Receptor
PDB id Resolution Class Description Source Keywords
4LWU 1.14 Å EC: 6.3.2.- THE 1.14A CRYSTAL STRUCTURE OF HUMANIZED XENOPUS MDM2 WITH R XENOPUS LAEVIS MDM2 SPIROINDOLINONE E3 UBIQUITIN LIGASE P53 NUCLEUS LILIGASE INHIBITOR COMPLEX
Ref.: DISCOVERY OF POTENT AND SELECTIVE SPIROINDOLINONE M INHIBITOR, RO8994, FOR CANCER THERAPY. BIOORG.MED.CHEM. V. 22 4001 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
20U A:201;
Valid;
none;
ic50 = 0.005 uM
583.481 C30 H29 Cl2 F N4 O3 CC(C)...
SO4 A:202;
Invalid;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4LWU 1.14 Å EC: 6.3.2.- THE 1.14A CRYSTAL STRUCTURE OF HUMANIZED XENOPUS MDM2 WITH R XENOPUS LAEVIS MDM2 SPIROINDOLINONE E3 UBIQUITIN LIGASE P53 NUCLEUS LILIGASE INHIBITOR COMPLEX
Ref.: DISCOVERY OF POTENT AND SELECTIVE SPIROINDOLINONE M INHIBITOR, RO8994, FOR CANCER THERAPY. BIOORG.MED.CHEM. V. 22 4001 2014
Members (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 34 families.
1 4LWU ic50 = 0.005 uM 20U C30 H29 Cl2 F N4 O3 CC(C)(C)C[....
2 4LWV ic50 = 7 nM 20W C29 H29 Cl2 F N4 O4 S CC(C)(C)C[....
3 4J74 Kd = 26 uM I18 C16 H14 Cl2 N2 CC1=N[C@H]....
4 4IPF ic50 = 18 nM 1F0 C38 H48 Cl2 N4 O4 S CCOc1cc(cc....
5 4J7D Kd = 20 uM I31 C29 H32 Cl2 N2 O CCOc1cc(cc....
6 4J3E ic50 = 0.088 uM NUT C30 H30 Cl2 N4 O4 CC(C)Oc1cc....
7 4JSC ic50 = 56 nM 1OY C27 H31 Cl2 F2 N3 O3 CC(C)(C)C[....
8 4JRG ic50 = 196 nM I09 C27 H33 Cl2 N3 O3 CC(C)(C)C[....
9 4J7E Kd = 14 uM I29 C27 H34 Cl2 N4 O3 S CC1=N[C@@]....
10 4LWT ic50 = 3.9 uM 20Q C22 H22 Cl2 N2 O2 CC(=O)N1CC....
70% Homology Family (54)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 23 families.
1 3JZK ic50 = 1.23 uM YIN C24 H16 Br2 N4 O c1ccc2c(c1....
2 4JV7 ic50 = 1 uM 1MN C24 H21 Br2 N O2 CN1[C@@H](....
3 4JVR ic50 = 9.4 nM 1MT C25 H29 Cl2 F N4 O2 CC(C)(C)C[....
4 5LN2 ic50 = 0.13 nM 6ZT C32 H34 Cl2 N4 O3 Cc1cc(ccc1....
5 4ZFI Kd = 0.5 uM 4NJ C27 H21 Cl3 N2 O2 CN1C(=O)C(....
6 4ZYF Ki = 1.3 nM 4T4 C38 H47 Cl N4 O4 CC(C)Oc1cc....
7 4DIJ ic50 = 0.03 uM BLF C31 H29 Cl2 N5 O2 c1ccc(cc1)....
8 4ZYI ic50 = 0.008 uM 4TH C33 H34 Cl N3 O3 CC[C@@H](C....
9 5HMH ic50 = 0.007 uM 62R C35 H38 F6 N4 O6 S CCC[C@@H]1....
10 4OAS Kd = 0.045 nM 2SW C28 H35 Cl2 N O5 S CC[C@@H](C....
11 4ERF ic50 = 1.1 nM 0R3 C25 H29 Cl2 N O4 CC[C@@H]([....
12 4ZYC ic50 = 0.38 uM 4SS C28 H28 Cl N5 O4 CCOc1cc2c(....
13 4OCC ic50 = 2 nM 2TZ C26 H31 Cl2 N O6 S CC[C@@H](C....
14 3LBL Ki = 36 nM MI6 C29 H35 Cl2 F N4 O3 CC(C)(C)C[....
15 4MDN Ki = 0.6 uM Y30 C30 H29 Cl2 N3 O5 CC(C)(C)NC....
16 5HMI ic50 = 0.015 uM 62T C33 H36 F6 N4 O5 S CCC[C@@H]1....
17 4MDQ Ki = 1.2 uM 28W C24 H28 Cl N5 O5 CC(C)C[C@@....
18 4HG7 ic50 = 90 nM NUT C30 H30 Cl2 N4 O4 CC(C)Oc1cc....
19 3W69 ic50 = 8.3 nM LTZ C36 H43 Cl2 N5 O3 S CC[C@@H]1C....
20 4OQ3 ic50 = 0.008 uM 2V8 C24 H18 Cl2 N2 O2 Cc1cccc(c1....
21 4JV9 ic50 = 1.8 uM 1MO C24 H21 Cl2 N O2 CN1[C@@H](....
22 4QOC ic50 = 0.12 nM 35T C29 H34 Cl2 N2 O5 S C[C@@]1(C[....
23 4OGV ic50 = 9 nM 2U7 C26 H31 Cl2 N O6 S CC[C@@H](C....
24 4ZGK Kd = 3.1 uM 4NX C26 H18 Cl3 N O3 c1cc(ccc1C....
25 4OBA ic50 = 0.4 nM 2TW C27 H31 Cl2 N O6 S CC(C)(C)S(....
26 4JVE ic50 = 0.086 uM 1MQ C28 H24 Cl2 F N O4 C/C=C/[C@H....
27 4JWR ic50 = 0.61 uM 1MY C22 H23 Cl2 N O5 CC[C@@H](C....
28 4ERE ic50 = 4.2 nM 0R2 C27 H31 Cl2 N O5 CC[C@@H](C....
29 4QO4 ic50 = 0.005 uM 35S C31 H32 Cl2 N2 O3 CC[C@@H](c....
30 4LWU ic50 = 0.005 uM 20U C30 H29 Cl2 F N4 O3 CC(C)(C)C[....
31 4LWV ic50 = 7 nM 20W C29 H29 Cl2 F N4 O4 S CC(C)(C)C[....
32 4J74 Kd = 26 uM I18 C16 H14 Cl2 N2 CC1=N[C@H]....
33 4IPF ic50 = 18 nM 1F0 C38 H48 Cl2 N4 O4 S CCOc1cc(cc....
34 4J7D Kd = 20 uM I31 C29 H32 Cl2 N2 O CCOc1cc(cc....
35 4J3E ic50 = 0.088 uM NUT C30 H30 Cl2 N4 O4 CC(C)Oc1cc....
36 4JSC ic50 = 56 nM 1OY C27 H31 Cl2 F2 N3 O3 CC(C)(C)C[....
37 4JRG ic50 = 196 nM I09 C27 H33 Cl2 N3 O3 CC(C)(C)C[....
38 4J7E Kd = 14 uM I29 C27 H34 Cl2 N4 O3 S CC1=N[C@@]....
39 4LWT ic50 = 3.9 uM 20Q C22 H22 Cl2 N2 O2 CC(=O)N1CC....
40 5J7F - 6GG C35 H33 Cl2 F N4 O5 c1cc(ccc1C....
41 4HBM Kd = 8.2 nM 0Y7 C23 H25 Cl2 N O4 CC[C@@H](C....
42 3TU1 Ki = 0.25 uM 07G C23 H21 Cl F2 N3 O4 CC(C)(C)NC....
43 2AXI ic50 = 140 nM PRO PHE GLU 6CW LEU ASP TRP GLU PHE DPR n/a n/a
44 5J7G - 6GG C35 H33 Cl2 F N4 O5 c1cc(ccc1C....
45 1T4F - ARG PHE MET ASP TYR TRP GLU GLY LEU n/a n/a
46 2GV2 ic50 = 5 nM ACE PHE MET AIB PM3 6CW GLU 1AC LEU n/a n/a
47 5HMK ic50 = 0.04 uM 62Q C35 H38 F6 N4 O5 CCC[C@@H]1....
48 5TRF Ki = 0.88 nM 7HC C29 H34 Cl2 F N3 O3 CC(C)(C)C[....
49 4WT2 Kd = 39 pM 3UD C37 H41 Cl2 F N2 O7 S C[C@@]1(C[....
50 4OGT ic50 = 0.1 nM 2U6 C33 H36 Cl2 N2 O6 S C[C@]1(C(=....
51 1RV1 ic50 = 0.14 uM IMZ C31 H34 Br2 N4 O4 CCOc1cc(cc....
52 4ODF ic50 = 0.1 nM 2U1 C33 H36 Cl2 N2 O6 S C[C@@]1(C(....
53 4ODE ic50 = 0.1 nM 2U0 C33 H37 Cl2 F N2 O5 S2 C[C@@]1(C[....
54 4OGN ic50 = 0.1 nM 2U5 C34 H38 Cl2 N2 O5 S C[C@@]1(C[....
50% Homology Family (57)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 18 families.
1 3JZK ic50 = 1.23 uM YIN C24 H16 Br2 N4 O c1ccc2c(c1....
2 4JV7 ic50 = 1 uM 1MN C24 H21 Br2 N O2 CN1[C@@H](....
3 4JVR ic50 = 9.4 nM 1MT C25 H29 Cl2 F N4 O2 CC(C)(C)C[....
4 5LN2 ic50 = 0.13 nM 6ZT C32 H34 Cl2 N4 O3 Cc1cc(ccc1....
5 4ZFI Kd = 0.5 uM 4NJ C27 H21 Cl3 N2 O2 CN1C(=O)C(....
6 4ZYF Ki = 1.3 nM 4T4 C38 H47 Cl N4 O4 CC(C)Oc1cc....
7 4DIJ ic50 = 0.03 uM BLF C31 H29 Cl2 N5 O2 c1ccc(cc1)....
8 4ZYI ic50 = 0.008 uM 4TH C33 H34 Cl N3 O3 CC[C@@H](C....
9 5HMH ic50 = 0.007 uM 62R C35 H38 F6 N4 O6 S CCC[C@@H]1....
10 4OAS Kd = 0.045 nM 2SW C28 H35 Cl2 N O5 S CC[C@@H](C....
11 4ERF ic50 = 1.1 nM 0R3 C25 H29 Cl2 N O4 CC[C@@H]([....
12 4ZYC ic50 = 0.38 uM 4SS C28 H28 Cl N5 O4 CCOc1cc2c(....
13 4OCC ic50 = 2 nM 2TZ C26 H31 Cl2 N O6 S CC[C@@H](C....
14 3LBL Ki = 36 nM MI6 C29 H35 Cl2 F N4 O3 CC(C)(C)C[....
15 4MDN Ki = 0.6 uM Y30 C30 H29 Cl2 N3 O5 CC(C)(C)NC....
16 5HMI ic50 = 0.015 uM 62T C33 H36 F6 N4 O5 S CCC[C@@H]1....
17 4MDQ Ki = 1.2 uM 28W C24 H28 Cl N5 O5 CC(C)C[C@@....
18 4HG7 ic50 = 90 nM NUT C30 H30 Cl2 N4 O4 CC(C)Oc1cc....
19 3W69 ic50 = 8.3 nM LTZ C36 H43 Cl2 N5 O3 S CC[C@@H]1C....
20 4OQ3 ic50 = 0.008 uM 2V8 C24 H18 Cl2 N2 O2 Cc1cccc(c1....
21 4JV9 ic50 = 1.8 uM 1MO C24 H21 Cl2 N O2 CN1[C@@H](....
22 4QOC ic50 = 0.12 nM 35T C29 H34 Cl2 N2 O5 S C[C@@]1(C[....
23 4OGV ic50 = 9 nM 2U7 C26 H31 Cl2 N O6 S CC[C@@H](C....
24 4ZGK Kd = 3.1 uM 4NX C26 H18 Cl3 N O3 c1cc(ccc1C....
25 4OBA ic50 = 0.4 nM 2TW C27 H31 Cl2 N O6 S CC(C)(C)S(....
26 4JVE ic50 = 0.086 uM 1MQ C28 H24 Cl2 F N O4 C/C=C/[C@H....
27 4JWR ic50 = 0.61 uM 1MY C22 H23 Cl2 N O5 CC[C@@H](C....
28 4ERE ic50 = 4.2 nM 0R2 C27 H31 Cl2 N O5 CC[C@@H](C....
29 4QO4 ic50 = 0.005 uM 35S C31 H32 Cl2 N2 O3 CC[C@@H](c....
30 4LWU ic50 = 0.005 uM 20U C30 H29 Cl2 F N4 O3 CC(C)(C)C[....
31 4LWV ic50 = 7 nM 20W C29 H29 Cl2 F N4 O4 S CC(C)(C)C[....
32 4J74 Kd = 26 uM I18 C16 H14 Cl2 N2 CC1=N[C@H]....
33 4IPF ic50 = 18 nM 1F0 C38 H48 Cl2 N4 O4 S CCOc1cc(cc....
34 4J7D Kd = 20 uM I31 C29 H32 Cl2 N2 O CCOc1cc(cc....
35 4J3E ic50 = 0.088 uM NUT C30 H30 Cl2 N4 O4 CC(C)Oc1cc....
36 4JSC ic50 = 56 nM 1OY C27 H31 Cl2 F2 N3 O3 CC(C)(C)C[....
37 4JRG ic50 = 196 nM I09 C27 H33 Cl2 N3 O3 CC(C)(C)C[....
38 4J7E Kd = 14 uM I29 C27 H34 Cl2 N4 O3 S CC1=N[C@@]....
39 4LWT ic50 = 3.9 uM 20Q C22 H22 Cl2 N2 O2 CC(=O)N1CC....
40 5J7F - 6GG C35 H33 Cl2 F N4 O5 c1cc(ccc1C....
41 4HBM Kd = 8.2 nM 0Y7 C23 H25 Cl2 N O4 CC[C@@H](C....
42 3TU1 Ki = 0.25 uM 07G C23 H21 Cl F2 N3 O4 CC(C)(C)NC....
43 2AXI ic50 = 140 nM PRO PHE GLU 6CW LEU ASP TRP GLU PHE DPR n/a n/a
44 5J7G - 6GG C35 H33 Cl2 F N4 O5 c1cc(ccc1C....
45 1T4F - ARG PHE MET ASP TYR TRP GLU GLY LEU n/a n/a
46 3U15 ic50 = 41 nM 03M C20 H14 Cl F2 N3 O2 Cc1c(ccc2c....
47 3FE7 Kd = 75 nM ACE PHE MET AIB PM3 TRP GLU 1AC LEU NH2 n/a n/a
48 3FEA Kd = 36 nM ACE PHE MET AIB PM3 6CW GLU 1AC LEU NH2 n/a n/a
49 2GV2 ic50 = 5 nM ACE PHE MET AIB PM3 6CW GLU 1AC LEU n/a n/a
50 5HMK ic50 = 0.04 uM 62Q C35 H38 F6 N4 O5 CCC[C@@H]1....
51 5TRF Ki = 0.88 nM 7HC C29 H34 Cl2 F N3 O3 CC(C)(C)C[....
52 4WT2 Kd = 39 pM 3UD C37 H41 Cl2 F N2 O7 S C[C@@]1(C[....
53 4OGT ic50 = 0.1 nM 2U6 C33 H36 Cl2 N2 O6 S C[C@]1(C(=....
54 1RV1 ic50 = 0.14 uM IMZ C31 H34 Br2 N4 O4 CCOc1cc(cc....
55 4ODF ic50 = 0.1 nM 2U1 C33 H36 Cl2 N2 O6 S C[C@@]1(C(....
56 4ODE ic50 = 0.1 nM 2U0 C33 H37 Cl2 F N2 O5 S2 C[C@@]1(C[....
57 4OGN ic50 = 0.1 nM 2U5 C34 H38 Cl2 N2 O5 S C[C@@]1(C[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: 20U; Similar ligands found: 6
No: Ligand ECFP6 Tc MDL keys Tc
1 20U 1 1
2 1MT 0.737374 0.903226
3 7HC 0.715686 0.850746
4 MI6 0.637168 0.746667
5 20W 0.491935 0.852941
6 1OY 0.4 0.694444
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4LWU; Ligand: 20U; Similar sites found: 175
This union binding pocket(no: 1) in the query (biounit: 4lwu.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4YV5 SVR 0.0005282 0.53666 None
2 1JQ9 PHE LEU SER TYR LYS 0.0001686 0.50772 None
3 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 0.0006568 0.49357 None
4 2QHD DAO 0.001094 0.48508 None
5 1S8G DAO 0.0002279 0.4636 None
6 2E2R 2OH 0.00164 0.46236 None
7 2XSU PIE 0.001247 0.45982 None
8 3KMZ EQO 0.001278 0.45775 None
9 1PZO CBT 0.003159 0.453 None
10 2EV1 OLA 0.001156 0.45296 None
11 4ZBR DIF 0.004619 0.43795 None
12 4ZBR NPS 0.004926 0.43533 None
13 3WYJ H78 0.01582 0.43527 None
14 4I67 G G G RPC 0.004299 0.42322 None
15 2OBD PCW 0.008369 0.42291 None
16 3E2M E2M 0.02599 0.41876 None
17 3B6C SDN 0.0006654 0.41724 None
18 3VHZ L2P GLC MAN SGA 0.02023 0.41658 None
19 3EWK FAD 0.005641 0.41536 None
20 1HN4 MJI 0.03892 0.41524 None
21 3E85 BSU 0.02112 0.41199 None
22 4EKQ NPO 0.006212 0.41146 None
23 4RC8 STE 0.01051 0.40812 None
24 4GFD 0YB 0.01144 0.40798 None
25 5B4B LP5 0.0162 0.40778 None
26 4NB5 2JT 0.008474 0.40722 None
27 4GQL R47 0.02463 0.4067 None
28 3QKD HI0 0.01367 0.40584 None
29 5IXH OTP 0.03186 0.40573 None
30 3CH6 311 0.04908 0.40369 None
31 3CH6 NAP 0.04908 0.40369 None
32 5V4R MGT 0.02945 0.40164 None
33 2J07 FAD 0.0276 0.41453 1.17647
34 2J07 HDF 0.0276 0.41453 1.17647
35 5I2E 67D 0.0136 0.42702 2.35294
36 1AV5 AP2 0.004055 0.41986 2.35294
37 4JD3 PLM 0.003748 0.45434 3.52941
38 4JD3 COA 0.003428 0.45434 3.52941
39 1DIG L37 0.01105 0.42068 3.52941
40 1DIG NAP 0.01122 0.41918 3.52941
41 4LAE NAP 0.02424 0.41818 3.52941
42 4LAE 1VM 0.02424 0.41818 3.52941
43 4ZOM 4Q3 0.01074 0.44832 4.70588
44 5IR4 ZPE 0.00487 0.44672 4.70588
45 5IXK 6EW 0.003309 0.4437 4.70588
46 4O6M C5P 0.002494 0.42957 4.70588
47 3C88 ARG ARG GLY CYS NH2 0.01266 0.42945 4.70588
48 3N1S 5GP 0.002189 0.42218 4.70588
49 4KCF AKM 0.006433 0.41976 4.70588
50 3L9R L9R 0.01182 0.41923 4.70588
51 5TIV A3P 0.02665 0.40965 4.70588
52 5U3B 7TD 0.01576 0.40835 4.70588
53 3L9R L9Q 0.02501 0.40326 4.70588
54 3UR0 SVR 0.01829 0.40125 4.70588
55 1DMH LIO 0.004005 0.44997 5.88235
56 1RX0 2MC 0.008096 0.41812 5.88235
57 5K53 STE 0.006213 0.41531 5.88235
58 4I9A NCN 0.006603 0.41025 5.88235
59 3TDC 0EU 0.002725 0.40642 5.88235
60 2C78 PUL 0.04785 0.40559 5.88235
61 2WPX ACO 0.009678 0.40456 5.88235
62 2WOR 2AN 0.0003786 0.40309 5.88235
63 2Q2Y MKR 0.002682 0.48198 7.05882
64 2Q2Y ADP 0.002682 0.48198 7.05882
65 4MNS 2AX 0.00127 0.48087 7.05882
66 1DKF BMS 0.0014 0.44907 7.05882
67 3G9E RO7 0.003408 0.44561 7.05882
68 2JFZ 003 0.009925 0.44322 7.05882
69 5TWO 7MV 0.001782 0.44039 7.05882
70 2J8C U10 0.01417 0.43841 7.05882
71 2J8C SPO 0.01417 0.43841 7.05882
72 2JFZ DGL 0.01258 0.43786 7.05882
73 1FM9 570 0.004882 0.43422 7.05882
74 1RDT 570 0.00407 0.43073 7.05882
75 3H0A D30 0.00985 0.41549 7.05882
76 2HFP NSI 0.008946 0.41302 7.05882
77 2I6A 5I5 0.006618 0.41216 7.05882
78 1NC4 DOF 0.01699 0.4059 7.05882
79 5D59 78M 0.03862 0.40233 7.05882
80 4ANP 3QI 0.02456 0.40023 7.05882
81 3KDU NKS 0.0005927 0.4976 8.23529
82 3FEI CTM 0.00113 0.45525 8.23529
83 3SP6 IL2 0.0008275 0.45366 8.23529
84 1K7L 544 0.001555 0.4521 8.23529
85 4QWT ACD 0.002169 0.44526 8.23529
86 1H9G COA MYR 0.00263 0.44284 8.23529
87 5B0W 22B 0.008546 0.42373 8.23529
88 2P1C GG3 0.00818 0.42209 8.23529
89 1YKI NFZ 0.0139 0.41691 8.23529
90 1M13 HYF 0.01257 0.41559 8.23529
91 5K52 OCD 0.007985 0.41203 8.23529
92 1YKI FMN 0.01496 0.41191 8.23529
93 4DV8 0LX 0.01925 0.40993 8.23529
94 5KAU RHQ 0.007928 0.40855 8.23529
95 2NPA MMB 0.0009465 0.40644 8.23529
96 2EIX FAD 0.01641 0.40621 8.23529
97 2VWA PTY 0.02923 0.40389 8.23529
98 3NRR D16 0.04164 0.40383 8.23529
99 3LXI CAM 0.0202 0.4022 8.23529
100 3NRR NAP 0.03979 0.40166 8.23529
101 1FO0 ILE ASN PHE ASP PHE ASN THR ILE 0.00594 0.44043 9.41177
102 2VBQ BSJ 0.01356 0.41744 9.41177
103 4YSX E23 0.001058 0.41345 9.41177
104 2W90 6PG 0.009602 0.41311 9.41177
105 5F1X ATP 0.01355 0.41278 9.41177
106 2Z7I 742 0.04605 0.41248 9.41177
107 2WZV FMN 0.02058 0.40956 9.41177
108 1GHE ACO 0.01122 0.40839 9.41177
109 4IA6 EIC 0.0005464 0.40225 9.41177
110 2PRG BRL 0.002041 0.43356 10.2273
111 2I0G I0G 0.002371 0.46894 10.5882
112 4OIV XX9 0.001712 0.46617 10.5882
113 5L2J 70E 0.004966 0.4629 10.5882
114 5L2J 6UL 0.005813 0.45801 10.5882
115 5DHU 5A8 0.009015 0.44397 10.5882
116 2AX9 BHM 0.007303 0.43596 10.5882
117 3SCM LGN 0.02897 0.41632 10.5882
118 3BEJ MUF 0.01236 0.40482 10.5882
119 3W54 RNB 0.007881 0.40254 10.5882
120 1M2Z BOG 0.00006719 0.56401 11.7647
121 1NHZ 486 0.0007177 0.46262 11.7647
122 2BJ4 OHT 0.0007342 0.45818 11.7647
123 5EW9 5VC 0.02651 0.43777 11.7647
124 4P6X HCY 0.01468 0.41348 11.7647
125 1AE1 NAP 0.01858 0.4096 11.7647
126 2FXU ATP 0.04499 0.40953 11.7647
127 5F2T PLM 0.01107 0.40367 11.7647
128 1LN1 DLP 0.02349 0.40349 11.7647
129 1EWF PC1 0.03361 0.40279 11.7647
130 5AHS COA 0.02624 0.40223 11.7647
131 1TV5 N8E 0.003963 0.44346 12.9412
132 3DST GRG 0.0144 0.44269 12.9412
133 1UUO BRF 0.009755 0.4422 12.9412
134 1UUO ORO 0.00975 0.44076 12.9412
135 1UUO FMN 0.00975 0.44076 12.9412
136 4ORM 2V6 0.01349 0.4389 12.9412
137 4ORM FMN 0.01349 0.4389 12.9412
138 4ORM ORO 0.01349 0.4389 12.9412
139 2A06 SMA 0.01596 0.41395 12.9412
140 2Q4H AMP 0.0111 0.41302 12.9412
141 3T58 FAD 0.0232 0.40022 12.9412
142 2DYS TGL 0.02454 0.40256 13.0435
143 2DYR TGL 0.02656 0.40087 13.0435
144 4UCC ZKW 0.00456 0.44246 14.1176
145 3CXH SMA 0.006158 0.42523 14.1176
146 3CX5 SMA 0.007365 0.42007 14.1176
147 2IBZ SMA 0.01154 0.4078 14.8649
148 5AAV GW5 0.002566 0.47054 15.2941
149 1YQZ FAD 0.01934 0.4288 15.2941
150 4INI AMP 0.002268 0.42694 15.2941
151 5IVX ARG GLY PRO GLY ARG ALA PHE VAL THR ILE 0.01327 0.42491 15.2941
152 4G8R 96P 0.00983 0.42068 15.2941
153 1RE9 DSO 0.01455 0.406 15.2941
154 3G5N PB2 0.01151 0.44949 16.4706
155 5LIA 6XN 0.04397 0.41299 16.4706
156 3QCQ 3Q0 0.02169 0.43675 17.6471
157 1BUC CAA 0.005519 0.42449 17.6471
158 2QJY SMA 0.006528 0.42256 17.6471
159 4ELG 52I 0.01423 0.4092 17.6471
160 1QF9 C5P 0.02282 0.40734 17.6471
161 1QF9 ADP 0.02282 0.40734 17.6471
162 1QF9 ALF 0.02282 0.40734 17.6471
163 4ELG 52J 0.01841 0.40248 17.6471
164 3QCP FAD 0.006016 0.42424 20
165 3LDW ZOL 0.009353 0.42183 20
166 5LXT GDP 0.04615 0.42075 20
167 5LXT 7AK 0.04447 0.42075 20
168 2FDW D3G 0.01102 0.40814 22.3529
169 4ZE0 VOR 0.00504 0.43355 23.5294
170 3CGD NAD 0.0486 0.41633 23.5294
171 3CGD COA 0.0486 0.41633 23.5294
172 3CGD FAD 0.0486 0.41633 23.5294
173 4OAR 2S0 0.0002133 0.48296 25.8824
174 1SR7 MOF 0.001247 0.4642 25.8824
175 1NF8 BOG 0.0168 0.41141 30.5882
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