Receptor
PDB id Resolution Class Description Source Keywords
4LPS 2 Å EC: 7.-.-.- CRYSTAL STRUCTURE OF HYPB FROM HELICOBACTER PYLORI IN COMPLE NICKEL HELICOBACTER PYLORI METAL BINDING PROTEIN HYDROGENASE NICKEL INCORPORATION GTPA
Ref.: RELATIONSHIP BETWEEN NI(II) AND ZN(II) COORDINATION NUCLEOTIDE BINDING BY THE HELICOBACTER PYLORI [NIFE]-HYDROGENASE AND UREASE MATURATION FACTOR HYP J.BIOL.CHEM. V. 289 3828 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PO4 A:307;
B:306;
A:303;
B:307;
B:303;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
submit data
94.971 O4 P [O-]P...
GOL B:305;
A:310;
B:309;
A:305;
B:304;
A:306;
B:310;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
GDP A:302;
B:302;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
MLI A:308;
A:309;
B:308;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
102.046 C3 H2 O4 C(C(=...
MG B:301;
A:301;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
NI A:304;
Part of Protein;
none;
submit data
58.693 Ni [Ni+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4LPS 2 Å EC: 7.-.-.- CRYSTAL STRUCTURE OF HYPB FROM HELICOBACTER PYLORI IN COMPLE NICKEL HELICOBACTER PYLORI METAL BINDING PROTEIN HYDROGENASE NICKEL INCORPORATION GTPA
Ref.: RELATIONSHIP BETWEEN NI(II) AND ZN(II) COORDINATION NUCLEOTIDE BINDING BY THE HELICOBACTER PYLORI [NIFE]-HYDROGENASE AND UREASE MATURATION FACTOR HYP J.BIOL.CHEM. V. 289 3828 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 250 families.
1 4LPS - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 217 families.
1 4LPS - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 181 families.
1 4LPS - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4LPS; Ligand: GDP; Similar sites found: 554
This union binding pocket(no: 1) in the query (biounit: 4lps.bio2) has 17 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1VG1 GDP 0.00000001812 0.66247 None
2 1VG8 GNP 0.0000001872 0.64677 None
3 5UQW GDP 0.0000001674 0.64399 None
4 4YDS ATP 0.00003282 0.53578 None
5 5IRR GSP 0.0000002617 0.52804 None
6 1DAK DPU 0.00146 0.47659 None
7 4WOP CTP 0.0002687 0.42646 None
8 3EVF GTA 0.02819 0.41 1.23967
9 2ORV 4TA 0.01053 0.41506 1.28205
10 1M7G ADX 0.00007398 0.52807 1.4218
11 1M7G AV2 0.000006817 0.52111 1.4218
12 1M7G ADP 0.0000957 0.51918 1.4218
13 2WJG GDP 0.00000000899 0.6876 1.59574
14 3CNL GNP 0.000000001484 0.67711 1.65289
15 1UJ2 ADP 0.00003814 0.5349 1.65289
16 1UJ2 C5P 0.00004935 0.52948 1.65289
17 3FYH ADP 0.0001532 0.50183 1.65289
18 2GDJ ANP 0.000071 0.48803 1.65289
19 4PX9 ADP 0.000474 0.47189 1.65289
20 1XTQ GDP 0.0000001957 0.63802 1.69492
21 1EK0 GNP 0.0000008007 0.61382 1.76471
22 3ZQ6 ADP ALF 0.00006841 0.52261 2.06612
23 3EWA ANP 0.00004072 0.49854 2.06612
24 1G41 ADP 0.0001385 0.48752 2.06612
25 4KBF AMP 0.001128 0.42975 2.06612
26 1QHG ATP 0.005739 0.41508 2.06612
27 1YZN GNP 0.0000001525 0.49273 2.16216
28 2QQ0 ANP 0.0007578 0.47976 2.17391
29 2QQ0 THM 0.00066 0.47976 2.17391
30 2QQ0 TMP 0.0007951 0.47873 2.17391
31 2YOH WMJ 0.00002035 0.40442 2.38095
32 4J0Q GDP 0.000000004931 0.71209 2.47934
33 3U6B GDP 0.000000008297 0.7012 2.47934
34 5JBQ GDP 0.00000001485 0.67738 2.47934
35 3U6K GDP 0.00000002074 0.67056 2.47934
36 2HCJ GDP 0.000000005722 0.6519 2.47934
37 4G5G GDP 0.00000001782 0.64735 2.47934
38 1D8T GDP 0.00000002078 0.64441 2.47934
39 2BVN GNP 0.0000000324 0.61273 2.47934
40 3ZFD ANP 0.0000197 0.52659 2.47934
41 3EZ2 ADP 0.00006726 0.51277 2.47934
42 5HR5 ADP 0.0002005 0.48528 2.47934
43 5HR5 FLC 0.002842 0.45136 2.47934
44 5K5Z ANP 0.00008947 0.42505 2.47934
45 1AQU A3P 0.007113 0.4128 2.47934
46 3ZS9 ADP ALF 0.0003597 0.40361 2.47934
47 5GVR LMR 0.0001395 0.50228 2.5641
48 1XX6 ADP 0.0009752 0.43728 2.6178
49 3RWO GDP 0.0000000521 0.67106 2.7027
50 5M04 GDP 0.0000000414 0.66755 2.89256
51 1IHU ADP 0.00006402 0.5179 2.89256
52 1IHU AF3 0.00006396 0.51571 2.89256
53 1W5T ANP 0.00009679 0.5049 2.89256
54 4R43 GDP 0.0001226 0.49345 2.89256
55 1W5T ADP 0.0003114 0.47635 2.89256
56 5M7P ADP 0.0005164 0.46836 2.89256
57 2B8W ALF 5GP 0.0008937 0.46505 2.89256
58 1P9B GDP 0.0005722 0.464 2.89256
59 5XDR ADP 0.000564 0.45675 2.89256
60 4IOK ADP 0.003228 0.44302 2.89256
61 4IOK XPO 0.002704 0.44195 2.89256
62 5EP2 AZU 0.003682 0.43017 2.89256
63 2X7I CIT 0.004964 0.40848 2.89256
64 5MEX SZZ 0.03815 0.40043 2.89256
65 1R2Q GNP 0.000000006864 0.73355 2.94118
66 3MJH GTP 0.00000005489 0.51361 2.97619
67 3B7G ANP 0.0004488 0.4613 3.04348
68 1OIX GDP 0.00000006352 0.66691 3.14136
69 1OIV GDP 0.00000006734 0.66568 3.14136
70 4DSU GDP 0.0000001436 0.65235 3.1746
71 4AG5 ADP 0.00002012 0.5528 3.30579
72 1V8K ANP 0.000009472 0.52703 3.30579
73 2ZFI ADP 0.00002473 0.5261 3.30579
74 1RRC ADP 0.0000007297 0.51585 3.30579
75 1IWE IMP 0.001263 0.51419 3.30579
76 1OS1 PYR 0.0002602 0.4996 3.30579
77 1OS1 ATP 0.0002408 0.4996 3.30579
78 2FAH GDP 0.00009302 0.49825 3.30579
79 2JL1 NAP 0.0131 0.40736 3.30579
80 3E5H GNP 0.000001055 0.60805 3.37079
81 1RYH GNP 0.00000003108 0.6558 3.44828
82 2HV8 GTP 0.00000007335 0.66389 3.48837
83 3IUY AMP 0.006446 0.40368 3.50877
84 3RAB GNP 0.0000001733 0.64588 3.5503
85 3REF GDP 0.00000004512 0.55035 3.60825
86 3WYA GDP 0.000000003318 0.67991 3.71901
87 3CPJ GDP 0.00000009897 0.63628 3.71901
88 3WY9 GDP 0.00000003004 0.62386 3.71901
89 5HCN GCP 0.0000001345 0.62262 3.71901
90 1DAR GDP 0.0000001104 0.61408 3.71901
91 3A1S GDP 0.0000002425 0.61089 3.71901
92 2BCG GDP 0.00000007152 0.56951 3.71901
93 2IYL GDP 0.000007815 0.53189 3.71901
94 4P32 ADP 0.00005416 0.51914 3.71901
95 2QEN ADP 0.00005073 0.51317 3.71901
96 1BG2 ADP 0.0000003222 0.50856 3.71901
97 1XKV ATP 0.00006419 0.50293 3.71901
98 1Z6T ADP 0.00006685 0.46533 3.71901
99 2Z5F A3P 0.00205 0.44221 3.71901
100 2BEK ATP 0.0001024 0.43335 3.71901
101 2OBM ADP 0.0001565 0.43316 3.71901
102 1Q20 PLO 0.01361 0.4188 3.71901
103 2J5V PCA 0.0165 0.41343 3.71901
104 1FL2 FAD 0.0277 0.41039 3.71901
105 1ZJ6 G3D 0.000000005295 0.68694 3.74332
106 2KIN ADP 0.0000007025 0.49783 3.78151
107 1YZG GDP 0.00000000542 0.68647 3.91061
108 4M9Q GNP 0.0000001391 0.5341 3.96476
109 3NKV GNP 0.00000009506 0.65846 4
110 2F9L GDP 0.00000003558 0.6734 4.0201
111 4BAS GNP 0.0000001137 0.64642 4.0201
112 3PQC GDP 0.0000001746 0.60104 4.10256
113 3SFV GDP 0.0000001122 0.64368 4.13223
114 5GOE GDP 0.00000005097 0.62311 4.13223
115 4PC3 GDP 0.00000003682 0.61417 4.13223
116 3TK1 GDP 0.00000007059 0.59222 4.13223
117 3DEF GDP 0.000004531 0.55918 4.13223
118 2XT3 ADP 0.0000006843 0.51741 4.13223
119 2WKQ GTP 0.0000002366 0.51667 4.13223
120 4NON GDP 0.00000002988 0.50669 4.13223
121 3A4M ADP 0.000008133 0.50606 4.13223
122 5LB3 ADP 0.00009409 0.50574 4.13223
123 4GOX A3P 0.000125 0.50402 4.13223
124 2Y65 ADP 0.000001857 0.50237 4.13223
125 1G6H ADP 0.0000007055 0.49553 4.13223
126 4IHQ ADP 0.0001288 0.46909 4.13223
127 1YTM ATP 0.00006362 0.45233 4.13223
128 2FNA ADP 0.00003843 0.44819 4.13223
129 1OYY AGS 0.001259 0.43417 4.13223
130 1T8U UAP SGN IDS SGN 0.01432 0.4241 4.13223
131 1T8U A3P 0.004996 0.42389 4.13223
132 1NST A3P 0.0114 0.40318 4.13223
133 4KVG GTP 0.0000001231 0.65304 4.16667
134 3FB4 AP5 0.00007388 0.53992 4.16667
135 1ZUI SKM 0.00008039 0.53252 4.16667
136 2D7C GTP 0.00000003252 0.68093 4.19162
137 1GUA GNP 0.0000001471 0.49286 4.19162
138 3X1Z GNP 0.0000001574 0.4834 4.19162
139 1Z06 GNP 0.0000003801 0.6269 4.2328
140 5BQ5 ADP BEF 0.0001473 0.47197 4.2328
141 1QXA GLY GLY GLY 0.01325 0.40561 4.25532
142 2CUL FAD 0.03315 0.40256 4.31034
143 3AQ4 GDP 0.000000007361 0.68039 4.34783
144 2F3R G5P 0.004958 0.4394 4.34783
145 2CHG ANP 0.00006283 0.50883 4.42478
146 1S8F GDP 0.00000003275 0.68603 4.51977
147 2RCN GDP 0.00000000293 0.68239 4.54545
148 2C77 GNP 0.00000003657 0.66669 4.54545
149 4LX0 BEF GDP 0.00000007298 0.66659 4.54545
150 4R98 GNH 0.00000009573 0.63936 4.54545
151 2XTZ GSP 0.0000003073 0.63388 4.54545
152 4WZ6 ATP 0.000003813 0.59022 4.54545
153 2C78 GNP 0.00000003919 0.55013 4.54545
154 3B9Q MLI 0.00003111 0.54849 4.54545
155 1CR1 TTP 0.00003573 0.52536 4.54545
156 1NJF AGS 0.00004965 0.52094 4.54545
157 2IXE ATP 0.00006572 0.51515 4.54545
158 1R0X ATP 0.00001223 0.50958 4.54545
159 1NJF ADP 0.00008705 0.5047 4.54545
160 1JJ7 ADP 0.0000004043 0.5026 4.54545
161 5LTJ ADP 0.00008298 0.49486 4.54545
162 2JLR ANP 0.0001401 0.49 4.54545
163 2WHX ADP 0.000008825 0.48972 4.54545
164 1XMV ADP 0.0001102 0.48922 4.54545
165 3BOS CDP 0.00009834 0.48121 4.54545
166 3FKQ ATP 0.0001551 0.45138 4.54545
167 2GWH A3P 0.01126 0.40343 4.54545
168 2OG2 MLI 0.00002278 0.40008 4.54545
169 2A5F GTP 0.00000001338 0.69666 4.57143
170 4YMU ATP 0.00001751 0.54095 4.58333
171 1OFH ADP 0.00009204 0.49571 4.5977
172 3T5G GDP 0.00000006195 0.64199 4.60526
173 1S3G AP5 0.00007317 0.54013 4.60829
174 4MKG AP5 0.00008525 0.53678 4.60829
175 1ZIN AP5 0.0001077 0.53165 4.60829
176 1F2U ATP 0.0005244 0.47975 4.69799
177 2PZE ATP 0.0000007572 0.51025 4.80349
178 2OFW ADX 0.00002923 0.55889 4.80769
179 2J59 GTP 0.00000004034 0.67079 4.81928
180 1O3Y GTP 0.00000007581 0.6577 4.81928
181 1J2J GTP 0.00000004594 0.53959 4.81928
182 1RE0 GDP 0.00000001441 0.637 4.87805
183 1S9D GDP 0.00000001692 0.66384 4.92611
184 5G41 AP5 0.000008716 0.59371 4.93274
185 3N5C GDP 0.00000002513 0.66664 4.93827
186 3PCR GTP 0.0000003441 0.51356 4.93827
187 4P3Y GDP 0.0000000142 0.63586 4.94506
188 1KY3 GDP 0.0000002674 0.61624 4.94506
189 1KK1 GNP 0.000000008648 0.64523 4.95868
190 2EFE GNH 0.0000001268 0.63128 4.95868
191 3VMF GTP 0.0000004928 0.62399 4.95868
192 2VB6 ADP BEF 0.00007842 0.51369 4.95868
193 1K6M AGS 0.0002025 0.49401 4.95868
194 3KJI ADP 0.0001523 0.48832 4.95868
195 1G6O ADP 0.00007419 0.48417 4.95868
196 4V03 ADP 0.0001096 0.47753 4.95868
197 1D2N ANP 0.0005019 0.47111 4.95868
198 4XTR ADP 0.0002543 0.43498 4.95868
199 2GK6 ADP 0.0009655 0.42357 4.95868
200 4XTR ATP 0.0003273 0.40958 4.95868
201 4XVU ATP 0.0003983 0.40795 4.95868
202 1MR3 G3D 0.00000001275 0.66947 4.97238
203 4U5X GNP 0.00000002562 0.67067 5.05618
204 1X1R GDP 0.0000002364 0.64186 5.05618
205 2CBZ ATP 0.0000001631 0.68397 5.06329
206 1HTW ADP 0.0000065 0.54551 5.06329
207 4MKF AP5 0.0000897 0.53695 5.06912
208 2ZTS ADP 0.0000869 0.44819 5.17928
209 2W83 GTP 0.00000005164 0.66567 5.19481
210 4YLG GDP 0.000000009981 0.61671 5.20231
211 1E96 GTP 0.0000003732 0.62981 5.20833
212 3H86 AP5 0.003446 0.44976 5.20833
213 5WDR GNP 0.0000001397 0.65293 5.26316
214 3TKL GTP 0.00000007716 0.66014 5.3719
215 4ZKD GDP 0.0000004379 0.62889 5.3719
216 1G7S GDP 0.000000281 0.60797 5.3719
217 3B5J 12D 0.000006368 0.50842 5.3719
218 3IO3 ADP 0.0001405 0.49493 5.3719
219 3DZD ADP 0.0002833 0.4758 5.3719
220 4QOS ADP 0.0003573 0.45562 5.3719
221 1XP8 AGS 0.0004927 0.44374 5.3719
222 3BER AMP 0.006908 0.41116 5.3719
223 3CV2 OXL 0.02424 0.40252 5.3719
224 2WPB ZZI 0.01678 0.40141 5.3719
225 4IDN GNP 0.0008184 0.40081 5.3719
226 4GOJ GNP 0.000000181 0.63682 5.41667
227 1R4A GNP 0.000000009668 0.70344 5.45455
228 1FZQ GDP 0.00000007291 0.62119 5.52486
229 4BQS ADP 0.000003482 0.56608 5.68182
230 3KTA AP5 0.0001213 0.4929 5.78035
231 1SKQ GDP 0.00000001901 0.63069 5.78512
232 5JCZ GDP 0.0000001388 0.55614 5.78512
233 2VVG ADP 0.000000265 0.5123 5.78512
234 4LYA ATP 0.00006612 0.49938 5.78512
235 1QF5 GDP 0.0007675 0.49799 5.78512
236 2DPY ADP 0.0002549 0.49168 5.78512
237 4D81 ADP 0.00003916 0.48625 5.78512
238 1QF5 RPL 0.01347 0.4601 5.78512
239 5J1J ANP 0.00003353 0.44092 5.78512
240 2C9O ADP 0.00009558 0.44028 5.78512
241 1U0J ADP 0.0009065 0.43256 5.78512
242 1M2O GNP 0.0000004862 0.62427 5.78947
243 5H67 ATP 0.001462 0.4378 5.85106
244 1G16 GDP 0.0000004126 0.61981 5.88235
245 2QG6 NMN 0.0002108 0.50071 6.03015
246 1NN5 ANP 0.00006847 0.52973 6.04651
247 1NN5 2DT 0.02109 0.43283 6.04651
248 1F6B GDP 0.0000002389 0.61119 6.06061
249 4OI4 ATP 0.0004304 0.47836 6.08696
250 2J0V GDP 0.00000003376 0.6501 6.13208
251 2Y8E GNP 0.0000001252 0.50442 6.14525
252 1MKY GDP 0.000000001049 0.70116 6.19835
253 4RD0 GDP 0.00000003788 0.6691 6.19835
254 2QN6 GDP 0.000000004503 0.65644 6.19835
255 1JWY GDP 0.0000001398 0.62932 6.19835
256 5CK5 GDP 0.00000006048 0.61184 6.19835
257 1F9V ADP 0.000003725 0.50882 6.19835
258 3FVQ ATP 0.00008413 0.50778 6.19835
259 1JWY ADP 0.00007668 0.49643 6.19835
260 3T34 GDP 0.000001265 0.49448 6.19835
261 5FTB ANP 0.0000539 0.49059 6.19835
262 4U00 ADP 0.000001345 0.48691 6.19835
263 5FHD ADP ALF 0.00003973 0.45225 6.19835
264 3WQT ANP 0.01089 0.41123 6.19835
265 4KAX GTP 0.00000006296 0.65861 6.21118
266 4QM7 GTP 0.0000131 0.5213 6.43275
267 1LVG ADP 0.000004471 0.51535 6.56566
268 4KFU ACP 0.000003889 0.50631 6.60377
269 1AZT GSP 0.0000002248 0.64764 6.61157
270 3NHB ADP 0.00001301 0.56246 6.61157
271 3FWY ADP 0.00002573 0.52694 6.61157
272 1ION ADP 0.0001191 0.49056 6.61157
273 2BIF ANP 0.0009961 0.47527 6.61157
274 2BIF SIN 0.001625 0.47527 6.61157
275 1NY5 ADP 0.0005645 0.46428 6.61157
276 1CS4 GSP 0.000001025 0.4611 6.61157
277 1CLU DBG 0.00000001295 0.43218 6.62651
278 3WXM GTP 0.0000006662 0.61768 6.64894
279 5H56 TYD 0.00003718 0.54104 6.66667
280 5H56 ADP 0.00003718 0.54104 6.66667
281 5MVR ADP 0.000005245 0.53895 6.79012
282 1L2T ATP 0.00007485 0.41628 6.80851
283 3TMK T5A 0.00005154 0.53231 6.94444
284 2EW1 GNP 0.0000001363 0.64554 6.96517
285 2FH5 GTP 0.00000009164 0.64783 7.00935
286 2FFQ GSP 0.0000001155 0.65694 7.01754
287 4HDO GNP 0.000000177 0.64795 7.02479
288 5FG3 GDP 0.00000003962 0.61808 7.02479
289 4HSE ADP 0.00004207 0.50837 7.02479
290 3Q9L ATP 0.00007986 0.50396 7.02479
291 3QXC ATP 0.0002305 0.49705 7.02479
292 1R6B ADP 0.0001092 0.4894 7.02479
293 5I34 GDP 0.0001335 0.48541 7.02479
294 3VX3 ADP 0.0004282 0.47218 7.02479
295 1YQT ADP 0.00004362 0.46502 7.02479
296 1G3M PCQ 0.01055 0.42984 7.02479
297 1X6V ADP 0.00002269 0.4132 7.02479
298 4WEI GLC GAL 0.0144 0.40895 7.02479
299 1YZQ GNP 0.0000001085 0.65825 7.05882
300 2RGX AP5 0.00005174 0.55036 7.28155
301 5KUT GDP 0.0000000002986 0.74411 7.40741
302 1SVK ALF GDP 0.00000004407 0.68459 7.43802
303 1ZCB GDP 0.00000003195 0.6813 7.43802
304 1Y3A GDP 0.00000003855 0.67173 7.43802
305 1TAD GDP 0.0000001218 0.66064 7.43802
306 1BH2 GSP 0.0000001329 0.65879 7.43802
307 4DCT GDP 0.00000005865 0.63912 7.43802
308 3AB3 GDP 0.0000001552 0.63701 7.43802
309 2OM2 GDP 0.00000004418 0.56789 7.43802
310 1FQJ GDP 0.00000006812 0.53411 7.43802
311 1FQK GDP 0.0000002176 0.52082 7.43802
312 3COB ADP 0.0000006211 0.51889 7.43802
313 2Q2Y MKR 0.0002109 0.51562 7.43802
314 2Q2Y ADP 0.0002344 0.51456 7.43802
315 4PFO ADP 0.00009682 0.51339 7.43802
316 1TAD ALF 0.0000001218 0.48128 7.43802
317 2ODE ALF GDP 0.0000001125 0.48082 7.43802
318 3DKP ADP 0.000322 0.46025 7.43802
319 1W7J ADP BEF 0.0001016 0.45908 7.43802
320 5VGR GDP 0.0007581 0.42431 7.43802
321 2D2F ADP 0.00005783 0.419 7.43802
322 4ITM ATP 0.01219 0.41197 7.43802
323 1G7C 5GP 0.0000004294 0.5885 7.44681
324 5KSZ GCP 0.00000009117 0.61301 7.54717
325 2ZEJ GDP 0.0000000341 0.6826 7.6087
326 3Q85 GNP 0.000000009699 0.6592 7.69231
327 3Q72 GNP 0.0000000009407 0.68487 7.83133
328 3W5J GDP 0.00000008951 0.54806 7.84314
329 1YRB GDP 0.00000002754 0.66207 7.85124
330 2G77 GDP 0.00000004197 0.59145 7.85124
331 1WDT GTP 0.0000008199 0.53068 7.85124
332 1FP6 ADP 0.00006061 0.50689 7.85124
333 1P72 ADP 0.0003073 0.49914 7.85124
334 4IEE AGS 0.000165 0.49398 7.85124
335 1FNN ADP 0.000009174 0.48933 7.85124
336 4KVA GTP 0.00000003415 0.43231 7.85124
337 4ZG4 VO4 ADP 0.0001218 0.42201 7.85124
338 1EJ4 M7G 0.01396 0.40098 7.89474
339 5KDO GDP 0.00000007316 0.56042 8.10811
340 1GOT GDP 0.0000001082 0.64745 8.21918
341 1OE0 TTP 0.0002579 0.49469 8.26087
342 1D2E GDP 0.00000006925 0.64348 8.26446
343 1W0J ADP 0.00001983 0.52942 8.26446
344 2QZ4 ADP 0.00005069 0.50766 8.26446
345 5X40 ACP 0.0001904 0.49529 8.26446
346 1W0J ADP BEF 0.0002517 0.48303 8.26446
347 4GBM A3P 0.0003698 0.48151 8.26446
348 4XGU ADP 0.00004175 0.47769 8.26446
349 4LC1 GDP 0.00000009635 0.63923 8.30861
350 3CX8 GSP 0.00000008222 0.66898 8.37438
351 1ZD9 GDP 0.00000005308 0.5762 8.51064
352 2XTN GTP 0.000008568 0.55963 8.54701
353 5DI3 GNP 0.0000001266 0.53542 8.64865
354 3E70 GDP 0.000004253 0.55394 8.67769
355 5I0H ADP BEF 0.00008939 0.50654 8.67769
356 5IRN ADP 0.00002344 0.49412 8.67769
357 3QKT ANP 0.0003004 0.48778 8.67769
358 1T5C ADP 0.000001721 0.48538 8.67769
359 4JLV ADP 0.0003426 0.45043 8.67769
360 3TBK ANP 0.0006105 0.43923 8.67769
361 5J1S ATP 0.0002277 0.40932 8.67769
362 1Y63 ADP 0.00001249 0.52205 8.69565
363 4TMK T5A 0.0005516 0.48801 8.92019
364 5E5U MLI 0.002679 0.43368 9.04523
365 4WZA ACP 0.0002042 0.53616 9.09091
366 4WZA ADP 0.0002042 0.53616 9.09091
367 3RLF ANP 0.00009438 0.50985 9.09091
368 1OXV ANP 0.00001576 0.50465 9.09091
369 2AWN ADP 0.0000007029 0.4779 9.09091
370 5IRC GDP 0.0000001192 0.62888 9.13978
371 3LXR GDP 0.00000002403 0.63673 9.18919
372 1JJV ATP 0.00002539 0.47606 9.2233
373 1KMQ GNP 0.00000006417 0.66116 9.23913
374 2PL3 ADP 0.0002118 0.46105 9.32203
375 1CXZ GSP 0.00000004715 0.66458 9.34066
376 1UKZ ADP 0.0001697 0.51341 9.35961
377 3DOE GTP 0.00000004048 0.67072 9.375
378 2NGR GDP 0.00000007059 0.63544 9.42408
379 1A4R GDP 0.0000001777 0.63114 9.42408
380 1GRN GDP 0.0000001727 0.62847 9.42408
381 4ITR GDP 0.0000002878 0.6213 9.42408
382 1A4R GNH 0.0000002952 0.6176 9.42408
383 3IIJ ADP 0.000004166 0.54348 9.44444
384 4XOI GTP 0.00000007625 0.52024 9.44444
385 2WMO GTP 0.00000006 0.64263 9.47368
386 1NRJ GTP 0.0000005129 0.61248 9.49367
387 2PEZ DAT 0.00002067 0.55708 9.49721
388 3GJ0 GDP 0.00000006152 0.64838 9.50226
389 3GJ8 GDP 0.00000008337 0.63213 9.50226
390 3GJ5 GDP 0.00000009457 0.62962 9.50226
391 3GJ7 GDP 0.0000000534 0.62735 9.50226
392 3GJ3 GDP 0.00000006772 0.62283 9.50226
393 4NCN GTP 0.0000001455 0.64417 9.50413
394 4TMZ GSP 0.000000153 0.64313 9.50413
395 2NCD ADP 0.000001606 0.60754 9.50413
396 4H1V GNP 0.0000005012 0.55428 9.50413
397 1IN4 ADP 0.00009139 0.50371 9.50413
398 4QRH 0O2 0.001539 0.4481 9.52381
399 3WYF GTP 0.0000001232 0.65803 9.58904
400 3M1I GTP 0.0000001475 0.65179 9.58904
401 1KSH GDP 0.00000008408 0.6496 9.67742
402 4HAT GNP 0.00000009145 0.66433 9.72222
403 5BXQ GDP 0.00000004431 0.64469 9.72222
404 3CH5 GDP 0.00000005219 0.64144 9.72222
405 3GJX GTP 0.0000002783 0.63843 9.72222
406 1QF9 C5P 0.00006388 0.53897 9.79381
407 1VG0 GDP 0.00000004352 0.65285 9.91736
408 1VG9 GDP 0.00000003371 0.65013 9.91736
409 5L3W GDP 0.00001486 0.53224 9.91736
410 5N69 ADP 0.00002806 0.49103 9.91736
411 4A4Z ANP 0.005814 0.40627 9.91736
412 4YC7 GNP 0.0000002456 0.63052 9.94475
413 1Z08 GNP 0.0000003074 0.51102 10
414 2X77 GDP 0.0000001323 0.62294 10.0529
415 1Z0F GDP 0.00000001528 0.66587 10.0559
416 5IFS ADP 0.00001413 0.53324 10.1266
417 1Z0K GTP 0.0000001016 0.65162 10.1449
418 2BME GNP 0.0000000982 0.65778 10.2151
419 4TTQ ATP 0.0002086 0.46884 10.2326
420 1B0U ATP 0.0001075 0.49534 10.3053
421 5EE5 GTP 0.0000001131 0.64653 10.3286
422 1PUJ GNP 0.000000003487 0.70374 10.3306
423 5L3V GDP 0.000001194 0.56359 10.3306
424 1SQ5 ADP 0.00004364 0.50764 10.3306
425 4PJ3 ANP 0.0004354 0.44576 10.3306
426 1JI0 ATP 0.00001046 0.56039 10.4167
427 2GCN GDP 0.00000004494 0.66557 10.4478
428 2GCO GNP 0.00000003153 0.66298 10.4478
429 2WIC GNP 0.00000000702 0.68133 10.7438
430 1IBR GNP 0.0000001799 0.64761 10.7438
431 2IS6 ADP 0.0001071 0.48039 10.7438
432 2XAU ADP 0.0003509 0.46891 10.7438
433 5L3S GNP 0.000003882 0.46635 10.7438
434 4FCW ADP 0.0004252 0.46237 10.7438
435 4LJ9 ACP 0.0009577 0.43984 10.7438
436 1MH1 GNP 0.0000001055 0.49824 10.7527
437 1NF3 GNP 0.0000004782 0.48766 10.7692
438 1KAO GDP 0.00000009061 0.64156 10.7784
439 1G4U GDP 0.00000008014 0.56787 10.8696
440 2CJW GDP 0.0000000008009 0.70678 10.9375
441 1G3Q ADP 0.00006707 0.4991 10.9705
442 4B47 GDP 0.00000003506 0.62094 11.157
443 4FRZ ADP 0.000004538 0.50467 11.157
444 4RZ3 ADP 0.0001349 0.49332 11.157
445 1Z2A GDP 0.00000004672 0.53777 11.3095
446 4XSH GSP 0.00000003464 0.58054 11.4155
447 3WYG GTP 0.0000001541 0.6533 11.5385
448 5WRJ A3P 0.003207 0.43838 11.5702
449 1GWN GTP 0.00000008237 0.65002 11.7073
450 3H4S ADP 0.0000007071 0.51628 11.8519
451 1WA5 GTP 0.00000007544 0.4716 11.9318
452 1DS6 GDP 0.00000003125 0.63678 11.9792
453 1I4D GDP 0.00000001848 0.63139 11.9792
454 5MZN ADP 0.0003647 0.48396 11.9835
455 3UIE ANP 0.00002107 0.52524 12
456 4CVN ADP 0.000004827 0.57702 12.0419
457 2HT6 GDP 0.000000001626 0.67497 12.069
458 1Z0A GDP 0.00000001853 0.66616 12.069
459 3TNF GNP 0.0000001662 0.65171 12.069
460 4LHW GNP 0.0000001675 0.50388 12.069
461 3QBT GNP 0.0000001961 0.49978 12.069
462 3SBD GNP 0.0000002872 0.49529 12.2995
463 2ZPA ADP 0.00006657 0.51018 12.3967
464 2W2X GSP 0.00000004756 0.6613 12.4324
465 2A5J GDP 0.00000002199 0.63838 12.5654
466 2QTV GNP 0.0000008409 0.61034 12.8099
467 4P4T GDP 0.0000001007 0.56516 12.8099
468 1VHT BA3 0.0005142 0.46126 12.8099
469 2ZPT A3P 0.00691 0.45173 12.8099
470 2FJU GSP 0.0000002484 0.62736 12.9213
471 1M7B GTP 0.00000005608 0.5591 13.0435
472 4C4P GNP 0.0000000649 0.66906 13.0841
473 4DID GDP 0.00000009162 0.63025 13.1579
474 4D0N GDP 0.00000000519 0.67064 13.2231
475 2BLE 5GP 0.02108 0.40448 13.2231
476 1SVI GDP 0.00000002868 0.62504 13.3333
477 1B7T ADP 0.0002715 0.47405 13.4615
478 3EC1 GDP 0.0000009111 0.58458 14.0496
479 1GP2 GDP 0.0000001729 0.52624 14.0845
480 2A9K GDP 0.00000003049 0.66366 14.4385
481 1WF3 GNP 0.0000001884 0.64664 14.4628
482 5JCP GDP ALF 0.00000003074 0.59749 14.4628
483 1KO8 6PG 0.0001294 0.49661 14.8571
484 5L3R GCP 0.000005455 0.46415 14.876
485 1U8Z GDP 0.000000009284 0.56062 14.881
486 2WJH GDP 0.00000003527 0.64923 15.0602
487 2WJH FLC 0.000002834 0.56542 15.0602
488 2OZE AGS 0.0002124 0.48649 15.1007
489 1KK8 BEF ADP 0.0001745 0.4881 15.1079
490 2GJ8 ALF GDP 0.0000005364 0.47969 15.1163
491 3T1O GDP 0.00000001042 0.67769 15.1515
492 3T12 GDP ALF 0.00000001742 0.56338 15.1515
493 1ZC3 GNP 0.00000001563 0.69901 15.4286
494 1UAD GNP 0.00000007758 0.66272 15.4286
495 5SZH GNP 0.0000001507 0.65134 15.6863
496 1GOJ ADP 0.0000002084 0.66506 15.7025
497 1Z0J GTP 0.00000006056 0.50415 15.8824
498 4D0G GTP 0.00000007322 0.6555 15.942
499 1YVD GNP 0.00000008921 0.65979 15.9763
500 5UWP GNP 0.00000007864 0.66752 16.0839
501 5UWT GNP 0.0000001287 0.65466 16.0839
502 5UWJ GNP 0.0000001105 0.49969 16.0839
503 5UWH GNP 0.0000001353 0.49773 16.0839
504 5DI9 GNP 0.00000007283 0.49769 16.0839
505 5DHF GNP 0.0000001364 0.49734 16.0839
506 5UWU GNP 0.0000001385 0.49593 16.0839
507 5DIF GNP 0.0000001378 0.49592 16.0839
508 5UWQ GNP 0.0000001482 0.49493 16.0839
509 5UWR GNP 0.0000001627 0.49452 16.0839
510 5UWW GNP 0.0000001675 0.49424 16.0839
511 5UWS GNP 0.0000001025 0.49385 16.0839
512 5UWO GNP 0.0000001749 0.49354 16.0839
513 4DKX GDP 0.000000009935 0.68557 16.2037
514 2C04 GCP 0.00003158 0.48192 16.5289
515 5KSP GDP 0.00000002693 0.65459 16.8421
516 4PPF FLC 0.000003393 0.60441 17.7686
517 3LRE ADP 0.000001601 0.48821 17.7686
518 2ZR9 DTP 0.0001413 0.47533 17.7686
519 2ZE7 DST 0.002293 0.44869 17.7686
520 2ZE7 AMP 0.009112 0.4181 17.7686
521 1OW3 GDP 0.00000002706 0.66608 18.1347
522 3GJ4 GDP 0.00000007862 0.6204 18.1818
523 5HPY GDP 0.00000004344 0.65648 18.9189
524 2CE7 ADP 0.00005336 0.50663 19.0083
525 1HE1 GDP 0.0000002158 0.54003 19.2593
526 1HE1 AF3 0.01494 0.40393 19.2593
527 1TX4 ALF GDP 0.0000000653 0.53289 19.774
528 2C5L GTP 0.0000000626 0.66982 20.2312
529 4K81 GTP 0.00000005148 0.67647 20.4678
530 3ZIA ATP 0.0000269 0.51727 20.6349
531 3ZIA ADP 0.00005673 0.50823 20.6349
532 5E95 GDP 0.00000002759 0.60135 20.8333
533 1LFD GNP 0.0000002207 0.64082 20.9581
534 2UZI GTP 0.0000000853 0.66073 21.0843
535 3KUD GDP 0.00000005533 0.65819 21.0843
536 3DDC GNP 0.0000003058 0.63645 21.0843
537 1NVU GTP 0.0000003275 0.635 21.0843
538 1WQ1 GDP 0.0000002207 0.51773 21.0843
539 1NVV GNP 0.0000003407 0.63417 22.8916
540 2VOH CIT 0.004348 0.42243 23.0769
541 3BC1 GNP 0.0000002004 0.64284 23.7288
542 2JAQ DCP 0.002571 0.44126 24.3902
543 2D7D ADP 0.0009071 0.44184 25
544 4ZI2 GNP 0.0000002858 0.52469 25.5639
545 4E03 ADP 0.00002061 0.52256 27.1845
546 2V7Q ATP 0.00002296 0.52353 28
547 2V7Q ADP 0.0001014 0.48163 28
548 3QF7 ANP 0.0003046 0.47914 28
549 2CK3 ANP 0.0002583 0.43346 28
550 2CK3 ADP 0.0002709 0.41016 28
551 4HDQ GNP 0.0000002585 0.63999 34.6154
552 3MD0 GDP 0.000000001878 0.67325 36.7769
553 5UWI GNP 0.0000001246 0.65533 38.8889
554 4HI0 GDP 0.00000002201 0.58097 42.7136
Pocket No.: 2; Query (leader) PDB : 4LPS; Ligand: GDP; Similar sites found: 5
This union binding pocket(no: 2) in the query (biounit: 4lps.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2IL4 COA 0.008984 0.4021 None
2 4NTD FAD 0.03399 0.40163 4.13223
3 1IOW PHY 0.02721 0.40145 4.13223
4 3N39 FMN 0.004766 0.42589 7.84314
5 1QHH ATP 0.008875 0.40413 15.2893
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