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Receptor
PDB id Resolution Class Description Source Keywords
4M37 1.7 Å EC: 2.1.1.- CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI PROTEIN ARGININE METHYLTRANSFERASE 7 COMPLEX WITH ADOHCY TRYPANOSOMA BRUCEI BRUCEI METHYLTRANSFERASE TRANSFERASE
Ref.: STRUCTURAL DETERMINANTS FOR THE STRICT MONOMETHYLAT ACTIVITY BY TRYPANOSOMA BRUCEI PROTEIN ARGININE METHYLTRANSFERASE 7 STRUCTURE 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAH A:401;
Valid;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4M37 1.7 Å EC: 2.1.1.- CRYSTAL STRUCTURE OF TRYPANOSOMA BRUCEI PROTEIN ARGININE METHYLTRANSFERASE 7 COMPLEX WITH ADOHCY TRYPANOSOMA BRUCEI BRUCEI METHYLTRANSFERASE TRANSFERASE
Ref.: STRUCTURAL DETERMINANTS FOR THE STRICT MONOMETHYLAT ACTIVITY BY TRYPANOSOMA BRUCEI PROTEIN ARGININE METHYLTRANSFERASE 7 STRUCTURE 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 60 families.
1 4M37 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 54 families.
1 4M37 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 47 families.
1 4M37 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4M37; Ligand: SAH; Similar sites found with APoc: 896
This union binding pocket(no: 1) in the query (biounit: 4m37.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 2JAH NDP None
2 3EM1 TYD None
3 5C2N NAG None
4 2EWM NAD 0.803213
5 1D4D FAD 1.16618
6 5EZ7 FAD 1.16618
7 3S5W FAD 1.16618
8 1Q7B NAP 1.22951
9 5TS5 FAD 1.45773
10 5JCM ISD 1.45773
11 5JCM FAD 1.45773
12 5JCM NAD 1.45773
13 1YKJ PHB 1.45773
14 1YKJ FAD 1.45773
15 6EL3 NAP 1.45773
16 1SOW NAD 1.52439
17 5MIT FAD 1.52905
18 5MIT NAP 1.52905
19 1OMO NAD 1.5528
20 2JAP NDP 1.61943
21 3CH6 NAP 1.74825
22 3CH6 311 1.74825
23 5E72 SAM 1.74927
24 1G55 SAH 1.74927
25 2IVD FAD 1.74927
26 2YG3 FAD 1.74927
27 1RSG FAD 1.74927
28 2RAB NAD 1.74927
29 4USR FAD 1.74927
30 1YY5 FAD 1.74927
31 2RAB FAD 1.74927
32 1ZK7 FAD 1.74927
33 5KOX RFP 1.74927
34 5KOX FAD 1.74927
35 4D04 NAP 1.74927
36 4D04 FAD 1.74927
37 1PS9 FAD 1.74927
38 2DKH FAD 1.74927
39 2DKH 3HB 1.74927
40 3G5S FAD 1.74927
41 4AT0 FAD 1.74927
42 4DSG FAD 1.74927
43 4DSG UDP 1.74927
44 4XFR CIT 1.74927
45 3WMX NAD 1.74927
46 3L9W GSH 1.74927
47 1BXK NAD 1.74927
48 3L9W AMP 1.74927
49 4GLL NAD 1.78042
50 5L95 AMP 1.79211
51 1VDC FAD 1.8018
52 5K0A FAD 1.81818
53 4O0L NDP 1.81818
54 2GDZ NAD 1.87266
55 5G6U YJM 1.91571
56 5W7K SAH 1.92308
57 3O9Z AKG 1.92308
58 3O9Z NAD 1.92308
59 4RPL FAD 2.04082
60 4RPL 3UC 2.04082
61 5VN0 FAD 2.04082
62 2RGJ FAD 2.04082
63 5VN0 NAI 2.04082
64 4Z24 FAD 2.04082
65 2CDU FAD 2.04082
66 3AYI FAD 2.04082
67 3AYI HCI 2.04082
68 2GMH FAD 2.04082
69 5N0J FAD 2.04082
70 5EB4 FAD 2.04082
71 5XWV 8H6 2.04082
72 4YKG NAD 2.04082
73 2ZXI FAD 2.04082
74 5XWV NDP 2.04082
75 4YKG FAD 2.04082
76 2GN4 NDP 2.04082
77 1YQT ADP 2.04082
78 2CDU ADP 2.04082
79 2GN4 UD1 2.04082
80 1YB5 NAP 2.04082
81 2C5A GDC 2.04082
82 2C5A NAD 2.04082
83 3Q9T FAY 2.04082
84 5N53 8NB 2.05128
85 1ELI PYC 2.05656
86 3B1F NAD 2.06897
87 5JGL SAM 2.07612
88 4YMH SAH 2.08333
89 6FDF SAH 2.09581
90 3C3Y SAH 2.1097
91 2DPM SAM 2.11268
92 1PZG A3D 2.1148
93 4D42 W0I 2.12766
94 4D42 NAP 2.12766
95 1BDB NAD 2.16606
96 1JPA ANP 2.24359
97 2WPB ZZI 2.30263
98 3OID NDP 2.32558
99 5YF1 SFG 2.33236
100 1XDS SAM 2.33236
101 5DNK SAH 2.33236
102 4BV6 FAD 2.33236
103 5BRT FAD 2.33236
104 5BRT CH9 2.33236
105 1LVL FAD 2.33236
106 1Q9I FAD 2.33236
107 1Q9I TEO 2.33236
108 3GF4 UPG 2.33236
109 2B9W FAD 2.33236
110 3GF4 FAD 2.33236
111 4JDR FAD 2.33236
112 3UOY NAP 2.33236
113 3UOY FAD 2.33236
114 5TWB FAD 2.33236
115 1LVL NAD 2.33236
116 1UWK URO 2.33236
117 1UWK NAD 2.33236
118 1FP2 SAH 2.33236
119 5YF1 8V0 2.33236
120 2Y6Q FAD 2.33236
121 2Y6Q I7T 2.33236
122 2XVF FAD 2.33236
123 4Z87 GDP 2.33236
124 5EOW FAD 2.33236
125 1X87 NAD 2.33236
126 3V1U NAD 2.33236
127 5YU3 PRO 2.33236
128 5YU3 NAD 2.33236
129 2VTD LKM 2.33236
130 2YYY NAP 2.33236
131 1T9D P25 2.33236
132 1T9D PYD 2.33236
133 5WKC FAD 2.33236
134 1T9D FAD 2.33236
135 1C0I BE2 2.33236
136 1C0I FAD 2.33236
137 1DLJ NAI 2.33236
138 5OVK NDP 2.34375
139 2WSB NAD 2.3622
140 1CF2 NAP 2.37389
141 4BLW SAH 2.42215
142 4BLW AMP 2.42215
143 5Y1G AKB 2.43902
144 5Y1G NAD 2.43902
145 5Z2L NDP 2.44898
146 1EDO NAP 2.45902
147 1NJR XYL 2.46479
148 5UAV NDP 2.48447
149 5UAV TFB 2.48447
150 6ECT SAM 2.49221
151 3SJU NDP 2.50896
152 4JZ8 CIT 2.52366
153 5O4J 9KH 2.55474
154 5O4J PJL 2.55474
155 5O4J SAH 2.55474
156 2UYQ SAM 2.58065
157 2CUL FAD 2.58621
158 4ITU NAI 2.60223
159 4ITU 1HS 2.60223
160 1VL8 NAP 2.62172
161 3RFV 15L 2.62172
162 3RFV NAI 2.62172
163 4YNU FAD 2.62391
164 4YNU LGC 2.62391
165 5BUK FAD 2.62391
166 3QVP FAD 2.62391
167 4AP3 FAD 2.62391
168 4AP3 NAP 2.62391
169 1H82 FAD 2.62391
170 1H82 GZZ 2.62391
171 5BVA FAD 2.62391
172 4X9M FAD 2.62391
173 4FWE FAD 2.62391
174 3AB1 FAD 2.62391
175 5WGR FAD 2.62391
176 6ER9 FAD 2.62391
177 6ER9 NAP 2.62391
178 3UCL NAP 2.62391
179 3UCL FAD 2.62391
180 3UCL CYH 2.62391
181 5TUF TDC 2.62391
182 6FHO FAD 2.62391
183 4EIP FAD 2.62391
184 3NKS FAD 2.62391
185 5ICE 2H4 2.62391
186 5ICE SAH 2.62391
187 5J7X FAD 2.62391
188 5NA1 FAD 2.62391
189 5W7R SAH 2.62391
190 5TUF FAD 2.62391
191 5JAQ NAI 2.62391
192 2CDC NAP 2.62391
193 2CDC XYP 2.62391
194 5TUK FAD 2.62391
195 3DAG FEG 2.62391
196 5YSI NCA 2.63158
197 5N6C NAD 2.66667
198 4ZCC FAD 2.67857
199 4ZCC NAI 2.67857
200 2AE2 PTO 2.69231
201 2AE2 NAP 2.69231
202 4EA7 COA 2.72727
203 4EA7 JB2 2.72727
204 1V35 NAI 2.73556
205 3RJ5 NAD 2.75591
206 3FPZ AHZ 2.76074
207 2A92 NAI 2.80374
208 3IHG FAD 2.80374
209 5K4W THR 2.80374
210 5K4W NAI 2.80374
211 3GEG NAD 2.83401
212 1UZN NAP 2.83401
213 1PZM 5GP 2.8436
214 5W7M SAH 2.88462
215 3TKA SAM 2.91545
216 4HA6 FAD 2.91545
217 1RYI GOA 2.91545
218 2GV8 FAD 2.91545
219 1RYI FAD 2.91545
220 2GVC FAD 2.91545
221 1VQW FAD 2.91545
222 6FP4 FAD 2.91545
223 6FP4 E1T 2.91545
224 3GDN FAD 2.91545
225 3GDN HBX 2.91545
226 1U2Z SAH 2.91545
227 2QA1 FAD 2.91545
228 6F7L FAD 2.91545
229 1E6E FAD 2.91545
230 1E1M NAP 2.91545
231 1E1M FAD 2.91545
232 4DMG SAM 2.91545
233 4U8P UDP 2.91545
234 4U8P FDA 2.91545
235 3ZNN FAD 2.91545
236 3ZNN 4WL 2.91545
237 3COB ADP 2.91545
238 4G5H UD7 2.91545
239 4G5H NAP 2.91545
240 5YV5 ADP 2.91545
241 5UR0 NAD 2.91545
242 4I53 1C1 2.91545
243 3HQP FDP 2.91545
244 4JNA FAD 2.94118
245 3T7S SAM 2.98507
246 2Q1W NAD 3.003
247 4JGT PYR 3.01003
248 1XHL NDP 3.0303
249 4E5N NAD 3.0303
250 2A14 SAH 3.04183
251 1UYY BGC BGC 3.05344
252 5Z75 NAD 3.0581
253 5FEU NAP 3.09278
254 1EFV FAD 3.13725
255 1EFV AMP 3.13725
256 5BSZ SAH 3.2
257 3OZG SSI 3.2
258 1GPE FAD 3.207
259 5THY SAH 3.207
260 6F97 FAD 3.207
261 2RGO FAD 3.207
262 4TM3 FAD 3.207
263 1COY FAD 3.207
264 5THZ SAH 3.207
265 5X68 FAD 3.207
266 5TTJ FAD 3.207
267 1COY AND 3.207
268 2VVL FAD 3.207
269 2VVM FAD 3.207
270 2XVE FAD 3.207
271 2RGH FAD 3.207
272 3P9C SAH 3.207
273 3WGT QSC 3.207
274 3WGT FAD 3.207
275 1SAY PYR 3.207
276 5YJS SAL 3.207
277 2VL1 GLY GLY 3.207
278 3MQ2 SAH 3.21101
279 3QJ4 FAD 3.21637
280 3JWH SAH 3.22581
281 4OM8 NAD 3.23625
282 3NUG NAD 3.23887
283 2RH4 EMO 3.2491
284 2PD4 NAD 3.27273
285 2PD4 DCN 3.27273
286 2BD0 NAP 3.27869
287 2JKY 5GP 3.28639
288 3SQP FAD 3.34728
289 3FPF TNA 3.3557
290 3FPF MTA 3.3557
291 1H5Q NAP 3.39623
292 4NEC SAH 3.40909
293 2AG8 NAP 3.42205
294 2BZG SAH 3.44828
295 5OJI ISN 3.46154
296 5OJI NAP 3.46154
297 5FJN FAD 3.49854
298 5FJN BE2 3.49854
299 3QFA FAD 3.49854
300 3CGD FAD 3.49854
301 3CGD COA 3.49854
302 3ICR FAD 3.49854
303 3ICS FAD 3.49854
304 4K5S FAD 3.49854
305 4K5S PM0 3.49854
306 3ICT FAD 3.49854
307 3CGB FAD 3.49854
308 3CGD NAD 3.49854
309 5HXI FAD 3.49854
310 3ICT ADP 3.49854
311 3GWZ SAH 3.49854
312 3GXO SAH 3.49854
313 5HXI 5HN 3.49854
314 4RSL FAD 3.49854
315 3GMB FAD 3.49854
316 3TKY SAH 3.49854
317 1X14 NAD 3.49854
318 5THQ NDP 3.49854
319 2IZ1 ATR 3.49854
320 1YBH FAD 3.49854
321 2IV2 MGD 3.49854
322 2WET FAD 3.49854
323 4EDF UPG 3.49854
324 5O9F 9ON 3.49854
325 5O9F NAD 3.49854
326 2IXB NAD 3.49854
327 2IXB A2G 3.49854
328 1UP7 NAD 3.49854
329 3ICS ADP 3.49854
330 5FFF 5XC 3.50195
331 5FFF NAP 3.50195
332 4UP3 FAD 3.50318
333 5H4S RAM 3.52113
334 3O26 NDP 3.53698
335 2JHP SAH 3.57143
336 3SJ7 NDP 3.57143
337 5EJ2 NAD 3.57143
338 3MAG SAH 3.58306
339 1WMA AB3 3.62319
340 1WMA NDP 3.62319
341 6AA8 NAD 3.64238
342 3MCT SAH 3.7037
343 2O66 FLC 3.7037
344 2PX8 SAH 3.71747
345 3CTY FAD 3.76176
346 2EJU SAH 3.79009
347 4KIB SAH 3.79009
348 1SQF SAM 3.79009
349 1NAA ABL 3.79009
350 1NAA 6FA 3.79009
351 5MBX SP5 3.79009
352 5MBX FAD 3.79009
353 4C3Y FAD 3.79009
354 4C3Y ANB 3.79009
355 1FP1 SAH 3.79009
356 1QZZ SAM 3.79009
357 1GTE FAD 3.79009
358 2FR1 NDP 3.79009
359 2NPX FAD 3.79009
360 2NPX NAD 3.79009
361 6IS0 SAH 3.79009
362 2VL8 CTS 3.79009
363 4E70 N7I 3.79009
364 4J1Q NDP 3.79009
365 4RDH AMP 3.81944
366 4RDI ATP 3.81944
367 6AIN FAD 3.82775
368 1E3W NAD 3.83142
369 3WDM ADN 3.83142
370 1E6W NAD 3.84615
371 3TN7 NJP 3.89105
372 3GCZ SAM 3.90071
373 4Y9D NAI 3.93443
374 5KVA SAM 3.95683
375 3F8D FAD 4.02477
376 1T26 NAI 4.03727
377 1T26 GBD 4.03727
378 5F1V 3VN 4.0404
379 2PK3 A2R 4.04984
380 1NW5 SAM 4.07523
381 1YQZ FAD 4.08163
382 3NYC IAR 4.08163
383 3NYC FAD 4.08163
384 1XHC FAD 4.08163
385 3AXB FAD 4.08163
386 3AXB PRO 4.08163
387 1FEC FAD 4.08163
388 4CNK FAD 4.08163
389 4A6D SAM 4.08163
390 3OJO NAD 4.08163
391 4D5G FAD 4.08163
392 4D5G TPP 4.08163
393 1OBB NAD 4.08163
394 1GQ2 NAP 4.08163
395 6C5B SAH 4.10557
396 3P7G MAN 4.10959
397 1NU4 MLA 4.12371
398 4XUC SAM 4.12844
399 4XUC 43G 4.12844
400 5E1M SAH 4.14938
401 5E1M PRO PRO LYS ARG ILE ALA 4.14938
402 2HMT NAI 4.16667
403 4NTC FAD 4.1791
404 1NFQ NAI 4.23077
405 1XCL SAH 4.25532
406 5FTW SAH 4.29688
407 5L53 NAP 4.32099
408 1XTP SAI 4.33071
409 3LKZ SFG 4.36137
410 5X62 SAH 4.37318
411 3KLJ FAD 4.37318
412 3QOX SAH 4.37318
413 3X0V FAD 4.37318
414 1BZL FAD 4.37318
415 1BZL GCG 4.37318
416 6GAR FAD 4.37318
417 4MIG G3F 4.37318
418 1FUR MLT 4.37318
419 3FG2 FAD 4.37318
420 4HXY NDP 4.37318
421 1XG5 NAP 4.37318
422 5F2K OCA 4.37318
423 5F2K SAH 4.37318
424 4N49 SAM 4.37318
425 4USQ FAD 4.37318
426 1XSE NDP 4.40678
427 4RF2 NAP 4.41176
428 5O98 NAP 4.4164
429 3QWI NAP 4.44444
430 3QWI CUE 4.44444
431 2AG5 NAD 4.47154
432 1ZGA SAH 4.48179
433 5MW4 5JU 4.49102
434 4PLT OXM 4.53172
435 4PLT NAI 4.53172
436 5FUI APY 4.54545
437 2HJR APR 4.57317
438 3DXY SAM 4.58716
439 4YUW S4M 4.60526
440 4YUW 4JU 4.60526
441 5UFN SAH 4.62185
442 3U4C NDP 4.62633
443 1GET FAD 4.66472
444 1GET NAP 4.66472
445 4D7E FAD 4.66472
446 3LAD FAD 4.66472
447 5BJX NAD 4.66472
448 5BJX UDP 4.66472
449 5JWC FAD 4.66472
450 4YT4 FE9 4.66472
451 1MUU NAD 4.66472
452 5LOG SAH 4.72103
453 3ITJ FAD 4.73373
454 3ITJ CIT 4.73373
455 2F7A BEZ 4.74138
456 5Y8L HUI 4.74576
457 5Y8L NAD 4.74576
458 1ZK4 NAP 4.78088
459 1ZK4 AC0 4.78088
460 4JCA CIT 4.79042
461 4Z0H NAD 4.79042
462 2Q0L FAD 4.82315
463 1FL2 FAD 4.83871
464 1N5D NDP 4.86111
465 2Q7V FAD 4.92308
466 4P83 U5P 4.94506
467 5ERG SAM 4.95627
468 3HDY GDU 4.95627
469 3HDY FDA 4.95627
470 3HDY FAD 4.95627
471 2NVK FAD 4.95627
472 4OPC FDA 4.95627
473 4OPC PGT 4.95627
474 5KOK SAH 4.95627
475 5KOK S9T 4.95627
476 5YB7 FAD 4.95627
477 5YB7 ORN 4.95627
478 5KOK R9T 4.95627
479 1DJN ADP 4.95627
480 2PT9 S4M 4.98442
481 2PT9 2MH 4.98442
482 1XKQ NDP 5
483 1P1C SAH 5.02513
484 1KYQ NAD 5.10949
485 4YAG NAI 5.19031
486 3HB5 NAP 5.19878
487 4NBU NAI 5.2
488 1KPH SAH 5.22648
489 1KPG SAH 5.22648
490 3MBI HSX 5.22648
491 3C6K MTA 5.24781
492 2R4J 13P 5.24781
493 2R4J FAD 5.24781
494 1QO8 FAD 5.24781
495 5G3U FDA 5.24781
496 1KNR FAD 5.24781
497 5G3U ITW 5.24781
498 3C6K SPD 5.24781
499 2Z48 NGA 5.24781
500 5ZBC FAD 5.24781
501 1E5Q NDP 5.24781
502 2Z49 AMG 5.24781
503 5JE0 AZ8 5.26316
504 5JE0 SAH 5.26316
505 5JCA FAD 5.28169
506 5JCA NDP 5.28169
507 3OZ2 FAD 5.28967
508 1PR9 NAP 5.32787
509 3D3W NAP 5.32787
510 1GZ6 NAI 5.32915
511 3K7M FAD 5.33643
512 6DUB SAH 5.40541
513 1JQ3 AAT 5.40541
514 4FC7 NAP 5.41516
515 4FC7 COA 5.41516
516 2WPF FAD 5.53936
517 2Z3Y F2N 5.53936
518 3GD4 FAD 5.53936
519 3GD4 NAD 5.53936
520 5OC1 FAD 5.53936
521 2WPF WPF 5.53936
522 1PN0 FAD 5.53936
523 1PN0 IPH 5.53936
524 4BJZ FAD 5.53936
525 4BJZ P3A 5.53936
526 1KYZ SAH 5.53936
527 6H3O FAD 5.53936
528 3LXD FAD 5.53936
529 5NMX FAD 5.53936
530 5NMX NAP 5.53936
531 1Y8Q ATP 5.53936
532 4KGD FAD 5.53936
533 4KGD TDP 5.53936
534 5MB4 NAG 5.53936
535 3NJ4 NAD 5.53936
536 4YJK URA 5.55556
537 1TPY SAH 5.57491
538 1RJW ETF 5.60472
539 1YXM ADE 5.61056
540 2I7C AAT 5.65371
541 3W6X HZP 5.67686
542 2RBK VN4 5.74713
543 1U7T TDT 5.74713
544 1U7T NAD 5.74713
545 3BGD SAH 5.76923
546 3BGD PM6 5.76923
547 1UAY ADN 5.78512
548 1ZBQ NAD 5.8104
549 4RVG TYD 5.8309
550 4RVG SAM 5.8309
551 3PT9 SAH 5.8309
552 4IV9 FAD 5.8309
553 4YAC NAI 5.8309
554 5U8U FAD 5.8309
555 1Q1R FAD 5.8309
556 2JB2 PHE 5.8309
557 2JB2 FAD 5.8309
558 2E5V FAD 5.8309
559 4NBT NAD 5.83333
560 3IWD M2T 5.88235
561 5TVF CGQ 5.88235
562 1O97 FAD 5.9375
563 1O97 AMP 5.9375
564 1O94 ADP 5.9375
565 1FWV SGA MAG FUC 5.97015
566 5BW4 SAM 5.99251
567 4POO SAM 6
568 3FZG SAM 6
569 5TQZ GLC 6
570 4II2 ATP 6.0241
571 2PXX SAH 6.04651
572 2VT3 ATP 6.04651
573 4XZ3 ACP 6.08696
574 5J5Z FAD 6.12245
575 4B63 ORN 6.12245
576 4B63 NAP 6.12245
577 4B63 FAD 6.12245
578 2F5Z FAD 6.12245
579 3LST SAH 6.12245
580 1I8T FAD 6.12245
581 2C7G ODP 6.12245
582 2C7G FAD 6.12245
583 4UCI SAM 6.12245
584 1U1I NAD 6.12245
585 6F3M NAD 6.12245
586 1UXG FUM 6.14887
587 1UXG NAD 6.14887
588 4PIO AVI 6.19195
589 4PIO SAH 6.19195
590 3A28 NAD 6.20155
591 1JA9 NDP 6.20438
592 4OBW SAM 6.22568
593 6GNA FAD 6.25
594 1LDN NAD 6.32911
595 2VHW NAI 6.36605
596 1MZV AMP 6.38298
597 4DCM SAM 6.41399
598 5F8F SFG 6.41399
599 4J36 1HR 6.41399
600 4J36 FAD 6.41399
601 5XNC MTA 6.41399
602 2V6G NAP 6.41399
603 5MLR NAP 6.41399
604 5MLR GRQ 6.41399
605 3WV8 ATP 6.42202
606 2DTX BMA 6.43939
607 1ICV NIO 6.45161
608 3WLE NAD 6.45161
609 2BGM NAJ 6.47482
610 2VDV SAM 6.50407
611 1DQN IMU 6.52174
612 3O03 NAP 6.52921
613 4P86 5GP 6.55738
614 2FJK 13P 6.55738
615 2OBF SAH 6.57439
616 2OBF F83 6.57439
617 5GSN FAD 6.62252
618 5GSN NAP 6.62252
619 5GSN MMZ 6.62252
620 3A4V NAD 6.62461
621 3A4V PYR 6.62461
622 1TDF NAP 6.64557
623 1TDF FAD 6.64557
624 1NNU TCT 6.66667
625 1NNU NAD 6.66667
626 5MZI FYK 6.70554
627 5MZI FAD 6.70554
628 5Y77 FAD 6.70554
629 2YVF FAD 6.70554
630 2YVF NAD 6.70554
631 5G48 1FL 6.70554
632 4HDK 13X 6.70554
633 5XLX SAH 6.70554
634 5M67 NAD 6.70554
635 2ZIF SAM 6.73401
636 3ZV6 4HB 6.76157
637 3ZV6 NAD 6.76157
638 5JE8 NAD 6.95364
639 3AFN NAP 6.97674
640 4REP FAD 6.99708
641 4LHD GLY 6.99708
642 1O0S NAI 6.99708
643 3GFB NAD 6.99708
644 2OFD NGA 7.04225
645 5I39 FAD 7.10784
646 2Q46 NAP 7.11462
647 4TQG NDP 7.12074
648 2Q1S NAI 7.1618
649 1O5O U5P 7.23982
650 2WA2 SAM 7.24638
651 6ECU SAH 7.27848
652 1REO FAD 7.28863
653 4YRY FAD 7.28863
654 4YRY NAD 7.28863
655 4EMI NAD 7.28863
656 4EMI FAD 7.28863
657 1GZ4 ATP 7.28863
658 1X7D NAD 7.28863
659 1X7D ORN 7.28863
660 6ECW SAH 7.30159
661 1G60 SAM 7.30769
662 5U19 SAH 7.33138
663 5U19 827 7.33138
664 1Q0S SAH 7.33591
665 2YY7 NAD 7.37179
666 1QAN SAH 7.37705
667 1RP0 AHZ 7.39437
668 5CIC 51R 7.40741
669 4AZW SAM 7.431
670 5AHO TLA 7.44048
671 2ZFU SAH 7.44186
672 2IID PHE 7.58017
673 2IID FAD 7.58017
674 3RNM FAD 7.58017
675 4TQK NAG 7.58017
676 2DFV NAD 7.58017
677 2HXW FLC 7.59494
678 2ZQO NGA 7.69231
679 3ACC 5GP 7.73481
680 2FKA BEF 7.75194
681 1R37 NAD 7.78098
682 3VYW SAM 7.79221
683 6GAS FAD 7.85498
684 5MPT SAH 7.87172
685 1MO9 KPC 7.87172
686 1MO9 FAD 7.87172
687 5HJM MTA 7.87172
688 4EUE NAI 7.87172
689 1K3T BRZ 7.87172
690 4J56 FAD 7.89474
691 1L1E SAH 8.01394
692 5GWX SAR 8.09859
693 5GWX SAM 8.09859
694 4TXI FAD 8.16327
695 2BRY FAD 8.16327
696 5HSA FAS 8.16327
697 4MOP 2H5 8.16327
698 5ZYN FAD 8.16327
699 1SB8 UD2 8.23864
700 1SB8 NAD 8.23864
701 2YVJ FAD 8.25688
702 2YVJ NAI 8.25688
703 1W8D NAP 8.27815
704 1W73 NAP 8.27815
705 4EMJ FAD 8.41121
706 3LZW NAP 8.43373
707 3LZW FAD 8.43373
708 4MO2 FDA 8.45481
709 4MO2 FAD 8.45481
710 5M90 JIF 8.45481
711 6AR9 3L4 8.45588
712 2DT5 NAD 8.53081
713 4FN4 NAD 8.66142
714 4M52 FAD 8.74636
715 2A8X FAD 8.74636
716 4M52 M52 8.74636
717 3RKR NAP 8.74636
718 2CFC NAD 8.8
719 1QG6 NAD 8.81226
720 1QG6 TCL 8.81226
721 2P41 SAH 8.85246
722 3P2E SAH 8.88889
723 1W6U NAP 8.9404
724 1I7M CG 8.95522
725 5E9W SAH 8.97436
726 5GWT SIN 8.99281
727 5GWT NAD 8.99281
728 3BF8 MLA 9.01961
729 1NHK CMP 9.02778
730 5T67 SAH 9.0379
731 5T67 JHZ 9.0379
732 6GKV SAH 9.0379
733 4D79 ATP 9.05797
734 2GAG NAD 9.09091
735 2GAG FAD 9.09091
736 2GAG FOA 9.09091
737 2ZAT NAP 9.23077
738 1HGX 5GP 9.28962
739 5N5D SAM 9.29204
740 4KRG SAH 9.32945
741 2HQM FAD 9.32945
742 2BVL UDP 9.32945
743 2BVL GLC 9.32945
744 5DF1 58X 9.32945
745 5DF1 NAP 9.32945
746 4CQM NAP 9.42623
747 2YX1 SFG 9.52381
748 1ZEM NAD 9.54198
749 4YSX FAD 9.61539
750 1I9G SAM 9.64286
751 5T2U NAP 9.67742
752 2JBH 5GP 9.77778
753 3QDV A2G 9.79021
754 3QDW A2G 9.79021
755 3QDX A2G GAL 9.79021
756 3QDT A2G GAL 9.79021
757 3EVG SAH 9.81818
758 2O07 SPD 9.86842
759 2O07 MTA 9.86842
760 3PFG TLO 9.88593
761 3PFG SAM 9.88593
762 1AE1 NAP 9.89011
763 6C8R SAH 9.91254
764 6C8R EQV 9.91254
765 6B3A SAM 9.91254
766 3A27 SAM 9.92647
767 6F9Q NAD 9.92647
768 6F5Z SAH 9.95671
769 2PWY SAH 10.0775
770 5ZZ6 ADP 10.0962
771 5ZZ6 NAD 10.0962
772 3EVF SAH 10.1083
773 3EVF GTA 10.1083
774 4PLG OXM 10.1796
775 4PLG NAI 10.1796
776 3S1S SAH 10.2041
777 4NTD FAD 10.2041
778 5O42 BGC 10.2041
779 5O42 9JW 10.2041
780 5O42 NAD 10.2041
781 4URF NAD 10.4839
782 1IY8 NAD 10.4869
783 3T31 DCQ 10.4956
784 3T31 FAD 10.4956
785 2AQJ TRP 10.4956
786 2AQJ FAD 10.4956
787 6DEN TP9 10.4956
788 6DEN FAD 10.4956
789 6DEN G8A 10.4956
790 2XVM SAH 10.5528
791 1G0N NDP 10.6007
792 1G0N PHH 10.6007
793 3A25 SAM 10.6312
794 1DL5 SAH 10.7256
795 3VSE SAH 10.7872
796 5WP4 SAH 10.7872
797 3NTD FAD 10.7872
798 3NT6 FAD 10.7872
799 3NTA FAD 10.7872
800 3LN9 FLC 10.7914
801 3BXO SAM 10.8787
802 3VZS NAP 10.8949
803 3VZS CAA 10.8949
804 4KRI SAH 11.0787
805 5KMS NAD 11.0787
806 4XQC 13D 11.0787
807 4XQC NAD 11.0787
808 5KMS FAD 11.0787
809 1GEG NAD 11.3281
810 1Z3C SA8 11.4094
811 5MGZ SAH 11.4407
812 2B4Q NAP 11.6618
813 2Q28 ADP 11.6618
814 3AD8 PYC 11.8227
815 3AD8 FAD 11.8227
816 3AD8 NAD 11.8227
817 6B92 SAH 11.9048
818 1L7N ALF 12.3223
819 5YJI 8WO 12.3239
820 5YJI SAH 12.3239
821 1V59 NAD 12.3431
822 1V59 FAD 12.3431
823 5J60 FAD 12.5
824 4QED NAP 12.5
825 3E1T FAD 12.5364
826 4L2I FAD 12.5364
827 5L4S 6KX 12.5364
828 5L4S NAP 12.5364
829 5YJF SAH 12.6761
830 5YJF 8WO 12.6761
831 3Q87 SAM 12.8
832 3H2B SAH 12.8079
833 5JJR SAH 12.828
834 3MB5 SAM 12.9412
835 5GM1 SAH 13.1313
836 3LCV SAM 13.1673
837 6BQ6 TER 13.2931
838 2AOT SAH 13.3562
839 1JQD HSM 13.3562
840 1JQD SAH 13.3562
841 5ODQ FAD 13.3779
842 1QK3 5GP 13.7339
843 6GFK SAH 13.9442
844 6FX2 FUC C4W NAG BMA MAN NAG GAL 13.9535
845 1QB7 ADE 13.9831
846 1NVM NAD 13.9942
847 4NBW NAD 14.0078
848 5ULP KB1 14.1791
849 3OU2 SAH 14.2202
850 4PNE SAH 14.2384
851 1JNR FAD 15.3333
852 4J4H NAI 15.444
853 4J4H 1J1 15.444
854 1LSS NAD 15.7143
855 3G2O SAM 15.7191
856 5E8J SAH 15.9091
857 1I1N SAH 15.9292
858 5VJN IR8 16.0428
859 1WKL ATP 16.0584
860 3ELW SAM 16.3333
861 3ELW GP3 16.3333
862 5CUQ NSC 16.4794
863 1JG3 ADN 16.5957
864 6GNC FAD 16.6667
865 5FA8 SAM 16.7702
866 1OAA OAA 16.9884
867 6CI9 NAP 17.7606
868 2PS1 ORO 18.1416
869 4R6W PC 18.6047
870 4R6W SAH 18.6047
871 4GUT FAD 19.3548
872 4GUS FAD 19.3548
873 4HSU FAD 19.3548
874 1BW9 NAD 20.1166
875 2HNK SAH 23.0126
876 1VE3 SAM 23.348
877 5YEC ATP 23.5294
878 4LWP SAH 25.656
879 3HVJ 705 25.7919
880 4JLS 3ZE 26.3158
881 1L3I SAH 26.5625
882 1R18 SAH 29.5154
883 4KWI 1TJ 30.4183
884 4KWI NAP 30.4183
885 5FUB SAH 35.0148
886 6ARJ BW4 35.5685
887 5DWQ SFG 35.5685
888 5DX1 SFG 35.5685
889 5DXA SFG 35.5685
890 5DX8 SFG 35.5685
891 5DX0 SFG 35.5685
892 6ARJ SAH 35.5685
893 4GQB 0XU 36.3636
894 5FWA J7C 36.7347
895 5FA5 MTA 40
896 1F3L SAH 42.3676
Pocket No.: 2; Query (leader) PDB : 4M37; Ligand: SAH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4m37.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
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