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Receptor
PDB id Resolution Class Description Source Keywords
4LRJ 1.62 Å EC: 2.7.11.1 BACTERIAL EFFECTOR NLEH1 KINASE DOMAIN WITH AMPPNP AND MG2+ ESCHERICHIA COLI STRUCTURAL GENOMICS MONTREAL-KINGSTON BACTERIAL STRUCTURAL INITIATIVE BSGI KINASE FOLD BATERIAL EFFECTOR KINASE TR
Ref.: NLEH DEFINES A NEW FAMILY OF BACTERIAL EFFECTOR KIN STRUCTURE V. 22 250 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MG A:303;
A:302;
B:302;
A:304;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
ANP A:301;
B:301;
Valid;
Valid;
none;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4LRJ 1.62 Å EC: 2.7.11.1 BACTERIAL EFFECTOR NLEH1 KINASE DOMAIN WITH AMPPNP AND MG2+ ESCHERICHIA COLI STRUCTURAL GENOMICS MONTREAL-KINGSTON BACTERIAL STRUCTURAL INITIATIVE BSGI KINASE FOLD BATERIAL EFFECTOR KINASE TR
Ref.: NLEH DEFINES A NEW FAMILY OF BACTERIAL EFFECTOR KIN STRUCTURE V. 22 250 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 117 families.
1 4LRJ - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 91 families.
1 4LRJ - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 60 families.
1 4LRJ - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 373
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 AP5 0.802632 0.945205
5 ADP 0.802632 0.972222
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 HEJ 0.772152 0.972222
9 ATP 0.772152 0.972222
10 AT4 0.769231 0.933333
11 AN2 0.769231 0.986111
12 5FA 0.7625 0.972222
13 AQP 0.7625 0.972222
14 M33 0.759494 0.932432
15 MAP 0.752941 0.972973
16 ACP 0.75 0.945946
17 AR6 0.740741 0.945205
18 APR 0.740741 0.945205
19 ACQ 0.73494 0.945946
20 AD9 0.731707 0.945946
21 SAP 0.731707 0.921053
22 AGS 0.731707 0.921053
23 A 0.723684 0.944444
24 AMP 0.723684 0.944444
25 ATF 0.717647 0.933333
26 ADX 0.716049 0.851852
27 CA0 0.716049 0.92
28 6YZ 0.709302 0.945946
29 50T 0.707317 0.932432
30 PRX 0.698795 0.87013
31 ABM 0.696203 0.893333
32 AP2 0.679012 0.933333
33 A12 0.679012 0.933333
34 APC 0.678571 0.933333
35 T99 0.674419 0.933333
36 TAT 0.674419 0.933333
37 A22 0.674157 0.958904
38 SRA 0.670886 0.894737
39 SRP 0.670455 0.883117
40 5AL 0.666667 0.906667
41 A1R 0.659341 0.884615
42 ADQ 0.659341 0.92
43 A3R 0.659341 0.884615
44 3OD 0.648936 0.92
45 BIS 0.648936 0.909091
46 5SV 0.648352 0.82716
47 9X8 0.645161 0.896104
48 OAD 0.645161 0.92
49 25L 0.642105 0.958904
50 AMO 0.641304 0.907895
51 G5P 0.636364 0.897436
52 DLL 0.634409 0.906667
53 AHX 0.634409 0.897436
54 00A 0.634409 0.860759
55 ADV 0.632184 0.907895
56 RBY 0.632184 0.907895
57 ADP PO3 0.632184 0.917808
58 NB8 0.631579 0.897436
59 25A 0.630435 0.945205
60 OOB 0.630435 0.906667
61 8QN 0.630435 0.906667
62 G3A 0.626263 0.897436
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 TXA 0.614583 0.907895
67 1ZZ 0.614583 0.819277
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 9ZD 0.612903 0.909091
71 9ZA 0.612903 0.909091
72 3UK 0.610526 0.894737
73 SON 0.604651 0.907895
74 ADP ALF 0.604396 0.848101
75 ALF ADP 0.604396 0.848101
76 PR8 0.604167 0.829268
77 B5V 0.604167 0.883117
78 WAQ 0.604167 0.860759
79 4UV 0.6 0.871795
80 GAP 0.6 0.87013
81 PTJ 0.597938 0.873418
82 FYA 0.597938 0.881579
83 VO4 ADP 0.597826 0.906667
84 ADP VO4 0.597826 0.906667
85 LMS 0.597561 0.829268
86 UP5 0.596154 0.896104
87 FA5 0.59596 0.883117
88 YAP 0.59596 0.871795
89 PAP 0.595506 0.958333
90 A4P 0.59434 0.823529
91 XAH 0.59 0.841463
92 4UU 0.588235 0.871795
93 AFH 0.588235 0.8625
94 9SN 0.585859 0.85
95 2A5 0.58427 0.894737
96 T5A 0.583333 0.821429
97 DQV 0.582524 0.932432
98 NAI 0.580952 0.884615
99 B5M 0.58 0.871795
100 B5Y 0.58 0.871795
101 ITT 0.579545 0.917808
102 ATR 0.577778 0.944444
103 OMR 0.575472 0.831325
104 5AS 0.574713 0.781609
105 YLP 0.571429 0.8
106 48N 0.571429 0.873418
107 AP0 0.570093 0.873418
108 4TC 0.570093 0.873418
109 7D3 0.569767 0.881579
110 ADJ 0.568807 0.831325
111 GNP 0.568421 0.922078
112 9GM 0.568421 0.922078
113 DAL AMP 0.568421 0.881579
114 6V0 0.566038 0.873418
115 TXD 0.566038 0.884615
116 DND 0.566038 0.907895
117 NAX 0.566038 0.851852
118 4UW 0.566038 0.839506
119 NXX 0.566038 0.907895
120 XYA 0.565789 0.821918
121 RAB 0.565789 0.821918
122 ADN 0.565789 0.821918
123 AOC 0.564706 0.8
124 7D4 0.561798 0.881579
125 ADP BMA 0.561224 0.894737
126 TXE 0.560748 0.884615
127 TYM 0.560748 0.883117
128 GA7 0.557692 0.883117
129 YLC 0.555556 0.819277
130 YLB 0.555556 0.8
131 139 0.554545 0.851852
132 5N5 0.551282 0.797297
133 JB6 0.55 0.860759
134 LAQ 0.54717 0.819277
135 F2R 0.544643 0.843373
136 MYR AMP 0.544554 0.797619
137 5CD 0.544304 0.783784
138 A4D 0.544304 0.797297
139 80F 0.54386 0.821429
140 7MD 0.542857 0.864198
141 6AD 0.542553 0.886076
142 A2R 0.541667 0.958904
143 UPA 0.541284 0.884615
144 YLA 0.540541 0.8
145 A A 0.54 0.918919
146 BTX 0.539823 0.821429
147 COD 0.539823 0.793103
148 HFD 0.537634 0.921053
149 G5A 0.537634 0.781609
150 3DH 0.535714 0.753247
151 AYB 0.535714 0.790698
152 CNA 0.535714 0.907895
153 BT5 0.535088 0.811765
154 ATP A A A 0.533981 0.905405
155 IOT 0.531532 0.811765
156 MTA 0.53012 0.753247
157 3AM 0.529412 0.90411
158 A3P 0.52809 0.944444
159 PPS 0.526316 0.851852
160 NAD 0.526316 0.906667
161 EP4 0.52439 0.734177
162 7D5 0.52381 0.855263
163 AMP DBH 0.52381 0.87013
164 J7C 0.522727 0.75
165 A5A 0.520833 0.809524
166 EAD 0.520661 0.851852
167 TSB 0.520408 0.821429
168 AHZ 0.518519 0.797619
169 DTA 0.518072 0.766234
170 M2T 0.518072 0.716049
171 A3D 0.517241 0.894737
172 6RE 0.517241 0.740741
173 YLY 0.516949 0.790698
174 SSA 0.515464 0.802326
175 NA7 0.514852 0.933333
176 ARG AMP 0.514019 0.809524
177 AR6 AR6 0.514019 0.893333
178 7MC 0.513514 0.843373
179 A2P 0.511111 0.930556
180 52H 0.510204 0.781609
181 VMS 0.510204 0.790698
182 54H 0.510204 0.790698
183 TYR AMP 0.509434 0.848101
184 TAD 0.509259 0.8625
185 NAQ 0.508333 0.85
186 A3N 0.505618 0.766234
187 AV2 0.505155 0.893333
188 53H 0.50505 0.781609
189 5CA 0.50505 0.802326
190 8X1 0.50505 0.755556
191 ARU 0.504951 0.839506
192 ZID 0.504132 0.894737
193 P1H 0.504 0.831325
194 NAE 0.5 0.871795
195 3AT 0.5 0.945205
196 AVV 0.5 0.873418
197 P5A 0.495146 0.747253
198 NSS 0.49505 0.802326
199 LSS 0.49505 0.764045
200 DSZ 0.49505 0.802326
201 N0B 0.491803 0.8
202 AF3 ADP 3PG 0.491071 0.817073
203 NVA LMS 0.490196 0.755556
204 DAT 0.489362 0.881579
205 IMO 0.488889 0.90411
206 ZAS 0.488636 0.792208
207 FDA 0.488372 0.813953
208 NAJ PZO 0.487395 0.85
209 4TA 0.487179 0.788235
210 LPA AMP 0.486486 0.797619
211 LEU LMS 0.485437 0.755556
212 DTP 0.484536 0.881579
213 V3L 0.484536 0.945205
214 S4M 0.483516 0.651685
215 GJV 0.483516 0.731707
216 DZD 0.483051 0.8625
217 2AM 0.482759 0.917808
218 5AD 0.481013 0.726027
219 GSU 0.480769 0.781609
220 KAA 0.480769 0.755556
221 NDE 0.480315 0.907895
222 M24 0.479339 0.851852
223 MAO 0.478261 0.761905
224 NEC 0.477778 0.727273
225 DSH 0.477778 0.707317
226 FAS 0.477273 0.831325
227 FAD 0.477273 0.831325
228 RGT 0.476636 0.933333
229 9K8 0.47619 0.698925
230 G A A A 0.474576 0.85
231 0WD 0.474576 0.897436
232 FNK 0.474074 0.786517
233 5X8 0.473684 0.74359
234 6FA 0.473282 0.821429
235 NDC 0.472868 0.85
236 FB0 0.472868 0.786517
237 YSA 0.472222 0.781609
238 7DD 0.468085 0.958333
239 OVE 0.466667 0.881579
240 MHZ 0.463158 0.701149
241 8PZ 0.462963 0.802326
242 A G 0.462185 0.860759
243 AMP NAD 0.462185 0.881579
244 A3G 0.461538 0.779221
245 NAJ PYZ 0.459677 0.809524
246 6C6 0.459184 0.858974
247 SFG 0.458333 0.730769
248 U A G G 0.458333 0.860759
249 7D7 0.45679 0.723684
250 128 0.45614 0.8
251 SFD 0.455224 0.736842
252 6IA 0.454545 0.817073
253 DDS 0.454545 0.855263
254 GDP 0.454545 0.896104
255 ODP 0.453782 0.886076
256 NJP 0.453782 0.921053
257 7DT 0.453608 0.958333
258 A7D 0.452632 0.75641
259 Z5A 0.452381 0.802326
260 WSA 0.452174 0.790698
261 U A 0.45082 0.884615
262 7C5 0.45045 0.797468
263 FAY 0.449275 0.841463
264 NDP 0.449153 0.897436
265 SA8 0.44898 0.690476
266 A5D 0.44898 0.766234
267 71V 0.446809 0.884615
268 GGZ 0.446602 0.804878
269 RFL 0.446043 0.802326
270 2SA 0.445545 0.907895
271 SAI 0.444444 0.716049
272 GP3 0.444444 0.897436
273 SAH 0.444444 0.725
274 PO4 PO4 A A A A PO4 0.443396 0.878378
275 A A A 0.443396 0.881579
276 4YB 0.442478 0.764045
277 SMM 0.441176 0.670455
278 S7M 0.441176 0.674419
279 GTP 0.441176 0.896104
280 Y3J 0.440476 0.706667
281 SAM 0.44 0.674419
282 649 0.439655 0.747253
283 12D 0.438596 0.809524
284 A3S 0.4375 0.789474
285 NPW 0.436975 0.864198
286 GCP 0.436893 0.873418
287 AAT 0.435644 0.690476
288 GNH 0.435644 0.909091
289 EEM 0.435644 0.674419
290 ETB 0.435484 0.813953
291 DCA 0.435484 0.804598
292 N6P 0.433962 0.890411
293 NZQ 0.433333 0.886076
294 TXP 0.433333 0.897436
295 PGS 0.43299 0.860759
296 APU 0.432203 0.871795
297 PUA 0.432 0.8625
298 62F 0.431655 0.841463
299 F2N 0.431507 0.795455
300 DA 0.430108 0.855263
301 D5M 0.430108 0.855263
302 J7V 0.429688 0.813953
303 NIA 0.428571 0.848101
304 COA 0.428571 0.804598
305 6K6 0.428571 0.905405
306 A3T 0.428571 0.8
307 0T1 0.428571 0.804598
308 P5F 0.427586 0.804598
309 AAM 0.425532 0.944444
310 0UM 0.424528 0.682353
311 8Q2 0.423729 0.775281
312 G1R 0.423077 0.884615
313 AMZ 0.422222 0.891892
314 C2R 0.422222 0.88
315 A U 0.420168 0.848101
316 IDP 0.42 0.894737
317 GSP 0.419048 0.851852
318 30N 0.418605 0.736842
319 CAO 0.418605 0.777778
320 DG1 0.418605 0.897436
321 1DG 0.418605 0.897436
322 COS 0.418605 0.786517
323 AMX 0.418605 0.813953
324 TM1 0.418182 0.797619
325 A6D 0.416667 0.746988
326 K15 0.416667 0.666667
327 V1N 0.415929 0.893333
328 CMX 0.415385 0.804598
329 SCO 0.415385 0.804598
330 GEK 0.415094 0.719512
331 XNP 0.414634 0.851852
332 NHD 0.414634 0.881579
333 9JJ 0.413793 0.841463
334 AIR 0.413793 0.876712
335 COK 0.413534 0.786517
336 G2R 0.412844 0.8625
337 ACO 0.412214 0.777778
338 FAM 0.412214 0.786517
339 FCX 0.412214 0.777778
340 NAP 0.410853 0.92
341 FA9 0.409396 0.843373
342 SXZ 0.409091 0.694118
343 HAX 0.409091 0.806818
344 TAP 0.407692 0.884615
345 2MC 0.407407 0.752688
346 62X 0.407407 0.651685
347 GKE 0.40708 0.8625
348 GDC 0.40708 0.8625
349 GDD 0.40708 0.8625
350 3KK 0.406015 0.786517
351 FYN 0.406015 0.804598
352 NVA 2AD 0.405941 0.740741
353 NA0 0.40458 0.907895
354 101 0.404255 0.855263
355 G 0.40404 0.883117
356 5GP 0.40404 0.883117
357 HDV 0.403846 0.87013
358 MGP 0.403846 0.8625
359 OXK 0.402985 0.786517
360 MCD 0.402985 0.786517
361 CA6 0.402985 0.714286
362 SOP 0.402985 0.786517
363 3AD 0.402299 0.783784
364 S8M 0.401869 0.78481
365 YE1 0.40146 0.795455
366 NMX 0.4 0.782609
367 7RP 0.4 0.902778
368 2VA 0.4 0.779221
369 1VU 0.4 0.777778
370 CO6 0.4 0.786517
371 CMC 0.4 0.786517
372 6G0 0.4 0.8625
373 GMV 0.4 0.873418
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4LRJ; Ligand: ANP; Similar sites found with APoc: 447
This union binding pocket(no: 1) in the query (biounit: 4lrj.bio2) has 19 residues
No: Leader PDB Ligand Sequence Similarity
1 2VZ6 FEF None
2 4IDT T28 None
3 2QX0 PH2 None
4 2OFV 242 None
5 1RGE 2GP None
6 3ZS7 ATP None
7 2DT9 THR None
8 3OCP CMP None
9 2YJ0 420 None
10 6GIN IR2 1.18343
11 3H9R TAK 1.18343
12 5F90 GLA GAL 1.28205
13 5F90 LMR 1.28205
14 4K33 ACP 1.77515
15 3TII ANP 1.77515
16 3I0O ADP 1.77515
17 5WS9 AMP 1.77515
18 1N07 FMN 1.84049
19 5WO4 B7V 2.36686
20 4Y93 746 2.36686
21 1IA9 ANP 2.36686
22 5FBN 5WF 2.36686
23 1W2D ADP 2.36686
24 3G5D 1N1 2.36686
25 4RFM 3P6 2.36686
26 1W2D 4IP 2.36686
27 4CC6 L5Y 2.36686
28 1Y57 MPZ 2.36686
29 3WLV AZA 2.36686
30 4CS9 AMP 2.36686
31 3VPD ANP 2.36686
32 5G48 1FL 2.36686
33 6CZI 38E 2.67857
34 3UDZ ADP 2.95858
35 6C0T EE4 2.95858
36 4XMF HSM 2.95858
37 5VC5 96M 2.95858
38 5EQY 5RA 2.95858
39 4OCV ANP 2.95858
40 3VRY B43 2.95858
41 6FL8 TIY 2.95858
42 6FL8 ADP 2.95858
43 2HK5 1BM 2.95858
44 5AE9 OKO 2.95858
45 2Y6O 1N1 2.95858
46 4NZN 2OU 2.95858
47 4NZN ANP 2.95858
48 2XOC ADP 2.95858
49 1JPA ANP 2.95858
50 2IO8 ADP 2.95858
51 4YMJ 4EJ 2.95858
52 5DXT 5H5 2.95858
53 6D6L FY4 2.95858
54 3NJQ NJQ 2.95858
55 1H82 GZZ 2.95858
56 1H82 FAD 2.95858
57 3CQL NAG 2.95858
58 6A5K SAM 2.95858
59 4JGP PYR 2.95858
60 2F2U M77 3.5503
61 4WNK 453 3.5503
62 2QLU ADE 3.5503
63 5MY8 RXZ 3.5503
64 5FI4 5XV 3.5503
65 3HAV ATP 3.5503
66 4NFE BEN 3.5503
67 4AT3 LTI 3.5503
68 5IH1 6BQ 3.5503
69 5IH1 GDP 3.5503
70 4QMN DB8 3.5503
71 3VSV XYS 3.5503
72 5A5W GUO 3.5503
73 5H2U 1N1 3.5503
74 3V4S ATP 3.5503
75 5XLA SIA 3.5503
76 3AB4 THR 3.5503
77 3JU6 ARG 3.5503
78 5L2R MLA 3.5503
79 6CZ3 FLJ 3.5503
80 1FWV SGA MAG FUC 3.73134
81 4H3P ANP 3.8674
82 4H3Q ANP 3.8674
83 5BVE 4VG 3.87812
84 3HCH RSM 4.10959
85 5N87 N66 4.14201
86 5EOB 5QQ 4.14201
87 6FYL 3NG 4.14201
88 3X01 AMP 4.14201
89 4CRL C1I 4.14201
90 1TZD ADP 4.14201
91 5CEO 50D 4.14201
92 3KAL ADP 4.14201
93 4OAV ACP 4.14201
94 5EH0 5NW 4.14201
95 4P5Z Q7M 4.14201
96 4IX4 ADP 4.14201
97 4WOV 3SM 4.14201
98 5T9C G3P 4.14201
99 3C1X CKK 4.14201
100 1QY1 PRZ 4.14201
101 5D9G GLU ASN LEU TYR PHE GLN 4.14201
102 3K5I AIR 4.14201
103 3K5I ADP 4.14201
104 1ZZ7 S0H 4.14201
105 1N62 MCN 4.14201
106 5LRT ADP 4.14201
107 1NE6 SP1 4.14201
108 5T96 79J 4.14201
109 6F7L FAD 4.14201
110 2ZMF CMP 4.14201
111 5XLY C2E 4.51128
112 2HFK E4H 4.70219
113 5MW8 ATP 4.73373
114 3PLS ANP 4.73373
115 2XMY CDK 4.73373
116 3NW7 LGV 4.73373
117 6E2O S0L 4.73373
118 4FL3 ANP 4.73373
119 6CGD AKN 4.73373
120 6CGD GNP 4.73373
121 5TO8 7FM 4.73373
122 4NM5 ADP 4.73373
123 3ZRM ZRM 4.73373
124 1K3A ACP 4.73373
125 1O9U ADZ 4.73373
126 1UNH IXM 4.73373
127 4BHN BH9 4.73373
128 3TM0 B31 4.73373
129 3TM0 ANP 4.73373
130 5DZT AMP 4.73373
131 3F7Z 34O 4.73373
132 5KO1 6UY 4.73373
133 3ZJX BOG 4.73373
134 5HES 032 4.73373
135 4AU8 Z3R 4.73373
136 4LH7 1X8 4.73373
137 3DNT ATP 4.73373
138 3O0G 3O0 4.73373
139 2JLD AG1 4.73373
140 4R78 AMP 4.73373
141 1VAY AZA 4.73373
142 5WL1 CUY 5.05051
143 5WL1 D3D 5.05051
144 6C7Y ADP 5.12821
145 2A19 ANP 5.32544
146 4ZS4 ATP 5.32544
147 5JKG 6LF 5.32544
148 5UR1 YY9 5.32544
149 3PDT ADP 5.32544
150 1OBD ATP 5.32544
151 5JFS 6K0 5.32544
152 4WW7 AMP 5.32544
153 4XZ3 ACP 5.32544
154 6E8I PTR 5.32544
155 4I6H 1C8 5.32544
156 5MRH Q9Z 5.32544
157 2VPQ ANP 5.32544
158 4XYM A12 5.32544
159 1YFS ALA 5.32544
160 4TWP AXI 5.32544
161 3GC0 AMP 5.32544
162 4U0I 0LI 5.32544
163 5USZ SKE 5.32544
164 3GC8 B45 5.32544
165 3KYG 5GP 5GP 5.32544
166 2RDE C2E 5.32544
167 4EN4 GT1 5.32544
168 4EN4 GT0 5.32544
169 4EN4 ATP 5.32544
170 1JG3 ADN 5.32544
171 4B0T ADP 5.32544
172 5C1P ADP 5.55556
173 2C94 TSF 5.625
174 5K2M ADP 5.66038
175 2RIF AMP 5.67376
176 4XH0 ADP 5.91716
177 3WO0 ADP 5.91716
178 3WO0 ALA 5.91716
179 3UIM ANP 5.91716
180 6A1G 9OL 5.91716
181 2H8H H8H 5.91716
182 3WVR AMP 5.91716
183 4O4F ATP 5.91716
184 4O4F IHP 5.91716
185 1Z2P I3S 5.91716
186 1Z2P ACP 5.91716
187 3ZV6 NAD 5.91716
188 3ZV6 4HB 5.91716
189 2Q7D ANP 5.91716
190 3CF6 SP1 5.91716
191 1IOW ADP 5.91716
192 1IOW PHY 5.91716
193 2Q4W FAD 5.91716
194 1QHO MAL 5.91716
195 5FQK 6NT 5.91716
196 6MPT C30 5.91716
197 5EXK 5AD 5.91716
198 1OGX EQU 6.10687
199 4L9I 8PR 6.50888
200 5TA6 79D 6.50888
201 6FYV 3NG 6.50888
202 3TXO 07U 6.50888
203 3GNI ATP 6.50888
204 6G33 5ID 6.50888
205 5X8I SQZ 6.50888
206 4AG8 AXI 6.50888
207 5LPB ADP 6.50888
208 3VHE 42Q 6.50888
209 5T8O 76Z 6.50888
210 4ASE AV9 6.50888
211 5LPZ ADP 6.50888
212 4PNI KQQ 6.50888
213 1M0W ANP 6.50888
214 5NM7 GLY 6.50888
215 3D91 REM 6.50888
216 3FC2 IBI 6.50888
217 5JGA 6KC 6.50888
218 4GLW 0XT 6.50888
219 3H0L ADP 6.50888
220 1Q19 SSC 6.50888
221 1PK8 ATP 6.50888
222 4QM9 CYS 6.50888
223 4K39 SAM 6.50888
224 4AVV CD 6.50888
225 3C3N FMN 6.50888
226 4RDL FUC GAL NDG FUC 6.50888
227 4K38 SAM 6.50888
228 4K37 SAM 6.50888
229 3A16 PXO 6.50888
230 3OIX FMN 6.50888
231 5VX9 FUC GAL NAG GAL BGC 6.8323
232 5LI9 ACP 7.10059
233 5LI1 ANP 7.10059
234 3LXK MI1 7.10059
235 1IR3 ANP 7.10059
236 3ALN ANP 7.10059
237 1XJD STU 7.10059
238 6CMJ F6J 7.10059
239 2X2M X2M 7.10059
240 2ZV2 609 7.10059
241 3BU5 ATP 7.10059
242 3KRL KRL 7.10059
243 5CKW ANP 7.10059
244 4DC2 ADE 7.10059
245 2AQX ATP 7.10059
246 3PN1 IVH 7.10059
247 1S68 AMP 7.10059
248 1G51 AMP 7.10059
249 1G51 AMO 7.10059
250 4DP3 NDP 7.10059
251 5IGI GMP 7.10059
252 5IGI ZIT 7.10059
253 1AUX AGS 7.10059
254 4GID 0GH 7.10059
255 2R7K ACP 7.10059
256 2R7K AMZ 7.10059
257 5U98 1KX 7.10059
258 3EKK GS2 7.10059
259 5N1X 8HH 7.62712
260 2QCS ANP 7.69231
261 4OTH DRN 7.69231
262 1RE8 BD2 7.69231
263 2GU8 796 7.69231
264 2BPM 529 7.69231
265 1U59 STU 7.69231
266 4BCM T7Z 7.69231
267 6GUE FB8 7.69231
268 4CFU 2WC 7.69231
269 5LMK 6ZK 7.69231
270 4BCN T9N 7.69231
271 3KMW ATP 7.69231
272 1VJY 460 7.69231
273 2YRX AMP 7.69231
274 4BCQ TJF 7.69231
275 2GZ3 NAP 7.69231
276 3ORQ ADP 7.69231
277 2FB3 GTP 7.69231
278 2FB3 MET 7.69231
279 3IDB ANP 8.07453
280 3TDV GDP 8.28402
281 2VN9 GVD 8.28402
282 2PVF ACP 8.28402
283 5UKL SIX 8.28402
284 4OCJ NDG 8.28402
285 3PVW QRX 8.28402
286 2PUL ACP 8.28402
287 4O1P ANP 8.28402
288 5YK1 ANP 8.28402
289 2V58 LZJ 8.28402
290 5OKT 9XK 8.28402
291 2BMB PMM 8.28402
292 4KBA 1QM 8.28402
293 2WEL K88 8.28402
294 4FE2 ADP 8.28402
295 3RI1 3RH 8.28402
296 4YZC STU 8.28402
297 4FE2 AIR 8.28402
298 3NOJ PYR 8.28402
299 1OIJ AKG 8.28402
300 1T3Q MCN 8.33333
301 3FHI ANP 8.44156
302 5HWV MBN 8.46154
303 1CBK ROI 8.75
304 2WU6 DKI 8.87574
305 3SRV S19 8.87574
306 3SXS PP2 8.87574
307 4F4P 0SB 8.87574
308 1I7L ATP 8.87574
309 5LXT ACP 9.09091
310 5LXT GTP 9.09091
311 1LR8 IHS 9.45946
312 5GZ9 ANP 9.46746
313 1OUK 084 9.46746
314 1PHK ATP 9.46746
315 5HQ0 LZ9 9.46746
316 6GU6 1QK 9.46746
317 4LOO SB4 9.46746
318 2XVD AS6 9.46746
319 5EKO N17 9.46746
320 4UWH JXM 9.46746
321 6DW2 HD4 9.46746
322 1T36 ADP 9.46746
323 1BYG STU 10.0592
324 5C4L SIS 10.0592
325 5C4L 4XR 10.0592
326 3E7O 35F 10.0592
327 1ZY5 ANP 10.0592
328 4DFU QUE 10.0592
329 1VA6 P2S 10.0592
330 1VA6 ADP 10.0592
331 5WBF LAC 10.0592
332 1FFU FAD 10.4294
333 3LXN MI1 10.6509
334 4WB6 ATP 10.6509
335 3BZ3 YAM 10.6509
336 2PYW ADP 10.6509
337 5I35 ANP 10.6509
338 5Y86 HRM 10.6509
339 2BKK ADP 10.6509
340 2QK4 ATP 10.6509
341 4GJ3 0XP 10.6509
342 6BU3 3GK 10.6509
343 5Z21 OXM 10.6509
344 5OOH NAP 10.6509
345 5OOH 9ZZ 10.6509
346 1Y7P RIP 11.2108
347 2F57 23D 11.2426
348 3HMO STU 11.2426
349 3W0O HY0 11.2426
350 3W0O ADP 11.2426
351 2IF8 ADP 11.2426
352 5NKB 8ZT 11.2426
353 4CYI ATP 11.2426
354 5MJA 7O3 11.2426
355 4TVD BGC 11.2426
356 5DBX ANP 11.8343
357 5HCY 60D 11.8343
358 4WB7 ATP 11.8343
359 1CM8 ANP 11.8343
360 2VQD AP2 11.8343
361 4AUA 4AU 11.8343
362 2YW2 ATP 11.8343
363 4PU5 ANP 11.8343
364 3ETH ATP 11.8343
365 4U98 ACP 11.8343
366 5YSS NAD 11.8343
367 4FG8 ATP 12.426
368 4BTK DTQ 12.426
369 4UXL 5P8 12.426
370 6C1S EFV 12.426
371 5ZTN CUR 12.426
372 6ES0 BW8 12.426
373 5VZ0 ADP 12.426
374 3GQI ACP 13.0178
375 1U5R ATP 13.0178
376 5AWM ANP 13.0178
377 4NST ADP 13.0178
378 5EFQ ADP 13.0178
379 5C03 AGS 13.0178
380 1ZTH ADP 13.0178
381 1ZP9 ATP 13.0178
382 4ONA UW1 13.0178
383 1GSA ADP 13.0178
384 5IM3 DTP 13.0178
385 1E4E ADP 13.0178
386 4RF7 ARG 13.0178
387 1RYI FAD 13.0178
388 1RYI GOA 13.0178
389 1ONI BEZ 13.0435
390 1ZEI CRS 13.2075
391 3IGO ANP 13.6095
392 2WEI VGG 13.6095
393 5ZCT ANP 13.6095
394 4ZOH MCN 13.6095
395 4CLI 5P8 14.2012
396 2GQR ADP 14.2012
397 4E1Z 0MX 14.2012
398 3PP0 03Q 14.2012
399 1V0O INR 14.2012
400 2GQS ADP 14.7929
401 3VPC ADP 14.7929
402 2GQS C2R 14.7929
403 5QIN J2V 15.3846
404 4MV1 ADP 15.3846
405 2BD0 NAP 15.3846
406 5Z2L NDP 15.3846
407 4EWH T77 15.9763
408 3HZT J60 15.9763
409 5WNL STU 15.9763
410 3PAK MAN 16.2162
411 5TDF ADP 16.568
412 1MJT ITU 16.568
413 2B9F ADP 17.1598
414 2B9I ADP 17.1598
415 2B9J ADP 17.1598
416 2B9H ADP 17.1598
417 5OES ADP 17.1598
418 2V7O DRN 17.1598
419 4QTB 38Z 17.1598
420 3VOT ADP 17.1598
421 4E93 GUI 17.1598
422 4IZY 1J2 17.7515
423 4GYI ADP 17.7515
424 4UX9 ANP 17.7515
425 1TQP ATP 18.9349
426 2HGS ADP 18.9349
427 4NG2 OHN 19.0217
428 6G9I CXX 19.0476
429 6EZ6 C5Z 19.5266
430 2GOO NDG 19.8473
431 3TTI KBI 20.7101
432 4WHZ 3NL 20.7101
433 3PTG 932 20.7101
434 3E8N VRA 22.4852
435 3E8N ATP 22.4852
436 3SLS ANP 22.4852
437 5U6C 7YS 23.0769
438 4OYA 1VE 23.6686
439 3VPB ADP 26.7857
440 4Y85 499 27.2189
441 6GQM F8H 27.8107
442 2CSN CKI 29.5858
443 4PZ6 GMP 29.5858
444 5OLK DTP 30.1775
445 3LQV ADE 30.4348
446 4AZW ATP 32.5444
447 4Q5H ANP 39.645
Pocket No.: 2; Query (leader) PDB : 4LRJ; Ligand: ANP; Similar sites found with APoc: 89
This union binding pocket(no: 2) in the query (biounit: 4lrj.bio1) has 19 residues
No: Leader PDB Ligand Sequence Similarity
1 3ZO7 K6H None
2 5LJB RTL None
3 2ARC ARA 1.21951
4 5ZM4 9FU 1.77515
5 2CDO GAL AAL GAL AAL GAL AAL 1.875
6 1F2U ATP 2.02703
7 5EZU MYR 2.24719
8 1OS7 AKG 2.36686
9 1OIK AKG 2.36686
10 5ML3 DL3 2.68456
11 1OPK P16 3.5503
12 3GF4 FAD 3.5503
13 3GF4 UPG 3.5503
14 4G5H NAP 3.5503
15 4G5H UD7 3.5503
16 5N5U 7N8 3.5503
17 2QES ADE 3.5503
18 1DZK PRZ 3.82166
19 1G1T SIA GAL MAG FUC 3.82166
20 5Y4R C2E 4.13793
21 1N62 FAD 4.14201
22 5XFV FMN 4.14201
23 1IUP ALQ 4.14201
24 3QKT ANP 4.14201
25 3HAD NAD 4.14201
26 1NJJ GET 4.14201
27 3ZGJ RMN 4.14201
28 1TMM APC 4.43038
29 1TMM HHR 4.43038
30 2W5P CL8 4.69799
31 5T63 ALA ALA ALA ALA 4.73373
32 1GT4 UNA 5.03145
33 4KVL PLM 5.32544
34 1CKN GTP 5.32544
35 5BWD FUM 5.32544
36 1OX5 1PR 5.32544
37 2CFM AMP 5.32544
38 5DOZ NDP 5.32544
39 3L24 GOA 5.32544
40 2ZYI STE 5.32544
41 2CBT TH2 5.35714
42 5C1P DAL DAL 5.55556
43 2Z3U CRR 5.91716
44 2D3N GLC GLC GLC 5.91716
45 1VBH PEP 5.91716
46 5DP2 NAP 5.91716
47 2BKA NDP 6.50888
48 1QG6 NAD 6.50888
49 4X3R 686 6.50888
50 1UYY BGC BGC 6.87023
51 2CIG 1DG 6.91824
52 5XQL C2E 7.10059
53 4D42 W0I 7.10059
54 4D42 NAP 7.10059
55 3NEM AMO 7.10059
56 3HRD MCN 8.125
57 3DGY 2GP 8.24742
58 3WQQ IB3 8.28402
59 3WQQ NDP 8.28402
60 2XZ9 PYR 8.87574
61 4Y4V DAL 8.87574
62 4MO2 FDA 8.87574
63 5BJX UDP 9.46746
64 5FPN KYD 9.46746
65 1FFU CDP 10.4294
66 4P83 U5P 10.6509
67 2ART LPA AMP 10.6509
68 4J1Q NDP 11.8343
69 6AA8 NAD 11.8343
70 4MNS 2AX 11.9497
71 1O94 AMP 12.426
72 1EP2 ORO 13.0178
73 2GAG FAD 14.1414
74 2GAG FOA 14.1414
75 3GDN MXN 14.2012
76 5W10 CMP 14.2012
77 2Y88 2ER 14.7929
78 5EVY SAL 16.568
79 3HDY GDU 16.568
80 3HDY FAD 16.568
81 1EBF NAD 17.7515
82 4RYV ZEA 18.7097
83 4RPL 3UC 18.9349
84 3KYF 5GP 5GP 19.5266
85 1YRO UDP 21.1382
86 5ETR APC 23.6025
87 5ETR 5RW 23.6025
88 4CSV STI 23.6686
89 1LNX URI 37.037
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