Receptor
PDB id Resolution Class Description Source Keywords
4KVG 1.65 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF RIAM RA-PH DOMAINS IN COMPLEX WITH GTP HOMO SAPIENS RAS-RELATED PROTEIN UBIQUITIN FOLD GTPASE ACTIN POLYMERIZINTEGRIN ACTIVATION CELL ADHESION RIAM RAPL MST1 PDK ENA/VASP PROFILIN MEMBRANE SIGNALING PROTEIN
Ref.: THE STRUCTURE OF RAP1 IN COMPLEX WITH RIAM REVEALS SPECIFICITY DETERMINANTS AND RECRUITMENT MECHANISM. J MOL CELL BIOL V. 6 128 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG A:202;
C:202;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
GTP A:201;
C:201;
Valid;
Valid;
none;
none;
submit data
523.18 C10 H16 N5 O14 P3 c1nc2...
EDO B:501;
D:501;
Invalid;
Invalid;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4KVG 1.65 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF RIAM RA-PH DOMAINS IN COMPLEX WITH GTP HOMO SAPIENS RAS-RELATED PROTEIN UBIQUITIN FOLD GTPASE ACTIN POLYMERIZINTEGRIN ACTIVATION CELL ADHESION RIAM RAPL MST1 PDK ENA/VASP PROFILIN MEMBRANE SIGNALING PROTEIN
Ref.: THE STRUCTURE OF RAP1 IN COMPLEX WITH RIAM REVEALS SPECIFICITY DETERMINANTS AND RECRUITMENT MECHANISM. J MOL CELL BIOL V. 6 128 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 4KVG - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 4KVG - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (11)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 55 families.
1 1GUA Kd = 40 nM GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 3KUC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 1C1Y - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
4 2CJW Kd = 2.5 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 4KVG - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
6 2A9K - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
7 1WQ1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
8 3KUD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
9 5XCO - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
10 1NVU - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
11 4URZ Kd = 3 mM VJP C11 H14 N2 O3 S c1cc(ccc1N....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GTP; Similar ligands found: 147
No: Ligand ECFP6 Tc MDL keys Tc
1 GTP 1 1
2 GP3 0.921053 0.973684
3 GDP 0.909091 1
4 GSP 0.853659 0.948718
5 GNH 0.82716 0.986667
6 G1R 0.819277 0.986667
7 GAV 0.811765 0.961039
8 GNP 0.809524 0.973684
9 GCP 0.797619 0.973684
10 5GP 0.797468 0.986486
11 G 0.797468 0.986486
12 GMV 0.764706 0.973684
13 G2R 0.764045 0.961039
14 G5P 0.755319 0.973684
15 GTG 0.752688 0.936709
16 G2P 0.747126 0.961039
17 G3A 0.744681 0.973684
18 GDD 0.741935 0.961039
19 GKE 0.741935 0.961039
20 GDC 0.741935 0.961039
21 0O2 0.736264 0.986486
22 GP2 0.729412 0.961039
23 6CK 0.726316 0.936709
24 Y9Z 0.723404 0.902439
25 GPG 0.717391 0.961039
26 GFB 0.715789 0.961039
27 GDR 0.715789 0.961039
28 GDP MG 0.712644 0.923077
29 GDP BEF 0.704545 0.9
30 GPD 0.704082 0.925
31 JB2 0.693878 0.961039
32 GKD 0.693878 0.961039
33 GCP G 0.692308 0.935065
34 GDX 0.686869 0.973684
35 ALF 5GP 0.685393 0.888889
36 GTP MG 0.681319 0.923077
37 BEF GDP 0.681319 0.888889
38 GH3 0.681319 0.973333
39 YGP 0.677083 0.901235
40 G3D 0.67033 0.986486
41 GDP AF3 0.659574 0.888889
42 GDP ALF 0.659574 0.888889
43 DGT 0.659341 0.923077
44 GMP 0.658228 0.88
45 G4P 0.655914 0.986486
46 JB3 0.653846 0.948718
47 NGD 0.647619 0.961039
48 CAG 0.642202 0.880952
49 2MD 0.62963 0.891566
50 G G 0.622449 0.935065
51 MGP 0.619565 0.961039
52 U2G 0.616822 0.936709
53 6G0 0.612903 0.961039
54 MGD 0.612613 0.891566
55 TPG 0.608696 0.840909
56 CG2 0.605505 0.936709
57 GDP 7MG 0.601942 0.911392
58 FEG 0.601852 0.879518
59 ZGP 0.59633 0.869048
60 MD1 0.591304 0.891566
61 PGD 0.591304 0.925
62 3GP 0.590909 0.946667
63 GPX 0.581633 0.946667
64 DGI 0.580645 0.923077
65 IDP 0.576087 0.972973
66 DBG 0.567797 0.948718
67 FE9 0.555556 0.776596
68 2GP 0.555556 0.96
69 G4M 0.547619 0.880952
70 BGO 0.544643 0.924051
71 I2C FE2 CMO CMO 0.538462 0.808989
72 ATP 0.537634 0.92
73 G1G 0.533898 0.925
74 AQP 0.531915 0.92
75 5FA 0.531915 0.92
76 G A A A 0.525862 0.923077
77 U A G G 0.521368 0.935065
78 01G 0.518868 0.902439
79 ITT 0.510638 0.868421
80 P2G 0.510638 0.883117
81 GGM 0.504274 0.901235
82 G1R G1R 0.504065 0.924051
83 DGP 0.5 0.910256
84 PGD O 0.5 0.850575
85 MGO 0.5 0.864198
86 P1G 0.5 0.871795
87 DG 0.5 0.910256
88 GTA 0.495495 0.936709
89 B4P 0.489362 0.894737
90 AP5 0.489362 0.894737
91 IMP 0.489362 0.959459
92 7DT 0.484536 0.906667
93 G G U 0.482143 0.935065
94 GPC 0.479339 0.879518
95 G C 0.478992 0.9
96 BA3 0.478723 0.894737
97 ADP 0.473684 0.92
98 G2Q 0.471698 0.961039
99 G7M 0.46875 0.948052
100 25L 0.458716 0.907895
101 A2D 0.457447 0.894737
102 RGT 0.45045 0.909091
103 AGS 0.45 0.873418
104 SAP 0.45 0.873418
105 SGP 0.44898 0.82716
106 U G A 0.448529 0.888889
107 A4P 0.445378 0.869048
108 G G G RPC 0.442623 0.875
109 ACQ 0.441176 0.896104
110 ANP 0.441176 0.896104
111 8GT 0.441176 0.875
112 APC G U 0.44 0.886076
113 G U34 0.438017 0.888889
114 6AD 0.436893 0.841463
115 G G G C 0.433071 0.9125
116 UP5 0.432203 0.873418
117 35G 0.431373 0.933333
118 C2E 0.431373 0.921053
119 PCG 0.431373 0.933333
120 A G C C 0.429688 0.911392
121 5GP 5GP 0.427184 0.883117
122 TAT 0.427184 0.884615
123 APR 0.425743 0.894737
124 AR6 0.425743 0.894737
125 AN2 0.424242 0.907895
126 7DD 0.424242 0.906667
127 DG DG 0.423423 0.865854
128 AD9 0.421569 0.896104
129 M33 0.42 0.883117
130 7D4 0.42 0.835443
131 UCG 0.419847 0.911392
132 H6Y 0.419048 0.946667
133 G C C C 0.416667 0.924051
134 ACP 0.415842 0.896104
135 T5A 0.414634 0.802326
136 MGQ 0.412844 0.935897
137 ADQ 0.412844 0.871795
138 A1R 0.412844 0.839506
139 MGT 0.411215 0.823529
140 A G U 0.410072 0.888889
141 93A 0.41 0.833333
142 A22 0.407407 0.907895
143 CA0 0.405941 0.896104
144 ATF 0.40566 0.884615
145 AGO 0.404762 0.888889
146 MGV 0.401786 0.890244
147 CGP 0.4 0.86747
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4KVG; Ligand: GTP; Similar sites found: 346
This union binding pocket(no: 1) in the query (biounit: 4kvg.bio1) has 26 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5DG2 GAL GLC 0.02091 0.40411 None
2 1T8U A3P 0.005832 0.40887 2.30769
3 3FWY ADP 0.00001306 0.53529 2.38095
4 1WY7 SAH 0.003485 0.4119 2.89855
5 3UIE ANP 0.00008103 0.51093 3
6 2X7I CIT 0.006695 0.42889 3.07692
7 3BP1 GUN 0.0306 0.41457 3.07692
8 4BQS ADP 0.0001214 0.51499 3.40909
9 4BQS K2Q 0.004894 0.41205 3.40909
10 2JLR ANP 0.0002942 0.47928 3.57143
11 5HR5 ADP 0.000256 0.4164 3.57143
12 2VVG ADP 0.0000004971 0.41447 3.57143
13 2GWH A3P 0.006471 0.41371 3.57143
14 2IYL GDP 0.000005484 0.58145 3.84615
15 1XP8 AGS 0.00052 0.48975 3.84615
16 1VBO MAN 0.01297 0.41958 4.02685
17 1VBO MAN MAN MAN 0.02397 0.4091 4.02685
18 4LPS GDP 0.0000001231 0.65304 4.16667
19 4BAS GNP 0.000000006238 0.61042 4.16667
20 3NHB ADP 0.00002313 0.57318 4.16667
21 3BFV ADP 0.00004177 0.53789 4.16667
22 1G3Q ADP 0.00006233 0.52261 4.16667
23 1ION ADP 0.0001095 0.50478 4.16667
24 1D2N ANP 0.003027 0.42121 4.16667
25 1BG2 ADP 0.000001829 0.40169 4.16667
26 3QXC ATP 0.003595 0.40001 4.16667
27 5HCN GCP 0.0000000004758 0.76942 4.21456
28 2HXW FLC 0.02405 0.4093 4.21941
29 1P9B GDP 0.0003504 0.47087 4.23077
30 1P9B HDA 0.01162 0.42787 4.23077
31 1JJV ATP 0.0000302 0.56507 4.36893
32 1VHT BA3 0.0006261 0.46908 4.58716
33 3WV1 WHH 0.01004 0.40613 4.67836
34 1SVI GDP 0.0000000003403 0.80299 4.7619
35 2WHX ADP 0.00003058 0.56638 4.7619
36 1H65 GDP 0.000007615 0.52796 4.7619
37 3BOS CDP 0.0001483 0.5107 4.7619
38 1FNN ADP 0.0001492 0.48256 4.7619
39 2GK6 ADP 0.001498 0.47224 4.7619
40 1NJF AGS 0.00009238 0.45161 4.7619
41 1NJF ADP 0.00008495 0.44003 4.7619
42 2WZF BGC 0.007217 0.43914 4.7619
43 1L2T ATP 0.001254 0.4269 4.7619
44 3COB ADP 0.000001265 0.41764 4.7619
45 2Z5F A3P 0.005862 0.40877 4.7619
46 2NCD ADP 0.000008901 0.59428 5
47 1XKV ATP 0.0002709 0.48623 5
48 2KIN ADP 0.000002189 0.40036 5
49 4MKG AP5 0.001811 0.4348 5.06912
50 4TTQ ATP 0.0001361 0.51254 5.11628
51 3A1S GDP 0.00000002539 0.68612 5.35714
52 2WIC GNP 0.00000004472 0.67425 5.35714
53 5KSP GDP 0.0000000524 0.67094 5.35714
54 5KSZ GCP 0.00000008274 0.65188 5.35714
55 1G6H ADP 0.000003584 0.62994 5.35714
56 4WZ6 ATP 0.0000148 0.58376 5.35714
57 2QZ4 ADP 0.0000492 0.52114 5.35714
58 2FAH GDP 0.0002816 0.48016 5.35714
59 4R98 GNH 0.000001478 0.47455 5.35714
60 1YTM ATP 0.0002882 0.4654 5.35714
61 2OFW ADX 0.0013 0.43975 5.35714
62 4A4Z ANP 0.005239 0.43416 5.35714
63 4MKF AP5 0.002402 0.43068 5.35714
64 3RC3 ANP 0.01024 0.42408 5.35714
65 3BFX A3P 0.004325 0.41797 5.35714
66 4FRZ ADP 0.000006887 0.41235 5.35714
67 5TSH ANP 0.00005215 0.41108 5.35714
68 5GJC ATP 0.00007269 0.40684 5.35714
69 1APZ ASP 0.02889 0.4051 5.35714
70 1BO4 COA 0.02267 0.40254 5.35714
71 1W5T ANP 0.0005404 0.45359 5.38462
72 1W5T ADP 0.0009012 0.45236 5.38462
73 1LVG ADP 0.000002901 0.42966 5.55556
74 4MZQ 1VU 0.004929 0.41546 5.55556
75 3DKP ADP 0.0003268 0.49375 5.71429
76 1T5C ADP 0.000005052 0.61729 5.76923
77 1YQT ADP 0.00002408 0.57297 5.76923
78 3ZFD ANP 0.00000005024 0.52821 5.76923
79 4GOX A3P 0.001166 0.43168 5.76923
80 3R7F CP 0.01729 0.4189 5.76923
81 2PL3 ADP 0.0004013 0.49545 5.9322
82 1SKQ GDP 0.00000001015 0.7283 5.95238
83 3DC4 ADP 0.000000764 0.64341 5.95238
84 2ZFI ADP 0.000008268 0.57264 5.95238
85 2B8W ALF 5GP 0.000004589 0.52625 5.95238
86 1F5N GNP 0.000005397 0.50946 5.95238
87 2C04 GCP 0.00009099 0.49727 5.95238
88 3ZS9 ADP ALF 0.00003539 0.47804 5.95238
89 2WOJ ADP ALF 0.00004899 0.47259 5.95238
90 4YS0 ADP 0.0008987 0.45242 5.95238
91 2IXE ATP 0.0005659 0.44865 5.95238
92 4IOK XPO 0.0007489 0.43603 5.95238
93 4IOK ADP 0.0009293 0.41811 5.95238
94 5X40 ACP 0.0009996 0.41749 5.95238
95 1O8B ABF 0.01876 0.41067 5.95238
96 3PQC GDP 0.00000002067 0.68027 6.15385
97 5LB3 ADP 0.000169 0.51447 6.15385
98 4R2I ANP 0.001982 0.46591 6.19048
99 4D81 ADP 0.0001476 0.41887 6.53846
100 1JWY GDP 0.000001712 0.58228 6.54762
101 1JWY ADP 0.00001622 0.55081 6.54762
102 5BQ5 ADP BEF 0.00005367 0.51936 6.54762
103 2CHG ANP 0.0002371 0.47851 6.54762
104 5MZN ADP 0.001594 0.47083 6.54762
105 1IN4 ADP 0.000358 0.46578 6.54762
106 4Q1A 2XZ 0.00688 0.45728 6.54762
107 4Q1A UDP 0.00688 0.45728 6.54762
108 4KBF AMP 0.002462 0.45552 6.54762
109 4U60 SIA 0.01264 0.41782 6.54762
110 4P32 ADP 0.003168 0.41692 6.54762
111 4U60 SIA GAL NGA 0.01246 0.41649 6.54762
112 2Y65 ADP 0.000007149 0.40125 6.54762
113 4U60 SIA GAL BGC NGA GAL 0.02908 0.40091 6.54762
114 1GXU 2HP 0.0002855 0.49553 6.59341
115 4KFU ACP 0.00001729 0.57883 6.60377
116 4PU6 ASP 0.02292 0.4104 6.87023
117 1MKY GDP 0.0000000001744 0.80364 6.92308
118 2DPY ADP 0.0001503 0.52416 6.92308
119 4IEE AGS 0.0003987 0.49559 6.92308
120 3QDK QDK 0.04673 0.40077 6.92308
121 1OS1 ATP 0.002058 0.40022 6.92308
122 2XTN GTP 0.0000005676 0.56937 7.14286
123 5KUT GDP 0.000000001297 0.5638 7.14286
124 4QM7 GTP 0.00009816 0.51955 7.14286
125 2J5V PCA 0.02879 0.42515 7.14286
126 3FVQ ATP 0.0004044 0.45904 7.30769
127 1NY5 ADP 0.000883 0.45276 7.30769
128 1F9V ADP 0.000007464 0.41245 7.30769
129 2FH5 GTP 0.000000000001647 0.82186 7.56757
130 1B0U ATP 0.001035 0.4541 7.63359
131 2C77 GNP 0.0000000001413 0.73825 7.69231
132 2C78 GNP 0.0000000001009 0.7347 7.69231
133 1JJ7 ADP 0.000003413 0.63124 7.69231
134 5I0H ADP BEF 0.0000005795 0.52719 7.69231
135 3DZD ADP 0.0005267 0.46762 7.69231
136 3KTA AP5 0.0006974 0.462 7.69231
137 3WXM GTP 0.0000000002357 0.69269 7.7381
138 1TAD GDP 0.000000005739 0.60637 7.7381
139 1TAD ALF 0.000000005739 0.60637 7.7381
140 4NON GDP 0.0000001199 0.563 7.7381
141 1IHU AF3 0.0001019 0.48021 7.7381
142 1IHU ADP 0.0001293 0.47139 7.7381
143 3VM7 GLC 0.008393 0.44442 7.7381
144 4PJ3 ANP 0.002719 0.43475 7.7381
145 2PEZ DAT 0.001419 0.43057 7.7381
146 2PEZ GGZ 0.001419 0.43057 7.7381
147 3BER AMP 0.009897 0.42047 7.7381
148 5H56 TYD 0.002738 0.41605 7.7381
149 5H56 ADP 0.002738 0.41605 7.7381
150 4FCW ADP 0.0002985 0.40096 7.7381
151 1UKZ ADP 0.007389 0.40221 7.88177
152 1PTR PRB 0.02476 0.40897 8
153 2HCJ GDP 0.0000000001929 0.56209 8.0597
154 1XMV ADP 0.000302 0.48956 8.07692
155 4RLQ 3SK 0.0346 0.40097 8.07692
156 3H4S ADP 0.000002259 0.41257 8.14815
157 1GOJ ADP 0.0000004429 0.67707 8.33333
158 2ODE ALF GDP 0.000000001964 0.66434 8.33333
159 1SVK ALF GDP 0.000000002956 0.65974 8.33333
160 1BH2 GSP 0.000000002241 0.62023 8.33333
161 1Y3A GDP 0.0000003619 0.5775 8.33333
162 3E70 GDP 0.000006484 0.57002 8.33333
163 2OM2 GDP 0.000001711 0.56168 8.33333
164 1GP2 GDP 0.000001291 0.55454 8.33333
165 5M04 GDP 0.000000001809 0.54162 8.33333
166 5L3R GCP 0.000001977 0.54116 8.33333
167 2OG2 MLI 0.00005834 0.54046 8.33333
168 3B9Q MLI 0.000115 0.53143 8.33333
169 1R6B ADP 0.00007851 0.51778 8.33333
170 4LJ9 ACP 0.0007684 0.4754 8.33333
171 2VB6 ADP BEF 0.00004014 0.47155 8.33333
172 4PFO ADP 0.0001755 0.45774 8.33333
173 3QKT ANP 0.001429 0.42458 8.33333
174 2CE7 ADP 0.0001149 0.41381 8.33333
175 1NHX FTB 0.01251 0.40292 8.46154
176 1NHX PEP 0.01269 0.40175 8.46154
177 1NRJ GTP 0.000000001218 0.6978 8.7156
178 1MR3 G3D 0.000000004413 0.55357 8.83978
179 1AZT GSP 0.0000000008967 0.63477 8.84615
180 3H86 AP5 0.0008709 0.44205 8.85417
181 2RCN GDP 0.00000000005117 0.82995 8.92857
182 1V8K ANP 0.0000005594 0.63042 8.92857
183 1SQ5 ADP 0.0000762 0.5184 8.92857
184 1QHG ATP 0.005963 0.41901 8.92857
185 4UOX PUT 0.006933 0.41598 8.92857
186 4YMU ATP 0.00003812 0.40376 8.92857
187 2XAU ADP 0.0009886 0.45973 9.23077
188 1KK1 GNP 0.000000004632 0.74556 9.52381
189 1OXV ANP 0.00006753 0.53466 9.52381
190 2D2F ADP 0.0004222 0.51231 9.52381
191 2QEN ADP 0.0001464 0.48796 9.52381
192 2GDJ ANP 0.0001313 0.51332 9.61539
193 4GBM A3P 0.002958 0.41487 9.61539
194 3FYH ADP 0.003158 0.41053 9.61539
195 1G8S MET 0.009407 0.43185 10
196 3MD0 GDP 0.000000002524 0.75891 10.119
197 2HF9 GSP 0.00000009261 0.63219 10.119
198 1G6O ADP 0.0001898 0.49351 10.119
199 4R43 GDP 0.000398 0.48952 10.119
200 1Z6T ADP 0.000339 0.47151 10.119
201 1OYY AGS 0.004961 0.43534 10.119
202 5I34 GDP 0.00005354 0.42553 10.119
203 4MDB RLT 0.0377 0.40125 10.2222
204 1OFH ADP 0.0001002 0.5066 10.3448
205 1UPR 4IP 0.04354 0.41136 10.5691
206 3TK1 GDP 0.0000000005107 0.80846 10.7143
207 4LC1 GDP 0.000000003131 0.74169 10.7143
208 1TQ4 GDP 0.00000002989 0.63769 10.7143
209 1G41 ADP 0.00007278 0.51313 10.7143
210 2BEK ATP 0.0002477 0.46386 10.7143
211 4OI4 ATP 0.001315 0.42951 10.7143
212 1YXM ADE 0.03244 0.41274 10.7692
213 3VX3 ADP 0.0001594 0.48129 10.8871
214 4CVN ADP 0.00001479 0.57651 10.9948
215 1UPT GTP 0.00000000005746 0.74506 11.3095
216 3IIJ ADP 0.00001256 0.56366 11.3095
217 2C9O ADP 0.00006632 0.493 11.3095
218 1R4A GNP 0.0000000000795 0.72038 11.5152
219 4ZG4 VO4 ADP 0.000001895 0.52271 11.5385
220 1FQK ALF 0.000000867 0.6518 11.5646
221 1FQK GDP 0.000000181 0.59 11.5646
222 1FQJ ALF 0.0000009665 0.64394 11.9048
223 1FQJ GDP 0.00000008361 0.60394 11.9048
224 1FP6 ADP 0.00004312 0.51771 11.9048
225 3B7G ANP 0.0006732 0.47276 11.9048
226 1QF5 RPL 0.006668 0.44701 11.9048
227 2AWN ADP 0.0000006493 0.67979 11.9231
228 4AG5 ADP 0.00001281 0.58646 11.9231
229 3TBK ANP 0.0006586 0.4908 11.9231
230 3RLF ANP 0.0004861 0.44748 11.9231
231 1X6V ADP 0.00131 0.40669 11.9231
232 1F2U ATP 0.002475 0.40609 12.1622
233 1WF3 GNP 0.0000000004498 0.68454 12.3077
234 4HSE ADP 0.00004268 0.53054 12.3077
235 1GOT GDP 0.0000006062 0.57454 12.3288
236 4H1V GNP 0.000003426 0.56148 12.5
237 5N69 ADP 0.00002047 0.53262 12.5
238 2ZR9 DTP 0.0002245 0.5018 12.5
239 1U0J ADP 0.0007678 0.48117 12.5
240 1KO8 6PG 0.000707 0.40752 12.5714
241 5L3V GDP 0.000004749 0.56899 13.0769
242 5CK5 GDP 0.0000000002464 0.56289 13.0952
243 2BIF SIN 0.00179 0.43824 13.0952
244 2BIF ANP 0.0009987 0.43824 13.0952
245 1K6M AGS 0.001474 0.42745 13.0952
246 1W7J ADP BEF 0.000008632 0.54339 13.245
247 4IHQ ADP 0.0006638 0.48438 13.4615
248 5L3S GNP 0.000008357 0.50452 13.6905
249 5L3W GDP 0.00001378 0.45364 13.6905
250 3P4X ADP 0.00008219 0.40309 13.6905
251 2IS6 ADP 0.00009263 0.5208 13.8462
252 2Q2Y ADP 0.0006413 0.4539 13.8462
253 2Q2Y MKR 0.0007119 0.45079 13.8462
254 1JI0 ATP 0.000049 0.54947 14.1667
255 1G7C 5GP 0.0000004568 0.63477 14.2308
256 3ZQ6 ADP ALF 0.00002955 0.48089 14.2308
257 2D7D ADP 0.001093 0.46783 14.2857
258 1ZUI SKM 0.0002358 0.40298 14.2857
259 3ZIA ATP 0.00005636 0.52472 14.881
260 3ZIA ADP 0.0001289 0.49579 14.881
261 4WOP CTP 0.00003246 0.46229 15.1111
262 1KK8 BEF ADP 0.00001495 0.53263 15.4762
263 1B7T ADP 0.00003658 0.52721 15.4762
264 4XTR ATP 0.000103 0.45684 15.6522
265 4XVU ATP 0.0001091 0.45595 15.6522
266 4XTR ADP 0.00009775 0.44043 15.6522
267 1G7S GDP 0.000000003278 0.72899 16.0714
268 2XT3 ADP 0.000002115 0.63342 16.0714
269 2GJ8 ALF GDP 0.0000000002983 0.67397 16.6667
270 3CX8 GSP 0.0000000008015 0.63661 16.6667
271 3AB3 GDP 0.00000004394 0.57362 16.6667
272 1M7G AV2 0.00001496 0.56781 16.6667
273 4QOS ADP 0.0006676 0.46777 16.6667
274 1M7G ADP 0.001314 0.40558 16.6667
275 1D2E GDP 0.00000001697 0.67461 16.9231
276 4B47 GDP 0.0000000001232 0.82533 17.2619
277 1DAR GDP 0.00000003399 0.69052 17.2619
278 3DEF GDP 0.000001582 0.58385 17.2619
279 4V0K GDP 0.0000007879 0.55745 17.2619
280 3KJI ADP 0.00007441 0.43359 17.2619
281 2ZPA ADP 0.0002811 0.42136 17.2619
282 2VF7 ADP 0.0005886 0.47557 17.6923
283 4NCN GTP 0.000000000007573 0.77197 17.8571
284 1CS4 GSP 0.000000001181 0.64138 17.8571
285 2V7Q ADP 0.00006397 0.52874 17.8571
286 2V7Q ATP 0.00008952 0.50889 17.8571
287 4IDN GNP 0.00003113 0.50204 17.8571
288 2CK3 ANP 0.0003979 0.46375 17.8571
289 2CK3 ADP 0.0006267 0.4429 17.8571
290 1W0J ADP 0.0001197 0.42495 17.8571
291 1W0J ADP BEF 0.0004243 0.41622 17.8571
292 3W5J GDP 0.00000216 0.62925 18.1373
293 1PUJ GNP 0.000000002281 0.71477 18.4524
294 2BVN GNP 0.00000000007749 0.78246 19.0476
295 1D8T GDP 0.0000000005735 0.7781 19.0476
296 2W58 ADP 0.0000001681 0.71178 19.0476
297 1YRB GDP 0.000000000165 0.76733 19.6429
298 5XVQ 8GC 0.03695 0.40171 19.6429
299 4DCT GDP 0.0000000003467 0.77605 20.2381
300 2XTZ GSP 0.0000000001849 0.69691 20.2381
301 5KDO GDP 0.00000122 0.56803 20.2703
302 2WJG GDP 0.00000002063 0.70124 20.8333
303 3T12 GDP ALF 0.000000009559 0.65092 20.8333
304 3T1O GDP 0.0000004648 0.50109 20.8333
305 1QAN SAH 0.001015 0.43419 20.8333
306 4HI0 GDP 0.0000004027 0.58885 21.4286
307 1CR1 TTP 0.0008762 0.40957 21.4286
308 3QF7 ANP 0.001187 0.43235 22
309 3EC1 GDP 0.000000007285 0.54507 22.0238
310 2WJH GDP 0.0000000164 0.54323 23.494
311 2WJH FLC 0.000001504 0.48255 23.494
312 3A4M ADP 0.000009843 0.5857 24.4048
313 1M2O GNP 0.000000001949 0.65599 26.1905
314 2QTV GNP 0.000000001523 0.65182 26.3473
315 1FZQ GDP 0.000000000771 0.77175 26.7857
316 4M9Q GNP 0.00000000009899 0.73505 26.7857
317 3B5J 12D 0.00005627 0.54634 26.7857
318 1F6B GDP 0.00000003759 0.6779 27.9762
319 2A5F GTP 0.0000000008116 0.67924 29.1667
320 1KSH GDP 0.00000000007046 0.6702 29.7619
321 1J2J GTP 0.00000000005862 0.73503 30.1205
322 1O3Y GTP 0.0000000002758 0.70708 30.1205
323 1YZG GDP 0.000000009499 0.70671 30.3571
324 1S9D GDP 0.00000001536 0.69664 30.4878
325 1RE0 GDP 0.000000001486 0.54188 30.4878
326 1ZJ6 G3D 0.000000007737 0.711 30.9524
327 4P4T GDP 0.000004599 0.54927 31.5476
328 2ZEJ GDP 0.000001398 0.53212 33.3333
329 1ZD9 GDP 0.00000000004566 0.77012 34.5238
330 4WZA ADP 0.00007905 0.51188 34.5238
331 4WZA ACP 0.00007905 0.51188 34.5238
332 5FG3 GDP 0.00000000006548 0.57389 38.0952
333 1QHH ATP 0.01145 0.41329 39.1304
334 2QN6 GDP 0.0000000005258 0.79342 42.2619
335 4RD0 GDP 0.0000000000232 0.69937 42.2619
336 1NF3 GNP 0.0000000000006065 0.7963 47.0238
337 2NGR GDP 0.000000000004031 0.86935 48.2143
338 1GRN GDP 0.00000000001058 0.80992 48.2143
339 4DID GDP 0.0000000005344 0.76699 48.2143
340 2NGR AF3 0.00000001934 0.72641 48.2143
341 1GRN AF3 0.000000163 0.67829 48.2143
342 4ITR GDP 0.00000001061 0.66566 48.2143
343 1A4R GNH 0.00000000005131 0.77901 48.8095
344 1A4R GDP 0.00000000007118 0.76161 48.8095
345 1M7B GTP 0.0000000000009927 0.83137 49.4048
346 1GWN GTP 0.0000000000009182 0.74056 49.4048
347 3GJ4 GDP 0.00000000009313 0.8171 50
348 3GJ7 GDP 0.00000000009607 0.81644 50
349 3GJ8 GDP 0.0000000002945 0.77947 50
350 3GJ5 GDP 0.0000000002994 0.77912 50
351 1MH1 GNP 0.000000000004894 0.76352 50
Pocket No.: 2; Query (leader) PDB : 4KVG; Ligand: GTP; Similar sites found: 15
This union binding pocket(no: 2) in the query (biounit: 4kvg.bio2) has 26 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3QOX SAH 0.004015 0.40035 4.16667
2 3CM2 X23 0.0297 0.4066 4.61538
3 4NZ6 DGL 0.03029 0.40604 4.7619
4 1T3D CYS 0.009959 0.42375 5.35714
5 2BVE PH5 0.02438 0.40652 5.88235
6 2Z48 NGA 0.004202 0.45268 5.95238
7 3VPD CIT 0.03268 0.4139 6.54762
8 4I9B 1KA 0.01078 0.42653 6.92308
9 1UJ5 5RP 0.01339 0.40999 7.7381
10 4Z2S NAG 0.03592 0.40123 10.5634
11 4Z2S NDG 0.03592 0.40123 10.5634
12 5M6N 7H9 0.02052 0.41293 11.8644
13 2ATJ BHO 0.02724 0.40158 13.0952
14 2Q37 3AL 0.0208 0.41385 14.881
15 1M7G ADX 0.0009576 0.40024 16.6667
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