Receptor
PDB id Resolution Class Description Source Keywords
4LIT 2.4 Å EC: 1.14.11.- STRUCTURE OF YCFD A RIBOSOMAL OXYGENASE FROM ESCHERICHIA COL COMPLEX WITH COBALT AND 2-OXOGLUTARATE. ESCHERICHIA COLI JMJC DOMAIN DIOXYGENASE HYDROXYLATION OXIDOREDUCTASE
Ref.: RIBOSOMAL OXYGENASES ARE STRUCTURALLY CONSERVED FRO PROKARYOTES TO HUMANS. NATURE V. 509 422 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
AKG A:502;
Valid;
none;
submit data
146.098 C5 H6 O5 C(CC(...
CO A:501;
Part of Protein;
none;
submit data
58.933 Co [Co+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4LIT 2.4 Å EC: 1.14.11.- STRUCTURE OF YCFD A RIBOSOMAL OXYGENASE FROM ESCHERICHIA COL COMPLEX WITH COBALT AND 2-OXOGLUTARATE. ESCHERICHIA COLI JMJC DOMAIN DIOXYGENASE HYDROXYLATION OXIDOREDUCTASE
Ref.: RIBOSOMAL OXYGENASES ARE STRUCTURALLY CONSERVED FRO PROKARYOTES TO HUMANS. NATURE V. 509 422 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 31 families.
1 4LIT - AKG C5 H6 O5 C(CC(=O)O)....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 19 families.
1 4LIT - AKG C5 H6 O5 C(CC(=O)O)....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 17 families.
1 4LIT - AKG C5 H6 O5 C(CC(=O)O)....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: AKG; Similar ligands found: 7
No: Ligand ECFP6 Tc MDL keys Tc
1 AKG 1 1
2 SIN 0.526316 0.833333
3 OOG 0.5 0.947368
4 69O 0.458333 0.714286
5 2IT 0.423077 0.615385
6 SHF 0.416667 0.666667
7 3PY 0.409091 0.652174
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4LIT; Ligand: AKG; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4lit.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 4LIT; Ligand: AKG; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4lit.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
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