAG MAN 5.07246
169 5GVH FMN 5.09554
170 3TDC 0EU 5.10753
171 3HOK Q80 5.15021
172 4UA3 COA 5.15464
173 2GJN FMN 5.18293
174 2GJN NIS 5.18293
175 5LX9 OLB 5.21173
176 1R6N 434 5.21327
177 1GVF PGH 5.24476
178 2B4D COA 5.26316
179 4G86 BNT 5.28169
180 4XCP PLM 5.29412
181 4IJP 1EH 5.30726
182 1FX8 BOG 5.33808
183 5X3R 7Y3 5.36585
184 6CQF F97 5.38721
185 5OCS FMN 5.39084
186 6GWR FEW 5.39683
187 1JCM 137 5.40541
188 1SR7 MOF 5.40541
189 3B0P FMN 5.42857
190 3IAE D7K 5.4386
191 5VCV 1N1 5.46624
192 1MJJ HAL 5.47945
193 3E3U NVC 5.58376
194 3M3E GAL A2G NPO 5.59006
195 3WFD AXO 5.6338
196 2Q3R FMN 5.64516
197 2V6A CAP 5.64516
198 1UZD CAP 5.64516
199 2V67 CAP 5.64516
200 2V68 CAP 5.64516
201 1IR2 CAP 5.64516
202 2V63 CAP 5.64516
203 2VDH CAP 5.64516
204 1UZH CAP 5.64516
205 1IR1 CAP 5.64516
206 1TLL FMN 5.64516
207 3GUZ PAF 5.68182
208 3CEV ARG 5.68562
209 3OVR 5SP 5.70175
210 5TCI MLI 5.7971
211 2OEM 1AE 5.81114
212 1OX5 1PR 5.91398
213 1ZFJ IMP 5.91398
214 3P9T TCL 5.93607
215 6H8S FSZ 5.98007
216 3TAO PGH 5.99251
217 2WZM NA7 6.00707
218 3GWN FAD 6.14035
219 6CB2 OLC 6.14334
220 2QCD U5P 6.15385
221 2GJ5 VD3 6.17284
222 2QJY UQ2 6.1828
223 3GAY P6T 6.19195
224 5JPH COA 6.25
225 3L0E G58 6.32411
226 3QH2 3NM 6.33484
227 3EXS 5RP 6.33484
228 2GWH PCI 6.37584
229 4Q9N 0WE 6.37584
230 3GC0 AMP 6.38298
231 5CAE COA 6.38978
232 2F6U CIT 6.41026
233 3B99 U51 6.45161
234 4JEJ 1GP 6.55738
235 2DBX GLU 6.55738
236 2Y88 2ER 6.55738
237 5DG2 GAL GLC 6.66667
238 5EPQ OLA 6.70732
239 5WHU SIA 6.71141
240 1VHN FMN 6.72043
241 1WDD CAP 6.72043
242 2BTM PGA 6.74603
243 2BCG GER 6.79612
244 3W9Z FMN 6.8323
245 3B6C SDN 6.83761
246 2YMZ LAT 6.92308
247 6BVE PGA 6.93878
248 3P13 RIP 6.94444
249 6B21 C9V 6.98925
250 1YYE 196 7.08955
251 5W7B MYR 7.0922
252 5CC2 CKA 7.16981
253 4YMZ 13P 7.17131
254 2Q1H AS4 7.2
255 1S17 GNR 7.22222
256 1PS9 FMN 7.25806
257 6DIO CIT 7.25806
258 6GSG RCO 7.25806
259 3U3U EAH 7.29614
260 6BXL SAM 7.40741
261 1M5W DXP 7.40741
262 4NTK ZSP 7.43802
263 1TF9 PHI 7.74648
264 4JGX PLM 7.75194
265 1OFD AKG 7.7957
266 1OFD FMN 7.7957
267 4RJK TPP 7.7957
268 1U3R 338 7.88382
269 6BFN DL1 7.89474
270 4J24 EST 7.91667
271 4J26 EST 7.91667
272 2YJD YJD 7.91667
273 1OQC FAD 8
274 2CB8 MYA 8.04598
275 5DX3 EST 8.04598
276 5DXG EST 8.04598
277 5WGQ EST 8.04598
278 5WGD EST 8.04598
279 5DXE EST 8.04598
280 5C9J DAO 8.08081
281 3WUD GLC GAL 8.08823
282 4URX HXY 8.10811
283 2QA8 GEN 8.13953
284 5HYR EST 8.13953
285 2QZO KN1 8.13953
286 1SLT NDG GAL 8.20895
287 1W6P NDG GAL 8.20895
288 4MGD 27N 8.23529
289 4MG8 27J 8.23529
290 4TUZ 36J 8.23529
291 4MG7 27H 8.23529
292 4MGB XDH 8.23529
293 4WGF HX2 8.29268
294 4YSX E23 8.33333
295 4TV1 36M 8.36653
296 3UUD EST 8.36653
297 5K53 STE 8.39695
298 3RMK BML 8.43373
299 4NAE 1GP 8.44444
300 1ELW GLY PRO THR ILE GLU GLU VAL ASP 8.47458
301 4XJC TTP 8.47458
302 1UJP CIT 8.48709
303 4R5M NAP 8.60215
304 1ULE GLA GAL NAG 8.66667
305 6A63 LAT 8.69565
306 1BWV CAP 8.69565
307 2Z6I FMN 8.73494
308 2Z6J FMN 8.73494
309 4DOO DAO 8.78049
310 2D6M LBT 8.80503
311 1HE1 GDP 8.88889
312 3CTL S6P 9.09091
313 4UTU LRY 9.17031
314 4UTW RFW 9.17031
315 1AL8 FMN 9.1922
316 1AL8 DHP 9.1922
317 1T0S BML 9.30233
318 3OKI OKI 9.44206
319 1VKF CIT 9.57447
320 5H9Q TD2 9.67742
321 4B1M FRU FRU 9.72973
322 3R9V DXC 9.79021
323 6BMS PLM 9.97067
324 5EYW PGA 10.0402
325 3HYW DCQ 10.2151
326 3RY9 1CA 10.4
327 4DR9 BB2 10.4167
328 2TPS TPS 10.5727
329 2ALG DAO 10.8696
330 2ALG HP6 10.8696
331 5HH0 COA 11
332 2RDT FMN 11.0215
333 2RDT 2RD 11.0215
334 3WG3 A2G GAL NAG FUC 11.236
335 1NU4 MLA 11.3402
336 3FAL REA 11.5702
337 3CR3 ADP 11.5702
338 1J3R 6PG 11.5789
339 4RYV ZEA 11.6129
340 2YPI PGA 11.7409
341 5XQW 8EU 11.8483
342 4EWN 0VR 11.8577
343 1G27 BB1 11.9048
344 1JR8 FAD 11.9658
345 1DKF BMS 12.0172
346 5Y02 HBX 12.1495
347 3TAY MN0 12.2699
348 3H0A 9RA 12.2807
349 4Q4K FMN 12.3249
350 5N9Z CAP 12.3656
351 5OYA CAP 12.3656
352 3WUC GLC GAL 12.4088
353 1WW5 SGA BGC 12.5
354 2YLD CMO 12.5984
355 6BYM HC3 12.8079
356 1RBL CAP 12.844
357 1TB3 FMN 13.0682
358 6DVH FMN 13.172
359 1KBJ FMN 13.172
360 3BW2 FMN 13.2791
361 4XP7 FNR 13.2948
362 5C1M OLC 13.6
363 5NFB 8VT 13.6364
364 2PRG BRL 13.6364
365 3KPE TM3 13.7255
366 6FS0 E4W 13.8365
367 2WOR 2AN 15
368 4NG2 OHN 15.0442
369 4V3I ASP LEU THR ARG PRO 15.1751
370 1TRD PGH 15.2
371 1YRX FMN 15.7025
372 1HBK MYR 15.7303
373 1NF8 BOG 15.942
374 2NLI FMN 16.8478
375 2NLI LAC 16.8478
376 1LYX PGA 17.3387
377 4JLS 3ZE 17.7632
378 3E70 GDP 17.9878
379 3OIX FMN 18.5507
380 4V1F BQ1 18.6047
381 4RRG A3T 19.1489
382 4OGQ 7PH 19.3548
383 4OGQ UMQ 19.3548
384 4XDA ADP 19.4175
385 5MWE TCE 19.7531
386 1KBI PYR 19.8925
387 1KBI FMN 19.8925
388 4RJD TFP 22.7273
389 5W97 CHD 23.2877
390 5ZCO CHD 23.2877
391 5Z84 CHD 23.2877
392 2DYS PGV 23.2877
393 5ZCO PGV 23.2877
394 5Z84 PGV 23.2877
395 5Z84 TGL 23.2877
396 2Y69 CHD 25.6757
397 5OCA 9QZ 30.9524
398 5TBM 79A 32.1739
399 1GTE FMN 35.2151
400 1GTE IUR 35.2151
401 3MJY IJZ 39.0173
402 3MJY FMN 39.0173
403 4WZH FMN 41.2104
404 3C3N FMN 41.6667
405 1OVD ORO 45.6592
406 1OVD FMN 45.6592
407 1EP2 ORO 47.91
408 1EP2 FMN 47.91
409 3BEJ MUF 48
410 1RDT L79 48
Pocket No.: 2; Query (leader) PDB : 4IGH; Ligand: ORO; Similar sites found with APoc: 410
This union binding pocket(no: 2) in the query (biounit: 4igh.bio1) has 88 residues
No: Leader PDB Ligand Sequence Similarity
1 1IS3 LAT None
2 4WG0 CHD None
3 4JIQ FMN 1.34409
4 4JIQ 1L5 1.34409
5 5MTE BB2 1.45985
6 2WD7 VGD 1.49254
7 5OSW DIU 1.6129
8 2GUD BMA 1.63934
9 2GUD MAN 1.63934
10 2HYR BGC GLC 1.63934
11 4LH7 NMN 1.85759
12 5NM7 GLY 1.8797
13 5E70 RCD 1.88172
14 4MRP GSH 1.88172
15 2GOU FMN 1.88172
16 2B56 U5P 1.88172
17 4M26 AKG 1.92308
18 4Q0P 0MK 1.92308
19 4K10 NI9 1.9337
20 5Z21 OXM 1.95531
21 2FJK 13P 1.96721
22 1QDS PGA 1.99203
23 3T03 3T0 2.11268
24 5YRF GLC GLC 2.11268
25 5A7V MAN 2.15054
26 5A7V BMA 2.15054
27 4CW5 FMN 2.20264
28 1A78 TDG 2.23881
29 4TX6 38B 2.25806
30 5K52 OCD 2.26415
31 3HQ9 OXL 2.31884
32 3GLC R5P 2.37288
33 2R14 FMN 2.38727
34 2R14 TXD 2.38727
35 1ICP FMN 2.41935
36 1OYB FMN 2.41935
37 5U97 PIT 2.41935
38 1OYB HBA 2.41935
39 6C4A PYR 2.41935
40 2UZ1 TPP 2.41935
41 3UIM ANP 2.45399
42 2GJ3 FAD 2.5
43 5N5U 7N8 2.54777
44 6FOF LAT 2.55102
45 3WBZ ATP 2.58303
46 3O01 DXC 2.5974
47 5H2U 1N1 2.62172
48 3KP6 SAL 2.64901
49 2UW1 GVM 2.66272
50 3ATY FMN 2.68817
51 2O1V ADP 2.68817
52 3WV6 GAL BGC 2.7027
53 3WV6 GAL GLC 2.7027
54 5M0T AKG 2.72109
55 4BI7 PGA 2.72374
56 2ZFU SAH 2.7907
57 4A3U FMN 2.7933
58 1SW0 PGA 2.82258
59 3GYT DL4 2.86885
60 1C1L GAL BGC 2.91971
61 2HHP FLC 2.95699
62 3TII ANP 2.95699
63 1GNI OLA 2.95699
64 4XNV BUR 2.95699
65 4UZI IMD 2.95699
66 5AZC PGT 3
67 4ELG 52J 3.01205
68 5KAU RHQ 3.0303
69 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 3.06122
70 6BR9 6OU 3.06407
71 3FRQ ERY 3.07692
72 4O08 PO6 3.11526
73 3TL1 JRO 3.14465
74 6BR8 PGV 3.1746
75 6BR8 6OU 3.1746
76 5G5W R8C 3.21429
77 4QNW FMN 3.22581
78 6BFG FMN 3.22581
79 4QO5 NAG 3.22581
80 1US2 XYP XYP XYP XYP 3.22581
81 1P4C FMN 3.22581
82 4OKD GLC GLC GLC 3.22581
83 5Z5I XYP 3.22581
84 3T1A 5MA 3.22581
85 1Z48 FMN 3.25444
86 1Z44 FMN 3.25444
87 1Z42 FMN 3.25444
88 1Z41 FMN 3.25444
89 2BLE 5GP 3.26975
90 3W54 RNB 3.34347
91 5VJE GOS 3.35196
92 4B16 NAG 3.38346
93 4UXL 5P8 3.41615
94 2C6Q IMP 3.4188
95 2BHW NEX 3.44828
96 2Q3O FMN 3.49462
97 1DJN FMN 3.49462
98 5ABH YWN 3.49462
99 3KRU FMN 3.49854
100 5HCV 60R 3.50195
101 4CL6 7SB 3.50877
102 3BQD DAY 3.52941
103 4P6X HCY 3.52941
104 5CSS G3P 3.53982
105 3X01 AMP 3.56234
106 2BJ4 OHT 3.57143
107 3N9R TD3 3.58306
108 4N02 FNR 3.64146
109 5O1I 9GH 3.65297
110 6D28 NEC 3.663
111 4C1W SLT 3.7234
112 1DTL BEP 3.72671
113 1H5R THM 3.75427
114 1H5T TYD 3.75427
115 1H5S TMP 3.75427
116 4TMC FMN 3.76344
117 2HSA FMN 3.76344
118 4TMC HBA 3.76344
119 4AF0 IMP 3.76344
120 3MTW M3R 3.76344
121 4Z0G 5GP 3.76344
122 1YC4 43P 3.78788
123 2UXI G50 3.80952
124 1S20 TLA 3.82353
125 3G5K BB2 3.82514
126 4GAH 0ET 3.82775
127 1C9K 5GP 3.88889
128 2XN5 FUN 4
129 1QFT HSM 4
130 3HF3 FMN 4.01146
131 5YFT RI2 4.01235
132 6BKA FMN 4.03226
133 5AHN IMP 4.03226
134 5AHM IMP 4.03226
135 1P1M MET 4.03226
136 3UXL CFI 4.03226
137 3G4G D71 4.03226
138 2ZRU FMN 4.07609
139 4KGM ATP 4.08163
140 2FLI DX5 4.09091
141 1S8G DAO 4.13223
142 2H8Z FMN 4.17827
143 2H8Z 8CM 4.17827
144 2HFU MEV 4.21687
145 4GBD MCF 4.30108
146 5V4R MGT 4.32099
147 5TVI MYR 4.34783
148 1LQY BB2 4.34783
149 3SAO NKN 4.375
150 2WPW ACO 4.42478
151 1TUK PGM 4.47761
152 3ZXE PGZ 4.51128
153 3VKC FPQ 4.54545
154 4M5P FMN 4.56989
155 3NB0 G6P 4.56989
156 4KRG SAH 4.56989
157 5GLT BGC GAL NAG GAL 4.57746
158 1Q6O LG6 4.62963
159 4IXH IMP 4.70914
160 5CX6 CDP 4.83871
161 2IDO TMP 4.83871
162 4NAO AKG 4.90798
163 1VYP FMN 4.94506
164 1VYP TNF 4.94506
165 4RC8 STE 4.95496
166 3KC1 2T6 5.04451
167 1PU7 39A 5.04587
168 3NV3 GAL NAG MAN 5.07246
169 5GVH FMN 5.09554
170 3TDC 0EU 5.10753
171 3HOK Q80 5.15021
172 4UA3 COA 5.15464
173 2GJN FMN 5.18293
174 2GJN NIS 5.18293
175 5LX9 OLB 5.21173
176 1R6N 434 5.21327
177 1GVF PGH 5.24476
178 2B4D COA 5.26316
179 4G86 BNT 5.28169
180 4XCP PLM 5.29412
181 4IJP 1EH 5.30726
182 1FX8 BOG 5.33808
183 5X3R 7Y3 5.36585
184 6CQF F97 5.38721
185 5OCS FMN 5.39084
186 6GWR FEW 5.39683
187 1JCM 137 5.40541
188 1SR7 MOF 5.40541
189 3B0P FMN 5.42857
190 3IAE D7K 5.4386
191 5VCV 1N1 5.46624
192 1MJJ HAL 5.47945
193 3E3U NVC 5.58376
194 3M3E GAL A2G NPO 5.59006
195 3WFD AXO 5.6338
196 2Q3R FMN 5.64516
197 2V6A CAP 5.64516
198 1UZD CAP 5.64516
199 2V67 CAP 5.64516
200 2V68 CAP 5.64516
201 1IR2 CAP 5.64516
202 2V63 CAP 5.64516
203 2VDH CAP 5.64516
204 1UZH CAP 5.64516
205 1IR1 CAP 5.64516
206 1TLL FMN 5.64516
207 3GUZ PAF 5.68182
208 3CEV ARG 5.68562
209 3OVR 5SP 5.70175
210 5TCI MLI 5.7971
211 2OEM 1AE 5.81114
212 1OX5 1PR 5.91398
213 1ZFJ IMP 5.91398
214 3P9T TCL 5.93607
215 6H8S FSZ 5.98007
216 3TAO PGH 5.99251
217 2WZM NA7 6.00707
218 3GWN FAD 6.14035
219 6CB2 OLC 6.14334
220 2QCD U5P 6.15385
221 2GJ5 VD3 6.17284
222 2QJY UQ2 6.1828
223 3GAY P6T 6.19195
224 5JPH COA 6.25
225 3L0E G58 6.32411
226 3QH2 3NM 6.33484
227 3EXS 5RP 6.33484
228 2GWH PCI 6.37584
229 4Q9N 0WE 6.37584
230 3GC0 AMP 6.38298
231 5CAE COA 6.38978
232 2F6U CIT 6.41026
233 3B99 U51 6.45161
234 4JEJ 1GP 6.55738
235 2DBX GLU 6.55738
236 2Y88 2ER 6.55738
237 5DG2 GAL GLC 6.66667
238 5EPQ OLA 6.70732
239 5WHU SIA 6.71141
240 1VHN FMN 6.72043
241 1WDD CAP 6.72043
242 2BTM PGA 6.74603
243 2BCG GER 6.79612
244 3W9Z FMN 6.8323
245 3B6C SDN 6.83761
246 2YMZ LAT 6.92308
247 6BVE PGA 6.93878
248 3P13 RIP 6.94444
249 6B21 C9V 6.98925
250 1YYE 196 7.08955
251 5W7B MYR 7.0922
252 5CC2 CKA 7.16981
253 4YMZ 13P 7.17131
254 2Q1H AS4 7.2
255 1S17 GNR 7.22222
256 1PS9 FMN 7.25806
257 6DIO CIT 7.25806
258 6GSG RCO 7.25806
259 3U3U EAH 7.29614
260 6BXL SAM 7.40741
261 1M5W DXP 7.40741
262 4NTK ZSP 7.43802
263 1TF9 PHI 7.74648
264 4JGX PLM 7.75194
265 1OFD AKG 7.7957
266 1OFD FMN 7.7957
267 4RJK TPP 7.7957
268 1U3R 338 7.88382
269 6BFN DL1 7.89474
270 4J24 EST 7.91667
271 4J26 EST 7.91667
272 2YJD YJD 7.91667
273 1OQC FAD 8
274 2CB8 MYA 8.04598
275 5DX3 EST 8.04598
276 5DXG EST 8.04598
277 5WGQ EST 8.04598
278 5WGD EST 8.04598
279 5DXE EST 8.04598
280 5C9J DAO 8.08081
281 3WUD GLC GAL 8.08823
282 4URX HXY 8.10811
283 2QA8 GEN 8.13953
284 5HYR EST 8.13953
285 2QZO KN1 8.13953
286 1SLT NDG GAL 8.20895
287 1W6P NDG GAL 8.20895
288 4MGD 27N 8.23529
289 4MG8 27J 8.23529
290 4TUZ 36J 8.23529
291 4MG7 27H 8.23529
292 4MGB XDH 8.23529
293 4WGF HX2 8.29268
294 4YSX E23 8.33333
295 4TV1 36M 8.36653
296 3UUD EST 8.36653
297 5K53 STE 8.39695
298 3RMK BML 8.43373
299 4NAE 1GP 8.44444
300 1ELW GLY PRO THR ILE GLU GLU VAL ASP 8.47458
301 4XJC TTP 8.47458
302 1UJP CIT 8.48709
303 4R5M NAP 8.60215
304 1ULE GLA GAL NAG 8.66667
305 6A63 LAT 8.69565
306 1BWV CAP 8.69565
307 2Z6I FMN 8.73494
308 2Z6J FMN 8.73494
309 4DOO DAO 8.78049
310 2D6M LBT 8.80503
311 1HE1 GDP 8.88889
312 3CTL S6P 9.09091
313 4UTU LRY 9.17031
314 4UTW RFW 9.17031
315 1AL8 FMN 9.1922
316 1AL8 DHP 9.1922
317 1T0S BML 9.30233
318 3OKI OKI 9.44206
319 1VKF CIT 9.57447
320 5H9Q TD2 9.67742
321 4B1M FRU FRU 9.72973
322 3R9V DXC 9.79021
323 6BMS PLM 9.97067
324 5EYW PGA 10.0402
325 3HYW DCQ 10.2151
326 3RY9 1CA 10.4
327 4DR9 BB2 10.4167
328 2TPS TPS 10.5727
329 2ALG DAO 10.8696
330 2ALG HP6 10.8696
331 5HH0 COA 11
332 2RDT FMN 11.0215
333 2RDT 2RD 11.0215
334 3WG3 A2G GAL NAG FUC 11.236
335 1NU4 MLA 11.3402
336 3FAL REA 11.5702
337 3CR3 ADP 11.5702
338 1J3R 6PG 11.5789
339 4RYV ZEA 11.6129
340 2YPI PGA 11.7409
341 5XQW 8EU 11.8483
342 4EWN 0VR 11.8577
343 1G27 BB1 11.9048
344 1JR8 FAD 11.9658
345 1DKF BMS 12.0172
346 5Y02 HBX 12.1495
347 3TAY MN0 12.2699
348 3H0A 9RA 12.2807
349 4Q4K FMN 12.3249
350 5N9Z CAP 12.3656
351 5OYA CAP 12.3656
352 3WUC GLC GAL 12.4088
353 1WW5 SGA BGC 12.5
354 2YLD CMO 12.5984
355 6BYM HC3 12.8079
356 1RBL CAP 12.844
357 1TB3 FMN 13.0682
358 6DVH FMN 13.172
359 1KBJ FMN 13.172
360 3BW2 FMN 13.2791
361 4XP7 FNR 13.2948
362 5C1M OLC 13.6
363 5NFB 8VT 13.6364
364 2PRG BRL 13.6364
365 3KPE TM3 13.7255
366 6FS0 E4W 13.8365
367 2WOR 2AN 15
368 4NG2 OHN 15.0442
369 4V3I ASP LEU THR ARG PRO 15.1751
370 1TRD PGH 15.2
371 1YRX FMN 15.7025
372 1HBK MYR 15.7303
373 1NF8 BOG 15.942
374 2NLI LAC 16.8478
375 2NLI FMN 16.8478
376 1LYX PGA 17.3387
377 4JLS 3ZE 17.7632
378 3E70 GDP 17.9878
379 3OIX FMN 18.5507
380 4V1F BQ1 18.6047
381 4RRG A3T 19.1489
382 4OGQ 7PH 19.3548
383 4OGQ UMQ 19.3548
384 4XDA ADP 19.4175
385 5MWE TCE 19.7531
386 1KBI FMN 19.8925
387 1KBI PYR 19.8925
388 4RJD TFP 22.7273
389 5W97 CHD 23.2877
390 5ZCO CHD 23.2877
391 5Z84 CHD 23.2877
392 2DYS PGV 23.2877
393 5ZCO PGV 23.2877
394 5Z84 PGV 23.2877
395 5Z84 TGL 23.2877
396 2Y69 CHD 25.6757
397 5OCA 9QZ 30.9524
398 5TBM 79A 32.1739
399 1GTE IUR 35.2151
400 1GTE FMN 35.2151
401 3MJY IJZ 39.0173
402 3MJY FMN 39.0173
403 4WZH FMN 41.2104
404 3C3N FMN 41.6667
405 1OVD ORO 45.6592
406 1OVD FMN 45.6592
407 1EP2 ORO 47.91
408 1EP2 FMN 47.91
409 3BEJ MUF 48
410 1RDT L79 48
Pocket No.: 3; Query (leader) PDB : 4IGH; Ligand: FMN; Similar sites found with APoc: 410
This union binding pocket(no: 3) in the query (biounit: 4igh.bio1) has 88 residues
No: Leader PDB Ligand Sequence Similarity
1 1IS3 LAT None
2 4WG0 CHD None
3 4JIQ FMN 1.34409
4 4JIQ 1L5 1.34409
5 5MTE BB2 1.45985
6 2WD7 VGD 1.49254
7 5OSW DIU 1.6129
8 2GUD BMA 1.63934
9 2GUD MAN 1.63934
10 2HYR BGC GLC 1.63934
11 4LH7 NMN 1.85759
12 5NM7 GLY 1.8797
13 5E70 RCD 1.88172
14 4MRP GSH 1.88172
15 2GOU FMN 1.88172
16 2B56 U5P 1.88172
17 4M26 AKG 1.92308
18 4Q0P 0MK 1.92308
19 4K10 NI9 1.9337
20 5Z21 OXM 1.95531
21 2FJK 13P 1.96721
22 1QDS PGA 1.99203
23 3T03 3T0 2.11268
24 5YRF GLC GLC 2.11268
25 5A7V MAN 2.15054
26 5A7V BMA 2.15054
27 4CW5 FMN 2.20264
28 1A78 TDG 2.23881
29 4TX6 38B 2.25806
30 5K52 OCD 2.26415
31 3HQ9 OXL 2.31884
32 3GLC R5P 2.37288
33 2R14 FMN 2.38727
34 2R14 TXD 2.38727
35 1ICP FMN 2.41935
36 1OYB FMN 2.41935
37 5U97 PIT 2.41935
38 1OYB HBA 2.41935
39 6C4A PYR 2.41935
40 2UZ1 TPP 2.41935
41 3UIM ANP 2.45399
42 2GJ3 FAD 2.5
43 5N5U 7N8 2.54777
44 6FOF LAT 2.55102
45 3WBZ ATP 2.58303
46 3O01 DXC 2.5974
47 5H2U 1N1 2.62172
48 3KP6 SAL 2.64901
49 2UW1 GVM 2.66272
50 3ATY FMN 2.68817
51 2O1V ADP 2.68817
52 3WV6 GAL BGC 2.7027
53 3WV6 GAL GLC 2.7027
54 5M0T AKG 2.72109
55 4BI7 PGA 2.72374
56 2ZFU SAH 2.7907
57 4A3U FMN 2.7933
58 1SW0 PGA 2.82258
59 3GYT DL4 2.86885
60 1C1L GAL BGC 2.91971
61 2HHP FLC 2.95699
62 3TII ANP 2.95699
63 1GNI OLA 2.95699
64 4XNV BUR 2.95699
65 4UZI IMD 2.95699
66 5AZC PGT 3
67 4ELG 52J 3.01205
68 5KAU RHQ 3.0303
69 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 3.06122
70 6BR9 6OU 3.06407
71 3FRQ ERY 3.07692
72 4O08 PO6 3.11526
73 3TL1 JRO 3.14465
74 6BR8 PGV 3.1746
75 6BR8 6OU 3.1746
76 5G5W R8C 3.21429
77 4QNW FMN 3.22581
78 6BFG FMN 3.22581
79 4QO5 NAG 3.22581
80 1US2 XYP XYP XYP XYP 3.22581
81 1P4C FMN 3.22581
82 4OKD GLC GLC GLC 3.22581
83 5Z5I XYP 3.22581
84 3T1A 5MA 3.22581
85 1Z48 FMN 3.25444
86 1Z44 FMN 3.25444
87 1Z42 FMN 3.25444
88 1Z41 FMN 3.25444
89 2BLE 5GP 3.26975
90 3W54 RNB 3.34347
91 5VJE GOS 3.35196
92 4B16 NAG 3.38346
93 4UXL 5P8 3.41615
94 2C6Q IMP 3.4188
95 2BHW NEX 3.44828
96 2Q3O FMN 3.49462
97 1DJN FMN 3.49462
98 5ABH YWN 3.49462
99 3KRU FMN 3.49854
100 5HCV 60R 3.50195
101 4CL6 7SB 3.50877
102 3BQD DAY 3.52941
103 4P6X HCY 3.52941
104 5CSS G3P 3.53982
105 3X01 AMP 3.56234
106 2BJ4 OHT 3.57143
107 3N9R TD3 3.58306
108 4N02 FNR 3.64146
109 5O1I 9GH 3.65297
110 6D28 NEC 3.663
111