Receptor
PDB id Resolution Class Description Source Keywords
4ONQ 2.5 Å EC: 2.1.1.- CRYSTAL STRUCTURE OF NTDRM E283S/R309S/F310S/Y590S/D591S MUT NICOTIANA TABACUM DNA METHYLTRANSFERASE TRANSFERASE-TRANSFERASE INHIBITOR COM
Ref.: MOLECULAR MECHANISM OF ACTION OF PLANT DRM DE NOVO METHYLTRANSFERASES. CELL(CAMBRIDGE,MASS.) V. 157 1050 2014
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SFG A:700;
B:700;
Valid;
Valid;
none;
none;
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381.387 C15 H23 N7 O5 c1nc(...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4ONQ 2.5 Å EC: 2.1.1.- CRYSTAL STRUCTURE OF NTDRM E283S/R309S/F310S/Y590S/D591S MUT NICOTIANA TABACUM DNA METHYLTRANSFERASE TRANSFERASE-TRANSFERASE INHIBITOR COM
Ref.: MOLECULAR MECHANISM OF ACTION OF PLANT DRM DE NOVO METHYLTRANSFERASES. CELL(CAMBRIDGE,MASS.) V. 157 1050 2014
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 57 families.
1 4ONQ - SFG C15 H23 N7 O5 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 50 families.
1 4ONQ - SFG C15 H23 N7 O5 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 44 families.
1 4ONQ - SFG C15 H23 N7 O5 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SFG; Similar ligands found: 218
No: Ligand ECFP6 Tc MDL keys Tc
1 SFG 1 1
2 0UM 0.689655 0.887324
3 SAI 0.654762 0.940298
4 SA8 0.642857 0.9
5 SAH 0.635294 0.954545
6 EEM 0.62069 0.875
7 5X8 0.619048 0.924242
8 S7M 0.606742 0.875
9 RAB 0.597222 0.850746
10 XYA 0.597222 0.850746
11 ADN 0.597222 0.850746
12 5CD 0.594595 0.863636
13 5N5 0.581081 0.850746
14 62X 0.574468 0.84
15 A4D 0.573333 0.850746
16 K15 0.568421 0.863014
17 DTA 0.564103 0.84058
18 6RE 0.560976 0.833333
19 SAM 0.555556 0.875
20 EP4 0.551282 0.802817
21 KB1 0.55102 0.887324
22 M2T 0.544304 0.780822
23 SMM 0.537634 0.84
24 MTA 0.5375 0.826087
25 ZAS 0.53012 0.816901
26 A 0.53012 0.77027
27 AMP 0.53012 0.77027
28 J7C 0.529412 0.84507
29 3DH 0.52439 0.826087
30 GJV 0.523256 0.821918
31 SON 0.522727 0.813333
32 0XU 0.522222 0.938462
33 SRP 0.521277 0.813333
34 SSA 0.521277 0.697674
35 AMP MG 0.517647 0.75
36 AOC 0.517647 0.826087
37 CA0 0.516854 0.776316
38 5AL 0.516129 0.786667
39 AMO 0.515464 0.813333
40 DSZ 0.515464 0.717647
41 GSU 0.515152 0.738095
42 KH3 0.514286 0.851351
43 A2D 0.511628 0.75
44 A3N 0.511628 0.814286
45 ABM 0.511628 0.75
46 A5A 0.510638 0.682353
47 5CA 0.510417 0.697674
48 SRA 0.505882 0.730769
49 S4M 0.505747 0.792208
50 AN2 0.505618 0.74026
51 A7D 0.505618 0.882353
52 A3S 0.505618 0.895522
53 GAP 0.505376 0.776316
54 LSS 0.5 0.681818
55 VMS 0.5 0.666667
56 DSH 0.5 0.871429
57 AP2 0.5 0.766234
58 LAD 0.5 0.818182
59 ADX 0.5 0.678571
60 BA3 0.5 0.75
61 M33 0.5 0.74026
62 A12 0.5 0.766234
63 KAA 0.5 0.712644
64 54H 0.5 0.666667
65 Y3J 0.5 0.80303
66 SXZ 0.49505 0.875
67 ME8 0.49505 0.775
68 AHX 0.494949 0.759494
69 TSB 0.494845 0.674419
70 53H 0.494845 0.659091
71 G5A 0.494624 0.697674
72 50T 0.494505 0.74026
73 AP5 0.494382 0.75
74 5AS 0.494382 0.640449
75 ADP 0.494382 0.75
76 B4P 0.494382 0.75
77 8QN 0.489796 0.786667
78 GEK 0.489796 0.913043
79 5AD 0.486842 0.828125
80 PAJ 0.484848 0.728395
81 52H 0.484536 0.659091
82 AU1 0.483516 0.730769
83 ADP MG 0.483516 0.74026
84 MAO 0.483146 0.782051
85 NEC 0.482759 0.797101
86 A3G 0.482759 0.882353
87 3AM 0.482353 0.733333
88 YAP 0.480769 0.802632
89 7D7 0.480519 0.794118
90 TXA 0.480392 0.766234
91 NB8 0.480392 0.782051
92 NVA LMS 0.48 0.681818
93 DAL AMP 0.479592 0.786667
94 ATF 0.479167 0.721519
95 ATP 0.478261 0.75
96 BEF ADP 0.478261 0.721519
97 ACP 0.478261 0.753247
98 ADP BEF 0.478261 0.721519
99 A3T 0.478261 0.852941
100 7MD 0.476636 0.775
101 XAH 0.47619 0.775
102 YSA 0.47619 0.697674
103 PRX 0.473118 0.753247
104 APR 0.473118 0.773333
105 AR6 0.473118 0.773333
106 AQP 0.473118 0.75
107 APC 0.473118 0.766234
108 5FA 0.473118 0.75
109 WAQ 0.470588 0.815789
110 4AD 0.47 0.802632
111 NSS 0.47 0.697674
112 AD9 0.468085 0.730769
113 RBY 0.468085 0.789474
114 AGS 0.468085 0.7125
115 SAP 0.468085 0.7125
116 ADV 0.468085 0.789474
117 ADP PO3 0.468085 0.77027
118 A5D 0.468085 0.84058
119 MHZ 0.467391 0.782051
120 FA5 0.466667 0.813333
121 PTJ 0.466019 0.7375
122 00A 0.465347 0.746835
123 D3Y 0.464646 0.869565
124 ATP MG 0.463158 0.74026
125 VRT 0.463158 0.871429
126 LEU LMS 0.460784 0.662921
127 OOB 0.46 0.786667
128 S8M 0.46 0.859155
129 ADP VO4 0.459184 0.74026
130 VO4 ADP 0.459184 0.74026
131 ACQ 0.458333 0.753247
132 TAT 0.458333 0.721519
133 ANP 0.458333 0.730769
134 AAT 0.453608 0.847222
135 2AM 0.453488 0.723684
136 FYA 0.451923 0.786667
137 YLC 0.451327 0.797468
138 DLL 0.45098 0.786667
139 A3P 0.450549 0.746667
140 YLP 0.45045 0.777778
141 A22 0.45 0.74026
142 ADP ALF 0.44898 0.7125
143 ALF ADP 0.44898 0.7125
144 TYR AMP 0.448598 0.789474
145 2VA 0.446809 0.828571
146 3UK 0.446602 0.776316
147 OAD 0.446602 0.776316
148 ANP MG 0.444444 0.7125
149 IOT 0.443478 0.768293
150 9SN 0.443396 0.7375
151 P5A 0.442308 0.704545
152 PR8 0.442308 0.807692
153 7D5 0.44186 0.714286
154 A1R 0.441176 0.769231
155 7C5 0.440367 0.797297
156 TT8 0.44 0.926471
157 YLA 0.439655 0.777778
158 YLB 0.438596 0.777778
159 1ZZ 0.438095 0.753086
160 3OD 0.438095 0.776316
161 BIS 0.438095 0.725
162 NVA 2AD 0.4375 0.816901
163 MAP 0.435644 0.7125
164 MYR AMP 0.433962 0.753086
165 NAI 0.433628 0.725
166 SO8 0.43299 0.816901
167 A6D 0.432692 0.74359
168 5SV 0.431373 0.7375
169 25A 0.431373 0.75
170 TYM 0.429825 0.813333
171 WSA 0.429825 0.705882
172 3NZ 0.428571 0.833333
173 ARG AMP 0.428571 0.765432
174 LAQ 0.428571 0.753086
175 ADQ 0.427184 0.753247
176 7MC 0.426087 0.756098
177 48N 0.424779 0.759494
178 LPA AMP 0.424779 0.753086
179 JB6 0.424528 0.746835
180 PPS 0.424242 0.658824
181 AYB 0.423729 0.768293
182 PAP 0.42268 0.736842
183 OVE 0.422222 0.696203
184 3AD 0.421687 0.863636
185 4YB 0.419643 0.72093
186 CMP 0.419355 0.753425
187 2BA 0.419355 0.743243
188 A2P 0.419355 0.733333
189 ADP BMA 0.419048 0.753247
190 4UV 0.418182 0.75641
191 ALF ADP 3PG 0.417391 0.75
192 LA8 ALF 3PG 0.417391 0.75
193 AHZ 0.415929 0.731707
194 QQX 0.41573 0.670886
195 A A 0.415094 0.75
196 AP0 0.413793 0.695122
197 ATP A A A 0.412844 0.76
198 RP1 0.411111 0.705128
199 QQY 0.411111 0.679487
200 SP1 0.411111 0.705128
201 ACK 0.411111 0.716216
202 AFH 0.410714 0.728395
203 4UU 0.410714 0.75641
204 DND 0.408696 0.766234
205 TXD 0.408696 0.725
206 NXX 0.408696 0.766234
207 7D3 0.408602 0.696203
208 25L 0.407407 0.74026
209 CC5 0.407407 0.876923
210 TAD 0.40708 0.75
211 AMP DBH 0.405405 0.753247
212 TXE 0.405172 0.725
213 OMR 0.405172 0.743902
214 AF3 ADP 3PG 0.405172 0.75
215 MTP 0.404762 0.72973
216 N0B 0.401575 0.777778
217 V3L 0.4 0.773333
218 YLY 0.4 0.768293
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4ONQ; Ligand: SFG; Similar sites found: 317
This union binding pocket(no: 1) in the query (biounit: 4onq.bio2) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4I5I NAD 0.008833 0.40855 1.39373
2 4C3Y FAD 0.007726 0.42593 1.40056
3 4C3Y ANB 0.01069 0.42367 1.40056
4 5BR7 FAD 0.03264 0.40924 1.40056
5 5BR7 FLC 0.03725 0.40637 1.40056
6 1GET NAP 0.04836 0.40406 1.40056
7 1GET FAD 0.04603 0.40406 1.40056
8 5DX1 SFG 0.000007211 0.54281 1.43266
9 5DWQ SFG 0.00002562 0.51634 1.43266
10 5DX8 SFG 0.00003073 0.51075 1.43266
11 5DX0 SFG 0.00005006 0.50548 1.43266
12 5DXA SFG 0.00001972 0.47496 1.43266
13 2E5V FAD 0.01367 0.41603 1.68067
14 5EZ7 FAD 0.01269 0.41389 1.68067
15 1Y8Q ATP 0.001427 0.4035 1.7341
16 3GCZ SAM 0.000007669 0.52726 1.77305
17 3LCV SAM 0.0004287 0.46047 1.77936
18 2WA2 SAM 0.00003598 0.49139 1.81159
19 1U7T TDT 0.02636 0.40074 1.91571
20 2DFV NAD 0.01147 0.40346 2.01729
21 1XSE NDP 0.01015 0.41939 2.0339
22 3CH6 311 0.01545 0.42532 2.0979
23 3CH6 NAP 0.01545 0.42532 2.0979
24 3EVG SAH 0.000004964 0.53537 2.18182
25 3QOX SAH 0.000004351 0.54803 2.2409
26 4N49 SAM 0.00001042 0.52667 2.2409
27 1U2Z SAH 0.00002556 0.51426 2.2409
28 4LWP SAH 0.00002669 0.50402 2.2409
29 4DMG SAM 0.000262 0.48221 2.2409
30 3L9W AMP 0.001157 0.45254 2.2409
31 3L9W GSH 0.001267 0.44789 2.2409
32 4MIG G3F 0.0137 0.42011 2.2409
33 2Q28 ADP 0.003127 0.41716 2.2409
34 1MO9 KPC 0.03752 0.4147 2.2409
35 3UCL NAP 0.03382 0.41191 2.2409
36 3UCL CYH 0.0313 0.41191 2.2409
37 3UCL FAD 0.0313 0.41191 2.2409
38 2RGO FAD 0.01543 0.40795 2.2409
39 2HQM FAD 0.02638 0.40158 2.2409
40 2P41 SAH 0.00000446 0.53736 2.29508
41 4YUW 4JU 0.005593 0.46485 2.30263
42 4YUW S4M 0.005484 0.46485 2.30263
43 5MW4 5JU 0.00001734 0.54893 2.39521
44 4RDH AMP 0.008564 0.40328 2.43056
45 5E1M PRO PRO LYS ARG ILE ALA 0.0003558 0.48003 2.48963
46 5E1M SAH 0.0003558 0.48003 2.48963
47 4KIB SAH 0.00005499 0.48462 2.52101
48 2C31 TZD 0.01643 0.42931 2.52101
49 2C31 ADP 0.01601 0.42931 2.52101
50 1QO8 FAD 0.0201 0.4072 2.52101
51 4A6D SAM 0.001457 0.42332 2.54958
52 2YY7 NAD 0.01443 0.40272 2.5641
53 1XTP SAI 0.000462 0.45087 2.75591
54 5UAV TFB 0.01236 0.41141 2.79503
55 5UAV NDP 0.01236 0.41141 2.79503
56 5THZ SAH 0.000009221 0.53371 2.80112
57 5THY SAH 0.000009791 0.52785 2.80112
58 1D4D FAD 0.004231 0.44015 2.80112
59 1V59 FAD 0.009845 0.42454 2.80112
60 3S5W FAD 0.009578 0.41084 2.80112
61 1ELI PYC 0.01485 0.40971 2.80112
62 1WVG APR 0.009874 0.40357 2.80112
63 1V59 NAD 0.002261 0.40267 2.80112
64 1KNR FAD 0.02489 0.40103 2.80112
65 3NTD FAD 0.02337 0.40047 2.80112
66 5XVK SAH 0.0005446 0.45591 2.8169
67 5XVQ SAH 0.000233 0.43442 2.8169
68 3VYW SAM 0.0000174 0.49535 2.92208
69 3WLE NAD 0.01369 0.40935 2.93255
70 2YX1 SFG 0.00002996 0.48037 2.97619
71 3T7S SAM 0.000007807 0.52693 2.98507
72 1UWK NAD 0.001688 0.46095 3.08123
73 4RPL 3UC 0.01676 0.42661 3.08123
74 4RPL FAD 0.02315 0.41786 3.08123
75 1V8K ANP 0.01109 0.40969 3.08123
76 4XQC NAD 0.02109 0.40707 3.08123
77 4XQC 13D 0.02994 0.40061 3.08123
78 5K7U SAM 0.001516 0.42872 3.11111
79 1SB8 NAD 0.01946 0.412 3.125
80 1SB8 UD2 0.02243 0.412 3.125
81 3U4C NDP 0.00357 0.42764 3.20285
82 1UAY ADN 0.0007496 0.45564 3.30579
83 4YMH SAH 0.00005283 0.49605 3.33333
84 1SQF SAM 0.00002504 0.50521 3.36134
85 5KOK SAH 0.0001106 0.47988 3.36134
86 5KOK S9T 0.0004145 0.47699 3.36134
87 5KOK R9T 0.0008943 0.46036 3.36134
88 3VSE SAH 0.0002348 0.43779 3.36134
89 5JAQ NAI 0.01096 0.41686 3.36134
90 1RSG FAD 0.01853 0.40888 3.36134
91 2RAB FAD 0.02264 0.40643 3.36134
92 2RAB NAD 0.0413 0.40643 3.36134
93 4YRY NAD 0.0376 0.40172 3.36134
94 4YRY FAD 0.0262 0.40172 3.36134
95 4PIO SAH 0.0004246 0.47651 3.40557
96 4PIO AVI 0.0004384 0.47451 3.40557
97 2AG8 NAP 0.002691 0.42187 3.42205
98 2PT9 S4M 0.0007527 0.45325 3.42679
99 2PT9 2MH 0.001365 0.45325 3.42679
100 2BZG SAH 0.00001216 0.51866 3.44828
101 4BLW AMP 0.0004658 0.47467 3.46021
102 4BLW SAH 0.0004591 0.46449 3.46021
103 1G60 SAM 0.000001057 0.56708 3.46154
104 4R6W SAH 0.00009184 0.40523 3.48837
105 4KRG SAH 0.00002824 0.49617 3.64146
106 5X62 SAH 0.000108 0.47231 3.64146
107 3TKY SAH 0.0005823 0.44871 3.64146
108 5FA5 MTA 0.000484 0.43903 3.64146
109 1KYZ SAH 0.002211 0.42167 3.64146
110 1KYZ FER 0.005803 0.41675 3.64146
111 1ZGA SAH 0.001461 0.415 3.64146
112 4D7E FAD 0.01121 0.41337 3.64146
113 2JAH NDP 0.008239 0.41382 3.64372
114 2PX8 SAH 0.00005238 0.49145 3.71747
115 3LKZ SFG 0.00001092 0.52329 3.73832
116 1NW5 SAM 0.000003308 0.54569 3.76176
117 3CTY FAD 0.0113 0.42082 3.76176
118 1JQD SAH 0.0002879 0.40318 3.76712
119 4GQB 0XU 0.0001002 0.4902 3.77907
120 2BL9 NDP 0.01951 0.40218 3.78151
121 2BL9 CP6 0.01951 0.40218 3.78151
122 1O97 FAD 0.01652 0.42058 3.78788
123 1O97 AMP 0.01652 0.42058 3.78788
124 1Q0S SAH 0.00006308 0.49906 3.861
125 2UYQ SAM 0.004368 0.44207 3.87097
126 3UOY NAP 0.04485 0.40463 3.92157
127 3UOY FAD 0.04485 0.40463 3.92157
128 5KVA SAM 0.000005032 0.54288 3.95683
129 4M7V RAR 0.01671 0.41189 4
130 4M7V NAP 0.01494 0.40203 4
131 5J60 FAD 0.012 0.41598 4.0625
132 3H8V ATP 0.006841 0.40058 4.10959
133 5BW4 SAM 0.0001786 0.46331 4.11985
134 3JWH SAH 0.0001043 0.4551 4.14747
135 5JGL SAM 0.0000692 0.48026 4.15225
136 2HNK SAH 0.00002279 0.51191 4.1841
137 4NTD FAD 0.004916 0.43213 4.20168
138 4EUE NAI 0.005808 0.42198 4.20168
139 3ICT FAD 0.008746 0.41943 4.20168
140 3ICR FAD 0.009216 0.41838 4.20168
141 3ICS FAD 0.01082 0.41614 4.20168
142 1GPE FAD 0.02227 0.4076 4.20168
143 3GD4 FAD 0.04097 0.40248 4.20168
144 5LOG SAH 0.000188 0.46992 4.29185
145 3GXO SAH 0.003192 0.42255 4.33604
146 3GWZ SAH 0.002377 0.40708 4.33604
147 1Z3C SA8 0.0001418 0.49231 4.36242
148 1P77 ATR 0.009736 0.42149 4.41176
149 5BVA FAD 0.002678 0.4505 4.48179
150 3LAD FAD 0.01118 0.41928 4.48179
151 1GY8 NAD 0.01017 0.40965 4.48179
152 3RFV NAI 0.008881 0.40845 4.49438
153 3RFV 15L 0.01083 0.40321 4.49438
154 1PR9 NAP 0.005412 0.42459 4.5082
155 3D3W NAP 0.006115 0.42216 4.5082
156 5HJM MTA 0.00003247 0.4914 4.54545
157 3OU2 SAH 0.00002347 0.45617 4.58716
158 5A3B APR 0.005006 0.4182 4.62046
159 3TN7 NJP 0.007634 0.41533 4.66926
160 3G2O SAM 0.0001592 0.47073 4.68227
161 3ITJ CIT 0.02195 0.40209 4.73373
162 1R6D NAD 0.01534 0.42075 4.74777
163 1R6D DAU 0.01482 0.42075 4.74777
164 2XVF FAD 0.02061 0.40207 4.7619
165 2XVE FAD 0.04797 0.40029 4.7619
166 2VDV SAM 0.00006981 0.50296 4.87805
167 3LST SAH 0.001454 0.44243 4.88506
168 3TKA SAM 0.00006536 0.49203 4.89914
169 5E72 SAM 0.0000006228 0.58252 4.91329
170 5GT9 NAP 0.007815 0.41486 4.94297
171 5L95 AMP 0.004268 0.41132 5
172 1P1C SAH 0.001587 0.4355 5.02513
173 4AZW SAM 0.0001683 0.47199 5.04202
174 4AZT SAM 0.0001543 0.47131 5.04202
175 5BUK FAD 0.01467 0.41543 5.04202
176 2V6G NAP 0.009233 0.41157 5.04202
177 3MQ2 SAH 0.0002866 0.46453 5.04587
178 1DL5 SAH 0.000001453 0.5759 5.04732
179 5GM1 SAH 0.0000143 0.52534 5.05051
180 3MB5 SAM 0.00001595 0.48131 5.09804
181 5CUQ NSC 0.000006995 0.55491 5.24345
182 1IY8 NAD 0.01579 0.40094 5.24345
183 3H2B SAH 0.00003327 0.5024 5.32213
184 3AD8 FAD 0.0196 0.42264 5.32213
185 3AD8 PYC 0.0196 0.42264 5.32213
186 3AD8 NAD 0.01594 0.40415 5.32213
187 3PFG SAM 0.03359 0.4199 5.32319
188 1XHL NDP 0.007582 0.41669 5.38721
189 3BXO SAM 0.0002193 0.44868 5.43933
190 3DXY SAM 0.00009753 0.50238 5.50459
191 5FJN BE2 0.026 0.40436 5.60224
192 5FJN FAD 0.02306 0.40436 5.60224
193 4MO2 FDA 0.0213 0.40139 5.60224
194 3A25 SAM 0.00002979 0.50197 5.64784
195 1FP2 SAH 0.01566 0.40558 5.68182
196 1LSS NAD 0.0002812 0.4645 5.71429
197 5N5D SAM 0.0001167 0.47886 5.75221
198 2BGM NAJ 0.007628 0.41002 5.7554
199 2CJU PHX 0.01199 0.42111 5.78512
200 3S1S SAH 0.0000253 0.47159 5.88235
201 1FP1 SAH 0.0004249 0.44174 5.88235
202 1Q9I TEO 0.01716 0.42046 5.88235
203 1U72 NDP 0.03211 0.40369 5.91398
204 1BC5 SAH 0.00249 0.4269 5.94796
205 5ULP KB1 0.00000328 0.55575 5.97015
206 4POO SAM 0.00003274 0.51164 6
207 2PZM NAD 0.01384 0.41578 6.06061
208 2PZM UDP 0.01384 0.41578 6.06061
209 1XKQ NDP 0.004633 0.42768 6.07143
210 5N53 8NB 0.02346 0.40437 6.15385
211 1F3L SAH 0.00001178 0.49156 6.23053
212 5FTW SAH 0.0005041 0.45349 6.25
213 1TPY SAH 0.000007387 0.5356 6.27178
214 4UCI SAM 0.00009565 0.48259 6.44258
215 4TQG NDP 0.001756 0.44151 6.50155
216 4ZCC FAD 0.02513 0.40888 6.54762
217 4ZCC NAI 0.02513 0.40888 6.54762
218 5DY5 5GR 0.03189 0.40913 6.57895
219 1R18 SAH 0.000004135 0.54661 6.60793
220 4PNE SAH 0.00001115 0.53008 6.62252
221 4X9M FAD 0.006897 0.42728 6.69856
222 5JJR SAH 0.00001091 0.52069 6.72269
223 5T67 JHZ 0.002007 0.45738 6.72269
224 5T67 SAH 0.001584 0.45722 6.72269
225 4RSL FAD 0.006686 0.42379 6.72269
226 1NVM NAD 0.007995 0.41683 6.72269
227 4DCM SAM 0.00217 0.41279 6.72269
228 2GVC FAD 0.01506 0.40419 6.72269
229 2AG5 NAD 0.008813 0.41123 6.91057
230 1QAN SAH 0.000001442 0.5666 6.96721
231 2PXX SAH 0.0002704 0.4631 6.97674
232 4J56 FAD 0.02993 0.40063 7.01754
233 1RP0 AHZ 0.004404 0.42746 7.04225
234 3P2E SAH 0.0004066 0.44009 7.11111
235 1I9G SAM 0.000008575 0.53035 7.14286
236 5F8F SFG 0.0006591 0.4338 7.1618
237 5MGZ SAH 0.0000386 0.49961 7.20339
238 1N4W FAD 0.0141 0.41539 7.28291
239 5I39 FAD 0.01439 0.41036 7.28291
240 3GEG NAD 0.001644 0.44132 7.28745
241 2ZFU SAH 0.001529 0.43255 7.44186
242 3FZG SAM 0.005019 0.41372 7.5
243 2EJU SAH 0.0001891 0.46752 7.56302
244 3IHG FAD 0.007862 0.41218 7.56302
245 3C3Y SAH 0.00007268 0.48774 7.59494
246 1M0U GSH 0.01985 0.40711 7.63052
247 3Q87 SAM 0.0009293 0.44571 7.64706
248 1NFQ NAI 0.01287 0.40617 7.69231
249 1I1N SAH 0.000004305 0.55693 7.9646
250 5FA8 SAM 0.00001576 0.52349 8.07453
251 4NEC SAH 0.000117 0.48699 8.33333
252 1KPG SAH 0.000005644 0.50224 8.36237
253 4KRI SAH 0.00005349 0.49582 8.40336
254 4D04 NAP 0.03263 0.40984 8.40336
255 4D04 FAD 0.03263 0.40984 8.40336
256 5GWX SAM 0.001921 0.43677 8.4507
257 5GWX SAR 0.001921 0.43677 8.4507
258 3HVJ 705 0.00001201 0.55212 8.59729
259 1X87 NAD 0.001574 0.43565 8.68347
260 5ODQ FAD 0.01067 0.42023 8.69565
261 1L1E SAH 0.000004465 0.54266 8.7108
262 3A27 SAM 0.00003225 0.50049 8.82353
263 5E8J SAH 0.0002439 0.47802 8.97436
264 5E9W SAH 0.0004016 0.4318 8.97436
265 1XHC FAD 0.006958 0.42298 8.99183
266 4FC7 NAP 0.01846 0.40896 9.02527
267 4FC7 COA 0.01846 0.40896 9.02527
268 1KPH SAH 0.000007665 0.5349 9.05923
269 2ZIF SAM 0.00000007712 0.61618 9.09091
270 4XUC SAM 0.00004195 0.52261 9.17431
271 4XUC 43G 0.00004195 0.52261 9.17431
272 3C6K MTA 0.003016 0.43979 9.18635
273 3C6K SPD 0.003016 0.43979 9.18635
274 1L3I SAH 0.0000007491 0.58872 9.375
275 5IL1 SAM 0.001053 0.43551 9.43396
276 1BZL FAD 0.04381 0.41644 9.52381
277 2AWN ADP 0.03732 0.40864 9.52381
278 1FEC FAD 0.03209 0.40074 9.52381
279 4YSX FAD 0.0151 0.41129 9.61539
280 1VE3 SAM 0.0002095 0.46561 9.69163
281 2BRY FAD 0.01798 0.40064 9.80392
282 3BGD SAH 0.00001509 0.52431 10
283 3BGD PM6 0.00003787 0.51465 10
284 2GAG FAD 0.01133 0.42162 10
285 2GAG FOA 0.01427 0.41684 10
286 2GAG NAD 0.01384 0.41014 10
287 2XVM SAH 0.0007546 0.42841 10.5528
288 4OBW SAM 0.001881 0.42469 10.8949
289 5MPT SAH 0.000009551 0.52317 10.9244
290 2R4J 13P 0.03948 0.4 10.9244
291 2AE2 NAP 0.01829 0.40736 11.1538
292 2AE2 PTO 0.01829 0.40736 11.1538
293 2DPM SAM 0.00005376 0.49794 11.2676
294 2OBF SAH 0.00056 0.48055 11.4187
295 2OBF F83 0.00056 0.48055 11.4187
296 4QED NAP 0.01449 0.40143 12.0968
297 5DNK SAH 0.00008567 0.44629 12.3249
298 1SQL GUN 0.02556 0.40676 12.3288
299 2A14 SAH 0.000652 0.4506 12.5475
300 2HMT NAI 0.006666 0.40644 13.1944
301 5ITV NAI 0.007204 0.41647 13.3333
302 2DTX BMA 0.01905 0.4056 13.6364
303 1AE1 NAP 0.01747 0.40122 13.9194
304 1JG3 ADN 0.0001942 0.46702 14.0426
305 3PT9 SAH 0.0000000006096 0.70319 14.8459
306 3QDW A2G 0.03044 0.40215 15.3846
307 2PWY SAH 0.000001674 0.56625 15.8915
308 2ZAT NAP 0.007928 0.41332 16.1538
309 1G55 SAH 0.000000002225 0.66299 16.3265
310 2WSB NAD 0.02055 0.40496 18.1102
311 2AOT SAH 0.00005881 0.47597 18.1507
312 2F5Z FAD 0.01008 0.4223 18.75
313 1XDS SAM 0.002185 0.4343 18.7675
314 5JE0 SAH 0.0001256 0.49627 21.8623
315 5JE0 AZ8 0.0001256 0.49627 21.8623
316 1WUW TSU 0.007594 0.4304 22.2222
317 3RNM FAD 0.0135 0.41629 29.3103
Pocket No.: 2; Query (leader) PDB : 4ONQ; Ligand: SFG; Similar sites found: 16
This union binding pocket(no: 2) in the query (biounit: 4onq.bio1) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4REP FAD 0.01514 0.41029 1.96078
2 5AOA PPI 0.01274 0.40514 2.0979
3 2RGH FAD 0.02356 0.40216 2.2409
4 1JQD HSM 0.0003171 0.40954 3.76712
5 3EF0 ALF 0.0218 0.4034 4.20168
6 5U8U FAD 0.03961 0.40679 4.48179
7 1KUJ MMA 0.002254 0.45176 4.51128
8 1JAC AMG 0.006256 0.41166 4.51128
9 5XLX SAH 0.002387 0.42025 4.96454
10 3EVF SAH 0.00001994 0.40227 6.85921
11 2W58 ADP 0.03572 0.4023 7.42574
12 5F2K OCA 0.01529 0.40275 7.84314
13 5F2K SAH 0.01529 0.40275 7.84314
14 2CBZ ATP 0.0319 0.40506 9.2827
15 1NM5 NAD 0.03758 0.40105 13.7931
16 1QZZ SAM 0.0008855 0.42594 18.7675
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