Receptor
PDB id Resolution Class Description Source Keywords
4NTX 2.27 Å NON-ENZYME: OTHER STRUCTURE OF ACID-SENSING ION CHANNEL IN COMPLEX WITH SNAKE AMILORIDE GALLUS GALLUS KUNITZ PHOSPHOLIPASE A2-LIKE ION CHANNEL NOCICEPTION MEMTRANSPORT PROTEIN-TOXIN COMPLEX
Ref.: X-RAY STRUCTURE OF ACID-SENSING ION CHANNEL 1-SNAKE COMPLEX REVEALS OPEN STATE OF A NA(+)-SELECTIVE CHA CELL(CAMBRIDGE,MASS.) V. 156 717 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
P6G A:506;
Invalid;
none;
submit data
282.331 C12 H26 O7 C(COC...
NAG A:502;
A:501;
Invalid;
Invalid;
none;
none;
submit data
221.208 C8 H15 N O6 CC(=O...
AMR A:507;
A:509;
A:508;
Valid;
Valid;
Valid;
none;
none;
none;
submit data
229.627 C6 H8 Cl N7 O c1(c(...
CL A:503;
Invalid;
none;
submit data
35.453 Cl [Cl-]
NA C:201;
A:504;
A:505;
Part of Protein;
Invalid;
Part of Protein;
none;
none;
none;
submit data
22.99 Na [Na+]
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4NTX 2.27 Å NON-ENZYME: OTHER STRUCTURE OF ACID-SENSING ION CHANNEL IN COMPLEX WITH SNAKE AMILORIDE GALLUS GALLUS KUNITZ PHOSPHOLIPASE A2-LIKE ION CHANNEL NOCICEPTION MEMTRANSPORT PROTEIN-TOXIN COMPLEX
Ref.: X-RAY STRUCTURE OF ACID-SENSING ION CHANNEL 1-SNAKE COMPLEX REVEALS OPEN STATE OF A NA(+)-SELECTIVE CHA CELL(CAMBRIDGE,MASS.) V. 156 717 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 4NTX - AMR C6 H8 Cl N7 O c1(c(nc(c(....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 4NTX - AMR C6 H8 Cl N7 O c1(c(nc(c(....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 4NTX - AMR C6 H8 Cl N7 O c1(c(nc(c(....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: AMR; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 AMR 1 1
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4NTX; Ligand: AMR; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 4ntx.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 4NTX; Ligand: AMR; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 4ntx.bio1) has 3 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 4NTX; Ligand: AMR; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 4ntx.bio1) has 3 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 4NTX; Ligand: AMR; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 4ntx.bio2) has 9 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 4NTX; Ligand: AMR; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 4ntx.bio2) has 9 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 4NTX; Ligand: AMR; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 4ntx.bio2) has 9 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 4NTX; Ligand: AMR; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 4ntx.bio2) has 6 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 8; Query (leader) PDB : 4NTX; Ligand: AMR; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 8) in the query (biounit: 4ntx.bio2) has 6 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 9; Query (leader) PDB : 4NTX; Ligand: AMR; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 9) in the query (biounit: 4ntx.bio2) has 6 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 10; Query (leader) PDB : 4NTX; Ligand: AMR; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 10) in the query (biounit: 4ntx.bio2) has 6 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 11; Query (leader) PDB : 4NTX; Ligand: AMR; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 11) in the query (biounit: 4ntx.bio2) has 6 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 12; Query (leader) PDB : 4NTX; Ligand: AMR; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 12) in the query (biounit: 4ntx.bio2) has 6 residues
No: Leader PDB Ligand Sequence Similarity
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