Receptor
PDB id Resolution Class Description Source Keywords
4OI4 2.4 Å EC: 2.7.1.78 PROTEIN COMPLEX OF CLP1 BOUND TO ATP AND MG2+ WITH PCF11DELTAN454DELTAC563 OF S. CEREVISIAE SACCHAROMYCES CEREVISIAE POLYNUCLEOTIDE KINASE CLP1 PCF11 CLEAVAGE FACTOR IA 3-prime -EPROCESSING TRANSCRIPTION
Ref.: RNA SPECIFICITY AND REGULATION OF CATALYSIS IN THE EUKARYOTIC POLYNUCLEOTIDE KINASE CLP1. MOL.CELL V. 54 975 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL A:503;
C:504;
C:503;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
MG A:502;
C:502;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
ATP C:501;
A:501;
Valid;
Valid;
none;
none;
submit data
507.181 C10 H16 N5 O13 P3 c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4OI4 2.4 Å EC: 2.7.1.78 PROTEIN COMPLEX OF CLP1 BOUND TO ATP AND MG2+ WITH PCF11DELTAN454DELTAC563 OF S. CEREVISIAE SACCHAROMYCES CEREVISIAE POLYNUCLEOTIDE KINASE CLP1 PCF11 CLEAVAGE FACTOR IA 3-prime -EPROCESSING TRANSCRIPTION
Ref.: RNA SPECIFICITY AND REGULATION OF CATALYSIS IN THE EUKARYOTIC POLYNUCLEOTIDE KINASE CLP1. MOL.CELL V. 54 975 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 4OI4 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 4OI4 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 4OI4 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ATP; Similar ligands found: 404
No: Ligand ECFP6 Tc MDL keys Tc
1 ATP 1 1
2 AQP 0.985507 1
3 5FA 0.985507 1
4 B4P 0.927536 0.971831
5 AP5 0.927536 0.971831
6 BA3 0.913043 0.971831
7 ADP 0.9 1
8 A2D 0.884058 0.971831
9 SAP 0.84 0.945946
10 AGS 0.84 0.945946
11 AN2 0.810811 0.985915
12 25L 0.809524 0.985915
13 APR 0.802632 0.971831
14 AR6 0.802632 0.971831
15 M33 0.8 0.958333
16 TAT 0.794872 0.958904
17 ACQ 0.794872 0.972222
18 AD9 0.792208 0.972222
19 ACP 0.789474 0.972222
20 A 0.788732 0.971429
21 AMP 0.788732 0.971429
22 ANP 0.772152 0.972222
23 ADX 0.753247 0.873418
24 CA0 0.753247 0.945205
25 A22 0.746988 0.985915
26 50T 0.74359 0.958333
27 APC 0.734177 0.958904
28 PRX 0.734177 0.893333
29 ABM 0.733333 0.917808
30 ATF 0.731707 0.958904
31 ITT 0.730769 0.943662
32 7D4 0.730769 0.905405
33 ADQ 0.729412 0.945205
34 AMP MG 0.72 0.891892
35 AP2 0.714286 0.958904
36 A12 0.714286 0.958904
37 A1R 0.709302 0.907895
38 SRA 0.706667 0.918919
39 5AL 0.698795 0.931507
40 OAD 0.693182 0.945205
41 ADP MG 0.6875 0.905405
42 AU1 0.6875 0.972222
43 SRP 0.682353 0.906667
44 G5P 0.680851 0.921053
45 BEF ADP 0.679012 0.881579
46 ADP BEF 0.679012 0.881579
47 25A 0.678161 0.971831
48 3OD 0.677778 0.945205
49 4AD 0.670455 0.92
50 G3A 0.670213 0.921053
51 00A 0.662921 0.883117
52 ADV 0.662651 0.932432
53 ADP PO3 0.662651 0.943662
54 RBY 0.662651 0.932432
55 BIS 0.659341 0.933333
56 5SV 0.659091 0.848101
57 8QN 0.659091 0.931507
58 OOB 0.659091 0.931507
59 GTA 0.65625 0.886076
60 ATP MG 0.654762 0.905405
61 UP5 0.653061 0.92
62 AMO 0.651685 0.932432
63 PAJ 0.651685 0.884615
64 2A5 0.650602 0.918919
65 MAP 0.647727 0.945946
66 3AT 0.647059 0.971831
67 AHX 0.644444 0.896104
68 DLL 0.644444 0.931507
69 PAP 0.642857 0.985714
70 ATR 0.642857 0.971429
71 PTJ 0.641304 0.896104
72 7D3 0.6375 0.905405
73 3UK 0.637363 0.918919
74 SON 0.634146 0.932432
75 A4P 0.633663 0.843373
76 ALF ADP 0.632184 0.87013
77 ADP ALF 0.632184 0.87013
78 LAD 0.630435 0.860759
79 WAQ 0.630435 0.883117
80 PR8 0.630435 0.85
81 AFH 0.628866 0.884615
82 DTP 0.627907 0.905405
83 GAP 0.627907 0.893333
84 ANP MG 0.625 0.894737
85 VO4 ADP 0.625 0.931507
86 ADP VO4 0.625 0.931507
87 1ZZ 0.623656 0.839506
88 TXA 0.623656 0.932432
89 FYA 0.623656 0.905405
90 ME8 0.623656 0.839506
91 NB8 0.623656 0.896104
92 T5A 0.621359 0.841463
93 RAB 0.619718 0.84507
94 ADN 0.619718 0.84507
95 XYA 0.619718 0.84507
96 9SN 0.610526 0.871795
97 48N 0.61 0.896104
98 AP0 0.607843 0.896104
99 FA5 0.604167 0.906667
100 YAP 0.604167 0.894737
101 TXD 0.60396 0.907895
102 6V0 0.60396 0.896104
103 NXX 0.60396 0.932432
104 NAI 0.60396 0.907895
105 DND 0.60396 0.932432
106 NAX 0.60396 0.873418
107 ADP BMA 0.602151 0.918919
108 A2R 0.6 0.985915
109 OMR 0.598039 0.851852
110 TXE 0.598039 0.907895
111 XAH 0.597938 0.839506
112 DAL AMP 0.593407 0.905405
113 7DT 0.593023 0.985714
114 AOC 0.592593 0.821918
115 4UV 0.591837 0.894737
116 DDS 0.590909 0.878378
117 139 0.590476 0.873418
118 CNA 0.584906 0.932432
119 6AD 0.58427 0.909091
120 5AS 0.583333 0.77907
121 5N5 0.581081 0.819444
122 4UU 0.58 0.894737
123 4TC 0.576923 0.896104
124 ADJ 0.575472 0.851852
125 5CD 0.573333 0.805556
126 A4D 0.573333 0.819444
127 RGT 0.571429 0.958904
128 A3P 0.571429 0.971429
129 7D5 0.56962 0.878378
130 LAQ 0.568627 0.839506
131 YLP 0.563107 0.819277
132 A A 0.5625 0.944444
133 UPA 0.561905 0.907895
134 AV2 0.56044 0.917808
135 COD 0.559633 0.811765
136 4UW 0.557692 0.860759
137 JB6 0.556701 0.883117
138 3AM 0.555556 0.929577
139 ATP A A A 0.555556 0.930556
140 A2P 0.552941 0.957143
141 TYM 0.552381 0.906667
142 NA7 0.552083 0.958904
143 EP4 0.551282 0.753247
144 MYR AMP 0.55102 0.817073
145 PPS 0.549451 0.873418
146 YLB 0.54717 0.819277
147 YLC 0.54717 0.839506
148 NAD 0.545455 0.931507
149 DAT 0.545455 0.905405
150 G5A 0.544444 0.77907
151 M2T 0.544304 0.734177
152 DTA 0.544304 0.786667
153 3DH 0.54321 0.773333
154 128 0.542857 0.776471
155 AHZ 0.538462 0.817073
156 SSA 0.537634 0.8
157 GTP 0.537634 0.92
158 MTA 0.5375 0.773333
159 IOT 0.537037 0.831325
160 A3D 0.535714 0.918919
161 TYR AMP 0.534653 0.881579
162 AR6 AR6 0.533981 0.917808
163 7MD 0.533981 0.8625
164 YLA 0.53211 0.819277
165 AMP DBH 0.529412 0.893333
166 IMO 0.529412 0.929577
167 TAD 0.528846 0.884615
168 AYB 0.527273 0.809524
169 A5A 0.526882 0.807229
170 TSB 0.526316 0.819277
171 EAD 0.525424 0.873418
172 2AM 0.52439 0.943662
173 6RE 0.52381 0.759494
174 7DD 0.522727 0.985714
175 V3L 0.521739 0.971831
176 AVV 0.520833 0.896104
177 BTX 0.517857 0.841463
178 NAE 0.517241 0.894737
179 54H 0.515789 0.788235
180 VMS 0.515789 0.788235
181 52H 0.515789 0.77907
182 NSS 0.515464 0.8
183 BT5 0.513274 0.831325
184 NAQ 0.512821 0.871795
185 ZAS 0.511905 0.766234
186 A3N 0.511628 0.786667
187 J7C 0.511628 0.769231
188 5X8 0.511111 0.763158
189 53H 0.510417 0.77907
190 5CA 0.510417 0.8
191 ARU 0.510204 0.860759
192 ARG AMP 0.509434 0.829268
193 AF3 ADP 3PG 0.509259 0.8375
194 LA8 ALF 3PG 0.509259 0.8375
195 ALF ADP 3PG 0.509259 0.8375
196 ZID 0.508475 0.918919
197 P1H 0.508197 0.851852
198 OVE 0.505882 0.905405
199 S4M 0.505747 0.666667
200 LPA AMP 0.504673 0.817073
201 7MC 0.504587 0.841463
202 DZD 0.5 0.884615
203 LSS 0.5 0.761364
204 DSZ 0.5 0.8
205 P5A 0.5 0.744444
206 DSH 0.5 0.725
207 FB0 0.5 0.804598
208 MAO 0.5 0.759036
209 NDE 0.495935 0.932432
210 N0B 0.495798 0.819277
211 M24 0.495726 0.85
212 YLY 0.495726 0.809524
213 NJP 0.495575 0.945946
214 NVA LMS 0.494949 0.761364
215 MGP 0.494737 0.884615
216 6C6 0.494624 0.881579
217 NAJ PZO 0.491379 0.848101
218 0WD 0.491228 0.921053
219 LEU LMS 0.49 0.761364
220 6G0 0.489583 0.884615
221 GJV 0.488636 0.75
222 6FA 0.488189 0.841463
223 5AD 0.486842 0.746479
224 GSU 0.485149 0.77907
225 KAA 0.485149 0.752809
226 71V 0.483146 0.907895
227 NEC 0.482759 0.746667
228 A3G 0.482759 0.8
229 NAD IBO 0.482456 0.87013
230 ODP 0.482456 0.909091
231 FAS 0.48062 0.851852
232 FAD 0.48062 0.851852
233 7D7 0.480519 0.743243
234 FDA 0.480315 0.833333
235 N6P 0.48 0.915493
236 2SA 0.479167 0.932432
237 GP3 0.478723 0.921053
238 4TA 0.478261 0.807229
239 G A A A 0.478261 0.871795
240 SFG 0.478261 0.75
241 NPW 0.477876 0.886076
242 NDP 0.477876 0.921053
243 NDC 0.47619 0.871795
244 YSA 0.47619 0.77907
245 MGO 0.474227 0.860759
246 6IA 0.473684 0.8375
247 TXP 0.473684 0.921053
248 GDP 0.473684 0.92
249 NZQ 0.473684 0.909091
250 A7D 0.472527 0.776316
251 SFD 0.469231 0.734043
252 ZDA 0.468085 0.864865
253 SA8 0.468085 0.707317
254 A5D 0.468085 0.786667
255 12D 0.46789 0.785714
256 PGS 0.467391 0.883117
257 MHZ 0.467391 0.697674
258 62F 0.466165 0.8625
259 DA 0.465909 0.878378
260 D5M 0.465909 0.878378
261 GGZ 0.464646 0.825
262 SAH 0.463158 0.74359
263 SAI 0.463158 0.734177
264 NAJ PYZ 0.46281 0.85
265 FAY 0.462687 0.8625
266 Y3J 0.4625 0.726027
267 PO4 PO4 A A A A PO4 0.460784 0.902778
268 AAM 0.460674 0.971429
269 RFL 0.459259 0.821429
270 SMM 0.459184 0.686047
271 AMZ 0.458824 0.916667
272 C2R 0.458824 0.90411
273 SAM 0.458333 0.690476
274 A3S 0.456522 0.810811
275 FNK 0.455224 0.804598
276 7C5 0.453704 0.818182
277 AAT 0.453608 0.707317
278 EEM 0.453608 0.690476
279 XNP 0.452991 0.873418
280 AIR 0.451219 0.901408
281 62X 0.45098 0.666667
282 GSP 0.45 0.873418
283 ETB 0.45 0.833333
284 DCA 0.45 0.823529
285 U A G G 0.449153 0.883117
286 NIA 0.448276 0.822785
287 AMP NAD 0.447154 0.881579
288 A3T 0.446809 0.821918
289 K15 0.446602 0.682353
290 A A A 0.446602 0.905405
291 PUA 0.446281 0.884615
292 6K6 0.445545 0.930556
293 GEK 0.445545 0.7375
294 4YB 0.445455 0.761364
295 S7M 0.444444 0.690476
296 DG1 0.443548 0.921053
297 1DG 0.443548 0.921053
298 Z5A 0.443548 0.77907
299 COA 0.442623 0.823529
300 0T1 0.442623 0.823529
301 WSA 0.442478 0.788235
302 8BR 0.43956 0.906667
303 101 0.438202 0.878378
304 IDP 0.4375 0.918919
305 NAP 0.435484 0.945205
306 APU 0.434783 0.894737
307 A U 0.434783 0.87013
308 7RP 0.433333 0.928571
309 A6D 0.432692 0.722892
310 CAO 0.432 0.795455
311 AMX 0.432 0.833333
312 COS 0.432 0.804598
313 TAP 0.432 0.907895
314 J7V 0.432 0.833333
315 30N 0.432 0.752688
316 V1N 0.431193 0.917808
317 649 0.429825 0.744444
318 P5F 0.429577 0.823529
319 NA0 0.428571 0.932432
320 CMX 0.428571 0.823529
321 7RA 0.428571 0.957747
322 SCO 0.428571 0.823529
323 0UM 0.427184 0.698795
324 GAV 0.427184 0.884615
325 ACK 0.426966 0.861111
326 1RB 0.426966 0.885714
327 QQY 0.426966 0.815789
328 GCP 0.425743 0.896104
329 G1R 0.425743 0.907895
330 FAM 0.425197 0.804598
331 FCX 0.425197 0.795455
332 ACO 0.425197 0.795455
333 GNH 0.424242 0.907895
334 F2N 0.423611 0.813953
335 GDC 0.422018 0.884615
336 GDD 0.422018 0.884615
337 GKE 0.422018 0.884615
338 HAX 0.421875 0.804598
339 3AD 0.421687 0.805556
340 GNP 0.421569 0.896104
341 FA9 0.42069 0.864198
342 KB1 0.420561 0.698795
343 TM1 0.420561 0.77381
344 H6Y 0.42 0.945205
345 2MC 0.419847 0.769231
346 3KK 0.418605 0.804598
347 FYN 0.418605 0.823529
348 S8M 0.417476 0.759494
349 2VA 0.416667 0.8
350 NHD 0.416667 0.905405
351 26A 0.416667 0.763158
352 QQX 0.41573 0.805195
353 SOP 0.415385 0.804598
354 OXK 0.415385 0.804598
355 COK 0.415385 0.804598
356 MCD 0.415385 0.804598
357 CA6 0.415385 0.729167
358 YE1 0.413534 0.813953
359 FAI 0.413043 0.916667
360 AS 0.413043 0.833333
361 RMB 0.413043 0.873239
362 1VU 0.412214 0.795455
363 CO6 0.412214 0.804598
364 CMC 0.412214 0.804598
365 NMX 0.412214 0.76087
366 SXZ 0.411215 0.710843
367 ANZ 0.410714 0.8
368 SCA 0.410448 0.804598
369 PLP AAD 0.409836 0.741573
370 SCD 0.409091 0.823529
371 CAJ 0.409091 0.804598
372 NAD BBN 0.408759 0.841463
373 NVA 2AD 0.408163 0.74359
374 D3Y 0.407767 0.789474
375 CC5 0.407407 0.816901
376 U G A 0.407407 0.839506
377 KH3 0.40708 0.674419
378 SLU 0.406504 0.770115
379 G 0.40625 0.906667
380 5GP 0.40625 0.906667
381 BCO 0.406015 0.804598
382 IVC 0.406015 0.813953
383 A1S 0.406015 0.804598
384 MLC 0.406015 0.804598
385 3HC 0.406015 0.813953
386 1HE 0.406015 0.786517
387 GTG 0.405405 0.886076
388 NMN AMP PO4 0.404959 0.87013
389 3D1 0.404762 0.773333
390 3L1 0.404762 0.773333
391 CMP 0.404255 0.901408
392 2BA 0.404255 0.915493
393 SO8 0.40404 0.789474
394 VRT 0.40404 0.769231
395 MCA 0.402985 0.795455
396 CAA 0.402985 0.813953
397 COO 0.402985 0.804598
398 NAD CJ3 0.402878 0.811765
399 G2R 0.401869 0.884615
400 3NZ 0.401869 0.782051
401 ZZB 0.4 0.77381
402 MC4 0.4 0.76087
403 2FA 0.4 0.813333
404 2CP 0.4 0.795455
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4OI4; Ligand: ATP; Similar sites found: 475
This union binding pocket(no: 1) in the query (biounit: 4oi4.bio2) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2Q2Y ADP 0.008915 0.41091 1.90736
2 2Q2Y MKR 0.008448 0.41091 1.90736
3 4IDN GNP 0.0004604 0.44869 2.6087
4 5K5Z ANP 0.00145 0.41783 2.6087
5 1KK1 GNP 0.0000902 0.40831 2.68293
6 1WDT GTP 0.0006555 0.45049 2.86976
7 3UIE ANP 0.0001073 0.43478 3
8 5X40 ACP 0.003038 0.41101 3.08219
9 2CE7 ADP 0.0004473 0.41002 3.09051
10 1WF3 GNP 0.0005355 0.44749 3.32226
11 3T34 GDP 0.002698 0.41313 3.33333
12 2PEZ DAT 0.007749 0.40571 3.35196
13 5VGR GDP 0.000238 0.47455 3.47826
14 1K6M AGS 0.004149 0.40863 3.47826
15 4YS0 ADP 0.007334 0.40805 3.47826
16 2ZX2 RAM 0.02272 0.40667 3.47826
17 4BAS GNP 0.0004762 0.4382 3.51759
18 5KSZ GCP 0.0002574 0.48341 3.53201
19 1SQ5 ADP 0.0004245 0.47865 3.57143
20 3WY9 GDP 0.0001193 0.51812 3.68664
21 3WYA GDP 0.0001615 0.50491 3.68664
22 2ZPT A3P 0.02222 0.40408 3.72881
23 2ZPA ADP 0.001612 0.40688 3.75276
24 2RCN GDP 0.0003368 0.40036 3.91061
25 3FKQ ATP 0.001632 0.43722 4.02145
26 4QOS ADP 0.001221 0.45184 4.15094
27 3FB4 AP5 0.0005756 0.46322 4.16667
28 3TMK T5A 0.005028 0.40974 4.16667
29 2XT3 ADP 0.00002758 0.56984 4.34783
30 2QN6 GDP 0.00007602 0.52794 4.34783
31 4NON GDP 0.0003123 0.49089 4.34783
32 4MKF AP5 0.0007816 0.45855 4.34783
33 2C9O ADP 0.0004965 0.45145 4.34783
34 1FNN ADP 0.0009057 0.44436 4.34783
35 4WEI GLC GAL 0.006588 0.43788 4.34783
36 4RD0 GDP 0.0005566 0.43533 4.34783
37 2FNA ADP 0.001079 0.43317 4.34783
38 1UKZ ADP 0.00279 0.42603 4.34783
39 4U5X GNP 0.0008509 0.41637 4.34783
40 4ZKD GDP 0.001099 0.41083 4.34783
41 5FG3 GDP 0.0000809 0.41044 4.34783
42 1IN4 ADP 0.001661 0.40664 4.34783
43 1FZQ GDP 0.00007055 0.42403 4.41989
44 4ZI2 GNP 0.0008029 0.43856 4.51128
45 5J1J ANP 0.0001346 0.46666 4.5614
46 3Q9L ATP 0.000621 0.45596 4.61538
47 1GRN GDP 0.00147 0.43926 4.71204
48 1A4R GDP 0.001112 0.41215 4.71204
49 1A4R GNH 0.0009211 0.40972 4.71204
50 1YVD GNP 0.001098 0.4162 4.73373
51 4PX9 ADP 0.002959 0.44809 4.79452
52 1NJF AGS 0.001081 0.42435 4.8
53 1NJF ADP 0.001823 0.40517 4.8
54 4WOP CTP 0.00213 0.42437 4.88889
55 2GCO GNP 0.000723 0.4128 4.97512
56 2GCN GDP 0.003973 0.40127 4.97512
57 1QF9 C5P 0.001776 0.43825 5.15464
58 2OBM ADP 0.001461 0.47835 5.21739
59 2HF9 GSP 0.0002745 0.47179 5.21739
60 2DPY ADP 0.001319 0.47157 5.21739
61 1W5T ADP 0.0004605 0.46176 5.21739
62 4PFO ADP 0.0002835 0.45722 5.21739
63 1G41 ADP 0.001735 0.44472 5.21739
64 2VB6 ADP BEF 0.0005964 0.44009 5.21739
65 4V03 ADP 0.002414 0.43802 5.21739
66 1W5T ANP 0.001053 0.43746 5.21739
67 1OXV ANP 0.00006678 0.4221 5.21739
68 1F9V ADP 0.00002479 0.40886 5.21739
69 5KSP GDP 0.0003494 0.48269 5.26316
70 4DID GDP 0.0009939 0.46099 5.26316
71 3FVQ ATP 0.0007577 0.44359 5.29248
72 2CHG ANP 0.0004653 0.46156 5.30973
73 1KSH GDP 0.0004613 0.43277 5.37634
74 3Q72 GNP 0.0001177 0.4034 5.42169
75 1V6A TRE 0.0323 0.40046 5.42169
76 1F6B GDP 0.0002149 0.41655 5.55556
77 3DZD ADP 0.0007636 0.40818 5.70652
78 2ZTS ADP 0.0006878 0.44958 5.73951
79 1VG8 GNP 0.001123 0.43405 5.7971
80 1BO4 COA 0.01074 0.41559 5.95238
81 5LTJ ADP 0.0007554 0.46669 5.96026
82 5LTJ BEF 0.0112 0.42083 5.96026
83 2EW1 GNP 0.00245 0.41485 5.97015
84 3KTA AP5 0.000599 0.46135 6.04396
85 1XEX ATP 0.001618 0.40966 6.04396
86 3T5G GDP 0.0003544 0.41211 6.07735
87 1GOJ ADP 0.00001977 0.58274 6.08696
88 3U6B GDP 0.00006758 0.5305 6.08696
89 2ZR9 DTP 0.000133 0.50904 6.08696
90 4G5G GDP 0.0001507 0.50638 6.08696
91 3U6K GDP 0.0002272 0.49765 6.08696
92 4LPS GDP 0.0004304 0.47836 6.08696
93 4LYA ATP 0.001179 0.45745 6.08696
94 5JCP GDP ALF 0.0006999 0.45364 6.08696
95 2BEK ATP 0.0005642 0.44499 6.08696
96 3VMF GTP 0.00059 0.44399 6.08696
97 4A4Z ANP 0.003775 0.43788 6.08696
98 1JWY ADP 0.00005137 0.43588 6.08696
99 3WXM GTP 0.001005 0.43436 6.08696
100 4H1V GNP 0.001999 0.4333 6.08696
101 1D2N ANP 0.0005831 0.42953 6.08696
102 1NF3 GNP 0.0005304 0.42847 6.08696
103 1JWY GDP 0.0002111 0.42606 6.08696
104 4R2I ANP 0.01244 0.42122 6.08696
105 1TX4 ALF GDP 0.002034 0.41818 6.08696
106 1KMQ GNP 0.002361 0.41552 6.08696
107 2VF7 ADP 0.0003015 0.40921 6.08696
108 5L2R MLA 0.03107 0.40623 6.08696
109 1OW3 GDP 0.001165 0.40512 6.08696
110 5HPY GDP 0.001523 0.40109 6.08696
111 2CJW GDP 0.0003394 0.48912 6.25
112 2WMO GTP 0.0003367 0.47796 6.31579
113 1GWN GTP 0.0005892 0.42906 6.34146
114 2PL3 ADP 0.001025 0.47123 6.35593
115 4YLG GDP 0.0004427 0.46252 6.35838
116 1VG1 GDP 0.0003532 0.40705 6.48649
117 3B7G ANP 0.0009218 0.46256 6.52174
118 5GJC ATP 0.0001776 0.50289 6.56109
119 3WYG GTP 0.003371 0.41561 6.59341
120 1KY3 GDP 0.0008592 0.40603 6.59341
121 1AZT GSP 0.0007659 0.40512 6.71642
122 2OFW ADX 0.002842 0.43166 6.73077
123 1ZC3 GNP 0.001827 0.42521 6.85714
124 5BQ5 ADP BEF 0.002369 0.4384 6.87831
125 2HT6 GDP 0.0001606 0.40089 6.89655
126 4ZNL BEF ADP 0.00005354 0.52161 6.95652
127 1SKQ GDP 0.0001342 0.51555 6.95652
128 1V8K ANP 0.00009849 0.51542 6.95652
129 5JBQ GDP 0.0001208 0.51108 6.95652
130 2GDJ ANP 0.0002263 0.49773 6.95652
131 2BVN GNP 0.0001354 0.49081 6.95652
132 4TMZ GSP 0.0006719 0.43796 6.95652
133 4NCN GTP 0.0007755 0.4354 6.95652
134 3QKT ANP 0.001456 0.42595 6.95652
135 3REF GDP 0.002019 0.42177 6.95652
136 1F5N GNP 0.0007254 0.41798 6.95652
137 1OS1 PYR 0.004639 0.41261 6.95652
138 1OS1 ATP 0.0043 0.41261 6.95652
139 5TSH ANP 0.0001734 0.41033 6.95652
140 1D8T GDP 0.0001425 0.4096 6.95652
141 1T5C ADP 0.000006335 0.404 6.95652
142 1M7B GTP 0.000552 0.44948 7.06522
143 4V0K GDP 0.001928 0.41285 7.10059
144 5GOE GDP 0.000204 0.48811 7.109
145 1KAO GDP 0.001607 0.40114 7.18563
146 3NHB ADP 0.0001146 0.53148 7.18954
147 3KUD GDP 0.002154 0.40649 7.22892
148 1WQ1 GDP 0.004316 0.40473 7.22892
149 1XTQ GDP 0.001188 0.42778 7.34463
150 2WJG GDP 0.0003459 0.48871 7.44681
151 5N69 ADP 0.0001226 0.49278 7.53769
152 1CS4 GSP 0.0005305 0.41578 7.55556
153 1M7G ADX 0.003948 0.41695 7.58294
154 1M7G ADP 0.003441 0.4167 7.58294
155 1M7G AV2 0.00008886 0.41058 7.58294
156 2ZEJ GDP 0.002841 0.4172 7.6087
157 1B0U ATP 0.001715 0.4405 7.63359
158 5GVR LMR 0.0003905 0.50822 7.69231
159 1G6H ADP 0.00001867 0.57972 7.7821
160 4IEE AGS 0.000144 0.51401 7.82609
161 2X77 GDP 0.0001208 0.50472 7.82609
162 4AG5 ADP 0.0003838 0.5042 7.82609
163 2ZFI ADP 0.0001878 0.5017 7.82609
164 1S9D GDP 0.0004132 0.47921 7.82609
165 5LB3 ADP 0.001707 0.46009 7.82609
166 2XTZ GSP 0.0003776 0.45204 7.82609
167 4PC3 GDP 0.000993 0.45133 7.82609
168 2C78 GNP 0.0005688 0.44484 7.82609
169 2C77 GNP 0.0004091 0.43456 7.82609
170 3BOS CDP 0.00006177 0.42835 7.82609
171 3M1I GTP 0.001573 0.42793 7.82609
172 1Z06 GNP 0.0008938 0.42587 7.82609
173 2J59 GTP 0.001598 0.42249 7.82609
174 1O3Y GTP 0.001655 0.42186 7.82609
175 3WYF GTP 0.00246 0.42136 7.82609
176 4IOK ADP 0.002773 0.41917 7.82609
177 1D2E GDP 0.0005003 0.41198 7.82609
178 3W5J GDP 0.000005608 0.41058 7.82609
179 5O2T GSP 0.001403 0.40615 7.82609
180 2Y65 ADP 0.00001769 0.40189 7.82609
181 1RE0 GDP 0.0001574 0.40167 7.82609
182 4IOK XPO 0.005698 0.40142 7.82609
183 2UZI GTP 0.0009503 0.43538 7.89474
184 1JI0 ATP 0.00009129 0.53134 7.91667
185 5KUT GDP 0.0004859 0.40254 7.93651
186 4BQS ADP 0.0001983 0.50054 7.95455
187 1ZJ6 G3D 0.0001335 0.50265 8.02139
188 1CXZ GSP 0.001197 0.42221 8.13953
189 4K81 GTP 0.000772 0.44251 8.18713
190 3Q85 GNP 0.0001823 0.40839 8.28402
191 1RYH GNP 0.0002861 0.41393 8.37438
192 2WJH GDP 0.0002689 0.41207 8.43373
193 2WJH FLC 0.0004745 0.40885 8.43373
194 2AWN ADP 0.00000875 0.60328 8.66142
195 4PPF FLC 0.000007444 0.59078 8.69565
196 3GJ7 GDP 0.0002768 0.49345 8.69565
197 4HSE ADP 0.0004424 0.47779 8.69565
198 3RC3 ANP 0.002395 0.4527 8.69565
199 5IRR GSP 0.0007111 0.44077 8.69565
200 5XDR ADP 0.003068 0.43759 8.69565
201 5JCZ GDP 0.001772 0.43162 8.69565
202 5EE5 GTP 0.001378 0.42873 8.69565
203 1NVU GTP 0.001859 0.4249 8.69565
204 1VHT BA3 0.0001661 0.42394 8.69565
205 4LX0 BEF GDP 0.002192 0.4219 8.69565
206 1IHU ADP 0.001972 0.41873 8.69565
207 1OIX GDP 0.002452 0.41825 8.69565
208 1IHU AF3 0.001662 0.41708 8.69565
209 1DAR GDP 0.0002312 0.40442 8.69565
210 3EWA ANP 0.0002859 0.40239 8.69565
211 2F9L GDP 0.005141 0.4016 8.69565
212 1U8Z GDP 0.005253 0.40121 8.69565
213 1GXU 2HP 0.002523 0.43473 8.79121
214 1Z08 GNP 0.002484 0.4146 8.82353
215 1JJ7 ADP 0.000002861 0.62865 8.84615
216 1E96 GTP 0.00161 0.40966 8.85417
217 2IXE ATP 0.0003669 0.44384 8.85609
218 2FH5 GTP 0.0003758 0.45662 8.8785
219 3A1S GDP 0.0001739 0.49717 8.91473
220 1M2O GNP 0.0004595 0.4485 8.94737
221 2WOJ ADP ALF 0.00007653 0.45477 9.03955
222 3ZS9 ADP ALF 0.0002356 0.43661 9.03955
223 1MH1 GNP 0.00188 0.40118 9.13978
224 2W2X GSP 0.0006034 0.42829 9.18919
225 4LC1 GDP 0.0004355 0.48382 9.19881
226 4DKX GDP 0.0001787 0.50276 9.25926
227 1D5C GDP 0.0005322 0.41902 9.25926
228 1L2T ATP 0.001996 0.41297 9.3617
229 2QG6 NMN 0.000823 0.44134 9.54774
230 2FJU GSP 0.001373 0.41446 9.55056
231 2OG2 MLI 0.00008879 0.54214 9.56522
232 4YDS ATP 0.0001006 0.52917 9.56522
233 3B9Q MLI 0.0003448 0.51287 9.56522
234 1W7J ADP BEF 0.0004019 0.4644 9.56522
235 1TAD GDP 0.000465 0.45341 9.56522
236 1OYY AGS 0.005113 0.43142 9.56522
237 4HI0 GDP 0.001765 0.42786 9.56522
238 2B8W ALF 5GP 0.002243 0.41818 9.56522
239 4XOI GTP 0.001569 0.41622 9.56522
240 1TAD ALF 0.000465 0.41199 9.56522
241 1BG2 ADP 0.000004669 0.40613 9.56522
242 1HE1 GDP 0.001773 0.42778 9.65909
243 2EFE GNH 0.001014 0.40472 9.73783
244 2J5V PCA 0.009384 0.43216 9.80926
245 5UFQ GNP 0.001183 0.41463 9.83607
246 3DC4 ADP 0.00004059 0.41035 9.88372
247 4CVN ADP 0.0001365 0.52233 9.94764
248 3BFV ADP 0.0007127 0.47334 9.9631
249 2NCD ADP 0.00007295 0.54123 10
250 5H67 ATP 0.003601 0.43426 10
251 4GOJ GNP 0.0007842 0.42963 10
252 3A4M ADP 0.00004154 0.41581 10
253 1UAD GNP 0.002057 0.42143 10.101
254 1ZUI SKM 0.00297 0.42735 10.119
255 2C5L GTP 0.001371 0.43043 10.2564
256 2NGR GDP 0.0004223 0.40117 10.2564
257 4C4P GNP 0.002196 0.42187 10.2804
258 3B5J 12D 0.0001445 0.52106 10.2881
259 5E95 GDP 0.001498 0.43889 10.3093
260 3EZ2 ADP 0.001788 0.45909 10.4348
261 5L3V GDP 0.0008957 0.45813 10.4348
262 5L3S GNP 0.0001488 0.4571 10.4348
263 1ZD9 GDP 0.0009724 0.44301 10.4348
264 1NRJ GTP 0.0003251 0.43877 10.4348
265 1CR1 TTP 0.0005569 0.43018 10.4348
266 2GJ8 ALF GDP 0.000369 0.42795 10.4348
267 4YC7 GNP 0.001196 0.42235 10.4348
268 1YZG GDP 0.0001257 0.4217 10.4348
269 4D0N GDP 0.000275 0.40182 10.4348
270 3IO3 ADP 0.002516 0.40042 10.4348
271 1Z0F GDP 0.0004692 0.40044 10.6145
272 4KVG GTP 0.001315 0.42951 10.7143
273 2HCJ GDP 0.00008254 0.40876 10.8108
274 4D0G GTP 0.001462 0.42764 10.8571
275 3DOE GTP 0.0009118 0.43251 10.9375
276 2CBZ ATP 0.000007243 0.60683 10.9705
277 5L3R GCP 0.0002207 0.45026 11.2957
278 4WZ6 ATP 0.00004381 0.55366 11.3043
279 5I0H ADP BEF 0.0001893 0.44904 11.3043
280 4XVU ATP 0.0003708 0.44857 11.3043
281 4XTR ATP 0.0003715 0.44854 11.3043
282 3DEF GDP 0.001811 0.43942 11.3043
283 4PJ3 ANP 0.002354 0.43422 11.3043
284 3ZFD ANP 0.0001185 0.43155 11.3043
285 4XTR ADP 0.001786 0.43147 11.3043
286 1W0J ADP 0.0001784 0.42919 11.3043
287 2BCG GDP 0.002355 0.42622 11.3043
288 1W0J ADP BEF 0.000778 0.41952 11.3043
289 2IS6 ADP 0.0001133 0.41339 11.3043
290 1R0X ATP 0.00007647 0.41256 11.3043
291 1QHH ATP 0.0141 0.40584 11.3043
292 2PZE ATP 0.00001765 0.40429 11.3043
293 5J1S ATP 0.003424 0.40327 11.3043
294 1YZN GNP 0.002005 0.40073 11.3043
295 1YQT ADP 0.00005788 0.40087 11.479
296 1H65 GDP 0.003217 0.40515 11.4815
297 4E03 ADP 0.0005868 0.4006 11.6505
298 3PCR GTP 0.003347 0.40928 11.7284
299 1YZQ GNP 0.0008213 0.43973 11.7647
300 1G3M PCQ 0.01185 0.40445 11.9048
301 3AQ4 GDP 0.0002545 0.48927 11.9565
302 1Y63 ADP 0.0001029 0.41678 11.9565
303 3T12 GDP ALF 0.0009128 0.43622 12.1212
304 3T1O GDP 0.0005544 0.40428 12.1212
305 5M04 GDP 0.00007515 0.52819 12.1739
306 4B47 GDP 0.0001384 0.51488 12.1739
307 1UJ2 C5P 0.0002211 0.46354 12.1739
308 5IRN ADP 0.0005588 0.46272 12.1739
309 2G77 GDP 0.0005291 0.45907 12.1739
310 1UJ2 ADP 0.0003511 0.45515 12.1739
311 1FP6 ADP 0.0009379 0.45246 12.1739
312 2QEN ADP 0.0001275 0.44331 12.1739
313 2G77 AF3 0.007847 0.43521 12.1739
314 2BME GNP 0.001609 0.42587 12.1739
315 1Z0K GTP 0.001692 0.42147 12.1739
316 1PVS 7HP 0.04711 0.41422 12.1739
317 1R6B ADP 0.0003886 0.41159 12.1739
318 3FWY ADP 0.00157 0.40204 12.1739
319 1MKY GDP 0.0001317 0.41067 12.3007
320 3RAB GNP 0.0008676 0.43702 12.426
321 4KAX GTP 0.001052 0.42448 12.426
322 2W83 GTP 0.001529 0.42328 12.7273
323 4XSH GSP 0.0009357 0.44374 12.7854
324 3RLF ANP 0.001996 0.41852 12.8378
325 3N5C GDP 0.0001517 0.50624 12.963
326 3LXR GDP 0.0008799 0.45849 13.0208
327 4DCT GDP 0.000175 0.49704 13.0435
328 4MKG AP5 0.0006527 0.46083 13.0435
329 4ZG4 VO4 ADP 0.0002243 0.45755 13.0435
330 4XGU ADP 0.0009223 0.44829 13.0435
331 3TNF GNP 0.002192 0.42347 13.0435
332 4LHW GNP 0.001285 0.4136 13.0435
333 3QBT GNP 0.001833 0.40753 13.0435
334 4RZ3 ADP 0.007737 0.40701 13.0435
335 4D81 ADP 0.00293 0.42987 13.0742
336 1UPT GTP 0.001674 0.41639 13.3333
337 3SBD GNP 0.001152 0.41519 13.369
338 4TTQ ATP 0.0002124 0.40775 13.4884
339 2RGX AP5 0.002453 0.43771 13.5922
340 2IYL GDP 0.001999 0.45141 13.7324
341 1G7C 5GP 0.008277 0.42114 13.8298
342 3IIJ ADP 0.0002099 0.40674 13.8889
343 2W58 ADP 0.00001805 0.58492 13.913
344 3LRE ADP 0.00001558 0.58038 13.913
345 4J0Q GDP 0.000112 0.51949 13.913
346 2CK3 ANP 0.0006065 0.45197 13.913
347 4R43 GDP 0.00327 0.44094 13.913
348 1G4U GDP 0.001199 0.43903 13.913
349 2V7Q ATP 0.0001071 0.43105 13.913
350 2CK3 ADP 0.001127 0.42872 13.913
351 1TQ4 GDP 0.0018 0.4275 13.913
352 2V7Q ADP 0.00007054 0.42028 13.913
353 5MEX SZZ 0.007071 0.41324 13.913
354 1T8U UAP SGN IDS SGN 0.01126 0.40644 13.913
355 3SFV GDP 0.003132 0.40109 13.913
356 3AB3 GDP 0.0004768 0.43198 14.0884
357 1ZCB GDP 0.001904 0.42283 14.0884
358 1S8F GDP 0.003994 0.41251 14.1243
359 3GJ8 GDP 0.0004243 0.47866 14.1304
360 3PQC GDP 0.0002929 0.48078 14.7826
361 5H56 ADP 0.006134 0.40746 14.7826
362 5H56 TYD 0.006134 0.40746 14.7826
363 1JJV ATP 0.000008065 0.4225 15.0485
364 3GJ4 GDP 0.0004042 0.40164 15.1515
365 3E5H GNP 0.003868 0.41002 15.1685
366 4DSU GDP 0.004871 0.40739 15.3439
367 1F2U ATP 0.002373 0.42046 15.4362
368 1J2J GTP 0.001589 0.42259 15.5556
369 5MZN ADP 0.001729 0.4655 15.6522
370 5G41 AP5 0.001352 0.45227 15.6522
371 5KDO GDP 0.001051 0.4375 15.6522
372 1VG0 GDP 0.0006192 0.41242 15.6522
373 1VG9 GDP 0.0006413 0.41161 15.6522
374 3BER AMP 0.0193 0.40303 15.6522
375 3DDC GNP 0.001756 0.40241 15.6522
376 5TB5 GDP 0.0007498 0.46173 15.6757
377 5TAR GDP 0.001019 0.45081 15.6757
378 3QF7 ANP 0.001367 0.41114 16
379 3CX8 GSP 0.0006317 0.40704 16.2722
380 2QTV GNP 0.0006847 0.4395 16.3265
381 1YTM ATP 0.001753 0.428 16.5217
382 1MR3 G3D 0.0005226 0.40354 16.5217
383 1Z0J GTP 0.001256 0.40799 16.9492
384 2HV8 GTP 0.001693 0.42495 17.1875
385 3GJ0 GDP 0.0002187 0.49846 17.3913
386 3NKV GNP 0.001294 0.4298 17.3913
387 4HAT GNP 0.001834 0.42673 17.3913
388 5UWP GNP 0.002015 0.425 17.3913
389 5UWI GNP 0.001964 0.4239 17.3913
390 3GJX GTP 0.002208 0.42178 17.3913
391 1Z2A GDP 0.002754 0.41276 17.3913
392 5UWH GNP 0.001659 0.40327 17.3913
393 5UWR GNP 0.001794 0.40212 17.3913
394 5UWQ GNP 0.001787 0.40209 17.3913
395 5UWO GNP 0.001808 0.40198 17.3913
396 5DHF GNP 0.001817 0.40188 17.3913
397 5DIF GNP 0.001864 0.40148 17.3913
398 5UWW GNP 0.002038 0.40037 17.3913
399 1NVV GNP 0.001763 0.42586 18.0723
400 1S3G AP5 0.0009126 0.45444 18.2609
401 4P4T GDP 0.000927 0.44392 18.2609
402 2OZE AGS 0.0004206 0.43121 18.2609
403 5SZH GNP 0.001754 0.42596 18.2609
404 3TKL GTP 0.001343 0.41892 18.2609
405 4P3Y GDP 0.00007043 0.41134 18.2609
406 2KIN ADP 0.000003044 0.41015 18.2609
407 2BIF ANP 0.008221 0.40583 18.2609
408 2BIF SIN 0.01348 0.40583 18.2609
409 3RWO GDP 0.005202 0.40466 18.2609
410 2A5J GDP 0.0007741 0.46108 18.3246
411 1G3Q ADP 0.001276 0.4558 18.5654
412 3CNL GNP 0.00003677 0.54377 19.1304
413 1BH2 GSP 0.0006997 0.44592 19.1304
414 1FQJ GDP 0.0008222 0.43436 19.1304
415 1FQK GDP 0.001107 0.42905 19.1304
416 1FQJ ALF 0.01177 0.42606 19.1304
417 1FQK ALF 0.01309 0.42356 19.1304
418 2A5F GTP 0.00179 0.42224 19.1304
419 1GOT GDP 0.001558 0.41785 19.1304
420 2ODE ALF GDP 0.0005353 0.41002 19.1304
421 1IBR GNP 0.001793 0.4023 19.1304
422 4HDQ GNP 0.002137 0.42237 19.2308
423 2VOH CIT 0.01367 0.41224 19.2308
424 1TU3 GNP 0.0007401 0.43989 19.2982
425 1R2Q GNP 0.001474 0.43925 19.4118
426 3MJH GTP 0.0007264 0.42278 19.6429
427 1Z6T ADP 0.0008313 0.45031 19.8675
428 1G7S GDP 0.0002995 0.48588 20
429 1PUJ GNP 0.0001454 0.43062 20
430 1Z0A GDP 0.0003433 0.41254 20.1149
431 1NY5 ADP 0.0008309 0.41298 20.155
432 1YRB GDP 0.00006593 0.50507 20.229
433 4R98 GNH 0.0006972 0.47381 20.2952
434 2XTN GTP 0.00329 0.40958 20.5128
435 3GJ5 GDP 0.0004183 0.40134 20.5882
436 3ZIA ADP 0.0004348 0.41569 20.6349
437 3ZIA ATP 0.0001784 0.41485 20.6349
438 2Y8E GNP 0.000595 0.42631 20.6704
439 1LFD GNP 0.002053 0.42146 20.6897
440 1G6O ADP 0.00006588 0.51102 20.8696
441 2OM2 GDP 0.000453 0.45315 20.8696
442 1SVK ALF GDP 0.0007744 0.4456 20.8696
443 1EK0 GNP 0.0006577 0.44202 20.8696
444 1Y3A GDP 0.001519 0.4234 20.8696
445 1GP2 GDP 0.002266 0.41624 20.8696
446 1NN5 ANP 0.006937 0.4065 20.9302
447 2FFQ GSP 0.0006843 0.44304 21.6374
448 5IFS ADP 0.0007232 0.4028 21.7391
449 3BC1 GNP 0.0009632 0.43514 22.0339
450 1SVI GDP 0.000104 0.40932 22.0513
451 5HCN GCP 0.00003089 0.53302 22.9885
452 1XMV ADP 0.00008464 0.43043 23.4783
453 3H4S ADP 0.00002065 0.40065 23.4783
454 2C04 GCP 0.009905 0.4022 24.2424
455 4M9Q GNP 0.0007621 0.43951 24.3478
456 5DI3 GNP 0.0008078 0.43845 24.3478
457 1B7T ADP 0.000155 0.49369 24.359
458 1KK8 BEF ADP 0.000287 0.47093 25.1799
459 4WZA ACP 0.003739 0.44334 25.2174
460 4WZA ADP 0.00476 0.4385 25.2174
461 3MBI HSX 0.02101 0.40517 25.2174
462 1R4A GNP 0.001755 0.42259 25.4902
463 1KO8 6PG 0.0006967 0.42084 25.7143
464 5UWT GNP 0.001941 0.42411 26.087
465 2D7C GTP 0.001991 0.42202 26.1905
466 2WKQ GTP 0.001467 0.42401 26.9565
467 2WIC GNP 0.00003122 0.5328 27.3408
468 5FTB ANP 0.0002444 0.48446 27.8261
469 5FHD ADP ALF 0.0006276 0.44709 27.8261
470 3ZQ6 ADP ALF 0.000129 0.47332 28.6957
471 2JLR ANP 0.0007239 0.40966 28.6957
472 3HSS MLA 0.01415 0.40535 29.5652
473 4YMU ATP 0.00004933 0.53736 31.3043
474 5XCO GDP 0.0009862 0.40201 33.3333
475 4OHY ANP 0.000000161 0.57586 48.7239
Pocket No.: 2; Query (leader) PDB : 4OI4; Ligand: ATP; Similar sites found: 8
This union binding pocket(no: 2) in the query (biounit: 4oi4.bio1) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5LFV SIA GAL NAG 0.04375 0.40352 3.78549
2 1LVG ADP 0.00009871 0.40138 6.06061
3 4C12 ADP 0.02394 0.40258 6.08696
4 3BD9 A3P 0.0164 0.40267 8.69565
5 1G16 GDP 0.004262 0.40028 13.0435
6 5E5U MLI 0.01536 0.40866 13.5678
7 3VX3 ADP 0.009154 0.4004 16.129
8 5UWJ GNP 0.001812 0.40209 17.3913
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