Receptor
PDB id Resolution Class Description Source Keywords
4KAX 1.85 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE GRP1 PH DOMAIN IN COMPLEX WITH ARF6 HOMO SAPIENS PH DOMAIN PHOSPHOINOSITIDES PROTEIN BINDING-SIGNALING PROTCOMPLEX
Ref.: STRUCTURAL BASIS FOR MEMBRANE RECRUITMENT AND ALLOS ACTIVATION OF CYTOHESIN FAMILY ARF GTPASE EXCHANGE PROC.NATL.ACAD.SCI.USA V. 110 14213 2013
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL B:1102;
A:204;
B:1103;
B:1104;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
CIT A:203;
Invalid;
none;
submit data
192.124 C6 H8 O7 C(C(=...
K A:205;
Part of Protein;
none;
submit data
39.098 K [K+]
MG A:202;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
GTP A:201;
Valid;
none;
submit data
523.18 C10 H16 N5 O14 P3 c1nc2...
4IP B:1101;
Valid;
none;
submit data
500.075 C6 H16 O18 P4 [C@H]...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4KAX 1.85 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE GRP1 PH DOMAIN IN COMPLEX WITH ARF6 HOMO SAPIENS PH DOMAIN PHOSPHOINOSITIDES PROTEIN BINDING-SIGNALING PROTCOMPLEX
Ref.: STRUCTURAL BASIS FOR MEMBRANE RECRUITMENT AND ALLOS ACTIVATION OF CYTOHESIN FAMILY ARF GTPASE EXCHANGE PROC.NATL.ACAD.SCI.USA V. 110 14213 2013
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 4KAX - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 196 families.
1 1FHX Kd = 0.027 uM 4IP C6 H16 O18 P4 [C@H]1([C@....
2 4KAX - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 171 families.
1 1FHX Kd = 0.027 uM 4IP C6 H16 O18 P4 [C@H]1([C@....
2 4KAX - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GTP; Similar ligands found: 147
No: Ligand ECFP6 Tc MDL keys Tc
1 GTP 1 1
2 GP3 0.921053 0.973684
3 GDP 0.909091 1
4 GSP 0.853659 0.948718
5 GNH 0.82716 0.986667
6 G1R 0.819277 0.986667
7 GAV 0.811765 0.961039
8 GNP 0.809524 0.973684
9 GCP 0.797619 0.973684
10 5GP 0.797468 0.986486
11 G 0.797468 0.986486
12 GMV 0.764706 0.973684
13 G2R 0.764045 0.961039
14 G5P 0.755319 0.973684
15 GTG 0.752688 0.936709
16 G2P 0.747126 0.961039
17 G3A 0.744681 0.973684
18 GDD 0.741935 0.961039
19 GKE 0.741935 0.961039
20 GDC 0.741935 0.961039
21 0O2 0.736264 0.986486
22 GP2 0.729412 0.961039
23 6CK 0.726316 0.936709
24 Y9Z 0.723404 0.902439
25 GPG 0.717391 0.961039
26 GFB 0.715789 0.961039
27 GDR 0.715789 0.961039
28 GDP MG 0.712644 0.923077
29 GDP BEF 0.704545 0.9
30 GPD 0.704082 0.925
31 JB2 0.693878 0.961039
32 GKD 0.693878 0.961039
33 GCP G 0.692308 0.935065
34 GDX 0.686869 0.973684
35 ALF 5GP 0.685393 0.888889
36 GTP MG 0.681319 0.923077
37 BEF GDP 0.681319 0.888889
38 GH3 0.681319 0.973333
39 YGP 0.677083 0.901235
40 G3D 0.67033 0.986486
41 GDP AF3 0.659574 0.888889
42 GDP ALF 0.659574 0.888889
43 DGT 0.659341 0.923077
44 GMP 0.658228 0.88
45 G4P 0.655914 0.986486
46 JB3 0.653846 0.948718
47 NGD 0.647619 0.961039
48 CAG 0.642202 0.880952
49 2MD 0.62963 0.891566
50 G G 0.622449 0.935065
51 MGP 0.619565 0.961039
52 U2G 0.616822 0.936709
53 6G0 0.612903 0.961039
54 MGD 0.612613 0.891566
55 TPG 0.608696 0.840909
56 CG2 0.605505 0.936709
57 GDP 7MG 0.601942 0.911392
58 FEG 0.601852 0.879518
59 ZGP 0.59633 0.869048
60 MD1 0.591304 0.891566
61 PGD 0.591304 0.925
62 3GP 0.590909 0.946667
63 GPX 0.581633 0.946667
64 DGI 0.580645 0.923077
65 IDP 0.576087 0.972973
66 DBG 0.567797 0.948718
67 FE9 0.555556 0.776596
68 2GP 0.555556 0.96
69 G4M 0.547619 0.880952
70 BGO 0.544643 0.924051
71 I2C FE2 CMO CMO 0.538462 0.808989
72 ATP 0.537634 0.92
73 G1G 0.533898 0.925
74 AQP 0.531915 0.92
75 5FA 0.531915 0.92
76 G A A A 0.525862 0.923077
77 U A G G 0.521368 0.935065
78 01G 0.518868 0.902439
79 ITT 0.510638 0.868421
80 P2G 0.510638 0.883117
81 GGM 0.504274 0.901235
82 G1R G1R 0.504065 0.924051
83 DGP 0.5 0.910256
84 PGD O 0.5 0.850575
85 MGO 0.5 0.864198
86 P1G 0.5 0.871795
87 DG 0.5 0.910256
88 GTA 0.495495 0.936709
89 B4P 0.489362 0.894737
90 AP5 0.489362 0.894737
91 IMP 0.489362 0.959459
92 7DT 0.484536 0.906667
93 G G U 0.482143 0.935065
94 GPC 0.479339 0.879518
95 G C 0.478992 0.9
96 BA3 0.478723 0.894737
97 ADP 0.473684 0.92
98 G2Q 0.471698 0.961039
99 G7M 0.46875 0.948052
100 25L 0.458716 0.907895
101 A2D 0.457447 0.894737
102 RGT 0.45045 0.909091
103 AGS 0.45 0.873418
104 SAP 0.45 0.873418
105 SGP 0.44898 0.82716
106 U G A 0.448529 0.888889
107 A4P 0.445378 0.869048
108 G G G RPC 0.442623 0.875
109 ACQ 0.441176 0.896104
110 ANP 0.441176 0.896104
111 8GT 0.441176 0.875
112 APC G U 0.44 0.886076
113 G U34 0.438017 0.888889
114 6AD 0.436893 0.841463
115 G G G C 0.433071 0.9125
116 UP5 0.432203 0.873418
117 35G 0.431373 0.933333
118 C2E 0.431373 0.921053
119 PCG 0.431373 0.933333
120 A G C C 0.429688 0.911392
121 5GP 5GP 0.427184 0.883117
122 TAT 0.427184 0.884615
123 APR 0.425743 0.894737
124 AR6 0.425743 0.894737
125 AN2 0.424242 0.907895
126 7DD 0.424242 0.906667
127 DG DG 0.423423 0.865854
128 AD9 0.421569 0.896104
129 M33 0.42 0.883117
130 7D4 0.42 0.835443
131 UCG 0.419847 0.911392
132 H6Y 0.419048 0.946667
133 G C C C 0.416667 0.924051
134 ACP 0.415842 0.896104
135 T5A 0.414634 0.802326
136 MGQ 0.412844 0.935897
137 ADQ 0.412844 0.871795
138 A1R 0.412844 0.839506
139 MGT 0.411215 0.823529
140 A G U 0.410072 0.888889
141 93A 0.41 0.833333
142 A22 0.407407 0.907895
143 CA0 0.405941 0.896104
144 ATF 0.40566 0.884615
145 AGO 0.404762 0.888889
146 MGV 0.401786 0.890244
147 CGP 0.4 0.86747
Ligand no: 2; Ligand: 4IP; Similar ligands found: 15
No: Ligand ECFP6 Tc MDL keys Tc
1 4IP 1 1
2 I3P 0.724138 0.966667
3 I3S 0.724138 0.966667
4 5MY 0.714286 0.965517
5 5IP 0.714286 0.965517
6 IP5 0.714286 0.965517
7 I5P 0.714286 0.965517
8 I4P 0.653846 0.965517
9 I0P 0.62069 0.933333
10 ITP 0.6 0.966667
11 2IP 0.571429 0.966667
12 IHP 0.538462 0.965517
13 I6P 0.538462 0.965517
14 IP2 0.533333 0.966667
15 I4D 0.516129 0.933333
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4KAX; Ligand: 4IP; Similar sites found: 37
This union binding pocket(no: 1) in the query (biounit: 4kax.bio1) has 14 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1CLU DBG 0.04727 0.40984 None
2 1JJE BYS 0.01149 0.41964 3.10559
3 1SLT NDG GAL 0.008667 0.40465 3.73134
4 2W5P CL8 0.01313 0.4 4.02685
5 4G1V FAD 0.0257 0.41181 4.73373
6 5C03 AGS 0.01502 0.41001 4.73373
7 5EOU ATP 0.0111 0.42214 4.96894
8 3OZV FAD 0.02842 0.42472 5.32544
9 3OZV ECN 0.04881 0.41461 5.32544
10 5LRT ADP 0.03113 0.4034 5.59006
11 2OWZ F6P 0.02136 0.40223 5.59006
12 4M0F 1YK 0.03394 0.40891 7.45342
13 5IXJ THR 0.0349 0.40711 7.45342
14 5FLJ QUE 0.01217 0.42007 7.69231
15 2EB5 OXL 0.01348 0.40419 7.69231
16 3NOJ PYR 0.005164 0.4257 7.98319
17 5N87 N66 0.03609 0.41069 8.07453
18 5KVM THR TYR PHE ALA VAL LEU MET VAL SER 0.04945 0.40003 8.42105
19 3E9I XAH 0.0307 0.40891 8.69565
20 1BGV GLU 0.01374 0.402 8.69565
21 3O0G 3O0 0.02137 0.4003 8.72483
22 4D2S DYK 0.01639 0.40191 8.87574
23 1W1G 4PT 0.000006414 0.55817 9.93377
24 2CUN 3PG 0.0251 0.4042 9.93789
25 3SJK LYS PRO VAL LEU ARG THR ALA 0.002405 0.44232 10.0592
26 4BVA T3 0.005323 0.4601 10.559
27 5A0R ACE GLU VAL ASN PRO 0.0364 0.40247 11.1801
28 5DEY 59T 0.01693 0.42963 13.0435
29 1B55 4IP 0.00002695 0.47353 16.1491
30 3FV3 IVA VAL VAL STA ALA STA 0.03455 0.40368 16.1491
31 5GXU FAD 0.02284 0.41454 18.3432
32 1LSH PLD 0.0218 0.41687 19.5266
33 5A5W GUO 0.04563 0.40982 19.8758
34 5UKL SIX 0.02459 0.41153 23.6025
35 1FAO 4IP 0.000000001591 0.7343 31.746
36 1UPR 4IP 0.00002619 0.52857 34.9594
37 1UNQ 4IP 0.0000219 0.53926 44
Pocket No.: 2; Query (leader) PDB : 4KAX; Ligand: GTP; Similar sites found: 453
This union binding pocket(no: 2) in the query (biounit: 4kax.bio1) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1CLU DBG 0.00000003937 0.6569 None
2 4QRH 0O2 0.003761 0.40321 2.48447
3 2C5L GTP 0.00000000003543 0.68088 2.5641
4 4M7V NAP 0.006123 0.41316 2.95858
5 1FP6 ADP 0.0001322 0.48915 3.10559
6 4QM7 GTP 0.00005157 0.52694 3.5503
7 3BOS CDP 0.00007639 0.51863 3.5503
8 5L3W GDP 0.000008894 0.4832 3.5503
9 3QKT ANP 0.0005548 0.42837 3.5503
10 2W58 ADP 0.000001791 0.64281 3.72671
11 3DC4 ADP 0.000001596 0.6193 3.72671
12 1TQ4 GDP 0.0000001334 0.60136 3.72671
13 2ZFI ADP 0.000006613 0.57038 3.72671
14 1BO4 COA 0.003433 0.43812 3.72671
15 3BER AMP 0.01062 0.41415 3.72671
16 2XT3 ADP 0.000002511 0.62339 4.14201
17 4GOX A3P 0.001211 0.42245 4.14201
18 1SKQ GDP 0.00000000003143 0.84458 4.34783
19 2GJ8 ALF GDP 0.0000000001165 0.66085 4.34783
20 2NCD ADP 0.00001069 0.58378 4.34783
21 3DKP ADP 0.0003483 0.48654 4.34783
22 3ZQ6 ADP ALF 0.00003023 0.463 4.34783
23 2BEK ATP 0.0006398 0.44074 4.34783
24 4O48 ASP 0.01402 0.41918 4.34783
25 3B5J 12D 0.00001995 0.56304 4.73373
26 1XP8 AGS 0.00004908 0.53524 4.73373
27 1XKV ATP 0.00009334 0.5018 4.73373
28 2ZPA ADP 0.0005599 0.43081 4.73373
29 2F5X ASP 0.02353 0.40757 4.73373
30 1VHT BA3 0.0006378 0.46305 4.96894
31 4PJ3 ANP 0.006115 0.41354 4.96894
32 2OG2 MLI 0.000002381 0.61378 5.32544
33 2FAH GDP 0.0004077 0.46696 5.32544
34 1YTM ATP 0.0003232 0.45739 5.32544
35 2C9O ADP 0.0005122 0.44888 5.32544
36 4IOK XPO 0.0004254 0.43503 5.32544
37 4FRZ ADP 0.00001026 0.42679 5.32544
38 3BFX A3P 0.002441 0.42372 5.32544
39 4IOK ADP 0.0005439 0.41409 5.32544
40 2QN6 GDP 0.00000000002652 0.84826 5.59006
41 4RD0 GDP 0.000000000001608 0.79916 5.59006
42 1NVV GNP 0.00000000004055 0.67845 5.59006
43 1NVU GTP 0.00000000004831 0.67579 5.59006
44 3A4M ADP 0.000002094 0.61324 5.59006
45 3KTA AP5 0.0003678 0.46899 5.59006
46 1KO8 6PG 0.0005185 0.43245 5.59006
47 1D2N ANP 0.002047 0.42327 5.59006
48 4FCW ADP 0.0003113 0.42021 5.59006
49 1NHX PEP 0.0119 0.41106 5.59006
50 1NHX FTB 0.01512 0.40724 5.59006
51 2ZE7 DST 0.008151 0.40097 5.59006
52 2ZE7 AMP 0.007805 0.40028 5.59006
53 2FFQ GSP 0.000000000001951 0.81092 5.91716
54 1YZQ GNP 0.000000000002007 0.72265 5.91716
55 4LC1 GDP 0.00000000842 0.71136 5.91716
56 1WQ1 AF3 0.000000185 0.68192 5.91716
57 3B9Q MLI 0.000001449 0.63586 5.91716
58 1WQ1 GDP 0.00000004376 0.60112 5.91716
59 1OXV ANP 0.00001236 0.56515 5.91716
60 4ZG4 VO4 ADP 0.000001509 0.55285 5.91716
61 4IDN GNP 0.00002203 0.50172 5.91716
62 1Z6T ADP 0.0004359 0.46082 5.91716
63 4WOP CTP 0.0002988 0.44884 5.91716
64 1UKZ ADP 0.001349 0.44319 5.91716
65 4ZNL BEF ADP 0.0001476 0.42578 5.91716
66 5E5U MLI 0.01022 0.41753 5.91716
67 1F2U ATP 0.0006971 0.41234 6.04027
68 1D2E GDP 0.000000004379 0.69242 6.21118
69 4LPS GDP 0.00000006296 0.65861 6.21118
70 2DPY ADP 0.0005556 0.48894 6.21118
71 2IS6 ADP 0.0003712 0.48519 6.21118
72 1RRC ADP 0.000002218 0.42534 6.21118
73 3QXC ATP 0.0006939 0.4156 6.21118
74 2WIC GNP 0.0000000001287 0.78644 6.50888
75 1G7C 5GP 0.00000002251 0.69056 6.50888
76 1XMV ADP 0.00004716 0.522 6.50888
77 1P9B GDP 0.00002825 0.51357 6.50888
78 1QF5 RPL 0.002956 0.47339 6.50888
79 4MKG AP5 0.0005757 0.46712 6.50888
80 2VVG ADP 0.000000521 0.43703 6.50888
81 1P9B HDA 0.01393 0.41918 6.50888
82 2J5V PCA 0.0238 0.40512 6.50888
83 1GXU 2HP 0.0006617 0.47402 6.59341
84 4KFU ACP 0.000003361 0.61004 6.60377
85 2D2F ADP 0.00003999 0.56414 6.8
86 4B47 GDP 0.00000000002543 0.84918 6.8323
87 1JWY GDP 0.0000001523 0.62249 6.8323
88 3EC1 GDP 0.000000002805 0.59579 6.8323
89 1JJV ATP 0.00003428 0.55557 6.8323
90 1JWY ADP 0.000015 0.54565 6.8323
91 4HSE ADP 0.0002009 0.49209 6.8323
92 1YRB GDP 0.000000003465 0.69703 7.10059
93 5HCN GCP 0.00000001842 0.68398 7.10059
94 3NHB ADP 0.000004513 0.60502 7.10059
95 2WHX ADP 0.0000108 0.58468 7.10059
96 2C04 GCP 0.000007628 0.5388 7.10059
97 4NON GDP 0.0000001539 0.53853 7.10059
98 4TTQ ATP 0.00007192 0.51991 7.10059
99 2B8W ALF 5GP 0.000004967 0.51 7.10059
100 2JLR ANP 0.0001131 0.49223 7.10059
101 1G41 ADP 0.0002602 0.48113 7.10059
102 5H56 ADP 0.0003661 0.46346 7.10059
103 5H56 TYD 0.0003661 0.46346 7.10059
104 3COB ADP 0.000002433 0.4349 7.10059
105 5MUA GAL 0.0227 0.40188 7.10059
106 4MKF AP5 0.0007845 0.46227 7.37327
107 3BFV ADP 0.00000378 0.58221 7.45342
108 3ZFD ANP 0.0000001751 0.54027 7.45342
109 5LB3 ADP 0.000268 0.49842 7.45342
110 4TMK T5A 0.004821 0.41895 7.45342
111 4PX9 ADP 0.0002463 0.40573 7.45342
112 4R98 GNH 0.00000001414 0.56594 7.69231
113 5L3R GCP 0.0000004823 0.54872 7.69231
114 3FWY ADP 0.00004111 0.50634 7.69231
115 2VF7 ADP 0.0002055 0.49162 7.69231
116 4QOS ADP 0.0005576 0.46576 7.69231
117 1FNN ADP 0.0004513 0.45558 7.69231
118 2CHG ANP 0.0006539 0.453 7.69231
119 4KBF AMP 0.002398 0.45086 7.69231
120 3QF7 ANP 0.000361 0.43798 7.69231
121 3IUY AMP 0.009204 0.4172 7.69231
122 5L3V GDP 0.0000007138 0.60004 8.07453
123 5L3S GNP 0.000001997 0.55022 8.07453
124 4PFO ADP 0.00003626 0.49923 8.07453
125 2VB6 ADP BEF 0.00003 0.49842 8.07453
126 4R2I ANP 0.001243 0.47101 8.07453
127 3DZD ADP 0.0007297 0.45549 8.07453
128 1NJF AGS 0.0005179 0.44456 8.07453
129 1NJF ADP 0.0003279 0.44055 8.07453
130 1BG2 ADP 0.000000594 0.43294 8.07453
131 1UJ2 C5P 0.0003341 0.42301 8.07453
132 1UJ2 ADP 0.00061 0.41313 8.07453
133 2HK9 ATR 0.01177 0.41198 8.07453
134 1SES AMP 0.01813 0.40681 8.07453
135 1UH4 GLC GLC GLC GLC GLC 0.03017 0.40217 8.07453
136 1DAR GDP 0.0000000002182 0.78862 8.28402
137 1JJ7 ADP 0.0000004465 0.67865 8.28402
138 2HF9 GSP 0.00000005458 0.63402 8.28402
139 5FG3 GDP 0.00000000009605 0.61138 8.28402
140 4HI0 GDP 0.0000001235 0.60279 8.28402
141 4BQS ADP 0.00002749 0.54025 8.28402
142 4BQS K2Q 0.0006219 0.46063 8.28402
143 4YS0 ADP 0.002433 0.42766 8.28402
144 3KUD GDP 0.0000000072 0.65529 8.64198
145 1V8K ANP 0.000001509 0.60163 8.69565
146 4WZ6 ATP 0.000006768 0.59548 8.69565
147 2QEN ADP 0.00004669 0.50388 8.69565
148 4LJ9 ACP 0.0005974 0.47513 8.69565
149 5I34 GDP 0.000009445 0.47452 8.69565
150 5SWI BMA 0.02625 0.41087 8.69565
151 3W5J GDP 0.00000001394 0.74134 8.87574
152 1WF3 GNP 0.0000000003743 0.71366 8.87574
153 1M7G AV2 0.00000078 0.62508 8.87574
154 3PQC GDP 0.00000093 0.59471 8.87574
155 2D7D ADP 0.003562 0.43733 8.87574
156 1M7G ADP 0.00007848 0.43271 8.87574
157 1M7G ADX 0.00005615 0.42591 8.87574
158 3CV2 OXL 0.0255 0.40703 8.87574
159 2X7I CIT 0.01933 0.4014 8.87574
160 3P4X ADP 0.00002867 0.43435 8.95884
161 3DDC GNP 0.00000000006647 0.67107 9.20245
162 3E70 GDP 0.000001295 0.5962 9.31677
163 1IN4 ADP 0.0006111 0.44986 9.31677
164 5GJC ATP 0.00002573 0.44146 9.31677
165 1W5T ADP 0.0043 0.41666 9.31677
166 1W5T ANP 0.003161 0.41524 9.31677
167 1T5C ADP 0.000001302 0.64306 9.46746
168 1G6O ADP 0.00003517 0.52148 9.46746
169 4IEE AGS 0.0003596 0.49204 9.46746
170 3B7G ANP 0.001012 0.4587 9.46746
171 1CR1 TTP 0.0007943 0.43112 9.46746
172 1F9V ADP 0.000009774 0.42791 9.46746
173 1KK1 GNP 0.00000000003848 0.84019 9.93789
174 3WXM GTP 0.0000000000402 0.75163 9.93789
175 4AG5 ADP 0.000006284 0.59615 9.93789
176 5I0H ADP BEF 0.0000003172 0.56928 9.93789
177 3TBK ANP 0.00216 0.45868 9.93789
178 3RC3 ANP 0.00269 0.44836 9.93789
179 1NY5 ADP 0.001862 0.43282 9.93789
180 5KSP GDP 0.0000009068 0.60356 10.0592
181 5KSZ GCP 0.000004001 0.56529 10.0592
182 5KUT GDP 0.0000002417 0.5269 10.0592
183 4Q1A UDP 0.001652 0.49791 10.0592
184 4Q1A 2XZ 0.001652 0.49791 10.0592
185 4R43 GDP 0.0002107 0.49717 10.0592
186 1W0J ADP 0.00008138 0.45064 10.0592
187 2Y65 ADP 0.000002488 0.43258 10.0592
188 4U00 ADP 0.000001449 0.41813 10.0592
189 1W0J ADP BEF 0.001484 0.41496 10.0592
190 3R7F CP 0.01827 0.41354 10.0592
191 3BD9 A3P 0.01406 0.40426 10.0592
192 4IHQ ADP 0.0002028 0.50447 10.559
193 2Q2Y ADP 0.000715 0.46291 10.559
194 2Q2Y MKR 0.0007606 0.46053 10.559
195 5X40 ACP 0.0002649 0.45875 10.559
196 1XEX ATP 0.001778 0.40233 10.559
197 1W7J ADP BEF 0.00001044 0.53276 10.596
198 2AWN ADP 0.0000002953 0.69769 10.6509
199 4P4T GDP 0.0000005282 0.58293 10.6509
200 2GDJ ANP 0.000135 0.50659 10.6509
201 1OYY AGS 0.002609 0.44393 10.6509
202 5TSH ANP 0.00003672 0.43881 10.6509
203 3FYH ADP 0.001262 0.41403 10.6509
204 4NZ6 DGL 0.02762 0.403 10.6509
205 5TSH ADP 0.0001028 0.40223 10.6509
206 1B0U ATP 0.0005916 0.45962 11.0687
207 1SVI GDP 0.00000002488 0.69982 11.1801
208 1SQ5 ADP 0.00007141 0.51344 11.1801
209 1G3Q ADP 0.00003148 0.53034 11.2426
210 1ION ADP 0.00007252 0.50689 11.2426
211 1IHU AF3 0.0001875 0.46296 11.2426
212 1IHU ADP 0.0001892 0.45449 11.2426
213 2UZI GTP 0.00000000008452 0.73795 11.4035
214 1LVG ADP 0.0000002648 0.47984 11.6162
215 4CVN ADP 0.00002188 0.56098 11.6788
216 2RCN GDP 0.0000000002261 0.78786 11.8012
217 5BQ5 ADP BEF 0.0001386 0.49383 11.8012
218 1F5N GNP 0.00000507 0.49218 11.8012
219 1R6B ADP 0.0002502 0.48756 11.8012
220 3KJI ADP 0.00005653 0.45957 11.8012
221 2IXE ATP 0.0003325 0.45259 11.8012
222 5MZN ADP 0.005148 0.43931 11.8012
223 2HT6 GDP 0.000000000008468 0.87303 11.8343
224 1MKY GDP 0.00000000005062 0.81952 11.8343
225 2CJW GDP 0.0000000001108 0.80295 11.8343
226 2NGR AF3 0.0000000926 0.68269 11.8343
227 2NGR GDP 0.00000005287 0.66222 11.8343
228 1GRN AF3 0.0000002563 0.66002 11.8343
229 1A4R GNH 0.00000001486 0.65909 11.8343
230 1A4R GDP 0.000000009528 0.65867 11.8343
231 1GRN GDP 0.0000001447 0.61523 11.8343
232 5N69 ADP 0.00002196 0.52453 11.8343
233 3IIJ ADP 0.00001015 0.56131 12.2222
234 4K81 GTP 0.0000000003516 0.63286 12.4224
235 4ITR GDP 0.000001013 0.57064 12.4224
236 1U0J ADP 0.0004773 0.48589 12.4224
237 1X1R GDP 0.000000002894 0.61097 12.426
238 3FVQ ATP 0.0003294 0.45704 12.426
239 4D81 ADP 0.0003506 0.42606 12.426
240 4OI4 ATP 0.001052 0.42448 12.426
241 1NST A3P 0.007011 0.40722 12.426
242 1APZ ASP 0.009255 0.4262 12.963
243 3VX3 ADP 0.0002444 0.46715 13.0178
244 1WRA PC 0.03331 0.407 13.0435
245 4WZA ADP 0.00006312 0.52974 13.6095
246 4WZA ACP 0.00006312 0.52974 13.6095
247 2OFW ADX 0.00006907 0.50697 13.6095
248 2PL3 ADP 0.0003596 0.49204 13.6095
249 4A4Z ANP 0.001768 0.45216 13.6095
250 2ZJ5 ADP 0.02557 0.40622 13.6095
251 1NN5 ANP 0.0002988 0.40114 13.6095
252 4NCN GTP 0.000000000008363 0.75056 13.6646
253 3H4S ADP 0.000003377 0.42706 14.0741
254 1JI0 ATP 0.000004612 0.59566 14.1667
255 3DEF GDP 0.000006521 0.54846 14.2012
256 4XTR ATP 0.00008172 0.48017 14.2012
257 4XVU ATP 0.00009281 0.47785 14.2012
258 3ZS9 ADP ALF 0.00003306 0.46197 14.2012
259 4XTR ADP 0.000112 0.4594 14.2012
260 2WOJ ADP ALF 0.00004255 0.45833 14.2012
261 2ZR9 DTP 0.000028 0.53986 14.2857
262 2GWH A3P 0.008826 0.40276 14.2857
263 2PEZ GGZ 0.00006934 0.49802 14.5251
264 2PEZ DAT 0.00006934 0.49802 14.5251
265 1L2T ATP 0.0006247 0.42624 14.7929
266 1OFH ADP 0.000327 0.47652 14.9068
267 1CM0 COA 0.01416 0.40041 14.9068
268 1G7S GDP 0.0000000002086 0.77646 15.528
269 3RLF ANP 0.0004117 0.4407 15.528
270 3H86 AP5 0.000694 0.4572 15.625
271 3ZIA ATP 0.00005779 0.5178 15.942
272 3ZIA ADP 0.0001287 0.48969 15.942
273 5M04 GDP 0.00000000001579 0.63438 15.9763
274 2V7Q ATP 0.00005527 0.51236 16
275 2V7Q ADP 0.0004638 0.48048 16
276 2CK3 ANP 0.001785 0.42963 16
277 2CK3 ADP 0.002493 0.40974 16
278 1LFD GNP 0.00000000004258 0.69157 16.092
279 1QHG ATP 0.01173 0.40064 16.1491
280 5TAR GDP 0.000000006387 0.68499 16.568
281 5O2T GSP 0.0000000001349 0.66091 16.568
282 5TB5 GDP 0.000000002944 0.60466 16.568
283 1PUJ GNP 0.0000000001316 0.76148 17.1598
284 1K6M AGS 0.0008934 0.42715 17.1598
285 1QHH ATP 0.01561 0.40208 17.3913
286 2IYL GDP 0.00000192 0.59653 17.7515
287 2XAU ADP 0.0004087 0.47202 18.0124
288 3TW1 AHN 0.02733 0.40386 18.0124
289 1YQT ADP 0.00002194 0.56754 18.3432
290 2BIF ANP 0.0003931 0.46663 18.3432
291 2BIF SIN 0.0007033 0.46663 18.3432
292 4U5X GNP 0.000000001634 0.69193 18.9349
293 2J0V GDP 0.00000006212 0.55036 18.9349
294 4YMU ATP 0.00002666 0.54848 19.5266
295 1G6H ADP 0.0000005154 0.67497 19.8758
296 2KIN ADP 0.000001054 0.42694 20
297 2C77 GNP 0.000000000000752 0.82463 20.1183
298 2C78 GNP 0.000000000001994 0.79527 20.1183
299 2WKQ GTP 0.000000002276 0.65402 20.1183
300 4DID GDP 0.00000009429 0.65028 20.1183
301 2CE7 ADP 0.0001706 0.43087 20.7101
302 2GK6 ADP 0.005548 0.43764 21.3018
303 1G8S MET 0.01142 0.42408 21.3018
304 1ZUI SKM 0.0001026 0.40209 21.4286
305 4P32 ADP 0.0006258 0.44114 21.7391
306 1X6V ADP 0.00006207 0.43756 21.7391
307 1M7B GTP 0.000000002267 0.67663 21.8935
308 2XTZ GSP 0.000000000001167 0.74774 22.4852
309 1CS4 GSP 0.0000000000005259 0.72725 22.4852
310 1AZT GSP 0.0000000000007476 0.70717 22.4852
311 1GOJ ADP 0.0000003009 0.68041 22.4852
312 2ZEJ GDP 0.00000005241 0.56245 22.4852
313 5UWP GNP 0.000000000006144 0.79304 23.0769
314 5UWU GNP 0.000000000005828 0.79067 23.0769
315 5UWR GNP 0.000000000005857 0.79058 23.0769
316 5UWT GNP 0.000000000005946 0.7903 23.0769
317 5UWI GNP 0.000000000006081 0.78988 23.0769
318 5DI9 GNP 0.000000000008641 0.7867 23.0769
319 3CH5 GDP 0.0000000001541 0.78271 23.0769
320 3GJ3 GDP 0.0000000006129 0.76678 23.0769
321 3GJ0 GDP 0.000000001113 0.75416 23.0769
322 5UWQ GNP 0.000000000005079 0.70858 23.0769
323 5UWW GNP 0.000000000005755 0.70676 23.0769
324 5DIF GNP 0.000000000006203 0.70565 23.0769
325 5UWJ GNP 0.000000000006432 0.70508 23.0769
326 5UWO GNP 0.000000000006661 0.70462 23.0769
327 5DHF GNP 0.000000000007247 0.70343 23.0769
328 1IBR GNP 0.00000000001269 0.69541 23.0769
329 4HAT GNP 0.000000000006226 0.69072 23.0769
330 5UWS GNP 0.000000000008919 0.68575 23.0769
331 5BXQ GDP 0.0000000002054 0.63387 23.0769
332 3GJ8 GDP 0.0000000001725 0.78039 23.6686
333 3GJ5 GDP 0.0000000002581 0.77206 23.6686
334 3GJ7 GDP 0.000000001079 0.75482 23.6686
335 3GJ4 GDP 0.000000001218 0.75226 23.6686
336 1KMQ GNP 0.000000000172 0.69888 23.6686
337 2GCN GDP 0.00000006211 0.60799 24.2604
338 3A1S GDP 0.000001795 0.58946 24.4186
339 3M1I GTP 0.000000000005868 0.79054 24.8521
340 4H1V GNP 0.000001506 0.57008 24.8521
341 3MD0 GDP 0.00000000009395 0.82083 25.4438
342 3TK1 GDP 0.0000000005188 0.79816 25.4438
343 3REF GDP 0.00000001841 0.63 25.4438
344 1D8T GDP 0.00000000006041 0.81578 25.4658
345 2BVN GNP 0.00000000001026 0.81177 25.4658
346 2HCJ GDP 0.0000000000297 0.62607 25.4658
347 3Q72 GNP 0.0000000002932 0.79614 25.9036
348 1TAD GDP 0.000000000001722 0.6967 26.0355
349 1TAD ALF 0.000000000001722 0.6967 26.0355
350 3UIE ANP 0.0000379 0.51997 26.087
351 1NRJ GTP 0.000000000002837 0.8001 26.1468
352 1E96 GTP 0.0000000006518 0.64931 26.5625
353 3T12 GDP ALF 0.00000000000253 0.79096 26.6272
354 3T1O GDP 0.0000000002676 0.64101 26.6272
355 1GOT GDP 0.00000001346 0.63568 26.6272
356 1B7T ADP 0.0000639 0.50944 26.9231
357 1KAO GDP 0.00000002401 0.64985 26.9461
358 5UQW GDP 0.000000001946 0.67716 27.2189
359 5UWH GNP 0.000000000006545 0.70479 27.2727
360 1KK8 BEF ADP 0.00001249 0.52929 27.2727
361 1FQJ ALF 0.000000009451 0.74345 27.8107
362 1FQK ALF 0.00000003476 0.72095 27.8107
363 1FQJ GDP 0.0000000003062 0.68671 27.8107
364 1FQK GDP 0.0000000003862 0.68282 27.8107
365 1GUA GNP 0.00000000003963 0.67869 28.1437
366 4HDO GNP 0.00000000004736 0.67629 28.1437
367 1BH2 GSP 0.000000000001788 0.69599 28.4024
368 1XTQ GDP 0.0000000008831 0.68838 28.4024
369 2OM2 GDP 0.000000005322 0.66087 28.4024
370 5KDO GDP 0.000000006004 0.65864 28.4024
371 1Y3A GDP 0.000000003216 0.64602 28.4024
372 1GP2 GDP 0.00000001277 0.62195 28.4024
373 4DSU GDP 0.000000001711 0.61849 28.4024
374 3T5G GDP 0.000000002533 0.60814 28.4024
375 1U8Z GDP 0.000000006292 0.63501 28.5714
376 5UFQ GNP 0.000000001407 0.68619 28.9157
377 1SVK ALF GDP 0.000000000001508 0.82577 28.9941
378 3Q85 GNP 0.0000000000899 0.80737 29.5858
379 2ODE ALF GDP 0.0000000000006836 0.8373 30.1775
380 1VG8 GNP 0.00000000000386 0.79829 30.1775
381 4DCT GDP 0.000000002622 0.72422 30.1775
382 1CXZ GSP 0.0000000001951 0.71231 30.1775
383 3CX8 GSP 0.000000000001082 0.70162 30.1775
384 1TX4 ALF GDP 0.000000001023 0.6682 30.1775
385 3AB3 GDP 0.000000002429 0.65496 30.1775
386 1VG0 GDP 0.000000005898 0.60637 30.1775
387 5XCO GDP 0.00000001075 0.59912 30.1775
388 5HPY GDP 0.000000131 0.56978 30.1775
389 1OW3 GDP 0.000000131 0.56959 30.1775
390 5IRC GDP 0.0000002308 0.54369 30.1775
391 1Z0F GDP 0.000000001061 0.74288 30.7692
392 1VG1 GDP 0.0000000002796 0.62408 30.7692
393 1VG9 GDP 0.00000000105 0.60865 30.7692
394 2XTN GTP 0.000004011 0.52313 30.7692
395 2A5J GDP 0.000000002424 0.71465 31.3609
396 2GCO GNP 0.000000001642 0.70155 31.3609
397 3SBD GNP 0.0000000003828 0.65675 31.3609
398 1S8F GDP 0.0000000006392 0.62204 31.3609
399 4D0N GDP 0.00000001531 0.55821 31.677
400 2WJH GDP 0.000000001118 0.61182 31.9277
401 2WJH FLC 0.0000003768 0.53189 31.9277
402 2WJG GDP 0.0000000005042 0.77091 31.9527
403 4C4P GNP 0.00000000003211 0.75909 31.9527
404 2BME GNP 0.000000000001288 0.74701 31.9527
405 2W2X GSP 0.0000000006692 0.69918 31.9527
406 1DS6 GDP 0.00000002114 0.6919 31.9527
407 1OIV GDP 0.000000008985 0.65206 31.9527
408 1WA5 GTP 0.00000000001912 0.6373 31.9527
409 3RWO GDP 0.000000002725 0.62266 31.9527
410 2F9L GDP 0.00000002968 0.60789 31.9527
411 2D7C GTP 0.00000000002764 0.6982 32.3353
412 1Z0K GTP 0.000000000002673 0.77105 32.5444
413 1OIX GDP 0.000000000217 0.7206 32.5444
414 1MH1 GNP 0.00000000026 0.7204 32.5444
415 2HV8 GTP 0.0000000002752 0.71622 32.5444
416 2FJU GSP 0.0000000009112 0.69347 32.5444
417 1I4D GDP 0.00000005973 0.68082 32.5444
418 1G16 GDP 0.0000001825 0.58849 32.5444
419 5CK5 GDP 0.000000001766 0.57687 32.5444
420 1HE1 AF3 0.00001505 0.56932 32.5444
421 1HE1 GDP 0.0000007988 0.56829 32.5444
422 1G4U GDP 0.000001193 0.56756 32.5444
423 1G4U AF3 0.00008887 0.53534 32.5444
424 1GWN GTP 0.000000001416 0.66703 33.1361
425 2QZ4 ADP 0.00009439 0.50157 33.1361
426 1Z2A GDP 0.00000001675 0.61744 33.3333
427 1Z08 GNP 0.00000001163 0.62473 33.7278
428 1H65 GDP 0.00009191 0.47586 33.7278
429 1TU3 GNP 0.000000000008706 0.71677 34.9112
430 1R2Q GNP 0.000000000005091 0.62362 34.9112
431 2A9K GDP 0.00000001173 0.60644 34.9112
432 1YVD GNP 0.000000000006664 0.72235 35.503
433 1KY3 GDP 0.0000000141 0.66938 35.503
434 1ZC3 GNP 0.000000000231 0.6501 35.503
435 5HR5 ADP 0.0002312 0.43863 35.503
436 3MJH GTP 0.000000000002957 0.73475 35.7143
437 1RYH GNP 0.00000000107 0.73114 36.0947
438 1Z0J GTP 0.000000000002133 0.7239 36.0947
439 3BC1 GNP 0.00000000001874 0.70379 36.0947
440 1YZN GNP 0.00000000001836 0.69031 36.0947
441 1NF3 GNP 0.000000001149 0.64026 36.0947
442 2BCG GDP 0.00000002557 0.64005 36.0947
443 3RAB GNP 0.0000000000166 0.76791 36.6864
444 1D5C GDP 0.000000003646 0.68617 37.037
445 3QBT GNP 0.000000000001385 0.74607 37.2781
446 2FH5 GTP 0.000000000003334 0.79712 37.8698
447 2G77 GDP 0.00000000009798 0.75588 39.645
448 2G77 AF3 0.0000002121 0.67293 39.645
449 1Z0A GDP 0.000000001395 0.7258 40.2367
450 1Z06 GNP 0.000000000005085 0.74241 40.8284
451 1EK0 GNP 0.000000000004913 0.72535 41.4201
452 1M2O GNP 0.000000000002169 0.80538 47.3373
453 1F6B GDP 0.00000000005304 0.80473 47.3373
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