Receptor
PDB id Resolution Class Description Source Keywords
4J0Q 2.29 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF PSEUDOMONAS PUTIDA ELONGATION FACTOR TU PSEUDOMONAS PUTIDA TRANSLATION GDP GTP GTPASE ELONGATION PSEUDOMONAS
Ref.: HUMAN OXYGEN SENSING MAY HAVE ORIGINS IN PROKARYOTI ELONGATION FACTOR TU PROLYL-HYDROXYLATION PROC.NATL.ACAD.SCI.USA V. 111 13331 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG C:401;
E:401;
A:401;
D:401;
B:401;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
GDP C:402;
E:402;
A:402;
D:402;
B:402;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
MES E:403;
B:403;
A:403;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
195.237 C6 H13 N O4 S C1COC...
MPD A:404;
D:403;
A:405;
E:404;
C:403;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
submit data
118.174 C6 H14 O2 C[C@@...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4J0Q 2.29 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF PSEUDOMONAS PUTIDA ELONGATION FACTOR TU PSEUDOMONAS PUTIDA TRANSLATION GDP GTP GTPASE ELONGATION PSEUDOMONAS
Ref.: HUMAN OXYGEN SENSING MAY HAVE ORIGINS IN PROKARYOTI ELONGATION FACTOR TU PROLYL-HYDROXYLATION PROC.NATL.ACAD.SCI.USA V. 111 13331 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 4J0Q - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (14)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1D2E Kd = 1 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1DG1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 2BVN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
4 1EFC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 4H9G - 14J C5 H3 Br O3 c1cc(oc1C(....
6 4LBZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
7 4LC0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 1EXM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
9 2C78 - PUL C47 H66 O13 C[C@@H]1[C....
10 1EFT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
11 4LBV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
12 4LBW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
13 1HA3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
14 4J0Q - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (17)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1D2E Kd = 1 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1DG1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 2BVN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
4 1EFC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 4H9G - 14J C5 H3 Br O3 c1cc(oc1C(....
6 4LBZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
7 4LC0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 1EXM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
9 2C78 - PUL C47 H66 O13 C[C@@H]1[C....
10 1EFT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
11 4LBV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
12 4LBW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
13 1HA3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
14 4J0Q - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
15 1SKQ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
16 1JNY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
17 3WYA - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4J0Q; Ligand: GDP; Similar sites found: 509
This union binding pocket(no: 1) in the query (biounit: 4j0q.bio1) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1P9B GDP 0.000004835 0.57736 1.15473
2 4FRZ ADP 0.000002647 0.54139 1.29534
3 3COB ADP 0.0000004003 0.55639 1.35501
4 2ZPT A3P 0.01242 0.44662 1.35593
5 1R6B ADP 0.00007124 0.51157 1.38568
6 2OG2 MLI 0.00001189 0.42495 1.39276
7 1ZUA TOL 0.04711 0.41522 1.57729
8 1ZUA NAP 0.04711 0.41522 1.57729
9 1XP8 AGS 0.00004417 0.51497 1.63934
10 3B9Q MLI 0.000008211 0.57254 1.65563
11 1SVK ALF GDP 0.0000000003875 0.81185 1.69972
12 1JWY GDP 0.000000006612 0.71427 1.84758
13 5I34 GDP 0.000001088 0.59911 1.84758
14 1XKV ATP 0.00004293 0.52519 1.84758
15 1G41 ADP 0.00004359 0.52487 1.84758
16 1JWY ADP 0.00003778 0.52485 1.84758
17 3FYH ADP 0.0001465 0.51566 1.86335
18 4BFW ZVW 0.0001876 0.53211 1.88679
19 3DZD ADP 0.0005313 0.47468 1.90217
20 1BH2 GSP 0.000000001106 0.78571 1.90476
21 1WF3 GNP 0.0000000000852 0.83669 1.99336
22 2QEN ADP 0.00000753 0.56791 2
23 2F9L GDP 0.0000000001473 0.81466 2.01005
24 2DPY ADP 0.00004816 0.52095 2.07852
25 3ZL8 ADP 0.02055 0.4024 2.07852
26 1FWY UD1 0.01519 0.40899 2.1148
27 2B8W ALF 5GP 0.0001887 0.51012 2.13415
28 2ZFI ADP 0.00001062 0.52749 2.18579
29 3MD0 GDP 0.000000000008843 0.83305 2.25352
30 2GDJ ANP 0.0001819 0.48896 2.27273
31 2ZR9 DTP 0.0000307 0.52594 2.29226
32 2BIF ANP 0.0001426 0.5301 2.30947
33 2BIF SIN 0.0002394 0.5301 2.30947
34 2XAU ADP 0.0002224 0.49052 2.30947
35 5MZN ADP 0.0009615 0.45746 2.30947
36 4A4Z ANP 0.001315 0.44783 2.30947
37 2HV8 GTP 0.0000000004922 0.79487 2.32558
38 1RRC ADP 0.000004708 0.5126 2.32558
39 5KSZ GCP 0.0000001414 0.58085 2.35849
40 2D7C GTP 0.0000000001926 0.81551 2.39521
41 1JJV ATP 0.000008588 0.52279 2.42718
42 3E70 GDP 0.0000003054 0.62571 2.43902
43 2JAQ DCP 0.002639 0.45059 2.43902
44 4GBM A3P 0.0002638 0.50082 2.47678
45 4LPS GDP 0.000000004931 0.71209 2.47934
46 1K6M AGS 0.00007874 0.52717 2.54042
47 1Z6T ADP 0.00007603 0.44187 2.54042
48 1QHG ATP 0.0104 0.41147 2.54042
49 3FWY ADP 0.0000004626 0.62745 2.54777
50 3ZFD ANP 0.00002239 0.53891 2.5641
51 2VVG ADP 0.0000001744 0.54902 2.57143
52 1U0J ADP 0.0003697 0.47115 2.62172
53 5KSP GDP 0.00000001547 0.63521 2.63158
54 2WPW ACO 0.01762 0.40021 2.65487
55 1G6O ADP 0.00005055 0.47037 2.72727
56 5HR5 ADP 0.0000461 0.52924 2.77136
57 5I0H ADP BEF 0.00008257 0.52168 2.77136
58 4P32 ADP 0.0001523 0.51067 2.77136
59 2VF7 ADP 0.00018 0.49217 2.77136
60 5HR5 FLC 0.02319 0.41366 2.77136
61 3TMK T5A 0.0001117 0.5291 2.77778
62 5MEX SZZ 0.004251 0.45808 2.79503
63 5MEX PAP 0.00143 0.45808 2.79503
64 4QRH 0O2 0.006008 0.4291 2.85714
65 3QXC ATP 0.00005317 0.54189 2.89256
66 4FCW ADP 0.00007847 0.50954 2.89389
67 2F3R G5P 0.01095 0.43069 2.89855
68 4QM7 GTP 0.00005246 0.5148 2.92398
69 1D2N ANP 0.000748 0.47411 2.94118
70 4LJ9 ACP 0.0001248 0.49678 2.94985
71 2IXE ATP 0.0001554 0.51024 2.95203
72 1ZUI SKM 0.0001049 0.54001 2.97619
73 1FNN ADP 0.0001467 0.4278 3.00231
74 1OYY AGS 0.006139 0.41576 3.00231
75 1Q19 APC 0.01302 0.41405 3.00231
76 1BXK NAD 0.03675 0.40082 3.00231
77 2WKQ GTP 0.00000003924 0.52224 3.01205
78 4KBF AMP 0.003691 0.42366 3.0137
79 1QF5 GDP 0.00001825 0.59715 3.01624
80 1QF5 RPL 0.003177 0.50487 3.01624
81 3BFX A3P 0.0003139 0.49064 3.04054
82 3B7G ANP 0.0006137 0.46648 3.04348
83 1HXD BTN 0.01941 0.40007 3.11526
84 1A5Z NAD 0.01964 0.40665 3.1348
85 3GJ5 GDP 0.00000000009472 0.79484 3.16742
86 3GJ4 GDP 0.0000000001923 0.77495 3.16742
87 3GJ0 GDP 0.000000000131 0.74938 3.16742
88 1V8K ANP 0.00001923 0.53566 3.17073
89 1Z06 GNP 0.0000000001306 0.82074 3.1746
90 4IHQ ADP 0.0001043 0.49726 3.23326
91 4IOK ADP 0.0004949 0.4943 3.23326
92 4IOK XPO 0.0003886 0.4943 3.23326
93 4PJ3 ANP 0.001836 0.40666 3.23326
94 4KFU ACP 0.000002225 0.54585 3.30189
95 4R2I ANP 0.0008943 0.459 3.33333
96 2GWH A3P 0.001342 0.45728 3.3557
97 1AQU A3P 0.0009619 0.46439 3.367
98 1BG2 ADP 0.00000008585 0.55986 3.38462
99 1TAD GDP 0.0000000002357 0.82015 3.39506
100 1TAD ALF 0.0000000002357 0.52815 3.39506
101 5X40 ACP 0.0002721 0.50014 3.42466
102 1B0U ATP 0.0001327 0.50412 3.43511
103 1SVM ATP 0.0002107 0.53751 3.44828
104 1OFH ADP 0.00009324 0.50884 3.44828
105 5GJC ATP 0.0001075 0.48263 3.4642
106 3TBK ANP 0.001076 0.44224 3.4642
107 1OE0 TTP 0.003632 0.44853 3.47826
108 1G6H ADP 0.00000282 0.50356 3.50195
109 4GOX A3P 0.00004468 0.53952 3.51438
110 2ODE ALF GDP 0.0000000002604 0.81792 3.5461
111 1DAK DPU 0.0002074 0.53225 3.57143
112 4GDX GLU 0.006046 0.42646 3.58974
113 3REF GDP 0.00000001329 0.71342 3.60825
114 3VX3 ADP 0.00004113 0.53426 3.62903
115 3P4X ADP 0.0000327 0.52117 3.63196
116 3TK1 GDP 0.00000000001529 0.79694 3.63636
117 3H86 AP5 0.0001537 0.52988 3.64583
118 1W0J ADP 0.000003247 0.58282 3.67647
119 1W0J ADP BEF 0.0001168 0.51186 3.67647
120 1YZN GNP 0.000000001006 0.78214 3.69515
121 4PFO ADP 0.00009863 0.52632 3.69515
122 4ZG4 VO4 ADP 0.00007917 0.40775 3.69515
123 3H4S ADP 0.0000006981 0.54603 3.7037
124 4KOT CE3 0.03743 0.40888 3.7037
125 1CR1 TTP 0.00004018 0.53722 3.71622
126 1J99 AND 0.004962 0.44985 3.75427
127 1G3Q ADP 0.000002656 0.58043 3.79747
128 1M7B GTP 0.000000005777 0.57096 3.80435
129 2XTN GTP 0.000001254 0.6174 3.84615
130 1JJ7 ADP 0.000001398 0.51453 3.84615
131 2IYL GDP 0.0000003189 0.62086 3.87324
132 4NE2 ADP 0.00002821 0.56832 3.89222
133 4NE2 SH2 0.00003229 0.56832 3.89222
134 1YZG GDP 0.000000000003182 0.86588 3.91061
135 1X6V ADP 0.00003173 0.55713 3.9261
136 2AWN ADP 0.0000004926 0.50988 3.93701
137 3IUY AMP 0.00984 0.40591 3.94737
138 4H6U ACO 0.02074 0.40386 4
139 3ZQ6 ADP ALF 0.000003823 0.60004 4.01235
140 4AG5 ADP 0.000008364 0.5658 4.08163
141 2FFQ GSP 0.0000000002432 0.81351 4.09357
142 1ION ADP 0.000008628 0.55901 4.11523
143 1W5T ANP 0.0004159 0.48679 4.12621
144 1W5T ADP 0.0005901 0.47482 4.12621
145 4DID GDP 0.000000004944 0.71204 4.14508
146 1IWE IMP 0.00003 0.61863 4.15704
147 2ZPA ADP 0.0001215 0.51101 4.15704
148 1NY5 ADP 0.000336 0.48684 4.15704
149 3DKP ADP 0.0003784 0.47373 4.15704
150 1A4R GDP 0.000000007738 0.71838 4.18848
151 1A4R GNH 0.000000009195 0.71107 4.18848
152 2NGR GDP 0.000000008034 0.70187 4.18848
153 1GRN GDP 0.00000001785 0.69691 4.18848
154 1SQ5 ADP 0.000004355 0.57007 4.22078
155 4TMK T5A 0.006957 0.44219 4.22535
156 1E2K TMC 0.00008976 0.54907 4.22961
157 5BQ5 ADP BEF 0.00005611 0.47197 4.2328
158 2XTZ GSP 0.0000000001328 0.8237 4.23729
159 1OXV ANP 0.00004323 0.51542 4.24929
160 1L2T ATP 0.0001972 0.50916 4.25532
161 4HSE ADP 0.00003985 0.52373 4.28212
162 5WRJ A3P 0.0003711 0.49531 4.29043
163 5EP2 AZU 0.02285 0.40008 4.29688
164 1T5C ADP 0.0000002271 0.54374 4.29799
165 3RWO GDP 0.0000000001113 0.82757 4.32432
166 3ZS9 ADP ALF 0.000004462 0.59663 4.38799
167 1YQT ADP 0.00001226 0.51255 4.38799
168 1W4R TTP 0.0003162 0.50424 4.38799
169 2ORV 4TA 0.002586 0.45444 4.38799
170 2WOJ ADP ALF 0.000004921 0.42732 4.38799
171 4YS0 ADP 0.001401 0.40493 4.38799
172 1NJF ADP 0.00001504 0.55585 4.4
173 1NJF AGS 0.0000211 0.55355 4.4
174 4P4T GDP 0.000000006815 0.57957 4.44444
175 4U5X GNP 0.00000001031 0.71221 4.49438
176 4B5P ACO 0.03028 0.40271 4.5
177 5N69 ADP 0.00006345 0.45654 4.52261
178 5E5U MLI 0.002957 0.42359 4.52261
179 4YMU ATP 0.00007651 0.50364 4.54545
180 3EC1 GDP 0.00000000004999 0.80822 4.60705
181 4NON GDP 0.0000000007654 0.7911 4.61538
182 3PQC GDP 0.00000002035 0.68653 4.61538
183 1P72 ADP 0.0001583 0.52621 4.61894
184 3FB4 AP5 0.0006385 0.50392 4.62963
185 1QF9 C5P 0.00103 0.48931 4.63918
186 2GJ8 ALF GDP 0.00000000002542 0.57609 4.65116
187 2BEK ATP 0.0005795 0.50371 4.66926
188 5CK5 GDP 0.000000002844 0.71399 4.74684
189 1BO4 COA 0.00279 0.43219 4.7619
190 4ITM ATP 0.02182 0.40731 4.7619
191 1GOJ ADP 0.000000175 0.66625 4.78873
192 1IN4 ADP 0.00003653 0.5368 4.79042
193 3BFV ADP 0.000002633 0.55527 4.79705
194 1IHU AF3 0.000001266 0.61457 4.84988
195 1IHU ADP 0.000001428 0.61457 4.84988
196 4WZ6 ATP 0.00001921 0.54733 4.84988
197 2Z5F A3P 0.0008461 0.47146 4.84988
198 1YTM ATP 0.00001751 0.45196 4.84988
199 4IDN GNP 0.00005807 0.42216 4.84988
200 3D2M COA 0.03758 0.40031 4.84988
201 2ZEJ GDP 0.0000000007049 0.79 4.8913
202 2Q2Y ADP 0.0001217 0.54207 4.90463
203 2Q2Y MKR 0.0001184 0.54139 4.90463
204 3LOO B4P 0.02425 0.417 4.93151
205 3B5J 12D 0.00006678 0.49539 4.93827
206 5HGZ ACO 0.01235 0.41993 4.93827
207 3DC4 ADP 0.00001949 0.51758 4.94186
208 1ZIN AP5 0.0003319 0.51898 5.06912
209 4MKF AP5 0.0005422 0.50886 5.06912
210 5LB3 ADP 0.0002768 0.47712 5.08083
211 4IEE AGS 0.002103 0.43528 5.08083
212 2PL3 ADP 0.0003953 0.46977 5.08475
213 3GJ7 GDP 0.0000000001406 0.78145 5.10204
214 3KJI ADP 0.000004963 0.57382 5.11811
215 4KVX ACO 0.02226 0.40828 5.12821
216 2WIC GNP 0.0000000001203 0.72497 5.24345
217 5KUT GDP 0.000000002758 0.72426 5.29101
218 4D81 ADP 0.0000324 0.46958 5.30035
219 2FAH GDP 0.00001447 0.55112 5.31178
220 4R43 GDP 0.00000805 0.53441 5.31178
221 1OS1 ATP 0.000102 0.53113 5.31178
222 1OS1 PYR 0.0001101 0.53113 5.31178
223 2WHX ADP 0.00003089 0.49659 5.31178
224 2JLR ANP 0.0002105 0.49432 5.31178
225 3RAB GNP 0.000000000184 0.81652 5.32544
226 4HDO GNP 0.000000002404 0.7629 5.38922
227 1JI0 ATP 0.00002646 0.53365 5.41667
228 1KY3 GDP 0.0000000005082 0.7687 5.49451
229 3UIE ANP 0.0000197 0.54162 5.5
230 2GK6 ADP 0.002054 0.42839 5.54273
231 5BXQ GDP 0.0000000000617 0.80381 5.55556
232 4HAT GNP 0.00000000171 0.77327 5.55556
233 1IBR GNP 0.000000002444 0.76254 5.55556
234 1H65 GDP 0.000002472 0.60007 5.55556
235 5L3W GDP 0.000001322 0.59855 5.55556
236 5GVR LMR 0.001358 0.43407 5.55556
237 2W9S NDP 0.02868 0.40393 5.59006
238 5L3V GDP 0.0000001295 0.57923 5.68562
239 1Q20 PLO 0.002804 0.46277 5.68562
240 5L3S GNP 0.0000004402 0.47735 5.74324
241 5L3S G 0.01953 0.40044 5.74324
242 2FSH ANP 0.002267 0.43373 5.77367
243 5M04 GDP 0.00000000000661 0.83905 5.83333
244 1ZRH A3P 0.02074 0.4022 5.83942
245 1XMV ADP 0.00001967 0.53851 5.89888
246 2QQ0 THM 0.00006917 0.54152 5.97826
247 2QQ0 ANP 0.0000802 0.54152 5.97826
248 2QQ0 TMP 0.00008911 0.53915 5.97826
249 2PZ8 APC 0.02023 0.40441 5.98592
250 2CK3 ANP 0.0001453 0.42557 6
251 3WQT ANP 0.01737 0.40774 6.00462
252 1TQ4 GDP 0.0000000007461 0.59506 6.05327
253 3T1O GDP 0.0000000000173 0.83556 6.06061
254 2V7Q ATP 0.000003538 0.5778 6.06061
255 2V7Q ADP 0.0001086 0.49968 6.06061
256 1NST A3P 0.0006072 0.47421 6.15385
257 1M7G AV2 0.000001385 0.58638 6.16114
258 1M7G ADX 0.0000101 0.58638 6.16114
259 1M7G ADP 0.0000225 0.56478 6.16114
260 4LC1 GDP 0.000000000125 0.74854 6.23145
261 1NF3 GNP 0.00000005921 0.49653 6.25
262 3NC9 TR3 0.04099 0.40768 6.38978
263 2C9O ADP 0.00005639 0.52991 6.46651
264 1YRB GDP 0.0000000001051 0.80213 6.48855
265 1LVG ADP 0.0000005708 0.58858 6.56566
266 1KAO GDP 0.000000000426 0.77663 6.58683
267 4DCT GDP 0.00000000004188 0.81192 6.69746
268 2BCG GDP 0.0000000002618 0.79106 6.79612
269 3M1I GTP 0.000000001534 0.77282 6.80628
270 1WA5 GTP 0.000000002956 0.76894 6.81818
271 2Y65 ADP 0.0000002606 0.56353 6.84932
272 4PX9 ADP 0.000103 0.49752 6.84932
273 1KO8 6PG 0.0001907 0.50133 6.85714
274 3NHB ADP 0.00001096 0.51488 6.86275
275 3RLF ANP 0.0001549 0.51242 6.92841
276 2QG6 NMN 0.0002107 0.51324 7.03518
277 1EK0 GNP 0.000000004236 0.74752 7.05882
278 2G77 GDP 0.000000000009981 0.69468 7.07071
279 2G77 AF3 0.006153 0.42307 7.07071
280 2NCD ADP 0.00000219 0.5949 7.14286
281 4QOS ADP 0.0001161 0.45734 7.16981
282 5H56 ADP 0.00005356 0.54724 7.17949
283 5H56 TYD 0.00005356 0.54724 7.17949
284 3AB3 GDP 0.0000000000608 0.82642 7.31707
285 1M2O GNP 0.0000000008568 0.78268 7.36842
286 1MKY GDP 0.0000000000007316 0.89074 7.3903
287 3RC3 ANP 0.003038 0.42769 7.3903
288 3IQE F42 0.03869 0.40195 7.3903
289 4M7V NAP 0.01362 0.42574 7.42857
290 1FQK GDP 0.0000000003049 0.79881 7.48299
291 2RCN GDP 0.00000000001708 0.82526 7.5419
292 2J0V GDP 0.000000002343 0.72767 7.54717
293 5L3R GCP 0.0000003152 0.48113 7.6412
294 2OFW ADX 0.0000403 0.56613 7.69231
295 1B7T ADP 0.00006552 0.51628 7.69231
296 3T5G GDP 0.00000000008951 0.80091 7.73481
297 1G3M PCQ 0.003296 0.46503 7.82313
298 1O3Y GTP 0.00000000004548 0.84028 7.83133
299 4MKG AP5 0.0004678 0.51108 7.8341
300 1S3G AP5 0.0006259 0.50438 7.8341
301 5TSH ANP 0.00001696 0.53827 7.85219
302 5TSH ADP 0.00002921 0.49837 7.85219
303 3BD9 A3P 0.00284 0.43438 7.85714
304 4PSW COA 0.009276 0.41391 7.89474
305 1VM6 NAD 0.01979 0.4109 7.89474
306 2ZE7 DST 0.003985 0.44648 7.90514
307 1S8F GDP 0.0000000002349 0.8173 7.9096
308 1XTQ GDP 0.000000000269 0.80153 7.9096
309 2W58 ADP 0.000003535 0.50025 7.92079
310 1S9D GDP 0.000000000005187 0.77959 7.92683
311 1FP6 ADP 0.000003317 0.58236 7.95848
312 1ZJ6 G3D 0.00000000000339 0.86456 8.02139
313 4CVN ADP 0.000005568 0.5439 8.0292
314 4ZNL BEF ADP 0.00001811 0.50216 8.0292
315 2VB6 ADP BEF 0.00009076 0.52407 8.05369
316 3BOS CDP 0.00001178 0.54585 8.26446
317 1FZQ GDP 0.000000000002801 0.86284 8.28729
318 4AVB ACO 0.02919 0.40083 8.31409
319 2OM2 GDP 0.0000000001437 0.62483 8.33333
320 2QTV GNP 0.000000002587 0.75534 8.38323
321 2B8T THM 0.002161 0.45312 8.52018
322 1VHT BA3 0.000096 0.50823 8.54503
323 4U00 ADP 0.000002409 0.50614 8.60656
324 1GUA GNP 0.000000001526 0.5276 8.64198
325 1QHH ATP 0.01412 0.40069 8.69565
326 1NRJ GTP 0.000000003007 0.74224 8.7156
327 1GXU 2HP 0.0009005 0.44493 8.79121
328 4TTQ ATP 0.00002427 0.53082 8.83721
329 3QKT ANP 0.0002449 0.50441 8.84956
330 4ITR GDP 0.00000002107 0.69688 8.86076
331 1UKZ ADP 0.0004066 0.50642 8.86699
332 4WOP CTP 0.000585 0.40138 8.88889
333 1CJW COT 0.01182 0.42514 9.03614
334 1Z0A GDP 0.00000000005502 0.81117 9.1954
335 2HF9 GSP 0.000000004782 0.60176 9.29204
336 2XT3 ADP 0.0000007502 0.54589 9.30233
337 4K81 GTP 0.00000000412 0.75376 9.35672
338 3CX8 GSP 0.0000000002083 0.8229 9.35961
339 3IIJ ADP 0.000004279 0.56689 9.44444
340 1VKJ A3P 0.002508 0.44799 9.47368
341 1Z0F GDP 0.00000000003483 0.81578 9.49721
342 2PEZ DAT 0.00002117 0.57151 9.49721
343 4BAS GNP 0.0000000007507 0.77575 9.54774
344 1PUJ GNP 0.00000000002097 0.83632 9.57447
345 2UZI GTP 0.0000000006298 0.78945 9.63855
346 1WQ1 GDP 0.00000000101 0.77269 9.63855
347 1NVU GTP 0.000000001799 0.76931 9.63855
348 1NVV GNP 0.000000002059 0.76633 9.63855
349 3DDC GNP 0.000000002489 0.76214 9.63855
350 1CLU DBG 0.000000003237 0.42249 9.63855
351 2CHG ANP 0.00004321 0.53062 9.73451
352 1F9V ADP 0.00000314 0.53868 9.79827
353 3KTA AP5 0.00006595 0.51894 9.82659
354 3KUD GDP 0.000000000506 0.7807 9.87654
355 1E96 GTP 0.0000000524 0.69219 9.89583
356 3DEF GDP 0.000001007 0.60765 9.92366
357 1Z0J GTP 0.0000000004544 0.7997 10
358 1UPT GTP 0.0000000004529 0.78671 10
359 1G16 GDP 0.000000002575 0.74901 10
360 3QF7 ANP 0.0001728 0.50345 10
361 4HI0 GDP 0.000000002394 0.58644 10.0503
362 1YVD GNP 0.000000000741 0.78587 10.0592
363 3SBD GNP 0.00000006319 0.49657 10.1604
364 1GWN GTP 0.00000001295 0.71073 10.2439
365 2W2X GSP 0.00000000884 0.71897 10.2703
366 4C4P GNP 0.0000000002664 0.8115 10.2804
367 1LFD GNP 0.000000001141 0.77638 10.3448
368 5HCN GCP 0.000000006201 0.65742 10.3448
369 4HUT ATP 0.02249 0.41196 10.4712
370 1D5C GDP 0.00000000006392 0.81711 10.4938
371 1QSN COA 0.02094 0.40025 10.4938
372 3MGB PAP 0.002378 0.44914 10.6583
373 2FJU GSP 0.00000002725 0.69467 10.6742
374 1U8Z GDP 0.0000000004007 0.79285 10.7143
375 3A4M ADP 0.000001829 0.56471 10.7692
376 1VG1 GDP 0.00000000001332 0.83591 10.8108
377 1VG9 GDP 0.00000000005316 0.80693 10.8108
378 3QBT GNP 0.0000000005636 0.55157 10.9195
379 2CJW GDP 0.00000000002152 0.82046 10.9375
380 2KIN ADP 0.0000001034 0.55649 11
381 1P3D ANP 0.009905 0.41827 11.0855
382 4DSU GDP 0.0000000003748 0.80396 11.1111
383 5UQW GDP 0.0000000003151 0.80145 11.1111
384 4WZA ADP 0.00004639 0.58424 11.2319
385 4WZA ACP 0.00004639 0.58424 11.2319
386 2A5J GDP 0.0000000000657 0.70949 11.3164
387 5TB5 GDP 0.00000000009205 0.80032 11.3514
388 5TAR GDP 0.0000000001457 0.67417 11.3514
389 1T8U A3P 0.001076 0.46626 11.3971
390 1T8U UAP SGN IDS SGN 0.003436 0.46516 11.3971
391 3CH5 GDP 0.00000000004477 0.81053 11.5385
392 2RGX AP5 0.0009903 0.49607 11.6505
393 3T12 GDP ALF 0.00000000005408 0.61719 11.7647
394 4NCN GTP 0.0000000001929 0.80879 11.7783
395 2CE7 ADP 0.00003055 0.53236 11.7783
396 3BC1 GNP 0.000000000822 0.78359 11.8644
397 2GCN GDP 0.00000001097 0.71758 11.9403
398 2GCO GNP 0.0000000114 0.70648 11.9403
399 1RJ9 GCP 0.000002306 0.63779 12
400 2HT6 GDP 0.000000000005664 0.84224 12.069
401 2C04 GCP 0.000002785 0.50613 12.1212
402 2QZ4 ADP 0.00003315 0.53064 12.2137
403 5XCO GDP 0.0000000002829 0.78113 12.2807
404 4M9Q GNP 0.000000000002664 0.89811 12.3348
405 1Z08 GNP 0.0000000006457 0.78245 12.3529
406 1MH1 GNP 0.00000001591 0.50068 12.3656
407 5O2T GSP 0.0000000006563 0.53854 12.426
408 1G4U GDP 0.00000002964 0.68956 12.5
409 1OIX GDP 0.0000000001662 0.81876 12.5654
410 1OIV GDP 0.0000000002134 0.81326 12.5654
411 5UFQ GNP 0.0000000004007 0.55276 12.6506
412 1ZD9 GDP 0.0000000000885 0.64264 12.7021
413 2VBQ BSJ 0.01241 0.43132 12.7273
414 1FL2 FAD 0.04461 0.40658 12.9032
415 1YZQ GNP 0.0000000001605 0.82269 12.9412
416 4V0K GDP 0.00000000007203 0.83377 13.0178
417 1NN5 ANP 0.0000552 0.54827 13.0233
418 2D2F ADP 0.0001213 0.42812 13.6
419 1DAR GDP 0.000000000001897 0.87094 13.6259
420 1AZT GSP 0.0000000001174 0.83567 13.6259
421 1F6B GDP 0.00000000002878 0.81978 13.6364
422 1ZC3 GNP 0.0000000009389 0.78367 13.7143
423 4OI4 ATP 0.000112 0.51949 13.913
424 5UWP GNP 0.000000001347 0.77855 13.9241
425 5UWI GNP 0.000000001428 0.77441 13.9241
426 5UWR GNP 0.000000001583 0.77214 13.9241
427 5UWQ GNP 0.000000001272 0.53259 13.9241
428 5DIF GNP 0.000000001266 0.53219 13.9241
429 5UWU GNP 0.0000000013 0.53178 13.9241
430 5UWO GNP 0.000000001467 0.53081 13.9241
431 5UWH GNP 0.000000001466 0.53056 13.9241
432 5UWJ GNP 0.000000001491 0.53035 13.9241
433 5UWW GNP 0.000000001553 0.53027 13.9241
434 5DHF GNP 0.000000001811 0.52916 13.9241
435 5UWS GNP 0.000000001741 0.51936 13.9241
436 5DI9 GNP 0.000000002061 0.51747 13.9241
437 1KUV CA5 0.01461 0.42415 14.0097
438 1G7S GDP 0.0000000000002421 0.83436 14.0878
439 1XX6 ADP 0.0003191 0.47728 14.1361
440 1FQJ GDP 0.0000000001673 0.59019 14.2857
441 1RE0 GDP 0.000000000003662 0.85123 14.4796
442 2A5F GTP 0.00000000002714 0.85515 14.5078
443 3W5J GDP 0.00000001214 0.62138 14.7059
444 4XTR ADP 0.000002333 0.48922 14.7826
445 4XTR ATP 0.000003372 0.45487 14.7826
446 4XVU ATP 0.000004382 0.45226 14.7826
447 1Z2A GDP 0.0000000001199 0.59237 14.881
448 1CS4 GSP 0.0000000002511 0.54055 14.9746
449 2D7D ADP 0.001817 0.44111 15
450 3GJ3 GDP 0.00000000007531 0.79443 15.1515
451 3FVQ ATP 0.0002307 0.4995 15.3203
452 3Q85 GNP 0.0000000000057 0.84807 15.3846
453 1VG8 GNP 0.0000000002898 0.80964 15.4589
454 1VG0 GDP 0.00000000007735 0.80863 15.4589
455 1DS6 GDP 0.000000002013 0.72613 15.625
456 1I4D GDP 0.000000003846 0.70777 15.625
457 1R4A GNP 0.00000000009264 0.82826 15.6863
458 5KDO GDP 0.000000000274 0.61772 16.2162
459 3Q72 GNP 0.00000000006355 0.79238 16.2651
460 3GJ8 GDP 0.00000000007543 0.73403 16.3043
461 1GOT GDP 0.0000000002727 0.79771 16.4384
462 4BQS ADP 0.00001368 0.52267 16.4773
463 1HE1 GDP 0.00000002143 0.55355 17.0455
464 2IS6 ADP 0.0000921 0.5031 17.0901
465 1OW3 GDP 0.00000001507 0.70052 17.0984
466 1MR3 G3D 0.0000000000253 0.82248 17.1271
467 5FG3 GDP 0.0000000000005925 0.8888 17.321
468 5UWT GNP 0.00000000162 0.77162 17.3913
469 2ZFZ ARG 0.04751 0.41002 17.7215
470 5IRC GDP 0.0000000746 0.65915 17.7419
471 3A1S GDP 0.0000002285 0.63178 17.8295
472 4D0N GDP 0.00000000174 0.72917 17.8378
473 5HPY GDP 0.000000007016 0.71684 17.8378
474 1KMQ GNP 0.00000002898 0.69953 17.9348
475 1UJ2 C5P 0.0000271 0.55678 18.254
476 1UJ2 ADP 0.00003125 0.55363 18.254
477 1TX4 ALF GDP 0.00000005726 0.51949 18.6441
478 4B47 GDP 0.0000000000002081 0.91037 18.7328
479 1X1R GDP 0.000000001464 0.77385 19.1011
480 1RYH GNP 0.000000002273 0.73273 19.2118
481 1KSH GDP 0.00000000001586 0.85542 19.3548
482 1KK8 BEF ADP 0.00004729 0.52869 19.4245
483 2FH5 GTP 0.0000000001401 0.80841 19.4595
484 4H1V GNP 0.0000002576 0.63995 19.5122
485 1TU3 GNP 0.000000000166 0.81879 19.883
486 1R2Q GNP 0.0000000002986 0.828 20
487 1F2U ATP 0.0004153 0.49648 20.1342
488 3MJH GTP 0.0000000001415 0.8223 20.2381
489 2C5L GTP 0.0000000005934 0.79381 20.5128
490 4R98 GNH 0.0000000004401 0.75774 20.6642
491 2A9K GDP 0.0000000002313 0.78966 21.9731
492 1SVI GDP 0.0000000004055 0.75416 22.0513
493 3ZIA ADP 0.000007858 0.56407 22.2222
494 3ZIA ATP 0.000007967 0.55743 22.2222
495 1J2J GTP 0.0000000003213 0.58175 24.4444
496 1W7J ADP BEF 0.0000501 0.44836 24.5033
497 1Z0K GTP 0.0000000008254 0.7771 25
498 1CXZ GSP 0.00000001573 0.70976 25.8242
499 2WJG GDP 0.000000000007051 0.80508 26.0638
500 1GP2 GDP 0.0000000002678 0.58842 28.169
501 4RD0 GDP 0.000000000001243 0.91465 28.6747
502 2QN6 GDP 0.0000000000001421 0.91824 28.9855
503 2WJH GDP 0.0000000000194 0.82803 29.5181
504 2WJH FLC 0.0000000874 0.65581 29.5181
505 2BME GNP 0.0000000008782 0.78214 36.5591
506 1Y3A GDP 0.0000000002605 0.80223 37.5
507 1KK1 GNP 0.00000000000008815 0.92809 38.7991
508 1G7C 5GP 0.000000001416 0.73345 45.9584
509 3WXM GTP 0.00000000007652 0.83582 47.1132
Pocket No.: 2; Query (leader) PDB : 4J0Q; Ligand: GDP; Similar sites found: 9
This union binding pocket(no: 2) in the query (biounit: 4j0q.bio3) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5CUQ NSC 0.04376 0.40021 1.87266
2 1PVN MZP 0.04645 0.40563 2.12766
3 2J5V PCA 0.03499 0.40157 2.45232
4 1GQY ACP 0.01439 0.40455 2.77136
5 4YNU FAD 0.04378 0.4112 5.08083
6 2O0J ADP 0.007516 0.40334 5.45455
7 2CK3 ADP 0.0001368 0.40267 6
8 3I54 CMP 0.01675 0.4013 6.4257
9 4AF0 IMP 0.01217 0.41717 11.3164
Pocket No.: 3; Query (leader) PDB : 4J0Q; Ligand: GDP; Similar sites found: 4
This union binding pocket(no: 3) in the query (biounit: 4j0q.bio4) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1ME8 RVP 0.01438 0.43008 1.84758
2 2B4D COA 0.02198 0.40094 3.50877
3 3F8K COA 0.02821 0.40016 5.625
4 2ZE7 AMP 0.003286 0.44916 7.90514
Pocket No.: 4; Query (leader) PDB : 4J0Q; Ligand: GDP; Similar sites found: 4
This union binding pocket(no: 4) in the query (biounit: 4j0q.bio2) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3E7O 35F 0.03398 0.40378 1.84758
2 2VOS ADP 0.0245 0.40021 1.84758
3 4M7V RAR 0.02592 0.42284 7.42857
4 5WRI A3P 0.0003744 0.40068 12.5
Pocket No.: 5; Query (leader) PDB : 4J0Q; Ligand: GDP; Similar sites found: 2
This union binding pocket(no: 5) in the query (biounit: 4j0q.bio5) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1YS4 NAP 0.02056 0.40565 1.9774
2 3BER AMP 0.006652 0.40418 8.43373
Feedback