Receptor
PDB id Resolution Class Description Source Keywords
4M9Q 2.5 Å EC: 3.6.5.2 CRYSTAL STRUCTURE OF C-TERMINALLY TRUNCATED ARL13B FROM CHLA RHEINHARDTII BOUND TO GPPNHP CHLAMYDOMONAS REINHARDTII GTPASE G DOMAIN JOUBERT SYNDROME CILIA HYDROLASE
Ref.: STRUCTURAL INSIGHTS INTO THE SMALL G-PROTEIN ARL13B IMPLICATIONS FOR JOUBERT SYNDROME. BIOCHEM.J. V. 457 301 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SO4 C:303;
B:303;
A:303;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
MG C:302;
A:302;
B:302;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
GNP B:301;
A:301;
C:301;
Valid;
Valid;
Valid;
none;
none;
none;
submit data
522.196 C10 H17 N6 O13 P3 c1nc2...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4M9Q 2.5 Å EC: 3.6.5.2 CRYSTAL STRUCTURE OF C-TERMINALLY TRUNCATED ARL13B FROM CHLA RHEINHARDTII BOUND TO GPPNHP CHLAMYDOMONAS REINHARDTII GTPASE G DOMAIN JOUBERT SYNDROME CILIA HYDROLASE
Ref.: STRUCTURAL INSIGHTS INTO THE SMALL G-PROTEIN ARL13B IMPLICATIONS FOR JOUBERT SYNDROME. BIOCHEM.J. V. 457 301 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 17 families.
1 4M9Q - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 14 families.
1 4M9Q - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 10 families.
1 4M9Q - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GNP; Similar ligands found: 128
No: Ligand ECFP6 Tc MDL keys Tc
1 GNP 1 1
2 GDP 0.839506 0.973684
3 GP3 0.82716 0.948718
4 GTP 0.809524 0.973684
5 GNH 0.807229 0.986842
6 G1R 0.77907 0.961039
7 GCP 0.77907 0.948718
8 GSP 0.770115 0.925
9 5GP 0.756098 0.960526
10 G 0.756098 0.960526
11 G2R 0.747253 0.936709
12 GMV 0.747126 0.948718
13 GAV 0.714286 0.936709
14 GP2 0.712644 0.936709
15 G2P 0.711111 0.936709
16 Y9Z 0.708333 0.880952
17 GDP MG 0.696629 0.9
18 GDD 0.690722 0.936709
19 GDC 0.690722 0.936709
20 GKE 0.690722 0.936709
21 GDP BEF 0.688889 0.878049
22 G5P 0.686869 0.948718
23 GPG 0.684211 0.936709
24 GTG 0.683673 0.91358
25 GFB 0.683673 0.936709
26 GDR 0.683673 0.936709
27 JB2 0.68 0.936709
28 GKD 0.68 0.936709
29 G3A 0.676768 0.948718
30 6CK 0.676768 0.91358
31 GDX 0.673267 0.948718
32 ALF 5GP 0.67033 0.86747
33 GTP MG 0.666667 0.9
34 BEF GDP 0.666667 0.86747
35 YGP 0.663265 0.879518
36 GCP G 0.659574 0.911392
37 GPD 0.656863 0.902439
38 GDP AF3 0.645833 0.86747
39 GDP ALF 0.645833 0.86747
40 JB3 0.641509 0.925
41 DBG 0.640351 0.974359
42 G3D 0.638298 0.960526
43 G4P 0.625 0.960526
44 GMP 0.621951 0.857143
45 NGD 0.62037 0.936709
46 GGM 0.618182 0.925926
47 0O2 0.616162 0.960526
48 G G 0.61 0.911392
49 2MD 0.603604 0.870588
50 CAG 0.60177 0.904762
51 U2G 0.590909 0.91358
52 FEG 0.590909 0.858824
53 GDP 7MG 0.590476 0.888889
54 MGD 0.587719 0.870588
55 ZGP 0.585586 0.848837
56 CG2 0.580357 0.91358
57 ANP 0.568421 0.922078
58 PGD 0.567797 0.902439
59 MD1 0.567797 0.870588
60 3GP 0.56044 0.922078
61 TPG 0.558333 0.822222
62 GH3 0.55 0.948052
63 FE9 0.546219 0.778947
64 GPX 0.539216 0.922078
65 G4M 0.539062 0.860465
66 DGI 0.536082 0.9
67 BGO 0.535088 0.901235
68 IDP 0.53125 0.947368
69 DGT 0.53 0.9
70 2GP 0.526882 0.935065
71 G1R G1R 0.520325 0.901235
72 I2C FE2 CMO CMO 0.516667 0.811111
73 U A G G 0.512605 0.911392
74 AGO 0.504202 0.91358
75 G A A A 0.504202 0.9
76 P2G 0.5 0.860759
77 G1G 0.5 0.902439
78 MGP 0.49505 0.936709
79 PGD O 0.492063 0.831461
80 6G0 0.490196 0.936709
81 P1G 0.489796 0.85
82 DGP 0.474227 0.8875
83 DG 0.474227 0.8875
84 G G U 0.473684 0.911392
85 IMP 0.463918 0.934211
86 G2Q 0.462963 0.936709
87 GPC 0.459677 0.858824
88 G C 0.459016 0.878049
89 GTA 0.448276 0.91358
90 G7M 0.444444 0.924051
91 MAP 0.439252 0.898734
92 G G G RPC 0.435484 0.853659
93 B4P 0.434343 0.871795
94 AP5 0.434343 0.871795
95 ADP 0.434343 0.896104
96 A2D 0.43299 0.871795
97 U G A 0.431655 0.86747
98 G G G C 0.426357 0.890244
99 SGP 0.425743 0.807229
100 AU1 0.425743 0.922078
101 BA3 0.424242 0.871795
102 35G 0.423077 0.909091
103 PCG 0.423077 0.909091
104 A G C C 0.423077 0.888889
105 C2E 0.423077 0.897436
106 APC G U 0.421875 0.864198
107 ATP 0.421569 0.896104
108 ACQ 0.419048 0.873418
109 5GP 5GP 0.419048 0.860759
110 AQP 0.417476 0.896104
111 5FA 0.417476 0.896104
112 01G 0.417391 0.880952
113 UNP 0.415842 0.810127
114 AN2 0.415842 0.909091
115 6AD 0.415094 0.821429
116 ITT 0.411765 0.846154
117 M33 0.411765 0.860759
118 G C C C 0.410448 0.901235
119 G U34 0.408 0.86747
120 ACP 0.407767 0.873418
121 APR 0.403846 0.871795
122 AR6 0.403846 0.871795
123 DG DG 0.403509 0.845238
124 A4P 0.403226 0.848837
125 UCG 0.402985 0.888889
126 AD9 0.4 0.873418
127 SAP 0.4 0.851852
128 AGS 0.4 0.851852
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4M9Q; Ligand: GNP; Similar sites found: 524
This union binding pocket(no: 1) in the query (biounit: 4m9q.bio1) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4DKX GDP 0.00000000002666 0.83308 None
2 1YZQ GNP 0.000000000001229 0.81946 None
3 2Y8E GNP 0.000000000002534 0.73465 None
4 1GXU 2HP 0.0009743 0.4724 None
5 3GUZ PAF 0.02891 0.40081 1.70455
6 1G6O ADP 0.0001681 0.48994 1.76211
7 3BFV ADP 0.000007164 0.4635 1.76211
8 4NE2 SH2 0.001734 0.44221 1.76211
9 4NE2 ADP 0.001522 0.44221 1.76211
10 4BFW ZVW 0.002997 0.43506 1.76211
11 1CR1 TTP 0.001304 0.42244 1.76211
12 4JLV ADP 0.0001639 0.41034 1.76211
13 1D2E GDP 0.0000000008726 0.6361 2.20264
14 4IEE AGS 0.000688 0.47796 2.20264
15 5GJC ATP 0.00007133 0.42852 2.20264
16 4GOX A3P 0.001942 0.42247 2.20264
17 1D2N ANP 0.002913 0.40838 2.20264
18 2CHG ANP 0.001295 0.41202 2.21239
19 1O8B ABF 0.02359 0.40104 2.28311
20 4IDN GNP 0.0000254 0.49914 2.407
21 1G3Q ADP 0.0000636 0.44095 2.53165
22 5GOE GDP 0.000000000723 0.6261 2.64317
23 2NCD ADP 0.00001993 0.56927 2.64317
24 1IWE IMP 0.0001598 0.5329 2.64317
25 3FWY ADP 0.00005079 0.46632 2.64317
26 3QXC ATP 0.000489 0.4531 2.64317
27 1BG2 ADP 0.0000009182 0.43046 2.64317
28 3EWA ANP 0.00008329 0.42362 2.64317
29 3BER AMP 0.006829 0.42354 2.64317
30 4FCW ADP 0.00108 0.40358 2.64317
31 3BFX A3P 0.003404 0.40121 2.64317
32 2QQ0 TMP 0.001534 0.43939 2.71739
33 2QQ0 ANP 0.001659 0.43791 2.71739
34 2QQ0 THM 0.001607 0.43569 2.71739
35 4M7V RAR 0.008945 0.41853 2.85714
36 4M7V NAP 0.006978 0.41067 2.85714
37 2C78 GNP 0.0000000000008034 0.81172 3.0837
38 2C77 GNP 0.0000000000003584 0.81102 3.0837
39 3E70 GDP 0.000001069 0.50412 3.0837
40 4Q1A 2XZ 0.003075 0.484 3.0837
41 4Q1A UDP 0.003075 0.484 3.0837
42 3EZ2 ADP 0.0006733 0.47843 3.0837
43 1XKV ATP 0.00008073 0.44437 3.0837
44 1NJF AGS 0.0006259 0.44113 3.0837
45 1OS1 PYR 0.001386 0.43846 3.0837
46 1NJF ADP 0.0004191 0.43649 3.0837
47 1OS1 ATP 0.001658 0.43362 3.0837
48 3FYH ADP 0.002144 0.42242 3.0837
49 1T5C ADP 0.000003869 0.41537 3.0837
50 2XAU ADP 0.0004753 0.41407 3.0837
51 3FIU POP 0.02711 0.40327 3.0837
52 1DAK DPU 0.0002555 0.48532 3.125
53 1DAK ADP 0.006725 0.4492 3.125
54 2J0V GDP 0.00000001768 0.56709 3.30189
55 3KTA AP5 0.0004232 0.4239 3.46821
56 1XEX ATP 0.001649 0.40454 3.48837
57 2FFQ GSP 0.000000000001509 0.81567 3.52423
58 4RD0 GDP 0.00000000000205 0.79477 3.52423
59 3WYA GDP 0.00000000001803 0.64783 3.52423
60 2ZFI ADP 0.00001179 0.55815 3.52423
61 4PFO ADP 0.00007573 0.48567 3.52423
62 1UJ2 C5P 0.000613 0.44892 3.52423
63 1UJ2 ADP 0.0009751 0.44033 3.52423
64 1P72 ADP 0.001486 0.43999 3.52423
65 1ION ADP 0.0001469 0.4356 3.52423
66 4FRZ ADP 0.00001759 0.42024 3.52423
67 1G41 ADP 0.0005327 0.41568 3.52423
68 2GDJ ANP 0.0002487 0.41249 3.52423
69 1NHX PEP 0.01275 0.40971 3.52423
70 1NHX FTB 0.01351 0.40946 3.52423
71 2GMV UN8 0.006876 0.40559 3.52423
72 2GMV PEP 0.01044 0.4005 3.52423
73 1I4D GDP 0.00000002324 0.54106 3.64583
74 1G4U GDP 0.0000009374 0.54272 3.80435
75 2FJU GSP 0.0000000007847 0.67703 3.93258
76 2W58 ADP 0.000004763 0.40779 3.9604
77 2C04 GCP 0.000008029 0.53781 3.96476
78 4LPS GDP 0.0000001391 0.5341 3.96476
79 2WOJ ADP ALF 0.00005 0.49529 3.96476
80 5J1J ANP 0.0001004 0.47642 3.96476
81 4XTR ATP 0.0001339 0.47118 3.96476
82 4XVU ATP 0.0001456 0.46965 3.96476
83 4XGU ADP 0.00006397 0.46247 3.96476
84 3KJI ADP 0.00005559 0.46049 3.96476
85 4XTR ADP 0.0001971 0.44981 3.96476
86 1YTM ATP 0.0005343 0.4481 3.96476
87 4IOK ADP 0.0007971 0.44571 3.96476
88 4IOK XPO 0.0006013 0.44571 3.96476
89 2ZTS ADP 0.001305 0.43554 3.96476
90 3COB ADP 0.000002882 0.4319 3.96476
91 3P4X ADP 0.000049 0.42752 3.96476
92 3BOS CDP 0.0001123 0.42103 3.96476
93 4YS0 ADP 0.001937 0.40591 3.96476
94 3UIE ANP 0.00003733 0.45346 4
95 2A9K GDP 0.000000007045 0.6149 4.03587
96 1U8Z GDP 0.000000003159 0.64696 4.16667
97 3H86 AP5 0.0005657 0.4611 4.16667
98 5JCP GDP ALF 0.000000003073 0.68947 4.40529
99 1GOJ ADP 0.0000005652 0.664 4.40529
100 4H1V GNP 0.0000009343 0.57927 4.40529
101 5L3V GDP 0.0000006577 0.52127 4.40529
102 4R43 GDP 0.0002373 0.49466 4.40529
103 1KK8 BEF ADP 0.0000193 0.48092 4.40529
104 5N69 ADP 0.00004534 0.45838 4.40529
105 3IO3 ADP 0.0001736 0.45197 4.40529
106 1B7T ADP 0.0001209 0.43765 4.40529
107 1IN4 ADP 0.0009197 0.42295 4.40529
108 2FAH GDP 0.0007181 0.41886 4.40529
109 1T8U UAP SGN IDS SGN 0.01029 0.41103 4.40529
110 5XDR ADP 0.0003745 0.41092 4.40529
111 5DRB 5FJ 0.01339 0.41053 4.40529
112 4IHQ ADP 0.0001944 0.40385 4.40529
113 1UKZ ADP 0.002141 0.43441 4.4335
114 3IIJ ADP 0.00001647 0.44858 4.44444
115 5G41 AP5 0.002558 0.44328 4.4843
116 1ZIN AP5 0.001167 0.45339 4.60829
117 4MKG AP5 0.001306 0.45121 4.60829
118 4MKF AP5 0.001567 0.44877 4.60829
119 1W4R TTP 0.00318 0.41997 4.61538
120 3FB4 AP5 0.0008902 0.45866 4.62963
121 1YRB GDP 0.000000001051 0.63533 4.84582
122 1G7C 5GP 0.0000000059 0.57212 4.84582
123 3ZQ6 ADP ALF 0.00003205 0.50352 4.84582
124 1P9B GDP 0.00002071 0.48359 4.84582
125 5VGR GDP 0.0005232 0.4573 4.84582
126 1Z6T ADP 0.000611 0.45431 4.84582
127 3TMK T5A 0.0008947 0.44515 4.84582
128 3RLF ANP 0.000643 0.44261 4.84582
129 1SVM ATP 0.002993 0.44206 4.84582
130 3FVQ ATP 0.0006039 0.43582 4.84582
131 4LYA ATP 0.0001197 0.43192 4.84582
132 1OXV ANP 0.00002424 0.42928 4.84582
133 1G8S MET 0.01756 0.41433 4.84582
134 2AWN ADP 0.0000005346 0.41359 4.84582
135 1JJV ATP 0.00003023 0.41969 4.85437
136 1D5C GDP 0.00000000267 0.63109 4.93827
137 2GCO GNP 0.000000001843 0.63974 4.97512
138 2GCN GDP 0.00000003598 0.61787 4.97512
139 5JBQ GDP 0.00000000001448 0.65077 5.07614
140 4G5G GDP 0.00000000001799 0.64818 5.07614
141 3U6B GDP 0.000000000005628 0.64678 5.07614
142 3U6K GDP 0.0000000001118 0.62695 5.07614
143 2BVN GNP 0.000000000002632 0.83858 5.08906
144 1D8T GDP 0.00000000001728 0.64881 5.08906
145 1NN5 ANP 0.000356 0.46554 5.11628
146 2XTN GTP 0.000004379 0.53345 5.12821
147 1OW3 GDP 0.0000001121 0.57045 5.18135
148 3H4S ADP 0.000005767 0.42175 5.18518
149 4CVN ADP 0.00001948 0.42945 5.2356
150 3B9Q MLI 0.00000264 0.61458 5.28634
151 5L3R GCP 0.0000007451 0.56827 5.28634
152 5I0H ADP BEF 0.0000006455 0.55691 5.28634
153 1JWY GDP 0.0000002783 0.54571 5.28634
154 5I34 GDP 0.000004948 0.48446 5.28634
155 2FNA ADP 0.0001971 0.46206 5.28634
156 2QEN ADP 0.00007031 0.45987 5.28634
157 3Q9L ATP 0.0001169 0.45297 5.28634
158 1JWY ADP 0.00003008 0.44922 5.28634
159 1FNN ADP 0.0007976 0.44483 5.28634
160 1XMV ADP 0.0000587 0.43773 5.28634
161 5TSH ANP 0.00004233 0.43572 5.28634
162 3R7F CP 0.01654 0.41585 5.28634
163 5TSH ADP 0.00009987 0.40158 5.28634
164 1GWN GTP 0.0000000007559 0.67789 5.36585
165 3LXR GDP 0.0000000616 0.64944 5.40541
166 5HPY GDP 0.00000008465 0.57618 5.40541
167 1KMQ GNP 0.0000000003678 0.70432 5.43478
168 4P3Y GDP 0.000000000005022 0.64817 5.49451
169 4XOI GTP 0.0000000005213 0.70128 5.55556
170 1Z0F GDP 0.0000000003921 0.62068 5.58659
171 5H56 ADP 0.0004299 0.46045 5.64103
172 5H56 TYD 0.0004299 0.46045 5.64103
173 1TX4 ALF GDP 0.000000001184 0.66544 5.64972
174 1QF9 C5P 0.006044 0.41817 5.6701
175 1QF9 ALF 0.006044 0.41817 5.6701
176 1QF9 ADP 0.006044 0.41817 5.6701
177 4ZKD GDP 0.000000000002268 0.80813 5.72687
178 4OHY ANP 0.00004757 0.47069 5.72687
179 5IRN ADP 0.0001468 0.44031 5.72687
180 2ZR9 DTP 0.00002693 0.44014 5.72687
181 4O48 ASP 0.0106 0.42587 5.72687
182 4PPF FLC 0.0000002883 0.42376 5.72687
183 1XP8 AGS 0.00006301 0.42336 5.72687
184 3NHB ADP 0.000009475 0.42317 5.72687
185 5LTJ ADP 0.0001916 0.4198 5.72687
186 4U00 ADP 0.00000222 0.41448 5.72687
187 4D81 ADP 0.0007663 0.41414 5.72687
188 5LB3 ADP 0.000262 0.40578 5.72687
189 5TIV A3P 0.0185 0.40235 5.72687
190 1ZUI SKM 0.0001556 0.48717 5.95238
191 1VHT BA3 0.0004131 0.42138 5.9633
192 1M7B GTP 0.000000001122 0.68963 5.97826
193 4TMK T5A 0.009048 0.40695 6.10329
194 3TK1 GDP 0.00000000004219 0.60276 6.1674
195 1E2K TMC 0.001341 0.45069 6.1674
196 2JLR ANP 0.0002283 0.43294 6.1674
197 3CV2 OXL 0.02438 0.40964 6.1674
198 3DZD ADP 0.001377 0.40799 6.1674
199 2ZE7 DST 0.007809 0.40177 6.1674
200 2ZE7 AMP 0.007519 0.40097 6.1674
201 4U5X GNP 0.0000000008445 0.66341 6.17978
202 4QM7 GTP 0.00004852 0.43009 6.43275
203 2W2X GSP 0.0000000005999 0.6814 6.45161
204 2QN6 GDP 0.00000000000683 0.64428 6.45161
205 2ZEJ GDP 0.0000001297 0.60546 6.52174
206 1MKY GDP 0.00000000001287 0.65165 6.60793
207 4PC3 GDP 0.000000002622 0.62016 6.60793
208 2RCN GDP 0.0000000001819 0.61472 6.60793
209 3MD0 GDP 0.00000000004833 0.61435 6.60793
210 4AG5 ADP 0.00000526 0.60069 6.60793
211 4ZG4 VO4 ADP 0.000001739 0.55027 6.60793
212 1F5N GNP 0.000003168 0.49919 6.60793
213 1H65 GDP 0.00006349 0.48256 6.60793
214 3A4M ADP 0.000001984 0.45348 6.60793
215 2RGX AP5 0.00213 0.44386 6.60793
216 4P32 ADP 0.001023 0.43224 6.60793
217 2VF7 ADP 0.0003486 0.41247 6.60793
218 4HSE ADP 0.0003587 0.41076 6.60793
219 4PX9 ADP 0.000322 0.40201 6.60793
220 3B7G ANP 0.0008237 0.40113 6.60793
221 2HF9 GSP 0.0000001779 0.61124 6.63717
222 1Z0A GDP 0.0000000007481 0.62472 6.89655
223 1HTW ADP 0.00003223 0.45073 6.96203
224 2A5J GDP 0.000000001183 0.72911 7.04846
225 1PUJ GNP 0.0000000002757 0.65603 7.04846
226 5FG3 GDP 0.000000000006743 0.64487 7.04846
227 4DCT GDP 0.000000000535 0.61947 7.04846
228 4NON GDP 0.000000073 0.54924 7.04846
229 2B8W ALF 5GP 0.000004334 0.53603 7.04846
230 3T34 GDP 0.000002057 0.5344 7.04846
231 1QF5 GDP 0.00005943 0.52203 7.04846
232 2DPY ADP 0.0004976 0.4914 7.04846
233 1V8K ANP 0.000003055 0.47804 7.04846
234 1QF5 RPL 0.002418 0.47775 7.04846
235 3FKQ ATP 0.0002993 0.46807 7.04846
236 2BIF ANP 0.0006159 0.4581 7.04846
237 2BIF SIN 0.001087 0.4581 7.04846
238 5K5Z ANP 0.0004624 0.45053 7.04846
239 2PZE ATP 0.000003536 0.42185 7.04846
240 1G6H ADP 0.000001297 0.41968 7.04846
241 4WZ6 ATP 0.00001985 0.41594 7.04846
242 1R0X ATP 0.0003731 0.4066 7.04846
243 4KFU ACP 0.000003717 0.44148 7.07547
244 1KO8 6PG 0.0005326 0.43148 7.42857
245 1G7S GDP 0.00000000005037 0.80579 7.48899
246 4LC1 GDP 0.0000000009194 0.7582 7.48899
247 3CNL GNP 0.0000000001241 0.60649 7.48899
248 3DC4 ADP 0.000004436 0.45081 7.48899
249 1K6M AGS 0.001249 0.43051 7.48899
250 2XT3 ADP 0.000003264 0.42933 7.48899
251 1JJ7 ADP 0.000001027 0.42209 7.48899
252 3B5J 12D 0.00005372 0.41305 7.48899
253 4HI0 GDP 0.0000004372 0.57943 7.53769
254 2QG6 NMN 0.001935 0.42921 7.53769
255 4QRH 0O2 0.004141 0.4014 7.61905
256 4ZNL BEF ADP 0.0001252 0.42914 7.66423
257 1S3G AP5 0.0008507 0.45954 7.8341
258 4TTQ ATP 0.00007575 0.43264 7.90698
259 2WIC GNP 0.0000000006201 0.75398 7.92952
260 5HCN GCP 0.000000003933 0.59437 7.92952
261 1JI0 ATP 0.000009845 0.57877 7.92952
262 4WZA ADP 0.00004582 0.53627 7.92952
263 4WZA ACP 0.00004582 0.53627 7.92952
264 4V03 ADP 0.00007575 0.44422 7.92952
265 1FP6 ADP 0.0001645 0.4394 7.92952
266 1SQ5 ADP 0.0001027 0.43011 7.92952
267 2OZE AGS 0.0008087 0.42603 7.92952
268 1NY5 ADP 0.002501 0.40158 7.92952
269 1Y63 ADP 0.000005987 0.46202 8.15217
270 4XSH GSP 0.000000003621 0.63981 8.21918
271 2WKQ GTP 0.000000002273 0.65379 8.37004
272 2CBZ ATP 0.000005059 0.6135 8.37004
273 4R98 GNH 0.0000000336 0.5535 8.37004
274 5FTB ANP 0.0002552 0.48152 8.37004
275 5X40 ACP 0.0003966 0.45141 8.37004
276 5FHD ADP ALF 0.0006187 0.44539 8.37004
277 1B0U ATP 0.000681 0.41266 8.39695
278 2WJG GDP 0.0000000005224 0.77016 8.51064
279 1L2T ATP 0.001007 0.43628 8.51064
280 1W7J ADP BEF 0.00002053 0.51972 8.60927
281 5MVR ADP 0.00003565 0.44258 8.64198
282 2VB6 ADP BEF 0.00005808 0.48639 8.72483
283 1DAR GDP 0.00000000003941 0.63856 8.81057
284 2ZPA ADP 0.0004825 0.43352 8.81057
285 1ZOY UQ1 0.01472 0.41667 8.81057
286 1M7G ADX 0.0001062 0.48835 9.00474
287 1M7G ADP 0.0001522 0.47824 9.00474
288 1M7G AV2 0.000001735 0.47067 9.00474
289 1UAD GNP 0.00000000006889 0.74172 9.09091
290 5HR5 ADP 0.0004181 0.42893 9.22787
291 5IRR GSP 0.00000002878 0.62192 9.2511
292 2Q2Y ADP 0.001056 0.45534 9.2511
293 2Q2Y MKR 0.001204 0.45163 9.2511
294 3LRE ADP 0.000001122 0.42781 9.2511
295 2BEK ATP 0.00131 0.42776 9.2511
296 4YMU ATP 0.00003874 0.4241 9.2511
297 1YQT ADP 0.00003306 0.41157 9.2511
298 3DKP ADP 0.0004078 0.40497 9.2511
299 2PL3 ADP 0.0003844 0.40117 9.2511
300 2WJH GDP 0.0000000005835 0.62308 9.63855
301 2WJH FLC 0.0000003605 0.53276 9.63855
302 4BQS ADP 0.00003546 0.53486 9.65909
303 4BQS K2Q 0.0009776 0.45196 9.65909
304 1IHU ADP 0.0002107 0.46292 9.69163
305 1IHU AF3 0.0002285 0.45938 9.69163
306 1RRC ADP 0.000005358 0.41699 9.69163
307 2WHX ADP 0.00002433 0.4127 9.69163
308 1ZC3 GNP 0.00000000009337 0.73935 9.73451
309 5WDR GNP 0.00000000002973 0.76052 9.94152
310 1RJ9 GCP 0.00001296 0.54494 10.1322
311 2IYL GDP 0.000002516 0.48746 10.1322
312 1X6V ADP 0.0001148 0.48351 10.1322
313 4RZ3 ADP 0.0002256 0.44292 10.1322
314 2Y65 ADP 0.000003052 0.43095 10.1322
315 1F9V ADP 0.00001152 0.42571 10.1322
316 1SVI GDP 0.000000005089 0.56291 10.2564
317 1DS6 GDP 0.000000004113 0.57616 10.4167
318 1WDT GTP 0.0000000007259 0.70724 10.5727
319 4YDS ATP 0.00008957 0.40796 10.5727
320 1LVG ADP 0.000000617 0.46889 10.6061
321 3Q85 GNP 0.00000000002789 0.64079 10.6509
322 4WOP CTP 0.0004742 0.44094 10.6667
323 2KIN ADP 0.000001207 0.42659 11
324 1W0J ADP 0.00007238 0.45295 11.0132
325 5J1S ATP 0.001501 0.42895 11.0132
326 2CK3 ANP 0.002607 0.42247 11.0132
327 1W0J ADP BEF 0.002565 0.40585 11.0132
328 2CK3 ADP 0.003169 0.40573 11.0132
329 2OFW ADX 0.0001158 0.49696 11.0577
330 2IXE ATP 0.0006057 0.44173 11.4537
331 3QF7 ANP 0.0005908 0.42969 12
332 4J0Q GDP 0.000000000002664 0.89811 12.3348
333 1OFH ADP 0.0006537 0.41306 12.6437
334 3VMF GTP 0.000000000005467 0.78836 12.7753
335 3WXM GTP 0.000000000009075 0.77903 12.7753
336 3WE0 FAD 0.01384 0.40988 12.7753
337 2PEZ DAT 0.0001393 0.48481 12.8492
338 2PEZ GGZ 0.0001393 0.48481 12.8492
339 1SKQ GDP 0.0000000000634 0.61711 13.2159
340 3ZFD ANP 0.0000005044 0.52462 13.2159
341 4QOS ADP 0.0007572 0.45959 13.2159
342 2QZ4 ADP 0.000225 0.42887 13.2159
343 3RAB GNP 0.000000000009718 0.77777 13.6095
344 2XTZ GSP 0.000000000001365 0.8139 13.6564
345 4E03 ADP 0.0000615 0.44305 14.0777
346 5IFS ADP 0.000366 0.42043 14.0969
347 3W5J GDP 0.00000005187 0.48698 14.2157
348 3REF GDP 0.00000001314 0.63611 14.433
349 4D0G GTP 0.0000000001505 0.717 14.4928
350 4NCN GTP 0.000000000004286 0.78538 14.5374
351 4TMZ GSP 0.0000000000134 0.76463 14.5374
352 5L3S GNP 0.000002793 0.54408 14.978
353 5L3W GDP 0.000008219 0.4835 14.978
354 1X1R GDP 0.000000001416 0.68904 15.1685
355 3EC1 GDP 0.0000000002318 0.63103 15.4185
356 4P4T GDP 0.0000004596 0.58556 15.4185
357 2CE7 ADP 0.000302 0.42244 15.4185
358 2HCJ GDP 0.000000000006773 0.64473 16.2162
359 5CK5 GDP 0.000000002817 0.57059 17.1806
360 1GOT GDP 0.00000004607 0.6134 17.6211
361 1FQJ ALF 0.000000009579 0.74359 18.0617
362 1FQK GDP 0.000000002818 0.66725 18.0617
363 1FQJ GDP 0.000000001839 0.65587 18.0617
364 1FQK ALF 0.00000002372 0.48591 18.0617
365 3QKT ANP 0.0007067 0.44276 18.0617
366 4DID GDP 0.00000003143 0.55885 18.1347
367 1A4R GDP 0.000000007469 0.62748 18.3246
368 1A4R GNH 0.00000001518 0.60631 18.3246
369 1GRN GDP 0.0000001146 0.57101 18.3246
370 2NGR GDP 0.00000003128 0.56179 18.3246
371 4ITR GDP 0.0000005731 0.55112 18.3246
372 2NGR AF3 0.0000004084 0.48793 18.3246
373 1GRN AF3 0.0000009926 0.47679 18.3246
374 2WMO GTP 0.0000000009349 0.62589 18.4211
375 3ZS9 ADP ALF 0.00003888 0.49995 18.4211
376 1NF3 GNP 0.000000002105 0.67877 18.4615
377 2ODE ALF GDP 0.000000000004071 0.80397 18.5022
378 1BH2 GSP 0.00000000001239 0.78318 18.5022
379 1Y3A GDP 0.00000002203 0.62981 18.5022
380 5KDO GDP 0.0000000342 0.60909 18.5022
381 1GP2 GDP 0.00000006286 0.5946 18.5022
382 2VVG ADP 0.0000009561 0.43139 18.5022
383 1AZT GSP 0.00000000000316 0.8087 18.9427
384 1SVK ALF GDP 0.000000000007769 0.795 18.9427
385 1CS4 GSP 0.000000000002201 0.70663 18.9427
386 2J5V PCA 0.03516 0.40966 18.9427
387 4X8O AP5 0.001456 0.45441 19.1589
388 4YC7 GNP 0.000000003529 0.6599 19.337
389 2C9O ADP 0.0009925 0.42725 19.3833
390 2BCG GDP 0.000000019 0.60896 19.4175
391 1CXZ GSP 0.0000000002868 0.70534 19.7674
392 3A1S GDP 0.0000006746 0.52345 20.155
393 5UWP GNP 0.00000000001356 0.77833 20.2643
394 5DIF GNP 0.00000000001329 0.77542 20.2643
395 5UWW GNP 0.0000000000133 0.7754 20.2643
396 5UWU GNP 0.00000000001346 0.77518 20.2643
397 5UWO GNP 0.00000000001361 0.77498 20.2643
398 5UWI GNP 0.00000000001387 0.77462 20.2643
399 5UWT GNP 0.00000000001465 0.77361 20.2643
400 5UWH GNP 0.00000000001575 0.77227 20.2643
401 5DHF GNP 0.00000000001646 0.77146 20.2643
402 5DI9 GNP 0.00000000002179 0.7695 20.2643
403 5UWS GNP 0.00000000002227 0.7691 20.2643
404 5UWJ GNP 0.0000000000152 0.69209 20.2643
405 3ZIA ADP 0.0001471 0.44168 20.6349
406 3ZIA ATP 0.0000711 0.43895 20.6349
407 3GJ8 GDP 0.00000000007453 0.79771 20.8145
408 3GJ0 GDP 0.0000000001987 0.7906 20.8145
409 3GJ5 GDP 0.0000000001009 0.64287 20.8145
410 3GJ3 GDP 0.00000000009167 0.62814 20.8145
411 3GJ7 GDP 0.0000000002198 0.61774 20.8145
412 3WYF GTP 0.00000000002283 0.76864 21.0046
413 3M1I GTP 0.00000000002633 0.76277 21.0046
414 3GJ4 GDP 0.0000000002664 0.61542 21.2121
415 4HAT GNP 0.00000000001392 0.77784 21.2963
416 1IBR GNP 0.00000000002618 0.76287 21.2963
417 3GJX GTP 0.00000000004692 0.75208 21.2963
418 3CH5 GDP 0.00000000007554 0.64667 21.2963
419 5BXQ GDP 0.0000000001039 0.64239 21.2963
420 1TAD ALF 0.000000000006957 0.79396 21.5859
421 1TAD GDP 0.000000000006957 0.79396 21.5859
422 1YZN GNP 0.00000000002448 0.76411 21.6216
423 3CX8 GSP 0.000000000001082 0.82871 22.0264
424 1ZCB GDP 0.000000002897 0.6729 22.0264
425 3AB3 GDP 0.000000003858 0.64735 22.0264
426 5BQ5 ADP BEF 0.0003507 0.47511 22.2222
427 5M7P ADP 0.0005204 0.43283 22.467
428 5KSZ GCP 0.000001444 0.51284 22.9075
429 3CPJ GDP 0.00000001762 0.58871 23.7668
430 1WF3 GNP 0.00000000008514 0.74105 24.2291
431 5IRC GDP 0.0000002866 0.54082 24.2291
432 4OI4 ATP 0.0007621 0.43951 24.3478
433 3VX3 ADP 0.0003933 0.43854 24.6696
434 2OM2 GDP 0.00000002254 0.63421 25
435 3WYG GTP 0.00000000002196 0.76936 25.2747
436 2EW1 GNP 0.000000000003123 0.79115 25.3731
437 5UQW GDP 0.0000000007635 0.6943 25.3968
438 3RWO GDP 0.000000001718 0.68251 25.4054
439 2CJW GDP 0.00000000006872 0.62944 25.5208
440 1R6B ADP 0.0005794 0.40838 25.5507
441 3TNF GNP 0.000000000006134 0.79308 25.8621
442 3QBT GNP 0.000000000001755 0.74178 25.8621
443 4LHW GNP 0.0000000001122 0.67538 25.8621
444 5TAR GDP 0.000000002927 0.70036 25.9459
445 5TB5 GDP 0.000000001521 0.61486 25.9459
446 1WA5 GTP 0.00000000004304 0.76575 26.1364
447 1OIX GDP 0.0000000001693 0.72517 26.178
448 1OIV GDP 0.000000004899 0.66323 26.178
449 4KVG GTP 0.00000000009899 0.73505 26.7857
450 4K81 GTP 0.0000000001862 0.72962 26.9006
451 2VOH CIT 0.0141 0.41575 26.9231
452 1LFD GNP 0.00000000003695 0.75319 26.9461
453 4DSU GDP 0.0000000009167 0.69708 26.9841
454 1NRJ GTP 0.000000000008576 0.75642 27.0642
455 2G77 GDP 0.00000000001827 0.78826 27.2727
456 2G77 AF3 0.00000006958 0.69813 27.2727
457 5KSP GDP 0.0000003179 0.52343 27.3684
458 5E95 GDP 0.00000002299 0.59639 27.381
459 1KAO GDP 0.00000001422 0.60186 27.5449
460 1F2U ATP 0.001036 0.4392 27.7027
461 1NVV GNP 0.00000000002829 0.76143 27.7108
462 2UZI GTP 0.00000000005234 0.74678 27.7108
463 3KUD GDP 0.000000005705 0.64094 27.7108
464 1WQ1 GDP 0.00000003028 0.62402 27.7108
465 1WQ1 AF3 0.000000284 0.45958 27.7108
466 5JCZ GDP 0.000000006918 0.62649 27.933
467 3PQC GDP 0.0000001562 0.54731 28.2051
468 4LX0 BEF GDP 0.000000000005609 0.79137 28.2486
469 1NVU GTP 0.00000000002777 0.76178 28.3133
470 5O2T GSP 0.0000000001181 0.735 28.4024
471 1VG8 GNP 0.000000000002094 0.8096 28.5024
472 1VG0 GDP 0.000000002048 0.62238 28.5024
473 1Z06 GNP 0.000000000002385 0.79992 28.5714
474 5M04 GDP 0.000000000002357 0.65808 28.6344
475 1TQ4 GDP 0.00000008347 0.61002 28.6344
476 1TU3 GNP 0.000000000009615 0.77796 28.655
477 5XCO GDP 0.000000003875 0.61407 28.655
478 3T5G GDP 0.0000000008973 0.62345 28.7293
479 2EFE GNH 0.00000000265 0.6197 28.7293
480 2HT6 GDP 0.000000000005749 0.64486 28.7356
481 1Z0J GTP 0.000000000003435 0.80045 28.8235
482 1YVD GNP 0.000000000004357 0.79253 28.9941
483 2HV8 GTP 0.0000000001657 0.72556 29.0698
484 1XTQ GDP 0.0000000003612 0.70465 29.3785
485 1R2Q GNP 0.000000000005369 0.81353 29.4118
486 1EK0 GNP 0.000000000005254 0.78909 29.4118
487 1Z08 GNP 0.000000002662 0.66829 29.4118
488 5UFQ GNP 0.0000000008656 0.69513 29.5181
489 5SZH GNP 0.000000000007978 0.78486 29.5567
490 3E5H GNP 0.00000000002534 0.76013 29.7753
491 2D7C GTP 0.00000000003618 0.75357 29.9401
492 1E96 GTP 0.000000001543 0.6845 30.2083
493 3SBD GNP 0.0000000006232 0.70118 30.4813
494 3X1Z GNP 0.0000000000669 0.74865 30.5389
495 4HDQ GNP 0.0000000002126 0.72412 30.5389
496 3TKL GTP 0.00000000004953 0.74438 30.6122
497 1GUA GNP 0.00000000004545 0.67597 31.1377
498 1MH1 GNP 0.0000000004406 0.71064 31.1828
499 5KUT GDP 0.00000008762 0.53945 31.2169
500 1VG1 GDP 0.0000000001232 0.63591 32.4324
501 1VG9 GDP 0.0000000002467 0.62795 32.4324
502 3SFV GDP 0.00000004575 0.6038 32.5967
503 1S8F GDP 0.0000000003848 0.71612 32.7684
504 1HE1 GDP 0.0000004905 0.5773 32.9545
505 1HE1 AF3 0.00002854 0.55506 32.9545
506 4B47 GDP 0.000000000002803 0.65595 33.0396
507 2FH5 GTP 0.000000000001562 0.7855 33.1776
508 5UWR GNP 0.00000000001369 0.77486 33.3333
509 2V7Q ATP 0.00004609 0.45327 33.3333
510 1Z0K GTP 0.000000000006133 0.77886 33.7209
511 1Z2A GDP 0.00000002434 0.61125 33.9286
512 3NKV GNP 0.00000000003535 0.754 34.2857
513 1KY3 GDP 0.000000002602 0.61879 34.6154
514 1KK1 GNP 0.00000000003178 0.62585 36.1233
515 1G16 GDP 0.0000000636 0.60756 37.0588
516 2GJ8 ALF GDP 0.00000000001147 0.69624 40.1163
517 5UWQ GNP 0.00000000001242 0.6951 40.9091
518 1F6B GDP 0.00000000001826 0.66627 40.9091
519 1M2O GNP 0.000000000001004 0.81956 41.5789
520 1ZD9 GDP 0.000000003637 0.67684 43.0851
521 1ZJ6 G3D 0.00000000001254 0.67043 43.8503
522 1YZG GDP 0.000000000009366 0.67448 46.3687
523 2QTV GNP 0.0000000000008212 0.81944 47.3054
524 3AQ4 GDP 0.000000000008309 0.67437 49.4565
Pocket No.: 2; Query (leader) PDB : 4M9Q; Ligand: GNP; Similar sites found: 1
This union binding pocket(no: 2) in the query (biounit: 4m9q.bio3) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2F5X ASP 0.03248 0.40056 4.84582
Pocket No.: 3; Query (leader) PDB : 4M9Q; Ligand: GNP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 4m9q.bio2) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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